TY  - JOUR
AU  - Avdalović, Jelena
AU  - Miletić, Srđan
AU  - Božović, Olga
AU  - Šolević Knudsen, Tatjana
AU  - Stanković, Dalibor M.
AU  - Lugonja, Nikoleta
AU  - Spasić, Snežana D.
AU  - Joksimović, Kristina
AU  - Dragičević, Igor
AU  - Vrvić, Miroslav M.
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9895
AB  - The aim of this study was to investigate the creation of humic substances during biodegradation of heavy residual fuel oil, because there are indications that substances similar to humic substances are generated during biodegradation of polycyclic aromatic hydrocarbons. In the study, which lasted for 110 days, biodegradation of heavy residual fuel oil was carried out in a layer of artificial soil substrate. The initial concentration of the total petroleum hydrocarbon in the prepared artificial soil substrate (biopile) was 23.1 g kg-1 dry weight (d.w.). At the end of the process, the total petroleum hydrocarbons were reduced to 8.1 g kg-1 d.w. in the inoculated biopile, while the content of humic acids increased during bioremediation from 3.15 g kg-1 d.w. to 4.95 g kg-1 d.w. The humic acids extracted from biopile during the biodegradation process were characterized by various chemical techniques (elemental analysis, spectrofluorimetric analysis, electrochemical measurements, and size exclusion chromatography). The results showed that levels of C, H and the H/C ratio decreased as the biodegradation process progressed. This indicated that humic acids aromatization process took place and this was confirmed by the spectrofluorimetric analysis. The increase of oxygen percentage and the O/C ratio in the humic acids after the biodegradation treatment indicated an increase in functional oxygen groups. Additional analyses of humic acids from the inoculated biopile showed that they were transformed during the bioremediation process. They had greater redox and buffering capacities and a larger portion of the fractions had high molecular mass. Also, the humification parameters (the CHAs/CFAs ratio and CHAs/Corg ratio) increased during the biodegradation. This is one of the few studies that describes the generation of humic substances during the biodegradation of oil compounds.
T2  - Science of the Total Environment
T1  - Study on the assessment of humification processes during biodegradation of heavy residual fuel oil
VL  - 797
SP  - 149099
DO  - 10.1016/j.scitotenv.2021.149099
ER  - 

@article{
author = "Avdalović, Jelena and Miletić, Srđan and Božović, Olga and Šolević Knudsen, Tatjana and Stanković, Dalibor M. and Lugonja, Nikoleta and Spasić, Snežana D. and Joksimović, Kristina and Dragičević, Igor and Vrvić, Miroslav M.",
year = "2021",
abstract = "The aim of this study was to investigate the creation of humic substances during biodegradation of heavy residual fuel oil, because there are indications that substances similar to humic substances are generated during biodegradation of polycyclic aromatic hydrocarbons. In the study, which lasted for 110 days, biodegradation of heavy residual fuel oil was carried out in a layer of artificial soil substrate. The initial concentration of the total petroleum hydrocarbon in the prepared artificial soil substrate (biopile) was 23.1 g kg-1 dry weight (d.w.). At the end of the process, the total petroleum hydrocarbons were reduced to 8.1 g kg-1 d.w. in the inoculated biopile, while the content of humic acids increased during bioremediation from 3.15 g kg-1 d.w. to 4.95 g kg-1 d.w. The humic acids extracted from biopile during the biodegradation process were characterized by various chemical techniques (elemental analysis, spectrofluorimetric analysis, electrochemical measurements, and size exclusion chromatography). The results showed that levels of C, H and the H/C ratio decreased as the biodegradation process progressed. This indicated that humic acids aromatization process took place and this was confirmed by the spectrofluorimetric analysis. The increase of oxygen percentage and the O/C ratio in the humic acids after the biodegradation treatment indicated an increase in functional oxygen groups. Additional analyses of humic acids from the inoculated biopile showed that they were transformed during the bioremediation process. They had greater redox and buffering capacities and a larger portion of the fractions had high molecular mass. Also, the humification parameters (the CHAs/CFAs ratio and CHAs/Corg ratio) increased during the biodegradation. This is one of the few studies that describes the generation of humic substances during the biodegradation of oil compounds.",
journal = "Science of the Total Environment",
title = "Study on the assessment of humification processes during biodegradation of heavy residual fuel oil",
volume = "797",
pages = "149099",
doi = "10.1016/j.scitotenv.2021.149099"
}

Avdalović, J., Miletić, S., Božović, O., Šolević Knudsen, T., Stanković, D. M., Lugonja, N., Spasić, S. D., Joksimović, K., Dragičević, I.,& Vrvić, M. M.. (2021). Study on the assessment of humification processes during biodegradation of heavy residual fuel oil. in Science of the Total Environment, 797, 149099.
https://doi.org/10.1016/j.scitotenv.2021.149099

Avdalović J, Miletić S, Božović O, Šolević Knudsen T, Stanković DM, Lugonja N, Spasić SD, Joksimović K, Dragičević I, Vrvić MM. Study on the assessment of humification processes during biodegradation of heavy residual fuel oil. in Science of the Total Environment. 2021;797:149099.
doi:10.1016/j.scitotenv.2021.149099 .

Avdalović, Jelena, Miletić, Srđan, Božović, Olga, Šolević Knudsen, Tatjana, Stanković, Dalibor M., Lugonja, Nikoleta, Spasić, Snežana D., Joksimović, Kristina, Dragičević, Igor, Vrvić, Miroslav M., "Study on the assessment of humification processes during biodegradation of heavy residual fuel oil" in Science of the Total Environment, 797 (2021):149099,
https://doi.org/10.1016/j.scitotenv.2021.149099 . .

TY  - JOUR
AU  - Lugonja, N. M.
AU  - Stanković, Dalibor M.
AU  - Milicic, B.
AU  - Spasić, Snežana D.
AU  - Marinkovic, V.
AU  - Vrvić, Miroslav M.
PY  - 2018
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/1738
AB  - The electrochemical techniques were used to determine the total antioxidant capacity of breast milks and the results were compared with a commonly used spectrophotometric (2,2-diphenyl-1-picrylhydrazyl, DPPH) method. Breast milk from mothers of preterm infants was monitored in three lactation phases and after storage of expressed milk by monitoring changes in the total antioxidant capacity over a two year period. Statistical analysis showed there was no significant difference between the ability of the three methods to detect changes in breast milk after storage. Either of the electrochemical techniques studied could be successfully used to replace the time-consuming spectrophotometric method and can be applied to clinical trials.
T2  - Food Chemistry
T1  - Electrochemical monitoring of the breast milk quality
VL  - 240
SP  - 567
EP  - 572
DO  - 10.1016/j.foodchem.2017.07.164
ER  - 

@article{
author = "Lugonja, N. M. and Stanković, Dalibor M. and Milicic, B. and Spasić, Snežana D. and Marinkovic, V. and Vrvić, Miroslav M.",
year = "2018",
abstract = "The electrochemical techniques were used to determine the total antioxidant capacity of breast milks and the results were compared with a commonly used spectrophotometric (2,2-diphenyl-1-picrylhydrazyl, DPPH) method. Breast milk from mothers of preterm infants was monitored in three lactation phases and after storage of expressed milk by monitoring changes in the total antioxidant capacity over a two year period. Statistical analysis showed there was no significant difference between the ability of the three methods to detect changes in breast milk after storage. Either of the electrochemical techniques studied could be successfully used to replace the time-consuming spectrophotometric method and can be applied to clinical trials.",
journal = "Food Chemistry",
title = "Electrochemical monitoring of the breast milk quality",
volume = "240",
pages = "567-572",
doi = "10.1016/j.foodchem.2017.07.164"
}

Lugonja, N. M., Stanković, D. M., Milicic, B., Spasić, S. D., Marinkovic, V.,& Vrvić, M. M.. (2018). Electrochemical monitoring of the breast milk quality. in Food Chemistry, 240, 567-572.
https://doi.org/10.1016/j.foodchem.2017.07.164

Lugonja NM, Stanković DM, Milicic B, Spasić SD, Marinkovic V, Vrvić MM. Electrochemical monitoring of the breast milk quality. in Food Chemistry. 2018;240:567-572.
doi:10.1016/j.foodchem.2017.07.164 .

Lugonja, N. M., Stanković, Dalibor M., Milicic, B., Spasić, Snežana D., Marinkovic, V., Vrvić, Miroslav M., "Electrochemical monitoring of the breast milk quality" in Food Chemistry, 240 (2018):567-572,
https://doi.org/10.1016/j.foodchem.2017.07.164 . .

TY  - JOUR
AU  - Jednak, Tanja
AU  - Avdalović, Jelena
AU  - Miletić, Srđan
AU  - Slavković-Beškoski, Latinka J.
AU  - Stanković, Dalibor M.
AU  - Milić, Jelena
AU  - Ilić, Mila
AU  - Beškoski, Vladimir P.
AU  - Gojgić-Cvijović, Gordana
AU  - Vrvić, Miroslav M.
PY  - 2017
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/1611
AB  - The aim of this paper was to investigate whether changes in the quantity and structure of humic acids (HA) occur during bioremediation of waste mazute (heavy residual fuel oil). The effects of humification on the structure of HA were evaluated by Fourier Transform Infrared Spectroscopy (FT-IR), potentiometric titrations, the ratio of absorbances at 465 and 665 nm (E4/E6 ratio) and the ratio. Also, the quality of humification was monitored by determining parameters which are important for measuring the evolution of humic substances (HS), such as CHA/CFA (the humic acidifulvic acidratio), the rate of extraction (TE) and the index of polymerization (IP). An increase of the content of HA from 0.23% to 0.70% was observed during the bioremediation process. The FT-IR spectra and 04 ratio of HA extracted at the beginning and the end of the process indicate structural changes during the bioremediation process. The groups containing aromatic and carboxylic carbon increased, resulting in HA structures of higher aromaticity. An increase of the B4/E6 ratio during bioremediation treatment implied the enrichment of HA with functional oxygen groups. Potentiometric titrations of HA solution showed increases in the buffering and the redox capacities of HA during the bioremediation process. The results of parameters of humification showed an increase of the compositional carbon in HA at the end, compared to at the start, of bioremediation, while the carbon that belonged to fulvic acids (FA) reduced by 44%. Transformation into HA is the likely cause of this observed reduction. The TE and the IP demonstrated that humification occured during the bioremediation process. According to the available data, this is the first report on synthesis of HS during bioremediation of petroleum hydrocarbons. (C) 2017 Published by Elsevier Ltd.
T2  - International Biodeterioration and Biodegradation
T1  - Transformation and synthesis of humic substances during bioremediation of petroleum hydrocarbons
VL  - 122
SP  - 47
EP  - 52
DO  - 10.1016/j.ibiod.2017.04.009
ER  - 

@article{
author = "Jednak, Tanja and Avdalović, Jelena and Miletić, Srđan and Slavković-Beškoski, Latinka J. and Stanković, Dalibor M. and Milić, Jelena and Ilić, Mila and Beškoski, Vladimir P. and Gojgić-Cvijović, Gordana and Vrvić, Miroslav M.",
year = "2017",
abstract = "The aim of this paper was to investigate whether changes in the quantity and structure of humic acids (HA) occur during bioremediation of waste mazute (heavy residual fuel oil). The effects of humification on the structure of HA were evaluated by Fourier Transform Infrared Spectroscopy (FT-IR), potentiometric titrations, the ratio of absorbances at 465 and 665 nm (E4/E6 ratio) and the ratio. Also, the quality of humification was monitored by determining parameters which are important for measuring the evolution of humic substances (HS), such as CHA/CFA (the humic acidifulvic acidratio), the rate of extraction (TE) and the index of polymerization (IP). An increase of the content of HA from 0.23% to 0.70% was observed during the bioremediation process. The FT-IR spectra and 04 ratio of HA extracted at the beginning and the end of the process indicate structural changes during the bioremediation process. The groups containing aromatic and carboxylic carbon increased, resulting in HA structures of higher aromaticity. An increase of the B4/E6 ratio during bioremediation treatment implied the enrichment of HA with functional oxygen groups. Potentiometric titrations of HA solution showed increases in the buffering and the redox capacities of HA during the bioremediation process. The results of parameters of humification showed an increase of the compositional carbon in HA at the end, compared to at the start, of bioremediation, while the carbon that belonged to fulvic acids (FA) reduced by 44%. Transformation into HA is the likely cause of this observed reduction. The TE and the IP demonstrated that humification occured during the bioremediation process. According to the available data, this is the first report on synthesis of HS during bioremediation of petroleum hydrocarbons. (C) 2017 Published by Elsevier Ltd.",
journal = "International Biodeterioration and Biodegradation",
title = "Transformation and synthesis of humic substances during bioremediation of petroleum hydrocarbons",
volume = "122",
pages = "47-52",
doi = "10.1016/j.ibiod.2017.04.009"
}

Jednak, T., Avdalović, J., Miletić, S., Slavković-Beškoski, L. J., Stanković, D. M., Milić, J., Ilić, M., Beškoski, V. P., Gojgić-Cvijović, G.,& Vrvić, M. M.. (2017). Transformation and synthesis of humic substances during bioremediation of petroleum hydrocarbons. in International Biodeterioration and Biodegradation, 122, 47-52.
https://doi.org/10.1016/j.ibiod.2017.04.009

Jednak T, Avdalović J, Miletić S, Slavković-Beškoski LJ, Stanković DM, Milić J, Ilić M, Beškoski VP, Gojgić-Cvijović G, Vrvić MM. Transformation and synthesis of humic substances during bioremediation of petroleum hydrocarbons. in International Biodeterioration and Biodegradation. 2017;122:47-52.
doi:10.1016/j.ibiod.2017.04.009 .

Jednak, Tanja, Avdalović, Jelena, Miletić, Srđan, Slavković-Beškoski, Latinka J., Stanković, Dalibor M., Milić, Jelena, Ilić, Mila, Beškoski, Vladimir P., Gojgić-Cvijović, Gordana, Vrvić, Miroslav M., "Transformation and synthesis of humic substances during bioremediation of petroleum hydrocarbons" in International Biodeterioration and Biodegradation, 122 (2017):47-52,
https://doi.org/10.1016/j.ibiod.2017.04.009 . .

TY  - JOUR
AU  - Jeremić, Sanja
AU  - Beškoski, Vladimir P.
AU  - Đokić, Lidija
AU  - Vasiljević, Branka
AU  - Vrvić, Miroslav M.
AU  - Avdalović, Jelena
AU  - Gojgić-Cvijović, Gordana
AU  - Slavković-Beškoski, Latinka J.
AU  - Nikodinović-Runić, Jasmina
PY  - 2016
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/1017
AB  - Iron and sulfur oxidizing chemolithoautotrophic acidophilic bacteria, such as Acidithiobacillus species, hold the dominant role in mine environments characterized by low pH values and high concentrations of reduced sulfur and iron compounds, such as ores, rocks and acid drainage waters from mines. On the other hand, heterotrophic microorganisms, especially their biofilms, from these specific niches are receiving increased attention, but their potential eco-physiological roles have not been fully understood. Biofilms are considered a threat to human health, but biofilms also have beneficial properties as they are deployed in waste recycling and bioremediation systems. We have analyzed interactions of the metal tolerant heterotrophic microorganisms in biofilms with iron oxidizing autotrophic bacteria both from the sulphidic mine environment (copper mine Bor, Serbia). High tolerance to Cu2+, Cd2+ and Cr6+ and the presence of genetic determinants for the respective metal tolerance and biofilm-forming ability was shown for indigenous heterotrophic bacteria that included strains of Staphylococcus and Rhodococcus. Two well characterized bacteria-Pseudomonas aeruginosa PAO1 (known biofilm former) and Cupriavidus metallidurans CH34 (known metal resistant representative) were also included in the study. The interaction and survivability of autotrophic iron oxidizing Acidithiobacillus bacteria and biofilms of heterotrophic bacteria during co-cultivation was revealed. Finally, the effect of heterotrophic biofilms on bioleaching process with indigenous iron oxidizing Acidithiobacillus species was shown not to be inhibitory under in vitro conditions. (C) 2016 Elsevier Ltd. All rights reserved.
PB  - Elsevier
T2  - Journal of Environmental Management
T1  - Interactions of the metal tolerant heterotrophic microorganisms and iron oxidizing autotrophic bacteria from sulphidic mine environment during bioleaching experiments
VL  - 172
SP  - 151
EP  - 161
DO  - 10.1016/j.jenvman.2016.02.041
ER  - 

@article{
author = "Jeremić, Sanja and Beškoski, Vladimir P. and Đokić, Lidija and Vasiljević, Branka and Vrvić, Miroslav M. and Avdalović, Jelena and Gojgić-Cvijović, Gordana and Slavković-Beškoski, Latinka J. and Nikodinović-Runić, Jasmina",
year = "2016",
abstract = "Iron and sulfur oxidizing chemolithoautotrophic acidophilic bacteria, such as Acidithiobacillus species, hold the dominant role in mine environments characterized by low pH values and high concentrations of reduced sulfur and iron compounds, such as ores, rocks and acid drainage waters from mines. On the other hand, heterotrophic microorganisms, especially their biofilms, from these specific niches are receiving increased attention, but their potential eco-physiological roles have not been fully understood. Biofilms are considered a threat to human health, but biofilms also have beneficial properties as they are deployed in waste recycling and bioremediation systems. We have analyzed interactions of the metal tolerant heterotrophic microorganisms in biofilms with iron oxidizing autotrophic bacteria both from the sulphidic mine environment (copper mine Bor, Serbia). High tolerance to Cu2+, Cd2+ and Cr6+ and the presence of genetic determinants for the respective metal tolerance and biofilm-forming ability was shown for indigenous heterotrophic bacteria that included strains of Staphylococcus and Rhodococcus. Two well characterized bacteria-Pseudomonas aeruginosa PAO1 (known biofilm former) and Cupriavidus metallidurans CH34 (known metal resistant representative) were also included in the study. The interaction and survivability of autotrophic iron oxidizing Acidithiobacillus bacteria and biofilms of heterotrophic bacteria during co-cultivation was revealed. Finally, the effect of heterotrophic biofilms on bioleaching process with indigenous iron oxidizing Acidithiobacillus species was shown not to be inhibitory under in vitro conditions. (C) 2016 Elsevier Ltd. All rights reserved.",
publisher = "Elsevier",
journal = "Journal of Environmental Management",
title = "Interactions of the metal tolerant heterotrophic microorganisms and iron oxidizing autotrophic bacteria from sulphidic mine environment during bioleaching experiments",
volume = "172",
pages = "151-161",
doi = "10.1016/j.jenvman.2016.02.041"
}

Jeremić, S., Beškoski, V. P., Đokić, L., Vasiljević, B., Vrvić, M. M., Avdalović, J., Gojgić-Cvijović, G., Slavković-Beškoski, L. J.,& Nikodinović-Runić, J.. (2016). Interactions of the metal tolerant heterotrophic microorganisms and iron oxidizing autotrophic bacteria from sulphidic mine environment during bioleaching experiments. in Journal of Environmental Management
Elsevier., 172, 151-161.
https://doi.org/10.1016/j.jenvman.2016.02.041

Jeremić S, Beškoski VP, Đokić L, Vasiljević B, Vrvić MM, Avdalović J, Gojgić-Cvijović G, Slavković-Beškoski LJ, Nikodinović-Runić J. Interactions of the metal tolerant heterotrophic microorganisms and iron oxidizing autotrophic bacteria from sulphidic mine environment during bioleaching experiments. in Journal of Environmental Management. 2016;172:151-161.
doi:10.1016/j.jenvman.2016.02.041 .

Jeremić, Sanja, Beškoski, Vladimir P., Đokić, Lidija, Vasiljević, Branka, Vrvić, Miroslav M., Avdalović, Jelena, Gojgić-Cvijović, Gordana, Slavković-Beškoski, Latinka J., Nikodinović-Runić, Jasmina, "Interactions of the metal tolerant heterotrophic microorganisms and iron oxidizing autotrophic bacteria from sulphidic mine environment during bioleaching experiments" in Journal of Environmental Management, 172 (2016):151-161,
https://doi.org/10.1016/j.jenvman.2016.02.041 . .

TY  - CONF
AU  - Kekez, Branka
AU  - Gojgić-Cvijović, Gordana
AU  - Jakovljević, Dragica
AU  - Živković, Ljiljana
AU  - Beškoski, Vladimir P.
AU  - Vrvić, Miroslav
PY  - 2014
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9237
AB  - In this work, gold nanoparticles (AuNPs) were synthesized in aqueous
solution by aldehyde functionalized microbial polysaccharide levan as a
reducing agent. Resulting nanoparticles were characterized by UV-Vis
spectroscopy and by particle size analysis.
PB  - Society of Physical Chemists of Serbia
C3  - Physical chemistry 2014: 12th International Conference on Fundamental and Applied Aspects of Physical Chemistry
T1  - Synthesis of gold nanoparticles using aldehyde functionalized levan as reducing agent
VL  - H-24-P
UR  - https://hdl.handle.net/21.15107/rcub_vinar_9237
ER  - 

@conference{
author = "Kekez, Branka and Gojgić-Cvijović, Gordana and Jakovljević, Dragica and Živković, Ljiljana and Beškoski, Vladimir P. and Vrvić, Miroslav",
year = "2014",
abstract = "In this work, gold nanoparticles (AuNPs) were synthesized in aqueous
solution by aldehyde functionalized microbial polysaccharide levan as a
reducing agent. Resulting nanoparticles were characterized by UV-Vis
spectroscopy and by particle size analysis.",
publisher = "Society of Physical Chemists of Serbia",
journal = "Physical chemistry 2014: 12th International Conference on Fundamental and Applied Aspects of Physical Chemistry",
title = "Synthesis of gold nanoparticles using aldehyde functionalized levan as reducing agent",
volume = "H-24-P",
url = "https://hdl.handle.net/21.15107/rcub_vinar_9237"
}

Kekez, B., Gojgić-Cvijović, G., Jakovljević, D., Živković, L., Beškoski, V. P.,& Vrvić, M.. (2014). Synthesis of gold nanoparticles using aldehyde functionalized levan as reducing agent. in Physical chemistry 2014: 12th International Conference on Fundamental and Applied Aspects of Physical Chemistry
Society of Physical Chemists of Serbia., H-24-P.
https://hdl.handle.net/21.15107/rcub_vinar_9237

Kekez B, Gojgić-Cvijović G, Jakovljević D, Živković L, Beškoski VP, Vrvić M. Synthesis of gold nanoparticles using aldehyde functionalized levan as reducing agent. in Physical chemistry 2014: 12th International Conference on Fundamental and Applied Aspects of Physical Chemistry. 2014;H-24-P.
https://hdl.handle.net/21.15107/rcub_vinar_9237 .

Kekez, Branka, Gojgić-Cvijović, Gordana, Jakovljević, Dragica, Živković, Ljiljana, Beškoski, Vladimir P., Vrvić, Miroslav, "Synthesis of gold nanoparticles using aldehyde functionalized levan as reducing agent" in Physical chemistry 2014: 12th International Conference on Fundamental and Applied Aspects of Physical Chemistry, H-24-P (2014),
https://hdl.handle.net/21.15107/rcub_vinar_9237 .

TY  - JOUR
AU  - Beškoski, Vladimir P.
AU  - Takemine, Shusuke
AU  - Nakano, Takeshi
AU  - Slavković-Beškoski, Latinka J.
AU  - Gojgić-Cvijović, Gordana
AU  - Ilić, Mila
AU  - Miletic, Srdjan
AU  - Vrvić, Miroslav M.
PY  - 2013
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/5512
AB  - Perfluoroalkyl sulfonates (PFSAs) and perfluoroalkyl carboxylates (PFCAs) were analyzed in sediment samples from the wastewater canal draining the industrial complex of Pancevo, Serbia (oil refinery, petrochemical plant, and fertilizer factory). The canal is directly connected to Europes second largest river, the Danube, which drains its water into the Black Sea. Perfluorooctane sulfonate (PFOS) up to 5.7 ng d(-1) weight (dw) and total Perfluorinated compounds (PFCs) up to 6.3 ng g(-1) dw were detected. Compared to other reports, high levels of PFOS were found, even though PFCs are not used in the industrial production associated with this canal. The PFOS concentration in water was recalculated using the adsorption coefficient, K-oc from literature. Using the average output of wastewater from the canal, a mass load of 1.38 kg PFOS per year discharged in the Danube River has been calculated, which undoubtedly points to the contribution to global persistent organic pollution of surface waters originating from this industrial place. (C) 2013 Elsevier Ltd. All rights reserved.
T2  - Chemosphere
T1  - Perfluorinated compounds in sediment samples from the wastewater canal of Pancevo (Serbia) industrial area
VL  - 91
IS  - 10
SP  - 1408
EP  - 1415
DO  - 10.1016/j.chemosphere.2012.12.079
ER  - 

@article{
author = "Beškoski, Vladimir P. and Takemine, Shusuke and Nakano, Takeshi and Slavković-Beškoski, Latinka J. and Gojgić-Cvijović, Gordana and Ilić, Mila and Miletic, Srdjan and Vrvić, Miroslav M.",
year = "2013",
abstract = "Perfluoroalkyl sulfonates (PFSAs) and perfluoroalkyl carboxylates (PFCAs) were analyzed in sediment samples from the wastewater canal draining the industrial complex of Pancevo, Serbia (oil refinery, petrochemical plant, and fertilizer factory). The canal is directly connected to Europes second largest river, the Danube, which drains its water into the Black Sea. Perfluorooctane sulfonate (PFOS) up to 5.7 ng d(-1) weight (dw) and total Perfluorinated compounds (PFCs) up to 6.3 ng g(-1) dw were detected. Compared to other reports, high levels of PFOS were found, even though PFCs are not used in the industrial production associated with this canal. The PFOS concentration in water was recalculated using the adsorption coefficient, K-oc from literature. Using the average output of wastewater from the canal, a mass load of 1.38 kg PFOS per year discharged in the Danube River has been calculated, which undoubtedly points to the contribution to global persistent organic pollution of surface waters originating from this industrial place. (C) 2013 Elsevier Ltd. All rights reserved.",
journal = "Chemosphere",
title = "Perfluorinated compounds in sediment samples from the wastewater canal of Pancevo (Serbia) industrial area",
volume = "91",
number = "10",
pages = "1408-1415",
doi = "10.1016/j.chemosphere.2012.12.079"
}

Beškoski, V. P., Takemine, S., Nakano, T., Slavković-Beškoski, L. J., Gojgić-Cvijović, G., Ilić, M., Miletic, S.,& Vrvić, M. M.. (2013). Perfluorinated compounds in sediment samples from the wastewater canal of Pancevo (Serbia) industrial area. in Chemosphere, 91(10), 1408-1415.
https://doi.org/10.1016/j.chemosphere.2012.12.079

Beškoski VP, Takemine S, Nakano T, Slavković-Beškoski LJ, Gojgić-Cvijović G, Ilić M, Miletic S, Vrvić MM. Perfluorinated compounds in sediment samples from the wastewater canal of Pancevo (Serbia) industrial area. in Chemosphere. 2013;91(10):1408-1415.
doi:10.1016/j.chemosphere.2012.12.079 .

Beškoski, Vladimir P., Takemine, Shusuke, Nakano, Takeshi, Slavković-Beškoski, Latinka J., Gojgić-Cvijović, Gordana, Ilić, Mila, Miletic, Srdjan, Vrvić, Miroslav M., "Perfluorinated compounds in sediment samples from the wastewater canal of Pancevo (Serbia) industrial area" in Chemosphere, 91, no. 10 (2013):1408-1415,
https://doi.org/10.1016/j.chemosphere.2012.12.079 . .

TY  - JOUR
AU  - Krinulović, Katarina
AU  - Bugarčić, Živadin D.
AU  - Vrvić, Miroslav M.
AU  - Krstić, Danijela Z.
AU  - Vasić, Vesna M.
PY  - 2006
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3120
AB  - The effect of (mu(3)-diethylentriamino)-chloro-palladium(II)-chloride ([PdCl(dien)]Cl) on the activity of Na/K-ATPase from porcine cerebral cortex was studied in vitro, in the absence and presence of -SH containing ligandS L-cysteine and glutathione (GSH). The aim of the study was to elucidate the mechanism of [PdCl(dien)](+) induced inhibition of the enzyme activity and to examine the ability of thiols to prevent and recover the inhibition. The coordinative interaction between [PdCl(dien)](+) and enzyme was verified by UV and H-1 NMR spectra. The semblance in the changes in absorption spectra of [PdCl(dien)](+) in the presence of Na/K-ATPase and thiols (L-Cysteine and GSH) suggested that the complex ion interacts with enzymatic sulfhydryl groups. [PdCl(dien)](+) inhibited the enzyme activity in a dose-dependent manner. The Hill analysis of the inhibition curve yielded the half-maximum inhibitory activity value, IC50 = 1.21 x 10(-4) M, and Hill coefficient, n = 0.7, suggesting the negative cooperation for binding of [PdCl(dien)](+) to the enzyme. Dependence of the initial reaction rate on the concentration of MgATp(2-) exhibited typical Michelis-Menten kinetics in the absence and presence of the inhibitor. Kinetic analysis showed that [PdCl(dien)](+) inhibited Na/K-ATPase by reducing the maximum reaction rate (V-max), rather than changing the affinity to the substrate (Km). Kinetic parameters derived using Lineweaver-Burk transformation of experimental data indicated the non-competitive nature of Na/K-ATPase inhibition. The inhibitory constant, K-i = 1.05 x 10(-4) M, was determined from secondary replot of Lineweaver-Burk graph, and correlated with stability constants of [Pd(dien)(thiol)] complexes. 1 x 10(-3) M L-Cysteine or GSH prevented the enzyme inhibition induced by Pd(II) complex cation when present below 1 x 10(-4) M. The both thiols completely reversed the inhibited activity in the concentration dependent manner, due to the complex formation with [PdCl(dien)](+). (c) 2006 Elsevier Ltd. All rights reserved.
T2  - Toxicology in Vitro
T1  - Prevention and recovery of (mu(3)-diethylentriamino)-chloro-palladium(II)-chloride induced inhibition of Na/K-ATPase by SH containing ligands - L-cysteine and glutathione
VL  - 20
IS  - 8
SP  - 1292
EP  - 1299
DO  - 10.1016/j.tiv.2006.03.002
ER  - 

@article{
author = "Krinulović, Katarina and Bugarčić, Živadin D. and Vrvić, Miroslav M. and Krstić, Danijela Z. and Vasić, Vesna M.",
year = "2006",
abstract = "The effect of (mu(3)-diethylentriamino)-chloro-palladium(II)-chloride ([PdCl(dien)]Cl) on the activity of Na/K-ATPase from porcine cerebral cortex was studied in vitro, in the absence and presence of -SH containing ligandS L-cysteine and glutathione (GSH). The aim of the study was to elucidate the mechanism of [PdCl(dien)](+) induced inhibition of the enzyme activity and to examine the ability of thiols to prevent and recover the inhibition. The coordinative interaction between [PdCl(dien)](+) and enzyme was verified by UV and H-1 NMR spectra. The semblance in the changes in absorption spectra of [PdCl(dien)](+) in the presence of Na/K-ATPase and thiols (L-Cysteine and GSH) suggested that the complex ion interacts with enzymatic sulfhydryl groups. [PdCl(dien)](+) inhibited the enzyme activity in a dose-dependent manner. The Hill analysis of the inhibition curve yielded the half-maximum inhibitory activity value, IC50 = 1.21 x 10(-4) M, and Hill coefficient, n = 0.7, suggesting the negative cooperation for binding of [PdCl(dien)](+) to the enzyme. Dependence of the initial reaction rate on the concentration of MgATp(2-) exhibited typical Michelis-Menten kinetics in the absence and presence of the inhibitor. Kinetic analysis showed that [PdCl(dien)](+) inhibited Na/K-ATPase by reducing the maximum reaction rate (V-max), rather than changing the affinity to the substrate (Km). Kinetic parameters derived using Lineweaver-Burk transformation of experimental data indicated the non-competitive nature of Na/K-ATPase inhibition. The inhibitory constant, K-i = 1.05 x 10(-4) M, was determined from secondary replot of Lineweaver-Burk graph, and correlated with stability constants of [Pd(dien)(thiol)] complexes. 1 x 10(-3) M L-Cysteine or GSH prevented the enzyme inhibition induced by Pd(II) complex cation when present below 1 x 10(-4) M. The both thiols completely reversed the inhibited activity in the concentration dependent manner, due to the complex formation with [PdCl(dien)](+). (c) 2006 Elsevier Ltd. All rights reserved.",
journal = "Toxicology in Vitro",
title = "Prevention and recovery of (mu(3)-diethylentriamino)-chloro-palladium(II)-chloride induced inhibition of Na/K-ATPase by SH containing ligands - L-cysteine and glutathione",
volume = "20",
number = "8",
pages = "1292-1299",
doi = "10.1016/j.tiv.2006.03.002"
}

Krinulović, K., Bugarčić, Ž. D., Vrvić, M. M., Krstić, D. Z.,& Vasić, V. M.. (2006). Prevention and recovery of (mu(3)-diethylentriamino)-chloro-palladium(II)-chloride induced inhibition of Na/K-ATPase by SH containing ligands - L-cysteine and glutathione. in Toxicology in Vitro, 20(8), 1292-1299.
https://doi.org/10.1016/j.tiv.2006.03.002

Krinulović K, Bugarčić ŽD, Vrvić MM, Krstić DZ, Vasić VM. Prevention and recovery of (mu(3)-diethylentriamino)-chloro-palladium(II)-chloride induced inhibition of Na/K-ATPase by SH containing ligands - L-cysteine and glutathione. in Toxicology in Vitro. 2006;20(8):1292-1299.
doi:10.1016/j.tiv.2006.03.002 .

Krinulović, Katarina, Bugarčić, Živadin D., Vrvić, Miroslav M., Krstić, Danijela Z., Vasić, Vesna M., "Prevention and recovery of (mu(3)-diethylentriamino)-chloro-palladium(II)-chloride induced inhibition of Na/K-ATPase by SH containing ligands - L-cysteine and glutathione" in Toxicology in Vitro, 20, no. 8 (2006):1292-1299,
https://doi.org/10.1016/j.tiv.2006.03.002 . .

TY  - JOUR
AU  - Arandjelovic, S
AU  - Tešić, Živoslav
AU  - Juranic, Z
AU  - Radulović, Siniša S.
AU  - Vrvić, Miroslav M.
AU  - Potkonjak, Branislav
AU  - Ilić, Z.
PY  - 2002
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2609
AB  - Purpose of this work was to synthesize several cis-/trans- isomer pairs of the platinum(II) complexes, and study the extent and the mode of their antiproliferative activity on HeLa cells. Six platinum(II) isomer pairs have a general formula cis-/trans-[PtA(2) X-2] where A is ligand: ammonia (NH3), pyridine (Py); and X is ligand: chloride ion (Cl-), bromide ion (Br-), iodide ion (I-), thiocyanato, ion (SCN-); four compounds have different structural formulas, and these are cis-/trans-[Pt(NH2OH)(2) (NH3)(2)]Cl-2, and cis-/trans- Pt(Gly)(2), where Gly is bidentate glycinato ligand. Results of the MTT assay, showed that six cis- and one trans-platinum(II) complexes exhibited cytotoxicity (IC50) ranging between 5 and 33 muM. Most of the cis-platinum(II) isomers caused significant alteration of cell cycle phases progression, and induced apoptosis in degree that varied among different compounds, as evaluated using flowcytometry and morphological study. Spectrophotometric analysis (AAS) indicated that there is no correlation between intracellular platinum(II) accumulation and cytotoxicity of tested complexes.
T2  - Journal of Experimental and Clinical Cancer Research
T1  - Antiproliferative activity of some cis-/trans-platinum(II) complexes on HeLa cells
VL  - 21
IS  - 4
SP  - 519
EP  - 526
UR  - https://hdl.handle.net/21.15107/rcub_vinar_2609
ER  - 

@article{
author = "Arandjelovic, S and Tešić, Živoslav and Juranic, Z and Radulović, Siniša S. and Vrvić, Miroslav M. and Potkonjak, Branislav and Ilić, Z.",
year = "2002",
abstract = "Purpose of this work was to synthesize several cis-/trans- isomer pairs of the platinum(II) complexes, and study the extent and the mode of their antiproliferative activity on HeLa cells. Six platinum(II) isomer pairs have a general formula cis-/trans-[PtA(2) X-2] where A is ligand: ammonia (NH3), pyridine (Py); and X is ligand: chloride ion (Cl-), bromide ion (Br-), iodide ion (I-), thiocyanato, ion (SCN-); four compounds have different structural formulas, and these are cis-/trans-[Pt(NH2OH)(2) (NH3)(2)]Cl-2, and cis-/trans- Pt(Gly)(2), where Gly is bidentate glycinato ligand. Results of the MTT assay, showed that six cis- and one trans-platinum(II) complexes exhibited cytotoxicity (IC50) ranging between 5 and 33 muM. Most of the cis-platinum(II) isomers caused significant alteration of cell cycle phases progression, and induced apoptosis in degree that varied among different compounds, as evaluated using flowcytometry and morphological study. Spectrophotometric analysis (AAS) indicated that there is no correlation between intracellular platinum(II) accumulation and cytotoxicity of tested complexes.",
journal = "Journal of Experimental and Clinical Cancer Research",
title = "Antiproliferative activity of some cis-/trans-platinum(II) complexes on HeLa cells",
volume = "21",
number = "4",
pages = "519-526",
url = "https://hdl.handle.net/21.15107/rcub_vinar_2609"
}

Arandjelovic, S., Tešić, Ž., Juranic, Z., Radulović, S. S., Vrvić, M. M., Potkonjak, B.,& Ilić, Z.. (2002). Antiproliferative activity of some cis-/trans-platinum(II) complexes on HeLa cells. in Journal of Experimental and Clinical Cancer Research, 21(4), 519-526.
https://hdl.handle.net/21.15107/rcub_vinar_2609

Arandjelovic S, Tešić Ž, Juranic Z, Radulović SS, Vrvić MM, Potkonjak B, Ilić Z. Antiproliferative activity of some cis-/trans-platinum(II) complexes on HeLa cells. in Journal of Experimental and Clinical Cancer Research. 2002;21(4):519-526.
https://hdl.handle.net/21.15107/rcub_vinar_2609 .

Arandjelovic, S, Tešić, Živoslav, Juranic, Z, Radulović, Siniša S., Vrvić, Miroslav M., Potkonjak, Branislav, Ilić, Z., "Antiproliferative activity of some cis-/trans-platinum(II) complexes on HeLa cells" in Journal of Experimental and Clinical Cancer Research, 21, no. 4 (2002):519-526,
https://hdl.handle.net/21.15107/rcub_vinar_2609 .