TY  - JOUR
AU  - Baroud, Afya A.
AU  - Mihajlović-Lalić, Ljiljana E.
AU  - Stanković, Dalibor M.
AU  - Kajzerberger, Marijana
AU  - Van Hecke, Kristof
AU  - Grgurić-Šipka, Sanja
AU  - Savić, Aleksandar
PY  - 2017
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/1569
AB  - A new Ru(II) bipyridyl complex with O-4-hydrogenpyridine-2,4-dicarboxylate was synthesized and characterized by IR, NMR and mass spectrometry, X-ray diffraction analysis and elemental analysis. The electrochemical characteristics of the complex were investigated by cyclic voltammetry, revealing Ru(II)/Ru(III) electron transfer in the positive range of potentials. On the opposite potential side, multiple partially reversible peaks were dominant, representing subsequent reductions of the bulky bipyridyl moiety. The cytotoxic activity of the complex was tested in two human cancer cell lines: A549 (lung cancer) and K562 (leukemia) as well as non-tumor MRC-5 cells, by MTT assays. The IC50 values were GT 300 and 177.63+/-2.28 mu M for the A549 and K562 cells, respectively.
T2  - Journal of the Serbian Chemical Society
T1  - New ruthenium(II) bipyridyl complex: Synthesis, crystal structure and cytotoxicity
VL  - 82
IS  - 3
SP  - 267
EP  - 275
DO  - 10.2298/JSC170109025B
ER  - 

@article{
author = "Baroud, Afya A. and Mihajlović-Lalić, Ljiljana E. and Stanković, Dalibor M. and Kajzerberger, Marijana and Van Hecke, Kristof and Grgurić-Šipka, Sanja and Savić, Aleksandar",
year = "2017",
abstract = "A new Ru(II) bipyridyl complex with O-4-hydrogenpyridine-2,4-dicarboxylate was synthesized and characterized by IR, NMR and mass spectrometry, X-ray diffraction analysis and elemental analysis. The electrochemical characteristics of the complex were investigated by cyclic voltammetry, revealing Ru(II)/Ru(III) electron transfer in the positive range of potentials. On the opposite potential side, multiple partially reversible peaks were dominant, representing subsequent reductions of the bulky bipyridyl moiety. The cytotoxic activity of the complex was tested in two human cancer cell lines: A549 (lung cancer) and K562 (leukemia) as well as non-tumor MRC-5 cells, by MTT assays. The IC50 values were GT 300 and 177.63+/-2.28 mu M for the A549 and K562 cells, respectively.",
journal = "Journal of the Serbian Chemical Society",
title = "New ruthenium(II) bipyridyl complex: Synthesis, crystal structure and cytotoxicity",
volume = "82",
number = "3",
pages = "267-275",
doi = "10.2298/JSC170109025B"
}

Baroud, A. A., Mihajlović-Lalić, L. E., Stanković, D. M., Kajzerberger, M., Van Hecke, K., Grgurić-Šipka, S.,& Savić, A.. (2017). New ruthenium(II) bipyridyl complex: Synthesis, crystal structure and cytotoxicity. in Journal of the Serbian Chemical Society, 82(3), 267-275.
https://doi.org/10.2298/JSC170109025B

Baroud AA, Mihajlović-Lalić LE, Stanković DM, Kajzerberger M, Van Hecke K, Grgurić-Šipka S, Savić A. New ruthenium(II) bipyridyl complex: Synthesis, crystal structure and cytotoxicity. in Journal of the Serbian Chemical Society. 2017;82(3):267-275.
doi:10.2298/JSC170109025B .

Baroud, Afya A., Mihajlović-Lalić, Ljiljana E., Stanković, Dalibor M., Kajzerberger, Marijana, Van Hecke, Kristof, Grgurić-Šipka, Sanja, Savić, Aleksandar, "New ruthenium(II) bipyridyl complex: Synthesis, crystal structure and cytotoxicity" in Journal of the Serbian Chemical Society, 82, no. 3 (2017):267-275,
https://doi.org/10.2298/JSC170109025B . .