TY  - JOUR
AU  - Prokic, B. B.
AU  - Bačić, Goran
AU  - Prokic, B.
AU  - Kalijadis, Ana
AU  - Todorović, Vera
AU  - Puškaš, Nela
AU  - Vidojevic, D.
AU  - Laušević, Mila D.
AU  - Laušević, Zoran
PY  - 2012
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/5251
AB  - In modern medicine implants are very important and so is their design and choice of materials. Almost equally important is the choice of imaging technique used to in vivo monitor their fate and biocompatibility. The aim of this study was to evaluate the ability of magnetic resonance imaging (MRI) in monitoring the biocompatibility of two newly designed carbon fibers. We have analyzed the interaction of surface functionalized carbon fibers (basic and acidic) with muscle and subcutaneous tissues of rabbits. MRI techniques showed to be useful in longitudinal monitoring of the surrounding tissues, assessment of biocompatibility of new implants, and in the distinction of in vivo surgical edema from inflammation. Histopathology confirmed MRI results, thus showing that MRI has a great potential for in vivo studies of such materials.
T2  - Acta Veterinaria, Beograd
T1  - In Vivo Mri Biocompatibility Evaluation of Functionalized Carbon Fibers in Reaction with Soft Tissues
VL  - 62
IS  - 5-6
SP  - 683
EP  - 696
DO  - 10.2298/AVB1206683P
ER  - 

@article{
author = "Prokic, B. B. and Bačić, Goran and Prokic, B. and Kalijadis, Ana and Todorović, Vera and Puškaš, Nela and Vidojevic, D. and Laušević, Mila D. and Laušević, Zoran",
year = "2012",
abstract = "In modern medicine implants are very important and so is their design and choice of materials. Almost equally important is the choice of imaging technique used to in vivo monitor their fate and biocompatibility. The aim of this study was to evaluate the ability of magnetic resonance imaging (MRI) in monitoring the biocompatibility of two newly designed carbon fibers. We have analyzed the interaction of surface functionalized carbon fibers (basic and acidic) with muscle and subcutaneous tissues of rabbits. MRI techniques showed to be useful in longitudinal monitoring of the surrounding tissues, assessment of biocompatibility of new implants, and in the distinction of in vivo surgical edema from inflammation. Histopathology confirmed MRI results, thus showing that MRI has a great potential for in vivo studies of such materials.",
journal = "Acta Veterinaria, Beograd",
title = "In Vivo Mri Biocompatibility Evaluation of Functionalized Carbon Fibers in Reaction with Soft Tissues",
volume = "62",
number = "5-6",
pages = "683-696",
doi = "10.2298/AVB1206683P"
}

Prokic, B. B., Bačić, G., Prokic, B., Kalijadis, A., Todorović, V., Puškaš, N., Vidojevic, D., Laušević, M. D.,& Laušević, Z.. (2012). In Vivo Mri Biocompatibility Evaluation of Functionalized Carbon Fibers in Reaction with Soft Tissues. in Acta Veterinaria, Beograd, 62(5-6), 683-696.
https://doi.org/10.2298/AVB1206683P

Prokic BB, Bačić G, Prokic B, Kalijadis A, Todorović V, Puškaš N, Vidojevic D, Laušević MD, Laušević Z. In Vivo Mri Biocompatibility Evaluation of Functionalized Carbon Fibers in Reaction with Soft Tissues. in Acta Veterinaria, Beograd. 2012;62(5-6):683-696.
doi:10.2298/AVB1206683P .

Prokic, B. B., Bačić, Goran, Prokic, B., Kalijadis, Ana, Todorović, Vera, Puškaš, Nela, Vidojevic, D., Laušević, Mila D., Laušević, Zoran, "In Vivo Mri Biocompatibility Evaluation of Functionalized Carbon Fibers in Reaction with Soft Tissues" in Acta Veterinaria, Beograd, 62, no. 5-6 (2012):683-696,
https://doi.org/10.2298/AVB1206683P . .

TY  - JOUR
AU  - Đikić, Dragoslava
AU  - Budec, Mirela
AU  - Vranješ-Đurić, Sanja
AU  - Todorović, Vera
AU  - Drndarević, Neda C.
AU  - Vignjevic, Sanja
AU  - Mitrovic, Olivera
PY  - 2012
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/5130
AB  - Background: This study was performed to investigate expression and distribution of glucocorticoid receptor (GR) in the rat adrenal cortex, acute effect of ethanol on its expression and possible role of endogenous nitric oxide (NO) in this phenomenon. Methods: Adult female Wistar rats showing diestrus day 1 were treated with: a) ethanol (2 or 4 g/kg body weight (b.w.), ip), b) N-omega-nitro-L-arginine methyl ester (L-NAME), well-known competitive inhibitor of all isoforms of NO synthase (NOS), (30 mg/kg b.w., sc) followed by ethanol (4 g/kg, ip) 3 h later and c) L-NAME (30 mg/kg b.w., sc) followed by saline (ip) 3 h later. Untreated rats were used as controls. Adrenocortical expression of GR was estimated by immunohistochemistry. Results: Strong nuclear GR staining was observed throughout the cortex of control rats. Acute ethanol treatment significantly decreased the expression of GR in the zona fasciculata and zona reticularis. Blockade of NO formation had no influence on this effect of ethanol, whereas L-NAME itself induced significant decline in GR immunoreactivity. Conclusions: Obtained findings are the first to demonstrate localization and distribution of the GR throughout the rat adrenal cortex and to suggest that ethanol as well as endogenous NO may modulate adrenocortical expression of this steroid receptor.
T2  - Pharmacological Reports
T1  - Ethanol and nitric oxide modulate expression of glucocorticoid receptor in the rat adrenal cortex
VL  - 64
IS  - 4
SP  - 896
EP  - 901
DO  - 10.1016/S1734-1140(12)70884-8
ER  - 

@article{
author = "Đikić, Dragoslava and Budec, Mirela and Vranješ-Đurić, Sanja and Todorović, Vera and Drndarević, Neda C. and Vignjevic, Sanja and Mitrovic, Olivera",
year = "2012",
abstract = "Background: This study was performed to investigate expression and distribution of glucocorticoid receptor (GR) in the rat adrenal cortex, acute effect of ethanol on its expression and possible role of endogenous nitric oxide (NO) in this phenomenon. Methods: Adult female Wistar rats showing diestrus day 1 were treated with: a) ethanol (2 or 4 g/kg body weight (b.w.), ip), b) N-omega-nitro-L-arginine methyl ester (L-NAME), well-known competitive inhibitor of all isoforms of NO synthase (NOS), (30 mg/kg b.w., sc) followed by ethanol (4 g/kg, ip) 3 h later and c) L-NAME (30 mg/kg b.w., sc) followed by saline (ip) 3 h later. Untreated rats were used as controls. Adrenocortical expression of GR was estimated by immunohistochemistry. Results: Strong nuclear GR staining was observed throughout the cortex of control rats. Acute ethanol treatment significantly decreased the expression of GR in the zona fasciculata and zona reticularis. Blockade of NO formation had no influence on this effect of ethanol, whereas L-NAME itself induced significant decline in GR immunoreactivity. Conclusions: Obtained findings are the first to demonstrate localization and distribution of the GR throughout the rat adrenal cortex and to suggest that ethanol as well as endogenous NO may modulate adrenocortical expression of this steroid receptor.",
journal = "Pharmacological Reports",
title = "Ethanol and nitric oxide modulate expression of glucocorticoid receptor in the rat adrenal cortex",
volume = "64",
number = "4",
pages = "896-901",
doi = "10.1016/S1734-1140(12)70884-8"
}

Đikić, D., Budec, M., Vranješ-Đurić, S., Todorović, V., Drndarević, N. C., Vignjevic, S.,& Mitrovic, O.. (2012). Ethanol and nitric oxide modulate expression of glucocorticoid receptor in the rat adrenal cortex. in Pharmacological Reports, 64(4), 896-901.
https://doi.org/10.1016/S1734-1140(12)70884-8

Đikić D, Budec M, Vranješ-Đurić S, Todorović V, Drndarević NC, Vignjevic S, Mitrovic O. Ethanol and nitric oxide modulate expression of glucocorticoid receptor in the rat adrenal cortex. in Pharmacological Reports. 2012;64(4):896-901.
doi:10.1016/S1734-1140(12)70884-8 .

Đikić, Dragoslava, Budec, Mirela, Vranješ-Đurić, Sanja, Todorović, Vera, Drndarević, Neda C., Vignjevic, Sanja, Mitrovic, Olivera, "Ethanol and nitric oxide modulate expression of glucocorticoid receptor in the rat adrenal cortex" in Pharmacological Reports, 64, no. 4 (2012):896-901,
https://doi.org/10.1016/S1734-1140(12)70884-8 . .