TY  - JOUR
AU  - Đačanin-Far, Ljubica
AU  - Dramićanin, Tatjana
AU  - Medić, Mina
AU  - Ristić, Zoran
AU  - Periša, Jovana
AU  - Đorđević, Vesna
AU  - Antić, Željka
AU  - Dramićanin, Miroslav
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12568
AB  - Herein, we demonstrate the photoluminescence properties of Dy3+-activated YNbO4, LuNbO4, and mixed YxLu1−xNbO4:Dy3+ (x=0.25, 0.5, 0.75) phosphors. For this purpose, fve samples with a fxed Dy3+ concentration (2 mol%) were prepared by the solid-state reaction method. X-ray difraction measurements showed that all phosphors crystallize in a monoclinic fergusonite-beta-(Y) structure with a C2/c space group. Scanning electron microscopy clearly shows that samples are composed of dense, well-developed micron-sized, cube-shaped grains with rounded edges. The photoluminescent emission spectra feature Dy3+ peaks at standard positions corresponding to transitions from the 4 F9/2 excited emitting level to the 6 HJ (J=15/2; 13/2; 11/2 and 9/2) lower levels with two dominant emission bands placed in the blue (~479 nm, B) and yellow (~576 nm, Y) spectral region. It is observed that with Lu increase in the host lattice Y/B ratio decreases toward the desired ratio of unity to obtain white light. To evaluate the suitability of these phosphors for use in solid-state lighting, their photoluminescence emission was analyzed in detail by calculating CIE coordinates, correlated color temperature (CCT) and Delta u,v (DUV). It is shown that CIE chromaticity coordinates of all Dy3+-activated YxLu1−xNbO4 samples (x=0, 0.25, 0.5, 0.75, and 1) fall into the white portion of the diagram and that with the increase of Lu in the host lattice color becomes whiter. CCT values for all samples are in the cooler 4000–4500 K range with positive DUVs indicating that color points are placed above the black body curve. The average lifetime of 4 F9/2 level is calculated to be~0.2 ms for all Dy3+-activated YxLu1−xNbO4 samples, indicating that there is no infuence of the Y-to-Lu ratio in the host niobate material on the luminescence kinetics.
T2  - Applied Physics A
T1  - Emission color tunability of dysprosium-activated YNbO4–LuNbO4-mixed phosphors
VL  - 130
IS  - 2
SP  - 107
DO  - 10.1007/s00339-023-07271-z
ER  - 

@article{
author = "Đačanin-Far, Ljubica and Dramićanin, Tatjana and Medić, Mina and Ristić, Zoran and Periša, Jovana and Đorđević, Vesna and Antić, Željka and Dramićanin, Miroslav",
year = "2024",
abstract = "Herein, we demonstrate the photoluminescence properties of Dy3+-activated YNbO4, LuNbO4, and mixed YxLu1−xNbO4:Dy3+ (x=0.25, 0.5, 0.75) phosphors. For this purpose, fve samples with a fxed Dy3+ concentration (2 mol%) were prepared by the solid-state reaction method. X-ray difraction measurements showed that all phosphors crystallize in a monoclinic fergusonite-beta-(Y) structure with a C2/c space group. Scanning electron microscopy clearly shows that samples are composed of dense, well-developed micron-sized, cube-shaped grains with rounded edges. The photoluminescent emission spectra feature Dy3+ peaks at standard positions corresponding to transitions from the 4 F9/2 excited emitting level to the 6 HJ (J=15/2; 13/2; 11/2 and 9/2) lower levels with two dominant emission bands placed in the blue (~479 nm, B) and yellow (~576 nm, Y) spectral region. It is observed that with Lu increase in the host lattice Y/B ratio decreases toward the desired ratio of unity to obtain white light. To evaluate the suitability of these phosphors for use in solid-state lighting, their photoluminescence emission was analyzed in detail by calculating CIE coordinates, correlated color temperature (CCT) and Delta u,v (DUV). It is shown that CIE chromaticity coordinates of all Dy3+-activated YxLu1−xNbO4 samples (x=0, 0.25, 0.5, 0.75, and 1) fall into the white portion of the diagram and that with the increase of Lu in the host lattice color becomes whiter. CCT values for all samples are in the cooler 4000–4500 K range with positive DUVs indicating that color points are placed above the black body curve. The average lifetime of 4 F9/2 level is calculated to be~0.2 ms for all Dy3+-activated YxLu1−xNbO4 samples, indicating that there is no infuence of the Y-to-Lu ratio in the host niobate material on the luminescence kinetics.",
journal = "Applied Physics A",
title = "Emission color tunability of dysprosium-activated YNbO4–LuNbO4-mixed phosphors",
volume = "130",
number = "2",
pages = "107",
doi = "10.1007/s00339-023-07271-z"
}

Đačanin-Far, L., Dramićanin, T., Medić, M., Ristić, Z., Periša, J., Đorđević, V., Antić, Ž.,& Dramićanin, M.. (2024). Emission color tunability of dysprosium-activated YNbO4–LuNbO4-mixed phosphors. in Applied Physics A, 130(2), 107.
https://doi.org/10.1007/s00339-023-07271-z

Đačanin-Far L, Dramićanin T, Medić M, Ristić Z, Periša J, Đorđević V, Antić Ž, Dramićanin M. Emission color tunability of dysprosium-activated YNbO4–LuNbO4-mixed phosphors. in Applied Physics A. 2024;130(2):107.
doi:10.1007/s00339-023-07271-z .

Đačanin-Far, Ljubica, Dramićanin, Tatjana, Medić, Mina, Ristić, Zoran, Periša, Jovana, Đorđević, Vesna, Antić, Željka, Dramićanin, Miroslav, "Emission color tunability of dysprosium-activated YNbO4–LuNbO4-mixed phosphors" in Applied Physics A, 130, no. 2 (2024):107,
https://doi.org/10.1007/s00339-023-07271-z . .

TY  - JOUR
AU  - Tanić, Nikola
AU  - Dramićanin, Tatjana
AU  - Ademović, Nejla
AU  - Tomić, Tijana
AU  - Murganić, Blagoje
AU  - Milovanović, Zorka
AU  - Nedeljković, Milica
AU  - Tanić, Nasta
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12956
AB  - Rak dojke (RD) je najčešći tip maligniteta i vodeći uzrok smrti od raka kod žena širom sveta. RD je izuzetno heterogena bolest i stoga su neophodni različiti modaliteti lečenja da bi se pokrile ove razlike. Cilj našeg istraživanja je bio da se ispita uticaj inaktivacije TP53 i PTEN tumor supresorskih gena (TSG) na odgovor RD na različite modalitete lečenja, kao i njihova moguća saradnja u tome, na postoperativnim uzorcima RD. Metode. Pacijentkinje su klasifikovane, na osnovu primenjene adjuvantne terapije, u četiri različite grupe: one koje su primale samo hormonsku terapiju (HT), hormonsku terapiju u kombinaciji sa hemoterapijom (HT/CHT), hormonsku terapiju u kombinaciji sa hemoterapijom i biološkom terapijom (HT/CHT/H) i druge sistemske terapije koje isključuju HT. Funkcionalna inaktivacija TP53 i PTEN TSG je proučavana analizom mutacionog statusa, gubitka heterozigotnosti (LOH) i metilacionog statusa. Rezultati. Naši rezultati su pokazali da je TP53 gen izmenjen kod 63 od 90 pacijenata (70%), dok je učestalost promena PTEN gena bila nešto niža, 54 od 90 (60%). Simultana inaktivacija je detektovana u 43 testirana uzorka (48%) sa značajnom povezanošću između dva analizirana TSG-a. Dalje, pokazali smo da status TP53 ima značajan uticaj na odgovor pacijenata na terapiju. Suprotno ovome, nismo pokazali značajnu asocijaciju između mutacionog statusa PTEN-a i različitih modaliteta lečenja. Međutim, utvrđena je značajna povezanost između primenjenih terapija i simultanih inaktivacija ova dva TSG-a (p = 0,00001). Zaključak. Pacijenti sa wtTP53 pokazuju značajno bolji terapijski odgovor bez obzira na vrstu terapije u poređenju sa nosiocima mutiranog TP53 gena.
AB  - Introduction. Breast cancer (BC) is the most frequent type of malignancy and the leading cause of cancer related death among women worldwide. BC is exceptionally heterogeneous disease and therefore distinct treatment modalities are necessary to address these differences. The aim of our study was to investigate the impact of TP53 and PTEN tumor suppressor genes (TSGs) inactivation on BC response to different treatment modalities and their possible cooperation, on post-operative BC samples.   Methods. Patients were classified, based on applied adjuvant therapy, into four distinct groups: those that received hormonal therapy (HT) only, hormonal therapy combined with chemotherapy (HT/CHT), hormonal therapy combined with chemo and biological therapy (HT/CHT/H), and other systemic therapies that exclude HT. Functional inactivation of TP53 and PTEN TSG’s were studied by mutation, loss of heterozygosity (LOH) and hypermethylation analysis.   Results. Our results revealed that TP53 gene was altered in 63 out of 90 specimens (70%), while the frequency of PTEN alterations was slightly lower, 54 out of 90 (60%). Simultaneous inactivation was detected in 43 tested samples (48%) with significant association between two analyzed TSGs. Further, we found that TP53 status has significant influence on patients’ therapy response. Contrary to this, no significance was found between mutational status of PTEN and various treatment modalities. However, significant association was found between the type of applied therapy and simultaneous alterations of these two TSGs (p = 0.00001).   Conclusion. Patients with wtTP53 show significantly better therapy response regardless of the type of therapy, compared to carriers of altered TPp53 gene.
T2  - Biomedicinska istraživanja
T1  - The impact of TP53 and PTEN tumor suppressor genes on  response to different breast cancer treatment modalities
T1  - Uticaj tumor supresorskih gena TP53 i PTEN na odgovor na različite načine lečenja raka dojke
VL  - 13
IS  - 2
SP  - 105
EP  - 117
DO  - 10.5937/BII2202105T
ER  - 

@article{
author = "Tanić, Nikola and Dramićanin, Tatjana and Ademović, Nejla and Tomić, Tijana and Murganić, Blagoje and Milovanović, Zorka and Nedeljković, Milica and Tanić, Nasta",
year = "2022",
abstract = "Rak dojke (RD) je najčešći tip maligniteta i vodeći uzrok smrti od raka kod žena širom sveta. RD je izuzetno heterogena bolest i stoga su neophodni različiti modaliteti lečenja da bi se pokrile ove razlike. Cilj našeg istraživanja je bio da se ispita uticaj inaktivacije TP53 i PTEN tumor supresorskih gena (TSG) na odgovor RD na različite modalitete lečenja, kao i njihova moguća saradnja u tome, na postoperativnim uzorcima RD. Metode. Pacijentkinje su klasifikovane, na osnovu primenjene adjuvantne terapije, u četiri različite grupe: one koje su primale samo hormonsku terapiju (HT), hormonsku terapiju u kombinaciji sa hemoterapijom (HT/CHT), hormonsku terapiju u kombinaciji sa hemoterapijom i biološkom terapijom (HT/CHT/H) i druge sistemske terapije koje isključuju HT. Funkcionalna inaktivacija TP53 i PTEN TSG je proučavana analizom mutacionog statusa, gubitka heterozigotnosti (LOH) i metilacionog statusa. Rezultati. Naši rezultati su pokazali da je TP53 gen izmenjen kod 63 od 90 pacijenata (70%), dok je učestalost promena PTEN gena bila nešto niža, 54 od 90 (60%). Simultana inaktivacija je detektovana u 43 testirana uzorka (48%) sa značajnom povezanošću između dva analizirana TSG-a. Dalje, pokazali smo da status TP53 ima značajan uticaj na odgovor pacijenata na terapiju. Suprotno ovome, nismo pokazali značajnu asocijaciju između mutacionog statusa PTEN-a i različitih modaliteta lečenja. Međutim, utvrđena je značajna povezanost između primenjenih terapija i simultanih inaktivacija ova dva TSG-a (p = 0,00001). Zaključak. Pacijenti sa wtTP53 pokazuju značajno bolji terapijski odgovor bez obzira na vrstu terapije u poređenju sa nosiocima mutiranog TP53 gena., Introduction. Breast cancer (BC) is the most frequent type of malignancy and the leading cause of cancer related death among women worldwide. BC is exceptionally heterogeneous disease and therefore distinct treatment modalities are necessary to address these differences. The aim of our study was to investigate the impact of TP53 and PTEN tumor suppressor genes (TSGs) inactivation on BC response to different treatment modalities and their possible cooperation, on post-operative BC samples.   Methods. Patients were classified, based on applied adjuvant therapy, into four distinct groups: those that received hormonal therapy (HT) only, hormonal therapy combined with chemotherapy (HT/CHT), hormonal therapy combined with chemo and biological therapy (HT/CHT/H), and other systemic therapies that exclude HT. Functional inactivation of TP53 and PTEN TSG’s were studied by mutation, loss of heterozygosity (LOH) and hypermethylation analysis.   Results. Our results revealed that TP53 gene was altered in 63 out of 90 specimens (70%), while the frequency of PTEN alterations was slightly lower, 54 out of 90 (60%). Simultaneous inactivation was detected in 43 tested samples (48%) with significant association between two analyzed TSGs. Further, we found that TP53 status has significant influence on patients’ therapy response. Contrary to this, no significance was found between mutational status of PTEN and various treatment modalities. However, significant association was found between the type of applied therapy and simultaneous alterations of these two TSGs (p = 0.00001).   Conclusion. Patients with wtTP53 show significantly better therapy response regardless of the type of therapy, compared to carriers of altered TPp53 gene.",
journal = "Biomedicinska istraživanja",
title = "The impact of TP53 and PTEN tumor suppressor genes on  response to different breast cancer treatment modalities, Uticaj tumor supresorskih gena TP53 i PTEN na odgovor na različite načine lečenja raka dojke",
volume = "13",
number = "2",
pages = "105-117",
doi = "10.5937/BII2202105T"
}

Tanić, N., Dramićanin, T., Ademović, N., Tomić, T., Murganić, B., Milovanović, Z., Nedeljković, M.,& Tanić, N.. (2022). The impact of TP53 and PTEN tumor suppressor genes on  response to different breast cancer treatment modalities. in Biomedicinska istraživanja, 13(2), 105-117.
https://doi.org/10.5937/BII2202105T

Tanić N, Dramićanin T, Ademović N, Tomić T, Murganić B, Milovanović Z, Nedeljković M, Tanić N. The impact of TP53 and PTEN tumor suppressor genes on  response to different breast cancer treatment modalities. in Biomedicinska istraživanja. 2022;13(2):105-117.
doi:10.5937/BII2202105T .

Tanić, Nikola, Dramićanin, Tatjana, Ademović, Nejla, Tomić, Tijana, Murganić, Blagoje, Milovanović, Zorka, Nedeljković, Milica, Tanić, Nasta, "The impact of TP53 and PTEN tumor suppressor genes on  response to different breast cancer treatment modalities" in Biomedicinska istraživanja, 13, no. 2 (2022):105-117,
https://doi.org/10.5937/BII2202105T . .

TY  - JOUR
AU  - Sekulić, Milica
AU  - Dramićanin, Tatjana
AU  - Ćirić, Aleksandar
AU  - Đačanin Far, Ljubica
AU  - Dramićanin, Miroslav
AU  - Đorđević, Vesna R.
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10238
AB  - Eu3+-doped YxLu1−xNbO4 (x = 0, 0.25, 0.5, 0.75, 1) were prepared by the solid-state reaction method. YNbO4:Eu3+ and LuNbO4:Eu3+ crystallize as beta-Fergusonite (SG no. 15) in 1–10 μm diameter particles. Photoluminescence emission spectra show a slight linear variation of emission energies and intensities with the solid-solution composition in terms of Y/Lu content. The energy difference between Stark sublevels of 5D0→7F1 emission increases, while the asymmetry ratio decreases with the composition. From the dispersion relations of pure YNbO4 and LuNbO4, the refractive index values for each concentration and emission wavelength are estimated. The Ω2 Judd–Ofelt parameter shows a linear increase from 6.75 to 7.48 × 10−20 cm2 from x = 0 to 1, respectively, and Ω4 from 2.69 to 2.95 × 10−20 cm2. The lowest non-radiative deexcitation rate was observed with x = 1, and thus LuNbO4:Eu3+ is more efficient phosphor than YNbO4:Eu3+.
T2  - Crystals
T1  - Photoluminescence of the Eu3+-Activated YxLu1−xNbO4 (x = 0, 0.25, 0.5, 0.75, 1) Solid-Solution Phosphors
VL  - 12
IS  - 3
SP  - 427
DO  - 10.3390/cryst12030427
ER  - 

@article{
author = "Sekulić, Milica and Dramićanin, Tatjana and Ćirić, Aleksandar and Đačanin Far, Ljubica and Dramićanin, Miroslav and Đorđević, Vesna R.",
year = "2022",
abstract = "Eu3+-doped YxLu1−xNbO4 (x = 0, 0.25, 0.5, 0.75, 1) were prepared by the solid-state reaction method. YNbO4:Eu3+ and LuNbO4:Eu3+ crystallize as beta-Fergusonite (SG no. 15) in 1–10 μm diameter particles. Photoluminescence emission spectra show a slight linear variation of emission energies and intensities with the solid-solution composition in terms of Y/Lu content. The energy difference between Stark sublevels of 5D0→7F1 emission increases, while the asymmetry ratio decreases with the composition. From the dispersion relations of pure YNbO4 and LuNbO4, the refractive index values for each concentration and emission wavelength are estimated. The Ω2 Judd–Ofelt parameter shows a linear increase from 6.75 to 7.48 × 10−20 cm2 from x = 0 to 1, respectively, and Ω4 from 2.69 to 2.95 × 10−20 cm2. The lowest non-radiative deexcitation rate was observed with x = 1, and thus LuNbO4:Eu3+ is more efficient phosphor than YNbO4:Eu3+.",
journal = "Crystals",
title = "Photoluminescence of the Eu3+-Activated YxLu1−xNbO4 (x = 0, 0.25, 0.5, 0.75, 1) Solid-Solution Phosphors",
volume = "12",
number = "3",
pages = "427",
doi = "10.3390/cryst12030427"
}

Sekulić, M., Dramićanin, T., Ćirić, A., Đačanin Far, L., Dramićanin, M.,& Đorđević, V. R.. (2022). Photoluminescence of the Eu3+-Activated YxLu1−xNbO4 (x = 0, 0.25, 0.5, 0.75, 1) Solid-Solution Phosphors. in Crystals, 12(3), 427.
https://doi.org/10.3390/cryst12030427

Sekulić M, Dramićanin T, Ćirić A, Đačanin Far L, Dramićanin M, Đorđević VR. Photoluminescence of the Eu3+-Activated YxLu1−xNbO4 (x = 0, 0.25, 0.5, 0.75, 1) Solid-Solution Phosphors. in Crystals. 2022;12(3):427.
doi:10.3390/cryst12030427 .

Sekulić, Milica, Dramićanin, Tatjana, Ćirić, Aleksandar, Đačanin Far, Ljubica, Dramićanin, Miroslav, Đorđević, Vesna R., "Photoluminescence of the Eu3+-Activated YxLu1−xNbO4 (x = 0, 0.25, 0.5, 0.75, 1) Solid-Solution Phosphors" in Crystals, 12, no. 3 (2022):427,
https://doi.org/10.3390/cryst12030427 . .

TY  - JOUR
AU  - Đačanin Far, Ljubica
AU  - Ćirić, Aleksandar
AU  - Ristić, Zoran
AU  - Periša, Jovana
AU  - Dramićanin, Tatjana
AU  - Lukić-Petrović, Svetlana R.
AU  - Dramićanin, Miroslav
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10342
AB  - Y3NbO7:xEu3+ powders (x = 0.25, 0.5, 0.75, 2, 3, 5, 10 at%) were synthesized by a two-step vibrational milling, alternating with annealing. All the samples crystallize as fluorite-type structure (space group Fm3‾m), with crystallite size 50–60 nm and show a strong orange/red luminescence with an excited state lifetime around 1.2 ms. Photoluminescence excitation and emission spectra show rapid intensity decline after 3 at% of Eu3+ content, indicating this concentration as critical for the concentration quenching, and we predicted multipolar interaction as the dominant mechanism behind it. Judd–Ofelt intensity parameters (Ω2 = 0.941∙10−20 cm2, Ω4 = 0.277∙10−20 cm2, Ω6 = 0.277∙10−20 cm2) were obtained from the excitation spectrum of Y3NbO7:3 at%Eu3+. The emission of this luminescent powder is characterized by radiative and nonradiative lifetimes of 2.3 ms and 2.4 ms, respectively, and an intrinsic quantum yield of 51.5%.
T2  - Ceramics International
T1  - Photoluminescence of Y3NbO7:Eu3+ powders
DO  - 10.1016/j.ceramint.2022.06.130
ER  - 

@article{
author = "Đačanin Far, Ljubica and Ćirić, Aleksandar and Ristić, Zoran and Periša, Jovana and Dramićanin, Tatjana and Lukić-Petrović, Svetlana R. and Dramićanin, Miroslav",
year = "2022",
abstract = "Y3NbO7:xEu3+ powders (x = 0.25, 0.5, 0.75, 2, 3, 5, 10 at%) were synthesized by a two-step vibrational milling, alternating with annealing. All the samples crystallize as fluorite-type structure (space group Fm3‾m), with crystallite size 50–60 nm and show a strong orange/red luminescence with an excited state lifetime around 1.2 ms. Photoluminescence excitation and emission spectra show rapid intensity decline after 3 at% of Eu3+ content, indicating this concentration as critical for the concentration quenching, and we predicted multipolar interaction as the dominant mechanism behind it. Judd–Ofelt intensity parameters (Ω2 = 0.941∙10−20 cm2, Ω4 = 0.277∙10−20 cm2, Ω6 = 0.277∙10−20 cm2) were obtained from the excitation spectrum of Y3NbO7:3 at%Eu3+. The emission of this luminescent powder is characterized by radiative and nonradiative lifetimes of 2.3 ms and 2.4 ms, respectively, and an intrinsic quantum yield of 51.5%.",
journal = "Ceramics International",
title = "Photoluminescence of Y3NbO7:Eu3+ powders",
doi = "10.1016/j.ceramint.2022.06.130"
}

Đačanin Far, L., Ćirić, A., Ristić, Z., Periša, J., Dramićanin, T., Lukić-Petrović, S. R.,& Dramićanin, M.. (2022). Photoluminescence of Y3NbO7:Eu3+ powders. in Ceramics International.
https://doi.org/10.1016/j.ceramint.2022.06.130

Đačanin Far L, Ćirić A, Ristić Z, Periša J, Dramićanin T, Lukić-Petrović SR, Dramićanin M. Photoluminescence of Y3NbO7:Eu3+ powders. in Ceramics International. 2022;.
doi:10.1016/j.ceramint.2022.06.130 .

Đačanin Far, Ljubica, Ćirić, Aleksandar, Ristić, Zoran, Periša, Jovana, Dramićanin, Tatjana, Lukić-Petrović, Svetlana R., Dramićanin, Miroslav, "Photoluminescence of Y3NbO7:Eu3+ powders" in Ceramics International (2022),
https://doi.org/10.1016/j.ceramint.2022.06.130 . .

TY  - CONF
AU  - Sekulić, Milica
AU  - Đačanin Far, Ljubica
AU  - Dramićanin, Tatjana
AU  - Ćirić, Aleksandar
AU  - Dramićanin, Miroslav
AU  - Đorđević, Vesna
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/11341
AB  - Lanthanide (Ln) activated phosphors are a major topic in both basic and applied science. The trivalent europium ion (Eu3+) is well recognized for its intense luminescence in the orange/red spectral region, making it useful for a wide range of applications. Because Eu3+ has an even number of electrons in its 4f shell ([Xe]4f 6 ), the ion has non-degenerated ground (7F0) and excited (5D0) energy states, as well as non-overlapping 2S+1LJ multiplets, resulting in emission spectra that are predictable in relation to the host material site symmetry. The solid-state reaction synthesis method was used to make a set of five Eu-doped YxLu1- xNbO4 samples (x=0–1) with a fixed Eu concentration (5%). All the structures crystallize as beta-Fergusonite, in which the Eu ion replaces the Y or Lu ion in a large, low-symmetry octahedron. The excitation and emission spectra of the Eu3+ ion in all composition hosts show characteristic f-f transitions from which Stark energy levels were calculated. Specific features and energy positions of the distinctive 5D0→7F1 magnetic dipole transition were determined when measured with higher resolution and spectra deconvolution was utilized. The maximum ΔE splitting of the 7F1 manifold's Stark splitting and the asymmetry ratio R all show Y/Lu content-dependent trends. Calculations based on Judd-Ofelt theory were utilized to determine specific quantities. The lowest non-radiative deexcitation rate was observed with x = 1, resulting in the conclusion that LuNbO4 is a better host-matrix for Eu3+ emission than other compositions.
PB  - Society for science development of Serbia, Belgrade
C3  - The 6th International Conference on the Physics of Optical Materials and Devices & The 5th International Workshop of Persistent and Photostimulable Phosphors
T1  - Photoluminescent Properties of the Eu3+ ion in YNbO4-LuNbO4 Solid Solution
UR  - https://hdl.handle.net/21.15107/rcub_vinar_11341
ER  - 

@conference{
author = "Sekulić, Milica and Đačanin Far, Ljubica and Dramićanin, Tatjana and Ćirić, Aleksandar and Dramićanin, Miroslav and Đorđević, Vesna",
year = "2022",
abstract = "Lanthanide (Ln) activated phosphors are a major topic in both basic and applied science. The trivalent europium ion (Eu3+) is well recognized for its intense luminescence in the orange/red spectral region, making it useful for a wide range of applications. Because Eu3+ has an even number of electrons in its 4f shell ([Xe]4f 6 ), the ion has non-degenerated ground (7F0) and excited (5D0) energy states, as well as non-overlapping 2S+1LJ multiplets, resulting in emission spectra that are predictable in relation to the host material site symmetry. The solid-state reaction synthesis method was used to make a set of five Eu-doped YxLu1- xNbO4 samples (x=0–1) with a fixed Eu concentration (5%). All the structures crystallize as beta-Fergusonite, in which the Eu ion replaces the Y or Lu ion in a large, low-symmetry octahedron. The excitation and emission spectra of the Eu3+ ion in all composition hosts show characteristic f-f transitions from which Stark energy levels were calculated. Specific features and energy positions of the distinctive 5D0→7F1 magnetic dipole transition were determined when measured with higher resolution and spectra deconvolution was utilized. The maximum ΔE splitting of the 7F1 manifold's Stark splitting and the asymmetry ratio R all show Y/Lu content-dependent trends. Calculations based on Judd-Ofelt theory were utilized to determine specific quantities. The lowest non-radiative deexcitation rate was observed with x = 1, resulting in the conclusion that LuNbO4 is a better host-matrix for Eu3+ emission than other compositions.",
publisher = "Society for science development of Serbia, Belgrade",
journal = "The 6th International Conference on the Physics of Optical Materials and Devices & The 5th International Workshop of Persistent and Photostimulable Phosphors",
title = "Photoluminescent Properties of the Eu3+ ion in YNbO4-LuNbO4 Solid Solution",
url = "https://hdl.handle.net/21.15107/rcub_vinar_11341"
}

Sekulić, M., Đačanin Far, L., Dramićanin, T., Ćirić, A., Dramićanin, M.,& Đorđević, V.. (2022). Photoluminescent Properties of the Eu3+ ion in YNbO4-LuNbO4 Solid Solution. in The 6th International Conference on the Physics of Optical Materials and Devices & The 5th International Workshop of Persistent and Photostimulable Phosphors
Society for science development of Serbia, Belgrade..
https://hdl.handle.net/21.15107/rcub_vinar_11341

Sekulić M, Đačanin Far L, Dramićanin T, Ćirić A, Dramićanin M, Đorđević V. Photoluminescent Properties of the Eu3+ ion in YNbO4-LuNbO4 Solid Solution. in The 6th International Conference on the Physics of Optical Materials and Devices & The 5th International Workshop of Persistent and Photostimulable Phosphors. 2022;.
https://hdl.handle.net/21.15107/rcub_vinar_11341 .

Sekulić, Milica, Đačanin Far, Ljubica, Dramićanin, Tatjana, Ćirić, Aleksandar, Dramićanin, Miroslav, Đorđević, Vesna, "Photoluminescent Properties of the Eu3+ ion in YNbO4-LuNbO4 Solid Solution" in The 6th International Conference on the Physics of Optical Materials and Devices & The 5th International Workshop of Persistent and Photostimulable Phosphors (2022),
https://hdl.handle.net/21.15107/rcub_vinar_11341 .

TY  - JOUR
AU  - Periša, Jovana
AU  - Ristić, Zoran
AU  - Đorđević, Vesna R.
AU  - Sekulić, Milica
AU  - Dramićanin, Tatjana
AU  - Antić, Željka
AU  - Dramićanin, Miroslav
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9859
AB  - The multiparametric luminescence thermometry with Dy3+, Cr3+ double activated yttrium aluminium garnet – YAG is demonstrated. Phospors were synthesized via Pechini method and their structure is confirmed by X-ray diffraction analysis. Mean crystallite size of powders was calculated to be ~22 nm. Morphology was investigated using scanning electron microscopy showing combination of dense, different size chunks constituted of spherical particles bellow 50 nm in size. Photoluminescence emission spectra of the Dy3+, Cr3+ double activated YAG consist of blue and yellow Dy3+ emissions and the broad, deep red Cr3+ emission. The decrease in the Dy3+ emission intensity with the increase in the Cr3+ content indicates the efficient energy transfer from Dy3+ to Cr3+ of ~90%. Temperature-dependant photoluminescence emission measurements are performed under 484 nm and 582 nm excitation in the steady-state domain and in the 175 K–650 K temperature range. The noted alterations of luminescence with temperature present an excellent base for studying the multiparametric temperature readouts. The luminescence intensity ratio, the most frequently exploited luminescent thermometry temperature readout method, was tested using: i) the combination of Dy3+ and Cr3+ emissions, ii) using the double excitation approach, and iii) using Cr3+ emission only, with relative sensitivities of 0.64 %K−1 at 175 K, 0.96 %K−1 at 200 K and 2.2 %K−1 at 200 K, respectively.
T2  - Journal of Luminescence
T1  - Multiparametric luminescence thermometry from Dy3+, Cr3+ double activated YAG
VL  - 238
SP  - 118306
DO  - 10.1016/j.jlumin.2021.118306
ER  - 

@article{
author = "Periša, Jovana and Ristić, Zoran and Đorđević, Vesna R. and Sekulić, Milica and Dramićanin, Tatjana and Antić, Željka and Dramićanin, Miroslav",
year = "2021",
abstract = "The multiparametric luminescence thermometry with Dy3+, Cr3+ double activated yttrium aluminium garnet – YAG is demonstrated. Phospors were synthesized via Pechini method and their structure is confirmed by X-ray diffraction analysis. Mean crystallite size of powders was calculated to be ~22 nm. Morphology was investigated using scanning electron microscopy showing combination of dense, different size chunks constituted of spherical particles bellow 50 nm in size. Photoluminescence emission spectra of the Dy3+, Cr3+ double activated YAG consist of blue and yellow Dy3+ emissions and the broad, deep red Cr3+ emission. The decrease in the Dy3+ emission intensity with the increase in the Cr3+ content indicates the efficient energy transfer from Dy3+ to Cr3+ of ~90%. Temperature-dependant photoluminescence emission measurements are performed under 484 nm and 582 nm excitation in the steady-state domain and in the 175 K–650 K temperature range. The noted alterations of luminescence with temperature present an excellent base for studying the multiparametric temperature readouts. The luminescence intensity ratio, the most frequently exploited luminescent thermometry temperature readout method, was tested using: i) the combination of Dy3+ and Cr3+ emissions, ii) using the double excitation approach, and iii) using Cr3+ emission only, with relative sensitivities of 0.64 %K−1 at 175 K, 0.96 %K−1 at 200 K and 2.2 %K−1 at 200 K, respectively.",
journal = "Journal of Luminescence",
title = "Multiparametric luminescence thermometry from Dy3+, Cr3+ double activated YAG",
volume = "238",
pages = "118306",
doi = "10.1016/j.jlumin.2021.118306"
}

Periša, J., Ristić, Z., Đorđević, V. R., Sekulić, M., Dramićanin, T., Antić, Ž.,& Dramićanin, M.. (2021). Multiparametric luminescence thermometry from Dy3+, Cr3+ double activated YAG. in Journal of Luminescence, 238, 118306.
https://doi.org/10.1016/j.jlumin.2021.118306

Periša J, Ristić Z, Đorđević VR, Sekulić M, Dramićanin T, Antić Ž, Dramićanin M. Multiparametric luminescence thermometry from Dy3+, Cr3+ double activated YAG. in Journal of Luminescence. 2021;238:118306.
doi:10.1016/j.jlumin.2021.118306 .

Periša, Jovana, Ristić, Zoran, Đorđević, Vesna R., Sekulić, Milica, Dramićanin, Tatjana, Antić, Željka, Dramićanin, Miroslav, "Multiparametric luminescence thermometry from Dy3+, Cr3+ double activated YAG" in Journal of Luminescence, 238 (2021):118306,
https://doi.org/10.1016/j.jlumin.2021.118306 . .

TY  - JOUR
AU  - Dramićanin, Tatjana
AU  - Zeković, Ivana Lj.
AU  - Periša, Jovana
AU  - Dramićanin, Miroslav
PY  - 2019
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8434
AB  - Fluorescence excitation-emission matrices were measured for 111 samples of different types of beer and studied by the parallel factor analysis (PARAFAC). The 5-component PARAFAC model was found to suitably describes the beer fluorescence, accounting for 99.4% of the fluorescence variance in the measured set of samples, and providing the completely resolved excitation and emission spectra of each component. The model was chosen based on a model’s core consistency and split-half analysis. It is shown that beer fluorescence is the sum of fluorescence of aromatic amino acids (tryptophan, tyrosine, and phenylalanine), different forms of vitamin B, and phenolic compounds. Obtained PARAFAC model of beer fluorescence demonstrated the potential for the quantification and quality analysis of beer fluorophores and classification of different beer types. © 2019, Springer Science+Business Media, LLC, part of Springer Nature.
T2  - Journal of Fluorescence
T1  - The Parallel Factor Analysis of Beer Fluorescence
VL  - 29
IS  - 5
SP  - 1103
EP  - 1111
DO  - 10.1007/s10895-019-02421-0
ER  - 

@article{
author = "Dramićanin, Tatjana and Zeković, Ivana Lj. and Periša, Jovana and Dramićanin, Miroslav",
year = "2019",
abstract = "Fluorescence excitation-emission matrices were measured for 111 samples of different types of beer and studied by the parallel factor analysis (PARAFAC). The 5-component PARAFAC model was found to suitably describes the beer fluorescence, accounting for 99.4% of the fluorescence variance in the measured set of samples, and providing the completely resolved excitation and emission spectra of each component. The model was chosen based on a model’s core consistency and split-half analysis. It is shown that beer fluorescence is the sum of fluorescence of aromatic amino acids (tryptophan, tyrosine, and phenylalanine), different forms of vitamin B, and phenolic compounds. Obtained PARAFAC model of beer fluorescence demonstrated the potential for the quantification and quality analysis of beer fluorophores and classification of different beer types. © 2019, Springer Science+Business Media, LLC, part of Springer Nature.",
journal = "Journal of Fluorescence",
title = "The Parallel Factor Analysis of Beer Fluorescence",
volume = "29",
number = "5",
pages = "1103-1111",
doi = "10.1007/s10895-019-02421-0"
}

Dramićanin, T., Zeković, I. Lj., Periša, J.,& Dramićanin, M.. (2019). The Parallel Factor Analysis of Beer Fluorescence. in Journal of Fluorescence, 29(5), 1103-1111.
https://doi.org/10.1007/s10895-019-02421-0

Dramićanin T, Zeković IL, Periša J, Dramićanin M. The Parallel Factor Analysis of Beer Fluorescence. in Journal of Fluorescence. 2019;29(5):1103-1111.
doi:10.1007/s10895-019-02421-0 .

Dramićanin, Tatjana, Zeković, Ivana Lj., Periša, Jovana, Dramićanin, Miroslav, "The Parallel Factor Analysis of Beer Fluorescence" in Journal of Fluorescence, 29, no. 5 (2019):1103-1111,
https://doi.org/10.1007/s10895-019-02421-0 . .

TY  - JOUR
AU  - Nedeljković, Milica
AU  - Tanić, Nikola
AU  - Dramićanin, Tatjana
AU  - Milovanović, Zorka M.
AU  - Šušnjar, Snežana
AU  - Milinković, Vedrana
AU  - Vujović, Ivana
AU  - Tanić, Nasta
PY  - 2018
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/7683
AB  - © 2018 Milica Nedeljković et al., published by De Gruyter Open 2018. Background: Triple negative breast cancer (TNBC) is characterized by aggressive clinical course and is unresponsive to anti-HER2 and endocrine therapy. TNBC is difficult to treat and is often lethal. Given the need to find new targets for therapy we explored clinicopathological significance of copy number gain of FGFR1 and c-MYC. Our aim was to determine the impact of FGFR1 and c-MYC copy number gain on clinical course and outcome of TNBC. Methods: FGFR1 and c-MYC gene copy number alterations were evaluated in 78 archive TNBC samples using TaqMan based quantitative real time PCR assays. Results: 50% of samples had increased c-MYC copy number. c-MYC copy number gain was associated with TNBC in contrast to ER positive cancers. Our results showed significant correlation between c-MYC copy number gain and high grade of TNBCs. This suggests that c-MYC copy number could be an useful prognostic marker for TNBC patients. c-MYC copy number gain was associated with high pTNM stage as well as lobular and medullary tumor subtypes. 43% of samples had increased FGFR1 copy number. No correlations between FGFR1 copy number gain and clinicopathological variables were observed. Conclusions: We identified c-MYC copy number gain as a prognostic marker for TNBC. Our results indicate that c- MYC may contribute to TNBC progression. We observed no significant association between c-MYC and/or FGFR1 copy number status and patient survival.
T2  - Journal of Medical Biochemistry
T1  - Importance of Copy Number Alterations of FGFR1 and C-MYC Genes in Triple Negative Breast Cancer
T1  - Značaj promena broja kopija FGFR1 i c-MYC gena u trostruko negativnim karcinomima dojke
VL  - 37
IS  - 2
SP  - 1
EP  - 8
DO  - 10.1515/jomb-2018-0012
ER  - 

@article{
author = "Nedeljković, Milica and Tanić, Nikola and Dramićanin, Tatjana and Milovanović, Zorka M. and Šušnjar, Snežana and Milinković, Vedrana and Vujović, Ivana and Tanić, Nasta",
year = "2018",
abstract = "© 2018 Milica Nedeljković et al., published by De Gruyter Open 2018. Background: Triple negative breast cancer (TNBC) is characterized by aggressive clinical course and is unresponsive to anti-HER2 and endocrine therapy. TNBC is difficult to treat and is often lethal. Given the need to find new targets for therapy we explored clinicopathological significance of copy number gain of FGFR1 and c-MYC. Our aim was to determine the impact of FGFR1 and c-MYC copy number gain on clinical course and outcome of TNBC. Methods: FGFR1 and c-MYC gene copy number alterations were evaluated in 78 archive TNBC samples using TaqMan based quantitative real time PCR assays. Results: 50% of samples had increased c-MYC copy number. c-MYC copy number gain was associated with TNBC in contrast to ER positive cancers. Our results showed significant correlation between c-MYC copy number gain and high grade of TNBCs. This suggests that c-MYC copy number could be an useful prognostic marker for TNBC patients. c-MYC copy number gain was associated with high pTNM stage as well as lobular and medullary tumor subtypes. 43% of samples had increased FGFR1 copy number. No correlations between FGFR1 copy number gain and clinicopathological variables were observed. Conclusions: We identified c-MYC copy number gain as a prognostic marker for TNBC. Our results indicate that c- MYC may contribute to TNBC progression. We observed no significant association between c-MYC and/or FGFR1 copy number status and patient survival.",
journal = "Journal of Medical Biochemistry",
title = "Importance of Copy Number Alterations of FGFR1 and C-MYC Genes in Triple Negative Breast Cancer, Značaj promena broja kopija FGFR1 i c-MYC gena u trostruko negativnim karcinomima dojke",
volume = "37",
number = "2",
pages = "1-8",
doi = "10.1515/jomb-2018-0012"
}

Nedeljković, M., Tanić, N., Dramićanin, T., Milovanović, Z. M., Šušnjar, S., Milinković, V., Vujović, I.,& Tanić, N.. (2018). Importance of Copy Number Alterations of FGFR1 and C-MYC Genes in Triple Negative Breast Cancer. in Journal of Medical Biochemistry, 37(2), 1-8.
https://doi.org/10.1515/jomb-2018-0012

Nedeljković M, Tanić N, Dramićanin T, Milovanović ZM, Šušnjar S, Milinković V, Vujović I, Tanić N. Importance of Copy Number Alterations of FGFR1 and C-MYC Genes in Triple Negative Breast Cancer. in Journal of Medical Biochemistry. 2018;37(2):1-8.
doi:10.1515/jomb-2018-0012 .

Nedeljković, Milica, Tanić, Nikola, Dramićanin, Tatjana, Milovanović, Zorka M., Šušnjar, Snežana, Milinković, Vedrana, Vujović, Ivana, Tanić, Nasta, "Importance of Copy Number Alterations of FGFR1 and C-MYC Genes in Triple Negative Breast Cancer" in Journal of Medical Biochemistry, 37, no. 2 (2018):1-8,
https://doi.org/10.1515/jomb-2018-0012 . .

TY  - JOUR
AU  - Dramićanin, Tatjana
AU  - Lenhardt Acković, Lea
AU  - Zeković, Ivana Lj.
AU  - Dramićanin, Miroslav
PY  - 2018
UR  - https://www.hindawi.com/journals/jspec/2018/8395212/
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/7800
AB  - Honey is a frequent target of adulteration through inappropriate production practices and origin mislabelling. Current methods for the detection of adulterated honey are time and labor consuming, require highly skilled personnel, and lengthy sample preparation. Fluorescence spectroscopy overcomes such drawbacks, as it is fast and noncontact and requires minimal sample preparation. In this paper, the application of fluorescence spectroscopy coupled with statistical tools for the detection of adulterated honey is demonstrated. For this purpose, fluorescence excitation-emission matrices were measured for 99 samples of different types of natural honey and 15 adulterated honey samples (in 3 technical replicas for each sample). Statistical t -test showed that significant differences between fluorescence of natural and adulterated honey samples exist in 5 spectral regions: (1) excitation: 240–265 nm, emission: 370–495 nm; (2) excitation: 280–320 nm, emission: 390–470 nm; (3) excitation: 260–285 nm, emission: 320–370 nm; (4) excitation: 310–360 nm, emission: 370–470 nm; and (5) excitation: 375–435 nm, emission: 440–520 nm, in which majority of fluorescence comes from the aromatic amino acids, phenolic compounds, and fluorescent Maillard reaction products. Principal component analysis confirmed these findings and showed that 90% of variance in fluorescence is accumulated in the first two principal components, which can be used for the discrimination of fake honey samples. The classification of honey from fluorescence data is demonstrated with a linear discriminant analysis (LDA). When subjected to LDA, total fluorescence intensities of selected spectral regions provided classification of honey (natural or adulterated) with 100% accuracy. In addition, it is demonstrated that intensities of honey emissions in each of these spectral regions may serve as criteria for the discrimination between natural and fake honey.
T2  - Journal of Spectroscopy
T1  - Detection of Adulterated Honey by Fluorescence Excitation-Emission Matrices
VL  - 2018
SP  - 1
EP  - 6
DO  - 10.1155/2018/8395212
ER  - 

@article{
author = "Dramićanin, Tatjana and Lenhardt Acković, Lea and Zeković, Ivana Lj. and Dramićanin, Miroslav",
year = "2018",
abstract = "Honey is a frequent target of adulteration through inappropriate production practices and origin mislabelling. Current methods for the detection of adulterated honey are time and labor consuming, require highly skilled personnel, and lengthy sample preparation. Fluorescence spectroscopy overcomes such drawbacks, as it is fast and noncontact and requires minimal sample preparation. In this paper, the application of fluorescence spectroscopy coupled with statistical tools for the detection of adulterated honey is demonstrated. For this purpose, fluorescence excitation-emission matrices were measured for 99 samples of different types of natural honey and 15 adulterated honey samples (in 3 technical replicas for each sample). Statistical t -test showed that significant differences between fluorescence of natural and adulterated honey samples exist in 5 spectral regions: (1) excitation: 240–265 nm, emission: 370–495 nm; (2) excitation: 280–320 nm, emission: 390–470 nm; (3) excitation: 260–285 nm, emission: 320–370 nm; (4) excitation: 310–360 nm, emission: 370–470 nm; and (5) excitation: 375–435 nm, emission: 440–520 nm, in which majority of fluorescence comes from the aromatic amino acids, phenolic compounds, and fluorescent Maillard reaction products. Principal component analysis confirmed these findings and showed that 90% of variance in fluorescence is accumulated in the first two principal components, which can be used for the discrimination of fake honey samples. The classification of honey from fluorescence data is demonstrated with a linear discriminant analysis (LDA). When subjected to LDA, total fluorescence intensities of selected spectral regions provided classification of honey (natural or adulterated) with 100% accuracy. In addition, it is demonstrated that intensities of honey emissions in each of these spectral regions may serve as criteria for the discrimination between natural and fake honey.",
journal = "Journal of Spectroscopy",
title = "Detection of Adulterated Honey by Fluorescence Excitation-Emission Matrices",
volume = "2018",
pages = "1-6",
doi = "10.1155/2018/8395212"
}

Dramićanin, T., Lenhardt Acković, L., Zeković, I. Lj.,& Dramićanin, M.. (2018). Detection of Adulterated Honey by Fluorescence Excitation-Emission Matrices. in Journal of Spectroscopy, 2018, 1-6.
https://doi.org/10.1155/2018/8395212

Dramićanin T, Lenhardt Acković L, Zeković IL, Dramićanin M. Detection of Adulterated Honey by Fluorescence Excitation-Emission Matrices. in Journal of Spectroscopy. 2018;2018:1-6.
doi:10.1155/2018/8395212 .

Dramićanin, Tatjana, Lenhardt Acković, Lea, Zeković, Ivana Lj., Dramićanin, Miroslav, "Detection of Adulterated Honey by Fluorescence Excitation-Emission Matrices" in Journal of Spectroscopy, 2018 (2018):1-6,
https://doi.org/10.1155/2018/8395212 . .

TY  - JOUR
AU  - Lenhardt, Lea I.
AU  - Zeković, Ivana Lj.
AU  - Dramićanin, Tatjana
AU  - Milićević, Bojana R.
AU  - Burojević, Jovana
AU  - Dramićanin, Miroslav
PY  - 2017
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/1535
AB  - This paper presents parallel factor analysis (PARAFAC) of fluorescence of cereal flours. Excitation emission matrices (EEMs) of different cereal flours (wheat, corn, rye, rice, oat, spelt, barley and buckwheat) were measured in a front-face configuration over the ultraviolet-visible spectral range. EEMs showed that flours strongly fluoresce in two spectral regions, where amino acids, tocopherols, pyridoxine and 4-aminobenzoic acid show intense emissions. 4-component PARAFAC was used to model flour fluorescence and to decompose EEMs into excitation and emission spectra of each component. PARAFAC also provided relative concentrations of these components. The largest differences between flours were found in the concentration levels of the first and third component. Finally, variations in concentrations of PARAFAC modelled components were analysed in relation to the botanical origin of flour samples. (C) 2017 Elsevier Ltd. All rights reserved.
T2  - Food Chemistry
T1  - Characterization of cereal flours by fluorescence spectroscopy coupled with PARAFAC
VL  - 229
SP  - 165
EP  - 171
DO  - 10.1016/j.foodchem.2017.02.070
ER  - 

@article{
author = "Lenhardt, Lea I. and Zeković, Ivana Lj. and Dramićanin, Tatjana and Milićević, Bojana R. and Burojević, Jovana and Dramićanin, Miroslav",
year = "2017",
abstract = "This paper presents parallel factor analysis (PARAFAC) of fluorescence of cereal flours. Excitation emission matrices (EEMs) of different cereal flours (wheat, corn, rye, rice, oat, spelt, barley and buckwheat) were measured in a front-face configuration over the ultraviolet-visible spectral range. EEMs showed that flours strongly fluoresce in two spectral regions, where amino acids, tocopherols, pyridoxine and 4-aminobenzoic acid show intense emissions. 4-component PARAFAC was used to model flour fluorescence and to decompose EEMs into excitation and emission spectra of each component. PARAFAC also provided relative concentrations of these components. The largest differences between flours were found in the concentration levels of the first and third component. Finally, variations in concentrations of PARAFAC modelled components were analysed in relation to the botanical origin of flour samples. (C) 2017 Elsevier Ltd. All rights reserved.",
journal = "Food Chemistry",
title = "Characterization of cereal flours by fluorescence spectroscopy coupled with PARAFAC",
volume = "229",
pages = "165-171",
doi = "10.1016/j.foodchem.2017.02.070"
}

Lenhardt, L. I., Zeković, I. Lj., Dramićanin, T., Milićević, B. R., Burojević, J.,& Dramićanin, M.. (2017). Characterization of cereal flours by fluorescence spectroscopy coupled with PARAFAC. in Food Chemistry, 229, 165-171.
https://doi.org/10.1016/j.foodchem.2017.02.070

Lenhardt LI, Zeković IL, Dramićanin T, Milićević BR, Burojević J, Dramićanin M. Characterization of cereal flours by fluorescence spectroscopy coupled with PARAFAC. in Food Chemistry. 2017;229:165-171.
doi:10.1016/j.foodchem.2017.02.070 .

Lenhardt, Lea I., Zeković, Ivana Lj., Dramićanin, Tatjana, Milićević, Bojana R., Burojević, Jovana, Dramićanin, Miroslav, "Characterization of cereal flours by fluorescence spectroscopy coupled with PARAFAC" in Food Chemistry, 229 (2017):165-171,
https://doi.org/10.1016/j.foodchem.2017.02.070 . .

TY  - JOUR
AU  - Lenhardt, Lea I.
AU  - Bro, Rasmus
AU  - Zeković, Ivana Lj.
AU  - Dramićanin, Tatjana
AU  - Dramićanin, Miroslav
PY  - 2015
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/382
AB  - Fluorescence spectroscopy coupled with parallel factor analysis (PARAFAC) and Partial least squares Discriminant Analysis (PLS DA) were used for characterization and classification of honey. Excitation emission spectra were obtained for 95 honey samples of different botanical origin (acacia, sunflower, linden, meadow, and fake honey) by recording emission from 270 to 640 nm with excitation in the range of 240-500 nm. The number of fluorophores present in honey, excitation and emission spectra of each fluorophore, and their relative concentration are determined using a six-component PARAFAC model. Emissions from phenolic compounds and Maillard reaction products exhibited the largest difference among classes of honey of different botanical origin. The PLS DA classification model, constructed from PARAFAC model scores, detected fake honey samples with 100% sensitivity and specificity. Honey samples were also classified using PLS DA with errors of 0.5% for linden, 10% for acacia, and about 20% for both sunflower and meadow mix. (c) 2014 Elsevier Ltd. All rights reserved.
T2  - Food Chemistry
T1  - Fluorescence spectroscopy coupled with PARAFAC and PLS DA for characterization and classification of honey
VL  - 175
SP  - 284
EP  - 291
DO  - 10.1016/j.foodchem.2014.11.162
ER  - 

@article{
author = "Lenhardt, Lea I. and Bro, Rasmus and Zeković, Ivana Lj. and Dramićanin, Tatjana and Dramićanin, Miroslav",
year = "2015",
abstract = "Fluorescence spectroscopy coupled with parallel factor analysis (PARAFAC) and Partial least squares Discriminant Analysis (PLS DA) were used for characterization and classification of honey. Excitation emission spectra were obtained for 95 honey samples of different botanical origin (acacia, sunflower, linden, meadow, and fake honey) by recording emission from 270 to 640 nm with excitation in the range of 240-500 nm. The number of fluorophores present in honey, excitation and emission spectra of each fluorophore, and their relative concentration are determined using a six-component PARAFAC model. Emissions from phenolic compounds and Maillard reaction products exhibited the largest difference among classes of honey of different botanical origin. The PLS DA classification model, constructed from PARAFAC model scores, detected fake honey samples with 100% sensitivity and specificity. Honey samples were also classified using PLS DA with errors of 0.5% for linden, 10% for acacia, and about 20% for both sunflower and meadow mix. (c) 2014 Elsevier Ltd. All rights reserved.",
journal = "Food Chemistry",
title = "Fluorescence spectroscopy coupled with PARAFAC and PLS DA for characterization and classification of honey",
volume = "175",
pages = "284-291",
doi = "10.1016/j.foodchem.2014.11.162"
}

Lenhardt, L. I., Bro, R., Zeković, I. Lj., Dramićanin, T.,& Dramićanin, M.. (2015). Fluorescence spectroscopy coupled with PARAFAC and PLS DA for characterization and classification of honey. in Food Chemistry, 175, 284-291.
https://doi.org/10.1016/j.foodchem.2014.11.162

Lenhardt LI, Bro R, Zeković IL, Dramićanin T, Dramićanin M. Fluorescence spectroscopy coupled with PARAFAC and PLS DA for characterization and classification of honey. in Food Chemistry. 2015;175:284-291.
doi:10.1016/j.foodchem.2014.11.162 .

Lenhardt, Lea I., Bro, Rasmus, Zeković, Ivana Lj., Dramićanin, Tatjana, Dramićanin, Miroslav, "Fluorescence spectroscopy coupled with PARAFAC and PLS DA for characterization and classification of honey" in Food Chemistry, 175 (2015):284-291,
https://doi.org/10.1016/j.foodchem.2014.11.162 . .

TY  - JOUR
AU  - Stanković, Tijana
AU  - Milinković, Vedrana
AU  - Banković, Jasna Z.
AU  - Dinić, Jelena
AU  - Tanić, Nasta
AU  - Dramićanin, Tatjana
AU  - Tanić, Nikola
PY  - 2014
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/143
AB  - p53, p16 and PTEN are the most commonly altered tumor suppressor genes in human cancers. In the present study, we compared the presence of individual and multiple alterations of these tumor suppressors in non-small cell lung carcinoma (NSCLC), glioma and breast carcinoma, in order to evaluate specificity of each tumor type regarding the number of altered genes, as well as their combinations. We tested the mutational status, loss of heterozygosity and methylation status of these genes. Effects of gene alterations on patients survival were also assessed. In NSCLC samples, single gene alterations occurred rarely, while there was considerable increase in incidence of double gene alterations. Furthermore, coexistence of aberrant p53, PTEN and p16 was the most frequent and had significant adverse effect on the survival of NSCLC patients. On the contrary, in glioma and breast cancer specimens, substantial number of cases had aberrant single gene only. Moreover, glioma and breast carcinoma also differ in genotypes that were predominant. Specifically, in glioma samples, prevalent were co-alterations of PTEN and p16, followed by aberrant only PTEN. In breast cancer samples, alterations in all three genes as well as in p53 and p16 were the most common. Moreover, PTEN was altered exclusively with aberrant p53, with statistically significant correlation among them. Overall, our results suggest that NSCLC, glioma and breast cancer need different approaches in molecular diagnosis and treatment with particular attention toward the number and combination of targeted genes. (C) 2014 Elsevier Masson SAS. All rights reserved.
T2  - Biomedicine and Pharmacotherapy
T1  - Comparative analyses of individual and multiple alterations of p53, PTEN and p16 in non-small cell lung carcinoma, glioma and breast carcinoma samples
VL  - 68
IS  - 5
SP  - 521
EP  - 526
DO  - 10.1016/j.biopha.2014.03.014
ER  - 

@article{
author = "Stanković, Tijana and Milinković, Vedrana and Banković, Jasna Z. and Dinić, Jelena and Tanić, Nasta and Dramićanin, Tatjana and Tanić, Nikola",
year = "2014",
abstract = "p53, p16 and PTEN are the most commonly altered tumor suppressor genes in human cancers. In the present study, we compared the presence of individual and multiple alterations of these tumor suppressors in non-small cell lung carcinoma (NSCLC), glioma and breast carcinoma, in order to evaluate specificity of each tumor type regarding the number of altered genes, as well as their combinations. We tested the mutational status, loss of heterozygosity and methylation status of these genes. Effects of gene alterations on patients survival were also assessed. In NSCLC samples, single gene alterations occurred rarely, while there was considerable increase in incidence of double gene alterations. Furthermore, coexistence of aberrant p53, PTEN and p16 was the most frequent and had significant adverse effect on the survival of NSCLC patients. On the contrary, in glioma and breast cancer specimens, substantial number of cases had aberrant single gene only. Moreover, glioma and breast carcinoma also differ in genotypes that were predominant. Specifically, in glioma samples, prevalent were co-alterations of PTEN and p16, followed by aberrant only PTEN. In breast cancer samples, alterations in all three genes as well as in p53 and p16 were the most common. Moreover, PTEN was altered exclusively with aberrant p53, with statistically significant correlation among them. Overall, our results suggest that NSCLC, glioma and breast cancer need different approaches in molecular diagnosis and treatment with particular attention toward the number and combination of targeted genes. (C) 2014 Elsevier Masson SAS. All rights reserved.",
journal = "Biomedicine and Pharmacotherapy",
title = "Comparative analyses of individual and multiple alterations of p53, PTEN and p16 in non-small cell lung carcinoma, glioma and breast carcinoma samples",
volume = "68",
number = "5",
pages = "521-526",
doi = "10.1016/j.biopha.2014.03.014"
}

Stanković, T., Milinković, V., Banković, J. Z., Dinić, J., Tanić, N., Dramićanin, T.,& Tanić, N.. (2014). Comparative analyses of individual and multiple alterations of p53, PTEN and p16 in non-small cell lung carcinoma, glioma and breast carcinoma samples. in Biomedicine and Pharmacotherapy, 68(5), 521-526.
https://doi.org/10.1016/j.biopha.2014.03.014

Stanković T, Milinković V, Banković JZ, Dinić J, Tanić N, Dramićanin T, Tanić N. Comparative analyses of individual and multiple alterations of p53, PTEN and p16 in non-small cell lung carcinoma, glioma and breast carcinoma samples. in Biomedicine and Pharmacotherapy. 2014;68(5):521-526.
doi:10.1016/j.biopha.2014.03.014 .

Stanković, Tijana, Milinković, Vedrana, Banković, Jasna Z., Dinić, Jelena, Tanić, Nasta, Dramićanin, Tatjana, Tanić, Nikola, "Comparative analyses of individual and multiple alterations of p53, PTEN and p16 in non-small cell lung carcinoma, glioma and breast carcinoma samples" in Biomedicine and Pharmacotherapy, 68, no. 5 (2014):521-526,
https://doi.org/10.1016/j.biopha.2014.03.014 . .

TY  - JOUR
AU  - Lenhardt, Lea I.
AU  - Zeković, Ivana Lj.
AU  - Dramićanin, Tatjana
AU  - Dramićanin, Miroslav
AU  - Bro, Rasmus
PY  - 2014
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/5981
AB  - Front-face synchronous fluorescence spectroscopy combined with chemometrics is used to classify honey samples according to their botanical origin. Synchronous fluorescence spectra of three monofloral (linden, sunflower, and acacia), polyfloral (meadow mix), and fake (fake acacia and linden) honey types (109 samples) were collected in an excitation range of 240-500 nm for synchronous wavelength intervals of 30-300 nm. Chemometric analysis of the gathered data included principal component analysis and partial least squares discriminant analysis. Mean cross-validated classification errors of 0.2 and 4.8% were found for a model that accounts only for monofloral samples and for a model that includes both the monofloral and polyfloral groups, respectively. The results demonstrate that single synchronous fluorescence spectra of different honeys differ significantly because of their distinct physical and chemical characteristics and provide sufficient data for the clear differentiation among honey groups. The spectra of fake honey samples showed pronounced differences from those of genuine honey, and these samples are easily recognized on the basis of their synchronous fluorescence spectra. The study demonstrated that this method is a valuable and promising technique for honey authentication.
T2  - Applied Spectroscopy
T1  - Determination of the Botanical Origin of Honey by Front-Face Synchronous Fluorescence Spectroscopy
VL  - 68
IS  - 5
SP  - 557
EP  - 563
DO  - 10.1366/13-07325
ER  - 

@article{
author = "Lenhardt, Lea I. and Zeković, Ivana Lj. and Dramićanin, Tatjana and Dramićanin, Miroslav and Bro, Rasmus",
year = "2014",
abstract = "Front-face synchronous fluorescence spectroscopy combined with chemometrics is used to classify honey samples according to their botanical origin. Synchronous fluorescence spectra of three monofloral (linden, sunflower, and acacia), polyfloral (meadow mix), and fake (fake acacia and linden) honey types (109 samples) were collected in an excitation range of 240-500 nm for synchronous wavelength intervals of 30-300 nm. Chemometric analysis of the gathered data included principal component analysis and partial least squares discriminant analysis. Mean cross-validated classification errors of 0.2 and 4.8% were found for a model that accounts only for monofloral samples and for a model that includes both the monofloral and polyfloral groups, respectively. The results demonstrate that single synchronous fluorescence spectra of different honeys differ significantly because of their distinct physical and chemical characteristics and provide sufficient data for the clear differentiation among honey groups. The spectra of fake honey samples showed pronounced differences from those of genuine honey, and these samples are easily recognized on the basis of their synchronous fluorescence spectra. The study demonstrated that this method is a valuable and promising technique for honey authentication.",
journal = "Applied Spectroscopy",
title = "Determination of the Botanical Origin of Honey by Front-Face Synchronous Fluorescence Spectroscopy",
volume = "68",
number = "5",
pages = "557-563",
doi = "10.1366/13-07325"
}

Lenhardt, L. I., Zeković, I. Lj., Dramićanin, T., Dramićanin, M.,& Bro, R.. (2014). Determination of the Botanical Origin of Honey by Front-Face Synchronous Fluorescence Spectroscopy. in Applied Spectroscopy, 68(5), 557-563.
https://doi.org/10.1366/13-07325

Lenhardt LI, Zeković IL, Dramićanin T, Dramićanin M, Bro R. Determination of the Botanical Origin of Honey by Front-Face Synchronous Fluorescence Spectroscopy. in Applied Spectroscopy. 2014;68(5):557-563.
doi:10.1366/13-07325 .

Lenhardt, Lea I., Zeković, Ivana Lj., Dramićanin, Tatjana, Dramićanin, Miroslav, Bro, Rasmus, "Determination of the Botanical Origin of Honey by Front-Face Synchronous Fluorescence Spectroscopy" in Applied Spectroscopy, 68, no. 5 (2014):557-563,
https://doi.org/10.1366/13-07325 . .

TY  - JOUR
AU  - Zeković, Ivana Lj.
AU  - Dramićanin, Tatjana
AU  - Lenhardt, Lea I.
AU  - Bandic, Jadran
AU  - Dramićanin, Miroslav
PY  - 2014
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/6088
AB  - Novel optical spectroscopy and imaging methods may be valuable in the early detection of cancer. This paper reports differences in the luminescence responses of pigmented skin lesions (melanomas and nevi) and apparently normal non-pigmented human skin, based on analyses of synchronous luminescence spectroscopy. measurements. Measurements were performed in the excitation range of 330-545 nm, with synchronous intervals varying from 30 120 nm. Normal skin, nevi, and melanomas differ in the way they fluoresce, and these differences are more distinct in the synchronous fluorescence spectra than in the conventional emission and excitation spectra. The differences in the fluorescence characteristics of pigmented and normal skin samples were ascribed to differences in concentrations of endogenous fluorophores and chromophores. Principal component and linear discriminant analysis of the synchronous spectra measured at different synchronous intervals showed that the greatest variance among the sample groups was at the 70 nm interval spectra. These spectra were then used to create partial least squares discriminant analysis-based classification models. Evaluation of the quality of these models from the receiver operating characteristic curves showed they performed well, with a maximum value of 1 for the area under the curve for melanoma detection. Hence, synchronous luminescence spectroscopy coupled with statistical methods may be advantageous in the early detection of skin cancer.
T2  - Applied Spectroscopy
T1  - Discrimination Among Melanoma, Nevi, and Normal Skin by Using Synchronous Luminescence Spectroscopy
VL  - 68
IS  - 8
SP  - 823
EP  - 830
DO  - 10.1366/13-07153
ER  - 

@article{
author = "Zeković, Ivana Lj. and Dramićanin, Tatjana and Lenhardt, Lea I. and Bandic, Jadran and Dramićanin, Miroslav",
year = "2014",
abstract = "Novel optical spectroscopy and imaging methods may be valuable in the early detection of cancer. This paper reports differences in the luminescence responses of pigmented skin lesions (melanomas and nevi) and apparently normal non-pigmented human skin, based on analyses of synchronous luminescence spectroscopy. measurements. Measurements were performed in the excitation range of 330-545 nm, with synchronous intervals varying from 30 120 nm. Normal skin, nevi, and melanomas differ in the way they fluoresce, and these differences are more distinct in the synchronous fluorescence spectra than in the conventional emission and excitation spectra. The differences in the fluorescence characteristics of pigmented and normal skin samples were ascribed to differences in concentrations of endogenous fluorophores and chromophores. Principal component and linear discriminant analysis of the synchronous spectra measured at different synchronous intervals showed that the greatest variance among the sample groups was at the 70 nm interval spectra. These spectra were then used to create partial least squares discriminant analysis-based classification models. Evaluation of the quality of these models from the receiver operating characteristic curves showed they performed well, with a maximum value of 1 for the area under the curve for melanoma detection. Hence, synchronous luminescence spectroscopy coupled with statistical methods may be advantageous in the early detection of skin cancer.",
journal = "Applied Spectroscopy",
title = "Discrimination Among Melanoma, Nevi, and Normal Skin by Using Synchronous Luminescence Spectroscopy",
volume = "68",
number = "8",
pages = "823-830",
doi = "10.1366/13-07153"
}

Zeković, I. Lj., Dramićanin, T., Lenhardt, L. I., Bandic, J.,& Dramićanin, M.. (2014). Discrimination Among Melanoma, Nevi, and Normal Skin by Using Synchronous Luminescence Spectroscopy. in Applied Spectroscopy, 68(8), 823-830.
https://doi.org/10.1366/13-07153

Zeković IL, Dramićanin T, Lenhardt LI, Bandic J, Dramićanin M. Discrimination Among Melanoma, Nevi, and Normal Skin by Using Synchronous Luminescence Spectroscopy. in Applied Spectroscopy. 2014;68(8):823-830.
doi:10.1366/13-07153 .

Zeković, Ivana Lj., Dramićanin, Tatjana, Lenhardt, Lea I., Bandic, Jadran, Dramićanin, Miroslav, "Discrimination Among Melanoma, Nevi, and Normal Skin by Using Synchronous Luminescence Spectroscopy" in Applied Spectroscopy, 68, no. 8 (2014):823-830,
https://doi.org/10.1366/13-07153 . .

TY  - JOUR
AU  - Lenhardt, Lea I.
AU  - Zeković, Ivana Lj.
AU  - Dramićanin, Tatjana
AU  - Tešić, Živoslav
AU  - Milojković-Opsenica, Dušanka M.
AU  - Dramićanin, Miroslav
PY  - 2014
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/7065
AB  - In recent years, the potential of Fourier-transform infrared spectroscopy coupled with different chemometric tools in food analysis has been established. This technique is rapid, low cost, and reliable and requires little sample preparation. In this work, 130 Serbian unifloral honey samples (linden, acacia, and sunflower types) were analyzed using attenuated total reflectance infrared spectroscopy (ATR-IR). For each spectrum, 64 scans were recorded in wavenumbers between 4000 and 500 cm(-1) and at a spectral resolution of 4 cm(-1). These spectra were analyzed using principal component analysis (PCA), and calculated principal components were then used for support vector machine (SVM) training. In this way, the pattern-recognition tool is obtained for building a classification model for determining the botanical origin of honey. The PCA was used to analyze results and to see if the separation between groups of different types of honeys exists. Using the SVM, the classification model was built and classification errors were acquired. It has been observed that this technique is adequate for determining the botanical origin of honey with a success rate of 98.6%. Based on these results, it can be concluded that this technique offers many possibilities for future rapid qualitative analysis of honey.
T2  - Physica Scripta
T1  - Authentication of the botanical origin of unifloral honey by infrared spectroscopy coupled with support vector machine algorithm
VL  - T162
DO  - 10.1088/0031-8949/2014/T162/014042
ER  - 

@article{
author = "Lenhardt, Lea I. and Zeković, Ivana Lj. and Dramićanin, Tatjana and Tešić, Živoslav and Milojković-Opsenica, Dušanka M. and Dramićanin, Miroslav",
year = "2014",
abstract = "In recent years, the potential of Fourier-transform infrared spectroscopy coupled with different chemometric tools in food analysis has been established. This technique is rapid, low cost, and reliable and requires little sample preparation. In this work, 130 Serbian unifloral honey samples (linden, acacia, and sunflower types) were analyzed using attenuated total reflectance infrared spectroscopy (ATR-IR). For each spectrum, 64 scans were recorded in wavenumbers between 4000 and 500 cm(-1) and at a spectral resolution of 4 cm(-1). These spectra were analyzed using principal component analysis (PCA), and calculated principal components were then used for support vector machine (SVM) training. In this way, the pattern-recognition tool is obtained for building a classification model for determining the botanical origin of honey. The PCA was used to analyze results and to see if the separation between groups of different types of honeys exists. Using the SVM, the classification model was built and classification errors were acquired. It has been observed that this technique is adequate for determining the botanical origin of honey with a success rate of 98.6%. Based on these results, it can be concluded that this technique offers many possibilities for future rapid qualitative analysis of honey.",
journal = "Physica Scripta",
title = "Authentication of the botanical origin of unifloral honey by infrared spectroscopy coupled with support vector machine algorithm",
volume = "T162",
doi = "10.1088/0031-8949/2014/T162/014042"
}

Lenhardt, L. I., Zeković, I. Lj., Dramićanin, T., Tešić, Ž., Milojković-Opsenica, D. M.,& Dramićanin, M.. (2014). Authentication of the botanical origin of unifloral honey by infrared spectroscopy coupled with support vector machine algorithm. in Physica Scripta, T162.
https://doi.org/10.1088/0031-8949/2014/T162/014042

Lenhardt LI, Zeković IL, Dramićanin T, Tešić Ž, Milojković-Opsenica DM, Dramićanin M. Authentication of the botanical origin of unifloral honey by infrared spectroscopy coupled with support vector machine algorithm. in Physica Scripta. 2014;T162.
doi:10.1088/0031-8949/2014/T162/014042 .

Lenhardt, Lea I., Zeković, Ivana Lj., Dramićanin, Tatjana, Tešić, Živoslav, Milojković-Opsenica, Dušanka M., Dramićanin, Miroslav, "Authentication of the botanical origin of unifloral honey by infrared spectroscopy coupled with support vector machine algorithm" in Physica Scripta, T162 (2014),
https://doi.org/10.1088/0031-8949/2014/T162/014042 . .

TY  - JOUR
AU  - Tanić, Nasta
AU  - Milinković, Vedrana
AU  - Dramićanin, Tatjana
AU  - Nedeljković, Milica
AU  - Stanković, Tijana
AU  - Milovanović, Zorka M.
AU  - Šušnjar, Snežana
AU  - Milošević, Verica
AU  - Šošić-Jurjević, Branka
AU  - Džodić, Radan R.
AU  - Tanić, Nikola
PY  - 2013
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/5745
AB  - Background: Breast cancer is the most common form of cancer in women. It arises from multiple genetic changes in oncogenes and tumor suppressor genes. Among so far studied oncogenes relatively few, including epdermal growth factor receptor (EGFR), cyclinD1 (CCND1) and c-myc, have been found to play an important role in progression of this type of human malignancy. The aim of this study was to examine the prognostic potential of CCND1, c-myc and EGFR amplification and their possible cooperation in breast carcinogenesis. Methods: Copy number analyses of CCND1 and c-myc genes were done by TaqMan based quantitative real time PCR. Amplification status of EGFR was determined by differential PCR. Results: Amplification of CCND1, c-myc and EGFR oncogene has been found in 20.4%, 26.5% and 26.5% of breast cancer cases, respectively. Analysis showed that amplification of CCND1 oncogene was significantly associated with the stage II of disease while amplification of EGFR gene was significantly associated with overexpression of HER-2/neu. Tumour stage and expression of HER-2/neu appeared to be significant predictors of patients outcome. Stage I patients lived significantly longer then stage III patients (p=0.04) while patients with HER-2/neu overexpression had worse prognoses and lived significantly shorter (p=0.001). Finally, survival of patients who underwent hormone therapy only was significantly longer (p=0.001) then survival of the rest of patients. Conclusions: Amplification of CCND1 or EGFR oncogene is associated with the progression of breast cancer and bad prognosis. No co-ordination in amplification of CCND1, c-myc and EGFR oncogenes were established in this cohort of breast cancer patients.
T2  - Journal of Medical Biochemistry
T1  - Amplification of Cycline D1, C-Myc and Egfr Oncogenes in Tumour Samples of Breast Cancer Patients
VL  - 32
IS  - 4
DO  - 10.2478/jomb-2014-0005
ER  - 

@article{
author = "Tanić, Nasta and Milinković, Vedrana and Dramićanin, Tatjana and Nedeljković, Milica and Stanković, Tijana and Milovanović, Zorka M. and Šušnjar, Snežana and Milošević, Verica and Šošić-Jurjević, Branka and Džodić, Radan R. and Tanić, Nikola",
year = "2013",
abstract = "Background: Breast cancer is the most common form of cancer in women. It arises from multiple genetic changes in oncogenes and tumor suppressor genes. Among so far studied oncogenes relatively few, including epdermal growth factor receptor (EGFR), cyclinD1 (CCND1) and c-myc, have been found to play an important role in progression of this type of human malignancy. The aim of this study was to examine the prognostic potential of CCND1, c-myc and EGFR amplification and their possible cooperation in breast carcinogenesis. Methods: Copy number analyses of CCND1 and c-myc genes were done by TaqMan based quantitative real time PCR. Amplification status of EGFR was determined by differential PCR. Results: Amplification of CCND1, c-myc and EGFR oncogene has been found in 20.4%, 26.5% and 26.5% of breast cancer cases, respectively. Analysis showed that amplification of CCND1 oncogene was significantly associated with the stage II of disease while amplification of EGFR gene was significantly associated with overexpression of HER-2/neu. Tumour stage and expression of HER-2/neu appeared to be significant predictors of patients outcome. Stage I patients lived significantly longer then stage III patients (p=0.04) while patients with HER-2/neu overexpression had worse prognoses and lived significantly shorter (p=0.001). Finally, survival of patients who underwent hormone therapy only was significantly longer (p=0.001) then survival of the rest of patients. Conclusions: Amplification of CCND1 or EGFR oncogene is associated with the progression of breast cancer and bad prognosis. No co-ordination in amplification of CCND1, c-myc and EGFR oncogenes were established in this cohort of breast cancer patients.",
journal = "Journal of Medical Biochemistry",
title = "Amplification of Cycline D1, C-Myc and Egfr Oncogenes in Tumour Samples of Breast Cancer Patients",
volume = "32",
number = "4",
doi = "10.2478/jomb-2014-0005"
}

Tanić, N., Milinković, V., Dramićanin, T., Nedeljković, M., Stanković, T., Milovanović, Z. M., Šušnjar, S., Milošević, V., Šošić-Jurjević, B., Džodić, R. R.,& Tanić, N.. (2013). Amplification of Cycline D1, C-Myc and Egfr Oncogenes in Tumour Samples of Breast Cancer Patients. in Journal of Medical Biochemistry, 32(4).
https://doi.org/10.2478/jomb-2014-0005

Tanić N, Milinković V, Dramićanin T, Nedeljković M, Stanković T, Milovanović ZM, Šušnjar S, Milošević V, Šošić-Jurjević B, Džodić RR, Tanić N. Amplification of Cycline D1, C-Myc and Egfr Oncogenes in Tumour Samples of Breast Cancer Patients. in Journal of Medical Biochemistry. 2013;32(4).
doi:10.2478/jomb-2014-0005 .

Tanić, Nasta, Milinković, Vedrana, Dramićanin, Tatjana, Nedeljković, Milica, Stanković, Tijana, Milovanović, Zorka M., Šušnjar, Snežana, Milošević, Verica, Šošić-Jurjević, Branka, Džodić, Radan R., Tanić, Nikola, "Amplification of Cycline D1, C-Myc and Egfr Oncogenes in Tumour Samples of Breast Cancer Patients" in Journal of Medical Biochemistry, 32, no. 4 (2013),
https://doi.org/10.2478/jomb-2014-0005 . .

TY  - JOUR
AU  - Tanić, Nasta
AU  - Milašin, Jelena
AU  - Dramićanin, Tatjana
AU  - Bošković, Maja
AU  - Vukadinovic, Miroslav
AU  - Milošević, Verica
AU  - Tanić, Nikola
PY  - 2013
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/5747
AB  - Background: Head and neck squamous cell carcinoma, including oral cancer, is the sixth most common cancer worldwide. Despite advances in surgery and treatment, the 5-year survival rate has not improved significantly. There fore, reliable molecular markers for oral cancer progression are badly needed. Methods: We conducted a copy number analysis to estimate amplification status of c-myc, cycD1 and EGFR oncogenes, mutational PCR-SSCP analysis to determine activation of H-ras oncogene and inactivation of TP53 tumour suppressor gene and methylation specific PCR analysis to evaluate hypermethylation of p16 and MGMT genes. Results: c-myc oncogene was amplified in 56.7%, cycD1 in 20% and EGFR in 16.7% of Oral Squamous Cell Carcinoma (OSCC) cases while H-ras was activated in 33.3% of samples. Amplification of c-myc was significantly associated with the tumour grade 2. Interestingly, EGFR and H-ras alterations were mutually exclusive. p16 and MGMT were inactivated by hypermethylation in 30% and 13.3% of cases. Co-alteration of cycD1 and p16 were not observed in any of the analyzed samples. TP53 was inactivated in 56.7% of samples and was significantly associated with progression of OSCC, grade 2 and stage 2. Moreover, TP53 and c-myc oncogene were simultaneously altered in grade 2 OSCC. Conclusions: The most promising marker of OSCC progression remains the TP53 tumour suppressor, which is the most frequently mutated gene in oral cancers. Since there is synergism between TP53 and c-myc, it seems that co-alteration of these two genes could be also a good marker of OSCC progression from grade1 to grade 2 tumours.
T2  - Journal of Medical Biochemistry
T1  - TP53 AND C-MYC CO-ALTERATIONS - A HALLMARK OF ORAL CANCER PROGRESSION
VL  - 32
IS  - 4
SP  - 380
EP  - 388
DO  - 10.2478/jomb-2014-0009
ER  - 

@article{
author = "Tanić, Nasta and Milašin, Jelena and Dramićanin, Tatjana and Bošković, Maja and Vukadinovic, Miroslav and Milošević, Verica and Tanić, Nikola",
year = "2013",
abstract = "Background: Head and neck squamous cell carcinoma, including oral cancer, is the sixth most common cancer worldwide. Despite advances in surgery and treatment, the 5-year survival rate has not improved significantly. There fore, reliable molecular markers for oral cancer progression are badly needed. Methods: We conducted a copy number analysis to estimate amplification status of c-myc, cycD1 and EGFR oncogenes, mutational PCR-SSCP analysis to determine activation of H-ras oncogene and inactivation of TP53 tumour suppressor gene and methylation specific PCR analysis to evaluate hypermethylation of p16 and MGMT genes. Results: c-myc oncogene was amplified in 56.7%, cycD1 in 20% and EGFR in 16.7% of Oral Squamous Cell Carcinoma (OSCC) cases while H-ras was activated in 33.3% of samples. Amplification of c-myc was significantly associated with the tumour grade 2. Interestingly, EGFR and H-ras alterations were mutually exclusive. p16 and MGMT were inactivated by hypermethylation in 30% and 13.3% of cases. Co-alteration of cycD1 and p16 were not observed in any of the analyzed samples. TP53 was inactivated in 56.7% of samples and was significantly associated with progression of OSCC, grade 2 and stage 2. Moreover, TP53 and c-myc oncogene were simultaneously altered in grade 2 OSCC. Conclusions: The most promising marker of OSCC progression remains the TP53 tumour suppressor, which is the most frequently mutated gene in oral cancers. Since there is synergism between TP53 and c-myc, it seems that co-alteration of these two genes could be also a good marker of OSCC progression from grade1 to grade 2 tumours.",
journal = "Journal of Medical Biochemistry",
title = "TP53 AND C-MYC CO-ALTERATIONS - A HALLMARK OF ORAL CANCER PROGRESSION",
volume = "32",
number = "4",
pages = "380-388",
doi = "10.2478/jomb-2014-0009"
}

Tanić, N., Milašin, J., Dramićanin, T., Bošković, M., Vukadinovic, M., Milošević, V.,& Tanić, N.. (2013). TP53 AND C-MYC CO-ALTERATIONS - A HALLMARK OF ORAL CANCER PROGRESSION. in Journal of Medical Biochemistry, 32(4), 380-388.
https://doi.org/10.2478/jomb-2014-0009

Tanić N, Milašin J, Dramićanin T, Bošković M, Vukadinovic M, Milošević V, Tanić N. TP53 AND C-MYC CO-ALTERATIONS - A HALLMARK OF ORAL CANCER PROGRESSION. in Journal of Medical Biochemistry. 2013;32(4):380-388.
doi:10.2478/jomb-2014-0009 .

Tanić, Nasta, Milašin, Jelena, Dramićanin, Tatjana, Bošković, Maja, Vukadinovic, Miroslav, Milošević, Verica, Tanić, Nikola, "TP53 AND C-MYC CO-ALTERATIONS - A HALLMARK OF ORAL CANCER PROGRESSION" in Journal of Medical Biochemistry, 32, no. 4 (2013):380-388,
https://doi.org/10.2478/jomb-2014-0009 . .

TY  - JOUR
AU  - Lenhardt, Lea I.
AU  - Zeković, Ivana Lj.
AU  - Dramićanin, Tatjana
AU  - Dramićanin, Miroslav
PY  - 2013
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/7026
AB  - Over the years various optical spectroscopic techniques have been widely used as diagnostic tools in the discrimination of many types of malignant diseases. Recently, synchronous fluorescent spectroscopy (SFS) coupled with chemometrics has been applied in cancer diagnostics. The SFS method involves simultaneous scanning of both emission and excitation wavelengths while keeping the interval of wavelengths (constant-wavelength mode) or frequencies (constant-energy mode) between them constant. This method is fast, relatively inexpensive, sensitive and non-invasive. Total synchronous fluorescence spectra of normal skin, nevus and melanoma samples were used as input for training of artificial neural networks. Two different types of artificial neural networks were trained, the self-organizing map and the feed-forward neural network. Histopathology results of investigated skin samples were used as the gold standard for network output. Based on the obtained classification success rate of neural networks, we concluded that both networks provided high sensitivity with classification errors between 2 and 4%.
T2  - Physica Scripta
T1  - Artificial neural networks for processing fluorescence spectroscopy data in skin cancer diagnostics
VL  - T157
DO  - 10.1088/0031-8949/2013/T157/014057
ER  - 

@article{
author = "Lenhardt, Lea I. and Zeković, Ivana Lj. and Dramićanin, Tatjana and Dramićanin, Miroslav",
year = "2013",
abstract = "Over the years various optical spectroscopic techniques have been widely used as diagnostic tools in the discrimination of many types of malignant diseases. Recently, synchronous fluorescent spectroscopy (SFS) coupled with chemometrics has been applied in cancer diagnostics. The SFS method involves simultaneous scanning of both emission and excitation wavelengths while keeping the interval of wavelengths (constant-wavelength mode) or frequencies (constant-energy mode) between them constant. This method is fast, relatively inexpensive, sensitive and non-invasive. Total synchronous fluorescence spectra of normal skin, nevus and melanoma samples were used as input for training of artificial neural networks. Two different types of artificial neural networks were trained, the self-organizing map and the feed-forward neural network. Histopathology results of investigated skin samples were used as the gold standard for network output. Based on the obtained classification success rate of neural networks, we concluded that both networks provided high sensitivity with classification errors between 2 and 4%.",
journal = "Physica Scripta",
title = "Artificial neural networks for processing fluorescence spectroscopy data in skin cancer diagnostics",
volume = "T157",
doi = "10.1088/0031-8949/2013/T157/014057"
}

Lenhardt, L. I., Zeković, I. Lj., Dramićanin, T.,& Dramićanin, M.. (2013). Artificial neural networks for processing fluorescence spectroscopy data in skin cancer diagnostics. in Physica Scripta, T157.
https://doi.org/10.1088/0031-8949/2013/T157/014057

Lenhardt LI, Zeković IL, Dramićanin T, Dramićanin M. Artificial neural networks for processing fluorescence spectroscopy data in skin cancer diagnostics. in Physica Scripta. 2013;T157.
doi:10.1088/0031-8949/2013/T157/014057 .

Lenhardt, Lea I., Zeković, Ivana Lj., Dramićanin, Tatjana, Dramićanin, Miroslav, "Artificial neural networks for processing fluorescence spectroscopy data in skin cancer diagnostics" in Physica Scripta, T157 (2013),
https://doi.org/10.1088/0031-8949/2013/T157/014057 . .

TY  - JOUR
AU  - Tanić, Nikola
AU  - Milovanović, Zorka M.
AU  - Tanić, Nasta
AU  - Džodić, Radan R.
AU  - Juranic, Zorica
AU  - Šušnjar, Snežana
AU  - Plesinac-Karapandzic, Vesna
AU  - Tatic, Svetislav
AU  - Dramićanin, Tatjana
AU  - Davidović, Radoslav S.
AU  - Dimitrijević, Bogomir B.
PY  - 2012
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/5073
AB  - Tamoxifen is a standard therapeutical treatment in patients with estrogen receptor positive breast carcinoma. However, less than 50% of estrogen receptor positive breast cancers do not respond to tamoxifen treatment whereas 40% of tumors that initially respond to treatment develop resistance over time. The underlying mechanisms for tamoxifen resistance are probably multifactorial but remain largely unknown. The primary aim of this study was to investigate the impact of PTEN tumor suppressor gene on acquiring resistance to tamoxifen by analyzing loss of heterozygosity (LOH) and immunohystochemical expression of PTEN in 49 primary breast carcinomas of patients treated with tamoxifen as the only adjuvant therapy. The effect of PTEN inactivation on breast cancer progression and disease outcome was also analyzed. Reduced or completely lost PTEN expression was observed in 55.1% of samples, while 63.3% of samples displayed LOH of PTEN gene. Inactivation of PTEN immunoexpression significantly correlated with the PTEN loss of heterozygosity, suggesting LOH as the most important genetic mechanism for the reduction or complete loss of PTEN expression in primary breast carcinoma. Most importantly, LOH of PTEN and consequential reduction of its immunoexpression showed significant correlation with the recurrence of the disease. Besides, our study revealed that LOH of PTEN tumor suppressor was significantly associated with shorter disease free survival, breast cancer specific survival and overall survival. In summary, our results imply that LOH of PTEN could be used as a good prognostic characteristic for the outcome of breast cancer patients treated with tamoxifen.
T2  - Cancer Biology and Therapy
T1  - The impact of PTEN tumor suppressor gene on acquiring resistance to tamoxifen treatment in breast cancer patients
VL  - 13
IS  - 12
SP  - 1165
EP  - 1174
DO  - 10.4161/cbt.21346
ER  - 

@article{
author = "Tanić, Nikola and Milovanović, Zorka M. and Tanić, Nasta and Džodić, Radan R. and Juranic, Zorica and Šušnjar, Snežana and Plesinac-Karapandzic, Vesna and Tatic, Svetislav and Dramićanin, Tatjana and Davidović, Radoslav S. and Dimitrijević, Bogomir B.",
year = "2012",
abstract = "Tamoxifen is a standard therapeutical treatment in patients with estrogen receptor positive breast carcinoma. However, less than 50% of estrogen receptor positive breast cancers do not respond to tamoxifen treatment whereas 40% of tumors that initially respond to treatment develop resistance over time. The underlying mechanisms for tamoxifen resistance are probably multifactorial but remain largely unknown. The primary aim of this study was to investigate the impact of PTEN tumor suppressor gene on acquiring resistance to tamoxifen by analyzing loss of heterozygosity (LOH) and immunohystochemical expression of PTEN in 49 primary breast carcinomas of patients treated with tamoxifen as the only adjuvant therapy. The effect of PTEN inactivation on breast cancer progression and disease outcome was also analyzed. Reduced or completely lost PTEN expression was observed in 55.1% of samples, while 63.3% of samples displayed LOH of PTEN gene. Inactivation of PTEN immunoexpression significantly correlated with the PTEN loss of heterozygosity, suggesting LOH as the most important genetic mechanism for the reduction or complete loss of PTEN expression in primary breast carcinoma. Most importantly, LOH of PTEN and consequential reduction of its immunoexpression showed significant correlation with the recurrence of the disease. Besides, our study revealed that LOH of PTEN tumor suppressor was significantly associated with shorter disease free survival, breast cancer specific survival and overall survival. In summary, our results imply that LOH of PTEN could be used as a good prognostic characteristic for the outcome of breast cancer patients treated with tamoxifen.",
journal = "Cancer Biology and Therapy",
title = "The impact of PTEN tumor suppressor gene on acquiring resistance to tamoxifen treatment in breast cancer patients",
volume = "13",
number = "12",
pages = "1165-1174",
doi = "10.4161/cbt.21346"
}

Tanić, N., Milovanović, Z. M., Tanić, N., Džodić, R. R., Juranic, Z., Šušnjar, S., Plesinac-Karapandzic, V., Tatic, S., Dramićanin, T., Davidović, R. S.,& Dimitrijević, B. B.. (2012). The impact of PTEN tumor suppressor gene on acquiring resistance to tamoxifen treatment in breast cancer patients. in Cancer Biology and Therapy, 13(12), 1165-1174.
https://doi.org/10.4161/cbt.21346

Tanić N, Milovanović ZM, Tanić N, Džodić RR, Juranic Z, Šušnjar S, Plesinac-Karapandzic V, Tatic S, Dramićanin T, Davidović RS, Dimitrijević BB. The impact of PTEN tumor suppressor gene on acquiring resistance to tamoxifen treatment in breast cancer patients. in Cancer Biology and Therapy. 2012;13(12):1165-1174.
doi:10.4161/cbt.21346 .

Tanić, Nikola, Milovanović, Zorka M., Tanić, Nasta, Džodić, Radan R., Juranic, Zorica, Šušnjar, Snežana, Plesinac-Karapandzic, Vesna, Tatic, Svetislav, Dramićanin, Tatjana, Davidović, Radoslav S., Dimitrijević, Bogomir B., "The impact of PTEN tumor suppressor gene on acquiring resistance to tamoxifen treatment in breast cancer patients" in Cancer Biology and Therapy, 13, no. 12 (2012):1165-1174,
https://doi.org/10.4161/cbt.21346 . .

TY  - JOUR
AU  - Dramićanin, Tatjana
AU  - Lenhardt, Lea I.
AU  - Zeković, Ivana Lj.
AU  - Dramićanin, Miroslav
PY  - 2012
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/5020
AB  - Excitation-emission matrices (EEM) and total synchronous fluorescence spectra (SFS) of normal and malignant breast tissue specimens are measured in UV-VIS spectral region to serve as data inputs in development of Support Vector Machine (SVM) based breast cancer diagnostics tool. Various input data combinations are tested for classification accuracy using SVM prediction against histopathology findings to discover the best combination regarding diagnostics sensitivity and specificity. It is shown that with EEM data SVM provided 67 % sensitivity and 62 % specificity diagnostics. With SFS data SVM provided 100 % sensitivity and specificity for a several input data combinations. Among these combinations those that require minimal data inputs are identified.
T2  - Journal of Fluorescence
T1  - Support Vector Machine on Fluorescence Landscapes for Breast Cancer Diagnostics
VL  - 22
IS  - 5
SP  - 1281
EP  - 1289
DO  - 10.1007/s10895-012-1070-0
ER  - 

@article{
author = "Dramićanin, Tatjana and Lenhardt, Lea I. and Zeković, Ivana Lj. and Dramićanin, Miroslav",
year = "2012",
abstract = "Excitation-emission matrices (EEM) and total synchronous fluorescence spectra (SFS) of normal and malignant breast tissue specimens are measured in UV-VIS spectral region to serve as data inputs in development of Support Vector Machine (SVM) based breast cancer diagnostics tool. Various input data combinations are tested for classification accuracy using SVM prediction against histopathology findings to discover the best combination regarding diagnostics sensitivity and specificity. It is shown that with EEM data SVM provided 67 % sensitivity and 62 % specificity diagnostics. With SFS data SVM provided 100 % sensitivity and specificity for a several input data combinations. Among these combinations those that require minimal data inputs are identified.",
journal = "Journal of Fluorescence",
title = "Support Vector Machine on Fluorescence Landscapes for Breast Cancer Diagnostics",
volume = "22",
number = "5",
pages = "1281-1289",
doi = "10.1007/s10895-012-1070-0"
}

Dramićanin, T., Lenhardt, L. I., Zeković, I. Lj.,& Dramićanin, M.. (2012). Support Vector Machine on Fluorescence Landscapes for Breast Cancer Diagnostics. in Journal of Fluorescence, 22(5), 1281-1289.
https://doi.org/10.1007/s10895-012-1070-0

Dramićanin T, Lenhardt LI, Zeković IL, Dramićanin M. Support Vector Machine on Fluorescence Landscapes for Breast Cancer Diagnostics. in Journal of Fluorescence. 2012;22(5):1281-1289.
doi:10.1007/s10895-012-1070-0 .

Dramićanin, Tatjana, Lenhardt, Lea I., Zeković, Ivana Lj., Dramićanin, Miroslav, "Support Vector Machine on Fluorescence Landscapes for Breast Cancer Diagnostics" in Journal of Fluorescence, 22, no. 5 (2012):1281-1289,
https://doi.org/10.1007/s10895-012-1070-0 . .

TY  - JOUR
AU  - Zeković, Ivana Lj.
AU  - Lenhardt, Lea I.
AU  - Dramićanin, Tatjana
AU  - Dramićanin, Miroslav
PY  - 2012
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/5027
AB  - Synchronous fluorescence spectroscopy, a technique that measures both the absorption and the emission properties of a sample in a single measurement, was used for the analysis and classification of intact cereal flours (wheat, corn, rye, buckwheat, rice, and barley). Total synchronous fluorescence spectra recorded in constant wavelength mode show clear differences in the emission spectra of different flours due to variances in intrinsic fluorophore concentrations and their microenvironments. Principal component analysis, cluster analysis, and partial least squares discriminant analysis are used to assess the ability of synchronous fluorescence measurements to differentiate and classify intact samples of different flour types. The flour specimens were obtained directly from a market in Belgrade and had different expiration dates to provide a more representative set of samples. The results of the current analysis suggest that chemometric methods applied on synchronous fluorescence data can discriminate and classify flour types and that the best results are achieved using a combination of synchronous fluorescence measurements at synchronous intervals of 7 and 20 nm. The quality of results, the high speed of measurements, and the avoidance of extensive sample preparation make synchronous fluorescence spectroscopy a promising technique for cereal research.
T2  - Food Analytical Methods
T1  - Classification of Intact Cereal Flours by Front-Face Synchronous Fluorescence Spectroscopy
VL  - 5
IS  - 5
SP  - 1205
EP  - 1213
DO  - 10.1007/s12161-011-9359-1
ER  - 

@article{
author = "Zeković, Ivana Lj. and Lenhardt, Lea I. and Dramićanin, Tatjana and Dramićanin, Miroslav",
year = "2012",
abstract = "Synchronous fluorescence spectroscopy, a technique that measures both the absorption and the emission properties of a sample in a single measurement, was used for the analysis and classification of intact cereal flours (wheat, corn, rye, buckwheat, rice, and barley). Total synchronous fluorescence spectra recorded in constant wavelength mode show clear differences in the emission spectra of different flours due to variances in intrinsic fluorophore concentrations and their microenvironments. Principal component analysis, cluster analysis, and partial least squares discriminant analysis are used to assess the ability of synchronous fluorescence measurements to differentiate and classify intact samples of different flour types. The flour specimens were obtained directly from a market in Belgrade and had different expiration dates to provide a more representative set of samples. The results of the current analysis suggest that chemometric methods applied on synchronous fluorescence data can discriminate and classify flour types and that the best results are achieved using a combination of synchronous fluorescence measurements at synchronous intervals of 7 and 20 nm. The quality of results, the high speed of measurements, and the avoidance of extensive sample preparation make synchronous fluorescence spectroscopy a promising technique for cereal research.",
journal = "Food Analytical Methods",
title = "Classification of Intact Cereal Flours by Front-Face Synchronous Fluorescence Spectroscopy",
volume = "5",
number = "5",
pages = "1205-1213",
doi = "10.1007/s12161-011-9359-1"
}

Zeković, I. Lj., Lenhardt, L. I., Dramićanin, T.,& Dramićanin, M.. (2012). Classification of Intact Cereal Flours by Front-Face Synchronous Fluorescence Spectroscopy. in Food Analytical Methods, 5(5), 1205-1213.
https://doi.org/10.1007/s12161-011-9359-1

Zeković IL, Lenhardt LI, Dramićanin T, Dramićanin M. Classification of Intact Cereal Flours by Front-Face Synchronous Fluorescence Spectroscopy. in Food Analytical Methods. 2012;5(5):1205-1213.
doi:10.1007/s12161-011-9359-1 .

Zeković, Ivana Lj., Lenhardt, Lea I., Dramićanin, Tatjana, Dramićanin, Miroslav, "Classification of Intact Cereal Flours by Front-Face Synchronous Fluorescence Spectroscopy" in Food Analytical Methods, 5, no. 5 (2012):1205-1213,
https://doi.org/10.1007/s12161-011-9359-1 . .

TY  - JOUR
AU  - Dramićanin, Tatjana
AU  - Dimitrijević, Bogomir B.
AU  - Dramićanin, Miroslav
PY  - 2011
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/4235
AB  - Data from total synchronous fluorescence spectroscopy (TSFS) measurements of normal and malignant breast tissue samples are introduced in supervised self-organizing maps, a type of artificial neural network (ANN), to obtain diagnosis. Three spectral regions in both TSFS patterns and first-derivative TSFS patterns exhibited clear differences between normal and malignant tissue groups, and intensities measured from these regions served as inputs to neural networks. Histology findings are used as the gold standard to train self-organizing maps in a supervised way. Diagnostic accuracy of this procedure is evaluated with sample test groups for two cases, when the neural network uses TSFS data and when the neural network uses data from first-derivative TSFS. In the first case diagnostic sensitivity of 87.1% and specificity of 91.7% are found, while in the second case sensitivity of 100% and specificity of 94.4% are achieved.
T2  - Applied Spectroscopy
T1  - Application of Supervised Self-Organizing Maps in Breast Cancer Diagnosis by Total Synchronous Fluorescence Spectroscopy
VL  - 65
IS  - 3
SP  - 293
EP  - 297
DO  - 10.1366/10-05928
ER  - 

@article{
author = "Dramićanin, Tatjana and Dimitrijević, Bogomir B. and Dramićanin, Miroslav",
year = "2011",
abstract = "Data from total synchronous fluorescence spectroscopy (TSFS) measurements of normal and malignant breast tissue samples are introduced in supervised self-organizing maps, a type of artificial neural network (ANN), to obtain diagnosis. Three spectral regions in both TSFS patterns and first-derivative TSFS patterns exhibited clear differences between normal and malignant tissue groups, and intensities measured from these regions served as inputs to neural networks. Histology findings are used as the gold standard to train self-organizing maps in a supervised way. Diagnostic accuracy of this procedure is evaluated with sample test groups for two cases, when the neural network uses TSFS data and when the neural network uses data from first-derivative TSFS. In the first case diagnostic sensitivity of 87.1% and specificity of 91.7% are found, while in the second case sensitivity of 100% and specificity of 94.4% are achieved.",
journal = "Applied Spectroscopy",
title = "Application of Supervised Self-Organizing Maps in Breast Cancer Diagnosis by Total Synchronous Fluorescence Spectroscopy",
volume = "65",
number = "3",
pages = "293-297",
doi = "10.1366/10-05928"
}

Dramićanin, T., Dimitrijević, B. B.,& Dramićanin, M.. (2011). Application of Supervised Self-Organizing Maps in Breast Cancer Diagnosis by Total Synchronous Fluorescence Spectroscopy. in Applied Spectroscopy, 65(3), 293-297.
https://doi.org/10.1366/10-05928

Dramićanin T, Dimitrijević BB, Dramićanin M. Application of Supervised Self-Organizing Maps in Breast Cancer Diagnosis by Total Synchronous Fluorescence Spectroscopy. in Applied Spectroscopy. 2011;65(3):293-297.
doi:10.1366/10-05928 .

Dramićanin, Tatjana, Dimitrijević, Bogomir B., Dramićanin, Miroslav, "Application of Supervised Self-Organizing Maps in Breast Cancer Diagnosis by Total Synchronous Fluorescence Spectroscopy" in Applied Spectroscopy, 65, no. 3 (2011):293-297,
https://doi.org/10.1366/10-05928 . .

TY  - JOUR
AU  - Dramićanin, Tatjana
AU  - Zeković, Ivana Lj.
AU  - Dimitrijević, Bogomir B.
AU  - Ribar, Srđan
AU  - Dramićanin, Miroslav
PY  - 2009
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/6848
AB  - Supervised self-organizing map, a type of artificial neural network, is applied for classification of human breast tissue samples utilizing data obtained from fluorescence landscape measurements. Female breast tissue samples were taken soon after the surgical resection, identified and stored at -80 degrees C until fluorescence measurements. From fluorescence landscapes obtained in UV-VIS region spectral features showing statistically significant differences between malignant and normal samples are identified and further quantified to serve as a training input to neural network. Additional set of samples was used as a test group input to trained network in order to evaluate performance of proposed optical biopsy method. Classification sensitivity of 83.9% and specificity of 88.9% are found.
T2  - Acta Physica Polonica A
T1  - Optical Biopsy Method for Breast Cancer Diagnosis Based on Artificial Neural Network Classification of Fluorescence Landscape Data
VL  - 116
IS  - 4
SP  - 690
EP  - 692
DO  - 10.12693/APhysPolA.116.690
ER  - 

@article{
author = "Dramićanin, Tatjana and Zeković, Ivana Lj. and Dimitrijević, Bogomir B. and Ribar, Srđan and Dramićanin, Miroslav",
year = "2009",
abstract = "Supervised self-organizing map, a type of artificial neural network, is applied for classification of human breast tissue samples utilizing data obtained from fluorescence landscape measurements. Female breast tissue samples were taken soon after the surgical resection, identified and stored at -80 degrees C until fluorescence measurements. From fluorescence landscapes obtained in UV-VIS region spectral features showing statistically significant differences between malignant and normal samples are identified and further quantified to serve as a training input to neural network. Additional set of samples was used as a test group input to trained network in order to evaluate performance of proposed optical biopsy method. Classification sensitivity of 83.9% and specificity of 88.9% are found.",
journal = "Acta Physica Polonica A",
title = "Optical Biopsy Method for Breast Cancer Diagnosis Based on Artificial Neural Network Classification of Fluorescence Landscape Data",
volume = "116",
number = "4",
pages = "690-692",
doi = "10.12693/APhysPolA.116.690"
}

Dramićanin, T., Zeković, I. Lj., Dimitrijević, B. B., Ribar, S.,& Dramićanin, M.. (2009). Optical Biopsy Method for Breast Cancer Diagnosis Based on Artificial Neural Network Classification of Fluorescence Landscape Data. in Acta Physica Polonica A, 116(4), 690-692.
https://doi.org/10.12693/APhysPolA.116.690

Dramićanin T, Zeković IL, Dimitrijević BB, Ribar S, Dramićanin M. Optical Biopsy Method for Breast Cancer Diagnosis Based on Artificial Neural Network Classification of Fluorescence Landscape Data. in Acta Physica Polonica A. 2009;116(4):690-692.
doi:10.12693/APhysPolA.116.690 .

Dramićanin, Tatjana, Zeković, Ivana Lj., Dimitrijević, Bogomir B., Ribar, Srđan, Dramićanin, Miroslav, "Optical Biopsy Method for Breast Cancer Diagnosis Based on Artificial Neural Network Classification of Fluorescence Landscape Data" in Acta Physica Polonica A, 116, no. 4 (2009):690-692,
https://doi.org/10.12693/APhysPolA.116.690 . .

TY  - JOUR
AU  - Antić, Željka
AU  - Krsmanović, Radenka
AU  - Đorđević, Vesna R.
AU  - Dramićanin, Tatjana
AU  - Dramićanin, Miroslav
PY  - 2009
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/6846
AB  - In the present work we explored the possibility of obtaining Y2O3:Eu3+ mu m-size particles by an ultrasonic spray pyrolysis method. As-prepared sample constitutes of spherical, hollow particles with an average size of 1 to 2 mu m. Pure, well crystalline, cubic Y2O3 is formed after additional thermal treatment at 800 degrees C for 2 h. A detailed optical investigation has been done with photoluminescence measurements in the energy and time domains. Experimental intensity parameters, transition rates and quantum efficiency of the D-5(0) emission are evaluated on the basis of Judd-Ofelt theory.
T2  - Acta Physica Polonica A
T1  - Optical Properties of Y2O3:Eu3+ Red Emitting Phosphor Obtained via Spray Pyrolysis
VL  - 116
IS  - 4
SP  - 622
EP  - 624
DO  - 10.12693/APhysPolA.116.622
UR  - https://hdl.handle.net/21.15107/rcub_vinar_6846
ER  - 

@article{
author = "Antić, Željka and Krsmanović, Radenka and Đorđević, Vesna R. and Dramićanin, Tatjana and Dramićanin, Miroslav",
year = "2009",
abstract = "In the present work we explored the possibility of obtaining Y2O3:Eu3+ mu m-size particles by an ultrasonic spray pyrolysis method. As-prepared sample constitutes of spherical, hollow particles with an average size of 1 to 2 mu m. Pure, well crystalline, cubic Y2O3 is formed after additional thermal treatment at 800 degrees C for 2 h. A detailed optical investigation has been done with photoluminescence measurements in the energy and time domains. Experimental intensity parameters, transition rates and quantum efficiency of the D-5(0) emission are evaluated on the basis of Judd-Ofelt theory.",
journal = "Acta Physica Polonica A",
title = "Optical Properties of Y2O3:Eu3+ Red Emitting Phosphor Obtained via Spray Pyrolysis",
volume = "116",
number = "4",
pages = "622-624",
doi = "10.12693/APhysPolA.116.622",
url = "https://hdl.handle.net/21.15107/rcub_vinar_6846"
}

Antić, Ž., Krsmanović, R., Đorđević, V. R., Dramićanin, T.,& Dramićanin, M.. (2009). Optical Properties of Y2O3:Eu3+ Red Emitting Phosphor Obtained via Spray Pyrolysis. in Acta Physica Polonica A, 116(4), 622-624.
https://doi.org/10.12693/APhysPolA.116.622
https://hdl.handle.net/21.15107/rcub_vinar_6846

Antić Ž, Krsmanović R, Đorđević VR, Dramićanin T, Dramićanin M. Optical Properties of Y2O3:Eu3+ Red Emitting Phosphor Obtained via Spray Pyrolysis. in Acta Physica Polonica A. 2009;116(4):622-624.
doi:10.12693/APhysPolA.116.622
https://hdl.handle.net/21.15107/rcub_vinar_6846 .

Antić, Željka, Krsmanović, Radenka, Đorđević, Vesna R., Dramićanin, Tatjana, Dramićanin, Miroslav, "Optical Properties of Y2O3:Eu3+ Red Emitting Phosphor Obtained via Spray Pyrolysis" in Acta Physica Polonica A, 116, no. 4 (2009):622-624,
https://doi.org/10.12693/APhysPolA.116.622 .,
https://hdl.handle.net/21.15107/rcub_vinar_6846 .

TY  - JOUR
AU  - Jokanović, Vukoman R.
AU  - Dramićanin, Miroslav
AU  - Andrić, Željka
AU  - Dramićanin, Tatjana
AU  - Plavsic, M.
AU  - Pašalić, Snežana
AU  - Miljkovic, M.
PY  - 2008
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/6732
AB  - A new approach to the two-level design and self-assembling of Me(x)SiO(y) (Me = Gd, Y and Ca or their mixtures) nano-powders from SiO(2) sols is described. The nanostructure design of various optical active materials based on different compounds of Me(x)Sio(y) is discussed. These particles were formed by the combination of hydrothermal synthesis and ultrasound spray pyrolysis. The morphology and structural design of the particles and sub-particles are defined by their synthesis procedure and processing parameters. The mean particle size and size distribution of all the Me(x)SiO(y) based compounds were determined by SEM analysis. These results were compared with the particle diameter evaluated from the theoretical model of the breaking-up of capillary waves. For all the synthesized powders, the obtained results indicate the possibility of a rigorous design of the structure of the particles throughout their entire hierarchy. (c) 2007 Elsevier B.V. All rights reserved.
T2  - Optical Materials
T1  - Nanostructure designed powders of optical active materials Me(x)SiO(y) obtained by ultrasonic spray pyrolysis
VL  - 30
IS  - 7
SP  - 1168
EP  - 1172
DO  - 10.1016/j.optmat.2007.05.043
ER  - 

@article{
author = "Jokanović, Vukoman R. and Dramićanin, Miroslav and Andrić, Željka and Dramićanin, Tatjana and Plavsic, M. and Pašalić, Snežana and Miljkovic, M.",
year = "2008",
abstract = "A new approach to the two-level design and self-assembling of Me(x)SiO(y) (Me = Gd, Y and Ca or their mixtures) nano-powders from SiO(2) sols is described. The nanostructure design of various optical active materials based on different compounds of Me(x)Sio(y) is discussed. These particles were formed by the combination of hydrothermal synthesis and ultrasound spray pyrolysis. The morphology and structural design of the particles and sub-particles are defined by their synthesis procedure and processing parameters. The mean particle size and size distribution of all the Me(x)SiO(y) based compounds were determined by SEM analysis. These results were compared with the particle diameter evaluated from the theoretical model of the breaking-up of capillary waves. For all the synthesized powders, the obtained results indicate the possibility of a rigorous design of the structure of the particles throughout their entire hierarchy. (c) 2007 Elsevier B.V. All rights reserved.",
journal = "Optical Materials",
title = "Nanostructure designed powders of optical active materials Me(x)SiO(y) obtained by ultrasonic spray pyrolysis",
volume = "30",
number = "7",
pages = "1168-1172",
doi = "10.1016/j.optmat.2007.05.043"
}

Jokanović, V. R., Dramićanin, M., Andrić, Ž., Dramićanin, T., Plavsic, M., Pašalić, S.,& Miljkovic, M.. (2008). Nanostructure designed powders of optical active materials Me(x)SiO(y) obtained by ultrasonic spray pyrolysis. in Optical Materials, 30(7), 1168-1172.
https://doi.org/10.1016/j.optmat.2007.05.043

Jokanović VR, Dramićanin M, Andrić Ž, Dramićanin T, Plavsic M, Pašalić S, Miljkovic M. Nanostructure designed powders of optical active materials Me(x)SiO(y) obtained by ultrasonic spray pyrolysis. in Optical Materials. 2008;30(7):1168-1172.
doi:10.1016/j.optmat.2007.05.043 .

Jokanović, Vukoman R., Dramićanin, Miroslav, Andrić, Željka, Dramićanin, Tatjana, Plavsic, M., Pašalić, Snežana, Miljkovic, M., "Nanostructure designed powders of optical active materials Me(x)SiO(y) obtained by ultrasonic spray pyrolysis" in Optical Materials, 30, no. 7 (2008):1168-1172,
https://doi.org/10.1016/j.optmat.2007.05.043 . .