TY  - JOUR
AU  - Vukoje, Ivana
AU  - Lazić, Vesna M.
AU  - Sredojević, Dušan
AU  - Fernandes, Margarida M.
AU  - Lanceros-Mendez, Senentxu
AU  - Ahrenkiel, S. Phillip
AU  - Nedeljković, Jovan
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10052
AB  - Aqueous colloids, consisting of 15–30 nm-sized silver nanoparticles (Ag NPs), were prepared using the reducing and stabilizing abilities of glucose, sucrose, and dextran. The long-term stability of coated Ag NPs increases from glucose over sucrose to dextran, i.e., with the increase of the molecular weight of carbohydrate molecules. The density functional theory (DFT) calculations of the partial atomic (Mulliken) charges and adsorption energies are applied to explain the enhanced stability of coated Ag NPs. All coated Ag NPs have a significantly broader concentration range of nontoxic behavior toward pre-osteoblast cells than bare Ag NPs prepared using sodium borohydride. The carbohydrate-coated Ag NPs display the same level of toxic ability against Gram-negative (Escherichia coli) and Gram-positive (Staphylococcus aureus) bacteria as bare Ag NPs. The differences in toxicity mechanism of the coated and bare Ag NPs are a consequence of the absence and presence of co-occurring Ag+ ions in examined dispersion, respectively.
T2  - International Journal of Biological Macromolecules
T2  - International Journal of Biological MacromoleculesInternational Journal of Biological Macromolecules
T1  - Influence of glucose, sucrose, and dextran coatings on the stability and toxicity of silver nanoparticles
VL  - 194
SP  - 461
EP  - 469
DO  - 10.1016/j.ijbiomac.2021.11.089
ER  - 

@article{
author = "Vukoje, Ivana and Lazić, Vesna M. and Sredojević, Dušan and Fernandes, Margarida M. and Lanceros-Mendez, Senentxu and Ahrenkiel, S. Phillip and Nedeljković, Jovan",
year = "2022",
abstract = "Aqueous colloids, consisting of 15–30 nm-sized silver nanoparticles (Ag NPs), were prepared using the reducing and stabilizing abilities of glucose, sucrose, and dextran. The long-term stability of coated Ag NPs increases from glucose over sucrose to dextran, i.e., with the increase of the molecular weight of carbohydrate molecules. The density functional theory (DFT) calculations of the partial atomic (Mulliken) charges and adsorption energies are applied to explain the enhanced stability of coated Ag NPs. All coated Ag NPs have a significantly broader concentration range of nontoxic behavior toward pre-osteoblast cells than bare Ag NPs prepared using sodium borohydride. The carbohydrate-coated Ag NPs display the same level of toxic ability against Gram-negative (Escherichia coli) and Gram-positive (Staphylococcus aureus) bacteria as bare Ag NPs. The differences in toxicity mechanism of the coated and bare Ag NPs are a consequence of the absence and presence of co-occurring Ag+ ions in examined dispersion, respectively.",
journal = "International Journal of Biological Macromolecules, International Journal of Biological MacromoleculesInternational Journal of Biological Macromolecules",
title = "Influence of glucose, sucrose, and dextran coatings on the stability and toxicity of silver nanoparticles",
volume = "194",
pages = "461-469",
doi = "10.1016/j.ijbiomac.2021.11.089"
}

Vukoje, I., Lazić, V. M., Sredojević, D., Fernandes, M. M., Lanceros-Mendez, S., Ahrenkiel, S. P.,& Nedeljković, J.. (2022). Influence of glucose, sucrose, and dextran coatings on the stability and toxicity of silver nanoparticles. in International Journal of Biological Macromolecules, 194, 461-469.
https://doi.org/10.1016/j.ijbiomac.2021.11.089

Vukoje I, Lazić VM, Sredojević D, Fernandes MM, Lanceros-Mendez S, Ahrenkiel SP, Nedeljković J. Influence of glucose, sucrose, and dextran coatings on the stability and toxicity of silver nanoparticles. in International Journal of Biological Macromolecules. 2022;194:461-469.
doi:10.1016/j.ijbiomac.2021.11.089 .

Vukoje, Ivana, Lazić, Vesna M., Sredojević, Dušan, Fernandes, Margarida M., Lanceros-Mendez, Senentxu, Ahrenkiel, S. Phillip, Nedeljković, Jovan, "Influence of glucose, sucrose, and dextran coatings on the stability and toxicity of silver nanoparticles" in International Journal of Biological Macromolecules, 194 (2022):461-469,
https://doi.org/10.1016/j.ijbiomac.2021.11.089 . .

TY  - JOUR
AU  - Lazić, Vesna M.
AU  - Pirković, Andrea
AU  - Sredojević, Dušan
AU  - Marković, Jelena P.
AU  - Papan, Jelena
AU  - Ahrenkiel, S. Phillip
AU  - Janković-Častvan, Ivona
AU  - Dekanski, Dragana
AU  - Jovanović Krivokuća, Milica
AU  - Nedeljković, Jovan
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9897
AB  - The toxicity of hybrid nanoparticles, consisting of non-toxic components, zirconium dioxide nanoparticles (ZrO2 NPs), and caffeic acid (CA), was examined against four different cell lines (HTR-8 SV/Neo, JEG-3, JAR, and HeLa). Stable aqueous ZrO2 sol, synthesized by forced hydrolysis, consists of 3–4 nm in size primary particles organized in 30–60 nm in size snowflake-like particles, as determined by transmission electron microscopy and direct light scattering measurements. The surface modification of ZrO2 NPs with CA leads to the formation of an interfacial charge transfer (ICT) complex followed by the appearance of absorption in the visible spectral range. The spectroscopic observations are complemented with the density functional theory calculations using a cluster model. The ZrO2 NPs and CA are non-toxic against four different cell lines in investigated concentration range. Also, ZrO2 NPs promote the proliferation of HTR-8 SV/Neo, JAR, and HeLa cells. On the other hand, hybrid ZrO2/CA NPs induced a significant reduction of the viability of the JEG-3 cells (39 %) for the high concentration of components (1.6 mM ZrO2 and 0.4 mM CA).
T2  - Chemico-Biological Interactions
T1  - Surface-modified ZrO2 nanoparticles with caffeic acid: Characterization and in vitro evaluation of biosafety for placental cells
VL  - 347
SP  - 109618
DO  - 10.1016/j.cbi.2021.109618
ER  - 

@article{
author = "Lazić, Vesna M. and Pirković, Andrea and Sredojević, Dušan and Marković, Jelena P. and Papan, Jelena and Ahrenkiel, S. Phillip and Janković-Častvan, Ivona and Dekanski, Dragana and Jovanović Krivokuća, Milica and Nedeljković, Jovan",
year = "2021",
abstract = "The toxicity of hybrid nanoparticles, consisting of non-toxic components, zirconium dioxide nanoparticles (ZrO2 NPs), and caffeic acid (CA), was examined against four different cell lines (HTR-8 SV/Neo, JEG-3, JAR, and HeLa). Stable aqueous ZrO2 sol, synthesized by forced hydrolysis, consists of 3–4 nm in size primary particles organized in 30–60 nm in size snowflake-like particles, as determined by transmission electron microscopy and direct light scattering measurements. The surface modification of ZrO2 NPs with CA leads to the formation of an interfacial charge transfer (ICT) complex followed by the appearance of absorption in the visible spectral range. The spectroscopic observations are complemented with the density functional theory calculations using a cluster model. The ZrO2 NPs and CA are non-toxic against four different cell lines in investigated concentration range. Also, ZrO2 NPs promote the proliferation of HTR-8 SV/Neo, JAR, and HeLa cells. On the other hand, hybrid ZrO2/CA NPs induced a significant reduction of the viability of the JEG-3 cells (39 %) for the high concentration of components (1.6 mM ZrO2 and 0.4 mM CA).",
journal = "Chemico-Biological Interactions",
title = "Surface-modified ZrO2 nanoparticles with caffeic acid: Characterization and in vitro evaluation of biosafety for placental cells",
volume = "347",
pages = "109618",
doi = "10.1016/j.cbi.2021.109618"
}

Lazić, V. M., Pirković, A., Sredojević, D., Marković, J. P., Papan, J., Ahrenkiel, S. P., Janković-Častvan, I., Dekanski, D., Jovanović Krivokuća, M.,& Nedeljković, J.. (2021). Surface-modified ZrO2 nanoparticles with caffeic acid: Characterization and in vitro evaluation of biosafety for placental cells. in Chemico-Biological Interactions, 347, 109618.
https://doi.org/10.1016/j.cbi.2021.109618

Lazić VM, Pirković A, Sredojević D, Marković JP, Papan J, Ahrenkiel SP, Janković-Častvan I, Dekanski D, Jovanović Krivokuća M, Nedeljković J. Surface-modified ZrO2 nanoparticles with caffeic acid: Characterization and in vitro evaluation of biosafety for placental cells. in Chemico-Biological Interactions. 2021;347:109618.
doi:10.1016/j.cbi.2021.109618 .

Lazić, Vesna M., Pirković, Andrea, Sredojević, Dušan, Marković, Jelena P., Papan, Jelena, Ahrenkiel, S. Phillip, Janković-Častvan, Ivona, Dekanski, Dragana, Jovanović Krivokuća, Milica, Nedeljković, Jovan, "Surface-modified ZrO2 nanoparticles with caffeic acid: Characterization and in vitro evaluation of biosafety for placental cells" in Chemico-Biological Interactions, 347 (2021):109618,
https://doi.org/10.1016/j.cbi.2021.109618 . .