TY  - JOUR
AU  - Čakar, Uroš
AU  - Grozdanić, Nađa
AU  - Pejin, Boris
AU  - Vasić, Vesna M.
AU  - Čakar, Mira M.
AU  - Petrović, Aleksandar V.
AU  - Đorđević, Brižita
PY  - 2018
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/7772
AB  - α-Glucosidase inhibitory activity (AGL) of fruit wine samples made from blueberry, black chokeberry, blackberry, raspberry and sour cherry cultivars grown in Serbia was studied using an microvinification procedure. More precisely, both sugar and enzyme were added to the fruit must before fermentation for half of the samples. This increased the extraction of phenolic compounds. All the samples showed higher bioactivity compared to acarbose, the compound used as a positive control. Blueberry (IC50 ~27 ± 1 µg/ml) and black chokeberry (IC50 ~28 ± 1 µg/ml) wine samples had the highest values regardless of the vinification method. In addition to this, chlorogenic and caffeic acids were recognised as their key AGL bioactives. Taken all together, the fruit wine samples or their lyophilised extracts may be considered as complementary medicine supplements of potential interest for the control of postprandial hyperglycemia.
T2  - Food Bioscience
T1  - Impact of vinification procedure on fruit wine inhibitory activity against α-glucosidase
VL  - 25
SP  - 1
EP  - 7
DO  - 10.1016/j.fbio.2018.06.009
ER  - 

@article{
author = "Čakar, Uroš and Grozdanić, Nađa and Pejin, Boris and Vasić, Vesna M. and Čakar, Mira M. and Petrović, Aleksandar V. and Đorđević, Brižita",
year = "2018",
abstract = "α-Glucosidase inhibitory activity (AGL) of fruit wine samples made from blueberry, black chokeberry, blackberry, raspberry and sour cherry cultivars grown in Serbia was studied using an microvinification procedure. More precisely, both sugar and enzyme were added to the fruit must before fermentation for half of the samples. This increased the extraction of phenolic compounds. All the samples showed higher bioactivity compared to acarbose, the compound used as a positive control. Blueberry (IC50 ~27 ± 1 µg/ml) and black chokeberry (IC50 ~28 ± 1 µg/ml) wine samples had the highest values regardless of the vinification method. In addition to this, chlorogenic and caffeic acids were recognised as their key AGL bioactives. Taken all together, the fruit wine samples or their lyophilised extracts may be considered as complementary medicine supplements of potential interest for the control of postprandial hyperglycemia.",
journal = "Food Bioscience",
title = "Impact of vinification procedure on fruit wine inhibitory activity against α-glucosidase",
volume = "25",
pages = "1-7",
doi = "10.1016/j.fbio.2018.06.009"
}

Čakar, U., Grozdanić, N., Pejin, B., Vasić, V. M., Čakar, M. M., Petrović, A. V.,& Đorđević, B.. (2018). Impact of vinification procedure on fruit wine inhibitory activity against α-glucosidase. in Food Bioscience, 25, 1-7.
https://doi.org/10.1016/j.fbio.2018.06.009

Čakar U, Grozdanić N, Pejin B, Vasić VM, Čakar MM, Petrović AV, Đorđević B. Impact of vinification procedure on fruit wine inhibitory activity against α-glucosidase. in Food Bioscience. 2018;25:1-7.
doi:10.1016/j.fbio.2018.06.009 .

Čakar, Uroš, Grozdanić, Nađa, Pejin, Boris, Vasić, Vesna M., Čakar, Mira M., Petrović, Aleksandar V., Đorđević, Brižita, "Impact of vinification procedure on fruit wine inhibitory activity against α-glucosidase" in Food Bioscience, 25 (2018):1-7,
https://doi.org/10.1016/j.fbio.2018.06.009 . .

TY  - JOUR
AU  - Vasić, Vesna M.
AU  - Živanović, MA
AU  - Čakar, Mira M.
AU  - Savić, Jasmina
AU  - Nedeljković, Jovan
AU  - Bugarcic, ZD
PY  - 2005
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2879
AB  - The reaction mechanism and thermodynamic parameters of the complex formation between [PdCl(dien)](+) and sulfur-containing ligands L-cysteine and glutathione (GSH) were investigated in the presence of sodium dodecyl sulfate micelles in the pH range 0.5-3.5. The reaction rates were determined under pseudo-first-order conditions (ligand in excess) in the temperature range 276-299 K by using the stopped-flow technique. A reaction mechanism was proposed that consisted of at least two parallel paths involving protonated and zwitterionic forms of thiols. The pH effects on reaction rate were interpreted in terms of the electrostatic interactions between the negatively charged micelle surface and different ionic forms of the ligand species. The calculation of pH-dependent activation parameters (Delta H-not equal and Delta S-not equal) revealed the considerable catalytic effects on the rate of complexation. The entropy of activation is strongly negative in the presence and absence of micelles, which is compatible with an associative reaction mechanism. Copyright (c) 2004 John Wiley T Sons, Ltd.
T2  - Journal of Physical Organic Chemistry
T1  - Influence of acidity on the reaction between [PdCl(dien)](+) and L-cysteine or glutathione in the presence of sodium dodecyl sulfate micelles
VL  - 18
IS  - 5
SP  - 441
EP  - 447
DO  - 10.1002/poc.880
ER  - 

@article{
author = "Vasić, Vesna M. and Živanović, MA and Čakar, Mira M. and Savić, Jasmina and Nedeljković, Jovan and Bugarcic, ZD",
year = "2005",
abstract = "The reaction mechanism and thermodynamic parameters of the complex formation between [PdCl(dien)](+) and sulfur-containing ligands L-cysteine and glutathione (GSH) were investigated in the presence of sodium dodecyl sulfate micelles in the pH range 0.5-3.5. The reaction rates were determined under pseudo-first-order conditions (ligand in excess) in the temperature range 276-299 K by using the stopped-flow technique. A reaction mechanism was proposed that consisted of at least two parallel paths involving protonated and zwitterionic forms of thiols. The pH effects on reaction rate were interpreted in terms of the electrostatic interactions between the negatively charged micelle surface and different ionic forms of the ligand species. The calculation of pH-dependent activation parameters (Delta H-not equal and Delta S-not equal) revealed the considerable catalytic effects on the rate of complexation. The entropy of activation is strongly negative in the presence and absence of micelles, which is compatible with an associative reaction mechanism. Copyright (c) 2004 John Wiley T Sons, Ltd.",
journal = "Journal of Physical Organic Chemistry",
title = "Influence of acidity on the reaction between [PdCl(dien)](+) and L-cysteine or glutathione in the presence of sodium dodecyl sulfate micelles",
volume = "18",
number = "5",
pages = "441-447",
doi = "10.1002/poc.880"
}

Vasić, V. M., Živanović, M., Čakar, M. M., Savić, J., Nedeljković, J.,& Bugarcic, Z.. (2005). Influence of acidity on the reaction between [PdCl(dien)](+) and L-cysteine or glutathione in the presence of sodium dodecyl sulfate micelles. in Journal of Physical Organic Chemistry, 18(5), 441-447.
https://doi.org/10.1002/poc.880

Vasić VM, Živanović M, Čakar MM, Savić J, Nedeljković J, Bugarcic Z. Influence of acidity on the reaction between [PdCl(dien)](+) and L-cysteine or glutathione in the presence of sodium dodecyl sulfate micelles. in Journal of Physical Organic Chemistry. 2005;18(5):441-447.
doi:10.1002/poc.880 .

Vasić, Vesna M., Živanović, MA, Čakar, Mira M., Savić, Jasmina, Nedeljković, Jovan, Bugarcic, ZD, "Influence of acidity on the reaction between [PdCl(dien)](+) and L-cysteine or glutathione in the presence of sodium dodecyl sulfate micelles" in Journal of Physical Organic Chemistry, 18, no. 5 (2005):441-447,
https://doi.org/10.1002/poc.880 . .

TY  - CONF
AU  - Živanović, Miloš Z.
AU  - Vasić, Vesna M.
AU  - Čakar, Mira M.
PY  - 2004
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9491
AB  - We examined the micellar effects on the mechanisms of complex formation between [PdCl(dien)]Cl and amino acids L-cysteine and Gluthathione in the pH range from 0.5 to 3.5. In the presence 1×10-2 M sodium dodecyl sulphate micelles (SDS) the strongest effect on the reaction rate around pH 2 was observed.
PB  - Society of Physical Chemists of Serbia
C3  - Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry
T1  - pH dependent kinetics of [PdCl(dien)]+  reaction with some amino acids in the presence of SDS
VL  - 1
SP  - 249
EP  - 251
UR  - https://hdl.handle.net/21.15107/rcub_vinar_9491
ER  - 

@conference{
author = "Živanović, Miloš Z. and Vasić, Vesna M. and Čakar, Mira M.",
year = "2004",
abstract = "We examined the micellar effects on the mechanisms of complex formation between [PdCl(dien)]Cl and amino acids L-cysteine and Gluthathione in the pH range from 0.5 to 3.5. In the presence 1×10-2 M sodium dodecyl sulphate micelles (SDS) the strongest effect on the reaction rate around pH 2 was observed.",
publisher = "Society of Physical Chemists of Serbia",
journal = "Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry",
title = "pH dependent kinetics of [PdCl(dien)]+  reaction with some amino acids in the presence of SDS",
volume = "1",
pages = "249-251",
url = "https://hdl.handle.net/21.15107/rcub_vinar_9491"
}

Živanović, M. Z., Vasić, V. M.,& Čakar, M. M.. (2004). pH dependent kinetics of [PdCl(dien)]+  reaction with some amino acids in the presence of SDS. in Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry
Society of Physical Chemists of Serbia., 1, 249-251.
https://hdl.handle.net/21.15107/rcub_vinar_9491

Živanović MZ, Vasić VM, Čakar MM. pH dependent kinetics of [PdCl(dien)]+  reaction with some amino acids in the presence of SDS. in Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry. 2004;1:249-251.
https://hdl.handle.net/21.15107/rcub_vinar_9491 .

Živanović, Miloš Z., Vasić, Vesna M., Čakar, Mira M., "pH dependent kinetics of [PdCl(dien)]+  reaction with some amino acids in the presence of SDS" in Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry, 1 (2004):249-251,
https://hdl.handle.net/21.15107/rcub_vinar_9491 .

TY  - JOUR
AU  - Vasić, Vesna M.
AU  - Čakar, Mira M.
AU  - Savić, Jasmina
AU  - Petrović, B
AU  - Nedeljković, Jovan
AU  - Bugarcic, I
PY  - 2003
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2601
AB  - The effect of sodium dodecyl sulfate (SDS) micelles on the kinetics of the complex formation between [PdCl(dien)](+) and sulfur containing ligands L-cysteine and glutathione (GSH) was investigated by using the stopped-flow technique under pseudo-first order conditions (ligand in excess) in the acidity range from pH 1 to 6. The presence of anionic micelles induced the acceleration of the complex formation in the entire acidity range with the maxima corresponding to the first protolytic constant of the ligands. This effect was interpreted in terms of the attractive electrostatic interaction between reacting species and the micellar surface and their effective concentration in the vicinity of micelles. An increase of the ionic strength leads to a decrease of the rate of complex formation in the presence of anionic micelles due to competition of reactive species with cations originating from inert salt for the micellar surface. The calculation of activation parameters revealed that the entropy of activation is strongly negative in the presence and in the absence of micelles, which is compatible with an associative reaction mechanism. (C) 2002 Elsevier Science Ltd. All rights reserved.
T2  - Polyhedron
T1  - Influence of sodium dodecyl sulfate on the kinetics of complex formation between [PdCl(dien)](+) and sulfur containing ligands L-cysteine and glutathione
VL  - 22
IS  - 2
SP  - 279
EP  - 285
DO  - 10.1016/S0277-5387(02)01307-4
ER  - 

@article{
author = "Vasić, Vesna M. and Čakar, Mira M. and Savić, Jasmina and Petrović, B and Nedeljković, Jovan and Bugarcic, I",
year = "2003",
abstract = "The effect of sodium dodecyl sulfate (SDS) micelles on the kinetics of the complex formation between [PdCl(dien)](+) and sulfur containing ligands L-cysteine and glutathione (GSH) was investigated by using the stopped-flow technique under pseudo-first order conditions (ligand in excess) in the acidity range from pH 1 to 6. The presence of anionic micelles induced the acceleration of the complex formation in the entire acidity range with the maxima corresponding to the first protolytic constant of the ligands. This effect was interpreted in terms of the attractive electrostatic interaction between reacting species and the micellar surface and their effective concentration in the vicinity of micelles. An increase of the ionic strength leads to a decrease of the rate of complex formation in the presence of anionic micelles due to competition of reactive species with cations originating from inert salt for the micellar surface. The calculation of activation parameters revealed that the entropy of activation is strongly negative in the presence and in the absence of micelles, which is compatible with an associative reaction mechanism. (C) 2002 Elsevier Science Ltd. All rights reserved.",
journal = "Polyhedron",
title = "Influence of sodium dodecyl sulfate on the kinetics of complex formation between [PdCl(dien)](+) and sulfur containing ligands L-cysteine and glutathione",
volume = "22",
number = "2",
pages = "279-285",
doi = "10.1016/S0277-5387(02)01307-4"
}

Vasić, V. M., Čakar, M. M., Savić, J., Petrović, B., Nedeljković, J.,& Bugarcic, I.. (2003). Influence of sodium dodecyl sulfate on the kinetics of complex formation between [PdCl(dien)](+) and sulfur containing ligands L-cysteine and glutathione. in Polyhedron, 22(2), 279-285.
https://doi.org/10.1016/S0277-5387(02)01307-4

Vasić VM, Čakar MM, Savić J, Petrović B, Nedeljković J, Bugarcic I. Influence of sodium dodecyl sulfate on the kinetics of complex formation between [PdCl(dien)](+) and sulfur containing ligands L-cysteine and glutathione. in Polyhedron. 2003;22(2):279-285.
doi:10.1016/S0277-5387(02)01307-4 .

Vasić, Vesna M., Čakar, Mira M., Savić, Jasmina, Petrović, B, Nedeljković, Jovan, Bugarcic, I, "Influence of sodium dodecyl sulfate on the kinetics of complex formation between [PdCl(dien)](+) and sulfur containing ligands L-cysteine and glutathione" in Polyhedron, 22, no. 2 (2003):279-285,
https://doi.org/10.1016/S0277-5387(02)01307-4 . .

TY  - JOUR
AU  - Milovanović, GA
AU  - Čakar, Mira M.
AU  - Vučić, Nevenka B.
AU  - Jokanović, Milan
PY  - 2000
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2397
AB  - In this work it was established that, in the presence of ammonium carbonate, traces of manganese(II) catalyse the oxidation of Nile Blue A by hydrogen peroxide, which enables its: kinetic determination in the concentration range from 6.6 to 65.9 ng cm(-3), the detection limit being 8.0 x 10(-2) ng cm(-3). Antiviral/antitumour substances modify the catalytic activity of manganese (TT): 1-beta -D-ribofuranosyl-1,2,4-triazole-3-carboxamide, ribavirin, increases the catalytic effect of manganese(II), while 2-beta -D-ribofuranosyl-thiazole-4-carboxamide, tiazofurin, acts as an inhibitor. On the basis of these effects, a kinetic method for determining ribavirin concentrations from 0.5 x 10(-1) to 4.0 x 10(-1) mug cm(-3) and tiazofurin concentrations from 0.3 to 2.6 mug cm(-3) is proposed. The kinetics of the indicator reaction were studied ill the presence of the substances examined, the kinetic equations established, and the constants of the corresponding reaction rates calculated. The effect of temperature on these reactions was also investigated. The method was applied to the determination of manganese(II) in mineral water and ribavirin in pharmaceutical preparations.
T2  - Microchimica Acta
T1  - Selective indicator reaction for kinetic determination of traces of manganese(II), ribavirin and tiazofurin
VL  - 135
IS  - 3-4
SP  - 173
EP  - 178
DO  - 10.1007/s006040070007
ER  - 

@article{
author = "Milovanović, GA and Čakar, Mira M. and Vučić, Nevenka B. and Jokanović, Milan",
year = "2000",
abstract = "In this work it was established that, in the presence of ammonium carbonate, traces of manganese(II) catalyse the oxidation of Nile Blue A by hydrogen peroxide, which enables its: kinetic determination in the concentration range from 6.6 to 65.9 ng cm(-3), the detection limit being 8.0 x 10(-2) ng cm(-3). Antiviral/antitumour substances modify the catalytic activity of manganese (TT): 1-beta -D-ribofuranosyl-1,2,4-triazole-3-carboxamide, ribavirin, increases the catalytic effect of manganese(II), while 2-beta -D-ribofuranosyl-thiazole-4-carboxamide, tiazofurin, acts as an inhibitor. On the basis of these effects, a kinetic method for determining ribavirin concentrations from 0.5 x 10(-1) to 4.0 x 10(-1) mug cm(-3) and tiazofurin concentrations from 0.3 to 2.6 mug cm(-3) is proposed. The kinetics of the indicator reaction were studied ill the presence of the substances examined, the kinetic equations established, and the constants of the corresponding reaction rates calculated. The effect of temperature on these reactions was also investigated. The method was applied to the determination of manganese(II) in mineral water and ribavirin in pharmaceutical preparations.",
journal = "Microchimica Acta",
title = "Selective indicator reaction for kinetic determination of traces of manganese(II), ribavirin and tiazofurin",
volume = "135",
number = "3-4",
pages = "173-178",
doi = "10.1007/s006040070007"
}

Milovanović, G., Čakar, M. M., Vučić, N. B.,& Jokanović, M.. (2000). Selective indicator reaction for kinetic determination of traces of manganese(II), ribavirin and tiazofurin. in Microchimica Acta, 135(3-4), 173-178.
https://doi.org/10.1007/s006040070007

Milovanović G, Čakar MM, Vučić NB, Jokanović M. Selective indicator reaction for kinetic determination of traces of manganese(II), ribavirin and tiazofurin. in Microchimica Acta. 2000;135(3-4):173-178.
doi:10.1007/s006040070007 .

Milovanović, GA, Čakar, Mira M., Vučić, Nevenka B., Jokanović, Milan, "Selective indicator reaction for kinetic determination of traces of manganese(II), ribavirin and tiazofurin" in Microchimica Acta, 135, no. 3-4 (2000):173-178,
https://doi.org/10.1007/s006040070007 . .

TY  - JOUR
AU  - Vasić, Vesna M.
AU  - Premović, S
AU  - Čakar, Mira M.
AU  - Radak, Bojan
AU  - Milovanović, G
PY  - 2000
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/6289
AB  - The equilibria of the complex formation between AuCl4-n(OH)(n)(-) and I- was studied spectrophotometrically in aqueous solutions containing KI:Au(III)less than or equal to 2 in the acidity range from 1 M HCl to pH 7 at 25 degrees C, From the hydrogen ion and Cl- ion dependence of the absorption spectra, it was found that AuCl(2)l(2)(-) and Au(OH)(2)I-2(-) complexes were formed. The equilibrium constants of complex formation were determined.
T2  - Journal of the Serbian Chemical Society
T1  - Spectrophotometric investigations of the reaction between gold(III) and potassium iodide
VL  - 65
IS  - 5-6
SP  - 345
EP  - 352
UR  - https://hdl.handle.net/21.15107/rcub_vinar_6289
ER  - 

@article{
author = "Vasić, Vesna M. and Premović, S and Čakar, Mira M. and Radak, Bojan and Milovanović, G",
year = "2000",
abstract = "The equilibria of the complex formation between AuCl4-n(OH)(n)(-) and I- was studied spectrophotometrically in aqueous solutions containing KI:Au(III)less than or equal to 2 in the acidity range from 1 M HCl to pH 7 at 25 degrees C, From the hydrogen ion and Cl- ion dependence of the absorption spectra, it was found that AuCl(2)l(2)(-) and Au(OH)(2)I-2(-) complexes were formed. The equilibrium constants of complex formation were determined.",
journal = "Journal of the Serbian Chemical Society",
title = "Spectrophotometric investigations of the reaction between gold(III) and potassium iodide",
volume = "65",
number = "5-6",
pages = "345-352",
url = "https://hdl.handle.net/21.15107/rcub_vinar_6289"
}

Vasić, V. M., Premović, S., Čakar, M. M., Radak, B.,& Milovanović, G.. (2000). Spectrophotometric investigations of the reaction between gold(III) and potassium iodide. in Journal of the Serbian Chemical Society, 65(5-6), 345-352.
https://hdl.handle.net/21.15107/rcub_vinar_6289

Vasić VM, Premović S, Čakar MM, Radak B, Milovanović G. Spectrophotometric investigations of the reaction between gold(III) and potassium iodide. in Journal of the Serbian Chemical Society. 2000;65(5-6):345-352.
https://hdl.handle.net/21.15107/rcub_vinar_6289 .

Vasić, Vesna M., Premović, S, Čakar, Mira M., Radak, Bojan, Milovanović, G, "Spectrophotometric investigations of the reaction between gold(III) and potassium iodide" in Journal of the Serbian Chemical Society, 65, no. 5-6 (2000):345-352,
https://hdl.handle.net/21.15107/rcub_vinar_6289 .

TY  - JOUR
AU  - Joksić, Gordana
AU  - Stankovic, M
AU  - Vasić, Vesna M.
AU  - Čakar, Mira M.
AU  - Jokanović, Milan
PY  - 2000
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2383
AB  - Cytotoxic effects of the antiviremic drug ribavirin (1-beta -D-ribofuranosyl-1,2,4-triazole-3-carboxamide) were evaluated in vitro measuring micronucleus formation and cell proliferation kinetics in whole blood cultures employing cytokinesis block (CB) micronucleus test. The cells were exposed to ribavirin doses ranging from 0.05-0.65 mu mol/ml at three different incubation times. The frequency of micronuclei in treated samples demonstrated relatively low ability of ribavirin to induce micronuclei. However, the lowest concentration of ribavirin markedly changed the frequency of mononucleated and multinucleated cells, particularly binucleated ones, which declined significantly. The decline in the frequency of binucleate cells was followed with accumulation of greater number of mononucleate cells. Decreased proliferation potential of lymphocytes treated with ribavirin indicates that cells are arrested prior to metaphase. The present investigation showed that ribavirin is capable to induce a delay in cellular proliferation at all the doses assayed. The study demonstrated that CB micronucleus assay is simple and rapid method that can be used to assess toxic effect of drugs in vitro.
T2  - Neoplasma
T1  - Influence of ribavirin on the micronucleus formation and in vitro proliferation of human lymphocytes
VL  - 47
IS  - 5
SP  - 283
EP  - 287
UR  - https://hdl.handle.net/21.15107/rcub_vinar_2383
ER  - 

@article{
author = "Joksić, Gordana and Stankovic, M and Vasić, Vesna M. and Čakar, Mira M. and Jokanović, Milan",
year = "2000",
abstract = "Cytotoxic effects of the antiviremic drug ribavirin (1-beta -D-ribofuranosyl-1,2,4-triazole-3-carboxamide) were evaluated in vitro measuring micronucleus formation and cell proliferation kinetics in whole blood cultures employing cytokinesis block (CB) micronucleus test. The cells were exposed to ribavirin doses ranging from 0.05-0.65 mu mol/ml at three different incubation times. The frequency of micronuclei in treated samples demonstrated relatively low ability of ribavirin to induce micronuclei. However, the lowest concentration of ribavirin markedly changed the frequency of mononucleated and multinucleated cells, particularly binucleated ones, which declined significantly. The decline in the frequency of binucleate cells was followed with accumulation of greater number of mononucleate cells. Decreased proliferation potential of lymphocytes treated with ribavirin indicates that cells are arrested prior to metaphase. The present investigation showed that ribavirin is capable to induce a delay in cellular proliferation at all the doses assayed. The study demonstrated that CB micronucleus assay is simple and rapid method that can be used to assess toxic effect of drugs in vitro.",
journal = "Neoplasma",
title = "Influence of ribavirin on the micronucleus formation and in vitro proliferation of human lymphocytes",
volume = "47",
number = "5",
pages = "283-287",
url = "https://hdl.handle.net/21.15107/rcub_vinar_2383"
}

Joksić, G., Stankovic, M., Vasić, V. M., Čakar, M. M.,& Jokanović, M.. (2000). Influence of ribavirin on the micronucleus formation and in vitro proliferation of human lymphocytes. in Neoplasma, 47(5), 283-287.
https://hdl.handle.net/21.15107/rcub_vinar_2383

Joksić G, Stankovic M, Vasić VM, Čakar MM, Jokanović M. Influence of ribavirin on the micronucleus formation and in vitro proliferation of human lymphocytes. in Neoplasma. 2000;47(5):283-287.
https://hdl.handle.net/21.15107/rcub_vinar_2383 .

Joksić, Gordana, Stankovic, M, Vasić, Vesna M., Čakar, Mira M., Jokanović, Milan, "Influence of ribavirin on the micronucleus formation and in vitro proliferation of human lymphocytes" in Neoplasma, 47, no. 5 (2000):283-287,
https://hdl.handle.net/21.15107/rcub_vinar_2383 .

TY  - JOUR
AU  - Čakar, Mira M.
AU  - Vasić, Vesna M.
AU  - Petkovska, Ljubica T.
AU  - Stojić, Dragica Lj.
AU  - Avramov-Ivic, M
AU  - Milovanović, GA
PY  - 1999
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2258
AB  - Newly synthesized oximes, mono and bis imidazole derivatives, which promise to be more effective acetylcholinesterase reactivators than standard antidotes used, were investigated by spectrophotometric and electrochemical methods. The electrochemical investigations confirmed the existence of overlapping equilibria, obtained by spectrophotometric methods. Dissociation constants of those oximes were also obtained by numerical treatment of overlapping equilibria, using the Lavendberg-Marquardt least square method, and when compared with the same for some similar compounds, were found to be very effective acetylcholinesterase reactivators. The distribution of ionic forms of the investigated oximes, as a dependence of pH values, was calculated from the obtained values of dissociation constants. The results indicated that many oxime anions will be available at physiological pH 7.4 and a relative increased ability to reactivate inhibited acetylcholinesterase could be expected. (C) 1999 Elsevier Science B.V. All rights reserved.
T2  - Journal of Pharmaceutical and Biomedical Analysis
T1  - Spectrophotometric and electrochemical study of protolytic equilibria of some oximes-acetylcholinesterase reactivators
VL  - 20
IS  - 4
SP  - 655
EP  - 662
DO  - 10.1016/S0731-7085(99)00056-4
ER  - 

@article{
author = "Čakar, Mira M. and Vasić, Vesna M. and Petkovska, Ljubica T. and Stojić, Dragica Lj. and Avramov-Ivic, M and Milovanović, GA",
year = "1999",
abstract = "Newly synthesized oximes, mono and bis imidazole derivatives, which promise to be more effective acetylcholinesterase reactivators than standard antidotes used, were investigated by spectrophotometric and electrochemical methods. The electrochemical investigations confirmed the existence of overlapping equilibria, obtained by spectrophotometric methods. Dissociation constants of those oximes were also obtained by numerical treatment of overlapping equilibria, using the Lavendberg-Marquardt least square method, and when compared with the same for some similar compounds, were found to be very effective acetylcholinesterase reactivators. The distribution of ionic forms of the investigated oximes, as a dependence of pH values, was calculated from the obtained values of dissociation constants. The results indicated that many oxime anions will be available at physiological pH 7.4 and a relative increased ability to reactivate inhibited acetylcholinesterase could be expected. (C) 1999 Elsevier Science B.V. All rights reserved.",
journal = "Journal of Pharmaceutical and Biomedical Analysis",
title = "Spectrophotometric and electrochemical study of protolytic equilibria of some oximes-acetylcholinesterase reactivators",
volume = "20",
number = "4",
pages = "655-662",
doi = "10.1016/S0731-7085(99)00056-4"
}

Čakar, M. M., Vasić, V. M., Petkovska, L. T., Stojić, D. Lj., Avramov-Ivic, M.,& Milovanović, G.. (1999). Spectrophotometric and electrochemical study of protolytic equilibria of some oximes-acetylcholinesterase reactivators. in Journal of Pharmaceutical and Biomedical Analysis, 20(4), 655-662.
https://doi.org/10.1016/S0731-7085(99)00056-4

Čakar MM, Vasić VM, Petkovska LT, Stojić DL, Avramov-Ivic M, Milovanović G. Spectrophotometric and electrochemical study of protolytic equilibria of some oximes-acetylcholinesterase reactivators. in Journal of Pharmaceutical and Biomedical Analysis. 1999;20(4):655-662.
doi:10.1016/S0731-7085(99)00056-4 .

Čakar, Mira M., Vasić, Vesna M., Petkovska, Ljubica T., Stojić, Dragica Lj., Avramov-Ivic, M, Milovanović, GA, "Spectrophotometric and electrochemical study of protolytic equilibria of some oximes-acetylcholinesterase reactivators" in Journal of Pharmaceutical and Biomedical Analysis, 20, no. 4 (1999):655-662,
https://doi.org/10.1016/S0731-7085(99)00056-4 . .

TY  - JOUR
AU  - Janković, Ivana A.
AU  - Čakar, Mira M.
AU  - Nedeljković, Jovan
PY  - 1999
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2256
AB  - The influence of the anionic surfactant sodium dodecyl sulfate on the rate of the reaction between the cationic form of Nile Blue A and hydrogen peroxide was investigated in the pH range from 5 to 8.5. A retardation of the oxidation of Nile Blue A with hydrogen peroxide of three orders of magnitude was observed at pH 8.5 in the presence of anionic micelles compared to the kinetic data in water. The retardation effect was less pronounced at lower pH values. These effects were explained by the electrostatic interaction of the species involved in the reaction with the negatively charged micellar surface and their effective separation in the vicinity of the micellar surface.
T2  - Journal of the Serbian Chemical Society
T1  - Influence of sodium dodecyl sulfate on the reaction between Nile Blue A and hydrogen peroxide
VL  - 64
IS  - 5-6
SP  - 359
EP  - 364
UR  - https://hdl.handle.net/21.15107/rcub_vinar_2256
ER  - 

@article{
author = "Janković, Ivana A. and Čakar, Mira M. and Nedeljković, Jovan",
year = "1999",
abstract = "The influence of the anionic surfactant sodium dodecyl sulfate on the rate of the reaction between the cationic form of Nile Blue A and hydrogen peroxide was investigated in the pH range from 5 to 8.5. A retardation of the oxidation of Nile Blue A with hydrogen peroxide of three orders of magnitude was observed at pH 8.5 in the presence of anionic micelles compared to the kinetic data in water. The retardation effect was less pronounced at lower pH values. These effects were explained by the electrostatic interaction of the species involved in the reaction with the negatively charged micellar surface and their effective separation in the vicinity of the micellar surface.",
journal = "Journal of the Serbian Chemical Society",
title = "Influence of sodium dodecyl sulfate on the reaction between Nile Blue A and hydrogen peroxide",
volume = "64",
number = "5-6",
pages = "359-364",
url = "https://hdl.handle.net/21.15107/rcub_vinar_2256"
}

Janković, I. A., Čakar, M. M.,& Nedeljković, J.. (1999). Influence of sodium dodecyl sulfate on the reaction between Nile Blue A and hydrogen peroxide. in Journal of the Serbian Chemical Society, 64(5-6), 359-364.
https://hdl.handle.net/21.15107/rcub_vinar_2256

Janković IA, Čakar MM, Nedeljković J. Influence of sodium dodecyl sulfate on the reaction between Nile Blue A and hydrogen peroxide. in Journal of the Serbian Chemical Society. 1999;64(5-6):359-364.
https://hdl.handle.net/21.15107/rcub_vinar_2256 .

Janković, Ivana A., Čakar, Mira M., Nedeljković, Jovan, "Influence of sodium dodecyl sulfate on the reaction between Nile Blue A and hydrogen peroxide" in Journal of the Serbian Chemical Society, 64, no. 5-6 (1999):359-364,
https://hdl.handle.net/21.15107/rcub_vinar_2256 .