TY  - JOUR
AU  - Ražić, Slavica
AU  - Arsenijević, Jelena
AU  - Đogo Mračević, Svetlana
AU  - Mušović, Jasmina
AU  - Trtić-Petrović, Tatjana
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/11222
AB  - More environment-friendly solvents in analytical chemistry are almost inevitable in both sample preparation and analysis to meet the high standards of sustainable chemistry and human welfare. In this review paper, a critical look at the advantages and still unsolved problems of most potential classes of green solvents is presented to give an overview of the current state-of-the-art in this field. Replacing volatile organic compounds (VOCs) by ecofriendly and benign solvents in extractions/separations in sample preparation, as the most tedious and demanding step in analysis, is one of roads toward sustainable chemistry. Water under sub- and supercritical conditions, carbon-dioxide, ionic liquids (ILs), deep eutectic solvents (DESs), and those of natural origin (NADES) belong to the most promising classes of solvents in green analytical chemistry. Basic theory and mechanisms of their use illustrated by representative but not exhaustive list of examples related to complex matrices (environmental and natural food products) from analytical practice are presented in this review. Perspectives of QuEChERS, in line with GAC principles, are highlighted, in line with current trends of “going green” for quick, easy, cheap, effective, rugged, and safe analytical methods. Compliance with green chemistry (GC), especially green analytical chemistry (GAC) principles, is not a fashionable issue but, more the trend toward a sustainable future with greener chemistry; thus, green metrics are an unavoidable tool to measure how green the applied method or procedure is. Herein, the most common tools will be presented and discussed, such as national environmental method index (NEMI), analytical ecoscale, green analytical procedure index (GAPI), analytical greenness calculator (AGREE), complementary green analytical procedure index (ComplexGAPI), and analytical greenness metric for sample preparation (AGREEprep). The future trends for research and development in this still expanding field are presented in a critical view of advantages and disadvantages as well as improvement of the validation of analytical procedures. The creation of new certified reference materials (CRMs) and validated methods for specified analytes in complex matrices is a demanding task in the coming years. Tailor-made solvents with physicochemical properties for intended use are required for the selective extraction and separation and open numerous possibilities and huge potential for future research and industrial applications.
T2  - Analyst
T1  - Greener chemistry in analytical sciences: from green solvents to applications in complex matrices. Current challenges and future perspectives: a critical review
VL  - 148
IS  - 14
SP  - 3130
EP  - 3152
DO  - 10.1039/D3AN00498H
ER  - 

@article{
author = "Ražić, Slavica and Arsenijević, Jelena and Đogo Mračević, Svetlana and Mušović, Jasmina and Trtić-Petrović, Tatjana",
year = "2023",
abstract = "More environment-friendly solvents in analytical chemistry are almost inevitable in both sample preparation and analysis to meet the high standards of sustainable chemistry and human welfare. In this review paper, a critical look at the advantages and still unsolved problems of most potential classes of green solvents is presented to give an overview of the current state-of-the-art in this field. Replacing volatile organic compounds (VOCs) by ecofriendly and benign solvents in extractions/separations in sample preparation, as the most tedious and demanding step in analysis, is one of roads toward sustainable chemistry. Water under sub- and supercritical conditions, carbon-dioxide, ionic liquids (ILs), deep eutectic solvents (DESs), and those of natural origin (NADES) belong to the most promising classes of solvents in green analytical chemistry. Basic theory and mechanisms of their use illustrated by representative but not exhaustive list of examples related to complex matrices (environmental and natural food products) from analytical practice are presented in this review. Perspectives of QuEChERS, in line with GAC principles, are highlighted, in line with current trends of “going green” for quick, easy, cheap, effective, rugged, and safe analytical methods. Compliance with green chemistry (GC), especially green analytical chemistry (GAC) principles, is not a fashionable issue but, more the trend toward a sustainable future with greener chemistry; thus, green metrics are an unavoidable tool to measure how green the applied method or procedure is. Herein, the most common tools will be presented and discussed, such as national environmental method index (NEMI), analytical ecoscale, green analytical procedure index (GAPI), analytical greenness calculator (AGREE), complementary green analytical procedure index (ComplexGAPI), and analytical greenness metric for sample preparation (AGREEprep). The future trends for research and development in this still expanding field are presented in a critical view of advantages and disadvantages as well as improvement of the validation of analytical procedures. The creation of new certified reference materials (CRMs) and validated methods for specified analytes in complex matrices is a demanding task in the coming years. Tailor-made solvents with physicochemical properties for intended use are required for the selective extraction and separation and open numerous possibilities and huge potential for future research and industrial applications.",
journal = "Analyst",
title = "Greener chemistry in analytical sciences: from green solvents to applications in complex matrices. Current challenges and future perspectives: a critical review",
volume = "148",
number = "14",
pages = "3130-3152",
doi = "10.1039/D3AN00498H"
}

Ražić, S., Arsenijević, J., Đogo Mračević, S., Mušović, J.,& Trtić-Petrović, T.. (2023). Greener chemistry in analytical sciences: from green solvents to applications in complex matrices. Current challenges and future perspectives: a critical review. in Analyst, 148(14), 3130-3152.
https://doi.org/10.1039/D3AN00498H

Ražić S, Arsenijević J, Đogo Mračević S, Mušović J, Trtić-Petrović T. Greener chemistry in analytical sciences: from green solvents to applications in complex matrices. Current challenges and future perspectives: a critical review. in Analyst. 2023;148(14):3130-3152.
doi:10.1039/D3AN00498H .

Ražić, Slavica, Arsenijević, Jelena, Đogo Mračević, Svetlana, Mušović, Jasmina, Trtić-Petrović, Tatjana, "Greener chemistry in analytical sciences: from green solvents to applications in complex matrices. Current challenges and future perspectives: a critical review" in Analyst, 148, no. 14 (2023):3130-3152,
https://doi.org/10.1039/D3AN00498H . .

TY  - JOUR
AU  - Arsenijević, Jelena
AU  - Marković, Jelena P.
AU  - Sostaric, Ivan
AU  - Ražić, Slavica
PY  - 2013
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/5723
AB  - The volatile fraction of the leaves of Thymus pannonicus All. (Lamiaceae) was analyzed by headspace extraction followed by GC-FID and GC-MS analysis. The different headspace profiles were recognized, with citral and with monoterpene hydrocarbons as dominant compounds. In addition, the determination of Cr, Co, Ni, Mo, Cu, Zn, Mn, Fe, Mg, Ca, K and Na was conducted by spectroscopic techniques (FAAS, GFAAS and ICP-OES). In order to evaluate the relationship between volatile organic compounds and metals, a chemometrics approach was applied. The data obtained by analysis of the headspace and elemental content were subjected to correlation analysis, factor analysis, principal component analysis and cluster analysis. A number of significant correlations of metals with plant volatiles were found. Correlation of Zn with citral, Mn with oxygenated monoterpenes and Mg with beta-bourbonene, could be explained by involvement of metals in the biosynthesis of volatile organic compounds. (C) 2013 Elsevier Masson SAS. All rights reserved.
T2  - Plant Physiology and Biochemistry
T1  - A chemometrics as a powerful tool in the elucidation of the role of metals in the biosynthesis of volatile organic compounds in Hungarian thyme samples
VL  - 71
SP  - 298
EP  - 306
DO  - 10.1016/j.plaphy.2013.08.002
ER  - 

@article{
author = "Arsenijević, Jelena and Marković, Jelena P. and Sostaric, Ivan and Ražić, Slavica",
year = "2013",
abstract = "The volatile fraction of the leaves of Thymus pannonicus All. (Lamiaceae) was analyzed by headspace extraction followed by GC-FID and GC-MS analysis. The different headspace profiles were recognized, with citral and with monoterpene hydrocarbons as dominant compounds. In addition, the determination of Cr, Co, Ni, Mo, Cu, Zn, Mn, Fe, Mg, Ca, K and Na was conducted by spectroscopic techniques (FAAS, GFAAS and ICP-OES). In order to evaluate the relationship between volatile organic compounds and metals, a chemometrics approach was applied. The data obtained by analysis of the headspace and elemental content were subjected to correlation analysis, factor analysis, principal component analysis and cluster analysis. A number of significant correlations of metals with plant volatiles were found. Correlation of Zn with citral, Mn with oxygenated monoterpenes and Mg with beta-bourbonene, could be explained by involvement of metals in the biosynthesis of volatile organic compounds. (C) 2013 Elsevier Masson SAS. All rights reserved.",
journal = "Plant Physiology and Biochemistry",
title = "A chemometrics as a powerful tool in the elucidation of the role of metals in the biosynthesis of volatile organic compounds in Hungarian thyme samples",
volume = "71",
pages = "298-306",
doi = "10.1016/j.plaphy.2013.08.002"
}

Arsenijević, J., Marković, J. P., Sostaric, I.,& Ražić, S.. (2013). A chemometrics as a powerful tool in the elucidation of the role of metals in the biosynthesis of volatile organic compounds in Hungarian thyme samples. in Plant Physiology and Biochemistry, 71, 298-306.
https://doi.org/10.1016/j.plaphy.2013.08.002

Arsenijević J, Marković JP, Sostaric I, Ražić S. A chemometrics as a powerful tool in the elucidation of the role of metals in the biosynthesis of volatile organic compounds in Hungarian thyme samples. in Plant Physiology and Biochemistry. 2013;71:298-306.
doi:10.1016/j.plaphy.2013.08.002 .

Arsenijević, Jelena, Marković, Jelena P., Sostaric, Ivan, Ražić, Slavica, "A chemometrics as a powerful tool in the elucidation of the role of metals in the biosynthesis of volatile organic compounds in Hungarian thyme samples" in Plant Physiology and Biochemistry, 71 (2013):298-306,
https://doi.org/10.1016/j.plaphy.2013.08.002 . .