TY  - JOUR
AU  - Dimitrijević, Teodora
AU  - Novaković, Irena T.
AU  - Radanović, Dušanka D.
AU  - Novaković, Slađana B.
AU  - Rodić, Marko V.
AU  - Anđelković, Katarina
AU  - Šumar-Ristović, Maja
PY  - 2020
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8908
AB  - In this article, synthesis, spectral and X-ray structure characterization, antimicrobial activity and Brine shrimp test of two new Cu(II) complexes with a salicylaldehyde derivative have been reported. Complexes [Cu(L)(bipy)]BF4·0.5H2O and [Cu2(L)2(phen)2](BF4)2 were obtained in the reaction of Cu(BF4)2·6H2O, deprotonated 4-(diethylamino)−2-hydroxybenzaldehyde ligand (L) and α-diimine (2,2’-bipyridine or 1,10-phenanthroline). The complex with bipyridine is mononuclear, containing one L and one bipyridine ligand in a distorted square-planar cation with a BF4 − anion and lattice water molecule, whereas the complex with phenanthroline is a dinuclear centrosymmetric dimeric cation, containing two L ligands along with two phenanthroline ligands and BF4 − anions. The coordination geometry of each Cu(II) ion can be described as an elongated square pyramid. MS-ESI spectroscopy indicated that [Cu2(L)2(phen)2](BF4)2 is mononuclear in DMSO solution. In vitro antibacterial and antifungal activity was tested against four Gram-positive, four Gram-negative bacteria and three fungal strains. Complexes showed significantly stronger antibacterial activities than parent ligands. The mononuclear phenanthroline complex in solution showed very good antimicrobial activity, which is comparable to the activity of the standard antibiotic amikacin against all tested bacterial strains. The same complex has better antifungal activity than fluconazole, which was used as a standard. Results of the brine shrimp test indicate that both complexes have good toxicity against Artemia nauplii.
T2  - Journal of Coordination Chemistry
T1  - Synthesis, spectral and structural characterization and biological activity of Cu(II) complexes with 4-(diethylamino)salicylaldehyde and α-diimines
VL  - 73
IS  - 4
SP  - 702
EP  - 716
DO  - 10.1080/00958972.2020.1740212
ER  - 

@article{
author = "Dimitrijević, Teodora and Novaković, Irena T. and Radanović, Dušanka D. and Novaković, Slađana B. and Rodić, Marko V. and Anđelković, Katarina and Šumar-Ristović, Maja",
year = "2020",
abstract = "In this article, synthesis, spectral and X-ray structure characterization, antimicrobial activity and Brine shrimp test of two new Cu(II) complexes with a salicylaldehyde derivative have been reported. Complexes [Cu(L)(bipy)]BF4·0.5H2O and [Cu2(L)2(phen)2](BF4)2 were obtained in the reaction of Cu(BF4)2·6H2O, deprotonated 4-(diethylamino)−2-hydroxybenzaldehyde ligand (L) and α-diimine (2,2’-bipyridine or 1,10-phenanthroline). The complex with bipyridine is mononuclear, containing one L and one bipyridine ligand in a distorted square-planar cation with a BF4 − anion and lattice water molecule, whereas the complex with phenanthroline is a dinuclear centrosymmetric dimeric cation, containing two L ligands along with two phenanthroline ligands and BF4 − anions. The coordination geometry of each Cu(II) ion can be described as an elongated square pyramid. MS-ESI spectroscopy indicated that [Cu2(L)2(phen)2](BF4)2 is mononuclear in DMSO solution. In vitro antibacterial and antifungal activity was tested against four Gram-positive, four Gram-negative bacteria and three fungal strains. Complexes showed significantly stronger antibacterial activities than parent ligands. The mononuclear phenanthroline complex in solution showed very good antimicrobial activity, which is comparable to the activity of the standard antibiotic amikacin against all tested bacterial strains. The same complex has better antifungal activity than fluconazole, which was used as a standard. Results of the brine shrimp test indicate that both complexes have good toxicity against Artemia nauplii.",
journal = "Journal of Coordination Chemistry",
title = "Synthesis, spectral and structural characterization and biological activity of Cu(II) complexes with 4-(diethylamino)salicylaldehyde and α-diimines",
volume = "73",
number = "4",
pages = "702-716",
doi = "10.1080/00958972.2020.1740212"
}

Dimitrijević, T., Novaković, I. T., Radanović, D. D., Novaković, S. B., Rodić, M. V., Anđelković, K.,& Šumar-Ristović, M.. (2020). Synthesis, spectral and structural characterization and biological activity of Cu(II) complexes with 4-(diethylamino)salicylaldehyde and α-diimines. in Journal of Coordination Chemistry, 73(4), 702-716.
https://doi.org/10.1080/00958972.2020.1740212

Dimitrijević T, Novaković IT, Radanović DD, Novaković SB, Rodić MV, Anđelković K, Šumar-Ristović M. Synthesis, spectral and structural characterization and biological activity of Cu(II) complexes with 4-(diethylamino)salicylaldehyde and α-diimines. in Journal of Coordination Chemistry. 2020;73(4):702-716.
doi:10.1080/00958972.2020.1740212 .

Dimitrijević, Teodora, Novaković, Irena T., Radanović, Dušanka D., Novaković, Slađana B., Rodić, Marko V., Anđelković, Katarina, Šumar-Ristović, Maja, "Synthesis, spectral and structural characterization and biological activity of Cu(II) complexes with 4-(diethylamino)salicylaldehyde and α-diimines" in Journal of Coordination Chemistry, 73, no. 4 (2020):702-716,
https://doi.org/10.1080/00958972.2020.1740212 . .