TY  - JOUR
AU  - Gavrilović, Ljubica
AU  - Stojiljković, Vesna
AU  - Stanić, Vojislav
AU  - Jovanović, Dragoljub
AU  - Pejić, Snežana
AU  - Borović, Branka
AU  - Pajović, Snežana B.
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12395
AB  - inden honey represents a unique honey variety valued for its nutritional benefits, distinctive taste and aroma. Phenols, polyphenols, flavonoids, ascorbic acid and phenolic acids in honey have antioxidant activities. This study aimed to investigate the effects of linden honey on the activities of antioxidant enzymes catalase (CAT) and glutathione peroxidase (GPx), as well as on the concentration of malondialdehyde (MDA) in individually housed animals. The investigated parameters were quantified using spectrophotometric method for determination of enzyme activities and MDA concentration in the blood. We found that treatment with linden honey in the socially isolated animals significantly increased the enzyme activities of CAT and GPx, and significantly decreased the concentration of MDA. The modulation of CAT and GPx activities in socially isolated animals treated with linden honey may be very important for understanding the role of honey in the capacity of antioxidant defense system to increase and maintain its stability in psychosocial stress conditions. Our results may be important in biomedical research for understanding the role of honey in the amelioration of oxidative stress.
AB  - Lipov med predstavlja jedinstvenu vrstu meda cenjenu zbog svoje nutritivne prednosti, specifičnog ukusa i mirisa. Fenoli, polifenoli, fl avonoidi, askorbinska kiselina i fenolne kiseline u medu imaju antioksidativno dejstvo. Ovo istraživanje je imalo za cilj da ispita uticaj lipovog meda na aktivnosti antioksidativnih enzima katalaze (CAT) i glutation peroksidaze (GPx), kao i na koncentraciju malondialdehida (MDA) kod individualno smeštenih životinja. Ispitivani parametri su kvantifi kovani spektrofotometrijskim metodama. Ustanovili smo da tretman lipovim medom, kod socijalno izolovanih životinja, značajno povećava aktivnost enzima CAT i GPx, ali da značajno smanjuje koncentraciju MDA. Modulacija aktivnosti CAT i GPx u krvi socijalno izolovanih životinja tretiranih lipovim medom, može biti veoma važna za razumevanje uloge meda u sposobnosti antioksidativnog odbrambenog sistema da poveća i održi njegovu stabilnost u uslovima psihosocijalnog stresa. Naši rezultati mogu biti važni u biomedicinskim istraživanjima za razumevanje uloge meda u smanjenju oksidativnog stresa.
T2  - Acta Veterinaria
T1  - Antioxidant Status in the Blood of Psychosocially Stressed Rats Treated with Honey
T1  - Antioksidativni status u krvi pacova izlaganih psihosocijalnom stresu tretiranih medom
VL  - 73
IS  - 4
SP  - 464
EP  - 472
DO  - 10.2478/acve-2023-0035
ER  - 

@article{
author = "Gavrilović, Ljubica and Stojiljković, Vesna and Stanić, Vojislav and Jovanović, Dragoljub and Pejić, Snežana and Borović, Branka and Pajović, Snežana B.",
year = "2023",
abstract = "inden honey represents a unique honey variety valued for its nutritional benefits, distinctive taste and aroma. Phenols, polyphenols, flavonoids, ascorbic acid and phenolic acids in honey have antioxidant activities. This study aimed to investigate the effects of linden honey on the activities of antioxidant enzymes catalase (CAT) and glutathione peroxidase (GPx), as well as on the concentration of malondialdehyde (MDA) in individually housed animals. The investigated parameters were quantified using spectrophotometric method for determination of enzyme activities and MDA concentration in the blood. We found that treatment with linden honey in the socially isolated animals significantly increased the enzyme activities of CAT and GPx, and significantly decreased the concentration of MDA. The modulation of CAT and GPx activities in socially isolated animals treated with linden honey may be very important for understanding the role of honey in the capacity of antioxidant defense system to increase and maintain its stability in psychosocial stress conditions. Our results may be important in biomedical research for understanding the role of honey in the amelioration of oxidative stress., Lipov med predstavlja jedinstvenu vrstu meda cenjenu zbog svoje nutritivne prednosti, specifičnog ukusa i mirisa. Fenoli, polifenoli, fl avonoidi, askorbinska kiselina i fenolne kiseline u medu imaju antioksidativno dejstvo. Ovo istraživanje je imalo za cilj da ispita uticaj lipovog meda na aktivnosti antioksidativnih enzima katalaze (CAT) i glutation peroksidaze (GPx), kao i na koncentraciju malondialdehida (MDA) kod individualno smeštenih životinja. Ispitivani parametri su kvantifi kovani spektrofotometrijskim metodama. Ustanovili smo da tretman lipovim medom, kod socijalno izolovanih životinja, značajno povećava aktivnost enzima CAT i GPx, ali da značajno smanjuje koncentraciju MDA. Modulacija aktivnosti CAT i GPx u krvi socijalno izolovanih životinja tretiranih lipovim medom, može biti veoma važna za razumevanje uloge meda u sposobnosti antioksidativnog odbrambenog sistema da poveća i održi njegovu stabilnost u uslovima psihosocijalnog stresa. Naši rezultati mogu biti važni u biomedicinskim istraživanjima za razumevanje uloge meda u smanjenju oksidativnog stresa.",
journal = "Acta Veterinaria",
title = "Antioxidant Status in the Blood of Psychosocially Stressed Rats Treated with Honey, Antioksidativni status u krvi pacova izlaganih psihosocijalnom stresu tretiranih medom",
volume = "73",
number = "4",
pages = "464-472",
doi = "10.2478/acve-2023-0035"
}

Gavrilović, L., Stojiljković, V., Stanić, V., Jovanović, D., Pejić, S., Borović, B.,& Pajović, S. B.. (2023). Antioxidant Status in the Blood of Psychosocially Stressed Rats Treated with Honey. in Acta Veterinaria, 73(4), 464-472.
https://doi.org/10.2478/acve-2023-0035

Gavrilović L, Stojiljković V, Stanić V, Jovanović D, Pejić S, Borović B, Pajović SB. Antioxidant Status in the Blood of Psychosocially Stressed Rats Treated with Honey. in Acta Veterinaria. 2023;73(4):464-472.
doi:10.2478/acve-2023-0035 .

Gavrilović, Ljubica, Stojiljković, Vesna, Stanić, Vojislav, Jovanović, Dragoljub, Pejić, Snežana, Borović, Branka, Pajović, Snežana B., "Antioxidant Status in the Blood of Psychosocially Stressed Rats Treated with Honey" in Acta Veterinaria, 73, no. 4 (2023):464-472,
https://doi.org/10.2478/acve-2023-0035 . .