Šećerov, Bojana Lj.

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  • Šećerov, Bojana Lj. (18)
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Author's Bibliography

Quality control in radiation processing in the Vinča Institute Radiation Plant: Case study

Šećerov, Bojana; Stančov, Danijela; Radenković, Mirjana; Dramićanin, Miroslav

(2016)

TY  - JOUR
AU  - Šećerov, Bojana
AU  - Stančov, Danijela
AU  - Radenković, Mirjana
AU  - Dramićanin, Miroslav
PY  - 2016
UR  - http://casopisi.junis.ni.ac.rs/index.php/FUPhysChemTech/article/view/1535
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/7627
AB  - The irradiation process control has to define facility parameters, validation of product and routine control of the irradiation process during exploitation. To meet the regulations, it is necessary to stop the exploitation and do the qualification exercises after changes in the source loading, source geometry or product transport system. In order to save time, the new combined approach has been analyzed for qualification of sterilization process used in the Vinča Institute Radiation Plant. The absorbed dose is calculated assuming that the irradiation process runs with specified parameters. The results of absorbed dose measurements in an experiment done during the sterilization process were used for dose calculations. The calculated absorbed doses are compared with measured ones. The criterion for a positive qualification is the superposition of calculated and measured values. Two different types of dosimeters are used for measurements: ethanol-chlorobenzene and alanine. The measurement traceability is achieved through the calibration by the Riso National Laboratory, Denmark. In this case study, the determined dwell time for target dose is 450s. 1.23 is dose uniformity ratio in the box with plastic products with dose minimum at the bottom corners in the center and dose maximum at the top of the surface plane of the box parallel to the source. The calculated and measured absorbed doses show the same difference of 13% between the surface and the central plane in the box. The dose reproducibility for irradiation process is 3.5%.
AB  - Kontrola procesa ozračivanja mora da definiše parametre postrojenja, validaciju proizvoda i rutinsku kontrolu procesa tokom eksploatacije. Da bi se ispunili zahteve propisa, neophodno je prekinuti eksploataciju i uraditi kvalifikaciju procesa ozračivanja posle svake dopune izvora, promene geometrije izvora ili transportnog sistema. U cilju uštede vremena, analiziran je novi kombinovani pristup kvalifikacije procesa sterilizacije u Radijacionoj jedinici Instituta 'Vinča'. Apsorbovana doza je izračunavana pretpostavljajući da proces teče po zadatim parametrima. Za izračunavanje koriste se rezultati merenja apsorbovane doze u eksperimentu koji je izveden u toku procesa sterilizacije. Izračunate apsorbovane doze upoređuju se sa izmerenim. Kriterijum za pozitivnu kvalifikaciju procesa je slaganje izračunatih i izmerenih vrednosti. Za merenja su korišćena dva tipa dozimetara: etanol-hlorbenzen i alanin. Merna sledljivost je postignuta preko kalibracije u RISO nacionalnoj laboratoriji u Danskoj. U ovoj studiji, određena je dužina koraka za ciljanu dozu od 450s. 1,23 je odnos homogenosti doze u kutiji sa plastičnim proizvodima, sa minimumom doze u donjim uglovima centralne ravni i maksimalnom dozom na vrhu ivice kutije u ravni paralelnoj sa izvorom. Izračunate i izmerene apsorbovane doze pokazuju istu razliku od 13% između površinske i centralne ravni kutije. Reproduktivnost doze za proces ozračivanja je 3,5%.
T2  - Facta Universitatis, Series: Physics, Chemistry and Technology
T1  - Quality control in radiation processing in the Vinča Institute Radiation Plant: Case study
T1  - Kontrola kvaliteta u tehnologiji obrade zračenjem - studija slučaja Radijacione jedinice u Institutu 'Vinča'
VL  - 14
IS  - 2
SP  - 105
EP  - 113
DO  - 10.2298/FUPCT1602105S
ER  - 
@article{
author = "Šećerov, Bojana and Stančov, Danijela and Radenković, Mirjana and Dramićanin, Miroslav",
year = "2016",
abstract = "The irradiation process control has to define facility parameters, validation of product and routine control of the irradiation process during exploitation. To meet the regulations, it is necessary to stop the exploitation and do the qualification exercises after changes in the source loading, source geometry or product transport system. In order to save time, the new combined approach has been analyzed for qualification of sterilization process used in the Vinča Institute Radiation Plant. The absorbed dose is calculated assuming that the irradiation process runs with specified parameters. The results of absorbed dose measurements in an experiment done during the sterilization process were used for dose calculations. The calculated absorbed doses are compared with measured ones. The criterion for a positive qualification is the superposition of calculated and measured values. Two different types of dosimeters are used for measurements: ethanol-chlorobenzene and alanine. The measurement traceability is achieved through the calibration by the Riso National Laboratory, Denmark. In this case study, the determined dwell time for target dose is 450s. 1.23 is dose uniformity ratio in the box with plastic products with dose minimum at the bottom corners in the center and dose maximum at the top of the surface plane of the box parallel to the source. The calculated and measured absorbed doses show the same difference of 13% between the surface and the central plane in the box. The dose reproducibility for irradiation process is 3.5%., Kontrola procesa ozračivanja mora da definiše parametre postrojenja, validaciju proizvoda i rutinsku kontrolu procesa tokom eksploatacije. Da bi se ispunili zahteve propisa, neophodno je prekinuti eksploataciju i uraditi kvalifikaciju procesa ozračivanja posle svake dopune izvora, promene geometrije izvora ili transportnog sistema. U cilju uštede vremena, analiziran je novi kombinovani pristup kvalifikacije procesa sterilizacije u Radijacionoj jedinici Instituta 'Vinča'. Apsorbovana doza je izračunavana pretpostavljajući da proces teče po zadatim parametrima. Za izračunavanje koriste se rezultati merenja apsorbovane doze u eksperimentu koji je izveden u toku procesa sterilizacije. Izračunate apsorbovane doze upoređuju se sa izmerenim. Kriterijum za pozitivnu kvalifikaciju procesa je slaganje izračunatih i izmerenih vrednosti. Za merenja su korišćena dva tipa dozimetara: etanol-hlorbenzen i alanin. Merna sledljivost je postignuta preko kalibracije u RISO nacionalnoj laboratoriji u Danskoj. U ovoj studiji, određena je dužina koraka za ciljanu dozu od 450s. 1,23 je odnos homogenosti doze u kutiji sa plastičnim proizvodima, sa minimumom doze u donjim uglovima centralne ravni i maksimalnom dozom na vrhu ivice kutije u ravni paralelnoj sa izvorom. Izračunate i izmerene apsorbovane doze pokazuju istu razliku od 13% između površinske i centralne ravni kutije. Reproduktivnost doze za proces ozračivanja je 3,5%.",
journal = "Facta Universitatis, Series: Physics, Chemistry and Technology",
title = "Quality control in radiation processing in the Vinča Institute Radiation Plant: Case study, Kontrola kvaliteta u tehnologiji obrade zračenjem - studija slučaja Radijacione jedinice u Institutu 'Vinča'",
volume = "14",
number = "2",
pages = "105-113",
doi = "10.2298/FUPCT1602105S"
}
Šećerov, B., Stančov, D., Radenković, M.,& Dramićanin, M.. (2016). Quality control in radiation processing in the Vinča Institute Radiation Plant: Case study. in Facta Universitatis, Series: Physics, Chemistry and Technology, 14(2), 105-113.
https://doi.org/10.2298/FUPCT1602105S
Šećerov B, Stančov D, Radenković M, Dramićanin M. Quality control in radiation processing in the Vinča Institute Radiation Plant: Case study. in Facta Universitatis, Series: Physics, Chemistry and Technology. 2016;14(2):105-113.
doi:10.2298/FUPCT1602105S .
Šećerov, Bojana, Stančov, Danijela, Radenković, Mirjana, Dramićanin, Miroslav, "Quality control in radiation processing in the Vinča Institute Radiation Plant: Case study" in Facta Universitatis, Series: Physics, Chemistry and Technology, 14, no. 2 (2016):105-113,
https://doi.org/10.2298/FUPCT1602105S . .

The potential of in vivo EPR in evaluating free radical reactions in irradiated rats and mechanisms of radioprotection

Jovanović, M.; Šećerov, Bojana; Bačić, Goran

(Society of Physical Chemists of Serbia, 2016)

TY  - CONF
AU  - Jovanović, M.
AU  - Šećerov, Bojana
AU  - Bačić, Goran
PY  - 2016
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9212
AB  - We  investigated  the  potential  of in  vivoelectron  paramagnetic  resonance (EPR)  in  assessingchemical  reactions  that  occur  during  ionizing  irradiation and  capabilities  of  two  radioprotectors  (an  antibiotic,  anisomycin  and  a naturally  occurring  tiol,  Gl2011)  to  enhance  survival  during  irradiation. Radioprotectors selected are supposed to have different modes of action and in vivoEPR was used to assess whether free radical scavenging has arole in their  action  as  radioprotectors.  Both  compounds  exhibited  similar  and highly   efficient   radioprotective   capabilities   according   to   the   30-days survival  test  (96%  and  87%,  respectively  after  the  dose  of  6.7  Gy). In  vivoEPR showed that free radical scavenging has an important role in the action of  GL2011,  but  not  in  the  case  of  anisomycin.  In  conclusion,  EPR  have unique  capabilities  in  studying  free  radicals in  vivoand  can  beuseful addition to battery of methods needed to study radioprotectorsin vivo.
PB  - Society of Physical Chemists of Serbia
C3  - Physical chemistry 2016 : 13th international conference on fundamental and applied aspects of physical chemistry
T1  - The potential of in vivo EPR in evaluating free radical reactions in irradiated rats and mechanisms of radioprotection
SP  - 491
EP  - 494
UR  - https://hdl.handle.net/21.15107/rcub_vinar_9212
ER  - 
@conference{
author = "Jovanović, M. and Šećerov, Bojana and Bačić, Goran",
year = "2016",
abstract = "We  investigated  the  potential  of in  vivoelectron  paramagnetic  resonance (EPR)  in  assessingchemical  reactions  that  occur  during  ionizing  irradiation and  capabilities  of  two  radioprotectors  (an  antibiotic,  anisomycin  and  a naturally  occurring  tiol,  Gl2011)  to  enhance  survival  during  irradiation. Radioprotectors selected are supposed to have different modes of action and in vivoEPR was used to assess whether free radical scavenging has arole in their  action  as  radioprotectors.  Both  compounds  exhibited  similar  and highly   efficient   radioprotective   capabilities   according   to   the   30-days survival  test  (96%  and  87%,  respectively  after  the  dose  of  6.7  Gy). In  vivoEPR showed that free radical scavenging has an important role in the action of  GL2011,  but  not  in  the  case  of  anisomycin.  In  conclusion,  EPR  have unique  capabilities  in  studying  free  radicals in  vivoand  can  beuseful addition to battery of methods needed to study radioprotectorsin vivo.",
publisher = "Society of Physical Chemists of Serbia",
journal = "Physical chemistry 2016 : 13th international conference on fundamental and applied aspects of physical chemistry",
title = "The potential of in vivo EPR in evaluating free radical reactions in irradiated rats and mechanisms of radioprotection",
pages = "491-494",
url = "https://hdl.handle.net/21.15107/rcub_vinar_9212"
}
Jovanović, M., Šećerov, B.,& Bačić, G.. (2016). The potential of in vivo EPR in evaluating free radical reactions in irradiated rats and mechanisms of radioprotection. in Physical chemistry 2016 : 13th international conference on fundamental and applied aspects of physical chemistry
Society of Physical Chemists of Serbia., 491-494.
https://hdl.handle.net/21.15107/rcub_vinar_9212
Jovanović M, Šećerov B, Bačić G. The potential of in vivo EPR in evaluating free radical reactions in irradiated rats and mechanisms of radioprotection. in Physical chemistry 2016 : 13th international conference on fundamental and applied aspects of physical chemistry. 2016;:491-494.
https://hdl.handle.net/21.15107/rcub_vinar_9212 .
Jovanović, M., Šećerov, Bojana, Bačić, Goran, "The potential of in vivo EPR in evaluating free radical reactions in irradiated rats and mechanisms of radioprotection" in Physical chemistry 2016 : 13th international conference on fundamental and applied aspects of physical chemistry (2016):491-494,
https://hdl.handle.net/21.15107/rcub_vinar_9212 .

Uncertainty and routine use of Aerial L-alanine - Electron spin resonance dosimetry system

Šećerov, Bojana Lj.; Radenković, Mirjana; Dramićanin, Miroslav

(Elsevier, 2016)

TY  - JOUR
AU  - Šećerov, Bojana Lj.
AU  - Radenković, Mirjana
AU  - Dramićanin, Miroslav
PY  - 2016
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/1098
AB  - Aerial L-alanine pellet dosimeter is characterized by MiniScope MS300 electron spin resonance spectrometer measurements using AerEDE Version 2.0.4. software for dose calculation. The measurement traceability is achieved by Aerial dosimetry laboratory where dosimeters for calibration curve were irradiated by electron beam accelerator. Dose determinations in Aerial are traceable to National Physical Laboratory (NPL). The software used for construction of calibration curve gives also the standard deviation of the residuals of measurements for calibration that is used for dose uncertainty calculation. In aim to determine whether this value can actually be taken as absorbed dose uncertainty during usage of this dosimetry system, alanine dosimeters were irradiated with doses between 5 and 32 kGy by Co-60 laboratory source for internal calibration. The dose rate at the places for irradiation was (20 +/- 0.5) mGy s(-1) determined by Fricke dosimeter. Measurement of each irradiated dosimeter was repeated ten times in ten days. The results of measurements were analyzed to identify the sources of uncertainty, as well as their quantification in evaluation of total measurement uncertainty. In addition to statistical effects, the very low dose rate that was used for the irradiation of alanine dosimeters affects the measurements of absorbed dose, particularly for higher absorbed doses where the measured dose can be up to 3% lower than the real. (C) 2016 Elsevier Ltd. All rights reserved.
PB  - Elsevier
T2  - Radiation Measurements
T1  - Uncertainty and routine use of Aerial L-alanine - Electron spin resonance dosimetry system
VL  - 89
SP  - 63
EP  - 67
DO  - 10.1016/j.radmeas.2016.03.003
ER  - 
@article{
author = "Šećerov, Bojana Lj. and Radenković, Mirjana and Dramićanin, Miroslav",
year = "2016",
abstract = "Aerial L-alanine pellet dosimeter is characterized by MiniScope MS300 electron spin resonance spectrometer measurements using AerEDE Version 2.0.4. software for dose calculation. The measurement traceability is achieved by Aerial dosimetry laboratory where dosimeters for calibration curve were irradiated by electron beam accelerator. Dose determinations in Aerial are traceable to National Physical Laboratory (NPL). The software used for construction of calibration curve gives also the standard deviation of the residuals of measurements for calibration that is used for dose uncertainty calculation. In aim to determine whether this value can actually be taken as absorbed dose uncertainty during usage of this dosimetry system, alanine dosimeters were irradiated with doses between 5 and 32 kGy by Co-60 laboratory source for internal calibration. The dose rate at the places for irradiation was (20 +/- 0.5) mGy s(-1) determined by Fricke dosimeter. Measurement of each irradiated dosimeter was repeated ten times in ten days. The results of measurements were analyzed to identify the sources of uncertainty, as well as their quantification in evaluation of total measurement uncertainty. In addition to statistical effects, the very low dose rate that was used for the irradiation of alanine dosimeters affects the measurements of absorbed dose, particularly for higher absorbed doses where the measured dose can be up to 3% lower than the real. (C) 2016 Elsevier Ltd. All rights reserved.",
publisher = "Elsevier",
journal = "Radiation Measurements",
title = "Uncertainty and routine use of Aerial L-alanine - Electron spin resonance dosimetry system",
volume = "89",
pages = "63-67",
doi = "10.1016/j.radmeas.2016.03.003"
}
Šećerov, B. Lj., Radenković, M.,& Dramićanin, M.. (2016). Uncertainty and routine use of Aerial L-alanine - Electron spin resonance dosimetry system. in Radiation Measurements
Elsevier., 89, 63-67.
https://doi.org/10.1016/j.radmeas.2016.03.003
Šećerov BL, Radenković M, Dramićanin M. Uncertainty and routine use of Aerial L-alanine - Electron spin resonance dosimetry system. in Radiation Measurements. 2016;89:63-67.
doi:10.1016/j.radmeas.2016.03.003 .
Šećerov, Bojana Lj., Radenković, Mirjana, Dramićanin, Miroslav, "Uncertainty and routine use of Aerial L-alanine - Electron spin resonance dosimetry system" in Radiation Measurements, 89 (2016):63-67,
https://doi.org/10.1016/j.radmeas.2016.03.003 . .
3
2
2

Estimation of Absorbed Dose During Process Interruption in Radiation Processing

Šećerov, Bojana Lj.; Dramićanin, Miroslav

(2015)

TY  - CONF
AU  - Šećerov, Bojana Lj.
AU  - Dramićanin, Miroslav
PY  - 2015
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/7122
AB  - The quality control system enables the standardization of product quality. Dosimetry has an important role in the quality control of radiation processing. The area of radiation processing which is governed most strictly by regulations is radiation sterilization. This process is used as the example to describe the new method for establishing the effect of process interruption on absorbed dose in the Co-60 irradiation plant at the Vinca Institute of Nuclear Sciences. Establishing the effect of process interruption is one of requirements in international regulations, but there are no recommendations for its implementation. A new method has been worked out by graphical extrapolation. The advantage of this method is the ability to carry it out during the sterilization process. The ethanol-chlorobenzene (ECB) dosimeter is used to select the suitable place where absorbed dose is expected to be the most influenced by source transit, i.e. the most close to the source. In the same time, it should be convenient and reproducible for placing dosimeters. Alanine dosimeters were irradiated on this place in time intervals: 2 min., 4 min., 6 min., 8 min., 10 min. Measurements of time starts when the button to lift source is pressed and stops by pressing the button for process interruption (to sink source down). The absorbed doses were measured by ESR spectrometer. The function of absorbed dose versus irradiation time is linear as expected. The extrapolation back to zero time gives the maximal absorbed dose that can be delivered to product during source transit. In our experiment this absorbed dose obtained by this method is 154 Gy.
C3  - RAD Conference Proceedings
T1  - Estimation of Absorbed Dose During Process Interruption in Radiation Processing
SP  - 181
EP  - 184
UR  - https://hdl.handle.net/21.15107/rcub_vinar_7122
ER  - 
@conference{
author = "Šećerov, Bojana Lj. and Dramićanin, Miroslav",
year = "2015",
abstract = "The quality control system enables the standardization of product quality. Dosimetry has an important role in the quality control of radiation processing. The area of radiation processing which is governed most strictly by regulations is radiation sterilization. This process is used as the example to describe the new method for establishing the effect of process interruption on absorbed dose in the Co-60 irradiation plant at the Vinca Institute of Nuclear Sciences. Establishing the effect of process interruption is one of requirements in international regulations, but there are no recommendations for its implementation. A new method has been worked out by graphical extrapolation. The advantage of this method is the ability to carry it out during the sterilization process. The ethanol-chlorobenzene (ECB) dosimeter is used to select the suitable place where absorbed dose is expected to be the most influenced by source transit, i.e. the most close to the source. In the same time, it should be convenient and reproducible for placing dosimeters. Alanine dosimeters were irradiated on this place in time intervals: 2 min., 4 min., 6 min., 8 min., 10 min. Measurements of time starts when the button to lift source is pressed and stops by pressing the button for process interruption (to sink source down). The absorbed doses were measured by ESR spectrometer. The function of absorbed dose versus irradiation time is linear as expected. The extrapolation back to zero time gives the maximal absorbed dose that can be delivered to product during source transit. In our experiment this absorbed dose obtained by this method is 154 Gy.",
journal = "RAD Conference Proceedings",
title = "Estimation of Absorbed Dose During Process Interruption in Radiation Processing",
pages = "181-184",
url = "https://hdl.handle.net/21.15107/rcub_vinar_7122"
}
Šećerov, B. Lj.,& Dramićanin, M.. (2015). Estimation of Absorbed Dose During Process Interruption in Radiation Processing. in RAD Conference Proceedings, 181-184.
https://hdl.handle.net/21.15107/rcub_vinar_7122
Šećerov BL, Dramićanin M. Estimation of Absorbed Dose During Process Interruption in Radiation Processing. in RAD Conference Proceedings. 2015;:181-184.
https://hdl.handle.net/21.15107/rcub_vinar_7122 .
Šećerov, Bojana Lj., Dramićanin, Miroslav, "Estimation of Absorbed Dose During Process Interruption in Radiation Processing" in RAD Conference Proceedings (2015):181-184,
https://hdl.handle.net/21.15107/rcub_vinar_7122 .

Erratum to: Radiation protection from whole-body gamma irradiation (6.7 Gy): behavioural effects and brain protein-level changes by an aminothiol compound GL2011 in the Wistar rat (vol 46, pg 1681, 2014)

Ganesan, Minu Karthika; Jovanović, Miloš; Šećerov, Bojana Lj.; Ignjatović, Marija; Bilban, Martin; Anđus, Pavle R.; El Refaei, Amal; Jung, Gangsoo; Li, Lin; Sase, Ajinkya; Chen, Weiqiang; Bačić, Goran; Lubec, Gert

(2014)

TY  - JOUR
AU  - Ganesan, Minu Karthika
AU  - Jovanović, Miloš
AU  - Šećerov, Bojana Lj.
AU  - Ignjatović, Marija
AU  - Bilban, Martin
AU  - Anđus, Pavle R.
AU  - El Refaei, Amal
AU  - Jung, Gangsoo
AU  - Li, Lin
AU  - Sase, Ajinkya
AU  - Chen, Weiqiang
AU  - Bačić, Goran
AU  - Lubec, Gert
PY  - 2014
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/133
T2  - Amino Acids
T1  - Erratum to: Radiation protection from whole-body gamma irradiation (6.7 Gy): behavioural effects and brain protein-level changes by an aminothiol compound GL2011 in the Wistar rat (vol 46, pg 1681, 2014)
VL  - 46
IS  - 10
SP  - 2445
EP  - 2445
DO  - 10.1007/s00726-014-1791-2
ER  - 
@article{
author = "Ganesan, Minu Karthika and Jovanović, Miloš and Šećerov, Bojana Lj. and Ignjatović, Marija and Bilban, Martin and Anđus, Pavle R. and El Refaei, Amal and Jung, Gangsoo and Li, Lin and Sase, Ajinkya and Chen, Weiqiang and Bačić, Goran and Lubec, Gert",
year = "2014",
journal = "Amino Acids",
title = "Erratum to: Radiation protection from whole-body gamma irradiation (6.7 Gy): behavioural effects and brain protein-level changes by an aminothiol compound GL2011 in the Wistar rat (vol 46, pg 1681, 2014)",
volume = "46",
number = "10",
pages = "2445-2445",
doi = "10.1007/s00726-014-1791-2"
}
Ganesan, M. K., Jovanović, M., Šećerov, B. Lj., Ignjatović, M., Bilban, M., Anđus, P. R., El Refaei, A., Jung, G., Li, L., Sase, A., Chen, W., Bačić, G.,& Lubec, G.. (2014). Erratum to: Radiation protection from whole-body gamma irradiation (6.7 Gy): behavioural effects and brain protein-level changes by an aminothiol compound GL2011 in the Wistar rat (vol 46, pg 1681, 2014). in Amino Acids, 46(10), 2445-2445.
https://doi.org/10.1007/s00726-014-1791-2
Ganesan MK, Jovanović M, Šećerov BL, Ignjatović M, Bilban M, Anđus PR, El Refaei A, Jung G, Li L, Sase A, Chen W, Bačić G, Lubec G. Erratum to: Radiation protection from whole-body gamma irradiation (6.7 Gy): behavioural effects and brain protein-level changes by an aminothiol compound GL2011 in the Wistar rat (vol 46, pg 1681, 2014). in Amino Acids. 2014;46(10):2445-2445.
doi:10.1007/s00726-014-1791-2 .
Ganesan, Minu Karthika, Jovanović, Miloš, Šećerov, Bojana Lj., Ignjatović, Marija, Bilban, Martin, Anđus, Pavle R., El Refaei, Amal, Jung, Gangsoo, Li, Lin, Sase, Ajinkya, Chen, Weiqiang, Bačić, Goran, Lubec, Gert, "Erratum to: Radiation protection from whole-body gamma irradiation (6.7 Gy): behavioural effects and brain protein-level changes by an aminothiol compound GL2011 in the Wistar rat (vol 46, pg 1681, 2014)" in Amino Acids, 46, no. 10 (2014):2445-2445,
https://doi.org/10.1007/s00726-014-1791-2 . .

Increased survival after irradiation followed by regeneration of bone marrow stromal cells with a novel thiol-based radioprotector

Okić-Đorđević, Ivana; Trivanović, Drenka; Jovanović, Miloš; Ignjatović, Marija; Šećerov, Bojana Lj.; Mojovic, Milos; Bugarski, Diana; Bačić, Goran; Anđus, Pavle R.

(2014)

TY  - JOUR
AU  - Okić-Đorđević, Ivana
AU  - Trivanović, Drenka
AU  - Jovanović, Miloš
AU  - Ignjatović, Marija
AU  - Šećerov, Bojana Lj.
AU  - Mojovic, Milos
AU  - Bugarski, Diana
AU  - Bačić, Goran
AU  - Anđus, Pavle R.
PY  - 2014
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/5935
AB  - Aim To investigate the survival of laboratory rats after irradiation and to study the cellularity of their bone marrow and the multipotential mesenchymal stem cells (BM-MSCs) in groups treated with or without a new thiol-based radioprotector (GM2011) Methods Animals were irradiated by a Cobalt gamma source at 6.7 Gy. Treated animals were given i.p. GM2011 30 minutes before and 3 and 7 hours after irradiation. Controls consisted of sham irradiated animals without treatment and animals treated without irradiation. After 30 days post-irradiation, animals were sacrificed and bone marrow cells were prepared from isolated femurs. A colony forming unit-fibroblast (CFU-F) assay was performed to obtain the number of BM-MSCs. Results In the treated group, 87% of animals survived, compared to only 30% in the non-treated irradiated group. Irradiation induced significant changes in the bone marrow of the treated rats (total bone marrow cellularity was reduced by similar to 60% - from 63 to 28 cells x10(6)/femur and the frequency of the CFU-F per femur by similar to 70% - from 357 to 97), however GL2011 almost completely prevented the suppressive effect observed on day 30 post-irradiation (71 cells x 10(6)/femur and 230 CFU-F/femur). Conclusion Although the irradiation dosage was relatively high, GL2011 acted as a very effective new radioprotector. The recovery of the BN-MSCs and their counts support the effectiveness of the studied radioprotector.
T2  - Croatian Medical Journal
T1  - Increased survival after irradiation followed by regeneration of bone marrow stromal cells with a novel thiol-based radioprotector
VL  - 55
IS  - 1
SP  - 45
EP  - 49
DO  - 10.3325/cmj.2014.55.45
ER  - 
@article{
author = "Okić-Đorđević, Ivana and Trivanović, Drenka and Jovanović, Miloš and Ignjatović, Marija and Šećerov, Bojana Lj. and Mojovic, Milos and Bugarski, Diana and Bačić, Goran and Anđus, Pavle R.",
year = "2014",
abstract = "Aim To investigate the survival of laboratory rats after irradiation and to study the cellularity of their bone marrow and the multipotential mesenchymal stem cells (BM-MSCs) in groups treated with or without a new thiol-based radioprotector (GM2011) Methods Animals were irradiated by a Cobalt gamma source at 6.7 Gy. Treated animals were given i.p. GM2011 30 minutes before and 3 and 7 hours after irradiation. Controls consisted of sham irradiated animals without treatment and animals treated without irradiation. After 30 days post-irradiation, animals were sacrificed and bone marrow cells were prepared from isolated femurs. A colony forming unit-fibroblast (CFU-F) assay was performed to obtain the number of BM-MSCs. Results In the treated group, 87% of animals survived, compared to only 30% in the non-treated irradiated group. Irradiation induced significant changes in the bone marrow of the treated rats (total bone marrow cellularity was reduced by similar to 60% - from 63 to 28 cells x10(6)/femur and the frequency of the CFU-F per femur by similar to 70% - from 357 to 97), however GL2011 almost completely prevented the suppressive effect observed on day 30 post-irradiation (71 cells x 10(6)/femur and 230 CFU-F/femur). Conclusion Although the irradiation dosage was relatively high, GL2011 acted as a very effective new radioprotector. The recovery of the BN-MSCs and their counts support the effectiveness of the studied radioprotector.",
journal = "Croatian Medical Journal",
title = "Increased survival after irradiation followed by regeneration of bone marrow stromal cells with a novel thiol-based radioprotector",
volume = "55",
number = "1",
pages = "45-49",
doi = "10.3325/cmj.2014.55.45"
}
Okić-Đorđević, I., Trivanović, D., Jovanović, M., Ignjatović, M., Šećerov, B. Lj., Mojovic, M., Bugarski, D., Bačić, G.,& Anđus, P. R.. (2014). Increased survival after irradiation followed by regeneration of bone marrow stromal cells with a novel thiol-based radioprotector. in Croatian Medical Journal, 55(1), 45-49.
https://doi.org/10.3325/cmj.2014.55.45
Okić-Đorđević I, Trivanović D, Jovanović M, Ignjatović M, Šećerov BL, Mojovic M, Bugarski D, Bačić G, Anđus PR. Increased survival after irradiation followed by regeneration of bone marrow stromal cells with a novel thiol-based radioprotector. in Croatian Medical Journal. 2014;55(1):45-49.
doi:10.3325/cmj.2014.55.45 .
Okić-Đorđević, Ivana, Trivanović, Drenka, Jovanović, Miloš, Ignjatović, Marija, Šećerov, Bojana Lj., Mojovic, Milos, Bugarski, Diana, Bačić, Goran, Anđus, Pavle R., "Increased survival after irradiation followed by regeneration of bone marrow stromal cells with a novel thiol-based radioprotector" in Croatian Medical Journal, 55, no. 1 (2014):45-49,
https://doi.org/10.3325/cmj.2014.55.45 . .
1
1
1

Radiation protection from whole-body gamma irradiation (6.7 Gy): behavioural effects and brain protein-level changes by an aminothiol compound GL2011 in the Wistar rat

Ganesan, Minu Karthika; Jovanović, Miloš; Šećerov, Bojana Lj.; Ignjatović, Marija; Bilban, Martin; Anđus, Pavle R.; El Refaei, Amal; Jung, Gangsoo; Li, Lin; Sase, Ajinkya; Chen, Weiqiang; Bačić, Goran; Lubec, Gert

(2014)

TY  - JOUR
AU  - Ganesan, Minu Karthika
AU  - Jovanović, Miloš
AU  - Šećerov, Bojana Lj.
AU  - Ignjatović, Marija
AU  - Bilban, Martin
AU  - Anđus, Pavle R.
AU  - El Refaei, Amal
AU  - Jung, Gangsoo
AU  - Li, Lin
AU  - Sase, Ajinkya
AU  - Chen, Weiqiang
AU  - Bačić, Goran
AU  - Lubec, Gert
PY  - 2014
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/6052
AB  - GL2011 is a naturally occurring thiol compound and a series of thiol compounds have been proposed as radioprotectors. Radioprotective efficacy of a triple intraperitoneal dose of GL2011 of 100 mg/kg body weight of Wistar rats, 30 min prior to and 3 and 6 h following irradiation (6.7 Gy) was evaluated. Four groups of animals were used, vehicle-treated non-irradiated (VN), GL2011-treated and irradiated (GI), GL2011-treated and non-irradiated (GN) and vehicle-treated and irradiated (VI) (n = 30 per group). The radioprotective efficacy of GL2011 was determined by measuring 28-day survival and intestinal crypt cell survival. Neuroprotection in terms of behaviour was evaluated using the behavioural observational battery, open field test and elevated plus maze paradigm. An RNA microarray was carried out in order to show differences at the RNA level between VI and VN groups. Brain protein changes were identified using a gel-based proteomics method and major brain receptor complex levels were determined by blue-native gels followed by immunoblotting. 28-Day survival rate in VI was 30 %, in GI survival was 93 %, survival of VN and GN was 100 %. Jejunal crypt cell survival was significantly enhanced in GI. Protein-level changes of peroxiredoxin-5, Mn-superoxide dismutase 2, voltage-dependent anion-selective channel protein 1, septin 5 and dopamine D2 receptor complex levels were paralleling radiation damage and protection. Taken together, the findings demonstrate that GL2011 improves survival rates and jejunal crypt survival, provides partial neuroprotection at the behavioural level and modulates proteins known to be involved in protection against oxidative stress-mediated cell damage.
T2  - Amino Acids
T1  - Radiation protection from whole-body gamma irradiation (6.7 Gy): behavioural effects and brain protein-level changes by an aminothiol compound GL2011 in the Wistar rat
VL  - 46
IS  - 7
SP  - 1681
EP  - 1696
DO  - 10.1007/s00726-014-1728-9
ER  - 
@article{
author = "Ganesan, Minu Karthika and Jovanović, Miloš and Šećerov, Bojana Lj. and Ignjatović, Marija and Bilban, Martin and Anđus, Pavle R. and El Refaei, Amal and Jung, Gangsoo and Li, Lin and Sase, Ajinkya and Chen, Weiqiang and Bačić, Goran and Lubec, Gert",
year = "2014",
abstract = "GL2011 is a naturally occurring thiol compound and a series of thiol compounds have been proposed as radioprotectors. Radioprotective efficacy of a triple intraperitoneal dose of GL2011 of 100 mg/kg body weight of Wistar rats, 30 min prior to and 3 and 6 h following irradiation (6.7 Gy) was evaluated. Four groups of animals were used, vehicle-treated non-irradiated (VN), GL2011-treated and irradiated (GI), GL2011-treated and non-irradiated (GN) and vehicle-treated and irradiated (VI) (n = 30 per group). The radioprotective efficacy of GL2011 was determined by measuring 28-day survival and intestinal crypt cell survival. Neuroprotection in terms of behaviour was evaluated using the behavioural observational battery, open field test and elevated plus maze paradigm. An RNA microarray was carried out in order to show differences at the RNA level between VI and VN groups. Brain protein changes were identified using a gel-based proteomics method and major brain receptor complex levels were determined by blue-native gels followed by immunoblotting. 28-Day survival rate in VI was 30 %, in GI survival was 93 %, survival of VN and GN was 100 %. Jejunal crypt cell survival was significantly enhanced in GI. Protein-level changes of peroxiredoxin-5, Mn-superoxide dismutase 2, voltage-dependent anion-selective channel protein 1, septin 5 and dopamine D2 receptor complex levels were paralleling radiation damage and protection. Taken together, the findings demonstrate that GL2011 improves survival rates and jejunal crypt survival, provides partial neuroprotection at the behavioural level and modulates proteins known to be involved in protection against oxidative stress-mediated cell damage.",
journal = "Amino Acids",
title = "Radiation protection from whole-body gamma irradiation (6.7 Gy): behavioural effects and brain protein-level changes by an aminothiol compound GL2011 in the Wistar rat",
volume = "46",
number = "7",
pages = "1681-1696",
doi = "10.1007/s00726-014-1728-9"
}
Ganesan, M. K., Jovanović, M., Šećerov, B. Lj., Ignjatović, M., Bilban, M., Anđus, P. R., El Refaei, A., Jung, G., Li, L., Sase, A., Chen, W., Bačić, G.,& Lubec, G.. (2014). Radiation protection from whole-body gamma irradiation (6.7 Gy): behavioural effects and brain protein-level changes by an aminothiol compound GL2011 in the Wistar rat. in Amino Acids, 46(7), 1681-1696.
https://doi.org/10.1007/s00726-014-1728-9
Ganesan MK, Jovanović M, Šećerov BL, Ignjatović M, Bilban M, Anđus PR, El Refaei A, Jung G, Li L, Sase A, Chen W, Bačić G, Lubec G. Radiation protection from whole-body gamma irradiation (6.7 Gy): behavioural effects and brain protein-level changes by an aminothiol compound GL2011 in the Wistar rat. in Amino Acids. 2014;46(7):1681-1696.
doi:10.1007/s00726-014-1728-9 .
Ganesan, Minu Karthika, Jovanović, Miloš, Šećerov, Bojana Lj., Ignjatović, Marija, Bilban, Martin, Anđus, Pavle R., El Refaei, Amal, Jung, Gangsoo, Li, Lin, Sase, Ajinkya, Chen, Weiqiang, Bačić, Goran, Lubec, Gert, "Radiation protection from whole-body gamma irradiation (6.7 Gy): behavioural effects and brain protein-level changes by an aminothiol compound GL2011 in the Wistar rat" in Amino Acids, 46, no. 7 (2014):1681-1696,
https://doi.org/10.1007/s00726-014-1728-9 . .
6
6
7

Absorbed dose distribution at Vinča radiation plant

Šećerov, Bojana; Stančov, Danijela

(Society of Physical Chemists of Serbia, 2014)

TY  - CONF
AU  - Šećerov, Bojana
AU  - Stančov, Danijela
PY  - 2014
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9198
AB  - The aim of work is to correlate the absorbed dose distribution and gamma
source activity in Vinča Radiation Plant. The measurements of absorbed
doses obtained during the sterilization process of plastic medical products
are compared with similar measurements made during the commissioning of
this plant, but this time by using alanine dosimetry system. The influence of
source activity to depth dose distribution is as expected, but there is no
effect to the height dose distribution. The inhomogeneity of 13% of the dose
across the box was determined is also done by alanine dosimetry system.
PB  - Society of Physical Chemists of Serbia
C3  - Physical chemistry 2014: 12th International Conference on Fundamental and Applied Aspects of Physical Chemistry
T1  - Absorbed dose distribution at Vinča radiation plant
VL  - G-01-P
UR  - https://hdl.handle.net/21.15107/rcub_vinar_9198
ER  - 
@conference{
author = "Šećerov, Bojana and Stančov, Danijela",
year = "2014",
abstract = "The aim of work is to correlate the absorbed dose distribution and gamma
source activity in Vinča Radiation Plant. The measurements of absorbed
doses obtained during the sterilization process of plastic medical products
are compared with similar measurements made during the commissioning of
this plant, but this time by using alanine dosimetry system. The influence of
source activity to depth dose distribution is as expected, but there is no
effect to the height dose distribution. The inhomogeneity of 13% of the dose
across the box was determined is also done by alanine dosimetry system.",
publisher = "Society of Physical Chemists of Serbia",
journal = "Physical chemistry 2014: 12th International Conference on Fundamental and Applied Aspects of Physical Chemistry",
title = "Absorbed dose distribution at Vinča radiation plant",
volume = "G-01-P",
url = "https://hdl.handle.net/21.15107/rcub_vinar_9198"
}
Šećerov, B.,& Stančov, D.. (2014). Absorbed dose distribution at Vinča radiation plant. in Physical chemistry 2014: 12th International Conference on Fundamental and Applied Aspects of Physical Chemistry
Society of Physical Chemists of Serbia., G-01-P.
https://hdl.handle.net/21.15107/rcub_vinar_9198
Šećerov B, Stančov D. Absorbed dose distribution at Vinča radiation plant. in Physical chemistry 2014: 12th International Conference on Fundamental and Applied Aspects of Physical Chemistry. 2014;G-01-P.
https://hdl.handle.net/21.15107/rcub_vinar_9198 .
Šećerov, Bojana, Stančov, Danijela, "Absorbed dose distribution at Vinča radiation plant" in Physical chemistry 2014: 12th International Conference on Fundamental and Applied Aspects of Physical Chemistry, G-01-P (2014),
https://hdl.handle.net/21.15107/rcub_vinar_9198 .

Radiation-Mediated Induction of Apoptotic Cell Death in Rat Hippocampus

Velickovic, Natasa A.; Đorđević, Ana D.; Drakulić, Dunja R.; Šećerov, Bojana Lj.; Grković, Ivana; Milošević, Maja; Horvat, Anica

(2013)

TY  - JOUR
AU  - Velickovic, Natasa A.
AU  - Đorđević, Ana D.
AU  - Drakulić, Dunja R.
AU  - Šećerov, Bojana Lj.
AU  - Grković, Ivana
AU  - Milošević, Maja
AU  - Horvat, Anica
PY  - 2013
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/5594
AB  - Ionizing radiation is commonly used in the treatment of brain tumors but it can impair cognitive functions, such as learning and memory. Since cognitive dysfunctions are predominantly result of cell death by apoptosis in hippocampal cells, in this study we analyzed acute effects of cranial gamma-irradiation (10 Gy) on-expression-of proapoptotic molecules (p53, Box) and antiapoptotic molecule Bcl-2, as well as caspase-3 activation and cytochrome c redistribution in the hippocampus of young rats. The selected regimen of irradiation resembles the established animal model for childhood prophylactic cranial radiotherapy. Our results demonstrated that p53 mRNA expression was unchanged after irradiation, while induction of p53 protein was rapid. In parallel, Bax mRNA and protein levels were also increased following irradiation, whereas Bcl-2 expression was not changed during the examined post-irradiation period. These changes were accompanied with early hallmarks of apoptosis, such as increased cytochrome c release and stimulated activation of caspase-3. Overall, this study demonstrates that cranial irradiation is associated with the augmented apoptotic pathway in the rat hippocampus, which could be related to the cognitive decline observed in patients after prophylactic cranial radiotherapy, but also opens perspective in finding radioprotectors that can mitigate radiation injury of normal brain tissue.
T2  - Nuclear technology and radiation protection
T1  - Radiation-Mediated Induction of Apoptotic Cell Death in Rat Hippocampus
VL  - 28
IS  - 2
SP  - 212
EP  - 220
DO  - 10.2298/NTRP1302212V
ER  - 
@article{
author = "Velickovic, Natasa A. and Đorđević, Ana D. and Drakulić, Dunja R. and Šećerov, Bojana Lj. and Grković, Ivana and Milošević, Maja and Horvat, Anica",
year = "2013",
abstract = "Ionizing radiation is commonly used in the treatment of brain tumors but it can impair cognitive functions, such as learning and memory. Since cognitive dysfunctions are predominantly result of cell death by apoptosis in hippocampal cells, in this study we analyzed acute effects of cranial gamma-irradiation (10 Gy) on-expression-of proapoptotic molecules (p53, Box) and antiapoptotic molecule Bcl-2, as well as caspase-3 activation and cytochrome c redistribution in the hippocampus of young rats. The selected regimen of irradiation resembles the established animal model for childhood prophylactic cranial radiotherapy. Our results demonstrated that p53 mRNA expression was unchanged after irradiation, while induction of p53 protein was rapid. In parallel, Bax mRNA and protein levels were also increased following irradiation, whereas Bcl-2 expression was not changed during the examined post-irradiation period. These changes were accompanied with early hallmarks of apoptosis, such as increased cytochrome c release and stimulated activation of caspase-3. Overall, this study demonstrates that cranial irradiation is associated with the augmented apoptotic pathway in the rat hippocampus, which could be related to the cognitive decline observed in patients after prophylactic cranial radiotherapy, but also opens perspective in finding radioprotectors that can mitigate radiation injury of normal brain tissue.",
journal = "Nuclear technology and radiation protection",
title = "Radiation-Mediated Induction of Apoptotic Cell Death in Rat Hippocampus",
volume = "28",
number = "2",
pages = "212-220",
doi = "10.2298/NTRP1302212V"
}
Velickovic, N. A., Đorđević, A. D., Drakulić, D. R., Šećerov, B. Lj., Grković, I., Milošević, M.,& Horvat, A.. (2013). Radiation-Mediated Induction of Apoptotic Cell Death in Rat Hippocampus. in Nuclear technology and radiation protection, 28(2), 212-220.
https://doi.org/10.2298/NTRP1302212V
Velickovic NA, Đorđević AD, Drakulić DR, Šećerov BL, Grković I, Milošević M, Horvat A. Radiation-Mediated Induction of Apoptotic Cell Death in Rat Hippocampus. in Nuclear technology and radiation protection. 2013;28(2):212-220.
doi:10.2298/NTRP1302212V .
Velickovic, Natasa A., Đorđević, Ana D., Drakulić, Dunja R., Šećerov, Bojana Lj., Grković, Ivana, Milošević, Maja, Horvat, Anica, "Radiation-Mediated Induction of Apoptotic Cell Death in Rat Hippocampus" in Nuclear technology and radiation protection, 28, no. 2 (2013):212-220,
https://doi.org/10.2298/NTRP1302212V . .

A study of gamma-irradiated polyethylenes by temperature modulated differential scanning calorimetry

Galović, Slobodanka; Šećerov, Bojana Lj.; Trifunovic, S.; Miličević, Dejan S.; Suljovrujić, Edin H.

(2012)

TY  - JOUR
AU  - Galović, Slobodanka
AU  - Šećerov, Bojana Lj.
AU  - Trifunovic, S.
AU  - Miličević, Dejan S.
AU  - Suljovrujić, Edin H.
PY  - 2012
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/6967
AB  - Various polyethylenes (PEs) and the effects of high-energy radiation on their structures were widely studied in the past using conventional Differential Scanning Calorimetry (DSC) measurements. In this work, we used the Temperature Modulated Differential Scanning Calorimetry (TMDSC) technique in order to obtain more information about the influence of the initial structural differences and gamma radiation on the evolution in structure and thermal properties of different polyethylenes. For this reason, low density polyethylene (LDPE), linear low density polyethylene (LLDPE) and high density polyethylene (HOPE) samples were exposed to gamma radiation, in air, to a wide range of absorbed doses (up to 2400 kGy). The separation of the total heat flow TMDSC signal into a reversing and non-reversing part enabled us to observe the low-temperature enthalpy relaxation (related to the existence of the rigid amorphous phase) and recrystallisation processes, as well as to follow their radiation-induced evolution and/or that of melting in a more revealing manner compared to the case of the conventional DSC. Consequently, our results indicate that TMDSC could improve the understanding of radiation-induced effects in polymers. (C) 2011 Elsevier Ltd. All rights reserved.
T2  - Radiation Physics and Chemistry
T1  - A study of gamma-irradiated polyethylenes by temperature modulated differential scanning calorimetry
VL  - 81
IS  - 9
SP  - 1374
EP  - 1377
DO  - 10.1016/j.radphyschem.2011.11.054
ER  - 
@article{
author = "Galović, Slobodanka and Šećerov, Bojana Lj. and Trifunovic, S. and Miličević, Dejan S. and Suljovrujić, Edin H.",
year = "2012",
abstract = "Various polyethylenes (PEs) and the effects of high-energy radiation on their structures were widely studied in the past using conventional Differential Scanning Calorimetry (DSC) measurements. In this work, we used the Temperature Modulated Differential Scanning Calorimetry (TMDSC) technique in order to obtain more information about the influence of the initial structural differences and gamma radiation on the evolution in structure and thermal properties of different polyethylenes. For this reason, low density polyethylene (LDPE), linear low density polyethylene (LLDPE) and high density polyethylene (HOPE) samples were exposed to gamma radiation, in air, to a wide range of absorbed doses (up to 2400 kGy). The separation of the total heat flow TMDSC signal into a reversing and non-reversing part enabled us to observe the low-temperature enthalpy relaxation (related to the existence of the rigid amorphous phase) and recrystallisation processes, as well as to follow their radiation-induced evolution and/or that of melting in a more revealing manner compared to the case of the conventional DSC. Consequently, our results indicate that TMDSC could improve the understanding of radiation-induced effects in polymers. (C) 2011 Elsevier Ltd. All rights reserved.",
journal = "Radiation Physics and Chemistry",
title = "A study of gamma-irradiated polyethylenes by temperature modulated differential scanning calorimetry",
volume = "81",
number = "9",
pages = "1374-1377",
doi = "10.1016/j.radphyschem.2011.11.054"
}
Galović, S., Šećerov, B. Lj., Trifunovic, S., Miličević, D. S.,& Suljovrujić, E. H.. (2012). A study of gamma-irradiated polyethylenes by temperature modulated differential scanning calorimetry. in Radiation Physics and Chemistry, 81(9), 1374-1377.
https://doi.org/10.1016/j.radphyschem.2011.11.054
Galović S, Šećerov BL, Trifunovic S, Miličević DS, Suljovrujić EH. A study of gamma-irradiated polyethylenes by temperature modulated differential scanning calorimetry. in Radiation Physics and Chemistry. 2012;81(9):1374-1377.
doi:10.1016/j.radphyschem.2011.11.054 .
Galović, Slobodanka, Šećerov, Bojana Lj., Trifunovic, S., Miličević, Dejan S., Suljovrujić, Edin H., "A study of gamma-irradiated polyethylenes by temperature modulated differential scanning calorimetry" in Radiation Physics and Chemistry, 81, no. 9 (2012):1374-1377,
https://doi.org/10.1016/j.radphyschem.2011.11.054 . .
7
7
6

Characterization of dosimeters used in radiation processing

Šećerov, Bojana; Janković, Ivana A.; Dramićanin, Miroslav

(Society of Physical Chemists of Serbia, 2012)

TY  - CONF
AU  - Šećerov, Bojana
AU  - Janković, Ivana A.
AU  - Dramićanin, Miroslav
PY  - 2012
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9307
AB  - Aérial L-alanine pellet dosimeter is characterized as the dispersion of dose
measurement values in order to determine the level of uncertainty caused by
dosimeter itself. The results of repeated measurements indicate that the uncertainty
of 1.2% could be attributed to the homogeneity of alanine in dosimeter pellets. It
was obtained by analyzing the results of measurements of the different dosimeters
from the same batch that the uncertainty due to difference in dosimeter mass is 1%.
The total uncertainty due to dosimeter itself is 1.5%.
PB  - Society of Physical Chemists of Serbia
C3  - Physical chemistry 2012 : 11th international conference on fundamental and applied aspects of physical chemistry
T1  - Characterization of dosimeters used in radiation processing
VL  - 1
SP  - 412
EP  - 414
UR  - https://hdl.handle.net/21.15107/rcub_vinar_9307
ER  - 
@conference{
author = "Šećerov, Bojana and Janković, Ivana A. and Dramićanin, Miroslav",
year = "2012",
abstract = "Aérial L-alanine pellet dosimeter is characterized as the dispersion of dose
measurement values in order to determine the level of uncertainty caused by
dosimeter itself. The results of repeated measurements indicate that the uncertainty
of 1.2% could be attributed to the homogeneity of alanine in dosimeter pellets. It
was obtained by analyzing the results of measurements of the different dosimeters
from the same batch that the uncertainty due to difference in dosimeter mass is 1%.
The total uncertainty due to dosimeter itself is 1.5%.",
publisher = "Society of Physical Chemists of Serbia",
journal = "Physical chemistry 2012 : 11th international conference on fundamental and applied aspects of physical chemistry",
title = "Characterization of dosimeters used in radiation processing",
volume = "1",
pages = "412-414",
url = "https://hdl.handle.net/21.15107/rcub_vinar_9307"
}
Šećerov, B., Janković, I. A.,& Dramićanin, M.. (2012). Characterization of dosimeters used in radiation processing. in Physical chemistry 2012 : 11th international conference on fundamental and applied aspects of physical chemistry
Society of Physical Chemists of Serbia., 1, 412-414.
https://hdl.handle.net/21.15107/rcub_vinar_9307
Šećerov B, Janković IA, Dramićanin M. Characterization of dosimeters used in radiation processing. in Physical chemistry 2012 : 11th international conference on fundamental and applied aspects of physical chemistry. 2012;1:412-414.
https://hdl.handle.net/21.15107/rcub_vinar_9307 .
Šećerov, Bojana, Janković, Ivana A., Dramićanin, Miroslav, "Characterization of dosimeters used in radiation processing" in Physical chemistry 2012 : 11th international conference on fundamental and applied aspects of physical chemistry, 1 (2012):412-414,
https://hdl.handle.net/21.15107/rcub_vinar_9307 .

Calibration of Routine Dosimeters in Radiation Processing: Validation Procedure for In-Plant Calibration

Šećerov, Bojana Lj.; Bačić, Goran G.

(2011)

TY  - JOUR
AU  - Šećerov, Bojana Lj.
AU  - Bačić, Goran G.
PY  - 2011
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/4635
AB  - The essential prerequisite of radiation dosimetry is to provide quality assurance and documentation that the irradiation procedure has been carried out according to the specification requirement of correct calibration of the chosen dosimetry system. At the Radiation Plant of the Vinca Institute of Nuclear Sciences we compared two recommended protocols of irradiation procedures in the calibration of dosimetry systems in radiation processing: (1) by irradiation of routine dosimeters (ethanol-chlorobenzene - ECB) at the calibration laboratory and (2), by in-plant calibration with alanine transfer - dosimeters. The critical point for in-plant calibration is irradiation geometry, so we carefully positioned the phantom carrying both dosimeters in order to minimize dose gradients across the sample. The analysis of results obtained showed that the difference among determined absorbed doses for the construction of calibration curves between these two methods, (alanine vs. ECB), is less than 1%. The difference in combined standard uncertainty for each calibration procedure is 0.1%. These results demonstrate that our in-plant calibration is as good as calibration by irradiation at the calibration laboratory and validates our placement of the irradiation phantom during irradiation.
T2  - Nuclear technology and radiation protection
T1  - Calibration of Routine Dosimeters in Radiation Processing: Validation Procedure for In-Plant Calibration
VL  - 26
IS  - 3
SP  - 271
EP  - 274
DO  - 10.2298/NTRP1103271S
ER  - 
@article{
author = "Šećerov, Bojana Lj. and Bačić, Goran G.",
year = "2011",
abstract = "The essential prerequisite of radiation dosimetry is to provide quality assurance and documentation that the irradiation procedure has been carried out according to the specification requirement of correct calibration of the chosen dosimetry system. At the Radiation Plant of the Vinca Institute of Nuclear Sciences we compared two recommended protocols of irradiation procedures in the calibration of dosimetry systems in radiation processing: (1) by irradiation of routine dosimeters (ethanol-chlorobenzene - ECB) at the calibration laboratory and (2), by in-plant calibration with alanine transfer - dosimeters. The critical point for in-plant calibration is irradiation geometry, so we carefully positioned the phantom carrying both dosimeters in order to minimize dose gradients across the sample. The analysis of results obtained showed that the difference among determined absorbed doses for the construction of calibration curves between these two methods, (alanine vs. ECB), is less than 1%. The difference in combined standard uncertainty for each calibration procedure is 0.1%. These results demonstrate that our in-plant calibration is as good as calibration by irradiation at the calibration laboratory and validates our placement of the irradiation phantom during irradiation.",
journal = "Nuclear technology and radiation protection",
title = "Calibration of Routine Dosimeters in Radiation Processing: Validation Procedure for In-Plant Calibration",
volume = "26",
number = "3",
pages = "271-274",
doi = "10.2298/NTRP1103271S"
}
Šećerov, B. Lj.,& Bačić, G. G.. (2011). Calibration of Routine Dosimeters in Radiation Processing: Validation Procedure for In-Plant Calibration. in Nuclear technology and radiation protection, 26(3), 271-274.
https://doi.org/10.2298/NTRP1103271S
Šećerov BL, Bačić GG. Calibration of Routine Dosimeters in Radiation Processing: Validation Procedure for In-Plant Calibration. in Nuclear technology and radiation protection. 2011;26(3):271-274.
doi:10.2298/NTRP1103271S .
Šećerov, Bojana Lj., Bačić, Goran G., "Calibration of Routine Dosimeters in Radiation Processing: Validation Procedure for In-Plant Calibration" in Nuclear technology and radiation protection, 26, no. 3 (2011):271-274,
https://doi.org/10.2298/NTRP1103271S . .
1
2

Dosimetry using HS GafChromic films the influence of readout light on sensitivity of dosimetry

Šećerov, Bojana Lj.; Dakovic, Marko; Borojević, Nenad; Bačić, Goran

(2011)

TY  - JOUR
AU  - Šećerov, Bojana Lj.
AU  - Dakovic, Marko
AU  - Borojević, Nenad
AU  - Bačić, Goran
PY  - 2011
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/4250
AB  - Various forms of Gafchromic films that are increasingly used for dosimetry in radiotherapy offer the prospect of reproducible and accurate high-resolution two-dimensional dose measurements, but there are many unresolved issues regarding the optimal choice of densitometric procedure used for the films optical density (OD) readout. There are conflicting requirements for scanners (sensitivity, availability, price) and commercial document scanners appears to be a reasonable option, hence we analyzed the measured sublinear dose response of these scanners. Using measured film absorption spectra we were able to make quantitative distinction between various factors affecting the sublinearity and to demonstrate that the dose response curve can be predicted for any selected light source used for scanning. We also used the commercial narrow bandpass filters in conjunction with document scanners to investigate whether such an inexpensive option can improve their sensitivity, but results were not encouraging. Finally, we analyzed the suitability of proposed fitting equations for the calibration of the dose response and found that their reliability largely depends on the dose range used for the calibration. (C) 2011 Elsevier B.V. All rights reserved.
T2  - Nuclear Instruments and Methods in Physics Research. Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment
T1  - Dosimetry using HS GafChromic films the influence of readout light on sensitivity of dosimetry
VL  - 633
IS  - 1
SP  - 66
EP  - 71
DO  - 10.1016/j.nima.2010.12.234
ER  - 
@article{
author = "Šećerov, Bojana Lj. and Dakovic, Marko and Borojević, Nenad and Bačić, Goran",
year = "2011",
abstract = "Various forms of Gafchromic films that are increasingly used for dosimetry in radiotherapy offer the prospect of reproducible and accurate high-resolution two-dimensional dose measurements, but there are many unresolved issues regarding the optimal choice of densitometric procedure used for the films optical density (OD) readout. There are conflicting requirements for scanners (sensitivity, availability, price) and commercial document scanners appears to be a reasonable option, hence we analyzed the measured sublinear dose response of these scanners. Using measured film absorption spectra we were able to make quantitative distinction between various factors affecting the sublinearity and to demonstrate that the dose response curve can be predicted for any selected light source used for scanning. We also used the commercial narrow bandpass filters in conjunction with document scanners to investigate whether such an inexpensive option can improve their sensitivity, but results were not encouraging. Finally, we analyzed the suitability of proposed fitting equations for the calibration of the dose response and found that their reliability largely depends on the dose range used for the calibration. (C) 2011 Elsevier B.V. All rights reserved.",
journal = "Nuclear Instruments and Methods in Physics Research. Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment",
title = "Dosimetry using HS GafChromic films the influence of readout light on sensitivity of dosimetry",
volume = "633",
number = "1",
pages = "66-71",
doi = "10.1016/j.nima.2010.12.234"
}
Šećerov, B. Lj., Dakovic, M., Borojević, N.,& Bačić, G.. (2011). Dosimetry using HS GafChromic films the influence of readout light on sensitivity of dosimetry. in Nuclear Instruments and Methods in Physics Research. Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment, 633(1), 66-71.
https://doi.org/10.1016/j.nima.2010.12.234
Šećerov BL, Dakovic M, Borojević N, Bačić G. Dosimetry using HS GafChromic films the influence of readout light on sensitivity of dosimetry. in Nuclear Instruments and Methods in Physics Research. Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment. 2011;633(1):66-71.
doi:10.1016/j.nima.2010.12.234 .
Šećerov, Bojana Lj., Dakovic, Marko, Borojević, Nenad, Bačić, Goran, "Dosimetry using HS GafChromic films the influence of readout light on sensitivity of dosimetry" in Nuclear Instruments and Methods in Physics Research. Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment, 633, no. 1 (2011):66-71,
https://doi.org/10.1016/j.nima.2010.12.234 . .
2
3
2

Notes on the calibration of routine dosimeters in radiation processing

Šećerov, Bojana; Bačić, Goran

(Society of Physical Chemists of Serbia, 2010)

TY  - CONF
AU  - Šećerov, Bojana
AU  - Bačić, Goran
PY  - 2010
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9322
AB  - The essential prerequisite of radiation dosimetry is to provide quality assurance and
documentation that the irradiation procedure has been carried out according to
specifications requirement of the correct calibration of the chosen dosimetry
system. In the Radiation Plant at the Vinča Institute, we compared two
recommended protocols in calibration of dosimetry systems in radiation
processing: (i) by using standardized routine dosimeters (ethanol-chlorobenzene
ECB) from the reference laboratory and (ii) by in-plant calibration with the alanine
transfer dosimeters. The analysis of results showed that our in-plant calibration is
as good as when standardized dosimeters are used, thus validating our irradiation
geometry in the irradiation process.
PB  - Society of Physical Chemists of Serbia
C3  - Physical chemistry 2010 : 10th international conference on fundamental and applied aspects of physical chemistry
T1  - Notes on the calibration of routine dosimeters in radiation processing
UR  - https://hdl.handle.net/21.15107/rcub_vinar_9322
ER  - 
@conference{
author = "Šećerov, Bojana and Bačić, Goran",
year = "2010",
abstract = "The essential prerequisite of radiation dosimetry is to provide quality assurance and
documentation that the irradiation procedure has been carried out according to
specifications requirement of the correct calibration of the chosen dosimetry
system. In the Radiation Plant at the Vinča Institute, we compared two
recommended protocols in calibration of dosimetry systems in radiation
processing: (i) by using standardized routine dosimeters (ethanol-chlorobenzene
ECB) from the reference laboratory and (ii) by in-plant calibration with the alanine
transfer dosimeters. The analysis of results showed that our in-plant calibration is
as good as when standardized dosimeters are used, thus validating our irradiation
geometry in the irradiation process.",
publisher = "Society of Physical Chemists of Serbia",
journal = "Physical chemistry 2010 : 10th international conference on fundamental and applied aspects of physical chemistry",
title = "Notes on the calibration of routine dosimeters in radiation processing",
url = "https://hdl.handle.net/21.15107/rcub_vinar_9322"
}
Šećerov, B.,& Bačić, G.. (2010). Notes on the calibration of routine dosimeters in radiation processing. in Physical chemistry 2010 : 10th international conference on fundamental and applied aspects of physical chemistry
Society of Physical Chemists of Serbia..
https://hdl.handle.net/21.15107/rcub_vinar_9322
Šećerov B, Bačić G. Notes on the calibration of routine dosimeters in radiation processing. in Physical chemistry 2010 : 10th international conference on fundamental and applied aspects of physical chemistry. 2010;.
https://hdl.handle.net/21.15107/rcub_vinar_9322 .
Šećerov, Bojana, Bačić, Goran, "Notes on the calibration of routine dosimeters in radiation processing" in Physical chemistry 2010 : 10th international conference on fundamental and applied aspects of physical chemistry (2010),
https://hdl.handle.net/21.15107/rcub_vinar_9322 .

Cranial irradiation modulates hypothalamic-pituitary-adrenal axis activity and corticosteroid receptor expression in the hippocampus of juvenile rat

Velickovic, Natasa; Đorđević, Ana D.; Drakulić, Dunja R.; Stanojević, Ivana; Šećerov, Bojana Lj.; Horvat, Anica

(2009)

TY  - JOUR
AU  - Velickovic, Natasa
AU  - Đorđević, Ana D.
AU  - Drakulić, Dunja R.
AU  - Stanojević, Ivana
AU  - Šećerov, Bojana Lj.
AU  - Horvat, Anica
PY  - 2009
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2559
AB  - Glucocorticoids, essential for normal,hypothalamic-pituitary-adrenal (HPA) axis activity, exert their action on the hippocampus through two types of corticosteroid receptors: the glucocorticoid receptor (GR) and the mineralocorticoid receptor (MR). Recent studies report that exposure of juvenile rats to cranial irradiation adversely affects HPA axis stability leading to its activation along with radiation-induced inflammation. This study was aimed to examine the acute effects of radiation on HPA axis activity and hippocampal corticosteroid receptor expression in 18-day-old rats. Since immobilization was part of irradiation procedure, both irradiated and sham-irradiated animals were exposed to this unavoidable stress. Our results demonstrate that the irradiated rats exhibited different pattern of corticosteroid receptor expression and hormone levels compared to respective controls. These differences included upregulation of GR protein in the hippocampus with a concomitant elevation of GR mRNA and an increase in circulating level of corticosterone. In addition, the expression of MR, both at the level of protein and gene expression, was not altered. Taken together, this study demonstrates that cranial irradiation in juvenile rats leads to enhanced HPA axis activity and increased relative GR/MR ratio in hippocampus. The present paper intends to show that neuroendocrine response of normal brain tissue to localized irradiation comprise both activation of HPA axis and altered corticosteroid receptor balance, probably as consequence of innate immune activation.
T2  - General Physiology and Biophysics
T1  - Cranial irradiation modulates hypothalamic-pituitary-adrenal axis activity and corticosteroid receptor expression in the hippocampus of juvenile rat
VL  - 28
IS  - SI
SP  - 219
EP  - 227
UR  - https://hdl.handle.net/21.15107/rcub_vinar_2559
ER  - 
@article{
author = "Velickovic, Natasa and Đorđević, Ana D. and Drakulić, Dunja R. and Stanojević, Ivana and Šećerov, Bojana Lj. and Horvat, Anica",
year = "2009",
abstract = "Glucocorticoids, essential for normal,hypothalamic-pituitary-adrenal (HPA) axis activity, exert their action on the hippocampus through two types of corticosteroid receptors: the glucocorticoid receptor (GR) and the mineralocorticoid receptor (MR). Recent studies report that exposure of juvenile rats to cranial irradiation adversely affects HPA axis stability leading to its activation along with radiation-induced inflammation. This study was aimed to examine the acute effects of radiation on HPA axis activity and hippocampal corticosteroid receptor expression in 18-day-old rats. Since immobilization was part of irradiation procedure, both irradiated and sham-irradiated animals were exposed to this unavoidable stress. Our results demonstrate that the irradiated rats exhibited different pattern of corticosteroid receptor expression and hormone levels compared to respective controls. These differences included upregulation of GR protein in the hippocampus with a concomitant elevation of GR mRNA and an increase in circulating level of corticosterone. In addition, the expression of MR, both at the level of protein and gene expression, was not altered. Taken together, this study demonstrates that cranial irradiation in juvenile rats leads to enhanced HPA axis activity and increased relative GR/MR ratio in hippocampus. The present paper intends to show that neuroendocrine response of normal brain tissue to localized irradiation comprise both activation of HPA axis and altered corticosteroid receptor balance, probably as consequence of innate immune activation.",
journal = "General Physiology and Biophysics",
title = "Cranial irradiation modulates hypothalamic-pituitary-adrenal axis activity and corticosteroid receptor expression in the hippocampus of juvenile rat",
volume = "28",
number = "SI",
pages = "219-227",
url = "https://hdl.handle.net/21.15107/rcub_vinar_2559"
}
Velickovic, N., Đorđević, A. D., Drakulić, D. R., Stanojević, I., Šećerov, B. Lj.,& Horvat, A.. (2009). Cranial irradiation modulates hypothalamic-pituitary-adrenal axis activity and corticosteroid receptor expression in the hippocampus of juvenile rat. in General Physiology and Biophysics, 28(SI), 219-227.
https://hdl.handle.net/21.15107/rcub_vinar_2559
Velickovic N, Đorđević AD, Drakulić DR, Stanojević I, Šećerov BL, Horvat A. Cranial irradiation modulates hypothalamic-pituitary-adrenal axis activity and corticosteroid receptor expression in the hippocampus of juvenile rat. in General Physiology and Biophysics. 2009;28(SI):219-227.
https://hdl.handle.net/21.15107/rcub_vinar_2559 .
Velickovic, Natasa, Đorđević, Ana D., Drakulić, Dunja R., Stanojević, Ivana, Šećerov, Bojana Lj., Horvat, Anica, "Cranial irradiation modulates hypothalamic-pituitary-adrenal axis activity and corticosteroid receptor expression in the hippocampus of juvenile rat" in General Physiology and Biophysics, 28, no. SI (2009):219-227,
https://hdl.handle.net/21.15107/rcub_vinar_2559 .
8

Characterization of gamma irradiated ethylene-norbornene copolymer using FTIR, UV-Vis and DSC techniques

Šećerov, Bojana Lj.; Marinović-Cincović, Milena; Popovic, S.; Nedić, Zoran; Kačarević-Popović, Zorica M.

(2008)

TY  - JOUR
AU  - Šećerov, Bojana Lj.
AU  - Marinović-Cincović, Milena
AU  - Popovic, S.
AU  - Nedić, Zoran
AU  - Kačarević-Popović, Zorica M.
PY  - 2008
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3380
AB  - Due to their new combination of properties and shortage of the experimental data, the radiolysis of a new class of materials, cyclo-olefin copolymers (COC), which are polymerized from norbornene and ethylene using metallocene catalysts, is of great interest to the study of radiation chemistry and physics of polymeric systems. Ethylene-norbornene copolymer, bare and containing 0.45 wt % of the hindered phenolic type of an antioxidant (IRGANOX 1010) was subjected to gamma irradiation (100, 200 and 500 kGy) in the presence of air and in water. The irradiated copolymer was studied using FTIR, UV-vis spectrophotometric and gel content analysis. The insoluble fraction was formed in copolymer irradiated in water with 500 kGy, in bare 36% and in copolymer with an antioxidant 23%. The radiation induced changes in the molecular structure were correlated to the specific heat capacity and the glass transition temperature measured by DSC method.
T2  - Polymer Bulletin
T1  - Characterization of gamma irradiated ethylene-norbornene copolymer using FTIR, UV-Vis and DSC techniques
VL  - 60
IS  - 2-3
SP  - 313
EP  - 322
DO  - 10.1007/s00289-007-0867-5
ER  - 
@article{
author = "Šećerov, Bojana Lj. and Marinović-Cincović, Milena and Popovic, S. and Nedić, Zoran and Kačarević-Popović, Zorica M.",
year = "2008",
abstract = "Due to their new combination of properties and shortage of the experimental data, the radiolysis of a new class of materials, cyclo-olefin copolymers (COC), which are polymerized from norbornene and ethylene using metallocene catalysts, is of great interest to the study of radiation chemistry and physics of polymeric systems. Ethylene-norbornene copolymer, bare and containing 0.45 wt % of the hindered phenolic type of an antioxidant (IRGANOX 1010) was subjected to gamma irradiation (100, 200 and 500 kGy) in the presence of air and in water. The irradiated copolymer was studied using FTIR, UV-vis spectrophotometric and gel content analysis. The insoluble fraction was formed in copolymer irradiated in water with 500 kGy, in bare 36% and in copolymer with an antioxidant 23%. The radiation induced changes in the molecular structure were correlated to the specific heat capacity and the glass transition temperature measured by DSC method.",
journal = "Polymer Bulletin",
title = "Characterization of gamma irradiated ethylene-norbornene copolymer using FTIR, UV-Vis and DSC techniques",
volume = "60",
number = "2-3",
pages = "313-322",
doi = "10.1007/s00289-007-0867-5"
}
Šećerov, B. Lj., Marinović-Cincović, M., Popovic, S., Nedić, Z.,& Kačarević-Popović, Z. M.. (2008). Characterization of gamma irradiated ethylene-norbornene copolymer using FTIR, UV-Vis and DSC techniques. in Polymer Bulletin, 60(2-3), 313-322.
https://doi.org/10.1007/s00289-007-0867-5
Šećerov BL, Marinović-Cincović M, Popovic S, Nedić Z, Kačarević-Popović ZM. Characterization of gamma irradiated ethylene-norbornene copolymer using FTIR, UV-Vis and DSC techniques. in Polymer Bulletin. 2008;60(2-3):313-322.
doi:10.1007/s00289-007-0867-5 .
Šećerov, Bojana Lj., Marinović-Cincović, Milena, Popovic, S., Nedić, Zoran, Kačarević-Popović, Zorica M., "Characterization of gamma irradiated ethylene-norbornene copolymer using FTIR, UV-Vis and DSC techniques" in Polymer Bulletin, 60, no. 2-3 (2008):313-322,
https://doi.org/10.1007/s00289-007-0867-5 . .
14
14
16

Combustion Synthesis and Characterization of CeO2 Nanopowder

Šećerov, Bojana Lj.; Andrić, Željka; Abazović, Nadica; Krsmanović, Radenka; Mitrić, Miodrag; Montone, Amelia; Dramićanin, Miroslav

(2008)

TY  - JOUR
AU  - Šećerov, Bojana Lj.
AU  - Andrić, Željka
AU  - Abazović, Nadica
AU  - Krsmanović, Radenka
AU  - Mitrić, Miodrag
AU  - Montone, Amelia
AU  - Dramićanin, Miroslav
PY  - 2008
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3545
AB  - Modified combustion procedure, named as polymer complex solution method (PCS), was used for synthesis of CeO2 nanopowder. As fuel was employed polyethylene glycol (PEG) with average molecular weight 200. Post-synthesis thermal treatments were done at 800 degrees C for 2 hours. X-ray powder diffraction, electron microscopy (SEM and TEM), laser light scattering, infrared spectroscopy, UV-VIS diffuse reflectance spectroscopy and luminescence spectroscopy were used as characterization methods. The objectives were to investigate the structure and morphology of the synthesized powder, in particular the aggregation and particle size distribution, and its luminescence properties. Photoluminescent properties of CeO2 nanopowder were determined from its emission and excitation spectra. In the excitation spectra two lines were present: one at 322 nm and other at 356 nm. Two lines were also visible in the emission spectra, one at 427 nm and other at 492 nm. Violet emission placed at 427 nm and excitation at 356 nm corresponded to D-5(1) - GT F-4(1) transition of cerium trivalent ion. A UV-VIS diffuse reflectance spectrum shows the absorption edge at 375 nm. The observed spectral blue shift revealed the presence of fine crystallites which escape XRD detection. The presented results demonstrate that this simple preparation technique provides well crystallized nanoparticles of CeO2.
T2  - Acta Chimica Slovenica
T1  - Combustion Synthesis and Characterization of CeO2 Nanopowder
VL  - 55
IS  - 3
SP  - 486
EP  - 491
UR  - https://hdl.handle.net/21.15107/rcub_vinar_3545
ER  - 
@article{
author = "Šećerov, Bojana Lj. and Andrić, Željka and Abazović, Nadica and Krsmanović, Radenka and Mitrić, Miodrag and Montone, Amelia and Dramićanin, Miroslav",
year = "2008",
abstract = "Modified combustion procedure, named as polymer complex solution method (PCS), was used for synthesis of CeO2 nanopowder. As fuel was employed polyethylene glycol (PEG) with average molecular weight 200. Post-synthesis thermal treatments were done at 800 degrees C for 2 hours. X-ray powder diffraction, electron microscopy (SEM and TEM), laser light scattering, infrared spectroscopy, UV-VIS diffuse reflectance spectroscopy and luminescence spectroscopy were used as characterization methods. The objectives were to investigate the structure and morphology of the synthesized powder, in particular the aggregation and particle size distribution, and its luminescence properties. Photoluminescent properties of CeO2 nanopowder were determined from its emission and excitation spectra. In the excitation spectra two lines were present: one at 322 nm and other at 356 nm. Two lines were also visible in the emission spectra, one at 427 nm and other at 492 nm. Violet emission placed at 427 nm and excitation at 356 nm corresponded to D-5(1) - GT F-4(1) transition of cerium trivalent ion. A UV-VIS diffuse reflectance spectrum shows the absorption edge at 375 nm. The observed spectral blue shift revealed the presence of fine crystallites which escape XRD detection. The presented results demonstrate that this simple preparation technique provides well crystallized nanoparticles of CeO2.",
journal = "Acta Chimica Slovenica",
title = "Combustion Synthesis and Characterization of CeO2 Nanopowder",
volume = "55",
number = "3",
pages = "486-491",
url = "https://hdl.handle.net/21.15107/rcub_vinar_3545"
}
Šećerov, B. Lj., Andrić, Ž., Abazović, N., Krsmanović, R., Mitrić, M., Montone, A.,& Dramićanin, M.. (2008). Combustion Synthesis and Characterization of CeO2 Nanopowder. in Acta Chimica Slovenica, 55(3), 486-491.
https://hdl.handle.net/21.15107/rcub_vinar_3545
Šećerov BL, Andrić Ž, Abazović N, Krsmanović R, Mitrić M, Montone A, Dramićanin M. Combustion Synthesis and Characterization of CeO2 Nanopowder. in Acta Chimica Slovenica. 2008;55(3):486-491.
https://hdl.handle.net/21.15107/rcub_vinar_3545 .
Šećerov, Bojana Lj., Andrić, Željka, Abazović, Nadica, Krsmanović, Radenka, Mitrić, Miodrag, Montone, Amelia, Dramićanin, Miroslav, "Combustion Synthesis and Characterization of CeO2 Nanopowder" in Acta Chimica Slovenica, 55, no. 3 (2008):486-491,
https://hdl.handle.net/21.15107/rcub_vinar_3545 .
11
14

Spin-trapping of oxygen free radicals in chemical and biological systems: New traps, radicals and possibilities

Bačić, Goran; Spasojević, Ivan; Šećerov, Bojana Lj.; Mojovic, Milos

(2008)

TY  - JOUR
AU  - Bačić, Goran
AU  - Spasojević, Ivan
AU  - Šećerov, Bojana Lj.
AU  - Mojovic, Milos
PY  - 2008
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/6755
AB  - The choice of the spin-trap that is to be applied in any EPR study represents the crossroad between a comprehensive investigation and an ordinary quantification of production of radicals. So, the scope of our study was to compare the performance of different spin-traps for qualitative analysis of radical-generating systems, and their ability to recognize previously unnoticed radicals. In addition, we present a brief account of the difficulties involved in the detection of oxygen-centered radicals in chemical and biological systems accompanied by the rationale for using the EPR spin-trapping technique in quantitative studies of such reactive species. Certain technical aspects of EPR experiments related to efficient trapping of free radicals in biochemical systems are also discussed. As an example we present here results obtained using EPR spectroscopy and the spin-trap DEPMPO, which show that the Fenton reaction, as well as various biological systems generate a previously unappreciated hydrogen (H-center dot) atom. (C) 2007 Elsevier B.V. All rights reserved.
T2  - Spectrochimica Acta. Part A: Molecular and Biomolecular Spectroscopy
T1  - Spin-trapping of oxygen free radicals in chemical and biological systems: New traps, radicals and possibilities
VL  - 69
IS  - 5
SP  - 1354
EP  - 1366
DO  - 10.1016/j.saa.2007.09.047
ER  - 
@article{
author = "Bačić, Goran and Spasojević, Ivan and Šećerov, Bojana Lj. and Mojovic, Milos",
year = "2008",
abstract = "The choice of the spin-trap that is to be applied in any EPR study represents the crossroad between a comprehensive investigation and an ordinary quantification of production of radicals. So, the scope of our study was to compare the performance of different spin-traps for qualitative analysis of radical-generating systems, and their ability to recognize previously unnoticed radicals. In addition, we present a brief account of the difficulties involved in the detection of oxygen-centered radicals in chemical and biological systems accompanied by the rationale for using the EPR spin-trapping technique in quantitative studies of such reactive species. Certain technical aspects of EPR experiments related to efficient trapping of free radicals in biochemical systems are also discussed. As an example we present here results obtained using EPR spectroscopy and the spin-trap DEPMPO, which show that the Fenton reaction, as well as various biological systems generate a previously unappreciated hydrogen (H-center dot) atom. (C) 2007 Elsevier B.V. All rights reserved.",
journal = "Spectrochimica Acta. Part A: Molecular and Biomolecular Spectroscopy",
title = "Spin-trapping of oxygen free radicals in chemical and biological systems: New traps, radicals and possibilities",
volume = "69",
number = "5",
pages = "1354-1366",
doi = "10.1016/j.saa.2007.09.047"
}
Bačić, G., Spasojević, I., Šećerov, B. Lj.,& Mojovic, M.. (2008). Spin-trapping of oxygen free radicals in chemical and biological systems: New traps, radicals and possibilities. in Spectrochimica Acta. Part A: Molecular and Biomolecular Spectroscopy, 69(5), 1354-1366.
https://doi.org/10.1016/j.saa.2007.09.047
Bačić G, Spasojević I, Šećerov BL, Mojovic M. Spin-trapping of oxygen free radicals in chemical and biological systems: New traps, radicals and possibilities. in Spectrochimica Acta. Part A: Molecular and Biomolecular Spectroscopy. 2008;69(5):1354-1366.
doi:10.1016/j.saa.2007.09.047 .
Bačić, Goran, Spasojević, Ivan, Šećerov, Bojana Lj., Mojovic, Milos, "Spin-trapping of oxygen free radicals in chemical and biological systems: New traps, radicals and possibilities" in Spectrochimica Acta. Part A: Molecular and Biomolecular Spectroscopy, 69, no. 5 (2008):1354-1366,
https://doi.org/10.1016/j.saa.2007.09.047 . .
3
89
78
82

Comparison of dichromate and ethanol-chlorobenzene dosimeters in high dose radiation processing

Šećerov, Bojana Lj.; Bačić, Goran

(2008)

TY  - JOUR
AU  - Šećerov, Bojana Lj.
AU  - Bačić, Goran
PY  - 2008
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3526
AB  - Dichromate and ethanol-chlorobenzene dosimeters were studied in conditions of annual temperature changes during process control at the Radiation Unit of the Vinca Institute. Measurements were performed in February (10-14 degrees C) and August (22-35 degrees C) for the dose range 10-50 kGy. The difference between measurements using these dosimeters is in agreement with the previous laboratory studies of temperature effect on the dose response of a dichromate dosimeter. The absorbed doses measured by these two dosimeters are in good agreement and the difference is within a limit of 3% for the studied dose range. The uncertainties of dose measurements using dichromate dosimeter arising from irradiation during annual temperature changes appear to be well within acceptable limits indicating that this dosimeter can be used as a routine dosimeter.
T2  - Nukleonika
T1  - Comparison of dichromate and ethanol-chlorobenzene dosimeters in high dose radiation processing
VL  - 53
IS  - 3
SP  - 85
EP  - 87
UR  - https://hdl.handle.net/21.15107/rcub_vinar_3526
ER  - 
@article{
author = "Šećerov, Bojana Lj. and Bačić, Goran",
year = "2008",
abstract = "Dichromate and ethanol-chlorobenzene dosimeters were studied in conditions of annual temperature changes during process control at the Radiation Unit of the Vinca Institute. Measurements were performed in February (10-14 degrees C) and August (22-35 degrees C) for the dose range 10-50 kGy. The difference between measurements using these dosimeters is in agreement with the previous laboratory studies of temperature effect on the dose response of a dichromate dosimeter. The absorbed doses measured by these two dosimeters are in good agreement and the difference is within a limit of 3% for the studied dose range. The uncertainties of dose measurements using dichromate dosimeter arising from irradiation during annual temperature changes appear to be well within acceptable limits indicating that this dosimeter can be used as a routine dosimeter.",
journal = "Nukleonika",
title = "Comparison of dichromate and ethanol-chlorobenzene dosimeters in high dose radiation processing",
volume = "53",
number = "3",
pages = "85-87",
url = "https://hdl.handle.net/21.15107/rcub_vinar_3526"
}
Šećerov, B. Lj.,& Bačić, G.. (2008). Comparison of dichromate and ethanol-chlorobenzene dosimeters in high dose radiation processing. in Nukleonika, 53(3), 85-87.
https://hdl.handle.net/21.15107/rcub_vinar_3526
Šećerov BL, Bačić G. Comparison of dichromate and ethanol-chlorobenzene dosimeters in high dose radiation processing. in Nukleonika. 2008;53(3):85-87.
https://hdl.handle.net/21.15107/rcub_vinar_3526 .
Šećerov, Bojana Lj., Bačić, Goran, "Comparison of dichromate and ethanol-chlorobenzene dosimeters in high dose radiation processing" in Nukleonika, 53, no. 3 (2008):85-87,
https://hdl.handle.net/21.15107/rcub_vinar_3526 .
1

Investigation on the crystallization process of Eu3+: CaSiO3 gel using optical and thermal methods

Andrić, Željka; Krsmanović, Radenka; Marinović-Cincović, Milena; Dramićanin, Tatjana; Šećerov, Bojana Lj.; Dramićanin, Miroslav

(2007)

TY  - JOUR
AU  - Andrić, Željka
AU  - Krsmanović, Radenka
AU  - Marinović-Cincović, Milena
AU  - Dramićanin, Tatjana
AU  - Šećerov, Bojana Lj.
AU  - Dramićanin, Miroslav
PY  - 2007
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/6710
AB  - Alkoxy sol-gel technique is an important preparation method for production of rare-earth based phosphors. Crystallization of gel provides a way to prepare phosphors on lower working temperatures than those required for the solid state reactions. CaSiO3 gel samples were obtained through hydrolysis-condensation reactions of tetraethylorthosilicate as silica source. In this work we studied the process of crystallization of Eu3+-activated CaSiO3 gel and decomposition of organic precursors by means of thermal analysis and infrared spectroscopy. Results of scanning electron microscopy and energy-dispersion spectrometry are used to check chemical composition and morphology of synthesized material. Emission spectra and emission lifetime measurements are performed to investigate luminescence properties of Eu3+ doped CaSiO3 powder.
T2  - Acta Physica Polonica A
T1  - Investigation on the crystallization process of Eu3+: CaSiO3 gel using optical and thermal methods
VL  - 112
IS  - 5
SP  - 969
EP  - 974
DO  - 10.12693/APhysPolA.112.969
ER  - 
@article{
author = "Andrić, Željka and Krsmanović, Radenka and Marinović-Cincović, Milena and Dramićanin, Tatjana and Šećerov, Bojana Lj. and Dramićanin, Miroslav",
year = "2007",
abstract = "Alkoxy sol-gel technique is an important preparation method for production of rare-earth based phosphors. Crystallization of gel provides a way to prepare phosphors on lower working temperatures than those required for the solid state reactions. CaSiO3 gel samples were obtained through hydrolysis-condensation reactions of tetraethylorthosilicate as silica source. In this work we studied the process of crystallization of Eu3+-activated CaSiO3 gel and decomposition of organic precursors by means of thermal analysis and infrared spectroscopy. Results of scanning electron microscopy and energy-dispersion spectrometry are used to check chemical composition and morphology of synthesized material. Emission spectra and emission lifetime measurements are performed to investigate luminescence properties of Eu3+ doped CaSiO3 powder.",
journal = "Acta Physica Polonica A",
title = "Investigation on the crystallization process of Eu3+: CaSiO3 gel using optical and thermal methods",
volume = "112",
number = "5",
pages = "969-974",
doi = "10.12693/APhysPolA.112.969"
}
Andrić, Ž., Krsmanović, R., Marinović-Cincović, M., Dramićanin, T., Šećerov, B. Lj.,& Dramićanin, M.. (2007). Investigation on the crystallization process of Eu3+: CaSiO3 gel using optical and thermal methods. in Acta Physica Polonica A, 112(5), 969-974.
https://doi.org/10.12693/APhysPolA.112.969
Andrić Ž, Krsmanović R, Marinović-Cincović M, Dramićanin T, Šećerov BL, Dramićanin M. Investigation on the crystallization process of Eu3+: CaSiO3 gel using optical and thermal methods. in Acta Physica Polonica A. 2007;112(5):969-974.
doi:10.12693/APhysPolA.112.969 .
Andrić, Željka, Krsmanović, Radenka, Marinović-Cincović, Milena, Dramićanin, Tatjana, Šećerov, Bojana Lj., Dramićanin, Miroslav, "Investigation on the crystallization process of Eu3+: CaSiO3 gel using optical and thermal methods" in Acta Physica Polonica A, 112, no. 5 (2007):969-974,
https://doi.org/10.12693/APhysPolA.112.969 . .
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6

DOSIMETRY USING HS GafChromic FILMS The influence of readout light on sensitivity of dosimetry

Šećerov, Bojana Lj.; Daković, Marko; Sarić, M.; Bačić, Goran; Borojević, Nenad

(Society of Physical Chemists of Serbia, 2006)

TY  - CONF
AU  - Šećerov, Bojana Lj.
AU  - Daković, Marko
AU  - Sarić, M.
AU  - Bačić, Goran
AU  - Borojević, Nenad
PY  - 2006
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9445
AB  - The goal of this study is to compare the sensitometric curves for HS model of GafChromic film using different dose read-out systems. Two commercial densitometers using fluorescent light source were tested and compared with results obtained using spectrophotometry. It was found that sublinear response of densitometers is due to the polychromaticity of emitted light and that response curve can be predicted by analysing absorption spectra of the film.
PB  - Society of Physical Chemists of Serbia
C3  - Physical chemistry 2006: 8th international conference on fundemental and applied aspract of physical chemistry
T1  - DOSIMETRY USING HS GafChromic FILMS The influence of readout light on sensitivity of dosimetry
SP  - 463
EP  - 465
UR  - https://hdl.handle.net/21.15107/rcub_vinar_9445
ER  - 
@conference{
author = "Šećerov, Bojana Lj. and Daković, Marko and Sarić, M. and Bačić, Goran and Borojević, Nenad",
year = "2006",
abstract = "The goal of this study is to compare the sensitometric curves for HS model of GafChromic film using different dose read-out systems. Two commercial densitometers using fluorescent light source were tested and compared with results obtained using spectrophotometry. It was found that sublinear response of densitometers is due to the polychromaticity of emitted light and that response curve can be predicted by analysing absorption spectra of the film.",
publisher = "Society of Physical Chemists of Serbia",
journal = "Physical chemistry 2006: 8th international conference on fundemental and applied aspract of physical chemistry",
title = "DOSIMETRY USING HS GafChromic FILMS The influence of readout light on sensitivity of dosimetry",
pages = "463-465",
url = "https://hdl.handle.net/21.15107/rcub_vinar_9445"
}
Šećerov, B. Lj., Daković, M., Sarić, M., Bačić, G.,& Borojević, N.. (2006). DOSIMETRY USING HS GafChromic FILMS The influence of readout light on sensitivity of dosimetry. in Physical chemistry 2006: 8th international conference on fundemental and applied aspract of physical chemistry
Society of Physical Chemists of Serbia., 463-465.
https://hdl.handle.net/21.15107/rcub_vinar_9445
Šećerov BL, Daković M, Sarić M, Bačić G, Borojević N. DOSIMETRY USING HS GafChromic FILMS The influence of readout light on sensitivity of dosimetry. in Physical chemistry 2006: 8th international conference on fundemental and applied aspract of physical chemistry. 2006;:463-465.
https://hdl.handle.net/21.15107/rcub_vinar_9445 .
Šećerov, Bojana Lj., Daković, Marko, Sarić, M., Bačić, Goran, Borojević, Nenad, "DOSIMETRY USING HS GafChromic FILMS The influence of readout light on sensitivity of dosimetry" in Physical chemistry 2006: 8th international conference on fundemental and applied aspract of physical chemistry (2006):463-465,
https://hdl.handle.net/21.15107/rcub_vinar_9445 .

Influence of the irradiation conditions on the effect of radiation on polyethylene

Kačarević-Popović, Zorica M.; Kostoski, Dušan; Novaković, L; Miljević, Nada R.; Šećerov, Bojana Lj.

(2004)

TY  - JOUR
AU  - Kačarević-Popović, Zorica M.
AU  - Kostoski, Dušan
AU  - Novaković, L
AU  - Miljević, Nada R.
AU  - Šećerov, Bojana Lj.
PY  - 2004
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2857
AB  - Two types of polyethylene, low density (LDPE) and high density (HDPE), as well as low density polyethylene containing an antioxidant were subjected to gamma-irradiation in the presence of air and in water. The irradiated polymers were studied using IR spectrophotometric analysis. The radiation induced oxidative degradation was followed through the formation of oxygen containing groups by the development of bands in the 1850-1650 cm(-1) region and double bonds formation by the development of bands in the 1050-850 cm(-1) region. The crosslinking efficiency was determined by measuring the gel content by extraction with xylene. The radiation induced changes in the molecular structure, evolution of oxygen containing species and formation, of vinyl double bonds as well as of the crosslinking efficiency are discussed in terms of the properties of the polymers in an electric field of low strength.
T2  - Journal of the Serbian Chemical Society
T1  - Influence of the irradiation conditions on the effect of radiation on polyethylene
VL  - 69
IS  - 12
SP  - 1029
EP  - 1041
DO  - 10.2298/JSC0412029K
ER  - 
@article{
author = "Kačarević-Popović, Zorica M. and Kostoski, Dušan and Novaković, L and Miljević, Nada R. and Šećerov, Bojana Lj.",
year = "2004",
abstract = "Two types of polyethylene, low density (LDPE) and high density (HDPE), as well as low density polyethylene containing an antioxidant were subjected to gamma-irradiation in the presence of air and in water. The irradiated polymers were studied using IR spectrophotometric analysis. The radiation induced oxidative degradation was followed through the formation of oxygen containing groups by the development of bands in the 1850-1650 cm(-1) region and double bonds formation by the development of bands in the 1050-850 cm(-1) region. The crosslinking efficiency was determined by measuring the gel content by extraction with xylene. The radiation induced changes in the molecular structure, evolution of oxygen containing species and formation, of vinyl double bonds as well as of the crosslinking efficiency are discussed in terms of the properties of the polymers in an electric field of low strength.",
journal = "Journal of the Serbian Chemical Society",
title = "Influence of the irradiation conditions on the effect of radiation on polyethylene",
volume = "69",
number = "12",
pages = "1029-1041",
doi = "10.2298/JSC0412029K"
}
Kačarević-Popović, Z. M., Kostoski, D., Novaković, L., Miljević, N. R.,& Šećerov, B. Lj.. (2004). Influence of the irradiation conditions on the effect of radiation on polyethylene. in Journal of the Serbian Chemical Society, 69(12), 1029-1041.
https://doi.org/10.2298/JSC0412029K
Kačarević-Popović ZM, Kostoski D, Novaković L, Miljević NR, Šećerov BL. Influence of the irradiation conditions on the effect of radiation on polyethylene. in Journal of the Serbian Chemical Society. 2004;69(12):1029-1041.
doi:10.2298/JSC0412029K .
Kačarević-Popović, Zorica M., Kostoski, Dušan, Novaković, L, Miljević, Nada R., Šećerov, Bojana Lj., "Influence of the irradiation conditions on the effect of radiation on polyethylene" in Journal of the Serbian Chemical Society, 69, no. 12 (2004):1029-1041,
https://doi.org/10.2298/JSC0412029K . .
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21

New applications of radiochromatic films in radiation pysics

Stančić, V; Šećerov, Bojana Lj.

(2002)

TY  - CONF
AU  - Stančić, V
AU  - Šećerov, Bojana Lj.
PY  - 2002
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/6391
AB  - New methods for evaluating the energy spectrum of a source generating the radiation field, based on space-dependent flux distribution measured, data is proposed. The measured data are assumed to be obtained by using radiochromatic films. Mathematical modelling is defined as reversed transport problem. The semigroup method is proposed to reverse the transport problem.
T1  - New applications of radiochromatic films in radiation pysics
SP  - 71
EP  - 74
UR  - https://hdl.handle.net/21.15107/rcub_vinar_6391
ER  - 
@conference{
author = "Stančić, V and Šećerov, Bojana Lj.",
year = "2002",
abstract = "New methods for evaluating the energy spectrum of a source generating the radiation field, based on space-dependent flux distribution measured, data is proposed. The measured data are assumed to be obtained by using radiochromatic films. Mathematical modelling is defined as reversed transport problem. The semigroup method is proposed to reverse the transport problem.",
title = "New applications of radiochromatic films in radiation pysics",
pages = "71-74",
url = "https://hdl.handle.net/21.15107/rcub_vinar_6391"
}
Stančić, V.,& Šećerov, B. Lj.. (2002). New applications of radiochromatic films in radiation pysics. , 71-74.
https://hdl.handle.net/21.15107/rcub_vinar_6391
Stančić V, Šećerov BL. New applications of radiochromatic films in radiation pysics. 2002;:71-74.
https://hdl.handle.net/21.15107/rcub_vinar_6391 .
Stančić, V, Šećerov, Bojana Lj., "New applications of radiochromatic films in radiation pysics" (2002):71-74,
https://hdl.handle.net/21.15107/rcub_vinar_6391 .