TY  - JOUR
AU  - Joksić, Gordana
AU  - Valenta-Šobot, Ana
AU  - Filipović Tričković, Jelena G.
AU  - Maletić, Dejan
AU  - Puač, Nevena
AU  - Malović, Gordana N.
AU  - Petrović, Zoran Lj.
AU  - Lazović, Saša
PY  - 2019
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8178
AB  - In this study we evaluate apoptosis time window of primary fibroblasts treated with cold atmospheric plasma (CAP), power range 0.4-1.4 W, for 30 sec, using γ-H2AX phosphorylation assay and flow cytometry. In contrast to irradiation where maximum of γ-H2AX foci appeared 30 min after irradiation and apoptosis 24 h later irrespective of radiation dose, treatment with CAP (power of 0.4 and 0.6) induces maximum of γ-H2AX foci 2 h after treatment. Apoptosis occurred in a power-dependent manner, with time shift of 2-3 h. Besides power-dependent time shift in apoptosis induction, apoptosis time window is the same and lasts for 2 h. © 2019, Indian Academy of Sciences.
T2  - Current Science
T1  - Apoptosis time window induced by cold atmospheric plasma: Comparison with ionizing radiation
VL  - 116
IS  - 7
SP  - 1229
EP  - 1233
DO  - 10.18520/cs/v116/i7/1229-1233
ER  - 

@article{
author = "Joksić, Gordana and Valenta-Šobot, Ana and Filipović Tričković, Jelena G. and Maletić, Dejan and Puač, Nevena and Malović, Gordana N. and Petrović, Zoran Lj. and Lazović, Saša",
year = "2019",
abstract = "In this study we evaluate apoptosis time window of primary fibroblasts treated with cold atmospheric plasma (CAP), power range 0.4-1.4 W, for 30 sec, using γ-H2AX phosphorylation assay and flow cytometry. In contrast to irradiation where maximum of γ-H2AX foci appeared 30 min after irradiation and apoptosis 24 h later irrespective of radiation dose, treatment with CAP (power of 0.4 and 0.6) induces maximum of γ-H2AX foci 2 h after treatment. Apoptosis occurred in a power-dependent manner, with time shift of 2-3 h. Besides power-dependent time shift in apoptosis induction, apoptosis time window is the same and lasts for 2 h. © 2019, Indian Academy of Sciences.",
journal = "Current Science",
title = "Apoptosis time window induced by cold atmospheric plasma: Comparison with ionizing radiation",
volume = "116",
number = "7",
pages = "1229-1233",
doi = "10.18520/cs/v116/i7/1229-1233"
}

Joksić, G., Valenta-Šobot, A., Filipović Tričković, J. G., Maletić, D., Puač, N., Malović, G. N., Petrović, Z. Lj.,& Lazović, S.. (2019). Apoptosis time window induced by cold atmospheric plasma: Comparison with ionizing radiation. in Current Science, 116(7), 1229-1233.
https://doi.org/10.18520/cs/v116/i7/1229-1233

Joksić G, Valenta-Šobot A, Filipović Tričković JG, Maletić D, Puač N, Malović GN, Petrović ZL, Lazović S. Apoptosis time window induced by cold atmospheric plasma: Comparison with ionizing radiation. in Current Science. 2019;116(7):1229-1233.
doi:10.18520/cs/v116/i7/1229-1233 .

Joksić, Gordana, Valenta-Šobot, Ana, Filipović Tričković, Jelena G., Maletić, Dejan, Puač, Nevena, Malović, Gordana N., Petrović, Zoran Lj., Lazović, Saša, "Apoptosis time window induced by cold atmospheric plasma: Comparison with ionizing radiation" in Current Science, 116, no. 7 (2019):1229-1233,
https://doi.org/10.18520/cs/v116/i7/1229-1233 . .

TY  - CONF
AU  - Lazović, Saša
AU  - Maletić, Dimitrije
AU  - Leskovac, Andreja
AU  - Filipović, Jelena G.
AU  - Puač, N.
AU  - Malović, Gordana N.
AU  - Joksić, Gordana
AU  - Petrović, Z. Lj.
PY  - 2014
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10653
AB  - Atmospheric pressure plasma sources such as the plasma needle are being used for wound and chronic wound healing, cancer cell removal, stem cell manipulations, in dermatology, surgery, dentistry, etc. [1,2]. In our previous work we have optimized plasma needle parameters to efficiently sterilize E. Coli and S. Aureus in planktonic samples without causing damage to the peripheral blood mesenchymal stem cells used as a model for surrounding tissue [3]. Plasma treatments of human periodontal ligament mesenchymal stem cells have led to a promotion of osteogenic differentiation without affecting cell viability [4]. These results can be important for dentistry, especially for possible support or alternative to conventional regenerative procedures, such as guided tissue regeneration, the use of bone replacement grafts, and application of exogenous growth factors or proteins. Besides the promising short term effects of atmospheric non-thermal plasma on cells, it is necessary to study the long term effects, like for example DNA damage in order to prevent undesirable effects.
C3  - National Symposium on Plasma Science and Technology & International Conference on Plasma Science and Technology - PLASMA 2014 (29; 2014; Kotayyam, India)
T1  - Plasma Induced DNA Damage: Comparison with the Effects Of Ionizing Radiation And Establishing Effective Treatment Doses
SP  - 34
UR  - https://hdl.handle.net/21.15107/rcub_vinar_10653
ER  - 

@conference{
author = "Lazović, Saša and Maletić, Dimitrije and Leskovac, Andreja and Filipović, Jelena G. and Puač, N. and Malović, Gordana N. and Joksić, Gordana and Petrović, Z. Lj.",
year = "2014",
abstract = "Atmospheric pressure plasma sources such as the plasma needle are being used for wound and chronic wound healing, cancer cell removal, stem cell manipulations, in dermatology, surgery, dentistry, etc. [1,2]. In our previous work we have optimized plasma needle parameters to efficiently sterilize E. Coli and S. Aureus in planktonic samples without causing damage to the peripheral blood mesenchymal stem cells used as a model for surrounding tissue [3]. Plasma treatments of human periodontal ligament mesenchymal stem cells have led to a promotion of osteogenic differentiation without affecting cell viability [4]. These results can be important for dentistry, especially for possible support or alternative to conventional regenerative procedures, such as guided tissue regeneration, the use of bone replacement grafts, and application of exogenous growth factors or proteins. Besides the promising short term effects of atmospheric non-thermal plasma on cells, it is necessary to study the long term effects, like for example DNA damage in order to prevent undesirable effects.",
journal = "National Symposium on Plasma Science and Technology & International Conference on Plasma Science and Technology - PLASMA 2014 (29; 2014; Kotayyam, India)",
title = "Plasma Induced DNA Damage: Comparison with the Effects Of Ionizing Radiation And Establishing Effective Treatment Doses",
pages = "34",
url = "https://hdl.handle.net/21.15107/rcub_vinar_10653"
}

Lazović, S., Maletić, D., Leskovac, A., Filipović, J. G., Puač, N., Malović, G. N., Joksić, G.,& Petrović, Z. Lj.. (2014). Plasma Induced DNA Damage: Comparison with the Effects Of Ionizing Radiation And Establishing Effective Treatment Doses. in National Symposium on Plasma Science and Technology & International Conference on Plasma Science and Technology - PLASMA 2014 (29; 2014; Kotayyam, India), 34.
https://hdl.handle.net/21.15107/rcub_vinar_10653

Lazović S, Maletić D, Leskovac A, Filipović JG, Puač N, Malović GN, Joksić G, Petrović ZL. Plasma Induced DNA Damage: Comparison with the Effects Of Ionizing Radiation And Establishing Effective Treatment Doses. in National Symposium on Plasma Science and Technology & International Conference on Plasma Science and Technology - PLASMA 2014 (29; 2014; Kotayyam, India). 2014;:34.
https://hdl.handle.net/21.15107/rcub_vinar_10653 .

Lazović, Saša, Maletić, Dimitrije, Leskovac, Andreja, Filipović, Jelena G., Puač, N., Malović, Gordana N., Joksić, Gordana, Petrović, Z. Lj., "Plasma Induced DNA Damage: Comparison with the Effects Of Ionizing Radiation And Establishing Effective Treatment Doses" in National Symposium on Plasma Science and Technology & International Conference on Plasma Science and Technology - PLASMA 2014 (29; 2014; Kotayyam, India) (2014):34,
https://hdl.handle.net/21.15107/rcub_vinar_10653 .

TY  - JOUR
AU  - Lazovic, S.
AU  - Maletić, Dimitrije
AU  - Leskovac, Andreja
AU  - Filipović, Jelena G.
AU  - Puac, N.
AU  - Malović, Gordana N.
AU  - Joksić, Gordana
AU  - Petrović, Z. Lj.
PY  - 2014
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/154
AB  - We use human primary fibroblasts for comparing plasma and gamma rays induced DNA damage. In both cases, DNA strand breaks occur, but of fundamentally different nature. Unlike gamma exposure, contact with plasma predominantly leads to single strand breaks and base-damages, while double strand breaks are mainly consequence of the cell repair mechanisms. Different cell signaling mechanisms are detected confirming this (ataxia telangiectasia mutated - ATM and ataxia telangiectasia and Rad3 related - ATR, respectively). The effective plasma doses can be tuned to match the typical therapeutic doses of 2Gy. Tailoring the effective dose through plasma power and duration of the treatment enables safety precautions mainly by inducing apoptosis and consequently reduced frequency of micronuclei. (C) 2014 AIP Publishing LLC.
T2  - Applied Physics Letters
T1  - Plasma induced DNA damage: Comparison with the effects of ionizing radiation
VL  - 105
IS  - 12
DO  - 10.1063/1.4896626
ER  - 

@article{
author = "Lazovic, S. and Maletić, Dimitrije and Leskovac, Andreja and Filipović, Jelena G. and Puac, N. and Malović, Gordana N. and Joksić, Gordana and Petrović, Z. Lj.",
year = "2014",
abstract = "We use human primary fibroblasts for comparing plasma and gamma rays induced DNA damage. In both cases, DNA strand breaks occur, but of fundamentally different nature. Unlike gamma exposure, contact with plasma predominantly leads to single strand breaks and base-damages, while double strand breaks are mainly consequence of the cell repair mechanisms. Different cell signaling mechanisms are detected confirming this (ataxia telangiectasia mutated - ATM and ataxia telangiectasia and Rad3 related - ATR, respectively). The effective plasma doses can be tuned to match the typical therapeutic doses of 2Gy. Tailoring the effective dose through plasma power and duration of the treatment enables safety precautions mainly by inducing apoptosis and consequently reduced frequency of micronuclei. (C) 2014 AIP Publishing LLC.",
journal = "Applied Physics Letters",
title = "Plasma induced DNA damage: Comparison with the effects of ionizing radiation",
volume = "105",
number = "12",
doi = "10.1063/1.4896626"
}

Lazovic, S., Maletić, D., Leskovac, A., Filipović, J. G., Puac, N., Malović, G. N., Joksić, G.,& Petrović, Z. Lj.. (2014). Plasma induced DNA damage: Comparison with the effects of ionizing radiation. in Applied Physics Letters, 105(12).
https://doi.org/10.1063/1.4896626

Lazovic S, Maletić D, Leskovac A, Filipović JG, Puac N, Malović GN, Joksić G, Petrović ZL. Plasma induced DNA damage: Comparison with the effects of ionizing radiation. in Applied Physics Letters. 2014;105(12).
doi:10.1063/1.4896626 .

Lazovic, S., Maletić, Dimitrije, Leskovac, Andreja, Filipović, Jelena G., Puac, N., Malović, Gordana N., Joksić, Gordana, Petrović, Z. Lj., "Plasma induced DNA damage: Comparison with the effects of ionizing radiation" in Applied Physics Letters, 105, no. 12 (2014),
https://doi.org/10.1063/1.4896626 . .

TY  - JOUR
AU  - Radmilović-Rađenović, Marija
AU  - Petrovic, Z. Li.
AU  - Malović, Gordana N.
AU  - Maric, D.
PY  - 2006
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/6625
AB  - This paper compares the basic phenomenological model based on the Townsends theory and the detailed simulation of the gas breakdown in argon in uniform DC electric field. Calculations were carried out by using a one-dimensional particle-in-cell/Monte Carlo (PIC/MCC) code with three velocity components with a new secondary emission model. The simulation results clearly show how different models of the secondary electron emission affect the breakdown voltage. The fact that results of simulation are in a good agreement with the available experimental data merely means that phenomenological secondary electron yields were developed to fit the experiment. However, oversimplified models cannot predict all features of Townsend discharges and cannot be reconciled with binary collision data. One such example is the need to predict the DC volt-ampere characteristics in order to reveal the predominant physical processes by studying the j/p(2) scaling.
T2  - Czechoslovak Journal of Physics
T1  - Modelling of low-pressure gas breakdown in uniform DC electric field by PIC technique with realistic secondary electron emission
VL  - 56
SP  - B996
EP  - B1001
DO  - 10.1007/s10582-006-0316-y
ER  - 

@article{
author = "Radmilović-Rađenović, Marija and Petrovic, Z. Li. and Malović, Gordana N. and Maric, D.",
year = "2006",
abstract = "This paper compares the basic phenomenological model based on the Townsends theory and the detailed simulation of the gas breakdown in argon in uniform DC electric field. Calculations were carried out by using a one-dimensional particle-in-cell/Monte Carlo (PIC/MCC) code with three velocity components with a new secondary emission model. The simulation results clearly show how different models of the secondary electron emission affect the breakdown voltage. The fact that results of simulation are in a good agreement with the available experimental data merely means that phenomenological secondary electron yields were developed to fit the experiment. However, oversimplified models cannot predict all features of Townsend discharges and cannot be reconciled with binary collision data. One such example is the need to predict the DC volt-ampere characteristics in order to reveal the predominant physical processes by studying the j/p(2) scaling.",
journal = "Czechoslovak Journal of Physics",
title = "Modelling of low-pressure gas breakdown in uniform DC electric field by PIC technique with realistic secondary electron emission",
volume = "56",
pages = "B996-B1001",
doi = "10.1007/s10582-006-0316-y"
}

Radmilović-Rađenović, M., Petrovic, Z. Li., Malović, G. N.,& Maric, D.. (2006). Modelling of low-pressure gas breakdown in uniform DC electric field by PIC technique with realistic secondary electron emission. in Czechoslovak Journal of Physics, 56, B996-B1001.
https://doi.org/10.1007/s10582-006-0316-y

Radmilović-Rađenović M, Petrovic ZL, Malović GN, Maric D. Modelling of low-pressure gas breakdown in uniform DC electric field by PIC technique with realistic secondary electron emission. in Czechoslovak Journal of Physics. 2006;56:B996-B1001.
doi:10.1007/s10582-006-0316-y .

Radmilović-Rađenović, Marija, Petrovic, Z. Li., Malović, Gordana N., Maric, D., "Modelling of low-pressure gas breakdown in uniform DC electric field by PIC technique with realistic secondary electron emission" in Czechoslovak Journal of Physics, 56 (2006):B996-B1001,
https://doi.org/10.1007/s10582-006-0316-y . .