TY  - CONF
AU  - Vladisavljević, Goran T.
AU  - Henry, J. V.
AU  - Duncanson, Wynter J.
AU  - Shum, Ho C.
AU  - Weitz, David A.
PY  - 2012
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/6982
AB  - Monodisperse poly(dl-lactic acid) (PLA) particles with a diameter in the range from 12 to 100 mu m were fabricated in flow focusing glass capillary devices by evaporation of dichloromethane (DCM) from emulsions at room temperature. The dispersed phase was 5% (w/w) PLA in DCM containing a small amount of Nile red and the continuous phase was 5% (w/w) poly(vinyl alcohol) in reverse osmosis water. Particle diameter was 2.7 times smaller than the size of the emulsion droplet template indicating that the particle porosity was very low. SEM images revealed that the majority of particle pores are in the sub-micron region but in some instances these pores can reach 3 mu m in diameter. Droplet diameter was influenced by the flow rates of the two phases and the entry diameter of the collection capillary tube; droplet diameters decreased with increasing values of the flow rate ratio of the dispersed to continuous phase to reach constant minimum values at 40-60% orifice diameter. At flow rate ratios less than 5, jetting can occur, giving rise to large droplets formed by detachment from relatively long jets (similar to 10 times longer than droplet diameter).
C3  - Progress in Colloid and Polymer Science
T1  - Fabrication of Biodegradable Poly(Lactic Acid) Particles in Flow-Focusing Glass Capillary Devices
VL  - 139
SP  - 111
EP  - +
DO  - 10.1007/978-3-642-28974-3_19
ER  - 

@conference{
author = "Vladisavljević, Goran T. and Henry, J. V. and Duncanson, Wynter J. and Shum, Ho C. and Weitz, David A.",
year = "2012",
abstract = "Monodisperse poly(dl-lactic acid) (PLA) particles with a diameter in the range from 12 to 100 mu m were fabricated in flow focusing glass capillary devices by evaporation of dichloromethane (DCM) from emulsions at room temperature. The dispersed phase was 5% (w/w) PLA in DCM containing a small amount of Nile red and the continuous phase was 5% (w/w) poly(vinyl alcohol) in reverse osmosis water. Particle diameter was 2.7 times smaller than the size of the emulsion droplet template indicating that the particle porosity was very low. SEM images revealed that the majority of particle pores are in the sub-micron region but in some instances these pores can reach 3 mu m in diameter. Droplet diameter was influenced by the flow rates of the two phases and the entry diameter of the collection capillary tube; droplet diameters decreased with increasing values of the flow rate ratio of the dispersed to continuous phase to reach constant minimum values at 40-60% orifice diameter. At flow rate ratios less than 5, jetting can occur, giving rise to large droplets formed by detachment from relatively long jets (similar to 10 times longer than droplet diameter).",
journal = "Progress in Colloid and Polymer Science",
title = "Fabrication of Biodegradable Poly(Lactic Acid) Particles in Flow-Focusing Glass Capillary Devices",
volume = "139",
pages = "111-+",
doi = "10.1007/978-3-642-28974-3_19"
}

Vladisavljević, G. T., Henry, J. V., Duncanson, W. J., Shum, H. C.,& Weitz, D. A.. (2012). Fabrication of Biodegradable Poly(Lactic Acid) Particles in Flow-Focusing Glass Capillary Devices. in Progress in Colloid and Polymer Science, 139, 111-+.
https://doi.org/10.1007/978-3-642-28974-3_19

Vladisavljević GT, Henry JV, Duncanson WJ, Shum HC, Weitz DA. Fabrication of Biodegradable Poly(Lactic Acid) Particles in Flow-Focusing Glass Capillary Devices. in Progress in Colloid and Polymer Science. 2012;139:111-+.
doi:10.1007/978-3-642-28974-3_19 .

Vladisavljević, Goran T., Henry, J. V., Duncanson, Wynter J., Shum, Ho C., Weitz, David A., "Fabrication of Biodegradable Poly(Lactic Acid) Particles in Flow-Focusing Glass Capillary Devices" in Progress in Colloid and Polymer Science, 139 (2012):111-+,
https://doi.org/10.1007/978-3-642-28974-3_19 . .

TY  - JOUR
AU  - Vladisavljević, Goran T.
AU  - Duncanson, Wynter J.
AU  - Shum, Ho Cheung
AU  - Weitz, David A.
PY  - 2012
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/5039
AB  - Monodisperse poly(DL-lactic acid) (PLA) particles of diameters between 11 and 121 mu m were fabricated in flow focusing glass microcapillary devices by evaporation of dichloromethane (DCM) from emulsion droplets at room temperature. The dispersed phase was 5% (w/w) PLA in DCM containing 0.1-2 mM Nile Red and the continuous phase was 5% (w/w) poly(vinyl alcohol) in reverse osmosis water. Particle diameter was 2.7 times smaller than the diameter of the emulsion droplet template, indicating very low particle porosity. Monodisperse droplets have only been produced under dripping regime using a wide range of dispersed phase flow rates (0.002-7.2 cm(3).h(-1)), continuous phase flow rates (0.3-30 cm(3).h(-1)), and orifice diameters (50-237 mu m). In the dripping regime, the ratio of droplet diameter to orifice diameter was inversely proportional to the 0.39 power of the ratio of the continuous phase flow rate to dispersed phase flow rate. Highly uniform droplets with a coefficient of variation (CV) below 2% and a ratio of the droplet diameter to orifice diameter of 0.5-1 were obtained at flow rate ratios of 4-25. Under jetting regime, polydisperse droplets (CV GT 6%) were formed by detachment from relatively long jets (between 4 and 10 times longer than droplet diameter) and a ratio of the droplet size to orifice size of 2-5.
T2  - Langmuir
T1  - Emulsion Templating of Poly(lactic acid) Particles: Droplet Formation Behavior
VL  - 28
IS  - 36
SP  - 12948
EP  - 12954
DO  - 10.1021/la302092f
ER  - 

@article{
author = "Vladisavljević, Goran T. and Duncanson, Wynter J. and Shum, Ho Cheung and Weitz, David A.",
year = "2012",
abstract = "Monodisperse poly(DL-lactic acid) (PLA) particles of diameters between 11 and 121 mu m were fabricated in flow focusing glass microcapillary devices by evaporation of dichloromethane (DCM) from emulsion droplets at room temperature. The dispersed phase was 5% (w/w) PLA in DCM containing 0.1-2 mM Nile Red and the continuous phase was 5% (w/w) poly(vinyl alcohol) in reverse osmosis water. Particle diameter was 2.7 times smaller than the diameter of the emulsion droplet template, indicating very low particle porosity. Monodisperse droplets have only been produced under dripping regime using a wide range of dispersed phase flow rates (0.002-7.2 cm(3).h(-1)), continuous phase flow rates (0.3-30 cm(3).h(-1)), and orifice diameters (50-237 mu m). In the dripping regime, the ratio of droplet diameter to orifice diameter was inversely proportional to the 0.39 power of the ratio of the continuous phase flow rate to dispersed phase flow rate. Highly uniform droplets with a coefficient of variation (CV) below 2% and a ratio of the droplet diameter to orifice diameter of 0.5-1 were obtained at flow rate ratios of 4-25. Under jetting regime, polydisperse droplets (CV GT 6%) were formed by detachment from relatively long jets (between 4 and 10 times longer than droplet diameter) and a ratio of the droplet size to orifice size of 2-5.",
journal = "Langmuir",
title = "Emulsion Templating of Poly(lactic acid) Particles: Droplet Formation Behavior",
volume = "28",
number = "36",
pages = "12948-12954",
doi = "10.1021/la302092f"
}

Vladisavljević, G. T., Duncanson, W. J., Shum, H. C.,& Weitz, D. A.. (2012). Emulsion Templating of Poly(lactic acid) Particles: Droplet Formation Behavior. in Langmuir, 28(36), 12948-12954.
https://doi.org/10.1021/la302092f

Vladisavljević GT, Duncanson WJ, Shum HC, Weitz DA. Emulsion Templating of Poly(lactic acid) Particles: Droplet Formation Behavior. in Langmuir. 2012;28(36):12948-12954.
doi:10.1021/la302092f .

Vladisavljević, Goran T., Duncanson, Wynter J., Shum, Ho Cheung, Weitz, David A., "Emulsion Templating of Poly(lactic acid) Particles: Droplet Formation Behavior" in Langmuir, 28, no. 36 (2012):12948-12954,
https://doi.org/10.1021/la302092f . .