Obradović, Zorica

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  • Obradović, Zorica (15)
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Author's Bibliography

Optimization of radioprotective dose of Juglans nigra leaf extract using response surface methodology

Rajković, Katarina M.; Đurašević, Mirjana; Markićević, Milan; Milanović, Zorana; Vranješ-Đurić, Sanja; Janković, Drina; Stanković, Dragana; Obradović, Zorica

(2024)

TY  - JOUR
AU  - Rajković, Katarina M.
AU  - Đurašević, Mirjana
AU  - Markićević, Milan
AU  - Milanović, Zorana
AU  - Vranješ-Đurić, Sanja
AU  - Janković, Drina
AU  - Stanković, Dragana
AU  - Obradović, Zorica
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12239
AB  - J. nigra leaf contains mixture of various pharmacologically active compounds and it is assumed that they may have the potential radioprotective effect. The purpose of this work was to predict radioprotective doses by correlating changes in organ distribution of radiopharmaceuticals with extract dose levels and rat body weight using response surface methodology (RSM) based on a second-order polynomial equation. The extract was administered daily by oral gavage to rats at dose of 6.9, 10.3, or 13.7 mg kg−1 body weight (bw) day−1 for 10 days. On the eleventh day, 0.1 ml of the one radiopharmaceutical (Na99mTcO4, 99mTc-dimercaptosuccinic acid and 99mTc-tin colloid) was injected into the tail vein. The statistical parameters: the coefficient of determination (0.81–0.95), the coefficient of variation (3.05–11.1), the adequate precision (8.82–19.12) and the mean relative percentage deviation (± 2.3–8.2) were indicated the precision and reliability of RSM. Using RSM, the predicted daily dose of leaf extract ranging from 11.19 to 11.99 mg kg−1 bw may be considered as an optimal daily radiopotective dose for protection of organs from radiation in cases of planned radiation exposures.
T2  - Journal of Environmental Radioactivity
T1  - Optimization of radioprotective dose of Juglans nigra leaf extract using response surface methodology
VL  - 272
SP  - 107333
DO  - 10.1016/j.jenvrad.2023.107333
ER  - 
@article{
author = "Rajković, Katarina M. and Đurašević, Mirjana and Markićević, Milan and Milanović, Zorana and Vranješ-Đurić, Sanja and Janković, Drina and Stanković, Dragana and Obradović, Zorica",
year = "2024",
abstract = "J. nigra leaf contains mixture of various pharmacologically active compounds and it is assumed that they may have the potential radioprotective effect. The purpose of this work was to predict radioprotective doses by correlating changes in organ distribution of radiopharmaceuticals with extract dose levels and rat body weight using response surface methodology (RSM) based on a second-order polynomial equation. The extract was administered daily by oral gavage to rats at dose of 6.9, 10.3, or 13.7 mg kg−1 body weight (bw) day−1 for 10 days. On the eleventh day, 0.1 ml of the one radiopharmaceutical (Na99mTcO4, 99mTc-dimercaptosuccinic acid and 99mTc-tin colloid) was injected into the tail vein. The statistical parameters: the coefficient of determination (0.81–0.95), the coefficient of variation (3.05–11.1), the adequate precision (8.82–19.12) and the mean relative percentage deviation (± 2.3–8.2) were indicated the precision and reliability of RSM. Using RSM, the predicted daily dose of leaf extract ranging from 11.19 to 11.99 mg kg−1 bw may be considered as an optimal daily radiopotective dose for protection of organs from radiation in cases of planned radiation exposures.",
journal = "Journal of Environmental Radioactivity",
title = "Optimization of radioprotective dose of Juglans nigra leaf extract using response surface methodology",
volume = "272",
pages = "107333",
doi = "10.1016/j.jenvrad.2023.107333"
}
Rajković, K. M., Đurašević, M., Markićević, M., Milanović, Z., Vranješ-Đurić, S., Janković, D., Stanković, D.,& Obradović, Z.. (2024). Optimization of radioprotective dose of Juglans nigra leaf extract using response surface methodology. in Journal of Environmental Radioactivity, 272, 107333.
https://doi.org/10.1016/j.jenvrad.2023.107333
Rajković KM, Đurašević M, Markićević M, Milanović Z, Vranješ-Đurić S, Janković D, Stanković D, Obradović Z. Optimization of radioprotective dose of Juglans nigra leaf extract using response surface methodology. in Journal of Environmental Radioactivity. 2024;272:107333.
doi:10.1016/j.jenvrad.2023.107333 .
Rajković, Katarina M., Đurašević, Mirjana, Markićević, Milan, Milanović, Zorana, Vranješ-Đurić, Sanja, Janković, Drina, Stanković, Dragana, Obradović, Zorica, "Optimization of radioprotective dose of Juglans nigra leaf extract using response surface methodology" in Journal of Environmental Radioactivity, 272 (2024):107333,
https://doi.org/10.1016/j.jenvrad.2023.107333 . .

The prediction of radioprotective dose of a Juglansnigra L. leaf extracts in diagnostic irradiation using response surface methodology

Đurašević, Mirjana M.; Rajković, Katarina; Milanović, Zorana; Vranješ-Đurić, Sanja; Janković, Drina; Mirković, Marija D.; Obradović, Zorica

(Niš : RAD Centre, 2023)

TY  - CONF
AU  - Đurašević, Mirjana M.
AU  - Rajković, Katarina
AU  - Milanović, Zorana
AU  - Vranješ-Đurić, Sanja
AU  - Janković, Drina
AU  - Mirković, Marija D.
AU  - Obradović, Zorica
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12232
AB  - Juglansnigraleaf is a source of health-promoting biologically active compounds and used in traditional
medicine. Can we predict theradioprotective dose level of plant extracts based on modeling change
biodistribution of radiopharmaceuticals by response surface methodology (RSM)? The present study aimed
to the effects of J. nigra leaf extract oral intake on the biodistribution of 99mTc-radiopharmaceutical in
healthy rats and to formulate a mathematical model that will associate the changes in radioactivity in organ
with dose levels of extract and body mass of rats. The extract was administered daily by oral gavage to rats at
dose levels of 6.9, 10.3, or 13.7 mg kg-1 body weight (bw) day-1 for 10 days. On the eleventh day, 0.1 ml
(approximately 148 kBq) of the 99mTc-dimercaptosuccinic acid (DMSA) was injected into the tail vein. The
organs of interest were isolated and radioactivity in each organ was counted by a gamma counter with a NaI
(Tl) detector. After treatment of rats with the extract, there was a statistically significant decrease (p<0.05) in
the uptake of 99mTc-DMSA (%ID/organ) in the kidneys compared to controls.The RSM model based on the
second-order polynomial equation was apply to correlate changes in radioactivity in kidney with dose levels of
extract and body mass of rats.The statistical significance of RSM as well as independent variables and their
interactions were estimated by ANOVA (Analysis of variance). The F-value (265) and p-value (< 0,001)
demonstrated that the developed model has statistical significance at the confidence level of 95%. The R2
values (0.987) proved a good fit by the second-order polynomial equation, while relatively low values of the
CV (0.69) indicated the remarkable precision and reliability of the model. The low value of mean relative
percent deviation (0.4) between the experimental data and the predicted radioactivity of kidney obtained by
RSM showed that RSM was suitable for modeling the change biodistributionof radiopharmaceutical.
Modeling data provided evidence that the radioactivityof kidney statistically depended dose levels of extract
and statistically not depended of body mass of rats. RSM gave the minimum predicted value of radioactivity
of kidney 59%, which corresponded to minimum dose levelof 11.18 mg kg-1and minimum body massof 130 g.
RSM showed that extracts of J. nigraleaf kidney system protectionat doses higher than 11.18 mg kg-1. These
results suggest the potential use minimal dose level of J. nigraleaf extract as a radioprotector in cases of
planned radiation exposures.
PB  - Niš : RAD Centre
C3  - RAD 2023 : 11th International Conference on Radiation Natural Sciences, Medicine, Engineering, Technology and Ecology : Book of Abstracts
T1  - The prediction of radioprotective dose of a Juglansnigra L. leaf extracts in diagnostic irradiation using response surface methodology
SP  - 265
EP  - 265
DO  - 10.21175/rad.abstr.book.2023.41.1
ER  - 
@conference{
author = "Đurašević, Mirjana M. and Rajković, Katarina and Milanović, Zorana and Vranješ-Đurić, Sanja and Janković, Drina and Mirković, Marija D. and Obradović, Zorica",
year = "2023",
abstract = "Juglansnigraleaf is a source of health-promoting biologically active compounds and used in traditional
medicine. Can we predict theradioprotective dose level of plant extracts based on modeling change
biodistribution of radiopharmaceuticals by response surface methodology (RSM)? The present study aimed
to the effects of J. nigra leaf extract oral intake on the biodistribution of 99mTc-radiopharmaceutical in
healthy rats and to formulate a mathematical model that will associate the changes in radioactivity in organ
with dose levels of extract and body mass of rats. The extract was administered daily by oral gavage to rats at
dose levels of 6.9, 10.3, or 13.7 mg kg-1 body weight (bw) day-1 for 10 days. On the eleventh day, 0.1 ml
(approximately 148 kBq) of the 99mTc-dimercaptosuccinic acid (DMSA) was injected into the tail vein. The
organs of interest were isolated and radioactivity in each organ was counted by a gamma counter with a NaI
(Tl) detector. After treatment of rats with the extract, there was a statistically significant decrease (p<0.05) in
the uptake of 99mTc-DMSA (%ID/organ) in the kidneys compared to controls.The RSM model based on the
second-order polynomial equation was apply to correlate changes in radioactivity in kidney with dose levels of
extract and body mass of rats.The statistical significance of RSM as well as independent variables and their
interactions were estimated by ANOVA (Analysis of variance). The F-value (265) and p-value (< 0,001)
demonstrated that the developed model has statistical significance at the confidence level of 95%. The R2
values (0.987) proved a good fit by the second-order polynomial equation, while relatively low values of the
CV (0.69) indicated the remarkable precision and reliability of the model. The low value of mean relative
percent deviation (0.4) between the experimental data and the predicted radioactivity of kidney obtained by
RSM showed that RSM was suitable for modeling the change biodistributionof radiopharmaceutical.
Modeling data provided evidence that the radioactivityof kidney statistically depended dose levels of extract
and statistically not depended of body mass of rats. RSM gave the minimum predicted value of radioactivity
of kidney 59%, which corresponded to minimum dose levelof 11.18 mg kg-1and minimum body massof 130 g.
RSM showed that extracts of J. nigraleaf kidney system protectionat doses higher than 11.18 mg kg-1. These
results suggest the potential use minimal dose level of J. nigraleaf extract as a radioprotector in cases of
planned radiation exposures.",
publisher = "Niš : RAD Centre",
journal = "RAD 2023 : 11th International Conference on Radiation Natural Sciences, Medicine, Engineering, Technology and Ecology : Book of Abstracts",
title = "The prediction of radioprotective dose of a Juglansnigra L. leaf extracts in diagnostic irradiation using response surface methodology",
pages = "265-265",
doi = "10.21175/rad.abstr.book.2023.41.1"
}
Đurašević, M. M., Rajković, K., Milanović, Z., Vranješ-Đurić, S., Janković, D., Mirković, M. D.,& Obradović, Z.. (2023). The prediction of radioprotective dose of a Juglansnigra L. leaf extracts in diagnostic irradiation using response surface methodology. in RAD 2023 : 11th International Conference on Radiation Natural Sciences, Medicine, Engineering, Technology and Ecology : Book of Abstracts
Niš : RAD Centre., 265-265.
https://doi.org/10.21175/rad.abstr.book.2023.41.1
Đurašević MM, Rajković K, Milanović Z, Vranješ-Đurić S, Janković D, Mirković MD, Obradović Z. The prediction of radioprotective dose of a Juglansnigra L. leaf extracts in diagnostic irradiation using response surface methodology. in RAD 2023 : 11th International Conference on Radiation Natural Sciences, Medicine, Engineering, Technology and Ecology : Book of Abstracts. 2023;:265-265.
doi:10.21175/rad.abstr.book.2023.41.1 .
Đurašević, Mirjana M., Rajković, Katarina, Milanović, Zorana, Vranješ-Đurić, Sanja, Janković, Drina, Mirković, Marija D., Obradović, Zorica, "The prediction of radioprotective dose of a Juglansnigra L. leaf extracts in diagnostic irradiation using response surface methodology" in RAD 2023 : 11th International Conference on Radiation Natural Sciences, Medicine, Engineering, Technology and Ecology : Book of Abstracts (2023):265-265,
https://doi.org/10.21175/rad.abstr.book.2023.41.1 . .

Radiološka analiza nekih vrsta lekovitog bilja sa područja Gučeva i procena godišnje efektivne doze usled ingestije

Đurašević, Mirjana M.; Čeliković, Igor T.; Samolov, Aleksandra; Milanović, Tamara; Obradović, Zorica; Kandić, Irina; Kandić, Aleksandar

(Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", 2023)

TY  - CONF
AU  - Đurašević, Mirjana M.
AU  - Čeliković, Igor T.
AU  - Samolov, Aleksandra
AU  - Milanović, Tamara
AU  - Obradović, Zorica
AU  - Kandić, Irina
AU  - Kandić, Aleksandar
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/11944
AB  - U bogatoj flori Srbije uspeva veliki broj vrsta lekovitog bilja čiji se sastojci koriste u farmaceutskoj industriji i medicini, kako zvaničnoj tako i narodnoj. Pored toga lekovito bilje se u velikoj meri koristi u svakodnevnoj upotrebi kao neka vrsta napitka. Prirodni radionuklidi (radionuklidi uranovog i torijumovog niza kao i K-40) sastavni su deo naše životne sredine, a kao posledicu nuklearnih akcidenata imamo i prisustvo antropogenih radionuklida, pre svega Cs-137. Masovna upotreba lekovitog bilja predstavlja radijaciono opterećenje za široku populaciju, pa je zbog toga neophodan redovan monitoring. U ovom radu analizirano je 9 vrsta lekovitog bilja sa područja Gučeva (Zapadna Srbija). Specifične aktivnosti prirodnih radionuklida Pb-210 i K-40, kao i Cs-137 određene su merenjem svih uzoraka na poluprovodničkom HPGe spektrometru. Izračunate su godišnje efektivne doze usled ingestije za svaki izmereni radionuklid, i za dve starosne kategorije (uzrast od jedne godine i odrasla osoba). Svi proračuni su zasnovani na pretpostavci da se dnevno pije 200 ml čaja priprepremljenog korišćenjem određene lekovite biljake. Dobijene vrednosti za efektivnu dozu ingestije upućuju na zaključak da svakodnevna upotreba čajeva od lekovitih biljaka sa analiziranog područja ne predstavlja značajan radiološki rizik po zdravlje odrasle osobe, ali je neophodan oprez i obazrivost kada su u pitanju deca.
AB  - In the rich flora of Serbia, there are a large number of medicinal plants types used in the pharmaceutical industry and medicine. There is also a large percentage of daily use of herbal teas as some kind of beverages. Natural radionuclides (radionuclides of the uranium and thorium series as well as K-40) are an integral part of our environment, and as a consequence of nuclear accidents we also have the presence of anthropogenic radionuclides, primarily Cs-137. The significant use of medicinal plants represent a radiological burden for the general population, so the regular monitoring is needed. In this work, 9 types of medicinal plants from the area of Gučevo (Western Serbia) were analysed. The specific activities of natural radionuclides 210-Pb i 40-K as well as Cs-137 were determined using a semiconductor HPGe spectrometer. Annual effective dose due to ingestion were calculated for each measured radionuclide, and for two age categories (one year old and adult). All calculations are based on the assumption daily consumption of 200 ml of herbal tea. The obtained values for the annual effective dose due to ingestion point to the conclusion that the daily use of medicinal plant teas from the analyzed area does not represent a significant radiological risk for the health of adults, but caution and prudence are necessary when it is about children.
PB  - Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"
PB  - Društvo za zaštitu od zračenja Srbije i Crne Gore
C3  - 32. simpozijum DZZSCG : zbornik radova
T1  - Radiološka analiza nekih vrsta lekovitog bilja sa područja Gučeva i procena godišnje efektivne doze usled ingestije
T1  - Radiological Analysis of Some Types of Medicinal Plants From the Gučevo Area and Estimation of Annual Effective Dose Due To Ingestation
SP  - 42
EP  - 48
UR  - https://hdl.handle.net/21.15107/rcub_vinar_11944
ER  - 
@conference{
author = "Đurašević, Mirjana M. and Čeliković, Igor T. and Samolov, Aleksandra and Milanović, Tamara and Obradović, Zorica and Kandić, Irina and Kandić, Aleksandar",
year = "2023",
abstract = "U bogatoj flori Srbije uspeva veliki broj vrsta lekovitog bilja čiji se sastojci koriste u farmaceutskoj industriji i medicini, kako zvaničnoj tako i narodnoj. Pored toga lekovito bilje se u velikoj meri koristi u svakodnevnoj upotrebi kao neka vrsta napitka. Prirodni radionuklidi (radionuklidi uranovog i torijumovog niza kao i K-40) sastavni su deo naše životne sredine, a kao posledicu nuklearnih akcidenata imamo i prisustvo antropogenih radionuklida, pre svega Cs-137. Masovna upotreba lekovitog bilja predstavlja radijaciono opterećenje za široku populaciju, pa je zbog toga neophodan redovan monitoring. U ovom radu analizirano je 9 vrsta lekovitog bilja sa područja Gučeva (Zapadna Srbija). Specifične aktivnosti prirodnih radionuklida Pb-210 i K-40, kao i Cs-137 određene su merenjem svih uzoraka na poluprovodničkom HPGe spektrometru. Izračunate su godišnje efektivne doze usled ingestije za svaki izmereni radionuklid, i za dve starosne kategorije (uzrast od jedne godine i odrasla osoba). Svi proračuni su zasnovani na pretpostavci da se dnevno pije 200 ml čaja priprepremljenog korišćenjem određene lekovite biljake. Dobijene vrednosti za efektivnu dozu ingestije upućuju na zaključak da svakodnevna upotreba čajeva od lekovitih biljaka sa analiziranog područja ne predstavlja značajan radiološki rizik po zdravlje odrasle osobe, ali je neophodan oprez i obazrivost kada su u pitanju deca., In the rich flora of Serbia, there are a large number of medicinal plants types used in the pharmaceutical industry and medicine. There is also a large percentage of daily use of herbal teas as some kind of beverages. Natural radionuclides (radionuclides of the uranium and thorium series as well as K-40) are an integral part of our environment, and as a consequence of nuclear accidents we also have the presence of anthropogenic radionuclides, primarily Cs-137. The significant use of medicinal plants represent a radiological burden for the general population, so the regular monitoring is needed. In this work, 9 types of medicinal plants from the area of Gučevo (Western Serbia) were analysed. The specific activities of natural radionuclides 210-Pb i 40-K as well as Cs-137 were determined using a semiconductor HPGe spectrometer. Annual effective dose due to ingestion were calculated for each measured radionuclide, and for two age categories (one year old and adult). All calculations are based on the assumption daily consumption of 200 ml of herbal tea. The obtained values for the annual effective dose due to ingestion point to the conclusion that the daily use of medicinal plant teas from the analyzed area does not represent a significant radiological risk for the health of adults, but caution and prudence are necessary when it is about children.",
publisher = "Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", Društvo za zaštitu od zračenja Srbije i Crne Gore",
journal = "32. simpozijum DZZSCG : zbornik radova",
title = "Radiološka analiza nekih vrsta lekovitog bilja sa područja Gučeva i procena godišnje efektivne doze usled ingestije, Radiological Analysis of Some Types of Medicinal Plants From the Gučevo Area and Estimation of Annual Effective Dose Due To Ingestation",
pages = "42-48",
url = "https://hdl.handle.net/21.15107/rcub_vinar_11944"
}
Đurašević, M. M., Čeliković, I. T., Samolov, A., Milanović, T., Obradović, Z., Kandić, I.,& Kandić, A.. (2023). Radiološka analiza nekih vrsta lekovitog bilja sa područja Gučeva i procena godišnje efektivne doze usled ingestije. in 32. simpozijum DZZSCG : zbornik radova
Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"., 42-48.
https://hdl.handle.net/21.15107/rcub_vinar_11944
Đurašević MM, Čeliković IT, Samolov A, Milanović T, Obradović Z, Kandić I, Kandić A. Radiološka analiza nekih vrsta lekovitog bilja sa područja Gučeva i procena godišnje efektivne doze usled ingestije. in 32. simpozijum DZZSCG : zbornik radova. 2023;:42-48.
https://hdl.handle.net/21.15107/rcub_vinar_11944 .
Đurašević, Mirjana M., Čeliković, Igor T., Samolov, Aleksandra, Milanović, Tamara, Obradović, Zorica, Kandić, Irina, Kandić, Aleksandar, "Radiološka analiza nekih vrsta lekovitog bilja sa područja Gučeva i procena godišnje efektivne doze usled ingestije" in 32. simpozijum DZZSCG : zbornik radova (2023):42-48,
https://hdl.handle.net/21.15107/rcub_vinar_11944 .

Novi pristup u konstrukciji zaštite u brahiterapiji - brahiterapijska komora

Stanković, Jovan; Mirkov, Zoran; Dabić-Stanković, Kata; Obradović, Zorica; Rajković, Katarina

(Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", 2023)

TY  - CONF
AU  - Stanković, Jovan
AU  - Mirkov, Zoran
AU  - Dabić-Stanković, Kata
AU  - Obradović, Zorica
AU  - Rajković, Katarina
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12183
AB  - Brahiterapijski uređaji sa izvorima velike aktivnosti (> 370 GBq) postavljaju se u posebne zaštitne bunkere, debljine zaštitnog betonskog zida oko 70 cm, što zahteva opsežnije građevinsko-tehničke radove i povećava cenu izrade (preko 100.000 Eura). Da bi se prevazišao problem ograničenog prostora unutar odeljenja brahiterapije, predlažemo izradu „brahiterapijske komore“ koja bi bila smeštena u aplikacionoj sali minimalne površine 30 m2. Komandni pult brahiterapijskog uređaja bi se nalazilo u parapetom/paravanom odvojenom delu sale. Brahiterapijska komora, pojedinačnih dimenzija (V x Š) oko 2 m, u obliku ćiričnog slova P (П), izrađuje se od olovnih ploča debljine 5 cm. Sa jedne strane komore (ulaz za pacijenta) navlačiće se pokretni/motorizovani paravan (debljine zida: 5 cm; dimenzija V x Š oko 2,3 m). U toku zračenja pacijent i uređaj se nalaze u komori. Cena izrade ove brahiterapijske komore sa pripadajućim elementima ne bi prelazila cenu izrade klasičnog brahiterapijskog bunkera.
AB  - Brachytherapy units with high activity sources (> 370 GBq) are placed in special protective treatment rooms, with concrete wall thickness of about 70 cm, which requires more extensive construction and technical works that increases the cost of production (over 100.000 Euros). In order to overcome the problem of limited space within the brachytherapy department, we propose construction of a "brachytherapy chamber" that would be located in the application teatre with a minimum area of 30 sqm. The control unit would be located in a separated part of the treatment room. The brachytherapy chamber, with an individual dimensions (H x W) of about 2 m, in the shape of the Cyrillic letter P (П), is made of lead plates 5 cm thick. On one side of the chamber (patient entrance) a movable/motorized screen (wall thickness: 5 cm; dimensions HxW each approx. 2.3 m) will be constructed. During radiation, the patient and theunit are in the chamber. The construction cost of this brachytherapy chamber with associated elements would not exceed the cost of making a classic brachytherapy treatment room.
PB  - Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"
PB  - Društvo za zaštitu od zračenja Srbije i Crne Gore
C3  - 32. simpozijum DZZSCG : zbornik radova
T1  - Novi pristup u konstrukciji zaštite u brahiterapiji - brahiterapijska komora
T1  - A New Approach in the Construction of Protection in Brachytherapy – Brachytherapy Chamber
SP  - 313
EP  - 320
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12183
ER  - 
@conference{
author = "Stanković, Jovan and Mirkov, Zoran and Dabić-Stanković, Kata and Obradović, Zorica and Rajković, Katarina",
year = "2023",
abstract = "Brahiterapijski uređaji sa izvorima velike aktivnosti (> 370 GBq) postavljaju se u posebne zaštitne bunkere, debljine zaštitnog betonskog zida oko 70 cm, što zahteva opsežnije građevinsko-tehničke radove i povećava cenu izrade (preko 100.000 Eura). Da bi se prevazišao problem ograničenog prostora unutar odeljenja brahiterapije, predlažemo izradu „brahiterapijske komore“ koja bi bila smeštena u aplikacionoj sali minimalne površine 30 m2. Komandni pult brahiterapijskog uređaja bi se nalazilo u parapetom/paravanom odvojenom delu sale. Brahiterapijska komora, pojedinačnih dimenzija (V x Š) oko 2 m, u obliku ćiričnog slova P (П), izrađuje se od olovnih ploča debljine 5 cm. Sa jedne strane komore (ulaz za pacijenta) navlačiće se pokretni/motorizovani paravan (debljine zida: 5 cm; dimenzija V x Š oko 2,3 m). U toku zračenja pacijent i uređaj se nalaze u komori. Cena izrade ove brahiterapijske komore sa pripadajućim elementima ne bi prelazila cenu izrade klasičnog brahiterapijskog bunkera., Brachytherapy units with high activity sources (> 370 GBq) are placed in special protective treatment rooms, with concrete wall thickness of about 70 cm, which requires more extensive construction and technical works that increases the cost of production (over 100.000 Euros). In order to overcome the problem of limited space within the brachytherapy department, we propose construction of a "brachytherapy chamber" that would be located in the application teatre with a minimum area of 30 sqm. The control unit would be located in a separated part of the treatment room. The brachytherapy chamber, with an individual dimensions (H x W) of about 2 m, in the shape of the Cyrillic letter P (П), is made of lead plates 5 cm thick. On one side of the chamber (patient entrance) a movable/motorized screen (wall thickness: 5 cm; dimensions HxW each approx. 2.3 m) will be constructed. During radiation, the patient and theunit are in the chamber. The construction cost of this brachytherapy chamber with associated elements would not exceed the cost of making a classic brachytherapy treatment room.",
publisher = "Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", Društvo za zaštitu od zračenja Srbije i Crne Gore",
journal = "32. simpozijum DZZSCG : zbornik radova",
title = "Novi pristup u konstrukciji zaštite u brahiterapiji - brahiterapijska komora, A New Approach in the Construction of Protection in Brachytherapy – Brachytherapy Chamber",
pages = "313-320",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12183"
}
Stanković, J., Mirkov, Z., Dabić-Stanković, K., Obradović, Z.,& Rajković, K.. (2023). Novi pristup u konstrukciji zaštite u brahiterapiji - brahiterapijska komora. in 32. simpozijum DZZSCG : zbornik radova
Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"., 313-320.
https://hdl.handle.net/21.15107/rcub_vinar_12183
Stanković J, Mirkov Z, Dabić-Stanković K, Obradović Z, Rajković K. Novi pristup u konstrukciji zaštite u brahiterapiji - brahiterapijska komora. in 32. simpozijum DZZSCG : zbornik radova. 2023;:313-320.
https://hdl.handle.net/21.15107/rcub_vinar_12183 .
Stanković, Jovan, Mirkov, Zoran, Dabić-Stanković, Kata, Obradović, Zorica, Rajković, Katarina, "Novi pristup u konstrukciji zaštite u brahiterapiji - brahiterapijska komora" in 32. simpozijum DZZSCG : zbornik radova (2023):313-320,
https://hdl.handle.net/21.15107/rcub_vinar_12183 .

Eksperimentalni model za procenu mogućeg radioprotektivnog efekta biljnog ekstrakta

Rajković, Katarina M.; Đurašević, Mirjana; Obradović, Zorica; Milanović, Zorana; Vukadinović, Aleksandar; Perić, Marko; Stanković, Dragana; Janković, Drina

(Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", 2023)

TY  - CONF
AU  - Rajković, Katarina M.
AU  - Đurašević, Mirjana
AU  - Obradović, Zorica
AU  - Milanović, Zorana
AU  - Vukadinović, Aleksandar
AU  - Perić, Marko
AU  - Stanković, Dragana
AU  - Janković, Drina
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12184
AB  - Tc-99m-radiofarmaceutici se koriste u različitim dijagnostičkim procedurama u nuklearnoj medicini. Da bi se minimizirali štetni efekti jonizujućeg zračenja na zdrava tkiva, intenzivno se istražuju radioprotektivne osobine biljnih ekstrakata. Ljuska ploda crnog oraha sadrži mešavinu različitih farmakološki aktivnih jedinjenja kojа imaju antioksidativno dejstvo i za koje se pretpostavlja da mogu imati i potencijalno radioprotektivno dejstvo. U tom kontekstu, cilj rada je bio da se proceni radioprotektivni efekat ekstrakta ljuske ploda crnog oraha. U ovoj studiji primenjen je eksperimentalni model koji se zasnivao na proceni uticaja ekstrakta na biodistribuciju Tc-99m-radiofarmaceutika po organima eksperimentalnih životinja (pacovi). Ekstrakt ljuske crnog oraha doveo je do smanjenognakupljanja Tc-99m-radiofarmaceutika u pojedinim organimapacova. Rezultati dobijeni na osnovu eksperimentalnog modela sugerišu moguću upotrebu ekstrakta ljuske ploda crnog oraha kao radioprotektivnog sredstva u slučajevima planiranog izlaganja jonizujućem zračenju u nuklearnoj medicini.
AB  - Tc-99m-radiopharmaceuticals are used in various diagnostic procedures in nuclear medicine. In order to minimize the harmful effects of ionizing radiation on healthy tissues, the radioprotective properties of plant extracts are intensively researched. J. nigra husk contains a mixture of various pharmacologically active compounds that have an antioxidant effect and which are assumed to have a potential radioprotective effect. In this context, the aim of the work was to evaluate the radioprotective effect of black walnut husk extract. In this study, an experimental model was applied, which was based on the assessment of the effect of the extract on the biodistribution of Tc-99m-radiopharmaceuticals in the organs of experimental animals (rats). Black walnut husk extract led to a decrease in the accumulation of Tc-99m-radiopharmaceutical in certain organs of rats. The results obtained on the basis of the experimental model suggest that it is possible to use black walnut husk extract as a radioprotective agent in cases of planned exposure to ionizing radiation in diagnosticsnuclear medicine.
PB  - Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"
PB  - Društvo za zaštitu od zračenja Srbije i Crne Gore
C3  - 32. simpozijum DZZSCG : zbornik radova
T1  - Eksperimentalni model za procenu mogućeg radioprotektivnog efekta biljnog ekstrakta
T1  - Experimental Model for Assessing the Possible Radioprotective Effect of Plant Extract
SP  - 321
EP  - 327
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12184
ER  - 
@conference{
author = "Rajković, Katarina M. and Đurašević, Mirjana and Obradović, Zorica and Milanović, Zorana and Vukadinović, Aleksandar and Perić, Marko and Stanković, Dragana and Janković, Drina",
year = "2023",
abstract = "Tc-99m-radiofarmaceutici se koriste u različitim dijagnostičkim procedurama u nuklearnoj medicini. Da bi se minimizirali štetni efekti jonizujućeg zračenja na zdrava tkiva, intenzivno se istražuju radioprotektivne osobine biljnih ekstrakata. Ljuska ploda crnog oraha sadrži mešavinu različitih farmakološki aktivnih jedinjenja kojа imaju antioksidativno dejstvo i za koje se pretpostavlja da mogu imati i potencijalno radioprotektivno dejstvo. U tom kontekstu, cilj rada je bio da se proceni radioprotektivni efekat ekstrakta ljuske ploda crnog oraha. U ovoj studiji primenjen je eksperimentalni model koji se zasnivao na proceni uticaja ekstrakta na biodistribuciju Tc-99m-radiofarmaceutika po organima eksperimentalnih životinja (pacovi). Ekstrakt ljuske crnog oraha doveo je do smanjenognakupljanja Tc-99m-radiofarmaceutika u pojedinim organimapacova. Rezultati dobijeni na osnovu eksperimentalnog modela sugerišu moguću upotrebu ekstrakta ljuske ploda crnog oraha kao radioprotektivnog sredstva u slučajevima planiranog izlaganja jonizujućem zračenju u nuklearnoj medicini., Tc-99m-radiopharmaceuticals are used in various diagnostic procedures in nuclear medicine. In order to minimize the harmful effects of ionizing radiation on healthy tissues, the radioprotective properties of plant extracts are intensively researched. J. nigra husk contains a mixture of various pharmacologically active compounds that have an antioxidant effect and which are assumed to have a potential radioprotective effect. In this context, the aim of the work was to evaluate the radioprotective effect of black walnut husk extract. In this study, an experimental model was applied, which was based on the assessment of the effect of the extract on the biodistribution of Tc-99m-radiopharmaceuticals in the organs of experimental animals (rats). Black walnut husk extract led to a decrease in the accumulation of Tc-99m-radiopharmaceutical in certain organs of rats. The results obtained on the basis of the experimental model suggest that it is possible to use black walnut husk extract as a radioprotective agent in cases of planned exposure to ionizing radiation in diagnosticsnuclear medicine.",
publisher = "Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča", Društvo za zaštitu od zračenja Srbije i Crne Gore",
journal = "32. simpozijum DZZSCG : zbornik radova",
title = "Eksperimentalni model za procenu mogućeg radioprotektivnog efekta biljnog ekstrakta, Experimental Model for Assessing the Possible Radioprotective Effect of Plant Extract",
pages = "321-327",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12184"
}
Rajković, K. M., Đurašević, M., Obradović, Z., Milanović, Z., Vukadinović, A., Perić, M., Stanković, D.,& Janković, D.. (2023). Eksperimentalni model za procenu mogućeg radioprotektivnog efekta biljnog ekstrakta. in 32. simpozijum DZZSCG : zbornik radova
Beograd : Univerzitet u Beogradu, Institut za nuklearne nauke "Vinča"., 321-327.
https://hdl.handle.net/21.15107/rcub_vinar_12184
Rajković KM, Đurašević M, Obradović Z, Milanović Z, Vukadinović A, Perić M, Stanković D, Janković D. Eksperimentalni model za procenu mogućeg radioprotektivnog efekta biljnog ekstrakta. in 32. simpozijum DZZSCG : zbornik radova. 2023;:321-327.
https://hdl.handle.net/21.15107/rcub_vinar_12184 .
Rajković, Katarina M., Đurašević, Mirjana, Obradović, Zorica, Milanović, Zorana, Vukadinović, Aleksandar, Perić, Marko, Stanković, Dragana, Janković, Drina, "Eksperimentalni model za procenu mogućeg radioprotektivnog efekta biljnog ekstrakta" in 32. simpozijum DZZSCG : zbornik radova (2023):321-327,
https://hdl.handle.net/21.15107/rcub_vinar_12184 .

A comparison of alpha-particle and gamma-ray spectrometry methods for determination of 235U, 238U and 226Ra activity concentration in samples of coal, slag and fly-ash

Vukanac, Ivana; Šešlak, Bojan Ž.; Kandić, Aleksandar; Čeliković, Igor T.; Mladenović-Nikolić, Nataša; Milanović, Tamara J.; Obradović, Zorica; Đurašević, Mirjana M.

(2022)

TY  - JOUR
AU  - Vukanac, Ivana
AU  - Šešlak, Bojan Ž.
AU  - Kandić, Aleksandar
AU  - Čeliković, Igor T.
AU  - Mladenović-Nikolić, Nataša
AU  - Milanović, Tamara J.
AU  - Obradović, Zorica
AU  - Đurašević, Mirjana M.
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10096
AB  - In order to compare alpha-particle and gamma-ray spectrometry, the activity concentrations of 235U, 238U and 226Ra in samples of coal, slag and fly-ash from the thermal power plant “Nikola Tesla A”, Serbia, were determined by these two methods. Methods were compared and discussed from the point of view of its precision, difficulty to apply and complexity. Gamma-ray spectrometry was performed with HPGe (High Purity Germanium) spectrometer, while alpha activity was measured by PIPS (Passivated Implanted Planar Silicon) detector. For the alpha-particle spectrometry, the chemical procedures applied were chromatographic resin extraction for uranium isotopes and micro-coprecipitation for 226Ra. Thin alpha sources were prepared by electrodeposition and filtration through polypropylene membrane filter for uranium determination, while filtration technique was performed for radium sources. For the evaluation of the statistical difference between individual measurement results obtained by application of two methods Z - test was used. In order to evaluate the difference between two methods used, paired samples t-test and F-test were applied. Results show that there is no statistical difference between two methods used and that gamma-ray spectrometry is a valid alternative to time consuming alpha spectrometry.
T2  - Radiation Physics and Chemistry
T1  - A comparison of alpha-particle and gamma-ray spectrometry methods for determination of 235U, 238U and 226Ra activity concentration in samples of coal, slag and fly-ash
VL  - 193
SP  - 109933
DO  - 10.1016/j.radphyschem.2021.109933
ER  - 
@article{
author = "Vukanac, Ivana and Šešlak, Bojan Ž. and Kandić, Aleksandar and Čeliković, Igor T. and Mladenović-Nikolić, Nataša and Milanović, Tamara J. and Obradović, Zorica and Đurašević, Mirjana M.",
year = "2022",
abstract = "In order to compare alpha-particle and gamma-ray spectrometry, the activity concentrations of 235U, 238U and 226Ra in samples of coal, slag and fly-ash from the thermal power plant “Nikola Tesla A”, Serbia, were determined by these two methods. Methods were compared and discussed from the point of view of its precision, difficulty to apply and complexity. Gamma-ray spectrometry was performed with HPGe (High Purity Germanium) spectrometer, while alpha activity was measured by PIPS (Passivated Implanted Planar Silicon) detector. For the alpha-particle spectrometry, the chemical procedures applied were chromatographic resin extraction for uranium isotopes and micro-coprecipitation for 226Ra. Thin alpha sources were prepared by electrodeposition and filtration through polypropylene membrane filter for uranium determination, while filtration technique was performed for radium sources. For the evaluation of the statistical difference between individual measurement results obtained by application of two methods Z - test was used. In order to evaluate the difference between two methods used, paired samples t-test and F-test were applied. Results show that there is no statistical difference between two methods used and that gamma-ray spectrometry is a valid alternative to time consuming alpha spectrometry.",
journal = "Radiation Physics and Chemistry",
title = "A comparison of alpha-particle and gamma-ray spectrometry methods for determination of 235U, 238U and 226Ra activity concentration in samples of coal, slag and fly-ash",
volume = "193",
pages = "109933",
doi = "10.1016/j.radphyschem.2021.109933"
}
Vukanac, I., Šešlak, B. Ž., Kandić, A., Čeliković, I. T., Mladenović-Nikolić, N., Milanović, T. J., Obradović, Z.,& Đurašević, M. M.. (2022). A comparison of alpha-particle and gamma-ray spectrometry methods for determination of 235U, 238U and 226Ra activity concentration in samples of coal, slag and fly-ash. in Radiation Physics and Chemistry, 193, 109933.
https://doi.org/10.1016/j.radphyschem.2021.109933
Vukanac I, Šešlak BŽ, Kandić A, Čeliković IT, Mladenović-Nikolić N, Milanović TJ, Obradović Z, Đurašević MM. A comparison of alpha-particle and gamma-ray spectrometry methods for determination of 235U, 238U and 226Ra activity concentration in samples of coal, slag and fly-ash. in Radiation Physics and Chemistry. 2022;193:109933.
doi:10.1016/j.radphyschem.2021.109933 .
Vukanac, Ivana, Šešlak, Bojan Ž., Kandić, Aleksandar, Čeliković, Igor T., Mladenović-Nikolić, Nataša, Milanović, Tamara J., Obradović, Zorica, Đurašević, Mirjana M., "A comparison of alpha-particle and gamma-ray spectrometry methods for determination of 235U, 238U and 226Ra activity concentration in samples of coal, slag and fly-ash" in Radiation Physics and Chemistry, 193 (2022):109933,
https://doi.org/10.1016/j.radphyschem.2021.109933 . .
12
5

Determination of radionuclide concentrations in soil and black walnut leaves and fruit using gamma-ray spectrometry

Đurašević, Mirjana M.; Kandić, Aleksandar; Čeliković, Igor T.; Rajković, Katarina; Kandić, Irina; Obradović, Zorica

(RAD Centre, Niš, Serbia, 2022)

TY  - CONF
AU  - Đurašević, Mirjana M.
AU  - Kandić, Aleksandar
AU  - Čeliković, Igor T.
AU  - Rajković, Katarina
AU  - Kandić, Irina
AU  - Obradović, Zorica
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/11107
AB  - This study showed that 137Cs concentrations in black walnut leaf and fruit, as well as in tinctures were below the detection limits. Concentrations of other radionuclides are lower than their concentrations in the soil, except for concentration of 40K in black walnut fruit, which objectively have more potassium due to the structure of the fruit. It indicates that the consumption of leaf and nut tinctureis absolutely safe, especially in relation to artificial radionuclides.
PB  - RAD Centre, Niš, Serbia
C3  - RAD 2022 : 10th Jubilee International Conference on Radiation in Various Fields of Research : book of abstracts; July 25-29; Herceg Novi, Montenegro
T1  - Determination of radionuclide concentrations in soil and black walnut leaves and fruit using gamma-ray spectrometry
SP  - 114
DO  - 10.21175/rad.sum.abstr.book.2022.27.5
ER  - 
@conference{
author = "Đurašević, Mirjana M. and Kandić, Aleksandar and Čeliković, Igor T. and Rajković, Katarina and Kandić, Irina and Obradović, Zorica",
year = "2022",
abstract = "This study showed that 137Cs concentrations in black walnut leaf and fruit, as well as in tinctures were below the detection limits. Concentrations of other radionuclides are lower than their concentrations in the soil, except for concentration of 40K in black walnut fruit, which objectively have more potassium due to the structure of the fruit. It indicates that the consumption of leaf and nut tinctureis absolutely safe, especially in relation to artificial radionuclides.",
publisher = "RAD Centre, Niš, Serbia",
journal = "RAD 2022 : 10th Jubilee International Conference on Radiation in Various Fields of Research : book of abstracts; July 25-29; Herceg Novi, Montenegro",
title = "Determination of radionuclide concentrations in soil and black walnut leaves and fruit using gamma-ray spectrometry",
pages = "114",
doi = "10.21175/rad.sum.abstr.book.2022.27.5"
}
Đurašević, M. M., Kandić, A., Čeliković, I. T., Rajković, K., Kandić, I.,& Obradović, Z.. (2022). Determination of radionuclide concentrations in soil and black walnut leaves and fruit using gamma-ray spectrometry. in RAD 2022 : 10th Jubilee International Conference on Radiation in Various Fields of Research : book of abstracts; July 25-29; Herceg Novi, Montenegro
RAD Centre, Niš, Serbia., 114.
https://doi.org/10.21175/rad.sum.abstr.book.2022.27.5
Đurašević MM, Kandić A, Čeliković IT, Rajković K, Kandić I, Obradović Z. Determination of radionuclide concentrations in soil and black walnut leaves and fruit using gamma-ray spectrometry. in RAD 2022 : 10th Jubilee International Conference on Radiation in Various Fields of Research : book of abstracts; July 25-29; Herceg Novi, Montenegro. 2022;:114.
doi:10.21175/rad.sum.abstr.book.2022.27.5 .
Đurašević, Mirjana M., Kandić, Aleksandar, Čeliković, Igor T., Rajković, Katarina, Kandić, Irina, Obradović, Zorica, "Determination of radionuclide concentrations in soil and black walnut leaves and fruit using gamma-ray spectrometry" in RAD 2022 : 10th Jubilee International Conference on Radiation in Various Fields of Research : book of abstracts; July 25-29; Herceg Novi, Montenegro (2022):114,
https://doi.org/10.21175/rad.sum.abstr.book.2022.27.5 . .

The effect of Juglans nigra L. green husk extracts on the biodistribution of radiopharmaceutical sodium pertechnetate in mice

Rajković, Katarina; Đurašević, Mirjana M.; Milanović, Zorana; Vranješ-Đurić, Sanja; Janković, Drina; Mirković, Marija; Obradović, Zorica

(RAD Centre, Niš, Serbia, 2022)

TY  - CONF
AU  - Rajković, Katarina
AU  - Đurašević, Mirjana M.
AU  - Milanović, Zorana
AU  - Vranješ-Đurić, Sanja
AU  - Janković, Drina
AU  - Mirković, Marija
AU  - Obradović, Zorica
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/11109
AB  - Juglans nigra L. (Black walnut) green husk contains a variety of useful chemical compounds with numerous health benefits. However, the biological effects of these compounds are not fully known. The aim of this research was to evaluate the effect of the extracts from J. nigra green husks on the biodistribution of the sodium pertechenetate (Na99mTcO4). The extract was orally administered to the healthy Wistar rats (male, 1-month-old, weighing 89.4±3.4g) at single doses of 13.7 mg/kg/day by gavage for 10 days. On the eleventh day, 0.1 ml (approximately 148 kBq) of the Na99mTcO4 was injected into the tail vein. Rats were sacrificed at different time intervals and the radioactivity in the organs of interest was measured in a gamma counter with a NaI (Tl) detector. The percentage of radioactivity per organ (%ID/organ) was calculated. The organ uptake of the Na99mTcO4 in an additional control group of animals was also studied. The results obtained showed an alteration in the organ uptake of Na99mTcO4 in rats treated with extract. The radiopharmaceutical Na99mTcO4 is generally distributed throughout the vasculature and interstitial fluid and is concentrated in the stomach, intestinal tract, thyroid and salivary glands. After treatment of rats with the extract, there was a statistically significant decrease (p<0.05) in the uptake of Na99mTcO4 (%ID/organ) in the thyroid, heart, kidneys, liver and colon, and an increase in intestinal uptake compared to controls. These results are associated with properties of the chemical compounds present in the J. nigra extract. We assume that the compounds from the extract J. nigra could promote physiological modifications in these organs and alter the biodistribution of Na99mTcO4 in the treated animals. Although these research studies were performed in animals, the findings suggest that caution should be exercised while interpreting the results of Na99mTcO4 based nuclear medicine examinations in patients using J. nigra extract from green husk.
PB  - RAD Centre, Niš, Serbia
C3  - RAD 2022 : 10th Jubilee International Conference on Radiation in Various Fields of Research : book of abstracts; July 25-29; Herceg Novi, Montenegro
T1  - The effect of Juglans nigra L. green husk extracts on the biodistribution of radiopharmaceutical sodium pertechnetate in mice
SP  - 119
DO  - 10.21175/rad.sum.abstr.book.2022.29.1
ER  - 
@conference{
author = "Rajković, Katarina and Đurašević, Mirjana M. and Milanović, Zorana and Vranješ-Đurić, Sanja and Janković, Drina and Mirković, Marija and Obradović, Zorica",
year = "2022",
abstract = "Juglans nigra L. (Black walnut) green husk contains a variety of useful chemical compounds with numerous health benefits. However, the biological effects of these compounds are not fully known. The aim of this research was to evaluate the effect of the extracts from J. nigra green husks on the biodistribution of the sodium pertechenetate (Na99mTcO4). The extract was orally administered to the healthy Wistar rats (male, 1-month-old, weighing 89.4±3.4g) at single doses of 13.7 mg/kg/day by gavage for 10 days. On the eleventh day, 0.1 ml (approximately 148 kBq) of the Na99mTcO4 was injected into the tail vein. Rats were sacrificed at different time intervals and the radioactivity in the organs of interest was measured in a gamma counter with a NaI (Tl) detector. The percentage of radioactivity per organ (%ID/organ) was calculated. The organ uptake of the Na99mTcO4 in an additional control group of animals was also studied. The results obtained showed an alteration in the organ uptake of Na99mTcO4 in rats treated with extract. The radiopharmaceutical Na99mTcO4 is generally distributed throughout the vasculature and interstitial fluid and is concentrated in the stomach, intestinal tract, thyroid and salivary glands. After treatment of rats with the extract, there was a statistically significant decrease (p<0.05) in the uptake of Na99mTcO4 (%ID/organ) in the thyroid, heart, kidneys, liver and colon, and an increase in intestinal uptake compared to controls. These results are associated with properties of the chemical compounds present in the J. nigra extract. We assume that the compounds from the extract J. nigra could promote physiological modifications in these organs and alter the biodistribution of Na99mTcO4 in the treated animals. Although these research studies were performed in animals, the findings suggest that caution should be exercised while interpreting the results of Na99mTcO4 based nuclear medicine examinations in patients using J. nigra extract from green husk.",
publisher = "RAD Centre, Niš, Serbia",
journal = "RAD 2022 : 10th Jubilee International Conference on Radiation in Various Fields of Research : book of abstracts; July 25-29; Herceg Novi, Montenegro",
title = "The effect of Juglans nigra L. green husk extracts on the biodistribution of radiopharmaceutical sodium pertechnetate in mice",
pages = "119",
doi = "10.21175/rad.sum.abstr.book.2022.29.1"
}
Rajković, K., Đurašević, M. M., Milanović, Z., Vranješ-Đurić, S., Janković, D., Mirković, M.,& Obradović, Z.. (2022). The effect of Juglans nigra L. green husk extracts on the biodistribution of radiopharmaceutical sodium pertechnetate in mice. in RAD 2022 : 10th Jubilee International Conference on Radiation in Various Fields of Research : book of abstracts; July 25-29; Herceg Novi, Montenegro
RAD Centre, Niš, Serbia., 119.
https://doi.org/10.21175/rad.sum.abstr.book.2022.29.1
Rajković K, Đurašević MM, Milanović Z, Vranješ-Đurić S, Janković D, Mirković M, Obradović Z. The effect of Juglans nigra L. green husk extracts on the biodistribution of radiopharmaceutical sodium pertechnetate in mice. in RAD 2022 : 10th Jubilee International Conference on Radiation in Various Fields of Research : book of abstracts; July 25-29; Herceg Novi, Montenegro. 2022;:119.
doi:10.21175/rad.sum.abstr.book.2022.29.1 .
Rajković, Katarina, Đurašević, Mirjana M., Milanović, Zorana, Vranješ-Đurić, Sanja, Janković, Drina, Mirković, Marija, Obradović, Zorica, "The effect of Juglans nigra L. green husk extracts on the biodistribution of radiopharmaceutical sodium pertechnetate in mice" in RAD 2022 : 10th Jubilee International Conference on Radiation in Various Fields of Research : book of abstracts; July 25-29; Herceg Novi, Montenegro (2022):119,
https://doi.org/10.21175/rad.sum.abstr.book.2022.29.1 . .

Comparison of coincidence summing correction factors calculated by EFFTRAN and GESPECOR software

Kandić, Aleksandar; Čeliković, Igor T.; Obradović, Zorica; Milanović, Tamara; Vukanac, Ivana

(RAD Centre, Niš, Serbia, 2021)

TY  - CONF
AU  - Kandić, Aleksandar
AU  - Čeliković, Igor T.
AU  - Obradović, Zorica
AU  - Milanović, Tamara
AU  - Vukanac, Ivana
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/11127
AB  - Gamma ray spectrometry with high purity germanium (HPGe) detector is one of the most widely used methods for environmental samples measurements. It is basically a non-destructive method and usually there is no need for the extensive sample preparation. True coincidence summing effect has a significant effect in gamma ray spectrometry analysis, especially in low source-to-detector geometry. Many authors have paid attention to this problem mainly by analyzing and determining coincidence summing correction factors for artificial radionuclides. However, the effect of true coincidence summing can significantly affect the result obtained by gamma ray spectrometry of environmental samples. Therefore, special attention should be paid to the determination of correction factors for coincidence summing of radionuclides from natural series (uranium, thorium and actinium series). Coincidence summing correction factors can be determined in several manners. Application of appropriate software packages is one of the most common. Software packages EFFTRAN and GESPECOR are among the most used ones. These software are based on Monte Carlo simulation. EFFTRAN is efficiency transfer code with semiempirical approach, whereas GESPECOR is dedicated code specifically tailored to solve most of the problems concerning gamma spectrometric measurements. The values of the correction factors depend on the detector geometry as well as the relevant data related to analyzed sample. The geometry of the detector implies the parameters of the detector itself (crystal dimensions, thickness of the dead layer, the thickness of the detector window). On the other hand, the relevant data related to analyzed sample includes dimensions of the container in which the sample is packed, sample density, chemical composition. The aim of this work is to compare coincidence summing factors obtained by using EFFTRAN and GESPEOR software in the case of p-type semiconductor HPGe detector with 30 % relative efficiency. All coincidence summing correction factors were calculated for soil sample in the cylindrical geometry and for radionuclides which are usually analyzed for environmental samples: • for the uranium series: 214Pb for energies 295.22 keV and 351.93 keV; 214Bi for energies 609.32 keV, 1120.29 keV and 1764.54 keV;234mPa for energies 766.36 keV and 1001.03 keV. • for the thorium series: 212Pb for energies 238.63 keV and 300.09 keV; 208Tl for energy 583.19 keV; 212Bi for energy 727.33 keV; 228Ac for energies 911.2 keV and 968.97 keV. • for the actinium series: 235U for energies 143.76 keV, 163.33 keV, 185.71 keV and 205.31 keV. The obtained values of the correction factors for coincidence summing showed a good agreement between these two software packages. Mutual deviations between correction factors calculated by using EFFTRAN and GESPECOR software were within ± 3 %.
PB  - RAD Centre, Niš, Serbia
C3  - RAD 2021 : 9th International Conference on Radiation in Various Fields of Research : book of abstracts; June 14-18; Herceg Novi, Montenegro
T1  - Comparison of coincidence summing correction factors calculated by EFFTRAN and GESPECOR software
SP  - 186
DO  - 10.21175/rad.abstr.book.2021.28.8
ER  - 
@conference{
author = "Kandić, Aleksandar and Čeliković, Igor T. and Obradović, Zorica and Milanović, Tamara and Vukanac, Ivana",
year = "2021",
abstract = "Gamma ray spectrometry with high purity germanium (HPGe) detector is one of the most widely used methods for environmental samples measurements. It is basically a non-destructive method and usually there is no need for the extensive sample preparation. True coincidence summing effect has a significant effect in gamma ray spectrometry analysis, especially in low source-to-detector geometry. Many authors have paid attention to this problem mainly by analyzing and determining coincidence summing correction factors for artificial radionuclides. However, the effect of true coincidence summing can significantly affect the result obtained by gamma ray spectrometry of environmental samples. Therefore, special attention should be paid to the determination of correction factors for coincidence summing of radionuclides from natural series (uranium, thorium and actinium series). Coincidence summing correction factors can be determined in several manners. Application of appropriate software packages is one of the most common. Software packages EFFTRAN and GESPECOR are among the most used ones. These software are based on Monte Carlo simulation. EFFTRAN is efficiency transfer code with semiempirical approach, whereas GESPECOR is dedicated code specifically tailored to solve most of the problems concerning gamma spectrometric measurements. The values of the correction factors depend on the detector geometry as well as the relevant data related to analyzed sample. The geometry of the detector implies the parameters of the detector itself (crystal dimensions, thickness of the dead layer, the thickness of the detector window). On the other hand, the relevant data related to analyzed sample includes dimensions of the container in which the sample is packed, sample density, chemical composition. The aim of this work is to compare coincidence summing factors obtained by using EFFTRAN and GESPEOR software in the case of p-type semiconductor HPGe detector with 30 % relative efficiency. All coincidence summing correction factors were calculated for soil sample in the cylindrical geometry and for radionuclides which are usually analyzed for environmental samples: • for the uranium series: 214Pb for energies 295.22 keV and 351.93 keV; 214Bi for energies 609.32 keV, 1120.29 keV and 1764.54 keV;234mPa for energies 766.36 keV and 1001.03 keV. • for the thorium series: 212Pb for energies 238.63 keV and 300.09 keV; 208Tl for energy 583.19 keV; 212Bi for energy 727.33 keV; 228Ac for energies 911.2 keV and 968.97 keV. • for the actinium series: 235U for energies 143.76 keV, 163.33 keV, 185.71 keV and 205.31 keV. The obtained values of the correction factors for coincidence summing showed a good agreement between these two software packages. Mutual deviations between correction factors calculated by using EFFTRAN and GESPECOR software were within ± 3 %.",
publisher = "RAD Centre, Niš, Serbia",
journal = "RAD 2021 : 9th International Conference on Radiation in Various Fields of Research : book of abstracts; June 14-18; Herceg Novi, Montenegro",
title = "Comparison of coincidence summing correction factors calculated by EFFTRAN and GESPECOR software",
pages = "186",
doi = "10.21175/rad.abstr.book.2021.28.8"
}
Kandić, A., Čeliković, I. T., Obradović, Z., Milanović, T.,& Vukanac, I.. (2021). Comparison of coincidence summing correction factors calculated by EFFTRAN and GESPECOR software. in RAD 2021 : 9th International Conference on Radiation in Various Fields of Research : book of abstracts; June 14-18; Herceg Novi, Montenegro
RAD Centre, Niš, Serbia., 186.
https://doi.org/10.21175/rad.abstr.book.2021.28.8
Kandić A, Čeliković IT, Obradović Z, Milanović T, Vukanac I. Comparison of coincidence summing correction factors calculated by EFFTRAN and GESPECOR software. in RAD 2021 : 9th International Conference on Radiation in Various Fields of Research : book of abstracts; June 14-18; Herceg Novi, Montenegro. 2021;:186.
doi:10.21175/rad.abstr.book.2021.28.8 .
Kandić, Aleksandar, Čeliković, Igor T., Obradović, Zorica, Milanović, Tamara, Vukanac, Ivana, "Comparison of coincidence summing correction factors calculated by EFFTRAN and GESPECOR software" in RAD 2021 : 9th International Conference on Radiation in Various Fields of Research : book of abstracts; June 14-18; Herceg Novi, Montenegro (2021):186,
https://doi.org/10.21175/rad.abstr.book.2021.28.8 . .

Dugovremenska stabilnost kalibracionih standarda različitih matriksa u gamaspektrometriji

Đurašević, Mirjana M.; Kandić, Aleksandar; Vukanac, Ivana; Čeliković, Igor T.; Mladenović-Nikolić, Nataša; Milanović, Tamara J.; Obradović, Zorica

(Institut za nuklearne nauke "Vinča", 2021)

TY  - CONF
AU  - Đurašević, Mirjana M.
AU  - Kandić, Aleksandar
AU  - Vukanac, Ivana
AU  - Čeliković, Igor T.
AU  - Mladenović-Nikolić, Nataša
AU  - Milanović, Tamara J.
AU  - Obradović, Zorica
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10011
AB  - Da bi se postigla tačnost i preciznost dobijenih rezultata pri gamaspektrometrijskom merenju uzoraka iz životne sredine neophodno je obezbediti odgovarajuće kalibracione standarde. Imajući u vidu da i sami standardi vremenom gube na kvalitetu zbog degradacije matriksa, od izuzetne je važnosti praćenje stabilnosti standarda koji se koriste. U ovom radu prikazani su rezultati ispitivanja karakteristika krivih efikasnosti u odnosu na starenje matriksa. Napravljeni su radni kalibracioni standardi sa tri različita matriksa (aktivni ugalj, zemlja i pesak), upakovani u cilindričnu geometriju kutijice od 120 ml i 250 ml i mereni na poluprovodničkom HPGe detektoru. Isti standardi ponovo su mereni nakon četiri godine u kontakt geometriji u odnosu na detektor i izvrnuto sa poklopcem kutijice ka detektoru. Analiza dobijenih rezultata pokazala je odstupanja u vrednostima efikasnosti, što ukazuje na degradaciju svih standarda u smislu narušavanja njihove homogenosti. Takvi standardi se ne mogu smatrati pouzdanim za korišćenje.
AB  - The gammaspectrometric measurement of the environmental samples requires the use of appropriate calibration standards in order to achieve the accuracy and precision of the obtained results. Taking into account that the standards lose their quality over time due to the degradation of the matrix, it is extremely important to keep tracking their stability. Comprehensive reconsideration on efficiency curves with respect to the ageing of calibration standards is presented in this paper. Spiked laboratory standards of different matrices (active coal, soil and sand) were prepared in two measurement geometries, PVC cylindrical 120 ml and 250 ml boxes. The same standards were measured after four years in contact geometry on the detector and upside down (box cover towards the detector). The analysis of the obtained results showed discrepancies in efficiency values and it indicates that the homogeneity of standards is disturbed. Such standards are not reliable for use.
PB  - Institut za nuklearne nauke "Vinča"
PB  - Društvo za zaštitu od zračenja Srbije i Crne Gore
C3  - 31. симпозијум ДЗЗСЦГ : зборник радова
T1  - Dugovremenska stabilnost kalibracionih standarda različitih matriksa u gamaspektrometriji
T1  - On the Long-Term Stability of the Calibration Standards in Different Matrices for Gamma-Ray Spectrometry
SP  - 181
EP  - 186
UR  - https://hdl.handle.net/21.15107/rcub_vinar_10011
ER  - 
@conference{
author = "Đurašević, Mirjana M. and Kandić, Aleksandar and Vukanac, Ivana and Čeliković, Igor T. and Mladenović-Nikolić, Nataša and Milanović, Tamara J. and Obradović, Zorica",
year = "2021",
abstract = "Da bi se postigla tačnost i preciznost dobijenih rezultata pri gamaspektrometrijskom merenju uzoraka iz životne sredine neophodno je obezbediti odgovarajuće kalibracione standarde. Imajući u vidu da i sami standardi vremenom gube na kvalitetu zbog degradacije matriksa, od izuzetne je važnosti praćenje stabilnosti standarda koji se koriste. U ovom radu prikazani su rezultati ispitivanja karakteristika krivih efikasnosti u odnosu na starenje matriksa. Napravljeni su radni kalibracioni standardi sa tri različita matriksa (aktivni ugalj, zemlja i pesak), upakovani u cilindričnu geometriju kutijice od 120 ml i 250 ml i mereni na poluprovodničkom HPGe detektoru. Isti standardi ponovo su mereni nakon četiri godine u kontakt geometriji u odnosu na detektor i izvrnuto sa poklopcem kutijice ka detektoru. Analiza dobijenih rezultata pokazala je odstupanja u vrednostima efikasnosti, što ukazuje na degradaciju svih standarda u smislu narušavanja njihove homogenosti. Takvi standardi se ne mogu smatrati pouzdanim za korišćenje., The gammaspectrometric measurement of the environmental samples requires the use of appropriate calibration standards in order to achieve the accuracy and precision of the obtained results. Taking into account that the standards lose their quality over time due to the degradation of the matrix, it is extremely important to keep tracking their stability. Comprehensive reconsideration on efficiency curves with respect to the ageing of calibration standards is presented in this paper. Spiked laboratory standards of different matrices (active coal, soil and sand) were prepared in two measurement geometries, PVC cylindrical 120 ml and 250 ml boxes. The same standards were measured after four years in contact geometry on the detector and upside down (box cover towards the detector). The analysis of the obtained results showed discrepancies in efficiency values and it indicates that the homogeneity of standards is disturbed. Such standards are not reliable for use.",
publisher = "Institut za nuklearne nauke "Vinča", Društvo za zaštitu od zračenja Srbije i Crne Gore",
journal = "31. симпозијум ДЗЗСЦГ : зборник радова",
title = "Dugovremenska stabilnost kalibracionih standarda različitih matriksa u gamaspektrometriji, On the Long-Term Stability of the Calibration Standards in Different Matrices for Gamma-Ray Spectrometry",
pages = "181-186",
url = "https://hdl.handle.net/21.15107/rcub_vinar_10011"
}
Đurašević, M. M., Kandić, A., Vukanac, I., Čeliković, I. T., Mladenović-Nikolić, N., Milanović, T. J.,& Obradović, Z.. (2021). Dugovremenska stabilnost kalibracionih standarda različitih matriksa u gamaspektrometriji. in 31. симпозијум ДЗЗСЦГ : зборник радова
Institut za nuklearne nauke "Vinča"., 181-186.
https://hdl.handle.net/21.15107/rcub_vinar_10011
Đurašević MM, Kandić A, Vukanac I, Čeliković IT, Mladenović-Nikolić N, Milanović TJ, Obradović Z. Dugovremenska stabilnost kalibracionih standarda različitih matriksa u gamaspektrometriji. in 31. симпозијум ДЗЗСЦГ : зборник радова. 2021;:181-186.
https://hdl.handle.net/21.15107/rcub_vinar_10011 .
Đurašević, Mirjana M., Kandić, Aleksandar, Vukanac, Ivana, Čeliković, Igor T., Mladenović-Nikolić, Nataša, Milanović, Tamara J., Obradović, Zorica, "Dugovremenska stabilnost kalibracionih standarda različitih matriksa u gamaspektrometriji" in 31. симпозијум ДЗЗСЦГ : зборник радова (2021):181-186,
https://hdl.handle.net/21.15107/rcub_vinar_10011 .

Primena zakonske regulative pri korišćenju izvora jonizujućih zračenja u industriji

Obradović, Zorica; Đurašević, Mirjana M.; Rajković, Katarina

(Institut za nuklearne nauke "Vinča", 2021)

TY  - CONF
AU  - Obradović, Zorica
AU  - Đurašević, Mirjana M.
AU  - Rajković, Katarina
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10127
AB  - Razvoj industrije doveo je do sve veće primene izvora jonizujućih zračenja, bilo da su to zatvoreni radioaktivni izvori u okviru mernih uređaja ili generatori jonizujućih zračenja. Važeća zakonska regulativa zahteva da svi koji rukuju sa izvorima jonizujućih zračenja moraju pre početka rada u zoni zračenja proći odgovarajuću obuku kako bi stekli potrebna znanja o samim izvorima jonizujućih zračenja, rizicima njihove primene i merama zaštite od jonizujućih zračenja u situacijama planiranog ili vanrednog izlaganja. Centar za permanentno obrazovanje je deo Instituta za nuklearne nauke „Vinča” koji se dugi niz godina bavi dopunskim i stručnim obučavanjem i osposobljavanjem izloženih radnika i lica odgovornih za sprovođenje mera zaštite od jonizujućih zračenja. U ovom radu su prikazani rezultati koje je ostvario Centar za permanentno obrazovanje u okviru edukacije izloženih radnika i lica odgovornih za sprovođenje mera zaštite od jonizujućih zračenja u oblasti industrije u periodu od 2011. godine do 2020. godine. Analizom tih rezultata može se pratiti uspešnost primene najnovije zakonske regulative u sprovođenju mera zaštite pri korišćenju izvora jonizujućih zračenja u industriji.
AB  - The industry development has led to the increasing industrial aplication of radiation sources, as closed radiation sources or radiation generators. They have been widely used by various industries to improve the quality of product, optimize processes, save energy and materials. Any aplication of radiation sources implies the need for appropriate radiation protection in order to reduce unnecessary exposure of people who work with radiation sources in the situation of planned and emergency exposure. International commission of radiation protection (ICRP) suggested general principles of radiation protection in terms of three key words: justification, optimization and dose limit. Center for permanent education (CPE) of the “Vinča“ Institute of nuclear sciences is a unique educational institution in Serbia. The main objective of the CPE is an additional and complementary education of various profiles of specialists who use sources of ionizing radiation in their everyday work. The results of the CPE in the education of exposed workers and radiation protection officers in the industry aplication for the period from 2011 to 2020 are presented in this paper. The analysis of these results shows the success of the application of regulations in industrial usage of radiation sources.
PB  - Institut za nuklearne nauke "Vinča"
PB  - Društvo za zaštitu od zračenja Srbije i Crne Gore
C3  - 31. симпозијум ДЗЗСЦГ : зборник радова
T1  - Primena zakonske regulative pri korišćenju izvora jonizujućih zračenja u industriji
T1  - Application of Legislation Regarding the Use of Radiation Sources in Industry
SP  - 332
EP  - 337
UR  - https://hdl.handle.net/21.15107/rcub_vinar_10127
ER  - 
@conference{
author = "Obradović, Zorica and Đurašević, Mirjana M. and Rajković, Katarina",
year = "2021",
abstract = "Razvoj industrije doveo je do sve veće primene izvora jonizujućih zračenja, bilo da su to zatvoreni radioaktivni izvori u okviru mernih uređaja ili generatori jonizujućih zračenja. Važeća zakonska regulativa zahteva da svi koji rukuju sa izvorima jonizujućih zračenja moraju pre početka rada u zoni zračenja proći odgovarajuću obuku kako bi stekli potrebna znanja o samim izvorima jonizujućih zračenja, rizicima njihove primene i merama zaštite od jonizujućih zračenja u situacijama planiranog ili vanrednog izlaganja. Centar za permanentno obrazovanje je deo Instituta za nuklearne nauke „Vinča” koji se dugi niz godina bavi dopunskim i stručnim obučavanjem i osposobljavanjem izloženih radnika i lica odgovornih za sprovođenje mera zaštite od jonizujućih zračenja. U ovom radu su prikazani rezultati koje je ostvario Centar za permanentno obrazovanje u okviru edukacije izloženih radnika i lica odgovornih za sprovođenje mera zaštite od jonizujućih zračenja u oblasti industrije u periodu od 2011. godine do 2020. godine. Analizom tih rezultata može se pratiti uspešnost primene najnovije zakonske regulative u sprovođenju mera zaštite pri korišćenju izvora jonizujućih zračenja u industriji., The industry development has led to the increasing industrial aplication of radiation sources, as closed radiation sources or radiation generators. They have been widely used by various industries to improve the quality of product, optimize processes, save energy and materials. Any aplication of radiation sources implies the need for appropriate radiation protection in order to reduce unnecessary exposure of people who work with radiation sources in the situation of planned and emergency exposure. International commission of radiation protection (ICRP) suggested general principles of radiation protection in terms of three key words: justification, optimization and dose limit. Center for permanent education (CPE) of the “Vinča“ Institute of nuclear sciences is a unique educational institution in Serbia. The main objective of the CPE is an additional and complementary education of various profiles of specialists who use sources of ionizing radiation in their everyday work. The results of the CPE in the education of exposed workers and radiation protection officers in the industry aplication for the period from 2011 to 2020 are presented in this paper. The analysis of these results shows the success of the application of regulations in industrial usage of radiation sources.",
publisher = "Institut za nuklearne nauke "Vinča", Društvo za zaštitu od zračenja Srbije i Crne Gore",
journal = "31. симпозијум ДЗЗСЦГ : зборник радова",
title = "Primena zakonske regulative pri korišćenju izvora jonizujućih zračenja u industriji, Application of Legislation Regarding the Use of Radiation Sources in Industry",
pages = "332-337",
url = "https://hdl.handle.net/21.15107/rcub_vinar_10127"
}
Obradović, Z., Đurašević, M. M.,& Rajković, K.. (2021). Primena zakonske regulative pri korišćenju izvora jonizujućih zračenja u industriji. in 31. симпозијум ДЗЗСЦГ : зборник радова
Institut za nuklearne nauke "Vinča"., 332-337.
https://hdl.handle.net/21.15107/rcub_vinar_10127
Obradović Z, Đurašević MM, Rajković K. Primena zakonske regulative pri korišćenju izvora jonizujućih zračenja u industriji. in 31. симпозијум ДЗЗСЦГ : зборник радова. 2021;:332-337.
https://hdl.handle.net/21.15107/rcub_vinar_10127 .
Obradović, Zorica, Đurašević, Mirjana M., Rajković, Katarina, "Primena zakonske regulative pri korišćenju izvora jonizujućih zračenja u industriji" in 31. симпозијум ДЗЗСЦГ : зборник радова (2021):332-337,
https://hdl.handle.net/21.15107/rcub_vinar_10127 .

Achieved results in radiation protection education of the Center for Permanent Education INN “Vinča”

Đurašević, Mirjana M.; Obradović, Zorica; Rajković, Katarina

(RAD Centre, Niš, Serbia, 2021)

TY  - CONF
AU  - Đurašević, Mirjana M.
AU  - Obradović, Zorica
AU  - Rajković, Katarina
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/11131
AB  - The Center for permanent education (CPE) of the “Vinča” Institute of nuclear sciences is a unique educational institution in Serbia. The main objective of the CPE is an additional and complementary education of various profiles of specialists who use radioactive isotopes and sources of ionizing radiation in their everyday work in accordance with the Law on Radiation and Nuclear Safety and Security of Serbia. Application of ionizing radiation in various fields of activity (industry, medicine, scientific research) carries the appropriate risks to the health and safety of those who work with ionizing radiation sources. It is therefore crucial that the handling of radioactive sources and ionizing radiation generators, as well as the handling of nuclear waste, be in line with certain safety standards aimed at protecting those exposed to ionizing radiation. Center for Permanent Education is authorized by the Directorate for Radiation and Nuclear Safety and Security of Serbia to provide additional training and education for occupationally exposed persons and persons responsible for implementing measures radiation protection. Accordingly, the activities of the Center are focused on the organization of different types of courses, depending on the category of a particular radiation activity. Permanent education program defines: additional and appropriate training before beginning work with radiation sources, training of persons responsible for implementing radiation protection measures, and periodic renewal of knowledge provided for all occupationally exposed persons at least once in five years. The special type of courses refers to courses for work with open sources of radiation, where longer and more detailed training is required. The aim of this work is to present the achieved results related to the number of held courses and the number of participants between 2011 and 2020, as well as years with the most and the least held courses and years with the largest and the smallest number of participants. These numbers have been changed in accordance with the requirements of legal regulations related to radiation protection. The Center for permanent education has worked since 1956, but information about all courses and candidates have been kept within database program only since 2011. During that period, 1503 different courses were held related to radiation protection. The most courses (272) were held in 2018 and the least (43) in 2011. Regarding the number of candidates, 5805 candidates completed the courses in the period between 2011 and to 2020. The largest number of candidates (1036) were in 2018, and the smallest (185) in 2013. The CPE aims to improve the quality of its services and strives to continuously follow and introduce modern and new methods of education for the next period.
PB  - RAD Centre, Niš, Serbia
C3  - RAD 2021 : 9th International Conference on Radiation in Various Fields of Research : book of abstracts; June 14-18; Herceg Novi, Montenegro
T1  - Achieved results in radiation protection education of the Center for Permanent Education INN “Vinča”
SP  - 299
DO  - 10.21175/rad.abstr.book.2021.38.4
ER  - 
@conference{
author = "Đurašević, Mirjana M. and Obradović, Zorica and Rajković, Katarina",
year = "2021",
abstract = "The Center for permanent education (CPE) of the “Vinča” Institute of nuclear sciences is a unique educational institution in Serbia. The main objective of the CPE is an additional and complementary education of various profiles of specialists who use radioactive isotopes and sources of ionizing radiation in their everyday work in accordance with the Law on Radiation and Nuclear Safety and Security of Serbia. Application of ionizing radiation in various fields of activity (industry, medicine, scientific research) carries the appropriate risks to the health and safety of those who work with ionizing radiation sources. It is therefore crucial that the handling of radioactive sources and ionizing radiation generators, as well as the handling of nuclear waste, be in line with certain safety standards aimed at protecting those exposed to ionizing radiation. Center for Permanent Education is authorized by the Directorate for Radiation and Nuclear Safety and Security of Serbia to provide additional training and education for occupationally exposed persons and persons responsible for implementing measures radiation protection. Accordingly, the activities of the Center are focused on the organization of different types of courses, depending on the category of a particular radiation activity. Permanent education program defines: additional and appropriate training before beginning work with radiation sources, training of persons responsible for implementing radiation protection measures, and periodic renewal of knowledge provided for all occupationally exposed persons at least once in five years. The special type of courses refers to courses for work with open sources of radiation, where longer and more detailed training is required. The aim of this work is to present the achieved results related to the number of held courses and the number of participants between 2011 and 2020, as well as years with the most and the least held courses and years with the largest and the smallest number of participants. These numbers have been changed in accordance with the requirements of legal regulations related to radiation protection. The Center for permanent education has worked since 1956, but information about all courses and candidates have been kept within database program only since 2011. During that period, 1503 different courses were held related to radiation protection. The most courses (272) were held in 2018 and the least (43) in 2011. Regarding the number of candidates, 5805 candidates completed the courses in the period between 2011 and to 2020. The largest number of candidates (1036) were in 2018, and the smallest (185) in 2013. The CPE aims to improve the quality of its services and strives to continuously follow and introduce modern and new methods of education for the next period.",
publisher = "RAD Centre, Niš, Serbia",
journal = "RAD 2021 : 9th International Conference on Radiation in Various Fields of Research : book of abstracts; June 14-18; Herceg Novi, Montenegro",
title = "Achieved results in radiation protection education of the Center for Permanent Education INN “Vinča”",
pages = "299",
doi = "10.21175/rad.abstr.book.2021.38.4"
}
Đurašević, M. M., Obradović, Z.,& Rajković, K.. (2021). Achieved results in radiation protection education of the Center for Permanent Education INN “Vinča”. in RAD 2021 : 9th International Conference on Radiation in Various Fields of Research : book of abstracts; June 14-18; Herceg Novi, Montenegro
RAD Centre, Niš, Serbia., 299.
https://doi.org/10.21175/rad.abstr.book.2021.38.4
Đurašević MM, Obradović Z, Rajković K. Achieved results in radiation protection education of the Center for Permanent Education INN “Vinča”. in RAD 2021 : 9th International Conference on Radiation in Various Fields of Research : book of abstracts; June 14-18; Herceg Novi, Montenegro. 2021;:299.
doi:10.21175/rad.abstr.book.2021.38.4 .
Đurašević, Mirjana M., Obradović, Zorica, Rajković, Katarina, "Achieved results in radiation protection education of the Center for Permanent Education INN “Vinča”" in RAD 2021 : 9th International Conference on Radiation in Various Fields of Research : book of abstracts; June 14-18; Herceg Novi, Montenegro (2021):299,
https://doi.org/10.21175/rad.abstr.book.2021.38.4 . .

Korišćenje virtuelnih programskih aplikacija u edukaciji

Đurašević, Mirjana M.; Obradović, Zorica; Rajković, Katarina

(Београд : Институт за нуклеарне науке "Винча" : Друштво за заштиту од зрачења Србије и Црне Горе, 2019)

TY  - CONF
AU  - Đurašević, Mirjana M.
AU  - Obradović, Zorica
AU  - Rajković, Katarina
PY  - 2019
UR  - https://plus.sr.cobiss.net/opac7/bib/279687436
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8724
AB  - Centar za permanentno obrazovanje kao deo Instituta za nuklearne nauke "Vinča" se dugi niz godina bavi dopunskim stručnim obrazovanjem i osposobljavanjem stručnjaka multidisciplinarnih profila koji u svom radu koriste radioaktivne materijale i generatore jonizujućih zračenja. Zajedničko za sve kurseve u Centru, osim visokog kvaliteta obuke, je i stalno praćenje i uvoĎenje savremenih i novih metoda edukacije. Sve veći razvoj informacionih tehnologija uticao je i na razvoj metoda i tehnika u samomobrazovanju. Najnoviji trend u edukaciji je da se realne laboratorije zamenjuju virtuelnim laboratorijama. Zaposleni u Centru za permanentno obrazovanje odlučili su da svoje kurseve oplemene i obogate primenom virtuelnih programskih aplikacija koje će pomoći da se polaznicima kurseva na jednostavan, lak i zabavan način približe osnovni pojmovi vezani za siguran i bezbedan rad sa radioaktivnim izvorima i generatorima jonizujućih zračenja poštujući sve mere zaštite od jonizujućih zračenja. U ovom radu prikazane su neke od virtuelnih aplikacija koje se koristeu okviru praktičnih vežbi na kursevima iz oblasti osnova radijacione fizike i osnovnih principa zaštite od jonizujućih zračenja.
AB  - Center for permanent education (CPE) of the "Vinča" Institute of nuclear sciences is a unique educational institution in Serbia. The main objective of the CPE is an additional and complementary education of various profiles of specialists who use radioactive isotopes and sources of ionizing radiation in their everyday work. The CPE aims to improve the quality of its services and strives to continuously follow and introduce modern and new methods of education. The increasing development of information technologies has influenced the development of methods and techniques in the education itself. The latest trend in education is to replace the real laboratories with the virtual ones. The employees of the Center for Permanent Education have, therefore, decided to enrich the CPE courses with virtual software applications. Their use explains the basic concepts of ionizing radiation protection and safety in a simple, easy and fun way. In this paper, we describe some of the virtual software applications that are used in the laboratory curriculum of the CPE courses aimed at furthering education of professionals who work with radioactive sources and generators of ionizing radiation.
PB  - Београд : Институт за нуклеарне науке "Винча" : Друштво за заштиту од зрачења Србије и Црне Горе
C3  - 30. симпозијум ДЗЗСЦГ : зборник радова
T1  - Korišćenje virtuelnih programskih aplikacija u edukaciji
T1  - Using virtual software applications in education
SP  - 616
EP  - 621
UR  - https://hdl.handle.net/21.15107/rcub_vinar_8724
ER  - 
@conference{
author = "Đurašević, Mirjana M. and Obradović, Zorica and Rajković, Katarina",
year = "2019",
abstract = "Centar za permanentno obrazovanje kao deo Instituta za nuklearne nauke "Vinča" se dugi niz godina bavi dopunskim stručnim obrazovanjem i osposobljavanjem stručnjaka multidisciplinarnih profila koji u svom radu koriste radioaktivne materijale i generatore jonizujućih zračenja. Zajedničko za sve kurseve u Centru, osim visokog kvaliteta obuke, je i stalno praćenje i uvoĎenje savremenih i novih metoda edukacije. Sve veći razvoj informacionih tehnologija uticao je i na razvoj metoda i tehnika u samomobrazovanju. Najnoviji trend u edukaciji je da se realne laboratorije zamenjuju virtuelnim laboratorijama. Zaposleni u Centru za permanentno obrazovanje odlučili su da svoje kurseve oplemene i obogate primenom virtuelnih programskih aplikacija koje će pomoći da se polaznicima kurseva na jednostavan, lak i zabavan način približe osnovni pojmovi vezani za siguran i bezbedan rad sa radioaktivnim izvorima i generatorima jonizujućih zračenja poštujući sve mere zaštite od jonizujućih zračenja. U ovom radu prikazane su neke od virtuelnih aplikacija koje se koristeu okviru praktičnih vežbi na kursevima iz oblasti osnova radijacione fizike i osnovnih principa zaštite od jonizujućih zračenja., Center for permanent education (CPE) of the "Vinča" Institute of nuclear sciences is a unique educational institution in Serbia. The main objective of the CPE is an additional and complementary education of various profiles of specialists who use radioactive isotopes and sources of ionizing radiation in their everyday work. The CPE aims to improve the quality of its services and strives to continuously follow and introduce modern and new methods of education. The increasing development of information technologies has influenced the development of methods and techniques in the education itself. The latest trend in education is to replace the real laboratories with the virtual ones. The employees of the Center for Permanent Education have, therefore, decided to enrich the CPE courses with virtual software applications. Their use explains the basic concepts of ionizing radiation protection and safety in a simple, easy and fun way. In this paper, we describe some of the virtual software applications that are used in the laboratory curriculum of the CPE courses aimed at furthering education of professionals who work with radioactive sources and generators of ionizing radiation.",
publisher = "Београд : Институт за нуклеарне науке "Винча" : Друштво за заштиту од зрачења Србије и Црне Горе",
journal = "30. симпозијум ДЗЗСЦГ : зборник радова",
title = "Korišćenje virtuelnih programskih aplikacija u edukaciji, Using virtual software applications in education",
pages = "616-621",
url = "https://hdl.handle.net/21.15107/rcub_vinar_8724"
}
Đurašević, M. M., Obradović, Z.,& Rajković, K.. (2019). Korišćenje virtuelnih programskih aplikacija u edukaciji. in 30. симпозијум ДЗЗСЦГ : зборник радова
Београд : Институт за нуклеарне науке "Винча" : Друштво за заштиту од зрачења Србије и Црне Горе., 616-621.
https://hdl.handle.net/21.15107/rcub_vinar_8724
Đurašević MM, Obradović Z, Rajković K. Korišćenje virtuelnih programskih aplikacija u edukaciji. in 30. симпозијум ДЗЗСЦГ : зборник радова. 2019;:616-621.
https://hdl.handle.net/21.15107/rcub_vinar_8724 .
Đurašević, Mirjana M., Obradović, Zorica, Rajković, Katarina, "Korišćenje virtuelnih programskih aplikacija u edukaciji" in 30. симпозијум ДЗЗСЦГ : зборник радова (2019):616-621,
https://hdl.handle.net/21.15107/rcub_vinar_8724 .

Concentration Of The 241Pu In Air Samples From Chernobyl At Belgrade Site Estimated By a 241Am In Growth Method

Vukanac, Ivana; Novković, Dušan; Đurašević, Mirjana; Obradović, Zorica; Kandić, Aleksandar

(2006)

TY  - CONF
AU  - Vukanac, Ivana
AU  - Novković, Dušan
AU  - Đurašević, Mirjana
AU  - Obradović, Zorica
AU  - Kandić, Aleksandar
PY  - 2006
PY  - S54
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12799
AB  - The surface air samples collected in the first half of May 1986 at VinčaBelgrade site were prepared and measured at the end of the 1991 and beginning of the 1992. year. Activity concentrations of the 137Cs immediately after the Chernobyl accident were determined by means of gamma spectrometry, while the air activity concentration of 238Pu and 239,240Pu were determined by alpha spectrometry, after the plutonium radiochemical separation. The 236Pu was used as a tracer. The same samples were remeasured after 13 years, during the 2004. The surface air activity concentrations of 241Pu were estimated by a 241Am in-growth method. The built up activities of 236Pu progenies were determined from the recorded spectra and also calculated using the Bateman’s equations. The 241Am activity in the remeasured samples, obtained by complex spectral analysis was confirmed by gamma spectrometry. The 241Pu activity concentration in measured air samples ranged from 240 µBq/m3  to 7800 µBq/m3 . The average activity concentration ratio 241Pu/239,240Pu originated from Chernobyl accident was approximately 100.
C3  - Environmental sciences
T1  - Concentration Of The 241Pu In Air Samples From Chernobyl At Belgrade Site Estimated By a 241Am In Growth Method
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12799
ER  - 
@conference{
author = "Vukanac, Ivana and Novković, Dušan and Đurašević, Mirjana and Obradović, Zorica and Kandić, Aleksandar",
year = "2006, S54",
abstract = "The surface air samples collected in the first half of May 1986 at VinčaBelgrade site were prepared and measured at the end of the 1991 and beginning of the 1992. year. Activity concentrations of the 137Cs immediately after the Chernobyl accident were determined by means of gamma spectrometry, while the air activity concentration of 238Pu and 239,240Pu were determined by alpha spectrometry, after the plutonium radiochemical separation. The 236Pu was used as a tracer. The same samples were remeasured after 13 years, during the 2004. The surface air activity concentrations of 241Pu were estimated by a 241Am in-growth method. The built up activities of 236Pu progenies were determined from the recorded spectra and also calculated using the Bateman’s equations. The 241Am activity in the remeasured samples, obtained by complex spectral analysis was confirmed by gamma spectrometry. The 241Pu activity concentration in measured air samples ranged from 240 µBq/m3  to 7800 µBq/m3 . The average activity concentration ratio 241Pu/239,240Pu originated from Chernobyl accident was approximately 100.",
journal = "Environmental sciences",
title = "Concentration Of The 241Pu In Air Samples From Chernobyl At Belgrade Site Estimated By a 241Am In Growth Method",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12799"
}
Vukanac, I., Novković, D., Đurašević, M., Obradović, Z.,& Kandić, A.. (2006). Concentration Of The 241Pu In Air Samples From Chernobyl At Belgrade Site Estimated By a 241Am In Growth Method. in Environmental sciences.
https://hdl.handle.net/21.15107/rcub_vinar_12799
Vukanac I, Novković D, Đurašević M, Obradović Z, Kandić A. Concentration Of The 241Pu In Air Samples From Chernobyl At Belgrade Site Estimated By a 241Am In Growth Method. in Environmental sciences. 2006;.
https://hdl.handle.net/21.15107/rcub_vinar_12799 .
Vukanac, Ivana, Novković, Dušan, Đurašević, Mirjana, Obradović, Zorica, Kandić, Aleksandar, "Concentration Of The 241Pu In Air Samples From Chernobyl At Belgrade Site Estimated By a 241Am In Growth Method" in Environmental sciences (2006),
https://hdl.handle.net/21.15107/rcub_vinar_12799 .

Merenje specifične alfa aktivnosti zemlje

Đurašević, Mirjana; Kandić, Aleksandar; Vukanac, Ivana; Obradović, Zorica

(Beograd : Privredna komora Srbije, 2005)

TY  - CONF
AU  - Đurašević, Mirjana
AU  - Kandić, Aleksandar
AU  - Vukanac, Ivana
AU  - Obradović, Zorica
PY  - 2005
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12818
AB  - U radu je predstavljena meloda za
odredivanje specifične alfa alclivnosti debelih izvora
scintilacionim ZnS(Ag) detektorom velike površine.
Metoda je zasnovana na primeni kvadratne zavisnosti
izntedu brzine bro.janja i debljine prozora deteldora.
Koeficijent uz linearni član se koristi za računanje specifične alfa aktivnosli debelog izvora u kontaktu sa
prozorom detektora. Za potvrdu teorijskih jednačina u
eksperimentu je korišćen spajkovan standard zemlje kontaminiran sa 232Th.
AB  - A method for determining the specific alpha
activity of thick sources using a large area ZnS(Ag) scintillation detector is presented A quadratic relationship between the detector response and window thickness is applied in this method. The coefficient of the linear term from this quadric expression is used to calculate the specific alpha activity of a thick source in contact with the window of the detector. The spiked standard of soil by 232Th is used in this experiment to prove theoretical assumption.
PB  - Beograd : Privredna komora Srbije
C3  - Životna sredina ka Evropi - Simpozijum sa međunarodnim učešćem : Zbornik radova
T1  - Merenje specifične alfa aktivnosti zemlje
SP  - 283
EP  - 286
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12818
ER  - 
@conference{
author = "Đurašević, Mirjana and Kandić, Aleksandar and Vukanac, Ivana and Obradović, Zorica",
year = "2005",
abstract = "U radu je predstavljena meloda za
odredivanje specifične alfa alclivnosti debelih izvora
scintilacionim ZnS(Ag) detektorom velike površine.
Metoda je zasnovana na primeni kvadratne zavisnosti
izntedu brzine bro.janja i debljine prozora deteldora.
Koeficijent uz linearni član se koristi za računanje specifične alfa aktivnosli debelog izvora u kontaktu sa
prozorom detektora. Za potvrdu teorijskih jednačina u
eksperimentu je korišćen spajkovan standard zemlje kontaminiran sa 232Th., A method for determining the specific alpha
activity of thick sources using a large area ZnS(Ag) scintillation detector is presented A quadratic relationship between the detector response and window thickness is applied in this method. The coefficient of the linear term from this quadric expression is used to calculate the specific alpha activity of a thick source in contact with the window of the detector. The spiked standard of soil by 232Th is used in this experiment to prove theoretical assumption.",
publisher = "Beograd : Privredna komora Srbije",
journal = "Životna sredina ka Evropi - Simpozijum sa međunarodnim učešćem : Zbornik radova",
title = "Merenje specifične alfa aktivnosti zemlje",
pages = "283-286",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12818"
}
Đurašević, M., Kandić, A., Vukanac, I.,& Obradović, Z.. (2005). Merenje specifične alfa aktivnosti zemlje. in Životna sredina ka Evropi - Simpozijum sa međunarodnim učešćem : Zbornik radova
Beograd : Privredna komora Srbije., 283-286.
https://hdl.handle.net/21.15107/rcub_vinar_12818
Đurašević M, Kandić A, Vukanac I, Obradović Z. Merenje specifične alfa aktivnosti zemlje. in Životna sredina ka Evropi - Simpozijum sa međunarodnim učešćem : Zbornik radova. 2005;:283-286.
https://hdl.handle.net/21.15107/rcub_vinar_12818 .
Đurašević, Mirjana, Kandić, Aleksandar, Vukanac, Ivana, Obradović, Zorica, "Merenje specifične alfa aktivnosti zemlje" in Životna sredina ka Evropi - Simpozijum sa međunarodnim učešćem : Zbornik radova (2005):283-286,
https://hdl.handle.net/21.15107/rcub_vinar_12818 .