TY  - CONF
AU  - Krstić, Danijela
AU  - Lalatović, Jovana
AU  - Mrđa, Davor
AU  - Stojanović, Marko
AU  - Savić, Nada
AU  - Parac-Vogt, Tatjana
AU  - Čolović, Mirjana
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12945
AB  - The purpose of this study was to evaluate in vitro contrast properties of a synthesized Wells-Dawson P2W17O61)2]·19H2O (Hf-WD 1:2), as a potential contrast agent for computed tomography (CT). X-ray attenuation was determined in vitro in the presence of increasing tungsten concentrations (3.125-100 mM) of Hf-WD 1:2. In order to compare the contrast properties of the tungsten-containing Hf-WD 1:2 with a commercially available CT contrast agent that has been used in clinical practice, X-ray attenuation was presented for the same iodine concentrations of iodine-based iohexol solution as well. Higher HU values for particular concentrations were obtained for Hf-WD 1:2 in comparison with those determined for the standard iohexol. Thus, the studied Hf-WD 1:2 POM could be considered a promising contrast agent candidate for CT. Nevertheless, further development of Hf-WD 1:2 as a potential CT contrast requires additional CT studies in vivo and relevant toxicity studies in vitro and in vivo as well.
C3  - International Multidisciplinary Conference "Challenges of Contemporary Higher Education" - CCHE 2024 : Book of proceedings
T1  - Hafnium-containing Wells-Dawson nanocluster as a promising contrast agent candidate
VL  - 2
SP  - 39
EP  - 42
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12945
ER  - 

@conference{
author = "Krstić, Danijela and Lalatović, Jovana and Mrđa, Davor and Stojanović, Marko and Savić, Nada and Parac-Vogt, Tatjana and Čolović, Mirjana",
year = "2024",
abstract = "The purpose of this study was to evaluate in vitro contrast properties of a synthesized Wells-Dawson P2W17O61)2]·19H2O (Hf-WD 1:2), as a potential contrast agent for computed tomography (CT). X-ray attenuation was determined in vitro in the presence of increasing tungsten concentrations (3.125-100 mM) of Hf-WD 1:2. In order to compare the contrast properties of the tungsten-containing Hf-WD 1:2 with a commercially available CT contrast agent that has been used in clinical practice, X-ray attenuation was presented for the same iodine concentrations of iodine-based iohexol solution as well. Higher HU values for particular concentrations were obtained for Hf-WD 1:2 in comparison with those determined for the standard iohexol. Thus, the studied Hf-WD 1:2 POM could be considered a promising contrast agent candidate for CT. Nevertheless, further development of Hf-WD 1:2 as a potential CT contrast requires additional CT studies in vivo and relevant toxicity studies in vitro and in vivo as well.",
journal = "International Multidisciplinary Conference "Challenges of Contemporary Higher Education" - CCHE 2024 : Book of proceedings",
title = "Hafnium-containing Wells-Dawson nanocluster as a promising contrast agent candidate",
volume = "2",
pages = "39-42",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12945"
}

Krstić, D., Lalatović, J., Mrđa, D., Stojanović, M., Savić, N., Parac-Vogt, T.,& Čolović, M.. (2024). Hafnium-containing Wells-Dawson nanocluster as a promising contrast agent candidate. in International Multidisciplinary Conference "Challenges of Contemporary Higher Education" - CCHE 2024 : Book of proceedings, 2, 39-42.
https://hdl.handle.net/21.15107/rcub_vinar_12945

Krstić D, Lalatović J, Mrđa D, Stojanović M, Savić N, Parac-Vogt T, Čolović M. Hafnium-containing Wells-Dawson nanocluster as a promising contrast agent candidate. in International Multidisciplinary Conference "Challenges of Contemporary Higher Education" - CCHE 2024 : Book of proceedings. 2024;2:39-42.
https://hdl.handle.net/21.15107/rcub_vinar_12945 .

Krstić, Danijela, Lalatović, Jovana, Mrđa, Davor, Stojanović, Marko, Savić, Nada, Parac-Vogt, Tatjana, Čolović, Mirjana, "Hafnium-containing Wells-Dawson nanocluster as a promising contrast agent candidate" in International Multidisciplinary Conference "Challenges of Contemporary Higher Education" - CCHE 2024 : Book of proceedings, 2 (2024):39-42,
https://hdl.handle.net/21.15107/rcub_vinar_12945 .

TY  - CONF
AU  - Lalatović, Jovana
AU  - Čolović, Mirjana
AU  - Mrđa, Davor
AU  - Stojanović, Marko
AU  - Krstić, Danijela
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12946
AB  - In this study contrast properties for computed tomography (CT) of two tungstate-containing molecules differing in size, shape, and structure: Keggin type polyoxometalate, 12-tungstosilicic acid, WSiA and sodium tungstate, Na2WO4, were assessed in vitro. In this aim, X-ray attenuation was monitored in vitro at different tungsten concentrations in the range of 3.125-100 mM. A stronger X-ray attenuation was observed for Na2WO4 in the presence of the same tungsten concentrations. In addition, both Na2WO4 and WSiA demonstrated better contrast performance compared to iodine-based iohexol solution, which has been widely applied as a contrast agent for CT. Accordingly, tungsten-containing compounds deserve attention as promising new-generation CT contrast candidates. Thus, future studies should be directed to the synthesis of novel tungsten molecules of different structures resulting in appropriate contrast and low toxicity.
C3  - International Multidisciplinary Conference "Challenges of Contemporary Higher Education" - CCHE 2024 : Book of proceedings
T1  - Tungsten-based molecules of different structure as potential contrast agents
VL  - 2
SP  - 43
EP  - 46
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12946
ER  - 

@conference{
author = "Lalatović, Jovana and Čolović, Mirjana and Mrđa, Davor and Stojanović, Marko and Krstić, Danijela",
year = "2024",
abstract = "In this study contrast properties for computed tomography (CT) of two tungstate-containing molecules differing in size, shape, and structure: Keggin type polyoxometalate, 12-tungstosilicic acid, WSiA and sodium tungstate, Na2WO4, were assessed in vitro. In this aim, X-ray attenuation was monitored in vitro at different tungsten concentrations in the range of 3.125-100 mM. A stronger X-ray attenuation was observed for Na2WO4 in the presence of the same tungsten concentrations. In addition, both Na2WO4 and WSiA demonstrated better contrast performance compared to iodine-based iohexol solution, which has been widely applied as a contrast agent for CT. Accordingly, tungsten-containing compounds deserve attention as promising new-generation CT contrast candidates. Thus, future studies should be directed to the synthesis of novel tungsten molecules of different structures resulting in appropriate contrast and low toxicity.",
journal = "International Multidisciplinary Conference "Challenges of Contemporary Higher Education" - CCHE 2024 : Book of proceedings",
title = "Tungsten-based molecules of different structure as potential contrast agents",
volume = "2",
pages = "43-46",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12946"
}

Lalatović, J., Čolović, M., Mrđa, D., Stojanović, M.,& Krstić, D.. (2024). Tungsten-based molecules of different structure as potential contrast agents. in International Multidisciplinary Conference "Challenges of Contemporary Higher Education" - CCHE 2024 : Book of proceedings, 2, 43-46.
https://hdl.handle.net/21.15107/rcub_vinar_12946

Lalatović J, Čolović M, Mrđa D, Stojanović M, Krstić D. Tungsten-based molecules of different structure as potential contrast agents. in International Multidisciplinary Conference "Challenges of Contemporary Higher Education" - CCHE 2024 : Book of proceedings. 2024;2:43-46.
https://hdl.handle.net/21.15107/rcub_vinar_12946 .

Lalatović, Jovana, Čolović, Mirjana, Mrđa, Davor, Stojanović, Marko, Krstić, Danijela, "Tungsten-based molecules of different structure as potential contrast agents" in International Multidisciplinary Conference "Challenges of Contemporary Higher Education" - CCHE 2024 : Book of proceedings, 2 (2024):43-46,
https://hdl.handle.net/21.15107/rcub_vinar_12946 .