TY  - JOUR
AU  - Dimitrijevic, Dejana P.
AU  - Glodovic, Verica V.
AU  - Radić, Gordana P.
AU  - Garcia-Granda, Santiago
AU  - Menendez-Taboada, Laura
AU  - Milovanović, Marija
AU  - Volarevic, Vladislav
AU  - Arsenijević, Nebojša N.
AU  - Bogdanović, Goran A.
AU  - Trifunović, Srećko R.
PY  - 2013
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/5556
AB  - The synthesis of ethylenediamine-N,N-di-S,S-(2,2-dibenzyl)acetic acid (H-2-S,S-eddba) and its ethyl-, propyl-, butyl-esters (R-2-S,S-eddba) are reported here. The esters were used for synthesis of the corresponding platinum(IV) complexes, [PtCl4(R-2-S,S-eddba)]. The compounds were characterized by elemental analysis, infrared, H-1 and C-13 NMR spectroscopy. The structure of propyl ester of H-2-S,S-eddba was confirmed by single-crystal X-ray analysis. All [PtCl4(R-2-S,S-eddba)] complexes displayed significantly higher in vitro cytotoxicity in comparison to cisplatin. (C) 2013 Published by Elsevier B.V.
T2  - Inorganica Chimica Acta
T1  - Stereospecific ligands and their complexes. Part XV. Synthesis, characterization and cytotoxicity of novel platinum(IV) complexes with some esters of ethylenediamine-N,N -di-S,S-(2,2 -dibenzyl)acetic acid. Crystal structure of O,O -dipropyl-ethylenediamine-N,N -di-S,S-(2,2 -dibenzyl)acetate dihydrochloride
VL  - 402
SP  - 83
EP  - 89
DO  - 10.1016/j.ica.2013.03.039
ER  - 

@article{
author = "Dimitrijevic, Dejana P. and Glodovic, Verica V. and Radić, Gordana P. and Garcia-Granda, Santiago and Menendez-Taboada, Laura and Milovanović, Marija and Volarevic, Vladislav and Arsenijević, Nebojša N. and Bogdanović, Goran A. and Trifunović, Srećko R.",
year = "2013",
abstract = "The synthesis of ethylenediamine-N,N-di-S,S-(2,2-dibenzyl)acetic acid (H-2-S,S-eddba) and its ethyl-, propyl-, butyl-esters (R-2-S,S-eddba) are reported here. The esters were used for synthesis of the corresponding platinum(IV) complexes, [PtCl4(R-2-S,S-eddba)]. The compounds were characterized by elemental analysis, infrared, H-1 and C-13 NMR spectroscopy. The structure of propyl ester of H-2-S,S-eddba was confirmed by single-crystal X-ray analysis. All [PtCl4(R-2-S,S-eddba)] complexes displayed significantly higher in vitro cytotoxicity in comparison to cisplatin. (C) 2013 Published by Elsevier B.V.",
journal = "Inorganica Chimica Acta",
title = "Stereospecific ligands and their complexes. Part XV. Synthesis, characterization and cytotoxicity of novel platinum(IV) complexes with some esters of ethylenediamine-N,N -di-S,S-(2,2 -dibenzyl)acetic acid. Crystal structure of O,O -dipropyl-ethylenediamine-N,N -di-S,S-(2,2 -dibenzyl)acetate dihydrochloride",
volume = "402",
pages = "83-89",
doi = "10.1016/j.ica.2013.03.039"
}

Dimitrijevic, D. P., Glodovic, V. V., Radić, G. P., Garcia-Granda, S., Menendez-Taboada, L., Milovanović, M., Volarevic, V., Arsenijević, N. N., Bogdanović, G. A.,& Trifunović, S. R.. (2013). Stereospecific ligands and their complexes. Part XV. Synthesis, characterization and cytotoxicity of novel platinum(IV) complexes with some esters of ethylenediamine-N,N -di-S,S-(2,2 -dibenzyl)acetic acid. Crystal structure of O,O -dipropyl-ethylenediamine-N,N -di-S,S-(2,2 -dibenzyl)acetate dihydrochloride. in Inorganica Chimica Acta, 402, 83-89.
https://doi.org/10.1016/j.ica.2013.03.039

Dimitrijevic DP, Glodovic VV, Radić GP, Garcia-Granda S, Menendez-Taboada L, Milovanović M, Volarevic V, Arsenijević NN, Bogdanović GA, Trifunović SR. Stereospecific ligands and their complexes. Part XV. Synthesis, characterization and cytotoxicity of novel platinum(IV) complexes with some esters of ethylenediamine-N,N -di-S,S-(2,2 -dibenzyl)acetic acid. Crystal structure of O,O -dipropyl-ethylenediamine-N,N -di-S,S-(2,2 -dibenzyl)acetate dihydrochloride. in Inorganica Chimica Acta. 2013;402:83-89.
doi:10.1016/j.ica.2013.03.039 .

Dimitrijevic, Dejana P., Glodovic, Verica V., Radić, Gordana P., Garcia-Granda, Santiago, Menendez-Taboada, Laura, Milovanović, Marija, Volarevic, Vladislav, Arsenijević, Nebojša N., Bogdanović, Goran A., Trifunović, Srećko R., "Stereospecific ligands and their complexes. Part XV. Synthesis, characterization and cytotoxicity of novel platinum(IV) complexes with some esters of ethylenediamine-N,N -di-S,S-(2,2 -dibenzyl)acetic acid. Crystal structure of O,O -dipropyl-ethylenediamine-N,N -di-S,S-(2,2 -dibenzyl)acetate dihydrochloride" in Inorganica Chimica Acta, 402 (2013):83-89,
https://doi.org/10.1016/j.ica.2013.03.039 . .

TY  - JOUR
AU  - Radić, Gordana P.
AU  - Glodovic, Verica V.
AU  - Ratković, Zoran R.
AU  - Novaković, Slađana B.
AU  - Garcia-Granda, Santiago
AU  - Roces, Laura
AU  - Menendez-Taboada, Laura
AU  - Radojevic, Ivana D.
AU  - Stefanovic, Olgica D.
AU  - Čomić, Ljiljana R.
AU  - Trifunović, Srećko R.
PY  - 2012
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/5197
AB  - In the reaction of meso-1,2-diphenyl-ethylenediamine (1,2-dphen) with neutralized 3-chlor-propanoic acid, the new linear tetradentate edda-like ligand (edda = ethylenediamine-N,N-diacetic ion) meso-1, 2-diphenyl-ethylenediamine-N,N-di-3-propanoic acid dihydrochloride monohydrate (H-2-1,2-dpheddp center dot 2HCl center dot H2O) was prepared. The corresponding platinum(IV) complex, s-cis-dichlorido-(meso-1,2-diphenyl-ethylenediamine-N,N-di-3-propanoate)-platinum(IV) ([PtCl2(1,2-dpheddp)]) was synthesized by heating potassium-hexachloridoplatinate(IV) and H-2-1,2-dpheddp center dot 2HCl center dot H2O on steam bath for 12 h with neutralization by means of lithium-hydroxide. The palladium(II) complex, cis-dichlorido-(meso-1,2diphenyl-ethylenediamine-N,N-di-3-propanoate)-palladium(II) (IPdCl2(1,2-dpheddp)]) was obtained in the similar way using potassium-tetrachloridopalladate(II), H-2-1,2-dpheddp-2HCl center dot H2O and lithium-hydroxide. The compounds were characterized by elemental analysis and infrared spectroscopy. The spectroscopically predicted structure of the synthesized tetradentate ligand was confirmed by X-ray analysis of the H-2-1,2-dpheddp.2HCl center dot H2O. Antimicrobial activity of the ligand and corresponding palladium(II) and platinum(IV) complexes is investigated against 25 species of microorganisms. Testing is preformed by microdilution method and minimum inhibitory concentrations (MIC) and minimum microbicidal concentration (MMC) have been determined. The difference between antimicrobial activity of the ligand and corresponding platinum(IV) and palladium(II) complex is noticed and, in general, palladium(II) complex was the most active. (C) 2012 Elsevier B.V. All rights reserved.
T2  - Journal of Molecular Structure
T1  - Synthesis, characterization and antimicrobial activity of novel platinum(IV) and palladium(II) complexes with meso-1,2-diphenyl-ethylenediamine-N,N -di-3-propanoic acid - Crystal structure of H-2-1,2-dpheddp center dot 2HCl center dot H2O
VL  - 1029
SP  - 180
EP  - 186
DO  - 10.1016/j.molstruc.2012.07.007
ER  - 

@article{
author = "Radić, Gordana P. and Glodovic, Verica V. and Ratković, Zoran R. and Novaković, Slađana B. and Garcia-Granda, Santiago and Roces, Laura and Menendez-Taboada, Laura and Radojevic, Ivana D. and Stefanovic, Olgica D. and Čomić, Ljiljana R. and Trifunović, Srećko R.",
year = "2012",
abstract = "In the reaction of meso-1,2-diphenyl-ethylenediamine (1,2-dphen) with neutralized 3-chlor-propanoic acid, the new linear tetradentate edda-like ligand (edda = ethylenediamine-N,N-diacetic ion) meso-1, 2-diphenyl-ethylenediamine-N,N-di-3-propanoic acid dihydrochloride monohydrate (H-2-1,2-dpheddp center dot 2HCl center dot H2O) was prepared. The corresponding platinum(IV) complex, s-cis-dichlorido-(meso-1,2-diphenyl-ethylenediamine-N,N-di-3-propanoate)-platinum(IV) ([PtCl2(1,2-dpheddp)]) was synthesized by heating potassium-hexachloridoplatinate(IV) and H-2-1,2-dpheddp center dot 2HCl center dot H2O on steam bath for 12 h with neutralization by means of lithium-hydroxide. The palladium(II) complex, cis-dichlorido-(meso-1,2diphenyl-ethylenediamine-N,N-di-3-propanoate)-palladium(II) (IPdCl2(1,2-dpheddp)]) was obtained in the similar way using potassium-tetrachloridopalladate(II), H-2-1,2-dpheddp-2HCl center dot H2O and lithium-hydroxide. The compounds were characterized by elemental analysis and infrared spectroscopy. The spectroscopically predicted structure of the synthesized tetradentate ligand was confirmed by X-ray analysis of the H-2-1,2-dpheddp.2HCl center dot H2O. Antimicrobial activity of the ligand and corresponding palladium(II) and platinum(IV) complexes is investigated against 25 species of microorganisms. Testing is preformed by microdilution method and minimum inhibitory concentrations (MIC) and minimum microbicidal concentration (MMC) have been determined. The difference between antimicrobial activity of the ligand and corresponding platinum(IV) and palladium(II) complex is noticed and, in general, palladium(II) complex was the most active. (C) 2012 Elsevier B.V. All rights reserved.",
journal = "Journal of Molecular Structure",
title = "Synthesis, characterization and antimicrobial activity of novel platinum(IV) and palladium(II) complexes with meso-1,2-diphenyl-ethylenediamine-N,N -di-3-propanoic acid - Crystal structure of H-2-1,2-dpheddp center dot 2HCl center dot H2O",
volume = "1029",
pages = "180-186",
doi = "10.1016/j.molstruc.2012.07.007"
}

Radić, G. P., Glodovic, V. V., Ratković, Z. R., Novaković, S. B., Garcia-Granda, S., Roces, L., Menendez-Taboada, L., Radojevic, I. D., Stefanovic, O. D., Čomić, L. R.,& Trifunović, S. R.. (2012). Synthesis, characterization and antimicrobial activity of novel platinum(IV) and palladium(II) complexes with meso-1,2-diphenyl-ethylenediamine-N,N -di-3-propanoic acid - Crystal structure of H-2-1,2-dpheddp center dot 2HCl center dot H2O. in Journal of Molecular Structure, 1029, 180-186.
https://doi.org/10.1016/j.molstruc.2012.07.007

Radić GP, Glodovic VV, Ratković ZR, Novaković SB, Garcia-Granda S, Roces L, Menendez-Taboada L, Radojevic ID, Stefanovic OD, Čomić LR, Trifunović SR. Synthesis, characterization and antimicrobial activity of novel platinum(IV) and palladium(II) complexes with meso-1,2-diphenyl-ethylenediamine-N,N -di-3-propanoic acid - Crystal structure of H-2-1,2-dpheddp center dot 2HCl center dot H2O. in Journal of Molecular Structure. 2012;1029:180-186.
doi:10.1016/j.molstruc.2012.07.007 .

Radić, Gordana P., Glodovic, Verica V., Ratković, Zoran R., Novaković, Slađana B., Garcia-Granda, Santiago, Roces, Laura, Menendez-Taboada, Laura, Radojevic, Ivana D., Stefanovic, Olgica D., Čomić, Ljiljana R., Trifunović, Srećko R., "Synthesis, characterization and antimicrobial activity of novel platinum(IV) and palladium(II) complexes with meso-1,2-diphenyl-ethylenediamine-N,N -di-3-propanoic acid - Crystal structure of H-2-1,2-dpheddp center dot 2HCl center dot H2O" in Journal of Molecular Structure, 1029 (2012):180-186,
https://doi.org/10.1016/j.molstruc.2012.07.007 . .