TY  - CONF
AU  - Orlovska, Iryna
AU  - Zmejkoski, Danica
AU  - Khirunenko, L.
AU  - Kozyrovska, N.
PY  - 2017
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/13008
AB  - Biofilm-forming multi-drug resistant pathogens may account for 10% of all hospital acquired infections and can occur in burns, post-surgical wounds, pressure injuries and diabetic foot wounds. Hydrogels – natural polymers or composite materials – represent both a bandage and a matrix for therapeutics in a wound healing. Novel composite based on bacterial cellulose and synthetic analog of lignin - DHP (dehydrogenate polymer) has been designed with the aim to suppress pathogenic agents in incurable wounds. The FT-IR spectra of the BC/DHP membrane established an appearance of characteristic for DHP absorption bands in the composite in the 1600–1510 cm−1 spectral range. A clear position of these bands in BC/DHP showed that DHP had been incorporated into the BC polymeric matrix. In addition, disappearance of the bands at the 3630–3650 cm−1 spectral range assigned to the cellulose free OH vibration, strengthening the bands assigned to intermolecular interactions and an appearance of a new band at 3293 cm−1 could serve as a proof of the interaction of BC molecules and DHP. Micrographs obtained from a scanning electron microscopy proved the dose-dependent interaction of DHP with BC, which resulted in a decrease of the pore number in the cellulose membrane. The antimicrobial activity of composites BC/DHP were tested the in vitro experiments, using Pseudomonas aeruginosa (УМВ-100) (MTT-test) and showed that BC/DHP inhibited P. aeruginosa. BC/DHP composite will be promising hydrogel for a healing of infected incurable wounds.
C3  - Integrative Biology & Medicine : Program and Abstracts
T1  - A composite of bacterial cellulose and lignin for a healing of incurable wounds
SP  - 53
EP  - 53
UR  - https://hdl.handle.net/21.15107/rcub_vinar_13008
ER  - 

@conference{
author = "Orlovska, Iryna and Zmejkoski, Danica and Khirunenko, L. and Kozyrovska, N.",
year = "2017",
abstract = "Biofilm-forming multi-drug resistant pathogens may account for 10% of all hospital acquired infections and can occur in burns, post-surgical wounds, pressure injuries and diabetic foot wounds. Hydrogels – natural polymers or composite materials – represent both a bandage and a matrix for therapeutics in a wound healing. Novel composite based on bacterial cellulose and synthetic analog of lignin - DHP (dehydrogenate polymer) has been designed with the aim to suppress pathogenic agents in incurable wounds. The FT-IR spectra of the BC/DHP membrane established an appearance of characteristic for DHP absorption bands in the composite in the 1600–1510 cm−1 spectral range. A clear position of these bands in BC/DHP showed that DHP had been incorporated into the BC polymeric matrix. In addition, disappearance of the bands at the 3630–3650 cm−1 spectral range assigned to the cellulose free OH vibration, strengthening the bands assigned to intermolecular interactions and an appearance of a new band at 3293 cm−1 could serve as a proof of the interaction of BC molecules and DHP. Micrographs obtained from a scanning electron microscopy proved the dose-dependent interaction of DHP with BC, which resulted in a decrease of the pore number in the cellulose membrane. The antimicrobial activity of composites BC/DHP were tested the in vitro experiments, using Pseudomonas aeruginosa (УМВ-100) (MTT-test) and showed that BC/DHP inhibited P. aeruginosa. BC/DHP composite will be promising hydrogel for a healing of infected incurable wounds.",
journal = "Integrative Biology & Medicine : Program and Abstracts",
title = "A composite of bacterial cellulose and lignin for a healing of incurable wounds",
pages = "53-53",
url = "https://hdl.handle.net/21.15107/rcub_vinar_13008"
}

Orlovska, I., Zmejkoski, D., Khirunenko, L.,& Kozyrovska, N.. (2017). A composite of bacterial cellulose and lignin for a healing of incurable wounds. in Integrative Biology & Medicine : Program and Abstracts, 53-53.
https://hdl.handle.net/21.15107/rcub_vinar_13008

Orlovska I, Zmejkoski D, Khirunenko L, Kozyrovska N. A composite of bacterial cellulose and lignin for a healing of incurable wounds. in Integrative Biology & Medicine : Program and Abstracts. 2017;:53-53.
https://hdl.handle.net/21.15107/rcub_vinar_13008 .

Orlovska, Iryna, Zmejkoski, Danica, Khirunenko, L., Kozyrovska, N., "A composite of bacterial cellulose and lignin for a healing of incurable wounds" in Integrative Biology & Medicine : Program and Abstracts (2017):53-53,
https://hdl.handle.net/21.15107/rcub_vinar_13008 .