TY  - CONF
AU  - Ilić, Jana
AU  - Trišić, Dijana
AU  - Čolović, Božana
AU  - Ilić, Bojana
AU  - Filipović Tričković, Jelena
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12812
AB  - Aim: The use of nitinol archwires (NiTi) in orthodontic treatment has expanded significantly due to unique
mechanical properties such as shape memory effect and superelasticity. The greatest barrier to safe
application of NiTi archwires is microbiologically or electrochemically induced corrosion. Corrosion of NiTi
archwires result in Ni2+ release, leading to different health implications. The purpose of this investigation is
the improvement of NiTi archwires properties by synthesis of multilayerd, firmly bonded nanocoatings with
antibacterial properties using the magnetron sputtering (MS). These nanocoatings will enhance corrosion
resistance and decrease cytotoxic properties by preventing Ni2+ release, without compromising mechanical
characteristics of the conventional NiTi archwires. Materials and Method: The nanocoatings of TiO2, TiN,
TiN+Cu were acquired by pulsed magnetron sputtering using the commercially available nickel-titanium
archwires. The samples were assessed using atomic force microscopy and X-ray diffraction. Inductively
coupled plasma - optical emission spectrometry was used to estimate the release of Ni, Ti, Cu, Fe, Cr, Zn
ions into DMEM and acidic solution. Biocompatibility of samples' eluates was investigated using Neutral red
staining. Disk Diffusion Method was used for assessing the antibacterial properties against bacterial
suspensions of Streptococcus mutans. Results: Compared to NiTi and stainless steel, the nonocoated
archwires showed statistically lower release of nickel both in DMEM and acidic environment (p<0.05).
Regarding the relative cell viability, the 7-day eluates of nanocoated archwires was the highest (p<0.05).
Antibacterial activity of nanocoated archwires was statistically significant in comparison to the conventional
NiTi and stainless steel archwires (p<0.05). Conclusions: As nanocoated archwires presented desired
antibacterial properties with better stability in both acidic and non-acidic conditions, as well as satisfactory biocompatibility, they may be a good candidate for further clinical investigations.
PB  - European Orthodontic Society
C3  - European Journal of Orthodontics
T1  - Novel Nanocoated Nitinol Archwires With Antibacterial Properties
VL  - 45
IS  - 6 - EOS2023 Abstracts
SP  - e162
EP  - e162
DO  - 10.1093/ejo/cjad072
ER  - 

@conference{
author = "Ilić, Jana and Trišić, Dijana and Čolović, Božana and Ilić, Bojana and Filipović Tričković, Jelena",
year = "2023",
abstract = "Aim: The use of nitinol archwires (NiTi) in orthodontic treatment has expanded significantly due to unique
mechanical properties such as shape memory effect and superelasticity. The greatest barrier to safe
application of NiTi archwires is microbiologically or electrochemically induced corrosion. Corrosion of NiTi
archwires result in Ni2+ release, leading to different health implications. The purpose of this investigation is
the improvement of NiTi archwires properties by synthesis of multilayerd, firmly bonded nanocoatings with
antibacterial properties using the magnetron sputtering (MS). These nanocoatings will enhance corrosion
resistance and decrease cytotoxic properties by preventing Ni2+ release, without compromising mechanical
characteristics of the conventional NiTi archwires. Materials and Method: The nanocoatings of TiO2, TiN,
TiN+Cu were acquired by pulsed magnetron sputtering using the commercially available nickel-titanium
archwires. The samples were assessed using atomic force microscopy and X-ray diffraction. Inductively
coupled plasma - optical emission spectrometry was used to estimate the release of Ni, Ti, Cu, Fe, Cr, Zn
ions into DMEM and acidic solution. Biocompatibility of samples' eluates was investigated using Neutral red
staining. Disk Diffusion Method was used for assessing the antibacterial properties against bacterial
suspensions of Streptococcus mutans. Results: Compared to NiTi and stainless steel, the nonocoated
archwires showed statistically lower release of nickel both in DMEM and acidic environment (p<0.05).
Regarding the relative cell viability, the 7-day eluates of nanocoated archwires was the highest (p<0.05).
Antibacterial activity of nanocoated archwires was statistically significant in comparison to the conventional
NiTi and stainless steel archwires (p<0.05). Conclusions: As nanocoated archwires presented desired
antibacterial properties with better stability in both acidic and non-acidic conditions, as well as satisfactory biocompatibility, they may be a good candidate for further clinical investigations.",
publisher = "European Orthodontic Society",
journal = "European Journal of Orthodontics",
title = "Novel Nanocoated Nitinol Archwires With Antibacterial Properties",
volume = "45",
number = "6 - EOS2023 Abstracts",
pages = "e162-e162",
doi = "10.1093/ejo/cjad072"
}

Ilić, J., Trišić, D., Čolović, B., Ilić, B.,& Filipović Tričković, J.. (2023). Novel Nanocoated Nitinol Archwires With Antibacterial Properties. in European Journal of Orthodontics
European Orthodontic Society., 45(6 - EOS2023 Abstracts), e162-e162.
https://doi.org/10.1093/ejo/cjad072

Ilić J, Trišić D, Čolović B, Ilić B, Filipović Tričković J. Novel Nanocoated Nitinol Archwires With Antibacterial Properties. in European Journal of Orthodontics. 2023;45(6 - EOS2023 Abstracts):e162-e162.
doi:10.1093/ejo/cjad072 .

Ilić, Jana, Trišić, Dijana, Čolović, Božana, Ilić, Bojana, Filipović Tričković, Jelena, "Novel Nanocoated Nitinol Archwires With Antibacterial Properties" in European Journal of Orthodontics, 45, no. 6 - EOS2023 Abstracts (2023):e162-e162,
https://doi.org/10.1093/ejo/cjad072 . .