TY  - JOUR
AU  - Suljovrujić, Edin H.
AU  - Krstić, Maja
AU  - Rogić Miladinović, Zorana
AU  - Petrović, Sandra
AU  - Leskovac, Andreja
AU  - Stamboliev, Georgi
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/11063
AB  - Hydrogels with oligo(ethylene glycol) (OEG), oligo(propylene glycol) (OPG), and for the first time with combined OEG/OPG pendant chains within the methacrylate (MA) network, were synthesized and the swelling behavior, thermal properties, microstructure, and genotoxicity were investigated. Prior to hydrogel fabrication, an optimized method was developed for oligo(propylene glycol) methacrylate (OPGMA), i.e., oligomer with an LCST below a temperature at which synthesis occurs, indicating that proper preparation and tuning of reaction conditions were required. PEG6MA and PPG5MA homopolymers, as well as P(EG6/PG5)MA copolymer hydrogel, were produced by gamma radiation-induced polymerization and crosslinking of OEG and OPG monomers from the monomer-solvent mixture by using different water/ethanol composition as a solvent and by exposing the reaction mixture to various radiation doses. The combination of OEG and OPG pendant chains within the same network was advantageous in that it allowed an easy tuning of the phase transition temperature. Thus, the volume phase transition (VPT) at temperatures above 70 °C observed in the case of PEG6MA, and in the case of PPG5MA at temperatures below 15 °C, could easily be tuned close to physiological temperatures for P(EG6/PG5)MA hydrogel. Finally, all obtained thermoresponsive hydrogels showed non-genotoxic and non-cytotoxic properties, which indicate promising potential for biomedical applications.
T2  - Reactive and Functional Polymers
T1  - Optimization of thermoresponsive hydrogels based on oligomers with lower critical solution temperature (LCST) far below/above physiological temperatures for biomedical applications
VL  - 189
SP  - 105612
DO  - 10.1016/j.reactfunctpolym.2023.105612
ER  - 

@article{
author = "Suljovrujić, Edin H. and Krstić, Maja and Rogić Miladinović, Zorana and Petrović, Sandra and Leskovac, Andreja and Stamboliev, Georgi",
year = "2023",
abstract = "Hydrogels with oligo(ethylene glycol) (OEG), oligo(propylene glycol) (OPG), and for the first time with combined OEG/OPG pendant chains within the methacrylate (MA) network, were synthesized and the swelling behavior, thermal properties, microstructure, and genotoxicity were investigated. Prior to hydrogel fabrication, an optimized method was developed for oligo(propylene glycol) methacrylate (OPGMA), i.e., oligomer with an LCST below a temperature at which synthesis occurs, indicating that proper preparation and tuning of reaction conditions were required. PEG6MA and PPG5MA homopolymers, as well as P(EG6/PG5)MA copolymer hydrogel, were produced by gamma radiation-induced polymerization and crosslinking of OEG and OPG monomers from the monomer-solvent mixture by using different water/ethanol composition as a solvent and by exposing the reaction mixture to various radiation doses. The combination of OEG and OPG pendant chains within the same network was advantageous in that it allowed an easy tuning of the phase transition temperature. Thus, the volume phase transition (VPT) at temperatures above 70 °C observed in the case of PEG6MA, and in the case of PPG5MA at temperatures below 15 °C, could easily be tuned close to physiological temperatures for P(EG6/PG5)MA hydrogel. Finally, all obtained thermoresponsive hydrogels showed non-genotoxic and non-cytotoxic properties, which indicate promising potential for biomedical applications.",
journal = "Reactive and Functional Polymers",
title = "Optimization of thermoresponsive hydrogels based on oligomers with lower critical solution temperature (LCST) far below/above physiological temperatures for biomedical applications",
volume = "189",
pages = "105612",
doi = "10.1016/j.reactfunctpolym.2023.105612"
}

Suljovrujić, E. H., Krstić, M., Rogić Miladinović, Z., Petrović, S., Leskovac, A.,& Stamboliev, G.. (2023). Optimization of thermoresponsive hydrogels based on oligomers with lower critical solution temperature (LCST) far below/above physiological temperatures for biomedical applications. in Reactive and Functional Polymers, 189, 105612.
https://doi.org/10.1016/j.reactfunctpolym.2023.105612

Suljovrujić EH, Krstić M, Rogić Miladinović Z, Petrović S, Leskovac A, Stamboliev G. Optimization of thermoresponsive hydrogels based on oligomers with lower critical solution temperature (LCST) far below/above physiological temperatures for biomedical applications. in Reactive and Functional Polymers. 2023;189:105612.
doi:10.1016/j.reactfunctpolym.2023.105612 .

Suljovrujić, Edin H., Krstić, Maja, Rogić Miladinović, Zorana, Petrović, Sandra, Leskovac, Andreja, Stamboliev, Georgi, "Optimization of thermoresponsive hydrogels based on oligomers with lower critical solution temperature (LCST) far below/above physiological temperatures for biomedical applications" in Reactive and Functional Polymers, 189 (2023):105612,
https://doi.org/10.1016/j.reactfunctpolym.2023.105612 . .

TY  - JOUR
AU  - Stamboliev, Georgi
AU  - Miličević, Dejan S.
AU  - Mićić, Maja M.
AU  - Suljovrujić, Edin H.
PY  - 2015
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/388
AB  - Changes in the structure and dielectric properties of low-density polyethylene were created by gamma irradiation in air, deionised water and nitrogen. Role of irradiation media on dielectric and charge trapping behaviour was studied through dielectric loss and thermally stimulated discharge current measurements. Changes in magnitude, position and activation energy of all dielectric relaxations (gamma, beta and alpha) were found to be dependent on crosslinking and oxidative degradation, two competitive processes which can be tuned by radiation dose and media. Largest changes in the position and activation energy were found for the beta relaxation due to its cooperative nature.
T2  - Polymer Bulletin
T1  - Polyethylene crosslinked in different media: structural changes versus dielectric behaviour
VL  - 72
IS  - 2
SP  - 371
EP  - 385
DO  - 10.1007/s00289-014-1279-y
ER  - 

@article{
author = "Stamboliev, Georgi and Miličević, Dejan S. and Mićić, Maja M. and Suljovrujić, Edin H.",
year = "2015",
abstract = "Changes in the structure and dielectric properties of low-density polyethylene were created by gamma irradiation in air, deionised water and nitrogen. Role of irradiation media on dielectric and charge trapping behaviour was studied through dielectric loss and thermally stimulated discharge current measurements. Changes in magnitude, position and activation energy of all dielectric relaxations (gamma, beta and alpha) were found to be dependent on crosslinking and oxidative degradation, two competitive processes which can be tuned by radiation dose and media. Largest changes in the position and activation energy were found for the beta relaxation due to its cooperative nature.",
journal = "Polymer Bulletin",
title = "Polyethylene crosslinked in different media: structural changes versus dielectric behaviour",
volume = "72",
number = "2",
pages = "371-385",
doi = "10.1007/s00289-014-1279-y"
}

Stamboliev, G., Miličević, D. S., Mićić, M. M.,& Suljovrujić, E. H.. (2015). Polyethylene crosslinked in different media: structural changes versus dielectric behaviour. in Polymer Bulletin, 72(2), 371-385.
https://doi.org/10.1007/s00289-014-1279-y

Stamboliev G, Miličević DS, Mićić MM, Suljovrujić EH. Polyethylene crosslinked in different media: structural changes versus dielectric behaviour. in Polymer Bulletin. 2015;72(2):371-385.
doi:10.1007/s00289-014-1279-y .

Stamboliev, Georgi, Miličević, Dejan S., Mićić, Maja M., Suljovrujić, Edin H., "Polyethylene crosslinked in different media: structural changes versus dielectric behaviour" in Polymer Bulletin, 72, no. 2 (2015):371-385,
https://doi.org/10.1007/s00289-014-1279-y . .