TY  - JOUR
AU  - Seke, Mariana
AU  - Markelić, Milica
AU  - Morina, Arian
AU  - Jović, Danica S.
AU  - Korać, Aleksandra
AU  - Miličić, Dragana
AU  - Đorđević, Aleksandar N.
PY  - 2017
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/1609
AB  - Adsorption of non-polar compounds by suspended fullerene nanoaggregates (nC(60)) may enhance their toxicity and affect the fate, transformation, and transport of non-polar compounds in the environment. The potential of stable fullerene nanoaggregates as contaminant carriers in aqueous systems and the influence of chloromethanes (trichloromethane and dichloromethane) were studied on the midgut epithelial cells of Daphnia magna by light and electron microscopy. The size and shape of fullerene nanoaggregates were observed and measured using dynamic light scattering, transmission electron microscopy, and low vacuum scanning electron microscopy. The nC(60) in suspension appeared as a bulk of aggregates of irregular shape with a surface consisting of small clumps 20-30 nm in diameter. The presence of nC(60) aggregates was confirmed in midgut lumen and epithelial cells of D. magna. After in vivo acute exposure to chloromethane, light and electron microscopy revealed an extensive cytoplasmic vacuolization with disruption and loss of specific structures of D. magna midgut epithelium (mitochondria, endoplasmic reticulum, microvilli, peritrophic membrane) and increased appearance of necrotic cells. The degree of observed changes depended on the type of treatment: trichloromethane (TCM) induced the most notable changes, whereas fullerene nanoaggregates alone had no negative effects. Transmission electron microscopy also indicated increased lysosomal degradation and severe peroxidative damages of enterocyte mitochondria following combined exposure to chloromethane and fullerene nanoaggregates. In conclusion, the adsorption of chloromethane by fullerene nanoaggregates enhances their toxicity and induces peroxidative mitochondrial damage in midgut enterocytes.
T2  - Protoplasma
T1  - Synergistic mitotoxicity of chloromethanes and fullerene C-60 nanoaggregates in Daphnia magna midgut epithelial cells
VL  - 254
IS  - 4
SP  - 1607
EP  - 1616
DO  - 10.1007/s00709-016-1049-9
ER  - 

@article{
author = "Seke, Mariana and Markelić, Milica and Morina, Arian and Jović, Danica S. and Korać, Aleksandra and Miličić, Dragana and Đorđević, Aleksandar N.",
year = "2017",
abstract = "Adsorption of non-polar compounds by suspended fullerene nanoaggregates (nC(60)) may enhance their toxicity and affect the fate, transformation, and transport of non-polar compounds in the environment. The potential of stable fullerene nanoaggregates as contaminant carriers in aqueous systems and the influence of chloromethanes (trichloromethane and dichloromethane) were studied on the midgut epithelial cells of Daphnia magna by light and electron microscopy. The size and shape of fullerene nanoaggregates were observed and measured using dynamic light scattering, transmission electron microscopy, and low vacuum scanning electron microscopy. The nC(60) in suspension appeared as a bulk of aggregates of irregular shape with a surface consisting of small clumps 20-30 nm in diameter. The presence of nC(60) aggregates was confirmed in midgut lumen and epithelial cells of D. magna. After in vivo acute exposure to chloromethane, light and electron microscopy revealed an extensive cytoplasmic vacuolization with disruption and loss of specific structures of D. magna midgut epithelium (mitochondria, endoplasmic reticulum, microvilli, peritrophic membrane) and increased appearance of necrotic cells. The degree of observed changes depended on the type of treatment: trichloromethane (TCM) induced the most notable changes, whereas fullerene nanoaggregates alone had no negative effects. Transmission electron microscopy also indicated increased lysosomal degradation and severe peroxidative damages of enterocyte mitochondria following combined exposure to chloromethane and fullerene nanoaggregates. In conclusion, the adsorption of chloromethane by fullerene nanoaggregates enhances their toxicity and induces peroxidative mitochondrial damage in midgut enterocytes.",
journal = "Protoplasma",
title = "Synergistic mitotoxicity of chloromethanes and fullerene C-60 nanoaggregates in Daphnia magna midgut epithelial cells",
volume = "254",
number = "4",
pages = "1607-1616",
doi = "10.1007/s00709-016-1049-9"
}

Seke, M., Markelić, M., Morina, A., Jović, D. S., Korać, A., Miličić, D.,& Đorđević, A. N.. (2017). Synergistic mitotoxicity of chloromethanes and fullerene C-60 nanoaggregates in Daphnia magna midgut epithelial cells. in Protoplasma, 254(4), 1607-1616.
https://doi.org/10.1007/s00709-016-1049-9

Seke M, Markelić M, Morina A, Jović DS, Korać A, Miličić D, Đorđević AN. Synergistic mitotoxicity of chloromethanes and fullerene C-60 nanoaggregates in Daphnia magna midgut epithelial cells. in Protoplasma. 2017;254(4):1607-1616.
doi:10.1007/s00709-016-1049-9 .

Seke, Mariana, Markelić, Milica, Morina, Arian, Jović, Danica S., Korać, Aleksandra, Miličić, Dragana, Đorđević, Aleksandar N., "Synergistic mitotoxicity of chloromethanes and fullerene C-60 nanoaggregates in Daphnia magna midgut epithelial cells" in Protoplasma, 254, no. 4 (2017):1607-1616,
https://doi.org/10.1007/s00709-016-1049-9 . .

TY  - CONF
AU  - Miličić, Dragana
AU  - Jokic, Ljiljana
AU  - Blagdanic, Sanja
AU  - Jokić, Stevan
PY  - 2016
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/7100
AB  - With this article we would like to stress science teachers must doing practical work and communicate on the basis of scientific knowledge and developments, but also allow their students opportunity to discover knowledge through inquiry. During the last five years Serbian project Ruka u testu (semi-mirror of the French project La main a la pate), as well as European FIBONACCI and SUSTAIN projects have offered to our teachers the wide-scale learning opportunities based on Inquiry Based Science Education (IBSE) and Education for Sustainable Development (ESD). Our current efforts are based on pedagogical guidance, several modules and experimental kits, the website, exhibitions, and trainings and workshops for students and teachers.
C3  - AIP Conference Proceedings
T1  - Education for Sustainable Development - Resources for Physics and Sciences Teachers
VL  - 1722
DO  - 10.1063/1.4944121
ER  - 

@conference{
author = "Miličić, Dragana and Jokic, Ljiljana and Blagdanic, Sanja and Jokić, Stevan",
year = "2016",
abstract = "With this article we would like to stress science teachers must doing practical work and communicate on the basis of scientific knowledge and developments, but also allow their students opportunity to discover knowledge through inquiry. During the last five years Serbian project Ruka u testu (semi-mirror of the French project La main a la pate), as well as European FIBONACCI and SUSTAIN projects have offered to our teachers the wide-scale learning opportunities based on Inquiry Based Science Education (IBSE) and Education for Sustainable Development (ESD). Our current efforts are based on pedagogical guidance, several modules and experimental kits, the website, exhibitions, and trainings and workshops for students and teachers.",
journal = "AIP Conference Proceedings",
title = "Education for Sustainable Development - Resources for Physics and Sciences Teachers",
volume = "1722",
doi = "10.1063/1.4944121"
}

Miličić, D., Jokic, L., Blagdanic, S.,& Jokić, S.. (2016). Education for Sustainable Development - Resources for Physics and Sciences Teachers. in AIP Conference Proceedings, 1722.
https://doi.org/10.1063/1.4944121

Miličić D, Jokic L, Blagdanic S, Jokić S. Education for Sustainable Development - Resources for Physics and Sciences Teachers. in AIP Conference Proceedings. 2016;1722.
doi:10.1063/1.4944121 .

Miličić, Dragana, Jokic, Ljiljana, Blagdanic, Sanja, Jokić, Stevan, "Education for Sustainable Development - Resources for Physics and Sciences Teachers" in AIP Conference Proceedings, 1722 (2016),
https://doi.org/10.1063/1.4944121 . .

TY  - JOUR
AU  - Miličić, Dragana
AU  - Karan-Znidarsic, Tamara
AU  - Pavković-Lučić, Sofija
AU  - Lucic, Luka
AU  - Jokić, Stevan
PY  - 2010
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2735
AB  - The project Hands on has being implemented in Serbia since 2001 in order to uplift and revitalize teaching of the natural sciences in Primary Schools and enhance a personal engagement by the pupils in different topics. In 2003, the Serbian Ministry of Education decided to put forward an optional course Hands on - Discovering the World, for children from 6 to 8 years old. Resources related to the biology have been occurred through seven modules, as follows: Plants, Food and digestion, Five senses, Growing and aging, Ecosystems, Environment. Knowing that topics in systematic biology are usually considered difficult and demanding, here we present the new, interesting, simple and creative way to teach systematics and classification since the early age, based on the Hands on method. New module refers to the classification of living beings, when teachers encourage their pupils to observe similar attributes, arrange the hierarchy of nested groups and classify animals discovering the evolutionary relationships of taxa.
T2  - Biotechnology and Biotechnological Equipment
T1  - Teaching in Biological Sciences At Primary Schools in Serbia - An Application of the Hands on Method
VL  - 24
IS  - 2
SP  - 306
EP  - 310
DO  - 10.1080/13102818.2010.10817852
ER  - 

@article{
author = "Miličić, Dragana and Karan-Znidarsic, Tamara and Pavković-Lučić, Sofija and Lucic, Luka and Jokić, Stevan",
year = "2010",
abstract = "The project Hands on has being implemented in Serbia since 2001 in order to uplift and revitalize teaching of the natural sciences in Primary Schools and enhance a personal engagement by the pupils in different topics. In 2003, the Serbian Ministry of Education decided to put forward an optional course Hands on - Discovering the World, for children from 6 to 8 years old. Resources related to the biology have been occurred through seven modules, as follows: Plants, Food and digestion, Five senses, Growing and aging, Ecosystems, Environment. Knowing that topics in systematic biology are usually considered difficult and demanding, here we present the new, interesting, simple and creative way to teach systematics and classification since the early age, based on the Hands on method. New module refers to the classification of living beings, when teachers encourage their pupils to observe similar attributes, arrange the hierarchy of nested groups and classify animals discovering the evolutionary relationships of taxa.",
journal = "Biotechnology and Biotechnological Equipment",
title = "Teaching in Biological Sciences At Primary Schools in Serbia - An Application of the Hands on Method",
volume = "24",
number = "2",
pages = "306-310",
doi = "10.1080/13102818.2010.10817852"
}

Miličić, D., Karan-Znidarsic, T., Pavković-Lučić, S., Lucic, L.,& Jokić, S.. (2010). Teaching in Biological Sciences At Primary Schools in Serbia - An Application of the Hands on Method. in Biotechnology and Biotechnological Equipment, 24(2), 306-310.
https://doi.org/10.1080/13102818.2010.10817852

Miličić D, Karan-Znidarsic T, Pavković-Lučić S, Lucic L, Jokić S. Teaching in Biological Sciences At Primary Schools in Serbia - An Application of the Hands on Method. in Biotechnology and Biotechnological Equipment. 2010;24(2):306-310.
doi:10.1080/13102818.2010.10817852 .

Miličić, Dragana, Karan-Znidarsic, Tamara, Pavković-Lučić, Sofija, Lucic, Luka, Jokić, Stevan, "Teaching in Biological Sciences At Primary Schools in Serbia - An Application of the Hands on Method" in Biotechnology and Biotechnological Equipment, 24, no. 2 (2010):306-310,
https://doi.org/10.1080/13102818.2010.10817852 . .