TY  - JOUR
AU  - Buha-Marković, Jovana
AU  - Marinković, Ana
AU  - Savić, Jasmina
AU  - Krstić, Aleksandar
AU  - Savić, Andrija
AU  - Ristic, Mirjana
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12283
AB  - Lignite and coal waste used as feed fuels in thermal power plants (TPPs) and semi-industrial fluidized bed boiler (FBB), as well as their representative fly ashes (FAs), were examined. Fly ashes were compared employing anions and cations content in correspondent water extracts, trace elements and polycyclic aromatic hydrocarbon concentrations, as well as health risk assessments of substances known to be of concern for public health. Fluoride and sulfate contents in water extracted FAs are far below the legislation limits for waste, classifying all investigated FAs as non-hazardous. Among investigated trace elements, Cd content is the lowest, while Mn content is the highest. The highest enrichment ratios are noticed for As, Pb, Hg, Cu, V and Cr. The results indicate that total PAHs content is elevated in FA from the combustion of coal waste (AFB), with fluoranthene prevailing. The cancer risk of As and the non-cancer risk of As and Ni in some FAs surpass their respective permissible limits. The incremental lifetime cancer risk of an adult population indicates a potential PAHs risk in AFB, whereas all other fly ashes are within safe limits.
AB  - У овом раду, испитивана су горива (лигнит и отпадни угаљ) која се користе у термоелектранама и полуиндустријском постројењу са флуидизованим слојем, као и летећи пепели добијени њиховим сагоревањем. Летећи пепели су упоређени на основу: садржаја анјона и катјона у њиховим воденим екстрактима, концентрације елемената у траговима и полицикличних ароматичних угљоводоника (PAH), као и процене здравственог ризика који потиче од претходно поменутих потенцијално опасних супстанци. Садржај флуорида и сулфата у воденим екстрактима летећих пепела далеко је испод законски дозвољених граница за отпад, на основу чега се могу сврстати у безопасне. Од испитиваних елемената у траговима, садржај Cd је најнижи, док је концентрација Mn највиша. Највеће обогаћење пепела у односу на одговарајући угаљ, примећено је за As, Pb, Hg, Cu, V и Cr. На основу добијених резултата показано је да је укупни садржај PAH највећи за летећи пепео добијен сагоревањем отпадног угља. Међу испитиваним PAH, највишу концентрацију има флуорантен. Ризици који потичу од арсена (међу канцерогеним елементима), као и арсена и никла (међу неканцерогеним елементима), премашују дозвољене граничне вредности. Вредност процењеног ризика од рака код одрасле популације у случају PAH, показује да за летећи пепео добијен сагоревањем отпадног угља постоји потенцијални ризик, док су вредности за остале пепеле унутар дозвољених граница.
T2  - Journal of the Serbian Chemical Society
T1  - Health risk assessment of potentially harmful substances from fly ashes generated by coal and coal waste combustion
T1  - Процена ризика за потенцијално опасне супстанце из летећих пепела добијених сагоревањем угља и отпадног угља
VL  - 88
IS  - 11
SP  - 1161
EP  - 1173
DO  - 10.2298/JSC220130048M
ER  - 

@article{
author = "Buha-Marković, Jovana and Marinković, Ana and Savić, Jasmina and Krstić, Aleksandar and Savić, Andrija and Ristic, Mirjana",
year = "2023",
abstract = "Lignite and coal waste used as feed fuels in thermal power plants (TPPs) and semi-industrial fluidized bed boiler (FBB), as well as their representative fly ashes (FAs), were examined. Fly ashes were compared employing anions and cations content in correspondent water extracts, trace elements and polycyclic aromatic hydrocarbon concentrations, as well as health risk assessments of substances known to be of concern for public health. Fluoride and sulfate contents in water extracted FAs are far below the legislation limits for waste, classifying all investigated FAs as non-hazardous. Among investigated trace elements, Cd content is the lowest, while Mn content is the highest. The highest enrichment ratios are noticed for As, Pb, Hg, Cu, V and Cr. The results indicate that total PAHs content is elevated in FA from the combustion of coal waste (AFB), with fluoranthene prevailing. The cancer risk of As and the non-cancer risk of As and Ni in some FAs surpass their respective permissible limits. The incremental lifetime cancer risk of an adult population indicates a potential PAHs risk in AFB, whereas all other fly ashes are within safe limits., У овом раду, испитивана су горива (лигнит и отпадни угаљ) која се користе у термоелектранама и полуиндустријском постројењу са флуидизованим слојем, као и летећи пепели добијени њиховим сагоревањем. Летећи пепели су упоређени на основу: садржаја анјона и катјона у њиховим воденим екстрактима, концентрације елемената у траговима и полицикличних ароматичних угљоводоника (PAH), као и процене здравственог ризика који потиче од претходно поменутих потенцијално опасних супстанци. Садржај флуорида и сулфата у воденим екстрактима летећих пепела далеко је испод законски дозвољених граница за отпад, на основу чега се могу сврстати у безопасне. Од испитиваних елемената у траговима, садржај Cd је најнижи, док је концентрација Mn највиша. Највеће обогаћење пепела у односу на одговарајући угаљ, примећено је за As, Pb, Hg, Cu, V и Cr. На основу добијених резултата показано је да је укупни садржај PAH највећи за летећи пепео добијен сагоревањем отпадног угља. Међу испитиваним PAH, највишу концентрацију има флуорантен. Ризици који потичу од арсена (међу канцерогеним елементима), као и арсена и никла (међу неканцерогеним елементима), премашују дозвољене граничне вредности. Вредност процењеног ризика од рака код одрасле популације у случају PAH, показује да за летећи пепео добијен сагоревањем отпадног угља постоји потенцијални ризик, док су вредности за остале пепеле унутар дозвољених граница.",
journal = "Journal of the Serbian Chemical Society",
title = "Health risk assessment of potentially harmful substances from fly ashes generated by coal and coal waste combustion, Процена ризика за потенцијално опасне супстанце из летећих пепела добијених сагоревањем угља и отпадног угља",
volume = "88",
number = "11",
pages = "1161-1173",
doi = "10.2298/JSC220130048M"
}

Buha-Marković, J., Marinković, A., Savić, J., Krstić, A., Savić, A.,& Ristic, M.. (2023). Health risk assessment of potentially harmful substances from fly ashes generated by coal and coal waste combustion. in Journal of the Serbian Chemical Society, 88(11), 1161-1173.
https://doi.org/10.2298/JSC220130048M

Buha-Marković J, Marinković A, Savić J, Krstić A, Savić A, Ristic M. Health risk assessment of potentially harmful substances from fly ashes generated by coal and coal waste combustion. in Journal of the Serbian Chemical Society. 2023;88(11):1161-1173.
doi:10.2298/JSC220130048M .

Buha-Marković, Jovana, Marinković, Ana, Savić, Jasmina, Krstić, Aleksandar, Savić, Andrija, Ristic, Mirjana, "Health risk assessment of potentially harmful substances from fly ashes generated by coal and coal waste combustion" in Journal of the Serbian Chemical Society, 88, no. 11 (2023):1161-1173,
https://doi.org/10.2298/JSC220130048M . .

TY  - JOUR
AU  - Buha-Marković, Jovana Z.
AU  - Marinković, Ana D.
AU  - Savić, Jasmina
AU  - Mladenović, Milica R.
AU  - Erić, Milić D.
AU  - Marković, Zoran J.
AU  - Ristić, Mirjana Đ.
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10932
AB  - Emission factors (EFs) of gaseous pollutants, particulate matter, certain harmful trace elements, and polycyclic aromatic hydrocarbons (PAHs) from three thermal power plants (TPPs) and semi-industrial fluidized bed boiler (FBB) were compared. EFs of particulate matter, trace elements (except Cd and Pb), benzo[a]pyrene, and benzo[b]fluoranthene exceed the upper limits specified in the EMEP inventory guidebook for all combustion facilities. The comparison of trace elements and PAHs content in fly ashes (FAs) from lignite and coal waste combustion in TPPs and FBB, respectively, as well as the potential environmental impact of FAs disposal, was performed by employing a set of ecological indicators such as crustal enrichment factor, risk assessment code, risk indices for trace elements, and benzo[a]pyrene equivalent concentration for PAHs. Sequential analysis shows that the trace elements portion is the lowest for water-soluble and exchangeable fractions. The highest enrichment levels in FAs are noticed for As and Hg. Based on toxic trace elements content, FAs from TPPs represent a very high ecological risk, whereas fly ash from FBB poses a moderate ecological risk but has the highest benzo[a]pyrene equivalent concentration, indicating its increased carcinogenic potential. Lead isotope ratios for Serbian coals and FAs can contribute to a lead pollution global database.
T2  - Toxics
T1  - Risk Evaluation of Pollutants Emission from Coal and Coal Waste Combustion Plants and Environmental Impact of Fly Ash Landfilling
VL  - 11
IS  - 4
SP  - 396
DO  - 10.3390/toxics11040396
ER  - 

@article{
author = "Buha-Marković, Jovana Z. and Marinković, Ana D. and Savić, Jasmina and Mladenović, Milica R. and Erić, Milić D. and Marković, Zoran J. and Ristić, Mirjana Đ.",
year = "2023",
abstract = "Emission factors (EFs) of gaseous pollutants, particulate matter, certain harmful trace elements, and polycyclic aromatic hydrocarbons (PAHs) from three thermal power plants (TPPs) and semi-industrial fluidized bed boiler (FBB) were compared. EFs of particulate matter, trace elements (except Cd and Pb), benzo[a]pyrene, and benzo[b]fluoranthene exceed the upper limits specified in the EMEP inventory guidebook for all combustion facilities. The comparison of trace elements and PAHs content in fly ashes (FAs) from lignite and coal waste combustion in TPPs and FBB, respectively, as well as the potential environmental impact of FAs disposal, was performed by employing a set of ecological indicators such as crustal enrichment factor, risk assessment code, risk indices for trace elements, and benzo[a]pyrene equivalent concentration for PAHs. Sequential analysis shows that the trace elements portion is the lowest for water-soluble and exchangeable fractions. The highest enrichment levels in FAs are noticed for As and Hg. Based on toxic trace elements content, FAs from TPPs represent a very high ecological risk, whereas fly ash from FBB poses a moderate ecological risk but has the highest benzo[a]pyrene equivalent concentration, indicating its increased carcinogenic potential. Lead isotope ratios for Serbian coals and FAs can contribute to a lead pollution global database.",
journal = "Toxics",
title = "Risk Evaluation of Pollutants Emission from Coal and Coal Waste Combustion Plants and Environmental Impact of Fly Ash Landfilling",
volume = "11",
number = "4",
pages = "396",
doi = "10.3390/toxics11040396"
}

Buha-Marković, J. Z., Marinković, A. D., Savić, J., Mladenović, M. R., Erić, M. D., Marković, Z. J.,& Ristić, M. Đ.. (2023). Risk Evaluation of Pollutants Emission from Coal and Coal Waste Combustion Plants and Environmental Impact of Fly Ash Landfilling. in Toxics, 11(4), 396.
https://doi.org/10.3390/toxics11040396

Buha-Marković JZ, Marinković AD, Savić J, Mladenović MR, Erić MD, Marković ZJ, Ristić MĐ. Risk Evaluation of Pollutants Emission from Coal and Coal Waste Combustion Plants and Environmental Impact of Fly Ash Landfilling. in Toxics. 2023;11(4):396.
doi:10.3390/toxics11040396 .

Buha-Marković, Jovana Z., Marinković, Ana D., Savić, Jasmina, Mladenović, Milica R., Erić, Milić D., Marković, Zoran J., Ristić, Mirjana Đ., "Risk Evaluation of Pollutants Emission from Coal and Coal Waste Combustion Plants and Environmental Impact of Fly Ash Landfilling" in Toxics, 11, no. 4 (2023):396,
https://doi.org/10.3390/toxics11040396 . .

TY  - JOUR
AU  - Marinković, Ana
AU  - Savić, Jasmina
AU  - Mladenović, Milica
AU  - Buha-Marković, Jovana
AU  - Petrov, Nevena
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/11993
AB  - Despite many benefits of agricultural biomass utilization as an energy source, there are certain disadvantages such as the possible high emission of NOx. The NOx emission represents one of the key challenges for agricultural biomass use as a fuel. The experimental denitrification chamber was used to evaluate the impact of initial NO content, NH3:NO molar ratio, flue gas temperature, and the temperature difference between two denitrification chamber sections on NOx reduction using ammonia aqueous solution. The optimization of experimental conditions was done in the NO concentration range from 200-800 ppm, NH3:NO molar ratios from 0.31-3 and second chamber section temperature range from 770-67°C. The denitrification process under controlled conditions is the starting point for the optimization of the secondary denitrification technique of selective non-catalytic reduction SNCR process on real-scale plants combusting biomass or any other fuels with increased NOx emission.
T2  - Thermal Science
T1  - Selective non-catalytic denitrification of biomass combustion flue gases (synthetic mixture)
VL  - 27
IS  - 5 Part A
SP  - 3635
EP  - 3647
DO  - 10.2298/TSCI221202056M
ER  - 

@article{
author = "Marinković, Ana and Savić, Jasmina and Mladenović, Milica and Buha-Marković, Jovana and Petrov, Nevena",
year = "2023",
abstract = "Despite many benefits of agricultural biomass utilization as an energy source, there are certain disadvantages such as the possible high emission of NOx. The NOx emission represents one of the key challenges for agricultural biomass use as a fuel. The experimental denitrification chamber was used to evaluate the impact of initial NO content, NH3:NO molar ratio, flue gas temperature, and the temperature difference between two denitrification chamber sections on NOx reduction using ammonia aqueous solution. The optimization of experimental conditions was done in the NO concentration range from 200-800 ppm, NH3:NO molar ratios from 0.31-3 and second chamber section temperature range from 770-67°C. The denitrification process under controlled conditions is the starting point for the optimization of the secondary denitrification technique of selective non-catalytic reduction SNCR process on real-scale plants combusting biomass or any other fuels with increased NOx emission.",
journal = "Thermal Science",
title = "Selective non-catalytic denitrification of biomass combustion flue gases (synthetic mixture)",
volume = "27",
number = "5 Part A",
pages = "3635-3647",
doi = "10.2298/TSCI221202056M"
}

Marinković, A., Savić, J., Mladenović, M., Buha-Marković, J.,& Petrov, N.. (2023). Selective non-catalytic denitrification of biomass combustion flue gases (synthetic mixture). in Thermal Science, 27(5 Part A), 3635-3647.
https://doi.org/10.2298/TSCI221202056M

Marinković A, Savić J, Mladenović M, Buha-Marković J, Petrov N. Selective non-catalytic denitrification of biomass combustion flue gases (synthetic mixture). in Thermal Science. 2023;27(5 Part A):3635-3647.
doi:10.2298/TSCI221202056M .

Marinković, Ana, Savić, Jasmina, Mladenović, Milica, Buha-Marković, Jovana, Petrov, Nevena, "Selective non-catalytic denitrification of biomass combustion flue gases (synthetic mixture)" in Thermal Science, 27, no. 5 Part A (2023):3635-3647,
https://doi.org/10.2298/TSCI221202056M . .

TY  - JOUR
AU  - Marinković, Ana D.
AU  - Buha-Marković, Jovana Z.
AU  - Savić, Jasmina
AU  - Mladenović, Milica R.
AU  - Petrov, Nevena
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10554
AB  - Agricultural biomass is considered a preferred RES in Serbia because of its availability and suitability to limit the use of fossil fuel resources and reduce GHG emissions. Therefore, constant work has been done to develop technologies that enable its utilization for energy purposes. As an example of these efforts, in the Agricultural Corporation PKB, the soybean straw cigarette-type combustion system has been applied for greenhouse heating for over a decade. However, many volatile and semivolatile organic compounds are emitted directly into the atmosphere or concentrated in ash particles during agricultural biomass combustion. Since some of the emitted compounds, such as polycyclic aromatic hydrocarbons (PAHs), are toxic, monitoring their concentrations in fly ash is recommended. Literature data regarding PAHs content in agricultural biomass ashes are insubstantial, especially in Serbia. For that purpose, PAHs contents in the cyclone and stack fly ashes of soybean straw were investigated and compared. In addition, the emission factors, toxicity, carcinogenicity and benzo[a]pyrene equivalence concentrations were determined and used to estimate the potential environmental impact of these ashes. As a result, stack ash has been shown to have a higher potential environmental risk than cyclone ash. Hence, an assessment of using soybean straw as a feed fuel in a real cigarette-type combustion plant regarding PAHs emission is given. These results provide important information for optimizing combustion conditions and assisting the local entities in managing air pollution and control policies in Serbia.
T2  - Thermal Science
T1  - Polycyclic aromatic hydrocarbons emission from cigar burner combustion system and comparison of their content in fly ashes
VL  - 26
IS  - 6 Part A
SP  - 4749
EP  - 4761
DO  - 10.2298/TSCI220616138M
ER  - 

@article{
author = "Marinković, Ana D. and Buha-Marković, Jovana Z. and Savić, Jasmina and Mladenović, Milica R. and Petrov, Nevena",
year = "2022",
abstract = "Agricultural biomass is considered a preferred RES in Serbia because of its availability and suitability to limit the use of fossil fuel resources and reduce GHG emissions. Therefore, constant work has been done to develop technologies that enable its utilization for energy purposes. As an example of these efforts, in the Agricultural Corporation PKB, the soybean straw cigarette-type combustion system has been applied for greenhouse heating for over a decade. However, many volatile and semivolatile organic compounds are emitted directly into the atmosphere or concentrated in ash particles during agricultural biomass combustion. Since some of the emitted compounds, such as polycyclic aromatic hydrocarbons (PAHs), are toxic, monitoring their concentrations in fly ash is recommended. Literature data regarding PAHs content in agricultural biomass ashes are insubstantial, especially in Serbia. For that purpose, PAHs contents in the cyclone and stack fly ashes of soybean straw were investigated and compared. In addition, the emission factors, toxicity, carcinogenicity and benzo[a]pyrene equivalence concentrations were determined and used to estimate the potential environmental impact of these ashes. As a result, stack ash has been shown to have a higher potential environmental risk than cyclone ash. Hence, an assessment of using soybean straw as a feed fuel in a real cigarette-type combustion plant regarding PAHs emission is given. These results provide important information for optimizing combustion conditions and assisting the local entities in managing air pollution and control policies in Serbia.",
journal = "Thermal Science",
title = "Polycyclic aromatic hydrocarbons emission from cigar burner combustion system and comparison of their content in fly ashes",
volume = "26",
number = "6 Part A",
pages = "4749-4761",
doi = "10.2298/TSCI220616138M"
}

Marinković, A. D., Buha-Marković, J. Z., Savić, J., Mladenović, M. R.,& Petrov, N.. (2022). Polycyclic aromatic hydrocarbons emission from cigar burner combustion system and comparison of their content in fly ashes. in Thermal Science, 26(6 Part A), 4749-4761.
https://doi.org/10.2298/TSCI220616138M

Marinković AD, Buha-Marković JZ, Savić J, Mladenović MR, Petrov N. Polycyclic aromatic hydrocarbons emission from cigar burner combustion system and comparison of their content in fly ashes. in Thermal Science. 2022;26(6 Part A):4749-4761.
doi:10.2298/TSCI220616138M .

Marinković, Ana D., Buha-Marković, Jovana Z., Savić, Jasmina, Mladenović, Milica R., Petrov, Nevena, "Polycyclic aromatic hydrocarbons emission from cigar burner combustion system and comparison of their content in fly ashes" in Thermal Science, 26, no. 6 Part A (2022):4749-4761,
https://doi.org/10.2298/TSCI220616138M . .

TY  - JOUR
AU  - Valenta-Šobot, Ana
AU  - Savić, Jasmina
AU  - Filipović Tričković, Jelena G.
AU  - Drakulić, Dunja R.
AU  - Joksić, Gordana
PY  - 2020
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10254
AB  - Root of Gentiana lutea commercially available as gentian root, a natural antidote for different types of poisons, possess antioxidative, immunomodulatory, cytoprotective and anti-inflammatory, and adverse, genotoxic and mutagenic effects. It has monoterpenes loganic acid, swertiamarin, gentiopicroside and sweroside as most abundant constituents. In this study, we assessed the toxicity of monoterpenes’ reactive molecular fragments using in silico prediction by VEGA-QSAR platform. Further, we compared the data obtained with in vitro geno- and cyto- toxicity testing of the above monoterpenes and the G. lutea root extract (GE), on human primary unstimulated and mitogen-stimulated peripheral blood mononuclear cells (PBMCs). Viability was assessed by TB and XTT tests after 48 h treatment. DNA damage was evaluated by alkaline comet assay on unstimulated cells, whereas cytokinesis-block micronucleus assay was employed on mitogen-stimulated PBMCs. Stability of compounds throughout treatment was monitored by UPLC. The observed in vitro results had highest compliance with in silico IRFMN/ISSCAN-CGX prediction model. Compounds showed high stability during experiment while treatment with single compounds reduced number of viable cells and increased DNA damage. GE treatment had toxic impact on unstimulated PBMCs but no significant genotoxic influence on mitogen-stimulated PBMCs. In summary, the mild GE effect suggests that the complexity of crude GE extract chemical composition  may attenuate the toxicity of the tested monoterpenes loganic acid, swertiamarin, gentiopicroside and sweroside.
T2  - Indian Journal of Experimental Biology
T1  - Toxicity assessment of Gentiana lutea L. root extract and its monoterpene compounds
VL  - 58
IS  - 9
SP  - 609
EP  - 616
DO  - 10.56042/ijeb.v58i09.39874
UR  - https://hdl.handle.net/21.15107/rcub_vinar_10254
ER  - 

@article{
author = "Valenta-Šobot, Ana and Savić, Jasmina and Filipović Tričković, Jelena G. and Drakulić, Dunja R. and Joksić, Gordana",
year = "2020",
abstract = "Root of Gentiana lutea commercially available as gentian root, a natural antidote for different types of poisons, possess antioxidative, immunomodulatory, cytoprotective and anti-inflammatory, and adverse, genotoxic and mutagenic effects. It has monoterpenes loganic acid, swertiamarin, gentiopicroside and sweroside as most abundant constituents. In this study, we assessed the toxicity of monoterpenes’ reactive molecular fragments using in silico prediction by VEGA-QSAR platform. Further, we compared the data obtained with in vitro geno- and cyto- toxicity testing of the above monoterpenes and the G. lutea root extract (GE), on human primary unstimulated and mitogen-stimulated peripheral blood mononuclear cells (PBMCs). Viability was assessed by TB and XTT tests after 48 h treatment. DNA damage was evaluated by alkaline comet assay on unstimulated cells, whereas cytokinesis-block micronucleus assay was employed on mitogen-stimulated PBMCs. Stability of compounds throughout treatment was monitored by UPLC. The observed in vitro results had highest compliance with in silico IRFMN/ISSCAN-CGX prediction model. Compounds showed high stability during experiment while treatment with single compounds reduced number of viable cells and increased DNA damage. GE treatment had toxic impact on unstimulated PBMCs but no significant genotoxic influence on mitogen-stimulated PBMCs. In summary, the mild GE effect suggests that the complexity of crude GE extract chemical composition  may attenuate the toxicity of the tested monoterpenes loganic acid, swertiamarin, gentiopicroside and sweroside.",
journal = "Indian Journal of Experimental Biology",
title = "Toxicity assessment of Gentiana lutea L. root extract and its monoterpene compounds",
volume = "58",
number = "9",
pages = "609-616",
doi = "10.56042/ijeb.v58i09.39874",
url = "https://hdl.handle.net/21.15107/rcub_vinar_10254"
}

Valenta-Šobot, A., Savić, J., Filipović Tričković, J. G., Drakulić, D. R.,& Joksić, G.. (2020). Toxicity assessment of Gentiana lutea L. root extract and its monoterpene compounds. in Indian Journal of Experimental Biology, 58(9), 609-616.
https://doi.org/10.56042/ijeb.v58i09.39874
https://hdl.handle.net/21.15107/rcub_vinar_10254

Valenta-Šobot A, Savić J, Filipović Tričković JG, Drakulić DR, Joksić G. Toxicity assessment of Gentiana lutea L. root extract and its monoterpene compounds. in Indian Journal of Experimental Biology. 2020;58(9):609-616.
doi:10.56042/ijeb.v58i09.39874
https://hdl.handle.net/21.15107/rcub_vinar_10254 .

Valenta-Šobot, Ana, Savić, Jasmina, Filipović Tričković, Jelena G., Drakulić, Dunja R., Joksić, Gordana, "Toxicity assessment of Gentiana lutea L. root extract and its monoterpene compounds" in Indian Journal of Experimental Biology, 58, no. 9 (2020):609-616,
https://doi.org/10.56042/ijeb.v58i09.39874 .,
https://hdl.handle.net/21.15107/rcub_vinar_10254 .

TY  - JOUR
AU  - Jovanović, Maja
AU  - Savić, Jasmina
AU  - Kovačević, Renata
AU  - Tasić, Viša
AU  - Todorović, Žaklina
AU  - Stevanović, Svetlana
AU  - Manojlović, Dragan D.
AU  - Jovašević-Stojanović, Milena
PY  - 2020
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3820
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8750
AB  - Urban airborne particles contain a wide spectrum of components, known to have harmful effects on human health. This study reports a detailed investigation of fine particulate matter (PM2.5), chemical content and oxidative potential derived from two different urban environments. During summer and winter, 20-day campaigns were conducted at Belgrade city center (urban-background site – UB) and Bor (urban-industrial site – UI). Using various analytical techniques, carbonaceous compounds, water-soluble inorganic ions, major and trace elements were determined, while the oxidative potential of PM2.5 was estimated by dichloro-dihydro-fluorescein diacetate (DCFH-DA) assay (OPDCFH values). The mean PM2.5 concentrations in both urban environments were above the recommended daily value, and the dominant PM2.5 mass contributor was organic matter (29–55%). The OC/EC ratio was significantly higher at UB site during winter, which was an indication of a considerable contribution of secondary organic carbon to the overall organic carbon (OC). Water-soluble organic carbon (WSOC) was also higher at UB than at UI site, and it probably came from the same sources as OC. In general, the different partition of secondary organic aerosol (SOA) in warm and cold periods affected the number of organic components. Sulfates and nitrates were the most abundant ions at both sites and they counted approximately 40% (summer) and 50% (winter) of total ions. Further, the concentrations of the most elements, particularly some potentially carcinogenic elements such as As, Cd and Pb were significantly higher at UI, due to the emissions from the copper smelter complex in the vicinity. The mean OPDCFH values were similar during the summer at both sampling sites, whereas a statistically significant difference between sites was noticed in favor of UB environment in winter.
T2  - Science of the Total Environment
T1  - Comparison of fine particulate matter level, chemical content and oxidative potential derived from two dissimilar urban environments
VL  - 708
SP  - 135209
DO  - 10.1016/j.scitotenv.2019.135209
ER  - 

@article{
author = "Jovanović, Maja and Savić, Jasmina and Kovačević, Renata and Tasić, Viša and Todorović, Žaklina and Stevanović, Svetlana and Manojlović, Dragan D. and Jovašević-Stojanović, Milena",
year = "2020",
abstract = "Urban airborne particles contain a wide spectrum of components, known to have harmful effects on human health. This study reports a detailed investigation of fine particulate matter (PM2.5), chemical content and oxidative potential derived from two different urban environments. During summer and winter, 20-day campaigns were conducted at Belgrade city center (urban-background site – UB) and Bor (urban-industrial site – UI). Using various analytical techniques, carbonaceous compounds, water-soluble inorganic ions, major and trace elements were determined, while the oxidative potential of PM2.5 was estimated by dichloro-dihydro-fluorescein diacetate (DCFH-DA) assay (OPDCFH values). The mean PM2.5 concentrations in both urban environments were above the recommended daily value, and the dominant PM2.5 mass contributor was organic matter (29–55%). The OC/EC ratio was significantly higher at UB site during winter, which was an indication of a considerable contribution of secondary organic carbon to the overall organic carbon (OC). Water-soluble organic carbon (WSOC) was also higher at UB than at UI site, and it probably came from the same sources as OC. In general, the different partition of secondary organic aerosol (SOA) in warm and cold periods affected the number of organic components. Sulfates and nitrates were the most abundant ions at both sites and they counted approximately 40% (summer) and 50% (winter) of total ions. Further, the concentrations of the most elements, particularly some potentially carcinogenic elements such as As, Cd and Pb were significantly higher at UI, due to the emissions from the copper smelter complex in the vicinity. The mean OPDCFH values were similar during the summer at both sampling sites, whereas a statistically significant difference between sites was noticed in favor of UB environment in winter.",
journal = "Science of the Total Environment",
title = "Comparison of fine particulate matter level, chemical content and oxidative potential derived from two dissimilar urban environments",
volume = "708",
pages = "135209",
doi = "10.1016/j.scitotenv.2019.135209"
}

Jovanović, M., Savić, J., Kovačević, R., Tasić, V., Todorović, Ž., Stevanović, S., Manojlović, D. D.,& Jovašević-Stojanović, M.. (2020). Comparison of fine particulate matter level, chemical content and oxidative potential derived from two dissimilar urban environments. in Science of the Total Environment, 708, 135209.
https://doi.org/10.1016/j.scitotenv.2019.135209

Jovanović M, Savić J, Kovačević R, Tasić V, Todorović Ž, Stevanović S, Manojlović DD, Jovašević-Stojanović M. Comparison of fine particulate matter level, chemical content and oxidative potential derived from two dissimilar urban environments. in Science of the Total Environment. 2020;708:135209.
doi:10.1016/j.scitotenv.2019.135209 .

Jovanović, Maja, Savić, Jasmina, Kovačević, Renata, Tasić, Viša, Todorović, Žaklina, Stevanović, Svetlana, Manojlović, Dragan D., Jovašević-Stojanović, Milena, "Comparison of fine particulate matter level, chemical content and oxidative potential derived from two dissimilar urban environments" in Science of the Total Environment, 708 (2020):135209,
https://doi.org/10.1016/j.scitotenv.2019.135209 . .

TY  - JOUR
AU  - Buha Marković, Jovana
AU  - Marinković, Ana D.
AU  - Nemoda, Stevan
AU  - Savić, Jasmina
PY  - 2020
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9124
AB  - The comparison of fly ash generated from lignite combustion in a thermal power plant Kolubara A (Veliki Crljeni) and bottom and fly ash from coal waste combustion in a semi-industrial fluidized bed boiler (Vinča) was performed as the function of particle size. The average total concentrations of the 16 EPA priority PAHs in ash fractions are 0.49 mg kg−1 of ash (thermal power plant) and 17.48 mg kg−1 of ash (fluidized bed boiler). The sum of 3- and 4-ring PAHs accounts for more than 93% of overall PAHs concentration, and the most abundant among them is fluoranthene. The portions of PAHs groups defined based on their physico-chemical properties, as obtained from quantitative structure-activity relationship (QSAR) models included in the Vega platform, were determined. These portions, emission factors, and benzo[a]pyrene equivalence concentrations were further on used to estimate the potential environmental impact of ash disposal. The PAHs emission factors are higher compared to values in the air pollutant emission inventory guidebook of the cooperative program for monitoring and evaluation of the long-range transmission of air pollutants in Europe (EMEP/EEA). The overall emission factors of 16 PAHs for combustion of lignite and coal waste are determined to be 0.15 and 249.97 mg kg−1 of fuel, respectively. Based on the ratios of benzo[a]pyrene equivalence concentrations of each ash and correspondent fuel, the disposal of fly ash from the cyclone of fluidized bed boiler represents the highest risk to the environment among tested ashes.
T2  - Environmental Pollution
T1  - Distribution of PAHs in coal ashes from the thermal power plant and fluidized bed combustion system; estimation of environmental risk of ash disposal
VL  - 266
SP  - 115282
DO  - 10.1016/j.envpol.2020.115282
ER  - 

@article{
author = "Buha Marković, Jovana and Marinković, Ana D. and Nemoda, Stevan and Savić, Jasmina",
year = "2020",
abstract = "The comparison of fly ash generated from lignite combustion in a thermal power plant Kolubara A (Veliki Crljeni) and bottom and fly ash from coal waste combustion in a semi-industrial fluidized bed boiler (Vinča) was performed as the function of particle size. The average total concentrations of the 16 EPA priority PAHs in ash fractions are 0.49 mg kg−1 of ash (thermal power plant) and 17.48 mg kg−1 of ash (fluidized bed boiler). The sum of 3- and 4-ring PAHs accounts for more than 93% of overall PAHs concentration, and the most abundant among them is fluoranthene. The portions of PAHs groups defined based on their physico-chemical properties, as obtained from quantitative structure-activity relationship (QSAR) models included in the Vega platform, were determined. These portions, emission factors, and benzo[a]pyrene equivalence concentrations were further on used to estimate the potential environmental impact of ash disposal. The PAHs emission factors are higher compared to values in the air pollutant emission inventory guidebook of the cooperative program for monitoring and evaluation of the long-range transmission of air pollutants in Europe (EMEP/EEA). The overall emission factors of 16 PAHs for combustion of lignite and coal waste are determined to be 0.15 and 249.97 mg kg−1 of fuel, respectively. Based on the ratios of benzo[a]pyrene equivalence concentrations of each ash and correspondent fuel, the disposal of fly ash from the cyclone of fluidized bed boiler represents the highest risk to the environment among tested ashes.",
journal = "Environmental Pollution",
title = "Distribution of PAHs in coal ashes from the thermal power plant and fluidized bed combustion system; estimation of environmental risk of ash disposal",
volume = "266",
pages = "115282",
doi = "10.1016/j.envpol.2020.115282"
}

Buha Marković, J., Marinković, A. D., Nemoda, S.,& Savić, J.. (2020). Distribution of PAHs in coal ashes from the thermal power plant and fluidized bed combustion system; estimation of environmental risk of ash disposal. in Environmental Pollution, 266, 115282.
https://doi.org/10.1016/j.envpol.2020.115282

Buha Marković J, Marinković AD, Nemoda S, Savić J. Distribution of PAHs in coal ashes from the thermal power plant and fluidized bed combustion system; estimation of environmental risk of ash disposal. in Environmental Pollution. 2020;266:115282.
doi:10.1016/j.envpol.2020.115282 .

Buha Marković, Jovana, Marinković, Ana D., Nemoda, Stevan, Savić, Jasmina, "Distribution of PAHs in coal ashes from the thermal power plant and fluidized bed combustion system; estimation of environmental risk of ash disposal" in Environmental Pollution, 266 (2020):115282,
https://doi.org/10.1016/j.envpol.2020.115282 . .

TY  - JOUR
AU  - Valenta-Šobot, Ana
AU  - Drakulić, Dunja R.
AU  - Joksić, Gordana
AU  - Miletić Vukajlović, Jadranka
AU  - Savić, Jasmina
AU  - Potočnik, Jelena
AU  - Filipović Tričković, Jelena G.
PY  - 2020
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9523
AB  - Yellow gentian (Gentiana lutea L.), a medicinal plant widely used in traditional medicine, displays multiple biological effects, ranging from beneficial to toxic. Since many promising applications have been reported so far, our aim was to evaluate its potential concentration- and time- dependent cytotoxic and genotoxic effects in vitro . To that end we exposed human peripheral blood mononuclear cells to 0.5, 1, and 2 mg/mL of yellow gentian root extract (YGRE) to determine its effects on oxidative stress parameters [pro/antioxidant balance (PAB) and lipid peroxidation], DNA damage (alkaline comet assay and chromosome aberrations), and cell viability (trypan blue exclusion test). Cell viability decreased with increasing concentrations and treatment duration. Only the lowest YGRE concentration (0.5 mg/mL) increased oxidative stress but produced minor DNA damage and cytotoxicity. At higher concentrations, redox parameters returned to near control values. The percentage of chromosome aberrations and percentage of DNA in the comet tail increased with increased YGRE concentration after 48 h and declined after 72 h of treatment. This points to the activation of DNA repair mechanism (homologous recombination), evidenced by the formation of chromosomal radial figures after 72 h of treatment with the highest YGRE concentration of 2 mg/mL. Our results suggest that YGRE, despite induction of cytotoxic and genotoxic effects, activates cell repair mechanisms that counter oxidative and DNA lesions and induce cell death in highly damaged cells. Therefore, observed protective effects of yellow gentian after longer exposure could be a result of activated repair and removal of cells with irreparable damage.
T2  - Archives of Industrial Hygiene and Toxicology
T1  - Yellow gentian root extract provokes concentration- and time-dependent response in peripheral blood mononuclear cells
VL  - 71
IS  - 4
SP  - 320
EP  - 328
DO  - 10.2478/aiht-2020-71-3476
ER  - 

@article{
author = "Valenta-Šobot, Ana and Drakulić, Dunja R. and Joksić, Gordana and Miletić Vukajlović, Jadranka and Savić, Jasmina and Potočnik, Jelena and Filipović Tričković, Jelena G.",
year = "2020",
abstract = "Yellow gentian (Gentiana lutea L.), a medicinal plant widely used in traditional medicine, displays multiple biological effects, ranging from beneficial to toxic. Since many promising applications have been reported so far, our aim was to evaluate its potential concentration- and time- dependent cytotoxic and genotoxic effects in vitro . To that end we exposed human peripheral blood mononuclear cells to 0.5, 1, and 2 mg/mL of yellow gentian root extract (YGRE) to determine its effects on oxidative stress parameters [pro/antioxidant balance (PAB) and lipid peroxidation], DNA damage (alkaline comet assay and chromosome aberrations), and cell viability (trypan blue exclusion test). Cell viability decreased with increasing concentrations and treatment duration. Only the lowest YGRE concentration (0.5 mg/mL) increased oxidative stress but produced minor DNA damage and cytotoxicity. At higher concentrations, redox parameters returned to near control values. The percentage of chromosome aberrations and percentage of DNA in the comet tail increased with increased YGRE concentration after 48 h and declined after 72 h of treatment. This points to the activation of DNA repair mechanism (homologous recombination), evidenced by the formation of chromosomal radial figures after 72 h of treatment with the highest YGRE concentration of 2 mg/mL. Our results suggest that YGRE, despite induction of cytotoxic and genotoxic effects, activates cell repair mechanisms that counter oxidative and DNA lesions and induce cell death in highly damaged cells. Therefore, observed protective effects of yellow gentian after longer exposure could be a result of activated repair and removal of cells with irreparable damage.",
journal = "Archives of Industrial Hygiene and Toxicology",
title = "Yellow gentian root extract provokes concentration- and time-dependent response in peripheral blood mononuclear cells",
volume = "71",
number = "4",
pages = "320-328",
doi = "10.2478/aiht-2020-71-3476"
}

Valenta-Šobot, A., Drakulić, D. R., Joksić, G., Miletić Vukajlović, J., Savić, J., Potočnik, J.,& Filipović Tričković, J. G.. (2020). Yellow gentian root extract provokes concentration- and time-dependent response in peripheral blood mononuclear cells. in Archives of Industrial Hygiene and Toxicology, 71(4), 320-328.
https://doi.org/10.2478/aiht-2020-71-3476

Valenta-Šobot A, Drakulić DR, Joksić G, Miletić Vukajlović J, Savić J, Potočnik J, Filipović Tričković JG. Yellow gentian root extract provokes concentration- and time-dependent response in peripheral blood mononuclear cells. in Archives of Industrial Hygiene and Toxicology. 2020;71(4):320-328.
doi:10.2478/aiht-2020-71-3476 .

Valenta-Šobot, Ana, Drakulić, Dunja R., Joksić, Gordana, Miletić Vukajlović, Jadranka, Savić, Jasmina, Potočnik, Jelena, Filipović Tričković, Jelena G., "Yellow gentian root extract provokes concentration- and time-dependent response in peripheral blood mononuclear cells" in Archives of Industrial Hygiene and Toxicology, 71, no. 4 (2020):320-328,
https://doi.org/10.2478/aiht-2020-71-3476 . .

TY  - JOUR
AU  - Jovanović, Maja
AU  - Savić, Jasmina
AU  - Salimi, Farhad
AU  - Stevanović, Svetlana
AU  - Brown, Reece A.
AU  - Jovašević-Stojanović, Milena
AU  - Manojlovic, Dragan
AU  - Bartonova, Alena
AU  - Bottle, Steven
AU  - Ristovski, Zoran
PY  - 2019
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8677
AB  - To estimate the oxidative potential (OP) of particulate matter (PM), two commonly used cell-free, molecular probes were applied: dithiothreitol (DTT) and dichloro-dihydro-fluorescein diacetate (DCFH-DA), and their performance was compared with 9,10-bis (phenylethynyl) anthracene-nitroxide (BPEAnit). To the best of our knowledge, this is the first study in which the performance of the DTT and DCFH has been compared with the BPEAnit probe. The average concentrations of PM, organic carbon (OC) and elemental carbon (EC) for fine (PM2.5) and coarse (PM10) particles were determined. The results were 44.8 ± 13.7, 9.8 ± 5.1 and 9.3 ± 4.8 µg·m−3 for PM2.5 and 75.5 ± 25.1, 16.3 ± 8.7 and 11.8 ± 5.3 µg·m−3 for PM10, respectively, for PM, OC and EC. The water-soluble organic carbon (WSOC) fraction accounted for 42 ± 14% and 28 ± 9% of organic carbon in PM2.5 and PM10, respectively. The average volume normalized OP values for the three assays depended on both the sampling periods and the PM fractions. The OPBPEAnit had its peak at 2 p.m.; in the afternoon, it was three times higher compared to the morning and late afternoon values. The DCFH and BPEAnit results were correlated (r = 0.64), while there was no good agreement between the BPEAnit and the DTT (r = 0.14). The total organic content of PM does not necessarily represent oxidative capacity and it shows varying correlation with the OP. With respect to the two PM fractions studied, the OP was mostly associated with smaller particles.
T2  - International Journal of Environmental Research and Public Health
T1  - Measurements of Oxidative Potential of Particulate Matter at Belgrade Tunnel; Comparison of BPEAnit, DTT and DCFH Assays
VL  - 16
IS  - 24
SP  - 4906
DO  - 10.3390/ijerph16244906
ER  - 

@article{
author = "Jovanović, Maja and Savić, Jasmina and Salimi, Farhad and Stevanović, Svetlana and Brown, Reece A. and Jovašević-Stojanović, Milena and Manojlovic, Dragan and Bartonova, Alena and Bottle, Steven and Ristovski, Zoran",
year = "2019",
abstract = "To estimate the oxidative potential (OP) of particulate matter (PM), two commonly used cell-free, molecular probes were applied: dithiothreitol (DTT) and dichloro-dihydro-fluorescein diacetate (DCFH-DA), and their performance was compared with 9,10-bis (phenylethynyl) anthracene-nitroxide (BPEAnit). To the best of our knowledge, this is the first study in which the performance of the DTT and DCFH has been compared with the BPEAnit probe. The average concentrations of PM, organic carbon (OC) and elemental carbon (EC) for fine (PM2.5) and coarse (PM10) particles were determined. The results were 44.8 ± 13.7, 9.8 ± 5.1 and 9.3 ± 4.8 µg·m−3 for PM2.5 and 75.5 ± 25.1, 16.3 ± 8.7 and 11.8 ± 5.3 µg·m−3 for PM10, respectively, for PM, OC and EC. The water-soluble organic carbon (WSOC) fraction accounted for 42 ± 14% and 28 ± 9% of organic carbon in PM2.5 and PM10, respectively. The average volume normalized OP values for the three assays depended on both the sampling periods and the PM fractions. The OPBPEAnit had its peak at 2 p.m.; in the afternoon, it was three times higher compared to the morning and late afternoon values. The DCFH and BPEAnit results were correlated (r = 0.64), while there was no good agreement between the BPEAnit and the DTT (r = 0.14). The total organic content of PM does not necessarily represent oxidative capacity and it shows varying correlation with the OP. With respect to the two PM fractions studied, the OP was mostly associated with smaller particles.",
journal = "International Journal of Environmental Research and Public Health",
title = "Measurements of Oxidative Potential of Particulate Matter at Belgrade Tunnel; Comparison of BPEAnit, DTT and DCFH Assays",
volume = "16",
number = "24",
pages = "4906",
doi = "10.3390/ijerph16244906"
}

Jovanović, M., Savić, J., Salimi, F., Stevanović, S., Brown, R. A., Jovašević-Stojanović, M., Manojlovic, D., Bartonova, A., Bottle, S.,& Ristovski, Z.. (2019). Measurements of Oxidative Potential of Particulate Matter at Belgrade Tunnel; Comparison of BPEAnit, DTT and DCFH Assays. in International Journal of Environmental Research and Public Health, 16(24), 4906.
https://doi.org/10.3390/ijerph16244906

Jovanović M, Savić J, Salimi F, Stevanović S, Brown RA, Jovašević-Stojanović M, Manojlovic D, Bartonova A, Bottle S, Ristovski Z. Measurements of Oxidative Potential of Particulate Matter at Belgrade Tunnel; Comparison of BPEAnit, DTT and DCFH Assays. in International Journal of Environmental Research and Public Health. 2019;16(24):4906.
doi:10.3390/ijerph16244906 .

Jovanović, Maja, Savić, Jasmina, Salimi, Farhad, Stevanović, Svetlana, Brown, Reece A., Jovašević-Stojanović, Milena, Manojlovic, Dragan, Bartonova, Alena, Bottle, Steven, Ristovski, Zoran, "Measurements of Oxidative Potential of Particulate Matter at Belgrade Tunnel; Comparison of BPEAnit, DTT and DCFH Assays" in International Journal of Environmental Research and Public Health, 16, no. 24 (2019):4906,
https://doi.org/10.3390/ijerph16244906 . .

TY  - JOUR
AU  - Savić, Jasmina
AU  - Petrović, Sandra
AU  - Leskovac, Andreja
AU  - Lazarević-Pašti, Tamara
AU  - Nastasijević, Branislav J.
AU  - Tanović, Brankica B.
AU  - Gašić, Slavica M.
AU  - Vasić, Vesna M.
PY  - 2019
UR  - https://linkinghub.elsevier.com/retrieve/pii/S0308814618313670
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/7821
AB  - UV-C irradiation is widely used in the food industry. However, the health effects from dietary exposure to the irradiated pesticide residues retained in foodstuffs are underestimated. In this study, technical chlorpyrifos (TCPF) and its oil in water (EW) and emulsifiable concentrate (EC) formulations were irradiated by UV-C, and their photodegradation products were subjected to toxicity assessment, including determination of acetylcholinesterase (AChE) activity, genotoxicity and oxidative stress using human blood cells as a model system. Toxicity studies were performed using the chlorpyrifos concentrations in the range of those proposed as the maximum residue levels in plant commodities. TCPF, EW and EC photodegradation products induced DNA damage and oxidative stress, and their genotoxicity did not decrease as a function of irradiation time. Irradiated TCPF and EC are more potent AChE inhibitors than irradiated EW. Accordingly, the application of UV-C irradiation must be considered when processing the plants previously treated with chlorpyrifos formulations. © 2018 Elsevier Ltd
T2  - Food Chemistry
T1  - UV-C light irradiation enhances toxic effects of chlorpyrifos and its formulations
VL  - 271
SP  - 469
EP  - 478
DO  - 10.1016/j.foodchem.2018.07.207
ER  - 

@article{
author = "Savić, Jasmina and Petrović, Sandra and Leskovac, Andreja and Lazarević-Pašti, Tamara and Nastasijević, Branislav J. and Tanović, Brankica B. and Gašić, Slavica M. and Vasić, Vesna M.",
year = "2019",
abstract = "UV-C irradiation is widely used in the food industry. However, the health effects from dietary exposure to the irradiated pesticide residues retained in foodstuffs are underestimated. In this study, technical chlorpyrifos (TCPF) and its oil in water (EW) and emulsifiable concentrate (EC) formulations were irradiated by UV-C, and their photodegradation products were subjected to toxicity assessment, including determination of acetylcholinesterase (AChE) activity, genotoxicity and oxidative stress using human blood cells as a model system. Toxicity studies were performed using the chlorpyrifos concentrations in the range of those proposed as the maximum residue levels in plant commodities. TCPF, EW and EC photodegradation products induced DNA damage and oxidative stress, and their genotoxicity did not decrease as a function of irradiation time. Irradiated TCPF and EC are more potent AChE inhibitors than irradiated EW. Accordingly, the application of UV-C irradiation must be considered when processing the plants previously treated with chlorpyrifos formulations. © 2018 Elsevier Ltd",
journal = "Food Chemistry",
title = "UV-C light irradiation enhances toxic effects of chlorpyrifos and its formulations",
volume = "271",
pages = "469-478",
doi = "10.1016/j.foodchem.2018.07.207"
}

Savić, J., Petrović, S., Leskovac, A., Lazarević-Pašti, T., Nastasijević, B. J., Tanović, B. B., Gašić, S. M.,& Vasić, V. M.. (2019). UV-C light irradiation enhances toxic effects of chlorpyrifos and its formulations. in Food Chemistry, 271, 469-478.
https://doi.org/10.1016/j.foodchem.2018.07.207

Savić J, Petrović S, Leskovac A, Lazarević-Pašti T, Nastasijević BJ, Tanović BB, Gašić SM, Vasić VM. UV-C light irradiation enhances toxic effects of chlorpyrifos and its formulations. in Food Chemistry. 2019;271:469-478.
doi:10.1016/j.foodchem.2018.07.207 .

Savić, Jasmina, Petrović, Sandra, Leskovac, Andreja, Lazarević-Pašti, Tamara, Nastasijević, Branislav J., Tanović, Brankica B., Gašić, Slavica M., Vasić, Vesna M., "UV-C light irradiation enhances toxic effects of chlorpyrifos and its formulations" in Food Chemistry, 271 (2019):469-478,
https://doi.org/10.1016/j.foodchem.2018.07.207 . .

TY  - DATA
AU  - Savić, Jasmina
AU  - Petrović, Sandra
AU  - Leskovac, Andreja
AU  - Lazarević-Pašti, Tamara
AU  - Nastasijević, Branislav J.
AU  - Tanović, Brankica B.
AU  - Gašić, Slavica M.
AU  - Vasić, Vesna M.
PY  - 2019
UR  - https://linkinghub.elsevier.com/retrieve/pii/S0308814618313670
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/7831
AB  - Supplementary data 1: Table 1S. The chromatographic gradient profile; Table 2S. CPF concentration decrease (corresponding initial CPF concentration decrease was set as 0%) for all three forms of CPF depending on irradiation time; Table 3S. CPF and CPO concentrations determined chromatographically for TCPF, EW and EC formulations, as the function of irradiation time; % of CPO comparing to initial CPF concentration in all three forms of CPF; 
Supplementary data 2: Material safety data sheet according to 1907/2006/EC, Article 31/version 1; 
Supplementary data 3: Material safety data sheet according to 1907/2006/EC, Article 31/version 4
T2  - Food Chemistry
T1  - Supplementary data: UV-C light irradiation enhances toxic effects of chlorpyrifos and its formulations
VL  - 271
SP  - 469
EP  - 478
DO  - 10.1016/j.foodchem.2018.07.207
ER  - 

@misc{
author = "Savić, Jasmina and Petrović, Sandra and Leskovac, Andreja and Lazarević-Pašti, Tamara and Nastasijević, Branislav J. and Tanović, Brankica B. and Gašić, Slavica M. and Vasić, Vesna M.",
year = "2019",
abstract = "Supplementary data 1: Table 1S. The chromatographic gradient profile; Table 2S. CPF concentration decrease (corresponding initial CPF concentration decrease was set as 0%) for all three forms of CPF depending on irradiation time; Table 3S. CPF and CPO concentrations determined chromatographically for TCPF, EW and EC formulations, as the function of irradiation time; % of CPO comparing to initial CPF concentration in all three forms of CPF; 
Supplementary data 2: Material safety data sheet according to 1907/2006/EC, Article 31/version 1; 
Supplementary data 3: Material safety data sheet according to 1907/2006/EC, Article 31/version 4",
journal = "Food Chemistry",
title = "Supplementary data: UV-C light irradiation enhances toxic effects of chlorpyrifos and its formulations",
volume = "271",
pages = "469-478",
doi = "10.1016/j.foodchem.2018.07.207"
}

Savić, J., Petrović, S., Leskovac, A., Lazarević-Pašti, T., Nastasijević, B. J., Tanović, B. B., Gašić, S. M.,& Vasić, V. M.. (2019). Supplementary data: UV-C light irradiation enhances toxic effects of chlorpyrifos and its formulations. in Food Chemistry, 271, 469-478.
https://doi.org/10.1016/j.foodchem.2018.07.207

Savić J, Petrović S, Leskovac A, Lazarević-Pašti T, Nastasijević BJ, Tanović BB, Gašić SM, Vasić VM. Supplementary data: UV-C light irradiation enhances toxic effects of chlorpyrifos and its formulations. in Food Chemistry. 2019;271:469-478.
doi:10.1016/j.foodchem.2018.07.207 .

Savić, Jasmina, Petrović, Sandra, Leskovac, Andreja, Lazarević-Pašti, Tamara, Nastasijević, Branislav J., Tanović, Brankica B., Gašić, Slavica M., Vasić, Vesna M., "Supplementary data: UV-C light irradiation enhances toxic effects of chlorpyrifos and its formulations" in Food Chemistry, 271 (2019):469-478,
https://doi.org/10.1016/j.foodchem.2018.07.207 . .

TY  - CONF
AU  - Marinković, Ana D.
AU  - Buha, Jovana Z.
AU  - Savić, Jasmina
AU  - Mladenović, Milica R.
AU  - Repić, Branislav
AU  - Nemoda, Stevan Đ.
PY  - 2019
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12777
AB  - Biomass combustion has many advantages compared to fossil fuels due to reduction of carbon dioxide emissions, but several issues are present during biomass combustion. One that must always be considered is emission of nitrogen oxides (NOx), which have significant impact on the environment and health. At biomass combustion, main mechanism responsible for NOx emission is oxidation of fuel-bound nitrogen. Increased NOx emissions are particularly present at agricultural biomass combustion, due to its increased nitrogen content, which is further expressed by the use of nitrogen fertilizer. Denitrification methods are classified as pre-combustion, combustion control and post-combustion (flue gas treatment) methods. Aim of this paper is to provide insight in different flue gas denitrification methods (DeNOx measures) from the review of existing literature, with emphasis on post-combustion methods, since they have higher efficiency. Also, pre-combustion and combustion control methods at agricultural biomass combustion often do not provide reduction below emission standards. Selective catalytic (SCR) and selective noncatalytic reduction (SNCR), wet scrubbing, adsorption, electron beam, electrochemical method, non-thermal plasma and microbial approach were considered. For each method, mechanism of NOx reduction is given and discussed, alongside with efficiency that could be achieved. Overall comparison of advantages and disadvantages for these methods is provided. Further research of denitrification and optimization of described methods, to overcome NOx emission problem is required. Application of these methods in commercial use and increasing their efficiency, while solving cost and methods disadvantages, is key for biomass to be used as a renewable energy source and fossil fuel replacement.
PB  - Niš : University of Niš, Faculty of Mechanical Engineering
C3  - 19th Conference on Thermal Science and Engineering of Serbia with the accompanying exhibition of equipment and achievements : Proceedings
T1  - Determination of polycyclic aromatic hydrocarbons in biomass ash from cigar burner combustion systems
SP  - 420
EP  - 430
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12777
ER  - 

@conference{
author = "Marinković, Ana D. and Buha, Jovana Z. and Savić, Jasmina and Mladenović, Milica R. and Repić, Branislav and Nemoda, Stevan Đ.",
year = "2019",
abstract = "Biomass combustion has many advantages compared to fossil fuels due to reduction of carbon dioxide emissions, but several issues are present during biomass combustion. One that must always be considered is emission of nitrogen oxides (NOx), which have significant impact on the environment and health. At biomass combustion, main mechanism responsible for NOx emission is oxidation of fuel-bound nitrogen. Increased NOx emissions are particularly present at agricultural biomass combustion, due to its increased nitrogen content, which is further expressed by the use of nitrogen fertilizer. Denitrification methods are classified as pre-combustion, combustion control and post-combustion (flue gas treatment) methods. Aim of this paper is to provide insight in different flue gas denitrification methods (DeNOx measures) from the review of existing literature, with emphasis on post-combustion methods, since they have higher efficiency. Also, pre-combustion and combustion control methods at agricultural biomass combustion often do not provide reduction below emission standards. Selective catalytic (SCR) and selective noncatalytic reduction (SNCR), wet scrubbing, adsorption, electron beam, electrochemical method, non-thermal plasma and microbial approach were considered. For each method, mechanism of NOx reduction is given and discussed, alongside with efficiency that could be achieved. Overall comparison of advantages and disadvantages for these methods is provided. Further research of denitrification and optimization of described methods, to overcome NOx emission problem is required. Application of these methods in commercial use and increasing their efficiency, while solving cost and methods disadvantages, is key for biomass to be used as a renewable energy source and fossil fuel replacement.",
publisher = "Niš : University of Niš, Faculty of Mechanical Engineering",
journal = "19th Conference on Thermal Science and Engineering of Serbia with the accompanying exhibition of equipment and achievements : Proceedings",
title = "Determination of polycyclic aromatic hydrocarbons in biomass ash from cigar burner combustion systems",
pages = "420-430",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12777"
}

Marinković, A. D., Buha, J. Z., Savić, J., Mladenović, M. R., Repić, B.,& Nemoda, S. Đ.. (2019). Determination of polycyclic aromatic hydrocarbons in biomass ash from cigar burner combustion systems. in 19th Conference on Thermal Science and Engineering of Serbia with the accompanying exhibition of equipment and achievements : Proceedings
Niš : University of Niš, Faculty of Mechanical Engineering., 420-430.
https://hdl.handle.net/21.15107/rcub_vinar_12777

Marinković AD, Buha JZ, Savić J, Mladenović MR, Repić B, Nemoda SĐ. Determination of polycyclic aromatic hydrocarbons in biomass ash from cigar burner combustion systems. in 19th Conference on Thermal Science and Engineering of Serbia with the accompanying exhibition of equipment and achievements : Proceedings. 2019;:420-430.
https://hdl.handle.net/21.15107/rcub_vinar_12777 .

Marinković, Ana D., Buha, Jovana Z., Savić, Jasmina, Mladenović, Milica R., Repić, Branislav, Nemoda, Stevan Đ., "Determination of polycyclic aromatic hydrocarbons in biomass ash from cigar burner combustion systems" in 19th Conference on Thermal Science and Engineering of Serbia with the accompanying exhibition of equipment and achievements : Proceedings (2019):420-430,
https://hdl.handle.net/21.15107/rcub_vinar_12777 .

TY  - CONF
AU  - Samolov, Aleksandra
AU  - Savić, Jasmina
AU  - Rajčić, Boris
AU  - Milovanović, Dubravka
PY  - 2019
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/11783
AB  - Diffuse reflection as a feature of dyed coatings is important characteristic regarding camouflage protection analysis. In our laboratory practice, the need for diffuse reflection analysis of textile materials has appeared, recently. Therefore, astm e903-12 [1] method has been modified in order to be applicable for this type of materials. The measurements of diffuse reflection were conducted, in the military technical institute laboratory for textile, leather and shoes examination in belgrade, serbia, using the uv/vis/nir spectrophotometer uv 3600 from a japanese manufacturer shimadzu with an integrating sphere within wavelength area from 650 nm to 1000 nm. For the purpose of results analyses, uv probe programme package [2] was used. 10 measurements of spectralon (manufactured by labsphere®), which is used as a certified reflectance standard, were performed and obtained standard deviation was 0.07 %. Then control sample, a piece of a standard military cloth of serbian army, which has five color shades (light green, beige green, dark green, brown and black) was tested. Standard deviations were in range from 0.09% for black tone on 650 nm wavelength to 2.0% for light green tone on 1000 nm. The combine uncertainty for the method was ±2.0 %, which coincides with the above mentioned astm standard. In the end, comparative measurements of the same control sample for all five shades were performed in the “vinca” institute for nuclear sciences, department for physical chemistry, university of belgrade on lambda 35 perkin-elmer uv/vis/nir spectrophotometer. Moreover, the z score was calculated as well, and its values ranged from -0.71 to +0.71, which was satisfying regarding interlaboratory measurements rules. Overall results showed that this method is applicable for diffuse reflection measurements of textile materials.
C3  - AUTEX2019 : 19th World Textile Conference on Textiles at the Crossroads, the book of abstracts; June 11-15, Ghent, Belgium
T1  - Validation Estimation of Diffuse Reflection Method for Textile Materials Analysis
SP  - 217
EP  - 217
UR  - https://hdl.handle.net/21.15107/rcub_vinar_11783
ER  - 

@conference{
author = "Samolov, Aleksandra and Savić, Jasmina and Rajčić, Boris and Milovanović, Dubravka",
year = "2019",
abstract = "Diffuse reflection as a feature of dyed coatings is important characteristic regarding camouflage protection analysis. In our laboratory practice, the need for diffuse reflection analysis of textile materials has appeared, recently. Therefore, astm e903-12 [1] method has been modified in order to be applicable for this type of materials. The measurements of diffuse reflection were conducted, in the military technical institute laboratory for textile, leather and shoes examination in belgrade, serbia, using the uv/vis/nir spectrophotometer uv 3600 from a japanese manufacturer shimadzu with an integrating sphere within wavelength area from 650 nm to 1000 nm. For the purpose of results analyses, uv probe programme package [2] was used. 10 measurements of spectralon (manufactured by labsphere®), which is used as a certified reflectance standard, were performed and obtained standard deviation was 0.07 %. Then control sample, a piece of a standard military cloth of serbian army, which has five color shades (light green, beige green, dark green, brown and black) was tested. Standard deviations were in range from 0.09% for black tone on 650 nm wavelength to 2.0% for light green tone on 1000 nm. The combine uncertainty for the method was ±2.0 %, which coincides with the above mentioned astm standard. In the end, comparative measurements of the same control sample for all five shades were performed in the “vinca” institute for nuclear sciences, department for physical chemistry, university of belgrade on lambda 35 perkin-elmer uv/vis/nir spectrophotometer. Moreover, the z score was calculated as well, and its values ranged from -0.71 to +0.71, which was satisfying regarding interlaboratory measurements rules. Overall results showed that this method is applicable for diffuse reflection measurements of textile materials.",
journal = "AUTEX2019 : 19th World Textile Conference on Textiles at the Crossroads, the book of abstracts; June 11-15, Ghent, Belgium",
title = "Validation Estimation of Diffuse Reflection Method for Textile Materials Analysis",
pages = "217-217",
url = "https://hdl.handle.net/21.15107/rcub_vinar_11783"
}

Samolov, A., Savić, J., Rajčić, B.,& Milovanović, D.. (2019). Validation Estimation of Diffuse Reflection Method for Textile Materials Analysis. in AUTEX2019 : 19th World Textile Conference on Textiles at the Crossroads, the book of abstracts; June 11-15, Ghent, Belgium, 217-217.
https://hdl.handle.net/21.15107/rcub_vinar_11783

Samolov A, Savić J, Rajčić B, Milovanović D. Validation Estimation of Diffuse Reflection Method for Textile Materials Analysis. in AUTEX2019 : 19th World Textile Conference on Textiles at the Crossroads, the book of abstracts; June 11-15, Ghent, Belgium. 2019;:217-217.
https://hdl.handle.net/21.15107/rcub_vinar_11783 .

Samolov, Aleksandra, Savić, Jasmina, Rajčić, Boris, Milovanović, Dubravka, "Validation Estimation of Diffuse Reflection Method for Textile Materials Analysis" in AUTEX2019 : 19th World Textile Conference on Textiles at the Crossroads, the book of abstracts; June 11-15, Ghent, Belgium (2019):217-217,
https://hdl.handle.net/21.15107/rcub_vinar_11783 .

TY  - JOUR
AU  - Janošević, Valentina
AU  - Mitrić, Miodrag
AU  - Savić, Jasmina
AU  - Validžić, Ivana Lj.
PY  - 2016
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/957
AB  - One of the intermediate steps in the organo-colloidal synthesis of crystalline Sb2S3 is a synthesis of spherical amorphous Sb2S3. In order to prove that the synthesized semiconductor can be considered an absorbing material for a solar device, the electronic and photovoltage properties of the amorphized and polycrystalline Sb2S3 thin films deposited by synthesized amorphous nanoparticles were studied. Optical studies revealed that the direct band gap energy was 1.65 eV and, two direct allowed transition of 1.57 and 1.91 eV for polycrystalline and amorphized thin films, respectively. The PL spectra of Sb2S3 showed an emission peak at 1.65 eV for both films. In order to obtain current-voltage (I-V) characteristics, two cells based on the Sb2S3 thin films as both an absorbing material and an electrolyte were designed and made. The observed Sb2S3 thin films, with a thickness of around 10 mu m, are of p-type. The exponential growth of the I-V curves reveals that the cells can work as a generator of electricity. (C) The Minerals, Metals and Materials Society and ASM International 2015
PB  - Springer
T2  - Metallurgical and Materials Transactions. A: Physical Metallurgy and Materials Science
T1  - Structural, Optical, and Electrical Properties of Applied Amorphized and Polycrystalline Sb2S3 Thin Films
VL  - 47A
IS  - 3
SP  - 1460
EP  - 1468
DO  - 10.1007/s11661-015-3282-9
ER  - 

@article{
author = "Janošević, Valentina and Mitrić, Miodrag and Savić, Jasmina and Validžić, Ivana Lj.",
year = "2016",
abstract = "One of the intermediate steps in the organo-colloidal synthesis of crystalline Sb2S3 is a synthesis of spherical amorphous Sb2S3. In order to prove that the synthesized semiconductor can be considered an absorbing material for a solar device, the electronic and photovoltage properties of the amorphized and polycrystalline Sb2S3 thin films deposited by synthesized amorphous nanoparticles were studied. Optical studies revealed that the direct band gap energy was 1.65 eV and, two direct allowed transition of 1.57 and 1.91 eV for polycrystalline and amorphized thin films, respectively. The PL spectra of Sb2S3 showed an emission peak at 1.65 eV for both films. In order to obtain current-voltage (I-V) characteristics, two cells based on the Sb2S3 thin films as both an absorbing material and an electrolyte were designed and made. The observed Sb2S3 thin films, with a thickness of around 10 mu m, are of p-type. The exponential growth of the I-V curves reveals that the cells can work as a generator of electricity. (C) The Minerals, Metals and Materials Society and ASM International 2015",
publisher = "Springer",
journal = "Metallurgical and Materials Transactions. A: Physical Metallurgy and Materials Science",
title = "Structural, Optical, and Electrical Properties of Applied Amorphized and Polycrystalline Sb2S3 Thin Films",
volume = "47A",
number = "3",
pages = "1460-1468",
doi = "10.1007/s11661-015-3282-9"
}

Janošević, V., Mitrić, M., Savić, J.,& Validžić, I. Lj.. (2016). Structural, Optical, and Electrical Properties of Applied Amorphized and Polycrystalline Sb2S3 Thin Films. in Metallurgical and Materials Transactions. A: Physical Metallurgy and Materials Science
Springer., 47A(3), 1460-1468.
https://doi.org/10.1007/s11661-015-3282-9

Janošević V, Mitrić M, Savić J, Validžić IL. Structural, Optical, and Electrical Properties of Applied Amorphized and Polycrystalline Sb2S3 Thin Films. in Metallurgical and Materials Transactions. A: Physical Metallurgy and Materials Science. 2016;47A(3):1460-1468.
doi:10.1007/s11661-015-3282-9 .

Janošević, Valentina, Mitrić, Miodrag, Savić, Jasmina, Validžić, Ivana Lj., "Structural, Optical, and Electrical Properties of Applied Amorphized and Polycrystalline Sb2S3 Thin Films" in Metallurgical and Materials Transactions. A: Physical Metallurgy and Materials Science, 47A, no. 3 (2016):1460-1468,
https://doi.org/10.1007/s11661-015-3282-9 . .

TY  - JOUR
AU  - Pjević, Dejan J.
AU  - Marinković, Tijana
AU  - Savić, Jasmina
AU  - Bundaleski, Nenad
AU  - Obradović, Marko O.
AU  - Milosavljević, Momir
AU  - Kulik, M.
PY  - 2015
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/7079
AB  - The influence of deposition and post-deposition annealing parameters on the structure and optical properties of TiO2 thin films synthesized by reactive e-beam evaporation is reported. Pure Ti (99.9%) was evaporated in oxygen atmosphere to form thin films on Si (100) and glass substrates. Depositions were conducted on substrates held at room temperature and at 200-400 degrees C heated substrates. Post-deposition annealing was done for 3 h at 500 degrees C in air. Compositional and structural studies were performed by Rutherford backscattering spectrometry, X-ray diffraction, and X-ray photoelectron spectroscopy, and optical properties were studied by ultraviolet-visible spectroscopy and analytically by pointwise unconstrained minimization approach method. It was found that both the structure and optical properties of the films are strongly influenced by the deposition and processing parameters. All deposited samples showed good stoichiometry of Ti:O similar to 1:2. Depending on the substrate temperature and oxygen pressure in the chamber during the deposition, anatase-rutile mixed films were obtained, and in some cases TiO and Ti2O3 phases were observed. Substrate deposition temperature appears to play the major role on the final structure of the films, while post-deposition annealing adds up for the lack of oxygen in some cases and invokes crystal grain growth of already initiated phases. The results can be interesting towards the development of TiO2 thin films with defined structure and optical properties. (C) 2015 Elsevier B.V. All rights reserved.
T2  - Thin Solid Films
T1  - Influence of substrate temperature and annealing on structural and optical properties of TiO2 films deposited by reactive e-beam evaporation
VL  - 591
SP  - 224
EP  - 229
DO  - 10.1016/j.tsf.2015.03.012
ER  - 

@article{
author = "Pjević, Dejan J. and Marinković, Tijana and Savić, Jasmina and Bundaleski, Nenad and Obradović, Marko O. and Milosavljević, Momir and Kulik, M.",
year = "2015",
abstract = "The influence of deposition and post-deposition annealing parameters on the structure and optical properties of TiO2 thin films synthesized by reactive e-beam evaporation is reported. Pure Ti (99.9%) was evaporated in oxygen atmosphere to form thin films on Si (100) and glass substrates. Depositions were conducted on substrates held at room temperature and at 200-400 degrees C heated substrates. Post-deposition annealing was done for 3 h at 500 degrees C in air. Compositional and structural studies were performed by Rutherford backscattering spectrometry, X-ray diffraction, and X-ray photoelectron spectroscopy, and optical properties were studied by ultraviolet-visible spectroscopy and analytically by pointwise unconstrained minimization approach method. It was found that both the structure and optical properties of the films are strongly influenced by the deposition and processing parameters. All deposited samples showed good stoichiometry of Ti:O similar to 1:2. Depending on the substrate temperature and oxygen pressure in the chamber during the deposition, anatase-rutile mixed films were obtained, and in some cases TiO and Ti2O3 phases were observed. Substrate deposition temperature appears to play the major role on the final structure of the films, while post-deposition annealing adds up for the lack of oxygen in some cases and invokes crystal grain growth of already initiated phases. The results can be interesting towards the development of TiO2 thin films with defined structure and optical properties. (C) 2015 Elsevier B.V. All rights reserved.",
journal = "Thin Solid Films",
title = "Influence of substrate temperature and annealing on structural and optical properties of TiO2 films deposited by reactive e-beam evaporation",
volume = "591",
pages = "224-229",
doi = "10.1016/j.tsf.2015.03.012"
}

Pjević, D. J., Marinković, T., Savić, J., Bundaleski, N., Obradović, M. O., Milosavljević, M.,& Kulik, M.. (2015). Influence of substrate temperature and annealing on structural and optical properties of TiO2 films deposited by reactive e-beam evaporation. in Thin Solid Films, 591, 224-229.
https://doi.org/10.1016/j.tsf.2015.03.012

Pjević DJ, Marinković T, Savić J, Bundaleski N, Obradović MO, Milosavljević M, Kulik M. Influence of substrate temperature and annealing on structural and optical properties of TiO2 films deposited by reactive e-beam evaporation. in Thin Solid Films. 2015;591:224-229.
doi:10.1016/j.tsf.2015.03.012 .

Pjević, Dejan J., Marinković, Tijana, Savić, Jasmina, Bundaleski, Nenad, Obradović, Marko O., Milosavljević, Momir, Kulik, M., "Influence of substrate temperature and annealing on structural and optical properties of TiO2 films deposited by reactive e-beam evaporation" in Thin Solid Films, 591 (2015):224-229,
https://doi.org/10.1016/j.tsf.2015.03.012 . .

TY  - JOUR
AU  - Laketa, Danijela
AU  - Savić, Jasmina
AU  - Bjelobaba, Ivana
AU  - Lavrnja, Irene
AU  - Vasić, Vesna M.
AU  - Stojiljković, Mirjana
AU  - Nedeljković, Nadežda
PY  - 2015
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/385
AB  - Background: Cortical stab injury (CSI) induces changes in the activity, expression and cellular distribution of specific ectonucleotidases at the injury site. Also, several experimentally induced neuropathologies are associated with changes in soluble ectonucleotidase activities in the plasma and serum, whilst various insults to the brain alter purine compounds levels in cerebrospinal fluid, but also in serum, indicating that insults to the brain may induce alterations in nucleotides release and rate of their hydrolysis in the vascular system. Since adenine nucleotides and adenosine regulate diverse cellular functions in the vascular system, including vascular tone, platelet aggregation and inflammatory responses of lymphocytes and macrophages, alterations of ectonucleotidase activities in the vascular system may be relevant for the clinical outcome of the primary insult. Methods: We explored ectonucleotidase activities using specific enzyme assays and determined adenine nucleotides concentrations by the UPLC method in the rat serum after cortical stab injury. Results: At 4-h post-injury, ATP and AMP hydrolysis increased by about 60% and 40%, respectively, while phosphodiesterase activity remained unchanged. Also, at 4-h postinjury a marked decrease in ATP concentration and more than 2-fold increase in AMP concentration were recorded. Conclusions: CSI induces rapid up-regulation of nucleotide catabolizing soluble ectonucleotidases in rat serum, which leads to the observed shift in serum nucleotide levels. The results obtained imply that ectonucleotidases and adenine nucleotides participate in the communication between the brain and the vascular system in physiological and pathological conditions and thereby may be involved in the development of various human neuropathologies.
T2  - Journal of Medical Biochemistry
T1  - Brain Injury Alters Ectonucleotidase Activities and Adenine Nucleotide Levels in Rat Serum
VL  - 34
IS  - 2
SP  - 215
EP  - 222
DO  - 10.2478/jomb-2014-0025
ER  - 

@article{
author = "Laketa, Danijela and Savić, Jasmina and Bjelobaba, Ivana and Lavrnja, Irene and Vasić, Vesna M. and Stojiljković, Mirjana and Nedeljković, Nadežda",
year = "2015",
abstract = "Background: Cortical stab injury (CSI) induces changes in the activity, expression and cellular distribution of specific ectonucleotidases at the injury site. Also, several experimentally induced neuropathologies are associated with changes in soluble ectonucleotidase activities in the plasma and serum, whilst various insults to the brain alter purine compounds levels in cerebrospinal fluid, but also in serum, indicating that insults to the brain may induce alterations in nucleotides release and rate of their hydrolysis in the vascular system. Since adenine nucleotides and adenosine regulate diverse cellular functions in the vascular system, including vascular tone, platelet aggregation and inflammatory responses of lymphocytes and macrophages, alterations of ectonucleotidase activities in the vascular system may be relevant for the clinical outcome of the primary insult. Methods: We explored ectonucleotidase activities using specific enzyme assays and determined adenine nucleotides concentrations by the UPLC method in the rat serum after cortical stab injury. Results: At 4-h post-injury, ATP and AMP hydrolysis increased by about 60% and 40%, respectively, while phosphodiesterase activity remained unchanged. Also, at 4-h postinjury a marked decrease in ATP concentration and more than 2-fold increase in AMP concentration were recorded. Conclusions: CSI induces rapid up-regulation of nucleotide catabolizing soluble ectonucleotidases in rat serum, which leads to the observed shift in serum nucleotide levels. The results obtained imply that ectonucleotidases and adenine nucleotides participate in the communication between the brain and the vascular system in physiological and pathological conditions and thereby may be involved in the development of various human neuropathologies.",
journal = "Journal of Medical Biochemistry",
title = "Brain Injury Alters Ectonucleotidase Activities and Adenine Nucleotide Levels in Rat Serum",
volume = "34",
number = "2",
pages = "215-222",
doi = "10.2478/jomb-2014-0025"
}

Laketa, D., Savić, J., Bjelobaba, I., Lavrnja, I., Vasić, V. M., Stojiljković, M.,& Nedeljković, N.. (2015). Brain Injury Alters Ectonucleotidase Activities and Adenine Nucleotide Levels in Rat Serum. in Journal of Medical Biochemistry, 34(2), 215-222.
https://doi.org/10.2478/jomb-2014-0025

Laketa D, Savić J, Bjelobaba I, Lavrnja I, Vasić VM, Stojiljković M, Nedeljković N. Brain Injury Alters Ectonucleotidase Activities and Adenine Nucleotide Levels in Rat Serum. in Journal of Medical Biochemistry. 2015;34(2):215-222.
doi:10.2478/jomb-2014-0025 .

Laketa, Danijela, Savić, Jasmina, Bjelobaba, Ivana, Lavrnja, Irene, Vasić, Vesna M., Stojiljković, Mirjana, Nedeljković, Nadežda, "Brain Injury Alters Ectonucleotidase Activities and Adenine Nucleotide Levels in Rat Serum" in Journal of Medical Biochemistry, 34, no. 2 (2015):215-222,
https://doi.org/10.2478/jomb-2014-0025 . .

TY  - JOUR
AU  - Petrović, Voin
AU  - Petrović, Sandra
AU  - Joksić, Gordana
AU  - Savić, Jasmina
AU  - Čolović, Mirjana B.
AU  - Cinellu, Maria Agostina
AU  - Massai, Lara
AU  - Messori, Luigi
AU  - Vasić, Vesna M.
PY  - 2014
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/140
AB  - Na+/K+-ATPase is in charge of maintaining the ionic and osmotic intracellular balance by using ATP as an energy source to drive excess Na+ ions out of the cell in exchange for K+ ions. We explored whether three representative cytotoxic gold(III) compounds might interfere with Na+/K+-ATPase and cause its inhibition at pharmacologically relevant concentrations. The tested complexes were [Au(bipy)(OH)(2)][PF6] (bipy = 2,2-bipyridine), [Au (py(dmb)-H)(CH3COO)(2)] (py(dmb)-H = deprotonated 6-(1,1-dimethylbenzyl)-pyridine), and [Au(bipy(dmb)-H)(OH)][PF6] (bipy(dmb)-H = deprotonated 6-(1,1-dimethylbenzyl)-2,2-bipyridine). We found that all of them caused a pronounced and similar inhibition of Na+/K+-ATPase activity. Inhibition was found to be non-competitive and reversible. Remarkably, treatment with cysteine resulted in reversal or prevention of Na+/K+-ATPase inhibition. It is very likely that the described effects may contribute to the overall cytotoxic profile of these gold complexes. (C) 2014 Elsevier Inc. All rights reserved.
T2  - Journal of Inorganic Biochemistry
T1  - Inhibition of Na+/K+-ATPase and cytotoxicity of a few selected gold(III) complexes
VL  - 140
SP  - 228
EP  - 235
DO  - 10.1016/j.jinorgbio.2014.07.015
ER  - 

@article{
author = "Petrović, Voin and Petrović, Sandra and Joksić, Gordana and Savić, Jasmina and Čolović, Mirjana B. and Cinellu, Maria Agostina and Massai, Lara and Messori, Luigi and Vasić, Vesna M.",
year = "2014",
abstract = "Na+/K+-ATPase is in charge of maintaining the ionic and osmotic intracellular balance by using ATP as an energy source to drive excess Na+ ions out of the cell in exchange for K+ ions. We explored whether three representative cytotoxic gold(III) compounds might interfere with Na+/K+-ATPase and cause its inhibition at pharmacologically relevant concentrations. The tested complexes were [Au(bipy)(OH)(2)][PF6] (bipy = 2,2-bipyridine), [Au (py(dmb)-H)(CH3COO)(2)] (py(dmb)-H = deprotonated 6-(1,1-dimethylbenzyl)-pyridine), and [Au(bipy(dmb)-H)(OH)][PF6] (bipy(dmb)-H = deprotonated 6-(1,1-dimethylbenzyl)-2,2-bipyridine). We found that all of them caused a pronounced and similar inhibition of Na+/K+-ATPase activity. Inhibition was found to be non-competitive and reversible. Remarkably, treatment with cysteine resulted in reversal or prevention of Na+/K+-ATPase inhibition. It is very likely that the described effects may contribute to the overall cytotoxic profile of these gold complexes. (C) 2014 Elsevier Inc. All rights reserved.",
journal = "Journal of Inorganic Biochemistry",
title = "Inhibition of Na+/K+-ATPase and cytotoxicity of a few selected gold(III) complexes",
volume = "140",
pages = "228-235",
doi = "10.1016/j.jinorgbio.2014.07.015"
}

Petrović, V., Petrović, S., Joksić, G., Savić, J., Čolović, M. B., Cinellu, M. A., Massai, L., Messori, L.,& Vasić, V. M.. (2014). Inhibition of Na+/K+-ATPase and cytotoxicity of a few selected gold(III) complexes. in Journal of Inorganic Biochemistry, 140, 228-235.
https://doi.org/10.1016/j.jinorgbio.2014.07.015

Petrović V, Petrović S, Joksić G, Savić J, Čolović MB, Cinellu MA, Massai L, Messori L, Vasić VM. Inhibition of Na+/K+-ATPase and cytotoxicity of a few selected gold(III) complexes. in Journal of Inorganic Biochemistry. 2014;140:228-235.
doi:10.1016/j.jinorgbio.2014.07.015 .

Petrović, Voin, Petrović, Sandra, Joksić, Gordana, Savić, Jasmina, Čolović, Mirjana B., Cinellu, Maria Agostina, Massai, Lara, Messori, Luigi, Vasić, Vesna M., "Inhibition of Na+/K+-ATPase and cytotoxicity of a few selected gold(III) complexes" in Journal of Inorganic Biochemistry, 140 (2014):228-235,
https://doi.org/10.1016/j.jinorgbio.2014.07.015 . .

TY  - JOUR
AU  - Lazarević-Pašti, Tamara
AU  - Čolović, Mirjana B.
AU  - Savić, Jasmina
AU  - Momić, Tatjana
AU  - Vasić, Vesna M.
PY  - 2011
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/4332
AB  - The aim of the work was to investigate the in vitro oxidation of diazinon and malathion, organophosphorous pesticides (OPs) containing phosphorthioate group, catalyzed by enzyme myeloperoxidase (MPO). The oxidation was performed in the presence of hydrogen peroxide. The products were identified as oxon derivatives (phosphates), where the sulfur atom from thioate group was substituted by an oxygen atom. No hydrolysis products were detected after enzyme - induced oxidation. The oxidation efficiency was controlled using acethylcholinesterase (AChE) bioassay for determination of oxon derivatives concentration. The influence of OPs concentration, incubation time of OPs with MPO, as well as MPO concentration on the yield of oxo forms was investigated. Kinetic constants of MPO in oxidation of malathion and diazinon were estimated. The maximum concentration of oxo forms was achieved after 10 min incubation of OPs in 50 mM phosphate buffer (pH 6.0) with 100 nM MPO. (C) 2011 Elsevier Inc. All rights reserved.
T2  - Pesticide Biochemistry and Physiology
T1  - Oxidation of diazinon and malathion by myeloperoxidase
VL  - 100
IS  - 2
SP  - 140
EP  - 144
DO  - 10.1016/j.pestbp.2011.03.001
ER  - 

@article{
author = "Lazarević-Pašti, Tamara and Čolović, Mirjana B. and Savić, Jasmina and Momić, Tatjana and Vasić, Vesna M.",
year = "2011",
abstract = "The aim of the work was to investigate the in vitro oxidation of diazinon and malathion, organophosphorous pesticides (OPs) containing phosphorthioate group, catalyzed by enzyme myeloperoxidase (MPO). The oxidation was performed in the presence of hydrogen peroxide. The products were identified as oxon derivatives (phosphates), where the sulfur atom from thioate group was substituted by an oxygen atom. No hydrolysis products were detected after enzyme - induced oxidation. The oxidation efficiency was controlled using acethylcholinesterase (AChE) bioassay for determination of oxon derivatives concentration. The influence of OPs concentration, incubation time of OPs with MPO, as well as MPO concentration on the yield of oxo forms was investigated. Kinetic constants of MPO in oxidation of malathion and diazinon were estimated. The maximum concentration of oxo forms was achieved after 10 min incubation of OPs in 50 mM phosphate buffer (pH 6.0) with 100 nM MPO. (C) 2011 Elsevier Inc. All rights reserved.",
journal = "Pesticide Biochemistry and Physiology",
title = "Oxidation of diazinon and malathion by myeloperoxidase",
volume = "100",
number = "2",
pages = "140-144",
doi = "10.1016/j.pestbp.2011.03.001"
}

Lazarević-Pašti, T., Čolović, M. B., Savić, J., Momić, T.,& Vasić, V. M.. (2011). Oxidation of diazinon and malathion by myeloperoxidase. in Pesticide Biochemistry and Physiology, 100(2), 140-144.
https://doi.org/10.1016/j.pestbp.2011.03.001

Lazarević-Pašti T, Čolović MB, Savić J, Momić T, Vasić VM. Oxidation of diazinon and malathion by myeloperoxidase. in Pesticide Biochemistry and Physiology. 2011;100(2):140-144.
doi:10.1016/j.pestbp.2011.03.001 .

Lazarević-Pašti, Tamara, Čolović, Mirjana B., Savić, Jasmina, Momić, Tatjana, Vasić, Vesna M., "Oxidation of diazinon and malathion by myeloperoxidase" in Pesticide Biochemistry and Physiology, 100, no. 2 (2011):140-144,
https://doi.org/10.1016/j.pestbp.2011.03.001 . .

TY  - JOUR
AU  - Čolović, Mirjana B.
AU  - Krstić, Danijela Z.
AU  - Petrović, Sandra
AU  - Leskovac, Andreja
AU  - Joksić, Gordana
AU  - Savić, Jasmina
AU  - Franko, Mladen
AU  - Trebše, Polonca
AU  - Vasić, Vesna M.
PY  - 2010
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3931
AB  - The toxic effects of diazinon and its irradiated Solutions were investigated using cultivated human blood cells (lymphocytes and erythrocytes) and skin fibroblasts. Ultra Performance Liquid Chromatography (UPLC)-UV/VIS system was used to monitor the disappearance of starting diazinon during 115-min photodegradation and formation of its by-products (diazoxon and 2-isopropyl-6-methyl-4-pyrimidinol (IMP)) as a function of time Dose-dependent AChE and Na+/K+-ATPase inhibition by diazinon was obtained for all investigated cells Calculated IC50 (72 h) values, in M, were 7 5 x 10(-6)/3 4 x 10(-5), 8.7 x 10(-5)/6.6 x 10(-5), and 3 0 x 10(-5)/4 6 x 10(-5) for fibroblast, erythrocyte and lymphocyte AChE/Na+/K+-ATPase, respectively. Results obtained for reference commercially purified target enzymes indicate similar sensitivity of AChE towards diazinon (IC50 (20 min)-7.8 x 10(-5) M). while diazinon concentrations below 10 mM did not noticeably affect Na+/K+-ATPase activity Besides, diazinon and IMP induced increasing incidence of micronuclei (via clastogenic mode of action) in a dose-dependent manner up to 2 x 10(-6) M and significant inhibition of cell proliferation and increased level of malondialdehyde at all investigated concentrations Although after 15-min diazinon irradiation formed products do not affect purified commercial enzymes activities, inhibitory effect of irradiated solutions on cell enzymes increased as a function of time exposure to UV light and resulted in significant reduction of AChE (LIP to 28-45%) and Na+/K+-ATPase (up to 35-40%) at the end of irradiation period Moreover, photodegradation treatment strengthened prooxidative properties of diazinon as well as its potency to induce cytogenetic damage (C) 2009 Elsevier Ireland Ltd All rights reserved.
T2  - Toxicology Letters
T1  - Toxic effects of diazinon and its photodegradation products
VL  - 193
IS  - 1
SP  - 9
EP  - 18
DO  - 10.1016/j.toxlet.2009.11.022
ER  - 

@article{
author = "Čolović, Mirjana B. and Krstić, Danijela Z. and Petrović, Sandra and Leskovac, Andreja and Joksić, Gordana and Savić, Jasmina and Franko, Mladen and Trebše, Polonca and Vasić, Vesna M.",
year = "2010",
abstract = "The toxic effects of diazinon and its irradiated Solutions were investigated using cultivated human blood cells (lymphocytes and erythrocytes) and skin fibroblasts. Ultra Performance Liquid Chromatography (UPLC)-UV/VIS system was used to monitor the disappearance of starting diazinon during 115-min photodegradation and formation of its by-products (diazoxon and 2-isopropyl-6-methyl-4-pyrimidinol (IMP)) as a function of time Dose-dependent AChE and Na+/K+-ATPase inhibition by diazinon was obtained for all investigated cells Calculated IC50 (72 h) values, in M, were 7 5 x 10(-6)/3 4 x 10(-5), 8.7 x 10(-5)/6.6 x 10(-5), and 3 0 x 10(-5)/4 6 x 10(-5) for fibroblast, erythrocyte and lymphocyte AChE/Na+/K+-ATPase, respectively. Results obtained for reference commercially purified target enzymes indicate similar sensitivity of AChE towards diazinon (IC50 (20 min)-7.8 x 10(-5) M). while diazinon concentrations below 10 mM did not noticeably affect Na+/K+-ATPase activity Besides, diazinon and IMP induced increasing incidence of micronuclei (via clastogenic mode of action) in a dose-dependent manner up to 2 x 10(-6) M and significant inhibition of cell proliferation and increased level of malondialdehyde at all investigated concentrations Although after 15-min diazinon irradiation formed products do not affect purified commercial enzymes activities, inhibitory effect of irradiated solutions on cell enzymes increased as a function of time exposure to UV light and resulted in significant reduction of AChE (LIP to 28-45%) and Na+/K+-ATPase (up to 35-40%) at the end of irradiation period Moreover, photodegradation treatment strengthened prooxidative properties of diazinon as well as its potency to induce cytogenetic damage (C) 2009 Elsevier Ireland Ltd All rights reserved.",
journal = "Toxicology Letters",
title = "Toxic effects of diazinon and its photodegradation products",
volume = "193",
number = "1",
pages = "9-18",
doi = "10.1016/j.toxlet.2009.11.022"
}

Čolović, M. B., Krstić, D. Z., Petrović, S., Leskovac, A., Joksić, G., Savić, J., Franko, M., Trebše, P.,& Vasić, V. M.. (2010). Toxic effects of diazinon and its photodegradation products. in Toxicology Letters, 193(1), 9-18.
https://doi.org/10.1016/j.toxlet.2009.11.022

Čolović MB, Krstić DZ, Petrović S, Leskovac A, Joksić G, Savić J, Franko M, Trebše P, Vasić VM. Toxic effects of diazinon and its photodegradation products. in Toxicology Letters. 2010;193(1):9-18.
doi:10.1016/j.toxlet.2009.11.022 .

Čolović, Mirjana B., Krstić, Danijela Z., Petrović, Sandra, Leskovac, Andreja, Joksić, Gordana, Savić, Jasmina, Franko, Mladen, Trebše, Polonca, Vasić, Vesna M., "Toxic effects of diazinon and its photodegradation products" in Toxicology Letters, 193, no. 1 (2010):9-18,
https://doi.org/10.1016/j.toxlet.2009.11.022 . .

TY  - JOUR
AU  - Petković, Marijana
AU  - Petrović, Biljana
AU  - Savić, Jasmina
AU  - Bugarčić, Živadin D.
AU  - Dimitrić-Marković, Jasmina
AU  - Momić, Tatjana
AU  - Vasić, Vesna M.
PY  - 2010
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3909
AB  - Matrix-assisted laser desorption and ionization time-of-flight mass spectrometry (MALDI-TOF MS) is a suitable method for the analysis of inorganic and organic compounds and biomolecules This makes. MALDI-TOF MS convenient for monitoring the interaction of metallo-drugs with biomolecules. Results presented in this manuscript demonstrate that flavonoids such as apigenin, kaempferol and luteolin are suitable for MALDI-TOF MS analysis of Pt(II), Pd(II), Pt(IV) and Ru(III) complexes, giving different signal-to-noise ratios of the analyte peak. The MALDI-TOF mass spectra of inorganic complexes acquired with these flavonoid matrices are easy to interpret and have some advantages over the application of other commonly used matrices: a low number of matrix peaks are detectable and the coordinative metal-ligand bond is, in most cases, preserved. On the other hand, flavonoids do not act as typical matrices, as their excess is not required for the acquisition of MALDI-TOF mass spectra of inorganic complexes. (C) 2009 Elsevier B.V. All rights reserved.
T2  - International Journal of Mass Spectrometry
T1  - Flavonoids as matrices for MALDI-TOF mass spectrometric analysis of transition metal complexes
VL  - 290
IS  - 1
SP  - 39
EP  - 46
DO  - 10.1016/j.ijms.2009.12.001
ER  - 

@article{
author = "Petković, Marijana and Petrović, Biljana and Savić, Jasmina and Bugarčić, Živadin D. and Dimitrić-Marković, Jasmina and Momić, Tatjana and Vasić, Vesna M.",
year = "2010",
abstract = "Matrix-assisted laser desorption and ionization time-of-flight mass spectrometry (MALDI-TOF MS) is a suitable method for the analysis of inorganic and organic compounds and biomolecules This makes. MALDI-TOF MS convenient for monitoring the interaction of metallo-drugs with biomolecules. Results presented in this manuscript demonstrate that flavonoids such as apigenin, kaempferol and luteolin are suitable for MALDI-TOF MS analysis of Pt(II), Pd(II), Pt(IV) and Ru(III) complexes, giving different signal-to-noise ratios of the analyte peak. The MALDI-TOF mass spectra of inorganic complexes acquired with these flavonoid matrices are easy to interpret and have some advantages over the application of other commonly used matrices: a low number of matrix peaks are detectable and the coordinative metal-ligand bond is, in most cases, preserved. On the other hand, flavonoids do not act as typical matrices, as their excess is not required for the acquisition of MALDI-TOF mass spectra of inorganic complexes. (C) 2009 Elsevier B.V. All rights reserved.",
journal = "International Journal of Mass Spectrometry",
title = "Flavonoids as matrices for MALDI-TOF mass spectrometric analysis of transition metal complexes",
volume = "290",
number = "1",
pages = "39-46",
doi = "10.1016/j.ijms.2009.12.001"
}

Petković, M., Petrović, B., Savić, J., Bugarčić, Ž. D., Dimitrić-Marković, J., Momić, T.,& Vasić, V. M.. (2010). Flavonoids as matrices for MALDI-TOF mass spectrometric analysis of transition metal complexes. in International Journal of Mass Spectrometry, 290(1), 39-46.
https://doi.org/10.1016/j.ijms.2009.12.001

Petković M, Petrović B, Savić J, Bugarčić ŽD, Dimitrić-Marković J, Momić T, Vasić VM. Flavonoids as matrices for MALDI-TOF mass spectrometric analysis of transition metal complexes. in International Journal of Mass Spectrometry. 2010;290(1):39-46.
doi:10.1016/j.ijms.2009.12.001 .

Petković, Marijana, Petrović, Biljana, Savić, Jasmina, Bugarčić, Živadin D., Dimitrić-Marković, Jasmina, Momić, Tatjana, Vasić, Vesna M., "Flavonoids as matrices for MALDI-TOF mass spectrometric analysis of transition metal complexes" in International Journal of Mass Spectrometry, 290, no. 1 (2010):39-46,
https://doi.org/10.1016/j.ijms.2009.12.001 . .

TY  - JOUR
AU  - Laketa, Danijela
AU  - Bjelobaba, Ivana
AU  - Savić, Jasmina
AU  - Lavrnja, Irena
AU  - Stojiljković, Mirjana
AU  - Rakić, Ljubisav
AU  - Nedeljković, Nadežda
PY  - 2010
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3996
AB  - Biochemical properties of nucleotide pyrophosphatase/phosphodiesterase (NPP) in rat serum have been described by assessing its nucleotide phosphodiesterase activity, using p-nitrophenyl-5-thymidine monophosphate (p-Nph-5-TMP) as a substrate. It was demonstrated that NPP activity shares some typical characteristics described for other soluble NPP, such as divalent cation dependence, strong alkaline pH optimum (pH 10.5), inhibition by glycosaminoglycans, and K (m) for p-Nph-5-TMP hydrolysis of 61.8 +/- A 5.2 mu M. In order to characterize the relation between phosphodiesterase and pyrophosphatase activities of NPP, we have analyzed the effects of different natural nucleotides and nucleotide analogs. ATP, ADP, and AMP competitively inhibited p-Nph-5-TMP hydrolysis with K (i) values ranging 13-43 mu M. Nucleotide analogs, alpha,beta-metATP, BzATP, 2-MeSATP, and dialATP behaved as competitive inhibitors, whereas alpha,beta-metADP induced mixed inhibition, with K (i) ranging from 2 to 20 mu M. Chromatographic analysis revealed that alpha,beta-metATP, BzATP, and 2-MeSATP were catalytically degraded in the serum, whereas dialATP and alpha,beta-metADP resisted hydrolysis, implying that the former act as substrates and the latter as true competitive inhibitors of serum NPP activity. Since NPP activity is involved in generation, breakdown, and recycling of extracellular adenine nucleotides in the vascular compartment, the results suggest that both hydrolyzable and non-hydrolyzable nucleotide analogs could alter the amplitude and direction of ATP actions and could have potential therapeutic application.
T2  - Molecular and Cellular Biochemistry
T1  - Biochemical characterization of soluble nucleotide pyrophosphatase/phosphodiesterase activity in rat serum
VL  - 339
IS  - 1-2
SP  - 99
EP  - 106
DO  - 10.1007/s11010-009-0373-1
ER  - 

@article{
author = "Laketa, Danijela and Bjelobaba, Ivana and Savić, Jasmina and Lavrnja, Irena and Stojiljković, Mirjana and Rakić, Ljubisav and Nedeljković, Nadežda",
year = "2010",
abstract = "Biochemical properties of nucleotide pyrophosphatase/phosphodiesterase (NPP) in rat serum have been described by assessing its nucleotide phosphodiesterase activity, using p-nitrophenyl-5-thymidine monophosphate (p-Nph-5-TMP) as a substrate. It was demonstrated that NPP activity shares some typical characteristics described for other soluble NPP, such as divalent cation dependence, strong alkaline pH optimum (pH 10.5), inhibition by glycosaminoglycans, and K (m) for p-Nph-5-TMP hydrolysis of 61.8 +/- A 5.2 mu M. In order to characterize the relation between phosphodiesterase and pyrophosphatase activities of NPP, we have analyzed the effects of different natural nucleotides and nucleotide analogs. ATP, ADP, and AMP competitively inhibited p-Nph-5-TMP hydrolysis with K (i) values ranging 13-43 mu M. Nucleotide analogs, alpha,beta-metATP, BzATP, 2-MeSATP, and dialATP behaved as competitive inhibitors, whereas alpha,beta-metADP induced mixed inhibition, with K (i) ranging from 2 to 20 mu M. Chromatographic analysis revealed that alpha,beta-metATP, BzATP, and 2-MeSATP were catalytically degraded in the serum, whereas dialATP and alpha,beta-metADP resisted hydrolysis, implying that the former act as substrates and the latter as true competitive inhibitors of serum NPP activity. Since NPP activity is involved in generation, breakdown, and recycling of extracellular adenine nucleotides in the vascular compartment, the results suggest that both hydrolyzable and non-hydrolyzable nucleotide analogs could alter the amplitude and direction of ATP actions and could have potential therapeutic application.",
journal = "Molecular and Cellular Biochemistry",
title = "Biochemical characterization of soluble nucleotide pyrophosphatase/phosphodiesterase activity in rat serum",
volume = "339",
number = "1-2",
pages = "99-106",
doi = "10.1007/s11010-009-0373-1"
}

Laketa, D., Bjelobaba, I., Savić, J., Lavrnja, I., Stojiljković, M., Rakić, L.,& Nedeljković, N.. (2010). Biochemical characterization of soluble nucleotide pyrophosphatase/phosphodiesterase activity in rat serum. in Molecular and Cellular Biochemistry, 339(1-2), 99-106.
https://doi.org/10.1007/s11010-009-0373-1

Laketa D, Bjelobaba I, Savić J, Lavrnja I, Stojiljković M, Rakić L, Nedeljković N. Biochemical characterization of soluble nucleotide pyrophosphatase/phosphodiesterase activity in rat serum. in Molecular and Cellular Biochemistry. 2010;339(1-2):99-106.
doi:10.1007/s11010-009-0373-1 .

Laketa, Danijela, Bjelobaba, Ivana, Savić, Jasmina, Lavrnja, Irena, Stojiljković, Mirjana, Rakić, Ljubisav, Nedeljković, Nadežda, "Biochemical characterization of soluble nucleotide pyrophosphatase/phosphodiesterase activity in rat serum" in Molecular and Cellular Biochemistry, 339, no. 1-2 (2010):99-106,
https://doi.org/10.1007/s11010-009-0373-1 . .

TY  - JOUR
AU  - Zavastin, Daniela
AU  - Cretescu, Igor
AU  - Bezdadea, Mariana
AU  - Bourceanu, Militina
AU  - Dragan, Maria
AU  - Lisa, Gabriela
AU  - Mangalagiu, Ionel
AU  - Vasić, Vesna M.
AU  - Savić, Jasmina
PY  - 2010
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/4140
AB  - The characteristics of blend membrane, prepared from cellulose acetate and polyurethane, were investigated in order to compare its properties with membrane material from pure cellulose acetate and polyurethane. Attenuation of total reflection Fourier transform infrared spectroscopy was utilised to investigate structural properties of membranes. Membranes morphology and its thermal properties were characterized by scanning electron microscopy and thermal analysis methods (thermogravimetric analysis, differential thermal analysis and derivated thermogravimetric analysis). Besides, swelling degree, membrane permeability, diameter of membrane pores, its thickness and stability as the function of pH of prepared blend membrane were determined. The applicability of prepared blend membrane was tested by using of aqueous solutions of new textile dye and its complex with iron(III) ions in order to test its suitability for wastewater treatment. (C) 2010 Elsevier B.V. All rights reserved.
T2  - Colloids and Surfaces. A: Physicochemical and Engineering Aspects
T1  - Preparation, characterization and applicability of cellulose acetate-polyurethane blend membrane in separation techniques
VL  - 370
IS  - 1-3
SP  - 120
EP  - 128
DO  - 10.1016/j.colsurfa.2010.08.058
ER  - 

@article{
author = "Zavastin, Daniela and Cretescu, Igor and Bezdadea, Mariana and Bourceanu, Militina and Dragan, Maria and Lisa, Gabriela and Mangalagiu, Ionel and Vasić, Vesna M. and Savić, Jasmina",
year = "2010",
abstract = "The characteristics of blend membrane, prepared from cellulose acetate and polyurethane, were investigated in order to compare its properties with membrane material from pure cellulose acetate and polyurethane. Attenuation of total reflection Fourier transform infrared spectroscopy was utilised to investigate structural properties of membranes. Membranes morphology and its thermal properties were characterized by scanning electron microscopy and thermal analysis methods (thermogravimetric analysis, differential thermal analysis and derivated thermogravimetric analysis). Besides, swelling degree, membrane permeability, diameter of membrane pores, its thickness and stability as the function of pH of prepared blend membrane were determined. The applicability of prepared blend membrane was tested by using of aqueous solutions of new textile dye and its complex with iron(III) ions in order to test its suitability for wastewater treatment. (C) 2010 Elsevier B.V. All rights reserved.",
journal = "Colloids and Surfaces. A: Physicochemical and Engineering Aspects",
title = "Preparation, characterization and applicability of cellulose acetate-polyurethane blend membrane in separation techniques",
volume = "370",
number = "1-3",
pages = "120-128",
doi = "10.1016/j.colsurfa.2010.08.058"
}

Zavastin, D., Cretescu, I., Bezdadea, M., Bourceanu, M., Dragan, M., Lisa, G., Mangalagiu, I., Vasić, V. M.,& Savić, J.. (2010). Preparation, characterization and applicability of cellulose acetate-polyurethane blend membrane in separation techniques. in Colloids and Surfaces. A: Physicochemical and Engineering Aspects, 370(1-3), 120-128.
https://doi.org/10.1016/j.colsurfa.2010.08.058

Zavastin D, Cretescu I, Bezdadea M, Bourceanu M, Dragan M, Lisa G, Mangalagiu I, Vasić VM, Savić J. Preparation, characterization and applicability of cellulose acetate-polyurethane blend membrane in separation techniques. in Colloids and Surfaces. A: Physicochemical and Engineering Aspects. 2010;370(1-3):120-128.
doi:10.1016/j.colsurfa.2010.08.058 .

Zavastin, Daniela, Cretescu, Igor, Bezdadea, Mariana, Bourceanu, Militina, Dragan, Maria, Lisa, Gabriela, Mangalagiu, Ionel, Vasić, Vesna M., Savić, Jasmina, "Preparation, characterization and applicability of cellulose acetate-polyurethane blend membrane in separation techniques" in Colloids and Surfaces. A: Physicochemical and Engineering Aspects, 370, no. 1-3 (2010):120-128,
https://doi.org/10.1016/j.colsurfa.2010.08.058 . .

TY  - JOUR
AU  - Čolović, Mirjana B.
AU  - Krstić, Danijela Z.
AU  - Krinulović, Katarina
AU  - Momić, Tatjana
AU  - Savić, Jasmina
AU  - Vujačić, Ana V.
AU  - Vasić, Vesna M.
PY  - 2009
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/6815
AB  - The aim of the study was to give an overview of the mechanism of inhibition of Na+/K+-ATPase activity induced by some specific and non specific inhibitors. For this purpose, the effects of some ouabain like compounds (digoxin, gitoxin), noble metals complexes ([PtCl2DMSO2], [AuCl4](-), [PdCl4](2-), [PdCl(dien)](+), [PdCl(Me(4)dien)](+)), transition metal ions (Cu2+, Zn2+, Fe2+, Co2+), and heavy metal ions (Hg2+, Pb2+, Cd2+) on the activity of Na+/K+-ATPase from rat synaptic plasma membranes (SPM), porcine cerebral cortex and human erythrocytes were discussed.
T2  - Russian Journal of Physical Chemistry A
T1  - Na+/K+-ATPase: Activity and inhibition
VL  - 83
IS  - 9
SP  - 1602
EP  - 1608
DO  - 10.1134/S0036024409090337
ER  - 

@article{
author = "Čolović, Mirjana B. and Krstić, Danijela Z. and Krinulović, Katarina and Momić, Tatjana and Savić, Jasmina and Vujačić, Ana V. and Vasić, Vesna M.",
year = "2009",
abstract = "The aim of the study was to give an overview of the mechanism of inhibition of Na+/K+-ATPase activity induced by some specific and non specific inhibitors. For this purpose, the effects of some ouabain like compounds (digoxin, gitoxin), noble metals complexes ([PtCl2DMSO2], [AuCl4](-), [PdCl4](2-), [PdCl(dien)](+), [PdCl(Me(4)dien)](+)), transition metal ions (Cu2+, Zn2+, Fe2+, Co2+), and heavy metal ions (Hg2+, Pb2+, Cd2+) on the activity of Na+/K+-ATPase from rat synaptic plasma membranes (SPM), porcine cerebral cortex and human erythrocytes were discussed.",
journal = "Russian Journal of Physical Chemistry A",
title = "Na+/K+-ATPase: Activity and inhibition",
volume = "83",
number = "9",
pages = "1602-1608",
doi = "10.1134/S0036024409090337"
}

Čolović, M. B., Krstić, D. Z., Krinulović, K., Momić, T., Savić, J., Vujačić, A. V.,& Vasić, V. M.. (2009). Na+/K+-ATPase: Activity and inhibition. in Russian Journal of Physical Chemistry A, 83(9), 1602-1608.
https://doi.org/10.1134/S0036024409090337

Čolović MB, Krstić DZ, Krinulović K, Momić T, Savić J, Vujačić AV, Vasić VM. Na+/K+-ATPase: Activity and inhibition. in Russian Journal of Physical Chemistry A. 2009;83(9):1602-1608.
doi:10.1134/S0036024409090337 .

Čolović, Mirjana B., Krstić, Danijela Z., Krinulović, Katarina, Momić, Tatjana, Savić, Jasmina, Vujačić, Ana V., Vasić, Vesna M., "Na+/K+-ATPase: Activity and inhibition" in Russian Journal of Physical Chemistry A, 83, no. 9 (2009):1602-1608,
https://doi.org/10.1134/S0036024409090337 . .

TY  - JOUR
AU  - Vasić, Dragana D.
AU  - Savić, Jasmina
AU  - Bugaricic, Zivadin
AU  - Krstić, Danijela Z.
AU  - Tomić, Nenad
AU  - Čolović, Mirjana B.
AU  - Petković, Marijana
AU  - Vasić, Vesna M.
PY  - 2009
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3657
AB  - The reaction between [PtCl,(DMSO)(2)] and L-cysteine (L-Cys) has been investigated in the presence of micelles of sodium dodecyl sulfate (SDS) - as a model for biological membranes. Additionally, the inhibitory effect of [PtCl2(DMSO)(2)] on the Na+,K+-ATPise activity and its partial prevention with 10 mM L-Cys were demonstrated. The interaction of L-Cys with [Ptcl(2)(DMSO)(2)] resulted in the formation of a [Pt(DMSO)(2)L-Cys)(2)](2+) (DMSO)(2)] Complex, which most probably occurs through stepwise replacement of Cl- with L-Cys. It has also been demonstrated that neither the pH value nor SDS affects the composition of the new complex. On the other hand, the pH value and SDS do affect the reaction rate, most probably due to electrostatic interactions with reactants. In Summary, this study can be used as a simple model approach for the investigation of reaction mechanisms between platinum complexes and various biomolecules, and for the determination of potential toxicity and/or side effects of antitumour platinum drugs.
T2  - Zeitschrift fur Naturforschung. Section C: Journal of Biosciences
T1  - Interaction of the [PtCl2(DMSO)(2)] Complex with L-Cysteine
VL  - 64
IS  - 1-2
SP  - 103
EP  - 108
DO  - 10.1515/znc-2009-1-217
UR  - https://hdl.handle.net/21.15107/rcub_vinar_3657
ER  - 

@article{
author = "Vasić, Dragana D. and Savić, Jasmina and Bugaricic, Zivadin and Krstić, Danijela Z. and Tomić, Nenad and Čolović, Mirjana B. and Petković, Marijana and Vasić, Vesna M.",
year = "2009",
abstract = "The reaction between [PtCl,(DMSO)(2)] and L-cysteine (L-Cys) has been investigated in the presence of micelles of sodium dodecyl sulfate (SDS) - as a model for biological membranes. Additionally, the inhibitory effect of [PtCl2(DMSO)(2)] on the Na+,K+-ATPise activity and its partial prevention with 10 mM L-Cys were demonstrated. The interaction of L-Cys with [Ptcl(2)(DMSO)(2)] resulted in the formation of a [Pt(DMSO)(2)L-Cys)(2)](2+) (DMSO)(2)] Complex, which most probably occurs through stepwise replacement of Cl- with L-Cys. It has also been demonstrated that neither the pH value nor SDS affects the composition of the new complex. On the other hand, the pH value and SDS do affect the reaction rate, most probably due to electrostatic interactions with reactants. In Summary, this study can be used as a simple model approach for the investigation of reaction mechanisms between platinum complexes and various biomolecules, and for the determination of potential toxicity and/or side effects of antitumour platinum drugs.",
journal = "Zeitschrift fur Naturforschung. Section C: Journal of Biosciences",
title = "Interaction of the [PtCl2(DMSO)(2)] Complex with L-Cysteine",
volume = "64",
number = "1-2",
pages = "103-108",
doi = "10.1515/znc-2009-1-217",
url = "https://hdl.handle.net/21.15107/rcub_vinar_3657"
}

Vasić, D. D., Savić, J., Bugaricic, Z., Krstić, D. Z., Tomić, N., Čolović, M. B., Petković, M.,& Vasić, V. M.. (2009). Interaction of the [PtCl2(DMSO)(2)] Complex with L-Cysteine. in Zeitschrift fur Naturforschung. Section C: Journal of Biosciences, 64(1-2), 103-108.
https://doi.org/10.1515/znc-2009-1-217
https://hdl.handle.net/21.15107/rcub_vinar_3657

Vasić DD, Savić J, Bugaricic Z, Krstić DZ, Tomić N, Čolović MB, Petković M, Vasić VM. Interaction of the [PtCl2(DMSO)(2)] Complex with L-Cysteine. in Zeitschrift fur Naturforschung. Section C: Journal of Biosciences. 2009;64(1-2):103-108.
doi:10.1515/znc-2009-1-217
https://hdl.handle.net/21.15107/rcub_vinar_3657 .

Vasić, Dragana D., Savić, Jasmina, Bugaricic, Zivadin, Krstić, Danijela Z., Tomić, Nenad, Čolović, Mirjana B., Petković, Marijana, Vasić, Vesna M., "Interaction of the [PtCl2(DMSO)(2)] Complex with L-Cysteine" in Zeitschrift fur Naturforschung. Section C: Journal of Biosciences, 64, no. 1-2 (2009):103-108,
https://doi.org/10.1515/znc-2009-1-217 .,
https://hdl.handle.net/21.15107/rcub_vinar_3657 .

TY  - JOUR
AU  - Cojocaru, Corneliu
AU  - Diaconu, Mariana
AU  - Cretescu, Igor
AU  - Savić, Jasmina
AU  - Vasić, Vesna M.
PY  - 2009
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3636
AB  - The ability of dried yeast Saccharomyces biomass to remove Cu(II) ions from aqueous solutions was investigated by using of batch techniques. The influence of different parameters on copper uptake by dried yeast, such as initial Cu(II) concentration, initial pH of solution and temperature, was studied. The Freundlich, Langmuir, Redlich-Peterson and Sips isotherms were applied to the obtained experimental data. According to Langmuir isotherm the maximum adsorption capacity of investigated non-living biomass was found to be 2.59 mg/g. The thermodynamic parameters (e.g. free energy and enthalpy) were calculated and discussed. The adsorption of Cu(II) onto the dried cells of Saccharomyces cerevisiae is an endothermic process and become more favorable with the increasing of temperature in pH range from 3 to 4. Optimization studies by means of response surface methodology were carried out, which resulted in improvement of the efficiency of sorption removal by using of biomass. The removal efficiency of real wastewater originating from electroplating industry which contains Sn(II) ions was determined and compared with synthetic wastewater obtained in laboratory. (C) 2008 Elsevier B.V. All rights reserved.
T2  - Colloids and Surfaces. A: Physicochemical and Engineering Aspects
T1  - Biosorption of copper(II) ions from aqua solutions using dried yeast biomass
VL  - 335
IS  - 1-3
SP  - 181
EP  - 188
DO  - 10.1016/j.colsurfa.2008.11.003
ER  - 

@article{
author = "Cojocaru, Corneliu and Diaconu, Mariana and Cretescu, Igor and Savić, Jasmina and Vasić, Vesna M.",
year = "2009",
abstract = "The ability of dried yeast Saccharomyces biomass to remove Cu(II) ions from aqueous solutions was investigated by using of batch techniques. The influence of different parameters on copper uptake by dried yeast, such as initial Cu(II) concentration, initial pH of solution and temperature, was studied. The Freundlich, Langmuir, Redlich-Peterson and Sips isotherms were applied to the obtained experimental data. According to Langmuir isotherm the maximum adsorption capacity of investigated non-living biomass was found to be 2.59 mg/g. The thermodynamic parameters (e.g. free energy and enthalpy) were calculated and discussed. The adsorption of Cu(II) onto the dried cells of Saccharomyces cerevisiae is an endothermic process and become more favorable with the increasing of temperature in pH range from 3 to 4. Optimization studies by means of response surface methodology were carried out, which resulted in improvement of the efficiency of sorption removal by using of biomass. The removal efficiency of real wastewater originating from electroplating industry which contains Sn(II) ions was determined and compared with synthetic wastewater obtained in laboratory. (C) 2008 Elsevier B.V. All rights reserved.",
journal = "Colloids and Surfaces. A: Physicochemical and Engineering Aspects",
title = "Biosorption of copper(II) ions from aqua solutions using dried yeast biomass",
volume = "335",
number = "1-3",
pages = "181-188",
doi = "10.1016/j.colsurfa.2008.11.003"
}

Cojocaru, C., Diaconu, M., Cretescu, I., Savić, J.,& Vasić, V. M.. (2009). Biosorption of copper(II) ions from aqua solutions using dried yeast biomass. in Colloids and Surfaces. A: Physicochemical and Engineering Aspects, 335(1-3), 181-188.
https://doi.org/10.1016/j.colsurfa.2008.11.003

Cojocaru C, Diaconu M, Cretescu I, Savić J, Vasić VM. Biosorption of copper(II) ions from aqua solutions using dried yeast biomass. in Colloids and Surfaces. A: Physicochemical and Engineering Aspects. 2009;335(1-3):181-188.
doi:10.1016/j.colsurfa.2008.11.003 .

Cojocaru, Corneliu, Diaconu, Mariana, Cretescu, Igor, Savić, Jasmina, Vasić, Vesna M., "Biosorption of copper(II) ions from aqua solutions using dried yeast biomass" in Colloids and Surfaces. A: Physicochemical and Engineering Aspects, 335, no. 1-3 (2009):181-188,
https://doi.org/10.1016/j.colsurfa.2008.11.003 . .