TY  - JOUR
AU  - Ražić, Slavica
AU  - Arsenijević, Jelena
AU  - Đogo Mračević, Svetlana
AU  - Mušović, Jasmina
AU  - Trtić-Petrović, Tatjana
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/11222
AB  - More environment-friendly solvents in analytical chemistry are almost inevitable in both sample preparation and analysis to meet the high standards of sustainable chemistry and human welfare. In this review paper, a critical look at the advantages and still unsolved problems of most potential classes of green solvents is presented to give an overview of the current state-of-the-art in this field. Replacing volatile organic compounds (VOCs) by ecofriendly and benign solvents in extractions/separations in sample preparation, as the most tedious and demanding step in analysis, is one of roads toward sustainable chemistry. Water under sub- and supercritical conditions, carbon-dioxide, ionic liquids (ILs), deep eutectic solvents (DESs), and those of natural origin (NADES) belong to the most promising classes of solvents in green analytical chemistry. Basic theory and mechanisms of their use illustrated by representative but not exhaustive list of examples related to complex matrices (environmental and natural food products) from analytical practice are presented in this review. Perspectives of QuEChERS, in line with GAC principles, are highlighted, in line with current trends of “going green” for quick, easy, cheap, effective, rugged, and safe analytical methods. Compliance with green chemistry (GC), especially green analytical chemistry (GAC) principles, is not a fashionable issue but, more the trend toward a sustainable future with greener chemistry; thus, green metrics are an unavoidable tool to measure how green the applied method or procedure is. Herein, the most common tools will be presented and discussed, such as national environmental method index (NEMI), analytical ecoscale, green analytical procedure index (GAPI), analytical greenness calculator (AGREE), complementary green analytical procedure index (ComplexGAPI), and analytical greenness metric for sample preparation (AGREEprep). The future trends for research and development in this still expanding field are presented in a critical view of advantages and disadvantages as well as improvement of the validation of analytical procedures. The creation of new certified reference materials (CRMs) and validated methods for specified analytes in complex matrices is a demanding task in the coming years. Tailor-made solvents with physicochemical properties for intended use are required for the selective extraction and separation and open numerous possibilities and huge potential for future research and industrial applications.
T2  - Analyst
T1  - Greener chemistry in analytical sciences: from green solvents to applications in complex matrices. Current challenges and future perspectives: a critical review
VL  - 148
IS  - 14
SP  - 3130
EP  - 3152
DO  - 10.1039/D3AN00498H
ER  - 

@article{
author = "Ražić, Slavica and Arsenijević, Jelena and Đogo Mračević, Svetlana and Mušović, Jasmina and Trtić-Petrović, Tatjana",
year = "2023",
abstract = "More environment-friendly solvents in analytical chemistry are almost inevitable in both sample preparation and analysis to meet the high standards of sustainable chemistry and human welfare. In this review paper, a critical look at the advantages and still unsolved problems of most potential classes of green solvents is presented to give an overview of the current state-of-the-art in this field. Replacing volatile organic compounds (VOCs) by ecofriendly and benign solvents in extractions/separations in sample preparation, as the most tedious and demanding step in analysis, is one of roads toward sustainable chemistry. Water under sub- and supercritical conditions, carbon-dioxide, ionic liquids (ILs), deep eutectic solvents (DESs), and those of natural origin (NADES) belong to the most promising classes of solvents in green analytical chemistry. Basic theory and mechanisms of their use illustrated by representative but not exhaustive list of examples related to complex matrices (environmental and natural food products) from analytical practice are presented in this review. Perspectives of QuEChERS, in line with GAC principles, are highlighted, in line with current trends of “going green” for quick, easy, cheap, effective, rugged, and safe analytical methods. Compliance with green chemistry (GC), especially green analytical chemistry (GAC) principles, is not a fashionable issue but, more the trend toward a sustainable future with greener chemistry; thus, green metrics are an unavoidable tool to measure how green the applied method or procedure is. Herein, the most common tools will be presented and discussed, such as national environmental method index (NEMI), analytical ecoscale, green analytical procedure index (GAPI), analytical greenness calculator (AGREE), complementary green analytical procedure index (ComplexGAPI), and analytical greenness metric for sample preparation (AGREEprep). The future trends for research and development in this still expanding field are presented in a critical view of advantages and disadvantages as well as improvement of the validation of analytical procedures. The creation of new certified reference materials (CRMs) and validated methods for specified analytes in complex matrices is a demanding task in the coming years. Tailor-made solvents with physicochemical properties for intended use are required for the selective extraction and separation and open numerous possibilities and huge potential for future research and industrial applications.",
journal = "Analyst",
title = "Greener chemistry in analytical sciences: from green solvents to applications in complex matrices. Current challenges and future perspectives: a critical review",
volume = "148",
number = "14",
pages = "3130-3152",
doi = "10.1039/D3AN00498H"
}

Ražić, S., Arsenijević, J., Đogo Mračević, S., Mušović, J.,& Trtić-Petrović, T.. (2023). Greener chemistry in analytical sciences: from green solvents to applications in complex matrices. Current challenges and future perspectives: a critical review. in Analyst, 148(14), 3130-3152.
https://doi.org/10.1039/D3AN00498H

Ražić S, Arsenijević J, Đogo Mračević S, Mušović J, Trtić-Petrović T. Greener chemistry in analytical sciences: from green solvents to applications in complex matrices. Current challenges and future perspectives: a critical review. in Analyst. 2023;148(14):3130-3152.
doi:10.1039/D3AN00498H .

Ražić, Slavica, Arsenijević, Jelena, Đogo Mračević, Svetlana, Mušović, Jasmina, Trtić-Petrović, Tatjana, "Greener chemistry in analytical sciences: from green solvents to applications in complex matrices. Current challenges and future perspectives: a critical review" in Analyst, 148, no. 14 (2023):3130-3152,
https://doi.org/10.1039/D3AN00498H . .

TY  - JOUR
AU  - Ražić, Slavica
AU  - Gadžurić, Slobodan
AU  - Trtić-Petrović, Tatjana
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12045
AB  - The widespread use of ionic liquids (ILs) as greener solvents in analytical sciences, especially in sample pretreatment, has focused attention on exploiting their enormous potential, not only on eliminating and improving the drawbacks faced by scientists. These ionic compounds with unique physicochemical properties can be tuned through smart synthesis, combining cations and anions, so that the compound exhibits excellent properties for its intended purpose. Ionic liquids are rightly referred to as designer solvents. Validation of a newly proposed analytical methods using ionic liquids, either in sample preparation or in further analysis, is a critical process to demonstrate that a particular analytical method is fit for purpose and provides reliable and accurate results. In addition, this article specially addressed the potential toxicity of ionic liquids with the modest goal of assisting researchers in this field by expanding their target areas.
T2  - Analytical and Bioanalytical Chemistry
T1  - Ionic liquids in green analytical chemistry—are they that good and green enough?
DO  - 10.1007/s00216-023-05045-3
ER  - 

@article{
author = "Ražić, Slavica and Gadžurić, Slobodan and Trtić-Petrović, Tatjana",
year = "2023",
abstract = "The widespread use of ionic liquids (ILs) as greener solvents in analytical sciences, especially in sample pretreatment, has focused attention on exploiting their enormous potential, not only on eliminating and improving the drawbacks faced by scientists. These ionic compounds with unique physicochemical properties can be tuned through smart synthesis, combining cations and anions, so that the compound exhibits excellent properties for its intended purpose. Ionic liquids are rightly referred to as designer solvents. Validation of a newly proposed analytical methods using ionic liquids, either in sample preparation or in further analysis, is a critical process to demonstrate that a particular analytical method is fit for purpose and provides reliable and accurate results. In addition, this article specially addressed the potential toxicity of ionic liquids with the modest goal of assisting researchers in this field by expanding their target areas.",
journal = "Analytical and Bioanalytical Chemistry",
title = "Ionic liquids in green analytical chemistry—are they that good and green enough?",
doi = "10.1007/s00216-023-05045-3"
}

Ražić, S., Gadžurić, S.,& Trtić-Petrović, T.. (2023). Ionic liquids in green analytical chemistry—are they that good and green enough?. in Analytical and Bioanalytical Chemistry.
https://doi.org/10.1007/s00216-023-05045-3

Ražić S, Gadžurić S, Trtić-Petrović T. Ionic liquids in green analytical chemistry—are they that good and green enough?. in Analytical and Bioanalytical Chemistry. 2023;.
doi:10.1007/s00216-023-05045-3 .

Ražić, Slavica, Gadžurić, Slobodan, Trtić-Petrović, Tatjana, "Ionic liquids in green analytical chemistry—are they that good and green enough?" in Analytical and Bioanalytical Chemistry (2023),
https://doi.org/10.1007/s00216-023-05045-3 . .

TY  - JOUR
AU  - Mušović, Jasmina
AU  - Vraneš, Milan
AU  - Papović, Snežana
AU  - Gadžurić, Slobodan
AU  - Ražić, Slavica
AU  - Trtić-Petrović, Tatjana M.
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10596
AB  - Although sample preparation, as an unavoidable step of the analytical process should be simple, it is very often identified as a bottleneck. Simplicity of sample preparation based on cost-effective and non-hazardous materials is mandatory for any sustainable and environmental friendly approach. Aqueous biphasic systems (ABS), based on functionalized ionic liquids (FILs) are acceptable alternatives to classical extraction procedures, due to the replacement of organic solvent with diluted aqueous-soluble ionic liquids. In this work, two water soluble FILs based on 2-mercaptobenzothiazolate anion, [mbt]: 1-butyl-3-methylimidazolium [mbt] ([bmim][mbt]) and 1-ethyl-3-methylimidazolium [mbt] ([emim][mbt]), were designed and synthesized in order to selectively extract Cd(II) and Pb(II) from the river sediment. It was found that [mbt]– anion acts as the ligand and forms complexes with Cd(II) and Pb(II) which are responsible for their efficient extraction, while cation is more responsible for the formation of ABS. Partition coefficients of 408 and 180 for Cd(II) and Pb(II), respectively, were obtained using ABS based on [bmim][mbt]. Direct extraction of Cd(II) and Pb(II) from the river sediment has been investigated and obtained optimal conditions are: 60 min direct contact of the aqueous solution of [bmim][mbt] and the sediment sample at 90 °C, followed by formation of ABS upon addition of potassium citrate. Using AGRE and AGREEprep tools greenness of the proposed method for direct extraction of Cd(II) and Pb(II) from the sediment are calculated. Obtained values of 0.69 and 0.71 for Cd(II) and Pb(II) extraction, respectively, showed a high level of the greenness of the proposed method.
T2  - Journal of Molecular Liquids
T1  - Greener sample preparation method for direct determination of Cd(II) and Pb(II) in river sediment based on an aqueous biphasic system with functionalized ionic liquids
VL  - 369
SP  - 120974
DO  - 10.1016/j.molliq.2022.120974
ER  - 

@article{
author = "Mušović, Jasmina and Vraneš, Milan and Papović, Snežana and Gadžurić, Slobodan and Ražić, Slavica and Trtić-Petrović, Tatjana M.",
year = "2023",
abstract = "Although sample preparation, as an unavoidable step of the analytical process should be simple, it is very often identified as a bottleneck. Simplicity of sample preparation based on cost-effective and non-hazardous materials is mandatory for any sustainable and environmental friendly approach. Aqueous biphasic systems (ABS), based on functionalized ionic liquids (FILs) are acceptable alternatives to classical extraction procedures, due to the replacement of organic solvent with diluted aqueous-soluble ionic liquids. In this work, two water soluble FILs based on 2-mercaptobenzothiazolate anion, [mbt]: 1-butyl-3-methylimidazolium [mbt] ([bmim][mbt]) and 1-ethyl-3-methylimidazolium [mbt] ([emim][mbt]), were designed and synthesized in order to selectively extract Cd(II) and Pb(II) from the river sediment. It was found that [mbt]– anion acts as the ligand and forms complexes with Cd(II) and Pb(II) which are responsible for their efficient extraction, while cation is more responsible for the formation of ABS. Partition coefficients of 408 and 180 for Cd(II) and Pb(II), respectively, were obtained using ABS based on [bmim][mbt]. Direct extraction of Cd(II) and Pb(II) from the river sediment has been investigated and obtained optimal conditions are: 60 min direct contact of the aqueous solution of [bmim][mbt] and the sediment sample at 90 °C, followed by formation of ABS upon addition of potassium citrate. Using AGRE and AGREEprep tools greenness of the proposed method for direct extraction of Cd(II) and Pb(II) from the sediment are calculated. Obtained values of 0.69 and 0.71 for Cd(II) and Pb(II) extraction, respectively, showed a high level of the greenness of the proposed method.",
journal = "Journal of Molecular Liquids",
title = "Greener sample preparation method for direct determination of Cd(II) and Pb(II) in river sediment based on an aqueous biphasic system with functionalized ionic liquids",
volume = "369",
pages = "120974",
doi = "10.1016/j.molliq.2022.120974"
}

Mušović, J., Vraneš, M., Papović, S., Gadžurić, S., Ražić, S.,& Trtić-Petrović, T. M.. (2023). Greener sample preparation method for direct determination of Cd(II) and Pb(II) in river sediment based on an aqueous biphasic system with functionalized ionic liquids. in Journal of Molecular Liquids, 369, 120974.
https://doi.org/10.1016/j.molliq.2022.120974

Mušović J, Vraneš M, Papović S, Gadžurić S, Ražić S, Trtić-Petrović TM. Greener sample preparation method for direct determination of Cd(II) and Pb(II) in river sediment based on an aqueous biphasic system with functionalized ionic liquids. in Journal of Molecular Liquids. 2023;369:120974.
doi:10.1016/j.molliq.2022.120974 .

Mušović, Jasmina, Vraneš, Milan, Papović, Snežana, Gadžurić, Slobodan, Ražić, Slavica, Trtić-Petrović, Tatjana M., "Greener sample preparation method for direct determination of Cd(II) and Pb(II) in river sediment based on an aqueous biphasic system with functionalized ionic liquids" in Journal of Molecular Liquids, 369 (2023):120974,
https://doi.org/10.1016/j.molliq.2022.120974 . .

TY  - JOUR
AU  - Culicov, Otilia Ana
AU  - Trtić-Petrović, Tatjana M.
AU  - Balvanović, Roman V.
AU  - Petković, Anđelka
AU  - Ražić, Slavica
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9654
AB  - Recent studies show that lanthanides (Ln) are becoming emerging pollutants due to their wide application in new technologies, but their environmental fate, transport, and possible accumulation are still relatively unknown. This study aims to determine major and trace elements including Ln in the Danube River sediment which either belong or close to the Iron Gate Reservoir. The Iron Gate Reservoir is characterized by accumulation of sediments as an effect of building hydropower dam Iron Gate I. The surface sediments were collected on the Danube River—1141 to 864 km and three tributaries along this waterway. Two samples of deep sediments were used for comparison. The results indicate the significant upward enrichment of Zn, Sb, Cr, Nd, and Dy in sediments belongs to the Iron Gate Reservoir. The sample 4-Smed is labelled as a hot spot of contamination with Zn, Cr, As, Sb, Nd, and Dy. Also, a trend of increasing concentration in the time period from 1995 to 2016 was found for elements Zn, Cr, and Ni in sediment samples in the Iron Gate Reservoir. Chemometric analysis shows the grouping of sample sites into clusters characterized by the following properties: (i) increased concentration of all measured elements (samples within the Iron Gate Reservoir); (ii) increased Cu concentration (11-Pek); and (iii) lower concentrations of the measured elements (deep sediments). The data presented hereby contribute to the monitoring of pollution of the River Danube sediments and give the first view of Ln profile in the studied sediments.
T2  - Environmental Science and Pollution Research
T1  - Spatial distribution of multielements including lanthanides in sediments of Iron Gate I Reservoir in the Danube River
VL  - 28
IS  - 33
SP  - 44877
EP  - 44889
DO  - 10.1007/s11356-021-13752-6
ER  - 

@article{
author = "Culicov, Otilia Ana and Trtić-Petrović, Tatjana M. and Balvanović, Roman V. and Petković, Anđelka and Ražić, Slavica",
year = "2021",
abstract = "Recent studies show that lanthanides (Ln) are becoming emerging pollutants due to their wide application in new technologies, but their environmental fate, transport, and possible accumulation are still relatively unknown. This study aims to determine major and trace elements including Ln in the Danube River sediment which either belong or close to the Iron Gate Reservoir. The Iron Gate Reservoir is characterized by accumulation of sediments as an effect of building hydropower dam Iron Gate I. The surface sediments were collected on the Danube River—1141 to 864 km and three tributaries along this waterway. Two samples of deep sediments were used for comparison. The results indicate the significant upward enrichment of Zn, Sb, Cr, Nd, and Dy in sediments belongs to the Iron Gate Reservoir. The sample 4-Smed is labelled as a hot spot of contamination with Zn, Cr, As, Sb, Nd, and Dy. Also, a trend of increasing concentration in the time period from 1995 to 2016 was found for elements Zn, Cr, and Ni in sediment samples in the Iron Gate Reservoir. Chemometric analysis shows the grouping of sample sites into clusters characterized by the following properties: (i) increased concentration of all measured elements (samples within the Iron Gate Reservoir); (ii) increased Cu concentration (11-Pek); and (iii) lower concentrations of the measured elements (deep sediments). The data presented hereby contribute to the monitoring of pollution of the River Danube sediments and give the first view of Ln profile in the studied sediments.",
journal = "Environmental Science and Pollution Research",
title = "Spatial distribution of multielements including lanthanides in sediments of Iron Gate I Reservoir in the Danube River",
volume = "28",
number = "33",
pages = "44877-44889",
doi = "10.1007/s11356-021-13752-6"
}

Culicov, O. A., Trtić-Petrović, T. M., Balvanović, R. V., Petković, A.,& Ražić, S.. (2021). Spatial distribution of multielements including lanthanides in sediments of Iron Gate I Reservoir in the Danube River. in Environmental Science and Pollution Research, 28(33), 44877-44889.
https://doi.org/10.1007/s11356-021-13752-6

Culicov OA, Trtić-Petrović TM, Balvanović RV, Petković A, Ražić S. Spatial distribution of multielements including lanthanides in sediments of Iron Gate I Reservoir in the Danube River. in Environmental Science and Pollution Research. 2021;28(33):44877-44889.
doi:10.1007/s11356-021-13752-6 .

Culicov, Otilia Ana, Trtić-Petrović, Tatjana M., Balvanović, Roman V., Petković, Anđelka, Ražić, Slavica, "Spatial distribution of multielements including lanthanides in sediments of Iron Gate I Reservoir in the Danube River" in Environmental Science and Pollution Research, 28, no. 33 (2021):44877-44889,
https://doi.org/10.1007/s11356-021-13752-6 . .

TY  - JOUR
AU  - Radosavljević-Stevanović, Nataša
AU  - Marković, Jelena P.
AU  - Agatonović-Kustrin, Snežana
AU  - Ražić, Slavica
PY  - 2014
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/5945
AB  - Illicit production and trade of Cannabis sativa affect many societies. This drug is the most popular and easy to produce. Important information for the authorities is the production locality and the indicators of a particular production. This work is an attempt to recognise correlations between the metal content in the different parts of C. sativa L., in soils where plants were cultivated and the cannabinoids content, as a potential indicator. The organic fraction of the leaves of Cannabis plants was investigated by GC-FID analysis. In addition, the determination of Cu, Fe, Cr, Mn, Zn, Ca and Mg was realised by spectroscopic techniques (FAAS and GFAAS). In this study, numerous correlations between metal content in plants and soil, already confirmed in previous publications, were analysed applying chemometric unsupervised methods, that is, principal component analysis, factor analysis and cluster analysis, in order to highlight their role in the biosynthesis of cannabinoids.
T2  - Natural Product Research
T1  - Metals and organic compounds in the biosynthesis of cannabinoids: a chemometric approach to the analysis of Cannabis sativa samples
VL  - 28
IS  - 8
SP  - 511
EP  - 516
DO  - 10.1080/14786419.2014.880912
ER  - 

@article{
author = "Radosavljević-Stevanović, Nataša and Marković, Jelena P. and Agatonović-Kustrin, Snežana and Ražić, Slavica",
year = "2014",
abstract = "Illicit production and trade of Cannabis sativa affect many societies. This drug is the most popular and easy to produce. Important information for the authorities is the production locality and the indicators of a particular production. This work is an attempt to recognise correlations between the metal content in the different parts of C. sativa L., in soils where plants were cultivated and the cannabinoids content, as a potential indicator. The organic fraction of the leaves of Cannabis plants was investigated by GC-FID analysis. In addition, the determination of Cu, Fe, Cr, Mn, Zn, Ca and Mg was realised by spectroscopic techniques (FAAS and GFAAS). In this study, numerous correlations between metal content in plants and soil, already confirmed in previous publications, were analysed applying chemometric unsupervised methods, that is, principal component analysis, factor analysis and cluster analysis, in order to highlight their role in the biosynthesis of cannabinoids.",
journal = "Natural Product Research",
title = "Metals and organic compounds in the biosynthesis of cannabinoids: a chemometric approach to the analysis of Cannabis sativa samples",
volume = "28",
number = "8",
pages = "511-516",
doi = "10.1080/14786419.2014.880912"
}

Radosavljević-Stevanović, N., Marković, J. P., Agatonović-Kustrin, S.,& Ražić, S.. (2014). Metals and organic compounds in the biosynthesis of cannabinoids: a chemometric approach to the analysis of Cannabis sativa samples. in Natural Product Research, 28(8), 511-516.
https://doi.org/10.1080/14786419.2014.880912

Radosavljević-Stevanović N, Marković JP, Agatonović-Kustrin S, Ražić S. Metals and organic compounds in the biosynthesis of cannabinoids: a chemometric approach to the analysis of Cannabis sativa samples. in Natural Product Research. 2014;28(8):511-516.
doi:10.1080/14786419.2014.880912 .

Radosavljević-Stevanović, Nataša, Marković, Jelena P., Agatonović-Kustrin, Snežana, Ražić, Slavica, "Metals and organic compounds in the biosynthesis of cannabinoids: a chemometric approach to the analysis of Cannabis sativa samples" in Natural Product Research, 28, no. 8 (2014):511-516,
https://doi.org/10.1080/14786419.2014.880912 . .

TY  - JOUR
AU  - Arsenijević, Jelena
AU  - Marković, Jelena P.
AU  - Sostaric, Ivan
AU  - Ražić, Slavica
PY  - 2013
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/5723
AB  - The volatile fraction of the leaves of Thymus pannonicus All. (Lamiaceae) was analyzed by headspace extraction followed by GC-FID and GC-MS analysis. The different headspace profiles were recognized, with citral and with monoterpene hydrocarbons as dominant compounds. In addition, the determination of Cr, Co, Ni, Mo, Cu, Zn, Mn, Fe, Mg, Ca, K and Na was conducted by spectroscopic techniques (FAAS, GFAAS and ICP-OES). In order to evaluate the relationship between volatile organic compounds and metals, a chemometrics approach was applied. The data obtained by analysis of the headspace and elemental content were subjected to correlation analysis, factor analysis, principal component analysis and cluster analysis. A number of significant correlations of metals with plant volatiles were found. Correlation of Zn with citral, Mn with oxygenated monoterpenes and Mg with beta-bourbonene, could be explained by involvement of metals in the biosynthesis of volatile organic compounds. (C) 2013 Elsevier Masson SAS. All rights reserved.
T2  - Plant Physiology and Biochemistry
T1  - A chemometrics as a powerful tool in the elucidation of the role of metals in the biosynthesis of volatile organic compounds in Hungarian thyme samples
VL  - 71
SP  - 298
EP  - 306
DO  - 10.1016/j.plaphy.2013.08.002
ER  - 

@article{
author = "Arsenijević, Jelena and Marković, Jelena P. and Sostaric, Ivan and Ražić, Slavica",
year = "2013",
abstract = "The volatile fraction of the leaves of Thymus pannonicus All. (Lamiaceae) was analyzed by headspace extraction followed by GC-FID and GC-MS analysis. The different headspace profiles were recognized, with citral and with monoterpene hydrocarbons as dominant compounds. In addition, the determination of Cr, Co, Ni, Mo, Cu, Zn, Mn, Fe, Mg, Ca, K and Na was conducted by spectroscopic techniques (FAAS, GFAAS and ICP-OES). In order to evaluate the relationship between volatile organic compounds and metals, a chemometrics approach was applied. The data obtained by analysis of the headspace and elemental content were subjected to correlation analysis, factor analysis, principal component analysis and cluster analysis. A number of significant correlations of metals with plant volatiles were found. Correlation of Zn with citral, Mn with oxygenated monoterpenes and Mg with beta-bourbonene, could be explained by involvement of metals in the biosynthesis of volatile organic compounds. (C) 2013 Elsevier Masson SAS. All rights reserved.",
journal = "Plant Physiology and Biochemistry",
title = "A chemometrics as a powerful tool in the elucidation of the role of metals in the biosynthesis of volatile organic compounds in Hungarian thyme samples",
volume = "71",
pages = "298-306",
doi = "10.1016/j.plaphy.2013.08.002"
}

Arsenijević, J., Marković, J. P., Sostaric, I.,& Ražić, S.. (2013). A chemometrics as a powerful tool in the elucidation of the role of metals in the biosynthesis of volatile organic compounds in Hungarian thyme samples. in Plant Physiology and Biochemistry, 71, 298-306.
https://doi.org/10.1016/j.plaphy.2013.08.002

Arsenijević J, Marković JP, Sostaric I, Ražić S. A chemometrics as a powerful tool in the elucidation of the role of metals in the biosynthesis of volatile organic compounds in Hungarian thyme samples. in Plant Physiology and Biochemistry. 2013;71:298-306.
doi:10.1016/j.plaphy.2013.08.002 .

Arsenijević, Jelena, Marković, Jelena P., Sostaric, Ivan, Ražić, Slavica, "A chemometrics as a powerful tool in the elucidation of the role of metals in the biosynthesis of volatile organic compounds in Hungarian thyme samples" in Plant Physiology and Biochemistry, 71 (2013):298-306,
https://doi.org/10.1016/j.plaphy.2013.08.002 . .

TY  - JOUR
AU  - Đogo, Svetlana
AU  - Ražić, Slavica
AU  - Manojlović, Dragan D.
AU  - Slavković, Latinka J.
PY  - 2011
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/4217
AB  - Mentha piperita L. (Lamiaceae) was cultivated under the controlled laboratory conditions in the presence of varying levels of trivalent and hexavalent chromium in order to determine its capacity to control chromium uptake and its tolerance limit. The plants were grown in pots at 25 degrees C with controlled soil moisture (about 80 % of the water retention capacity). The soil was treated with increasing concentrations of Cr(NO3)3 (40, 80, 120, and 200 mg kg(-1)) and K2Cr2O7 (2.5, 5, 10, and 15 mg kg(-1)). A control group of plants was grown without the addition of chromium to the soil. For each concentration, three acidity levels were tested: natural, one pH unit below and one above the natural acidity of the soil (pH(2) 6, pH(1) 5 and pH(3) 7). The plant samples were digested according to the standard procedure and chromium content was determined by GFAAS. For all plants, the transportation index was calculated and the results (expressed in mg kg(-1)) at pH(1), pH(2) and pH(3), respectively, were: 0.21-0.80, 0.06-1.06 and 0.04-0.52. The recoveries were good (72.73-115.3 %) as evidenced by the analysis of certified reference materials (NIST SRM 8433 - Corn Bran and NIST SRM 1547 - Peach Leaves). The mobility of chromium through the plants tissues is discussed in regard to its competition with iron and manganese for transport binding sites; hence Mn and Fe were also determined.
T2  - Journal of the Serbian Chemical Society
T1  - Analysis of the bioavailability of Cr(III) and Cr(VI) based on the determination of chromium in Mentha piperita by graphite furnace atomic absorption spectrometry
VL  - 76
IS  - 1
SP  - 143
EP  - 153
DO  - 10.2298/JSC100401130D
ER  - 

@article{
author = "Đogo, Svetlana and Ražić, Slavica and Manojlović, Dragan D. and Slavković, Latinka J.",
year = "2011",
abstract = "Mentha piperita L. (Lamiaceae) was cultivated under the controlled laboratory conditions in the presence of varying levels of trivalent and hexavalent chromium in order to determine its capacity to control chromium uptake and its tolerance limit. The plants were grown in pots at 25 degrees C with controlled soil moisture (about 80 % of the water retention capacity). The soil was treated with increasing concentrations of Cr(NO3)3 (40, 80, 120, and 200 mg kg(-1)) and K2Cr2O7 (2.5, 5, 10, and 15 mg kg(-1)). A control group of plants was grown without the addition of chromium to the soil. For each concentration, three acidity levels were tested: natural, one pH unit below and one above the natural acidity of the soil (pH(2) 6, pH(1) 5 and pH(3) 7). The plant samples were digested according to the standard procedure and chromium content was determined by GFAAS. For all plants, the transportation index was calculated and the results (expressed in mg kg(-1)) at pH(1), pH(2) and pH(3), respectively, were: 0.21-0.80, 0.06-1.06 and 0.04-0.52. The recoveries were good (72.73-115.3 %) as evidenced by the analysis of certified reference materials (NIST SRM 8433 - Corn Bran and NIST SRM 1547 - Peach Leaves). The mobility of chromium through the plants tissues is discussed in regard to its competition with iron and manganese for transport binding sites; hence Mn and Fe were also determined.",
journal = "Journal of the Serbian Chemical Society",
title = "Analysis of the bioavailability of Cr(III) and Cr(VI) based on the determination of chromium in Mentha piperita by graphite furnace atomic absorption spectrometry",
volume = "76",
number = "1",
pages = "143-153",
doi = "10.2298/JSC100401130D"
}

Đogo, S., Ražić, S., Manojlović, D. D.,& Slavković, L. J.. (2011). Analysis of the bioavailability of Cr(III) and Cr(VI) based on the determination of chromium in Mentha piperita by graphite furnace atomic absorption spectrometry. in Journal of the Serbian Chemical Society, 76(1), 143-153.
https://doi.org/10.2298/JSC100401130D

Đogo S, Ražić S, Manojlović DD, Slavković LJ. Analysis of the bioavailability of Cr(III) and Cr(VI) based on the determination of chromium in Mentha piperita by graphite furnace atomic absorption spectrometry. in Journal of the Serbian Chemical Society. 2011;76(1):143-153.
doi:10.2298/JSC100401130D .

Đogo, Svetlana, Ražić, Slavica, Manojlović, Dragan D., Slavković, Latinka J., "Analysis of the bioavailability of Cr(III) and Cr(VI) based on the determination of chromium in Mentha piperita by graphite furnace atomic absorption spectrometry" in Journal of the Serbian Chemical Society, 76, no. 1 (2011):143-153,
https://doi.org/10.2298/JSC100401130D . .

TY  - JOUR
AU  - Ražić, Slavica
AU  - Onjia, Antonije E.
PY  - 2010
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/4176
AB  - Chemical analysis in conjunction with multivariate data evaluation methods was used to study elemental profiles and geographical origin of wines from central Balkan countries (Serbia Montenegro and Macedonia) Nine elements (Na K Mg Ca Fe Mn Zn Cu and Pb) chosen as chemical descriptors were analyzed in 41 commercial wine samples Unsupervised pattern recognition methods principal component analysis (PCA) and factor analysis identified the main factors controlling the data variability while the application of hierarchical cluster analysis (HCA) highlighted a differentiation between sample groups belonging to different variable inputs Three PCs were shown to be the most significant together accounting for 70 8% of the total variance Supervised pattern recognition methods linear discriminant analysis (LDA) k nearest neighbor (kNN) soft independent modeling of class analogy (SIMCA) and artificial neural network (ANN) applied to the classification of wine samples demonstrated different recognition and prediction abilities The recognition rate for LDA was 97 6% and the percentage of classification obtained by kNN SIMCA and ANN was 100% However the LDA method produced the best prediction rate of 83 3% whereas kNN SIMCA and ANN gave much lower percentages of correctly classified samples at 72 2 61 1 and 55 6% respectively Trace elements seem to be suitable descriptors for wine samples studied by classification methods since their concentrations comprising both natural and other sources of influence are attributed to grapegrowing and winemaking sites Comparison of pattern recognition methods reveals the difference in their classification power
T2  - American Journal of Enology and Viticulture
T1  - Trace Element Analysis and Pattern Recognition Techniques in Classification of Wine from Central Balkan Countries
VL  - 61
IS  - 4
SP  - 506
EP  - 511
DO  - 10.5344/ajev.2010.10002
ER  - 

@article{
author = "Ražić, Slavica and Onjia, Antonije E.",
year = "2010",
abstract = "Chemical analysis in conjunction with multivariate data evaluation methods was used to study elemental profiles and geographical origin of wines from central Balkan countries (Serbia Montenegro and Macedonia) Nine elements (Na K Mg Ca Fe Mn Zn Cu and Pb) chosen as chemical descriptors were analyzed in 41 commercial wine samples Unsupervised pattern recognition methods principal component analysis (PCA) and factor analysis identified the main factors controlling the data variability while the application of hierarchical cluster analysis (HCA) highlighted a differentiation between sample groups belonging to different variable inputs Three PCs were shown to be the most significant together accounting for 70 8% of the total variance Supervised pattern recognition methods linear discriminant analysis (LDA) k nearest neighbor (kNN) soft independent modeling of class analogy (SIMCA) and artificial neural network (ANN) applied to the classification of wine samples demonstrated different recognition and prediction abilities The recognition rate for LDA was 97 6% and the percentage of classification obtained by kNN SIMCA and ANN was 100% However the LDA method produced the best prediction rate of 83 3% whereas kNN SIMCA and ANN gave much lower percentages of correctly classified samples at 72 2 61 1 and 55 6% respectively Trace elements seem to be suitable descriptors for wine samples studied by classification methods since their concentrations comprising both natural and other sources of influence are attributed to grapegrowing and winemaking sites Comparison of pattern recognition methods reveals the difference in their classification power",
journal = "American Journal of Enology and Viticulture",
title = "Trace Element Analysis and Pattern Recognition Techniques in Classification of Wine from Central Balkan Countries",
volume = "61",
number = "4",
pages = "506-511",
doi = "10.5344/ajev.2010.10002"
}

Ražić, S.,& Onjia, A. E.. (2010). Trace Element Analysis and Pattern Recognition Techniques in Classification of Wine from Central Balkan Countries. in American Journal of Enology and Viticulture, 61(4), 506-511.
https://doi.org/10.5344/ajev.2010.10002

Ražić S, Onjia AE. Trace Element Analysis and Pattern Recognition Techniques in Classification of Wine from Central Balkan Countries. in American Journal of Enology and Viticulture. 2010;61(4):506-511.
doi:10.5344/ajev.2010.10002 .

Ražić, Slavica, Onjia, Antonije E., "Trace Element Analysis and Pattern Recognition Techniques in Classification of Wine from Central Balkan Countries" in American Journal of Enology and Viticulture, 61, no. 4 (2010):506-511,
https://doi.org/10.5344/ajev.2010.10002 . .

TY  - JOUR
AU  - Ražić, Slavica
AU  - Đogo, Svetlana
AU  - Slavković, Latinka J.
PY  - 2008
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3461
AB  - Trace and major elements were determined in medicinal herbs (Cynara scolymus, Matricaria chamomilla, Artemisia absinthium L., Achillea millefolium, and Inula britannica) as well as in rhizosphere soil samples. Based on the results obtained after microwave-acid-assisted digestion (nitric acid + hydrogen peroxide) and single-step extraction (ammonium acetate), the real and potential acidity and redox potential of the soils, uptake, mobility, and bioavailability of potassium, calcium, magnesium, iron, manganese, copper, zinc, nickel, chromium, lead, and cadmium are discussed. By calculating the bioconcentration factors and their deviation from the recommended values, elevated concentrations, were explained in terms of contamination and pollution. The concentrations measured in both plants and soil samples were below maximum allowable concentration ranges considered for the European Union.
T2  - Journal of Natural Medicines
T1  - Investigation on bioavailability of some essential and toxic elements in medicinal herbs
VL  - 62
IS  - 3
SP  - 340
EP  - 344
DO  - 10.1007/s11418-008-0240-5
ER  - 

@article{
author = "Ražić, Slavica and Đogo, Svetlana and Slavković, Latinka J.",
year = "2008",
abstract = "Trace and major elements were determined in medicinal herbs (Cynara scolymus, Matricaria chamomilla, Artemisia absinthium L., Achillea millefolium, and Inula britannica) as well as in rhizosphere soil samples. Based on the results obtained after microwave-acid-assisted digestion (nitric acid + hydrogen peroxide) and single-step extraction (ammonium acetate), the real and potential acidity and redox potential of the soils, uptake, mobility, and bioavailability of potassium, calcium, magnesium, iron, manganese, copper, zinc, nickel, chromium, lead, and cadmium are discussed. By calculating the bioconcentration factors and their deviation from the recommended values, elevated concentrations, were explained in terms of contamination and pollution. The concentrations measured in both plants and soil samples were below maximum allowable concentration ranges considered for the European Union.",
journal = "Journal of Natural Medicines",
title = "Investigation on bioavailability of some essential and toxic elements in medicinal herbs",
volume = "62",
number = "3",
pages = "340-344",
doi = "10.1007/s11418-008-0240-5"
}

Ražić, S., Đogo, S.,& Slavković, L. J.. (2008). Investigation on bioavailability of some essential and toxic elements in medicinal herbs. in Journal of Natural Medicines, 62(3), 340-344.
https://doi.org/10.1007/s11418-008-0240-5

Ražić S, Đogo S, Slavković LJ. Investigation on bioavailability of some essential and toxic elements in medicinal herbs. in Journal of Natural Medicines. 2008;62(3):340-344.
doi:10.1007/s11418-008-0240-5 .

Ražić, Slavica, Đogo, Svetlana, Slavković, Latinka J., "Investigation on bioavailability of some essential and toxic elements in medicinal herbs" in Journal of Natural Medicines, 62, no. 3 (2008):340-344,
https://doi.org/10.1007/s11418-008-0240-5 . .

TY  - JOUR
AU  - Ražić, Slavica
AU  - Čokeša, Đuro
AU  - Sremac, Snežana
PY  - 2007
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3347
AB  - The contents of five metals (Cu, Mn, Fe, Cd, and Pb) in several red and white wines originating from different regions of Serbia were determined by name and graphite furnace atomic absorption spectrometry. The data were processed using chemometric techniques. Principal component and factor analysis were applied in order to highlight the relations between the elements and, after data reduction, three main factors controlling variability were identified. Application of hierarchical cluster analysis to the studied wines indicated differentiation of the samples belonging to different origins. No discrimination between red and white wines was found.
T2  - Journal of the Serbian Chemical Society
T1  - Multivariate data visualization methods based on elemental analysis of wines by atomic absorption spectrometry
VL  - 72
IS  - 12
SP  - 1487
EP  - 1492
DO  - 10.2298/JSC0712487R
ER  - 

@article{
author = "Ražić, Slavica and Čokeša, Đuro and Sremac, Snežana",
year = "2007",
abstract = "The contents of five metals (Cu, Mn, Fe, Cd, and Pb) in several red and white wines originating from different regions of Serbia were determined by name and graphite furnace atomic absorption spectrometry. The data were processed using chemometric techniques. Principal component and factor analysis were applied in order to highlight the relations between the elements and, after data reduction, three main factors controlling variability were identified. Application of hierarchical cluster analysis to the studied wines indicated differentiation of the samples belonging to different origins. No discrimination between red and white wines was found.",
journal = "Journal of the Serbian Chemical Society",
title = "Multivariate data visualization methods based on elemental analysis of wines by atomic absorption spectrometry",
volume = "72",
number = "12",
pages = "1487-1492",
doi = "10.2298/JSC0712487R"
}

Ražić, S., Čokeša, Đ.,& Sremac, S.. (2007). Multivariate data visualization methods based on elemental analysis of wines by atomic absorption spectrometry. in Journal of the Serbian Chemical Society, 72(12), 1487-1492.
https://doi.org/10.2298/JSC0712487R

Ražić S, Čokeša Đ, Sremac S. Multivariate data visualization methods based on elemental analysis of wines by atomic absorption spectrometry. in Journal of the Serbian Chemical Society. 2007;72(12):1487-1492.
doi:10.2298/JSC0712487R .

Ražić, Slavica, Čokeša, Đuro, Sremac, Snežana, "Multivariate data visualization methods based on elemental analysis of wines by atomic absorption spectrometry" in Journal of the Serbian Chemical Society, 72, no. 12 (2007):1487-1492,
https://doi.org/10.2298/JSC0712487R . .

TY  - JOUR
AU  - Ražić, Slavica
AU  - Đogo, Svetlana
AU  - Slavković, Latinka J.
PY  - 2006
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/6621
AB  - Seven herbal drugs and corresponding rhizosphere soil samples from the plantation near Belgrade were analyzed for mineral content. Eleven metals (Cu, Zn, Mn, Fe, Cr, Ni, Pb, Cd, Ca, K and Mg) were selected as chemical features/descriptors and analyzed by FAAS/FAES and ETAAS. In a chemometrics evaluation of investigated plants-soil system, univariate, as well as multivariate statistics methods were applied. Principal component analysis (PCA) allowed considerable reduction in a number of variables and the detection of structure in the relationships between metals that give complementary information about the relations and elemental patterns within plants-soil system. The power of chemometrics was also used in exploring the potential natural and/or anthropogenic sources responsible for metal content in both medicinal plants and soil samples. Hierarchical cluster analysis (HCA) was used to explore herbal drugs grouping according to corresponding soil samples as additional information to the output obtained by PCA. (c) 2006 Elsevier B.V. All rights reserved.
T2  - Microchemical Journal
T1  - Multivariate characterization of herbal drugs and rhizosphere soil samples according to their metallic content
VL  - 84
IS  - 1-2
SP  - 93
EP  - 101
DO  - 10.1016/j.microc.2006.05.008
ER  - 

@article{
author = "Ražić, Slavica and Đogo, Svetlana and Slavković, Latinka J.",
year = "2006",
abstract = "Seven herbal drugs and corresponding rhizosphere soil samples from the plantation near Belgrade were analyzed for mineral content. Eleven metals (Cu, Zn, Mn, Fe, Cr, Ni, Pb, Cd, Ca, K and Mg) were selected as chemical features/descriptors and analyzed by FAAS/FAES and ETAAS. In a chemometrics evaluation of investigated plants-soil system, univariate, as well as multivariate statistics methods were applied. Principal component analysis (PCA) allowed considerable reduction in a number of variables and the detection of structure in the relationships between metals that give complementary information about the relations and elemental patterns within plants-soil system. The power of chemometrics was also used in exploring the potential natural and/or anthropogenic sources responsible for metal content in both medicinal plants and soil samples. Hierarchical cluster analysis (HCA) was used to explore herbal drugs grouping according to corresponding soil samples as additional information to the output obtained by PCA. (c) 2006 Elsevier B.V. All rights reserved.",
journal = "Microchemical Journal",
title = "Multivariate characterization of herbal drugs and rhizosphere soil samples according to their metallic content",
volume = "84",
number = "1-2",
pages = "93-101",
doi = "10.1016/j.microc.2006.05.008"
}

Ražić, S., Đogo, S.,& Slavković, L. J.. (2006). Multivariate characterization of herbal drugs and rhizosphere soil samples according to their metallic content. in Microchemical Journal, 84(1-2), 93-101.
https://doi.org/10.1016/j.microc.2006.05.008

Ražić S, Đogo S, Slavković LJ. Multivariate characterization of herbal drugs and rhizosphere soil samples according to their metallic content. in Microchemical Journal. 2006;84(1-2):93-101.
doi:10.1016/j.microc.2006.05.008 .

Ražić, Slavica, Đogo, Svetlana, Slavković, Latinka J., "Multivariate characterization of herbal drugs and rhizosphere soil samples according to their metallic content" in Microchemical Journal, 84, no. 1-2 (2006):93-101,
https://doi.org/10.1016/j.microc.2006.05.008 . .

TY  - JOUR
AU  - Ražić, Slavica
AU  - Đogo, Svetlana
AU  - Slavković, Latinka J.
PY  - 2006
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3135
AB  - Eleven elements (Cu, Zn, Mn, Fe, K, Ca, Mg, Ni, Cd, Pb and Cr) in seven herbal drugs (Salviae folium, Menthae piperitae, folium, Melissae folium, Lavandulae flos, Basilici herba, Marubii herba and Origani herha) and in rhizosphere soil samples were determined. A microwave digestion procedure preceded the measurements by the flame and electrothermal atomic absorption spectroscopy techniques (FAAS, ETAAS). For potentially hazardous elements and their bioavailability, BCF values were also calculated and discussed in order to identify possible sources of specific elements.
T2  - Journal of the Serbian Chemical Society
T1  - Inorganic analysis of herbal drugs. Part II. Plant and soil analysis - diverse bioavailability and uptake of essential and toxic elements
VL  - 71
IS  - 10
SP  - 1095
EP  - 1105
DO  - 10.2298/JSC0610095R
ER  - 

@article{
author = "Ražić, Slavica and Đogo, Svetlana and Slavković, Latinka J.",
year = "2006",
abstract = "Eleven elements (Cu, Zn, Mn, Fe, K, Ca, Mg, Ni, Cd, Pb and Cr) in seven herbal drugs (Salviae folium, Menthae piperitae, folium, Melissae folium, Lavandulae flos, Basilici herba, Marubii herba and Origani herha) and in rhizosphere soil samples were determined. A microwave digestion procedure preceded the measurements by the flame and electrothermal atomic absorption spectroscopy techniques (FAAS, ETAAS). For potentially hazardous elements and their bioavailability, BCF values were also calculated and discussed in order to identify possible sources of specific elements.",
journal = "Journal of the Serbian Chemical Society",
title = "Inorganic analysis of herbal drugs. Part II. Plant and soil analysis - diverse bioavailability and uptake of essential and toxic elements",
volume = "71",
number = "10",
pages = "1095-1105",
doi = "10.2298/JSC0610095R"
}

Ražić, S., Đogo, S.,& Slavković, L. J.. (2006). Inorganic analysis of herbal drugs. Part II. Plant and soil analysis - diverse bioavailability and uptake of essential and toxic elements. in Journal of the Serbian Chemical Society, 71(10), 1095-1105.
https://doi.org/10.2298/JSC0610095R

Ražić S, Đogo S, Slavković LJ. Inorganic analysis of herbal drugs. Part II. Plant and soil analysis - diverse bioavailability and uptake of essential and toxic elements. in Journal of the Serbian Chemical Society. 2006;71(10):1095-1105.
doi:10.2298/JSC0610095R .

Ražić, Slavica, Đogo, Svetlana, Slavković, Latinka J., "Inorganic analysis of herbal drugs. Part II. Plant and soil analysis - diverse bioavailability and uptake of essential and toxic elements" in Journal of the Serbian Chemical Society, 71, no. 10 (2006):1095-1105,
https://doi.org/10.2298/JSC0610095R . .

TY  - JOUR
AU  - Ražić, Slavica
AU  - Onjia, Antonije E.
AU  - Đogo, Svetlana
AU  - Slavković, Latinka J.
AU  - Popović, Aleksandar R.
PY  - 2005
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/6515
AB  - The concentrations of Cu, Zn, Mn, Fe, K, Ca, Mg, Al, Ba and B in 26 herbal drugs of special importance in phytopharmacywere studied. Flame atomic absorption and emission spectrometry (FAAS, FAES), as well as inductively coupled plasma atomic emission spectrometry (ICP-AES), were applied in this work. The whole procedure, from sample preparation, via dissolution, to measurements, was validated by using CRM (NIST 1573a-tomato leaves), and the obtained recovery values are in the range from 91 to 102%. Drug samples originated from medicinal plants cultivated in Serbia contained Cu (4.47-14.08 mg kg(-1)), Zn (8.4-54.5 mg kg(-1)), Mn (9-155 mg kg(-1)), Fe (47-546 mg kg(-1)), K (0.20-6.24%), Ca (0.18-1.84%), Mg (0.13-1.09%), Al (16-416 mg kg(-1)), Ba (11.70-84.83 mg kg(-1)) and B (5.1-118.7 mg kg(-1)). In order to get a better insight into the elemental patterns, a common chemometric approach to data evaluation was used. Four significant factors identified by principal component analysis (PCA) were attributed partly to the significant influential sources and high mobility of some elements thus referring to potential anthropogenic contamination as well. (C) 2005 Elsevier B.V. All rights reserved.
T2  - Talanta
T1  - Determination of metal content in some herbal drugs - Empirical and chemometric approach
VL  - 67
IS  - 1
SP  - 233
EP  - 239
DO  - 10.1016/j.talanta.2005.03.023
ER  - 

@article{
author = "Ražić, Slavica and Onjia, Antonije E. and Đogo, Svetlana and Slavković, Latinka J. and Popović, Aleksandar R.",
year = "2005",
abstract = "The concentrations of Cu, Zn, Mn, Fe, K, Ca, Mg, Al, Ba and B in 26 herbal drugs of special importance in phytopharmacywere studied. Flame atomic absorption and emission spectrometry (FAAS, FAES), as well as inductively coupled plasma atomic emission spectrometry (ICP-AES), were applied in this work. The whole procedure, from sample preparation, via dissolution, to measurements, was validated by using CRM (NIST 1573a-tomato leaves), and the obtained recovery values are in the range from 91 to 102%. Drug samples originated from medicinal plants cultivated in Serbia contained Cu (4.47-14.08 mg kg(-1)), Zn (8.4-54.5 mg kg(-1)), Mn (9-155 mg kg(-1)), Fe (47-546 mg kg(-1)), K (0.20-6.24%), Ca (0.18-1.84%), Mg (0.13-1.09%), Al (16-416 mg kg(-1)), Ba (11.70-84.83 mg kg(-1)) and B (5.1-118.7 mg kg(-1)). In order to get a better insight into the elemental patterns, a common chemometric approach to data evaluation was used. Four significant factors identified by principal component analysis (PCA) were attributed partly to the significant influential sources and high mobility of some elements thus referring to potential anthropogenic contamination as well. (C) 2005 Elsevier B.V. All rights reserved.",
journal = "Talanta",
title = "Determination of metal content in some herbal drugs - Empirical and chemometric approach",
volume = "67",
number = "1",
pages = "233-239",
doi = "10.1016/j.talanta.2005.03.023"
}

Ražić, S., Onjia, A. E., Đogo, S., Slavković, L. J.,& Popović, A. R.. (2005). Determination of metal content in some herbal drugs - Empirical and chemometric approach. in Talanta, 67(1), 233-239.
https://doi.org/10.1016/j.talanta.2005.03.023

Ražić S, Onjia AE, Đogo S, Slavković LJ, Popović AR. Determination of metal content in some herbal drugs - Empirical and chemometric approach. in Talanta. 2005;67(1):233-239.
doi:10.1016/j.talanta.2005.03.023 .

Ražić, Slavica, Onjia, Antonije E., Đogo, Svetlana, Slavković, Latinka J., Popović, Aleksandar R., "Determination of metal content in some herbal drugs - Empirical and chemometric approach" in Talanta, 67, no. 1 (2005):233-239,
https://doi.org/10.1016/j.talanta.2005.03.023 . .

TY  - JOUR
AU  - Ražić, Slavica
AU  - Đogo, Svetlana
AU  - Slavković, Latinka J.
AU  - Popović, Aleksandar R.
PY  - 2005
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2961
AB  - Elemental profiles of the total analyte content of major, minor and trace elements (Cu, Zn, Mn, Fe, K, Ca, Mg, Al, Ba and 13) in 8 herbal drugs, originating from medicinal plants of the family Lamiacae, were determined. Flame atomic absorption/emission spectroscopy (FAAS/FAES), inductively coupled plasma atomic emission spectroscopy (ICP-AES) and energy dispersive X-ray fluorescence (EDXRF) were applied, and the advantages and limitations of these techniques are also discussed. The whole procedure, from sample preparation via dissolution to the actual measurements, was validated byusing CRM (NIST 1573a-Tomato leaves). The recovery values obtained were in the range 90.64 - 101.58%. A high degree of similarity in their elemental profiles was noticed from the results of qualitative analysis, while quantitative analysis shows significant diversity due to the variety of the influencing sources. The medicinal plants investigated in this work contained Cu (5.92 - 14.79 mg kg(-1)), Zn (15.0 - 43.0 mg kg(-1)), Mn (25 - 111 mg kg(-1)), Fe (74 - 546 mg kg(-1)), K (1.80 - 6.24 %), Ca (0.90 - 1.43 %), Mg (0. 17 - 0.67 %), Al (49 - 378 mg kg(-1)), Ba (15.53 - 69.84 mg kg(-1)) and B (34.7 - 56.5 mg kg(-1)).
T2  - Journal of the Serbian Chemical Society
T1  - Inorganic analysis of herbal drugs. Part I. Metal determination in herbal drugs originating from medicinal plants of the family Lamiacae
VL  - 70
IS  - 11
SP  - 1347
EP  - 1355
DO  - 10.2298/JSC0511347R
ER  - 

@article{
author = "Ražić, Slavica and Đogo, Svetlana and Slavković, Latinka J. and Popović, Aleksandar R.",
year = "2005",
abstract = "Elemental profiles of the total analyte content of major, minor and trace elements (Cu, Zn, Mn, Fe, K, Ca, Mg, Al, Ba and 13) in 8 herbal drugs, originating from medicinal plants of the family Lamiacae, were determined. Flame atomic absorption/emission spectroscopy (FAAS/FAES), inductively coupled plasma atomic emission spectroscopy (ICP-AES) and energy dispersive X-ray fluorescence (EDXRF) were applied, and the advantages and limitations of these techniques are also discussed. The whole procedure, from sample preparation via dissolution to the actual measurements, was validated byusing CRM (NIST 1573a-Tomato leaves). The recovery values obtained were in the range 90.64 - 101.58%. A high degree of similarity in their elemental profiles was noticed from the results of qualitative analysis, while quantitative analysis shows significant diversity due to the variety of the influencing sources. The medicinal plants investigated in this work contained Cu (5.92 - 14.79 mg kg(-1)), Zn (15.0 - 43.0 mg kg(-1)), Mn (25 - 111 mg kg(-1)), Fe (74 - 546 mg kg(-1)), K (1.80 - 6.24 %), Ca (0.90 - 1.43 %), Mg (0. 17 - 0.67 %), Al (49 - 378 mg kg(-1)), Ba (15.53 - 69.84 mg kg(-1)) and B (34.7 - 56.5 mg kg(-1)).",
journal = "Journal of the Serbian Chemical Society",
title = "Inorganic analysis of herbal drugs. Part I. Metal determination in herbal drugs originating from medicinal plants of the family Lamiacae",
volume = "70",
number = "11",
pages = "1347-1355",
doi = "10.2298/JSC0511347R"
}

Ražić, S., Đogo, S., Slavković, L. J.,& Popović, A. R.. (2005). Inorganic analysis of herbal drugs. Part I. Metal determination in herbal drugs originating from medicinal plants of the family Lamiacae. in Journal of the Serbian Chemical Society, 70(11), 1347-1355.
https://doi.org/10.2298/JSC0511347R

Ražić S, Đogo S, Slavković LJ, Popović AR. Inorganic analysis of herbal drugs. Part I. Metal determination in herbal drugs originating from medicinal plants of the family Lamiacae. in Journal of the Serbian Chemical Society. 2005;70(11):1347-1355.
doi:10.2298/JSC0511347R .

Ražić, Slavica, Đogo, Svetlana, Slavković, Latinka J., Popović, Aleksandar R., "Inorganic analysis of herbal drugs. Part I. Metal determination in herbal drugs originating from medicinal plants of the family Lamiacae" in Journal of the Serbian Chemical Society, 70, no. 11 (2005):1347-1355,
https://doi.org/10.2298/JSC0511347R . .

TY  - CONF
AU  - Ražić, Slavica
AU  - Đogo, Svetlana
AU  - Slavković-Beškoski, Latinka J.
AU  - Popović, Aleksandar R.
PY  - 2004
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9580
AB  - In this paper trace (Cu and Zn) and minor (Mn and Fe) elements in some herbal drugs originating from the plants of the family Asteracae were determined by flame atomic absorption spectrometry. Chamomillae flos, Milefolii herba and Absinthii herba were analyzed taking into account their importance in phytotherapy in different diseases and disorders and the essentiality of mentioned elementsfor plantslife cycle. Validation of proposed method was performed by using CRM, NIST 1573a.
PB  - Society of Physical Chemists of Serbia
C3  - Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry
T1  - Trace and minor elements determination in some herbal drugs by faas
VL  - 2
SP  - 679
EP  - 681
UR  - https://hdl.handle.net/21.15107/rcub_vinar_9580
ER  - 

@conference{
author = "Ražić, Slavica and Đogo, Svetlana and Slavković-Beškoski, Latinka J. and Popović, Aleksandar R.",
year = "2004",
abstract = "In this paper trace (Cu and Zn) and minor (Mn and Fe) elements in some herbal drugs originating from the plants of the family Asteracae were determined by flame atomic absorption spectrometry. Chamomillae flos, Milefolii herba and Absinthii herba were analyzed taking into account their importance in phytotherapy in different diseases and disorders and the essentiality of mentioned elementsfor plantslife cycle. Validation of proposed method was performed by using CRM, NIST 1573a.",
publisher = "Society of Physical Chemists of Serbia",
journal = "Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry",
title = "Trace and minor elements determination in some herbal drugs by faas",
volume = "2",
pages = "679-681",
url = "https://hdl.handle.net/21.15107/rcub_vinar_9580"
}

Ražić, S., Đogo, S., Slavković-Beškoski, L. J.,& Popović, A. R.. (2004). Trace and minor elements determination in some herbal drugs by faas. in Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry
Society of Physical Chemists of Serbia., 2, 679-681.
https://hdl.handle.net/21.15107/rcub_vinar_9580

Ražić S, Đogo S, Slavković-Beškoski LJ, Popović AR. Trace and minor elements determination in some herbal drugs by faas. in Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry. 2004;2:679-681.
https://hdl.handle.net/21.15107/rcub_vinar_9580 .

Ražić, Slavica, Đogo, Svetlana, Slavković-Beškoski, Latinka J., Popović, Aleksandar R., "Trace and minor elements determination in some herbal drugs by faas" in Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry, 2 (2004):679-681,
https://hdl.handle.net/21.15107/rcub_vinar_9580 .

TY  - JOUR
AU  - Ražić, Slavica
AU  - Onjia, Antonije E.
AU  - Potkonjak, Branislav
PY  - 2003
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2687
AB  - Elemental composition of Echinacea purpurea (Asteracae), grown in Serbia under strongly controlled conditions, has been studied. To distinguish elemental patterns of different parts of the plant, the content of Zn, Fe, Cu, Mn, Ca, Mg, Sr, Ni, and Li in root versus upper plant parts were determined, by flame atomic absorption and flame atomic emission spectrometry. Analyses of the mentioned elements in soil and in an ethanolic extract of E. purpurea were made, too. The trace element data were evaluated by multivariate methods, i.e. principal component analysis and hierarchical cluster analysis. This revealed two groups of elements (I: Fe, Cu, Mn, Li; II: Ca, Mg, Zn, Ni), while trace element profiles of root. stem, leaves, and flowers of this plant differed significantly. However, no significant difference in the trace element patterns between the summer and the autumn harvest samples was found. (C) 2003 Elsevier B.V. All rights reserved.
T2  - Journal of Pharmaceutical and Biomedical Analysis
T1  - Trace elements analysis of Echinacea purpurea - herbal medicinal
VL  - 33
IS  - 4
SP  - 845
EP  - 850
DO  - 10.1016/S0731-7085(03)00338-8
ER  - 

@article{
author = "Ražić, Slavica and Onjia, Antonije E. and Potkonjak, Branislav",
year = "2003",
abstract = "Elemental composition of Echinacea purpurea (Asteracae), grown in Serbia under strongly controlled conditions, has been studied. To distinguish elemental patterns of different parts of the plant, the content of Zn, Fe, Cu, Mn, Ca, Mg, Sr, Ni, and Li in root versus upper plant parts were determined, by flame atomic absorption and flame atomic emission spectrometry. Analyses of the mentioned elements in soil and in an ethanolic extract of E. purpurea were made, too. The trace element data were evaluated by multivariate methods, i.e. principal component analysis and hierarchical cluster analysis. This revealed two groups of elements (I: Fe, Cu, Mn, Li; II: Ca, Mg, Zn, Ni), while trace element profiles of root. stem, leaves, and flowers of this plant differed significantly. However, no significant difference in the trace element patterns between the summer and the autumn harvest samples was found. (C) 2003 Elsevier B.V. All rights reserved.",
journal = "Journal of Pharmaceutical and Biomedical Analysis",
title = "Trace elements analysis of Echinacea purpurea - herbal medicinal",
volume = "33",
number = "4",
pages = "845-850",
doi = "10.1016/S0731-7085(03)00338-8"
}

Ražić, S., Onjia, A. E.,& Potkonjak, B.. (2003). Trace elements analysis of Echinacea purpurea - herbal medicinal. in Journal of Pharmaceutical and Biomedical Analysis, 33(4), 845-850.
https://doi.org/10.1016/S0731-7085(03)00338-8

Ražić S, Onjia AE, Potkonjak B. Trace elements analysis of Echinacea purpurea - herbal medicinal. in Journal of Pharmaceutical and Biomedical Analysis. 2003;33(4):845-850.
doi:10.1016/S0731-7085(03)00338-8 .

Ražić, Slavica, Onjia, Antonije E., Potkonjak, Branislav, "Trace elements analysis of Echinacea purpurea - herbal medicinal" in Journal of Pharmaceutical and Biomedical Analysis, 33, no. 4 (2003):845-850,
https://doi.org/10.1016/S0731-7085(03)00338-8 . .

TY  - JOUR
AU  - Holclajtner-Antunović, Ivanka D.
AU  - Ražić, Slavica
AU  - Todorović, M
AU  - Stoiljković, Milovan
PY  - 1999
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/6270
AB  - The effect of ethanol addition on the spectral line intensities of aluminium and excitation conditions in an argon stabilized d.c. are was investigated. In order to find optimal conditions for trace elements determination, some experimental parameters, important for analytical capabilities of this plasma source, such as current intensity, spectroscopic buffer concentration and concentration of ethanol in aqueous-ethanol mixtures, were determined. The influence of ethanol addition on the nebulization efficiency and physical properties of the mixtures analyzed was examined too. The increase in intensity of Al atomic line in the presence of ethanol in concentration up to 20 %, can be partly explained by higher nebulization efficiency. The other reason lies in the changes in the excitation and ionization processes, which was confirmed by the measurements of excitation temperature and electron number density.
T2  - Acta Chimica Hungarica
T1  - The influence of ethanol addition on excitation of aluminium in the argon stabilized d.c. arc
VL  - 136
IS  - 1-2
SP  - 83
EP  - 93
UR  - https://hdl.handle.net/21.15107/rcub_vinar_6270
ER  - 

@article{
author = "Holclajtner-Antunović, Ivanka D. and Ražić, Slavica and Todorović, M and Stoiljković, Milovan",
year = "1999",
abstract = "The effect of ethanol addition on the spectral line intensities of aluminium and excitation conditions in an argon stabilized d.c. are was investigated. In order to find optimal conditions for trace elements determination, some experimental parameters, important for analytical capabilities of this plasma source, such as current intensity, spectroscopic buffer concentration and concentration of ethanol in aqueous-ethanol mixtures, were determined. The influence of ethanol addition on the nebulization efficiency and physical properties of the mixtures analyzed was examined too. The increase in intensity of Al atomic line in the presence of ethanol in concentration up to 20 %, can be partly explained by higher nebulization efficiency. The other reason lies in the changes in the excitation and ionization processes, which was confirmed by the measurements of excitation temperature and electron number density.",
journal = "Acta Chimica Hungarica",
title = "The influence of ethanol addition on excitation of aluminium in the argon stabilized d.c. arc",
volume = "136",
number = "1-2",
pages = "83-93",
url = "https://hdl.handle.net/21.15107/rcub_vinar_6270"
}

Holclajtner-Antunović, I. D., Ražić, S., Todorović, M.,& Stoiljković, M.. (1999). The influence of ethanol addition on excitation of aluminium in the argon stabilized d.c. arc. in Acta Chimica Hungarica, 136(1-2), 83-93.
https://hdl.handle.net/21.15107/rcub_vinar_6270

Holclajtner-Antunović ID, Ražić S, Todorović M, Stoiljković M. The influence of ethanol addition on excitation of aluminium in the argon stabilized d.c. arc. in Acta Chimica Hungarica. 1999;136(1-2):83-93.
https://hdl.handle.net/21.15107/rcub_vinar_6270 .

Holclajtner-Antunović, Ivanka D., Ražić, Slavica, Todorović, M, Stoiljković, Milovan, "The influence of ethanol addition on excitation of aluminium in the argon stabilized d.c. arc" in Acta Chimica Hungarica, 136, no. 1-2 (1999):83-93,
https://hdl.handle.net/21.15107/rcub_vinar_6270 .

TY  - JOUR
AU  - Ražić, Slavica
AU  - Todorović, M
AU  - Holclajtner-Antunović, Ivanka D.
AU  - Stoiljković, Milovan
PY  - 1999
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2285
AB  - A spetroscopic method for the determination of metal traces (Mn, Cu, Fe) in wine has been developed based on argon stabilized d.c. are plasma at atmospheric pressure. The experimental conditions were optimized using lateral distributions of spectral line intensities of the trace elements in aqueous and ethanol-aqueous solutions. The method was applied to the analysis of 6 wines from 3 Serbian wine-growing regions. Direct and standard addition methods were tested. The precision of the method is characterized by a relative standard deviation of 0.50-3.00%. The accuracy of the method was assessed by flame AAS.
T2  - Fresenius Journal of Analytical Chemistry
T1  - Determination of metal traces in wine by argon stabilized d.c. arc
VL  - 365
IS  - 4
SP  - 367
EP  - 370
DO  - 10.1007/s002160051502
ER  - 

@article{
author = "Ražić, Slavica and Todorović, M and Holclajtner-Antunović, Ivanka D. and Stoiljković, Milovan",
year = "1999",
abstract = "A spetroscopic method for the determination of metal traces (Mn, Cu, Fe) in wine has been developed based on argon stabilized d.c. are plasma at atmospheric pressure. The experimental conditions were optimized using lateral distributions of spectral line intensities of the trace elements in aqueous and ethanol-aqueous solutions. The method was applied to the analysis of 6 wines from 3 Serbian wine-growing regions. Direct and standard addition methods were tested. The precision of the method is characterized by a relative standard deviation of 0.50-3.00%. The accuracy of the method was assessed by flame AAS.",
journal = "Fresenius Journal of Analytical Chemistry",
title = "Determination of metal traces in wine by argon stabilized d.c. arc",
volume = "365",
number = "4",
pages = "367-370",
doi = "10.1007/s002160051502"
}

Ražić, S., Todorović, M., Holclajtner-Antunović, I. D.,& Stoiljković, M.. (1999). Determination of metal traces in wine by argon stabilized d.c. arc. in Fresenius Journal of Analytical Chemistry, 365(4), 367-370.
https://doi.org/10.1007/s002160051502

Ražić S, Todorović M, Holclajtner-Antunović ID, Stoiljković M. Determination of metal traces in wine by argon stabilized d.c. arc. in Fresenius Journal of Analytical Chemistry. 1999;365(4):367-370.
doi:10.1007/s002160051502 .

Ražić, Slavica, Todorović, M, Holclajtner-Antunović, Ivanka D., Stoiljković, Milovan, "Determination of metal traces in wine by argon stabilized d.c. arc" in Fresenius Journal of Analytical Chemistry, 365, no. 4 (1999):367-370,
https://doi.org/10.1007/s002160051502 . .

TY  - JOUR
AU  - Ražić, Slavica
AU  - Todorovic, M
AU  - Holclajtner-Antunović, Ivanka D.
AU  - Ilić, Z.
PY  - 1996
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/7214
AB  - The effect of the addition of ethanol to aqueous solutions of various trace elements (Ca, Cd, Mg, Cu and Ni) on their spectral line intensities in inductively coupled argon plasma (ICAP) was investigated. Using a relatively low ethanol content (up to 10%, v/v) an enhancement of both atomic and ionic lines was found but to a different extent. By optimization of experimental parameters, an improvement of the sensitivity of the multielemental analysis was obtained.
T2  - Fresenius Journal of Analytical Chemistry
T1  - The influence of ethanol addition on the determination of trace elements in aqueous solutions by ICAP
VL  - 355
IS  - 3-4
SP  - 274
EP  - 276
UR  - https://hdl.handle.net/21.15107/rcub_vinar_7214
ER  - 

@article{
author = "Ražić, Slavica and Todorovic, M and Holclajtner-Antunović, Ivanka D. and Ilić, Z.",
year = "1996",
abstract = "The effect of the addition of ethanol to aqueous solutions of various trace elements (Ca, Cd, Mg, Cu and Ni) on their spectral line intensities in inductively coupled argon plasma (ICAP) was investigated. Using a relatively low ethanol content (up to 10%, v/v) an enhancement of both atomic and ionic lines was found but to a different extent. By optimization of experimental parameters, an improvement of the sensitivity of the multielemental analysis was obtained.",
journal = "Fresenius Journal of Analytical Chemistry",
title = "The influence of ethanol addition on the determination of trace elements in aqueous solutions by ICAP",
volume = "355",
number = "3-4",
pages = "274-276",
url = "https://hdl.handle.net/21.15107/rcub_vinar_7214"
}

Ražić, S., Todorovic, M., Holclajtner-Antunović, I. D.,& Ilić, Z.. (1996). The influence of ethanol addition on the determination of trace elements in aqueous solutions by ICAP. in Fresenius Journal of Analytical Chemistry, 355(3-4), 274-276.
https://hdl.handle.net/21.15107/rcub_vinar_7214

Ražić S, Todorovic M, Holclajtner-Antunović ID, Ilić Z. The influence of ethanol addition on the determination of trace elements in aqueous solutions by ICAP. in Fresenius Journal of Analytical Chemistry. 1996;355(3-4):274-276.
https://hdl.handle.net/21.15107/rcub_vinar_7214 .

Ražić, Slavica, Todorovic, M, Holclajtner-Antunović, Ivanka D., Ilić, Z., "The influence of ethanol addition on the determination of trace elements in aqueous solutions by ICAP" in Fresenius Journal of Analytical Chemistry, 355, no. 3-4 (1996):274-276,
https://hdl.handle.net/21.15107/rcub_vinar_7214 .