TY  - JOUR
AU  - Maćešić, Stevan
AU  - Čupić, Željko
AU  - Ivanović-Šašic, Ana
AU  - Anić, Slobodan
AU  - Radenković, Mirjana
AU  - Pejić, Nataša
AU  - Kolar-Anić, Ljiljana
PY  - 2018
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/1901
AB  - In this paper, we intend to show the importance of the bifurcation analysis in understanding of an oscillatory process. Hence, we use the bifurcation diagram of the Bray-Liebhafsky reaction performed in continuous well-stirred tank reactor under controlled temperature variations for the determination of the activation energies as well as rate constants of particular steps appearing in the kinetic model of oscillatory reaction mechanism. This approach has led us to the development of general procedure for treatment of experimentally obtained data and extracting kinetic parameters from them, which was very important considering that some rate constants of the already proposed model could not be determined experimentally and have to be fitted (or guessed). Also, the proposed approach has the potential to inspire the refinement of already proposed models and the development of a new one that will be able to reproduce experimentally obtained systems dynamical features more successfully. In particular, the dynamic states of the Bray-Liebhafsky oscillatory reaction have been analyzed experimentally and numerically using already proposed model together with qualitative and quantitative analysis of bifurcation diagrams in both cases.
T2  - Reaction Kinetics, Mechanisms and Catalysis
T1  - Bifurcation analysis: a tool for determining model parameters of the considered process
VL  - 123
IS  - 1
SP  - 31
EP  - 45
DO  - 10.1007/s11144-017-1324-6
ER  - 

@article{
author = "Maćešić, Stevan and Čupić, Željko and Ivanović-Šašic, Ana and Anić, Slobodan and Radenković, Mirjana and Pejić, Nataša and Kolar-Anić, Ljiljana",
year = "2018",
abstract = "In this paper, we intend to show the importance of the bifurcation analysis in understanding of an oscillatory process. Hence, we use the bifurcation diagram of the Bray-Liebhafsky reaction performed in continuous well-stirred tank reactor under controlled temperature variations for the determination of the activation energies as well as rate constants of particular steps appearing in the kinetic model of oscillatory reaction mechanism. This approach has led us to the development of general procedure for treatment of experimentally obtained data and extracting kinetic parameters from them, which was very important considering that some rate constants of the already proposed model could not be determined experimentally and have to be fitted (or guessed). Also, the proposed approach has the potential to inspire the refinement of already proposed models and the development of a new one that will be able to reproduce experimentally obtained systems dynamical features more successfully. In particular, the dynamic states of the Bray-Liebhafsky oscillatory reaction have been analyzed experimentally and numerically using already proposed model together with qualitative and quantitative analysis of bifurcation diagrams in both cases.",
journal = "Reaction Kinetics, Mechanisms and Catalysis",
title = "Bifurcation analysis: a tool for determining model parameters of the considered process",
volume = "123",
number = "1",
pages = "31-45",
doi = "10.1007/s11144-017-1324-6"
}

Maćešić, S., Čupić, Ž., Ivanović-Šašic, A., Anić, S., Radenković, M., Pejić, N.,& Kolar-Anić, L.. (2018). Bifurcation analysis: a tool for determining model parameters of the considered process. in Reaction Kinetics, Mechanisms and Catalysis, 123(1), 31-45.
https://doi.org/10.1007/s11144-017-1324-6

Maćešić S, Čupić Ž, Ivanović-Šašic A, Anić S, Radenković M, Pejić N, Kolar-Anić L. Bifurcation analysis: a tool for determining model parameters of the considered process. in Reaction Kinetics, Mechanisms and Catalysis. 2018;123(1):31-45.
doi:10.1007/s11144-017-1324-6 .

Maćešić, Stevan, Čupić, Željko, Ivanović-Šašic, Ana, Anić, Slobodan, Radenković, Mirjana, Pejić, Nataša, Kolar-Anić, Ljiljana, "Bifurcation analysis: a tool for determining model parameters of the considered process" in Reaction Kinetics, Mechanisms and Catalysis, 123, no. 1 (2018):31-45,
https://doi.org/10.1007/s11144-017-1324-6 . .

TY  - JOUR
AU  - Pejić, Nataša
AU  - Kolar-Anić, Ljiljana
AU  - Maksimović, Jelena
AU  - Janković, Marija M.
AU  - Vukojević, Vladana
AU  - Anić, Slobodan
PY  - 2016
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/1078
AB  - The temporal dynamics of the Bray-Liebhafsky reaction (iodate-based catalytic decomposition of hydrogen peroxide in an acidic aqueous solution) was experimentally characterized in a continuous stirred tank reactor by independently varying the temperature and the mixed inflow hydrogen peroxide concentration. When the temperature was the bifurcation parameter, the emergence/disappearance of oscillatory behavior via a supercritical Andronov-Hopf bifurcation was observed for different mixed inflow hydrogen peroxide concentrations. An increase in the mixed inflow hydrogen-peroxide concentration resulted in a shift of the bifurcation point towards higher values of temperature, but did not alter the bifurcation type.
PB  - Springer
T2  - Reaction Kinetics, Mechanisms and Catalysis
T1  - Dynamic transitions in the Bray-Liebhafsky oscillating reaction. Effect of hydrogen peroxide and temperature on bifurcation
VL  - 118
IS  - 1
SP  - 15
EP  - 26
DO  - 10.1007/s11144-016-0984-y
ER  - 

@article{
author = "Pejić, Nataša and Kolar-Anić, Ljiljana and Maksimović, Jelena and Janković, Marija M. and Vukojević, Vladana and Anić, Slobodan",
year = "2016",
abstract = "The temporal dynamics of the Bray-Liebhafsky reaction (iodate-based catalytic decomposition of hydrogen peroxide in an acidic aqueous solution) was experimentally characterized in a continuous stirred tank reactor by independently varying the temperature and the mixed inflow hydrogen peroxide concentration. When the temperature was the bifurcation parameter, the emergence/disappearance of oscillatory behavior via a supercritical Andronov-Hopf bifurcation was observed for different mixed inflow hydrogen peroxide concentrations. An increase in the mixed inflow hydrogen-peroxide concentration resulted in a shift of the bifurcation point towards higher values of temperature, but did not alter the bifurcation type.",
publisher = "Springer",
journal = "Reaction Kinetics, Mechanisms and Catalysis",
title = "Dynamic transitions in the Bray-Liebhafsky oscillating reaction. Effect of hydrogen peroxide and temperature on bifurcation",
volume = "118",
number = "1",
pages = "15-26",
doi = "10.1007/s11144-016-0984-y"
}

Pejić, N., Kolar-Anić, L., Maksimović, J., Janković, M. M., Vukojević, V.,& Anić, S.. (2016). Dynamic transitions in the Bray-Liebhafsky oscillating reaction. Effect of hydrogen peroxide and temperature on bifurcation. in Reaction Kinetics, Mechanisms and Catalysis
Springer., 118(1), 15-26.
https://doi.org/10.1007/s11144-016-0984-y

Pejić N, Kolar-Anić L, Maksimović J, Janković MM, Vukojević V, Anić S. Dynamic transitions in the Bray-Liebhafsky oscillating reaction. Effect of hydrogen peroxide and temperature on bifurcation. in Reaction Kinetics, Mechanisms and Catalysis. 2016;118(1):15-26.
doi:10.1007/s11144-016-0984-y .

Pejić, Nataša, Kolar-Anić, Ljiljana, Maksimović, Jelena, Janković, Marija M., Vukojević, Vladana, Anić, Slobodan, "Dynamic transitions in the Bray-Liebhafsky oscillating reaction. Effect of hydrogen peroxide and temperature on bifurcation" in Reaction Kinetics, Mechanisms and Catalysis, 118, no. 1 (2016):15-26,
https://doi.org/10.1007/s11144-016-0984-y . .

TY  - JOUR
AU  - Pejić, Nataša D.
AU  - Blagojević, Slavica M.
AU  - Sarap, Nataša
AU  - Maksimović, Jelena P.
AU  - Anić, SlobodanR.
AU  - Čupić, Željko
AU  - Kolar-Anić, Ljiljana Z.
PY  - 2014
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/5870
AB  - Perturbation of the BrayLiebhafsky non-oscillating subsystem (mixture of KIO3 and H2SO4), i.e., Dushman reaction (DR), by piroxicam (PX), was observed in an open reactor, i.e., in the continuously fed well-stirred tank reactor (CSTR). Monitoring the response of DR to perturbations by different concentrations of PX allows developing a simple procedure for quantitative determination of this analyte in both bulk drug and pharmaceutical preparation (injection). A tentative perturbation mechanism of PX action on the DR matrix, based on a kinetic scheme that was suggested by Agreda etal., is proposed. The PX reactivity in DR has been generally related to the reaction of PX with hypoiodous acid (HIO) present in the matrix.
T2  - Helvetica Chimica Acta
T1  - Perturbations of the Dushman Reaction with Piroxicam: Experimental and Model Calculations
VL  - 97
IS  - 1
SP  - 47
EP  - 55
DO  - 10.1002/hlca.201300109
ER  - 

@article{
author = "Pejić, Nataša D. and Blagojević, Slavica M. and Sarap, Nataša and Maksimović, Jelena P. and Anić, SlobodanR. and Čupić, Željko and Kolar-Anić, Ljiljana Z.",
year = "2014",
abstract = "Perturbation of the BrayLiebhafsky non-oscillating subsystem (mixture of KIO3 and H2SO4), i.e., Dushman reaction (DR), by piroxicam (PX), was observed in an open reactor, i.e., in the continuously fed well-stirred tank reactor (CSTR). Monitoring the response of DR to perturbations by different concentrations of PX allows developing a simple procedure for quantitative determination of this analyte in both bulk drug and pharmaceutical preparation (injection). A tentative perturbation mechanism of PX action on the DR matrix, based on a kinetic scheme that was suggested by Agreda etal., is proposed. The PX reactivity in DR has been generally related to the reaction of PX with hypoiodous acid (HIO) present in the matrix.",
journal = "Helvetica Chimica Acta",
title = "Perturbations of the Dushman Reaction with Piroxicam: Experimental and Model Calculations",
volume = "97",
number = "1",
pages = "47-55",
doi = "10.1002/hlca.201300109"
}

Pejić, N. D., Blagojević, S. M., Sarap, N., Maksimović, J. P., Anić, SlobodanR., Čupić, Ž.,& Kolar-Anić, L. Z.. (2014). Perturbations of the Dushman Reaction with Piroxicam: Experimental and Model Calculations. in Helvetica Chimica Acta, 97(1), 47-55.
https://doi.org/10.1002/hlca.201300109

Pejić ND, Blagojević SM, Sarap N, Maksimović JP, Anić S, Čupić Ž, Kolar-Anić LZ. Perturbations of the Dushman Reaction with Piroxicam: Experimental and Model Calculations. in Helvetica Chimica Acta. 2014;97(1):47-55.
doi:10.1002/hlca.201300109 .

Pejić, Nataša D., Blagojević, Slavica M., Sarap, Nataša, Maksimović, Jelena P., Anić, SlobodanR., Čupić, Željko, Kolar-Anić, Ljiljana Z., "Perturbations of the Dushman Reaction with Piroxicam: Experimental and Model Calculations" in Helvetica Chimica Acta, 97, no. 1 (2014):47-55,
https://doi.org/10.1002/hlca.201300109 . .

TY  - JOUR
AU  - Pejić, Nataša D.
AU  - Sarap, Nataša
AU  - Maksimović, Jelena P.
AU  - Anić, Slobodan R.
AU  - Kolar-Anić, Ljiljana Z.
PY  - 2013
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/5183
AB  - A simple and reliable novel kinetic method for the determination of piroxicam (PX) was proposed and validated. For quantitative determination of PX, the Bray-Liebhafsky (BL) oscillatory reaction was used in a stable non-equilibrium stationary state close to the bifurcation point. Under the optimized reaction conditions (T = 55.0A degrees C, [H2SO4](0) = 7.60x10(-2) mol L-1, [KIO3](0) = 5.90x10(-2) mol L-1, [H2O2](0) = 1.50x10(-1) mol L-1 and j (0) = 2.95x10(-2) min(-1)), the linear relationship between maximal potential shift Delta E (m) , and PX concentration was obtained in the concentration range 11.2-480.5 A mu g mL(-1) with a detection limit of 9.9 A mu g mL(-1). The method had a rather good sample throughput of 25 samples h(-1) with a precision RSD = 4.7% as well as recoveries RCV a parts per thousand currency sign 104.4%. Applicability of the proposed method to the direct determination of piroxicam in different pharmaceutical formulations (tablets, ampoules and gel) was demonstrated.
T2  - Central European Journal of Chemistry
T1  - Pulse perturbation technique for determination of piroxicam in pharmaceuticals using an oscillatory reaction system
VL  - 11
IS  - 2
SP  - 180
EP  - 188
DO  - 10.2478/s11532-012-0146-7
ER  - 

@article{
author = "Pejić, Nataša D. and Sarap, Nataša and Maksimović, Jelena P. and Anić, Slobodan R. and Kolar-Anić, Ljiljana Z.",
year = "2013",
abstract = "A simple and reliable novel kinetic method for the determination of piroxicam (PX) was proposed and validated. For quantitative determination of PX, the Bray-Liebhafsky (BL) oscillatory reaction was used in a stable non-equilibrium stationary state close to the bifurcation point. Under the optimized reaction conditions (T = 55.0A degrees C, [H2SO4](0) = 7.60x10(-2) mol L-1, [KIO3](0) = 5.90x10(-2) mol L-1, [H2O2](0) = 1.50x10(-1) mol L-1 and j (0) = 2.95x10(-2) min(-1)), the linear relationship between maximal potential shift Delta E (m) , and PX concentration was obtained in the concentration range 11.2-480.5 A mu g mL(-1) with a detection limit of 9.9 A mu g mL(-1). The method had a rather good sample throughput of 25 samples h(-1) with a precision RSD = 4.7% as well as recoveries RCV a parts per thousand currency sign 104.4%. Applicability of the proposed method to the direct determination of piroxicam in different pharmaceutical formulations (tablets, ampoules and gel) was demonstrated.",
journal = "Central European Journal of Chemistry",
title = "Pulse perturbation technique for determination of piroxicam in pharmaceuticals using an oscillatory reaction system",
volume = "11",
number = "2",
pages = "180-188",
doi = "10.2478/s11532-012-0146-7"
}

Pejić, N. D., Sarap, N., Maksimović, J. P., Anić, S. R.,& Kolar-Anić, L. Z.. (2013). Pulse perturbation technique for determination of piroxicam in pharmaceuticals using an oscillatory reaction system. in Central European Journal of Chemistry, 11(2), 180-188.
https://doi.org/10.2478/s11532-012-0146-7

Pejić ND, Sarap N, Maksimović JP, Anić SR, Kolar-Anić LZ. Pulse perturbation technique for determination of piroxicam in pharmaceuticals using an oscillatory reaction system. in Central European Journal of Chemistry. 2013;11(2):180-188.
doi:10.2478/s11532-012-0146-7 .

Pejić, Nataša D., Sarap, Nataša, Maksimović, Jelena P., Anić, Slobodan R., Kolar-Anić, Ljiljana Z., "Pulse perturbation technique for determination of piroxicam in pharmaceuticals using an oscillatory reaction system" in Central European Journal of Chemistry, 11, no. 2 (2013):180-188,
https://doi.org/10.2478/s11532-012-0146-7 . .

TY  - JOUR
AU  - Janković, Bojan Ž.
AU  - Adnađević, Borivoj
AU  - Kolar-Anić, Ljiljana
AU  - Smičiklas, Ivana D.
PY  - 2010
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/4022
AB  - The possibility of applying the Weibull mixture model for the fitting of the non-isothermal conversion data for the combustion process of animal bone samples has been investigated. It has been found that the conversion data at the different heating rates for the investigated samples, can be successfully described by the linear combination of few Weibull distribution functions. An optimal fitting of the conversion data has been obtained by a mixture of three Weibull distribution functions. It was established that the conversion curves calculated by the proposed model, are in good agreement with the raw conversion data of the investigated bone samples. The alterations of distribution parameters in the Weibull mixture model, indicate a probably change of the kinetic nature of the particular reaction stage. A model with a continuous distribution of the apparent activation energies (E-a) can adequately represents the individually stages of the complex combustion process. The characterization of the estimated distribution curves, enable us to receive the additional informations about the kinetic behaviour of individual reaction stages, which does not attainable from the results of conventional kinetic analysis. (C) 2010 Elsevier B.V. All rights reserved.
T2  - Thermochimica Acta
T1  - The non-isothermal thermogravimetric tests of animal bones combustion. Part II. Statistical analysis: Application of the Weibull mixture model
VL  - 505
IS  - 1-2
SP  - 98
EP  - 105
DO  - 10.1016/j.tca.2010.04.005
ER  - 

@article{
author = "Janković, Bojan Ž. and Adnađević, Borivoj and Kolar-Anić, Ljiljana and Smičiklas, Ivana D.",
year = "2010",
abstract = "The possibility of applying the Weibull mixture model for the fitting of the non-isothermal conversion data for the combustion process of animal bone samples has been investigated. It has been found that the conversion data at the different heating rates for the investigated samples, can be successfully described by the linear combination of few Weibull distribution functions. An optimal fitting of the conversion data has been obtained by a mixture of three Weibull distribution functions. It was established that the conversion curves calculated by the proposed model, are in good agreement with the raw conversion data of the investigated bone samples. The alterations of distribution parameters in the Weibull mixture model, indicate a probably change of the kinetic nature of the particular reaction stage. A model with a continuous distribution of the apparent activation energies (E-a) can adequately represents the individually stages of the complex combustion process. The characterization of the estimated distribution curves, enable us to receive the additional informations about the kinetic behaviour of individual reaction stages, which does not attainable from the results of conventional kinetic analysis. (C) 2010 Elsevier B.V. All rights reserved.",
journal = "Thermochimica Acta",
title = "The non-isothermal thermogravimetric tests of animal bones combustion. Part II. Statistical analysis: Application of the Weibull mixture model",
volume = "505",
number = "1-2",
pages = "98-105",
doi = "10.1016/j.tca.2010.04.005"
}

Janković, B. Ž., Adnađević, B., Kolar-Anić, L.,& Smičiklas, I. D.. (2010). The non-isothermal thermogravimetric tests of animal bones combustion. Part II. Statistical analysis: Application of the Weibull mixture model. in Thermochimica Acta, 505(1-2), 98-105.
https://doi.org/10.1016/j.tca.2010.04.005

Janković BŽ, Adnađević B, Kolar-Anić L, Smičiklas ID. The non-isothermal thermogravimetric tests of animal bones combustion. Part II. Statistical analysis: Application of the Weibull mixture model. in Thermochimica Acta. 2010;505(1-2):98-105.
doi:10.1016/j.tca.2010.04.005 .

Janković, Bojan Ž., Adnađević, Borivoj, Kolar-Anić, Ljiljana, Smičiklas, Ivana D., "The non-isothermal thermogravimetric tests of animal bones combustion. Part II. Statistical analysis: Application of the Weibull mixture model" in Thermochimica Acta, 505, no. 1-2 (2010):98-105,
https://doi.org/10.1016/j.tca.2010.04.005 . .

TY  - CONF
AU  - Marković, Vladimir
AU  - Jelić, Smiljana
AU  - Vukojević, Vesna
AU  - Kolar-Anić, Ljiljana
PY  - 2010
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9294
AB  - Glucocorticoids, the end products of the Hypothalamic-Pituitary-Adrenal (HPA)
axis, are widely used as anti-inflammatory and immunosuppressive drugs.
However, the feed-back effects of externally induced glucocorticoids on the HPA
axis activity remain widely unknown. In this study, we use numerical simulations
to investigate changes in the HPA axis activity caused by externally introduced
cortisol. We emulate the basal HPA activity using a stoichiometric model of the
HPA axis, and perturb its dynamics by abruptly changing cortisol levels during the
course of numerical integration, thereby mimicking cortisol increase under
treatment. Our study shows that the HPA axis activity is susceptible to
perturbations by cortisol and that external cortisol pulses elicit different responses,
depending on the dose and the time of cortisol introduction.
PB  - Society of Physical Chemists of Serbia
C3  - Physical chemistry 2010 : 10th international conference on fundamental and applied aspects of physical chemistry
T1  - Modelling the hypothalamic-pituitaryadrenal (hpa) axis response to external perturbations with cortisol
UR  - https://hdl.handle.net/21.15107/rcub_vinar_9294
ER  - 

@conference{
author = "Marković, Vladimir and Jelić, Smiljana and Vukojević, Vesna and Kolar-Anić, Ljiljana",
year = "2010",
abstract = "Glucocorticoids, the end products of the Hypothalamic-Pituitary-Adrenal (HPA)
axis, are widely used as anti-inflammatory and immunosuppressive drugs.
However, the feed-back effects of externally induced glucocorticoids on the HPA
axis activity remain widely unknown. In this study, we use numerical simulations
to investigate changes in the HPA axis activity caused by externally introduced
cortisol. We emulate the basal HPA activity using a stoichiometric model of the
HPA axis, and perturb its dynamics by abruptly changing cortisol levels during the
course of numerical integration, thereby mimicking cortisol increase under
treatment. Our study shows that the HPA axis activity is susceptible to
perturbations by cortisol and that external cortisol pulses elicit different responses,
depending on the dose and the time of cortisol introduction.",
publisher = "Society of Physical Chemists of Serbia",
journal = "Physical chemistry 2010 : 10th international conference on fundamental and applied aspects of physical chemistry",
title = "Modelling the hypothalamic-pituitaryadrenal (hpa) axis response to external perturbations with cortisol",
url = "https://hdl.handle.net/21.15107/rcub_vinar_9294"
}

Marković, V., Jelić, S., Vukojević, V.,& Kolar-Anić, L.. (2010). Modelling the hypothalamic-pituitaryadrenal (hpa) axis response to external perturbations with cortisol. in Physical chemistry 2010 : 10th international conference on fundamental and applied aspects of physical chemistry
Society of Physical Chemists of Serbia..
https://hdl.handle.net/21.15107/rcub_vinar_9294

Marković V, Jelić S, Vukojević V, Kolar-Anić L. Modelling the hypothalamic-pituitaryadrenal (hpa) axis response to external perturbations with cortisol. in Physical chemistry 2010 : 10th international conference on fundamental and applied aspects of physical chemistry. 2010;.
https://hdl.handle.net/21.15107/rcub_vinar_9294 .

Marković, Vladimir, Jelić, Smiljana, Vukojević, Vesna, Kolar-Anić, Ljiljana, "Modelling the hypothalamic-pituitaryadrenal (hpa) axis response to external perturbations with cortisol" in Physical chemistry 2010 : 10th international conference on fundamental and applied aspects of physical chemistry (2010),
https://hdl.handle.net/21.15107/rcub_vinar_9294 .

TY  - JOUR
AU  - Janković, Bojan Ž.
AU  - Kolar-Anić, Ljiljana
AU  - Smičiklas, Ivana D.
AU  - Dimović, Slavko
AU  - Arandelovic, Dragana
PY  - 2009
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3826
AB  - The non-isothermal combustion of animal bones was investigated by simultaneous thermogravimetric and differential thermal analysis (TG-DTA), in the temperature range Delta T = 20-650 degrees C. The full kinetic triplet (A, E(alpha) and f(alpha)) for the investigated process was established, using different calculation procedures: isoconversional (model-free) and the Kissingers methods. The non-isothermal process occured through three reaction stages (I, II and III). Stage I was described by a reaction model, which contains two competing reactions with different values of the apparent activation energy. The autocatalytic two-parameter Sestak-Berggren (SB) model (conversion function f(alpha) = alpha(0.62)(1-alpha)(3.22)). best described the second (II) reaction stage of bone samples. This stage, which corresponds to the degradation process of organic components (mainly collagen), exhibited the autocatalytic branching effect, with increasing complexity. Stage III, attributed to the combustion process of organic components, was best described by an n-th reaction order model with parameter n = 1.5 (f(alpha) = (1 - alpha()1.5). The appearance of compensation effect clearly showed the existence of three characteristic branches attributed to the dehydration, degradation and combustion processes, respectively, without noticable changes in mineral phase. The isothermal predictions of bone combustion process, at four different temperatures (T(iso) = 200, 300, 400 and 450 degrees C) were established in this paper. It was concluded that the shapes of the isothermal conversion curves at lower temperatures (200-300 degrees C) were similar, whereas became more complex with further temperature increase due to organic phase degradation. (C) 2009 Elsevier B.V. All rights reserved.
T2  - Thermochimica Acta
T1  - The non-isothermal thermogravimetric tests of animal bones combustion. Part. I. Kinetic analysis
VL  - 495
IS  - 1-2
SP  - 129
EP  - 138
DO  - 10.1016/j.tca.2009.06.016
ER  - 

@article{
author = "Janković, Bojan Ž. and Kolar-Anić, Ljiljana and Smičiklas, Ivana D. and Dimović, Slavko and Arandelovic, Dragana",
year = "2009",
abstract = "The non-isothermal combustion of animal bones was investigated by simultaneous thermogravimetric and differential thermal analysis (TG-DTA), in the temperature range Delta T = 20-650 degrees C. The full kinetic triplet (A, E(alpha) and f(alpha)) for the investigated process was established, using different calculation procedures: isoconversional (model-free) and the Kissingers methods. The non-isothermal process occured through three reaction stages (I, II and III). Stage I was described by a reaction model, which contains two competing reactions with different values of the apparent activation energy. The autocatalytic two-parameter Sestak-Berggren (SB) model (conversion function f(alpha) = alpha(0.62)(1-alpha)(3.22)). best described the second (II) reaction stage of bone samples. This stage, which corresponds to the degradation process of organic components (mainly collagen), exhibited the autocatalytic branching effect, with increasing complexity. Stage III, attributed to the combustion process of organic components, was best described by an n-th reaction order model with parameter n = 1.5 (f(alpha) = (1 - alpha()1.5). The appearance of compensation effect clearly showed the existence of three characteristic branches attributed to the dehydration, degradation and combustion processes, respectively, without noticable changes in mineral phase. The isothermal predictions of bone combustion process, at four different temperatures (T(iso) = 200, 300, 400 and 450 degrees C) were established in this paper. It was concluded that the shapes of the isothermal conversion curves at lower temperatures (200-300 degrees C) were similar, whereas became more complex with further temperature increase due to organic phase degradation. (C) 2009 Elsevier B.V. All rights reserved.",
journal = "Thermochimica Acta",
title = "The non-isothermal thermogravimetric tests of animal bones combustion. Part. I. Kinetic analysis",
volume = "495",
number = "1-2",
pages = "129-138",
doi = "10.1016/j.tca.2009.06.016"
}

Janković, B. Ž., Kolar-Anić, L., Smičiklas, I. D., Dimović, S.,& Arandelovic, D.. (2009). The non-isothermal thermogravimetric tests of animal bones combustion. Part. I. Kinetic analysis. in Thermochimica Acta, 495(1-2), 129-138.
https://doi.org/10.1016/j.tca.2009.06.016

Janković BŽ, Kolar-Anić L, Smičiklas ID, Dimović S, Arandelovic D. The non-isothermal thermogravimetric tests of animal bones combustion. Part. I. Kinetic analysis. in Thermochimica Acta. 2009;495(1-2):129-138.
doi:10.1016/j.tca.2009.06.016 .

Janković, Bojan Ž., Kolar-Anić, Ljiljana, Smičiklas, Ivana D., Dimović, Slavko, Arandelovic, Dragana, "The non-isothermal thermogravimetric tests of animal bones combustion. Part. I. Kinetic analysis" in Thermochimica Acta, 495, no. 1-2 (2009):129-138,
https://doi.org/10.1016/j.tca.2009.06.016 . .

TY  - JOUR
AU  - Jelić, Smiljana
AU  - Čupić, Željko
AU  - Kolar-Anić, Ljiljana
AU  - Vukojević, Vladana
PY  - 2009
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3974
AB  - Two methods for dynamic systems analysis, Stoichiometric Network Analysis (SNA) and Quenching of Small Amplitude Oscillations (QA), are used to study the behaviour of a vital biological system. Both methods use geometric approaches for the study of complex reaction systems. In SNA, methods based on convex polytopes geometry are applied for stability analysis and optimization of reaction networks. QA relies on a geometric representation of the concentration phase space, introduces the concept of manifolds and the singular perturbation theory to study the dynamics of complex processes. The analyzed system, the Hypothalamic-Pituitary-Adrenal (HPA) axis, as a major constituent of the neuroendocrine system has a critical role in integrating biological responses in basal conditions and during stress. Self-regulation in the HPA system was modeled through a positive and negative feedback effect of cortisol. A systematically reduced low-dimensional model of HPA activity in humans was fine-tuned by SNA, until quantitative agreement with experimental findings was achieved. By QA, we revealed an important dynamic regulatory mechanism that is a natural consequence of the intrinsic rhythmicity of the considered system.
T2  - International Journal of Nonlinear Sciences and Numerical Simulation
T1  - Predictive Modeling of the Hypothalamic-Pituitary-Adrenal (HPA) Function. Dynamic Systems Theory Approach by Stoichiometric Network Analysis and Quenching Small Amplitude Oscillations
VL  - 10
IS  - 11-12
SP  - 1451
EP  - 1472
UR  - https://hdl.handle.net/21.15107/rcub_vinar_3974
ER  - 

@article{
author = "Jelić, Smiljana and Čupić, Željko and Kolar-Anić, Ljiljana and Vukojević, Vladana",
year = "2009",
abstract = "Two methods for dynamic systems analysis, Stoichiometric Network Analysis (SNA) and Quenching of Small Amplitude Oscillations (QA), are used to study the behaviour of a vital biological system. Both methods use geometric approaches for the study of complex reaction systems. In SNA, methods based on convex polytopes geometry are applied for stability analysis and optimization of reaction networks. QA relies on a geometric representation of the concentration phase space, introduces the concept of manifolds and the singular perturbation theory to study the dynamics of complex processes. The analyzed system, the Hypothalamic-Pituitary-Adrenal (HPA) axis, as a major constituent of the neuroendocrine system has a critical role in integrating biological responses in basal conditions and during stress. Self-regulation in the HPA system was modeled through a positive and negative feedback effect of cortisol. A systematically reduced low-dimensional model of HPA activity in humans was fine-tuned by SNA, until quantitative agreement with experimental findings was achieved. By QA, we revealed an important dynamic regulatory mechanism that is a natural consequence of the intrinsic rhythmicity of the considered system.",
journal = "International Journal of Nonlinear Sciences and Numerical Simulation",
title = "Predictive Modeling of the Hypothalamic-Pituitary-Adrenal (HPA) Function. Dynamic Systems Theory Approach by Stoichiometric Network Analysis and Quenching Small Amplitude Oscillations",
volume = "10",
number = "11-12",
pages = "1451-1472",
url = "https://hdl.handle.net/21.15107/rcub_vinar_3974"
}

Jelić, S., Čupić, Ž., Kolar-Anić, L.,& Vukojević, V.. (2009). Predictive Modeling of the Hypothalamic-Pituitary-Adrenal (HPA) Function. Dynamic Systems Theory Approach by Stoichiometric Network Analysis and Quenching Small Amplitude Oscillations. in International Journal of Nonlinear Sciences and Numerical Simulation, 10(11-12), 1451-1472.
https://hdl.handle.net/21.15107/rcub_vinar_3974

Jelić S, Čupić Ž, Kolar-Anić L, Vukojević V. Predictive Modeling of the Hypothalamic-Pituitary-Adrenal (HPA) Function. Dynamic Systems Theory Approach by Stoichiometric Network Analysis and Quenching Small Amplitude Oscillations. in International Journal of Nonlinear Sciences and Numerical Simulation. 2009;10(11-12):1451-1472.
https://hdl.handle.net/21.15107/rcub_vinar_3974 .

Jelić, Smiljana, Čupić, Željko, Kolar-Anić, Ljiljana, Vukojević, Vladana, "Predictive Modeling of the Hypothalamic-Pituitary-Adrenal (HPA) Function. Dynamic Systems Theory Approach by Stoichiometric Network Analysis and Quenching Small Amplitude Oscillations" in International Journal of Nonlinear Sciences and Numerical Simulation, 10, no. 11-12 (2009):1451-1472,
https://hdl.handle.net/21.15107/rcub_vinar_3974 .

TY  - JOUR
AU  - Ivanović, A. Z.
AU  - Cupic, Z. D.
AU  - Janković, Marija M.
AU  - Kolar-Anić, Ljiljana
AU  - Anic, S. R.
PY  - 2008
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3533
AB  - Attractor reconstruction is done from the time series obtained by experimental investigation and by deterministic and stochastic simulation of the Bray-Liebhafsky oscillatory reaction. The appearance of deterministic chaos is confirmed and proven by both simulation and experiment, determining Lyapunov exponents for the sequences of flow rate values, as the control parameter. Moreover, unusual chaotic series were additionally recorded in the experiments, which cannot be found in deterministic numerical simulations. Therefore, an explanation of the difference between the dynamic behavior in the experiment and the deterministic simulation was sought and stochastic simulations based on the same reaction model were particularly useful. The. ne structure of the chaotic windows, derived from the analysis of deterministic simulations in the range of flow rate values, made the system highly susceptible to noise induced effects, in general.
T2  - Physical Chemistry Chemical Physics
T1  - The chaotic sequences in the Bray-Liebhafsky reaction in an open reactor
VL  - 10
IS  - 38
SP  - 5848
EP  - 5858
DO  - 10.1039/b804580a
ER  - 

@article{
author = "Ivanović, A. Z. and Cupic, Z. D. and Janković, Marija M. and Kolar-Anić, Ljiljana and Anic, S. R.",
year = "2008",
abstract = "Attractor reconstruction is done from the time series obtained by experimental investigation and by deterministic and stochastic simulation of the Bray-Liebhafsky oscillatory reaction. The appearance of deterministic chaos is confirmed and proven by both simulation and experiment, determining Lyapunov exponents for the sequences of flow rate values, as the control parameter. Moreover, unusual chaotic series were additionally recorded in the experiments, which cannot be found in deterministic numerical simulations. Therefore, an explanation of the difference between the dynamic behavior in the experiment and the deterministic simulation was sought and stochastic simulations based on the same reaction model were particularly useful. The. ne structure of the chaotic windows, derived from the analysis of deterministic simulations in the range of flow rate values, made the system highly susceptible to noise induced effects, in general.",
journal = "Physical Chemistry Chemical Physics",
title = "The chaotic sequences in the Bray-Liebhafsky reaction in an open reactor",
volume = "10",
number = "38",
pages = "5848-5858",
doi = "10.1039/b804580a"
}

Ivanović, A. Z., Cupic, Z. D., Janković, M. M., Kolar-Anić, L.,& Anic, S. R.. (2008). The chaotic sequences in the Bray-Liebhafsky reaction in an open reactor. in Physical Chemistry Chemical Physics, 10(38), 5848-5858.
https://doi.org/10.1039/b804580a

Ivanović AZ, Cupic ZD, Janković MM, Kolar-Anić L, Anic SR. The chaotic sequences in the Bray-Liebhafsky reaction in an open reactor. in Physical Chemistry Chemical Physics. 2008;10(38):5848-5858.
doi:10.1039/b804580a .

Ivanović, A. Z., Cupic, Z. D., Janković, Marija M., Kolar-Anić, Ljiljana, Anic, S. R., "The chaotic sequences in the Bray-Liebhafsky reaction in an open reactor" in Physical Chemistry Chemical Physics, 10, no. 38 (2008):5848-5858,
https://doi.org/10.1039/b804580a . .

TY  - CONF
AU  - Jelić, Smiljana
AU  - Čupić, Željko
AU  - Kolar-Anić, Ljiljana
PY  - 2006
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9416
AB  - The influence of the form of the periodic function that describes the circadian rhythm on the hypothalamic-pituitary-adrenal (HPA) system self-regulatory activity in humans is discussed. It was found that the HPA system is very sensitive to the choice of this function since it moderates the concentration of all species that are included in the model, as well as the form of ultradian pulses.
PB  - Society of Physical Chemists of Serbia
C3  - Physical chemistry 2006: 8th international conference on fundemental and applied aspract of physical chemistry
T1  - Influence of the form of the periodic function that describes the circadian rhythm of the hpa system activity
SP  - 264
EP  - 266
UR  - https://hdl.handle.net/21.15107/rcub_vinar_9416
ER  - 

@conference{
author = "Jelić, Smiljana and Čupić, Željko and Kolar-Anić, Ljiljana",
year = "2006",
abstract = "The influence of the form of the periodic function that describes the circadian rhythm on the hypothalamic-pituitary-adrenal (HPA) system self-regulatory activity in humans is discussed. It was found that the HPA system is very sensitive to the choice of this function since it moderates the concentration of all species that are included in the model, as well as the form of ultradian pulses.",
publisher = "Society of Physical Chemists of Serbia",
journal = "Physical chemistry 2006: 8th international conference on fundemental and applied aspract of physical chemistry",
title = "Influence of the form of the periodic function that describes the circadian rhythm of the hpa system activity",
pages = "264-266",
url = "https://hdl.handle.net/21.15107/rcub_vinar_9416"
}

Jelić, S., Čupić, Ž.,& Kolar-Anić, L.. (2006). Influence of the form of the periodic function that describes the circadian rhythm of the hpa system activity. in Physical chemistry 2006: 8th international conference on fundemental and applied aspract of physical chemistry
Society of Physical Chemists of Serbia., 264-266.
https://hdl.handle.net/21.15107/rcub_vinar_9416

Jelić S, Čupić Ž, Kolar-Anić L. Influence of the form of the periodic function that describes the circadian rhythm of the hpa system activity. in Physical chemistry 2006: 8th international conference on fundemental and applied aspract of physical chemistry. 2006;:264-266.
https://hdl.handle.net/21.15107/rcub_vinar_9416 .

Jelić, Smiljana, Čupić, Željko, Kolar-Anić, Ljiljana, "Influence of the form of the periodic function that describes the circadian rhythm of the hpa system activity" in Physical chemistry 2006: 8th international conference on fundemental and applied aspract of physical chemistry (2006):264-266,
https://hdl.handle.net/21.15107/rcub_vinar_9416 .