TY  - JOUR
AU  - Srđenović, Branislava U.
AU  - Slavic, Marija N.
AU  - Stankov, Karmen M.
AU  - Kladar, Nebojsa V.
AU  - Jović, Danica S.
AU  - Seke, Mariana
AU  - Bogdanović, Višnja V.
PY  - 2015
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/767
AB  - Fullerenol (C-60(OH)(24)) nanoparticles (FNP) have a significant role in biomedical research due to their numerous biological activities, some of which have cytoprotective and anti-oxidative properties. The aim of this study was to measure distribution of fullerenol nanoparticles and zeta potential in cell medium RPMI 1640 with 10% fetal bovine serum (FBS) and to investigate the influence of FNP on Chinese hamster ovary cells (CHO-K1) survival, as well as to determine the activity of three antioxidative enzymes: superoxide-dismutase, glutathione-reductase and glutathione-S-transferase in mitomycin C-treated cell line. Our investigation implies that FNP, as a strong antioxidant, influences the cellular redox state and enzyme activities and thus may reduce cell proliferation, which confirms that FNP could be exploited for its use as a cytoprotective agent.
T2  - Hemijska industrija
T1  - Size distribution of fullerenol nanoparticles in cell culture medium and their influence on antioxidative enzymes in Chinese hamster ovary cells
VL  - 69
IS  - 4
SP  - 425
EP  - 431
DO  - 10.2298/HEMIND131218054S
ER  - 

@article{
author = "Srđenović, Branislava U. and Slavic, Marija N. and Stankov, Karmen M. and Kladar, Nebojsa V. and Jović, Danica S. and Seke, Mariana and Bogdanović, Višnja V.",
year = "2015",
abstract = "Fullerenol (C-60(OH)(24)) nanoparticles (FNP) have a significant role in biomedical research due to their numerous biological activities, some of which have cytoprotective and anti-oxidative properties. The aim of this study was to measure distribution of fullerenol nanoparticles and zeta potential in cell medium RPMI 1640 with 10% fetal bovine serum (FBS) and to investigate the influence of FNP on Chinese hamster ovary cells (CHO-K1) survival, as well as to determine the activity of three antioxidative enzymes: superoxide-dismutase, glutathione-reductase and glutathione-S-transferase in mitomycin C-treated cell line. Our investigation implies that FNP, as a strong antioxidant, influences the cellular redox state and enzyme activities and thus may reduce cell proliferation, which confirms that FNP could be exploited for its use as a cytoprotective agent.",
journal = "Hemijska industrija",
title = "Size distribution of fullerenol nanoparticles in cell culture medium and their influence on antioxidative enzymes in Chinese hamster ovary cells",
volume = "69",
number = "4",
pages = "425-431",
doi = "10.2298/HEMIND131218054S"
}

Srđenović, B. U., Slavic, M. N., Stankov, K. M., Kladar, N. V., Jović, D. S., Seke, M.,& Bogdanović, V. V.. (2015). Size distribution of fullerenol nanoparticles in cell culture medium and their influence on antioxidative enzymes in Chinese hamster ovary cells. in Hemijska industrija, 69(4), 425-431.
https://doi.org/10.2298/HEMIND131218054S

Srđenović BU, Slavic MN, Stankov KM, Kladar NV, Jović DS, Seke M, Bogdanović VV. Size distribution of fullerenol nanoparticles in cell culture medium and their influence on antioxidative enzymes in Chinese hamster ovary cells. in Hemijska industrija. 2015;69(4):425-431.
doi:10.2298/HEMIND131218054S .

Srđenović, Branislava U., Slavic, Marija N., Stankov, Karmen M., Kladar, Nebojsa V., Jović, Danica S., Seke, Mariana, Bogdanović, Višnja V., "Size distribution of fullerenol nanoparticles in cell culture medium and their influence on antioxidative enzymes in Chinese hamster ovary cells" in Hemijska industrija, 69, no. 4 (2015):425-431,
https://doi.org/10.2298/HEMIND131218054S . .