Stanković, Vesna

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orcid::0000-0002-0394-0503
  • Stanković, Vesna (8)
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Author's Bibliography

Screen printed diamond electrode as efficient “point-of-care” platform for submicromolar determination of cytostatic drug in biological fluids and pharmaceutical product

Stanković, Dalibor M.; Milanović, Zorana; Švorc, Lubomir; Stanković, Vesna; Janković, Drina; Mirković, Marija D.; Vranješ-Đurić, Sanja

(2021)

TY  - JOUR
AU  - Stanković, Dalibor M.
AU  - Milanović, Zorana
AU  - Švorc, Lubomir
AU  - Stanković, Vesna
AU  - Janković, Drina
AU  - Mirković, Marija D.
AU  - Vranješ-Đurić, Sanja
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9543
AB  - This work presents advanced electrochemical platform based on screen printed diamond electrode (SPDE) system for the single drop “point-of-care” testing. Proposed approach was applied for the quantification of doxorubicin hydrochloride (DOX) in biological fluids and pharmaceutical product. Using a single drop (~30 μL) of the tested solution at the electrode surface, DOX showed high electroactivity over a wide range of pHs. In these conditions, single oval shaped, well-defined and pH dependent oxidation peak was observed in the potential range from 0.5 V to 1.3 V. In the reverse scan, two cathodic peaks, were noted – around 0.3 V and – 0.5 V. Similarly, first reduction peak was pH dependent, while second one was independent in the studied range. Experimental conditions for DOX quantification were optimized and natures of the electrode reactions were investigated. Working linear range obtained for DOX detection was from 0.1 to 2.5 μM. Diffusion controlled electrode reaction reveal long life time of the proposed electrode as well high potential for practical application. Developed procedure was successfully applied for the DOX analysis in biological fluids – urine and pharmaceutical formulation. Obtained results clearly indicated that given procedure can be easily implemented for pharmaceutical control and medical analysis, in both, laboratory and field conditions. © 2021 Elsevier B.V.
T2  - Diamond and Related Materials
T1  - Screen printed diamond electrode as efficient “point-of-care” platform for submicromolar determination of cytostatic drug in biological fluids and pharmaceutical product
VL  - 113
SP  - 108277
DO  - 10.1016/j.diamond.2021.108277
ER  - 
@article{
author = "Stanković, Dalibor M. and Milanović, Zorana and Švorc, Lubomir and Stanković, Vesna and Janković, Drina and Mirković, Marija D. and Vranješ-Đurić, Sanja",
year = "2021",
abstract = "This work presents advanced electrochemical platform based on screen printed diamond electrode (SPDE) system for the single drop “point-of-care” testing. Proposed approach was applied for the quantification of doxorubicin hydrochloride (DOX) in biological fluids and pharmaceutical product. Using a single drop (~30 μL) of the tested solution at the electrode surface, DOX showed high electroactivity over a wide range of pHs. In these conditions, single oval shaped, well-defined and pH dependent oxidation peak was observed in the potential range from 0.5 V to 1.3 V. In the reverse scan, two cathodic peaks, were noted – around 0.3 V and – 0.5 V. Similarly, first reduction peak was pH dependent, while second one was independent in the studied range. Experimental conditions for DOX quantification were optimized and natures of the electrode reactions were investigated. Working linear range obtained for DOX detection was from 0.1 to 2.5 μM. Diffusion controlled electrode reaction reveal long life time of the proposed electrode as well high potential for practical application. Developed procedure was successfully applied for the DOX analysis in biological fluids – urine and pharmaceutical formulation. Obtained results clearly indicated that given procedure can be easily implemented for pharmaceutical control and medical analysis, in both, laboratory and field conditions. © 2021 Elsevier B.V.",
journal = "Diamond and Related Materials",
title = "Screen printed diamond electrode as efficient “point-of-care” platform for submicromolar determination of cytostatic drug in biological fluids and pharmaceutical product",
volume = "113",
pages = "108277",
doi = "10.1016/j.diamond.2021.108277"
}
Stanković, D. M., Milanović, Z., Švorc, L., Stanković, V., Janković, D., Mirković, M. D.,& Vranješ-Đurić, S.. (2021). Screen printed diamond electrode as efficient “point-of-care” platform for submicromolar determination of cytostatic drug in biological fluids and pharmaceutical product. in Diamond and Related Materials, 113, 108277.
https://doi.org/10.1016/j.diamond.2021.108277
Stanković DM, Milanović Z, Švorc L, Stanković V, Janković D, Mirković MD, Vranješ-Đurić S. Screen printed diamond electrode as efficient “point-of-care” platform for submicromolar determination of cytostatic drug in biological fluids and pharmaceutical product. in Diamond and Related Materials. 2021;113:108277.
doi:10.1016/j.diamond.2021.108277 .
Stanković, Dalibor M., Milanović, Zorana, Švorc, Lubomir, Stanković, Vesna, Janković, Drina, Mirković, Marija D., Vranješ-Đurić, Sanja, "Screen printed diamond electrode as efficient “point-of-care” platform for submicromolar determination of cytostatic drug in biological fluids and pharmaceutical product" in Diamond and Related Materials, 113 (2021):108277,
https://doi.org/10.1016/j.diamond.2021.108277 . .
1
1
1

Evaluation of cytokine expression and circulating immune cell subsets as potential parameters of acute radiation toxicity in prostate cancer patients

Stanojković, Tatjana P.; Matić, Ivana Z.; Petrović, Nina; Stanković, Vesna; Kopčalić, Katarina; Besu, Irina; Đorđić Crnogorac, Marija; Mališić, Emina; Mirjačić-Martinović, Katarina; Vuletić, Ana; Bukumirić, Zoran; Žižak, Željko; Veldwijk, Marlon; Herskind, Carsten; Nikitović, Marina

(2020)

TY  - JOUR
AU  - Stanojković, Tatjana P.
AU  - Matić, Ivana Z.
AU  - Petrović, Nina
AU  - Stanković, Vesna
AU  - Kopčalić, Katarina
AU  - Besu, Irina
AU  - Đorđić Crnogorac, Marija
AU  - Mališić, Emina
AU  - Mirjačić-Martinović, Katarina
AU  - Vuletić, Ana
AU  - Bukumirić, Zoran
AU  - Žižak, Željko
AU  - Veldwijk, Marlon
AU  - Herskind, Carsten
AU  - Nikitović, Marina
PY  - 2020
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9713
AB  - One of the challenges of radiation oncology in the era of personalized medicine is identification of biomarkers associated with individual radiosensitivity. The aim of research was to evaluate the possible clinical value of the associations between clinical, physical, and biological factors, and risk for development of acute radiotoxicity in patients with prostate cancer. The study involved forty four patients treated with three-dimensional conformal radiotherapy. The concentrations of IL-1β, IL-2, IL-6, IFN-γ and TGF-β1 were assessed before radiotherapy, after 5th, 15th and 25th radiotherapy fractions, at the end, and 1 month after the end of radiotherapy. Cytokine gene expression was determined in peripheral blood mononuclear cells. The univariate analysis of circulating cytokine levels during radiotherapy showed that increased serum concentrations of IL-6 were significantly associated with higher grade of acute genitourinary toxicity. The multivariate analysis demonstrated that increased level of IL-6 during the radiotherapy was significantly associated with higher grade of acute genitourinary toxicity across treatment. TGF-β expression levels significantly decreased during course of radiotherapy. Research indicates that changes in circulating cytokine levels might be important parameter of radiotoxicity in patients with prostate cancer. These findings suggest that future studies based on multi-parameter examination are necessary for prediction of individual radiosensitivity.
T2  - Scientific Reports
T1  - Evaluation of cytokine expression and circulating immune cell subsets as potential parameters of acute radiation toxicity in prostate cancer patients
VL  - 10
IS  - 1
SP  - 19002
DO  - 10.1038/s41598-020-75812-0
ER  - 
@article{
author = "Stanojković, Tatjana P. and Matić, Ivana Z. and Petrović, Nina and Stanković, Vesna and Kopčalić, Katarina and Besu, Irina and Đorđić Crnogorac, Marija and Mališić, Emina and Mirjačić-Martinović, Katarina and Vuletić, Ana and Bukumirić, Zoran and Žižak, Željko and Veldwijk, Marlon and Herskind, Carsten and Nikitović, Marina",
year = "2020",
abstract = "One of the challenges of radiation oncology in the era of personalized medicine is identification of biomarkers associated with individual radiosensitivity. The aim of research was to evaluate the possible clinical value of the associations between clinical, physical, and biological factors, and risk for development of acute radiotoxicity in patients with prostate cancer. The study involved forty four patients treated with three-dimensional conformal radiotherapy. The concentrations of IL-1β, IL-2, IL-6, IFN-γ and TGF-β1 were assessed before radiotherapy, after 5th, 15th and 25th radiotherapy fractions, at the end, and 1 month after the end of radiotherapy. Cytokine gene expression was determined in peripheral blood mononuclear cells. The univariate analysis of circulating cytokine levels during radiotherapy showed that increased serum concentrations of IL-6 were significantly associated with higher grade of acute genitourinary toxicity. The multivariate analysis demonstrated that increased level of IL-6 during the radiotherapy was significantly associated with higher grade of acute genitourinary toxicity across treatment. TGF-β expression levels significantly decreased during course of radiotherapy. Research indicates that changes in circulating cytokine levels might be important parameter of radiotoxicity in patients with prostate cancer. These findings suggest that future studies based on multi-parameter examination are necessary for prediction of individual radiosensitivity.",
journal = "Scientific Reports",
title = "Evaluation of cytokine expression and circulating immune cell subsets as potential parameters of acute radiation toxicity in prostate cancer patients",
volume = "10",
number = "1",
pages = "19002",
doi = "10.1038/s41598-020-75812-0"
}
Stanojković, T. P., Matić, I. Z., Petrović, N., Stanković, V., Kopčalić, K., Besu, I., Đorđić Crnogorac, M., Mališić, E., Mirjačić-Martinović, K., Vuletić, A., Bukumirić, Z., Žižak, Ž., Veldwijk, M., Herskind, C.,& Nikitović, M.. (2020). Evaluation of cytokine expression and circulating immune cell subsets as potential parameters of acute radiation toxicity in prostate cancer patients. in Scientific Reports, 10(1), 19002.
https://doi.org/10.1038/s41598-020-75812-0
Stanojković TP, Matić IZ, Petrović N, Stanković V, Kopčalić K, Besu I, Đorđić Crnogorac M, Mališić E, Mirjačić-Martinović K, Vuletić A, Bukumirić Z, Žižak Ž, Veldwijk M, Herskind C, Nikitović M. Evaluation of cytokine expression and circulating immune cell subsets as potential parameters of acute radiation toxicity in prostate cancer patients. in Scientific Reports. 2020;10(1):19002.
doi:10.1038/s41598-020-75812-0 .
Stanojković, Tatjana P., Matić, Ivana Z., Petrović, Nina, Stanković, Vesna, Kopčalić, Katarina, Besu, Irina, Đorđić Crnogorac, Marija, Mališić, Emina, Mirjačić-Martinović, Katarina, Vuletić, Ana, Bukumirić, Zoran, Žižak, Željko, Veldwijk, Marlon, Herskind, Carsten, Nikitović, Marina, "Evaluation of cytokine expression and circulating immune cell subsets as potential parameters of acute radiation toxicity in prostate cancer patients" in Scientific Reports, 10, no. 1 (2020):19002,
https://doi.org/10.1038/s41598-020-75812-0 . .
1
1
1

Anti-human albumin monoclonal antibody immobilized on EDC-NHS functionalized carboxylic graphene/AuNPs composite as promising electrochemical HSA immunosensor

Stanković, Vesna; Đurđić, Slađana; Ognjanović, Miloš; Antić, Bratislav; Kalcher, Kurt; Mutić, Jelena J.; Stanković, Dalibor M.

(2020)

TY  - JOUR
AU  - Stanković, Vesna
AU  - Đurđić, Slađana
AU  - Ognjanović, Miloš
AU  - Antić, Bratislav
AU  - Kalcher, Kurt
AU  - Mutić, Jelena J.
AU  - Stanković, Dalibor M.
PY  - 2020
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8819
AB  - Diagnosis and treatment of some important diseased and metabolic disorders is based on successful detection of albumin. In this work, we aim to develop a simple immunosensor for the detection of human serum albumin in biological fluids. Anti-human albumin antibody was covalently attached to the activated surface of screen-printed carbon electrodes enriched with carboxyl graphene/gold nanoparticles composite. Microstructure (TEM, FE-SEM, XRD) and electrochemical (CV, EIS) characterization methods were used to investigate composite properties and to confirm the successful modification of the electrodes. Under the optimal conditions, linear working range and limit of detection were 2.5–500 μg/mL and 1.55 μg/mL, respectively. Additionally, the effect of some possibly interfering compounds was investigated and the immunosensor was used for real sample analysis. The results showed that the sensor exhibited accurate, precise and sensitive characteristics and can be promising replacement to the convention methods for albumin detection in clinical practice.
T2  - Journal of Electroanalytical Chemistry
T1  - Anti-human albumin monoclonal antibody immobilized on EDC-NHS functionalized carboxylic graphene/AuNPs composite as promising electrochemical HSA immunosensor
VL  - 860
SP  - 113928
DO  - 10.1016/j.jelechem.2020.113928
ER  - 
@article{
author = "Stanković, Vesna and Đurđić, Slađana and Ognjanović, Miloš and Antić, Bratislav and Kalcher, Kurt and Mutić, Jelena J. and Stanković, Dalibor M.",
year = "2020",
abstract = "Diagnosis and treatment of some important diseased and metabolic disorders is based on successful detection of albumin. In this work, we aim to develop a simple immunosensor for the detection of human serum albumin in biological fluids. Anti-human albumin antibody was covalently attached to the activated surface of screen-printed carbon electrodes enriched with carboxyl graphene/gold nanoparticles composite. Microstructure (TEM, FE-SEM, XRD) and electrochemical (CV, EIS) characterization methods were used to investigate composite properties and to confirm the successful modification of the electrodes. Under the optimal conditions, linear working range and limit of detection were 2.5–500 μg/mL and 1.55 μg/mL, respectively. Additionally, the effect of some possibly interfering compounds was investigated and the immunosensor was used for real sample analysis. The results showed that the sensor exhibited accurate, precise and sensitive characteristics and can be promising replacement to the convention methods for albumin detection in clinical practice.",
journal = "Journal of Electroanalytical Chemistry",
title = "Anti-human albumin monoclonal antibody immobilized on EDC-NHS functionalized carboxylic graphene/AuNPs composite as promising electrochemical HSA immunosensor",
volume = "860",
pages = "113928",
doi = "10.1016/j.jelechem.2020.113928"
}
Stanković, V., Đurđić, S., Ognjanović, M., Antić, B., Kalcher, K., Mutić, J. J.,& Stanković, D. M.. (2020). Anti-human albumin monoclonal antibody immobilized on EDC-NHS functionalized carboxylic graphene/AuNPs composite as promising electrochemical HSA immunosensor. in Journal of Electroanalytical Chemistry, 860, 113928.
https://doi.org/10.1016/j.jelechem.2020.113928
Stanković V, Đurđić S, Ognjanović M, Antić B, Kalcher K, Mutić JJ, Stanković DM. Anti-human albumin monoclonal antibody immobilized on EDC-NHS functionalized carboxylic graphene/AuNPs composite as promising electrochemical HSA immunosensor. in Journal of Electroanalytical Chemistry. 2020;860:113928.
doi:10.1016/j.jelechem.2020.113928 .
Stanković, Vesna, Đurđić, Slađana, Ognjanović, Miloš, Antić, Bratislav, Kalcher, Kurt, Mutić, Jelena J., Stanković, Dalibor M., "Anti-human albumin monoclonal antibody immobilized on EDC-NHS functionalized carboxylic graphene/AuNPs composite as promising electrochemical HSA immunosensor" in Journal of Electroanalytical Chemistry, 860 (2020):113928,
https://doi.org/10.1016/j.jelechem.2020.113928 . .
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Boron-doped diamond electrode as efficient sensing platform for simultaneous quantification of mefenamic acid and indomethacin

Petković, Branka B.; Ognjanović, Miloš; Krstić, Milena P.; Stanković, Vesna; Babincev, Ljiljana; Pergal, Marija V.; Stanković, Dalibor M.

(2020)

TY  - JOUR
AU  - Petković, Branka B.
AU  - Ognjanović, Miloš
AU  - Krstić, Milena P.
AU  - Stanković, Vesna
AU  - Babincev, Ljiljana
AU  - Pergal, Marija V.
AU  - Stanković, Dalibor M.
PY  - 2020
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8846
AB  - Mefenamic acid and indomethacin, medicaments belonging to the group of non-steroidal anti-inflammatory agents, were determined separately and simultaneously at anodically prepared BDDE. Differential pulse voltammetry was used to establish simple and fast analytical procedure based on electrooxidation of mefenamic acid at 0.6 V and indomethacin at 1.0 V (and 1.1 V). At optimal conditions, it was suitable for highly sensitive and selective determination of these compounds with LODs comparable to previously reported modified electrodes. Additionally, considering the importance of these compounds, we proposed precise and accurate quantification of these species based on green and simple pre-treatable electrochemical sensor. The effect of interfering agents (tablet ingredients and vitamins) was appeared to be negligibly confirming a favourable selectivity of the method. The proposed method was analytically applied by simultaneously determining mefenamic acid and indomethacin in pharmaceutical formulations. © 2020 Elsevier B.V.
T2  - Diamond and Related Materials
T1  - Boron-doped diamond electrode as efficient sensing platform for simultaneous quantification of mefenamic acid and indomethacin
VL  - 105
SP  - 107785
DO  - 10.1016/j.diamond.2020.107785
ER  - 
@article{
author = "Petković, Branka B. and Ognjanović, Miloš and Krstić, Milena P. and Stanković, Vesna and Babincev, Ljiljana and Pergal, Marija V. and Stanković, Dalibor M.",
year = "2020",
abstract = "Mefenamic acid and indomethacin, medicaments belonging to the group of non-steroidal anti-inflammatory agents, were determined separately and simultaneously at anodically prepared BDDE. Differential pulse voltammetry was used to establish simple and fast analytical procedure based on electrooxidation of mefenamic acid at 0.6 V and indomethacin at 1.0 V (and 1.1 V). At optimal conditions, it was suitable for highly sensitive and selective determination of these compounds with LODs comparable to previously reported modified electrodes. Additionally, considering the importance of these compounds, we proposed precise and accurate quantification of these species based on green and simple pre-treatable electrochemical sensor. The effect of interfering agents (tablet ingredients and vitamins) was appeared to be negligibly confirming a favourable selectivity of the method. The proposed method was analytically applied by simultaneously determining mefenamic acid and indomethacin in pharmaceutical formulations. © 2020 Elsevier B.V.",
journal = "Diamond and Related Materials",
title = "Boron-doped diamond electrode as efficient sensing platform for simultaneous quantification of mefenamic acid and indomethacin",
volume = "105",
pages = "107785",
doi = "10.1016/j.diamond.2020.107785"
}
Petković, B. B., Ognjanović, M., Krstić, M. P., Stanković, V., Babincev, L., Pergal, M. V.,& Stanković, D. M.. (2020). Boron-doped diamond electrode as efficient sensing platform for simultaneous quantification of mefenamic acid and indomethacin. in Diamond and Related Materials, 105, 107785.
https://doi.org/10.1016/j.diamond.2020.107785
Petković BB, Ognjanović M, Krstić MP, Stanković V, Babincev L, Pergal MV, Stanković DM. Boron-doped diamond electrode as efficient sensing platform for simultaneous quantification of mefenamic acid and indomethacin. in Diamond and Related Materials. 2020;105:107785.
doi:10.1016/j.diamond.2020.107785 .
Petković, Branka B., Ognjanović, Miloš, Krstić, Milena P., Stanković, Vesna, Babincev, Ljiljana, Pergal, Marija V., Stanković, Dalibor M., "Boron-doped diamond electrode as efficient sensing platform for simultaneous quantification of mefenamic acid and indomethacin" in Diamond and Related Materials, 105 (2020):107785,
https://doi.org/10.1016/j.diamond.2020.107785 . .
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TiO2/APTES cross-linked to carboxylic graphene based impedimetric glucose biosensor

Ognjanović, Miloš; Stanković, Vesna; Knežević, Sara; Antić, Bratislav; Vranješ-Đurić, Sanja; Stanković, Dalibor M.

(2020)

TY  - JOUR
AU  - Ognjanović, Miloš
AU  - Stanković, Vesna
AU  - Knežević, Sara
AU  - Antić, Bratislav
AU  - Vranješ-Đurić, Sanja
AU  - Stanković, Dalibor M.
PY  - 2020
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9040
AB  - Herein, we proposed a novel approach and state-of-the-art technology for the improvement of the materials and enzyme immobilization at the electrode surface and construction of impedimetric glucose biosensor. We silanized titanium dioxide nanoparticles using (3-aminopropyl)triethoxysilane (APTES), for the preparation of cross-linked material nanoparticles, with carboxylic graphene. The silanization of titanium dioxide nanoparticles and an increase in electron shuttle was proven feasible when this composite was able to achieve about 30% higher current than non-silanized material. The proposed approach was used for the modification of the printed three-electrode system and the development of the impedimetric glucose biosensor. The material morphology and electrochemical characteristics were confirmed by spectroscopic and electrochemical methods. The present combination effectively modified the electrode surface and serve as a promising basis for the construction of Point-of-Care devices. Developed biosensor possesses wide operating linear range toward glucose detection from 50 µmol to 1000 µmol, with the limit of detection of 24 µmol. Finally, negligible interference effect and application in the real sample indicate that the proposed mechanism can be successfully applied to the assessment of glucose level in only one drop of real sample.
T2  - Microchemical Journal
T1  - TiO2/APTES cross-linked to carboxylic graphene based impedimetric glucose biosensor
VL  - 158
SP  - 105150
DO  - 10.1016/j.microc.2020.105150
ER  - 
@article{
author = "Ognjanović, Miloš and Stanković, Vesna and Knežević, Sara and Antić, Bratislav and Vranješ-Đurić, Sanja and Stanković, Dalibor M.",
year = "2020",
abstract = "Herein, we proposed a novel approach and state-of-the-art technology for the improvement of the materials and enzyme immobilization at the electrode surface and construction of impedimetric glucose biosensor. We silanized titanium dioxide nanoparticles using (3-aminopropyl)triethoxysilane (APTES), for the preparation of cross-linked material nanoparticles, with carboxylic graphene. The silanization of titanium dioxide nanoparticles and an increase in electron shuttle was proven feasible when this composite was able to achieve about 30% higher current than non-silanized material. The proposed approach was used for the modification of the printed three-electrode system and the development of the impedimetric glucose biosensor. The material morphology and electrochemical characteristics were confirmed by spectroscopic and electrochemical methods. The present combination effectively modified the electrode surface and serve as a promising basis for the construction of Point-of-Care devices. Developed biosensor possesses wide operating linear range toward glucose detection from 50 µmol to 1000 µmol, with the limit of detection of 24 µmol. Finally, negligible interference effect and application in the real sample indicate that the proposed mechanism can be successfully applied to the assessment of glucose level in only one drop of real sample.",
journal = "Microchemical Journal",
title = "TiO2/APTES cross-linked to carboxylic graphene based impedimetric glucose biosensor",
volume = "158",
pages = "105150",
doi = "10.1016/j.microc.2020.105150"
}
Ognjanović, M., Stanković, V., Knežević, S., Antić, B., Vranješ-Đurić, S.,& Stanković, D. M.. (2020). TiO2/APTES cross-linked to carboxylic graphene based impedimetric glucose biosensor. in Microchemical Journal, 158, 105150.
https://doi.org/10.1016/j.microc.2020.105150
Ognjanović M, Stanković V, Knežević S, Antić B, Vranješ-Đurić S, Stanković DM. TiO2/APTES cross-linked to carboxylic graphene based impedimetric glucose biosensor. in Microchemical Journal. 2020;158:105150.
doi:10.1016/j.microc.2020.105150 .
Ognjanović, Miloš, Stanković, Vesna, Knežević, Sara, Antić, Bratislav, Vranješ-Đurić, Sanja, Stanković, Dalibor M., "TiO2/APTES cross-linked to carboxylic graphene based impedimetric glucose biosensor" in Microchemical Journal, 158 (2020):105150,
https://doi.org/10.1016/j.microc.2020.105150 . .
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A novel nonenzymatic hydrogen peroxide amperometric sensor based on AgNp@GNR nanocomposites modified screen-printed carbon electrode

Stanković, Vesna; Đurđić, Slađana Z.; Ognjanović, Miloš; Mutić, Jelena; Kalcher, Kurt; Stanković, Dalibor M.

(2020)

TY  - JOUR
AU  - Stanković, Vesna
AU  - Đurđić, Slađana Z.
AU  - Ognjanović, Miloš
AU  - Mutić, Jelena
AU  - Kalcher, Kurt
AU  - Stanković, Dalibor M.
PY  - 2020
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9111
AB  - A nonenzymatic hydrogen-peroxide sensor was developed by utilization of silver nanoparticles and graphene nanoribbons. The mentioned composite was inflicted on a screen-printed carbon electrode which provides disposable, ready-to-use sensor. The structure and morphology of the nanocomposite were analyzed by scanning electron microscopy and X-ray diffraction. The sensor has excellent performance toward H2O2 amperometric detection. Figures of merit include dynamic response range from 0.05 to 5 mM and detection limit of 20 μM (at S/N = 3). The fabricated sensor was used for the determination of H2O2 in milk samples. The obtained results showed that the proposed AgNp@GNR/SPCE sensor can be used for the determination of hydrogen peroxide in real samples.
T2  - Journal of Electroanalytical Chemistry
T1  - A novel nonenzymatic hydrogen peroxide amperometric sensor based on AgNp@GNR nanocomposites modified screen-printed carbon electrode
VL  - 876
SP  - 114487
DO  - 10.1016/j.jelechem.2020.114487
ER  - 
@article{
author = "Stanković, Vesna and Đurđić, Slađana Z. and Ognjanović, Miloš and Mutić, Jelena and Kalcher, Kurt and Stanković, Dalibor M.",
year = "2020",
abstract = "A nonenzymatic hydrogen-peroxide sensor was developed by utilization of silver nanoparticles and graphene nanoribbons. The mentioned composite was inflicted on a screen-printed carbon electrode which provides disposable, ready-to-use sensor. The structure and morphology of the nanocomposite were analyzed by scanning electron microscopy and X-ray diffraction. The sensor has excellent performance toward H2O2 amperometric detection. Figures of merit include dynamic response range from 0.05 to 5 mM and detection limit of 20 μM (at S/N = 3). The fabricated sensor was used for the determination of H2O2 in milk samples. The obtained results showed that the proposed AgNp@GNR/SPCE sensor can be used for the determination of hydrogen peroxide in real samples.",
journal = "Journal of Electroanalytical Chemistry",
title = "A novel nonenzymatic hydrogen peroxide amperometric sensor based on AgNp@GNR nanocomposites modified screen-printed carbon electrode",
volume = "876",
pages = "114487",
doi = "10.1016/j.jelechem.2020.114487"
}
Stanković, V., Đurđić, S. Z., Ognjanović, M., Mutić, J., Kalcher, K.,& Stanković, D. M.. (2020). A novel nonenzymatic hydrogen peroxide amperometric sensor based on AgNp@GNR nanocomposites modified screen-printed carbon electrode. in Journal of Electroanalytical Chemistry, 876, 114487.
https://doi.org/10.1016/j.jelechem.2020.114487
Stanković V, Đurđić SZ, Ognjanović M, Mutić J, Kalcher K, Stanković DM. A novel nonenzymatic hydrogen peroxide amperometric sensor based on AgNp@GNR nanocomposites modified screen-printed carbon electrode. in Journal of Electroanalytical Chemistry. 2020;876:114487.
doi:10.1016/j.jelechem.2020.114487 .
Stanković, Vesna, Đurđić, Slađana Z., Ognjanović, Miloš, Mutić, Jelena, Kalcher, Kurt, Stanković, Dalibor M., "A novel nonenzymatic hydrogen peroxide amperometric sensor based on AgNp@GNR nanocomposites modified screen-printed carbon electrode" in Journal of Electroanalytical Chemistry, 876 (2020):114487,
https://doi.org/10.1016/j.jelechem.2020.114487 . .
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Electrochemistry of the Arrow Poison, Tubocurarine, Using Boron Doped Diamond Electrode: Experimental and Theoretical Approaches

Đurđić, Slađana; Stanković, Vesna; Perić, Marko R.; Ognjanović, Miloš; Švorc, Lubomir; Mutić, Jelena J.; Stanković, Dalibor M.

(2019)

TY  - JOUR
AU  - Đurđić, Slađana
AU  - Stanković, Vesna
AU  - Perić, Marko R.
AU  - Ognjanović, Miloš
AU  - Švorc, Lubomir
AU  - Mutić, Jelena J.
AU  - Stanković, Dalibor M.
PY  - 2019
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/8615
AB  - In present work boron doped diamond (BDD) electrode was applied for studying electrochemical behavior, as well as for quantitative determination of natural alkaloid, tubocurarine (arrow poison/ TUB). Electrochemical behavior was investigated using several organic solvents and aqueous buffers, at different pHs, as supporting electrolytes. After selection of the most appropriate supporting electrolyte and investigation of its electrochemical behavior, analytical procedures for quantitative analysis of TUB were developed in an acetonitrile/methanol (80:20) mixture and in 1 mol L−1 nitric acid, which had linear quantification ranges from 4 × 10−6 to 1 × 10−4 mol L−1 (LOD = 3.07 × 10−6 mol L−1) and 4 × 10−6 to 9 × 10−5 mol L−1 (LOD = 2.45 × 10−6 mol L−1 and 5.28 × 10−7 mol L−1, depending on the selected peak), respectively. The oxidation mechanism of TUB was proposed from the theoretical aspect. Remarkable selectivity and good sensitivity were obtained after the TUB quantification method was optimized, allowing application of the developed method for TUB quantification in biological fluids, with excellent reproducibility, accuracy and precision.
T2  - Journal of The Electrochemical Society
T1  - Electrochemistry of the Arrow Poison, Tubocurarine, Using Boron Doped Diamond Electrode: Experimental and Theoretical Approaches
VL  - 166
IS  - 14
SP  - G157
EP  - G161
DO  - 10.1149/2.1241914jes
ER  - 
@article{
author = "Đurđić, Slađana and Stanković, Vesna and Perić, Marko R. and Ognjanović, Miloš and Švorc, Lubomir and Mutić, Jelena J. and Stanković, Dalibor M.",
year = "2019",
abstract = "In present work boron doped diamond (BDD) electrode was applied for studying electrochemical behavior, as well as for quantitative determination of natural alkaloid, tubocurarine (arrow poison/ TUB). Electrochemical behavior was investigated using several organic solvents and aqueous buffers, at different pHs, as supporting electrolytes. After selection of the most appropriate supporting electrolyte and investigation of its electrochemical behavior, analytical procedures for quantitative analysis of TUB were developed in an acetonitrile/methanol (80:20) mixture and in 1 mol L−1 nitric acid, which had linear quantification ranges from 4 × 10−6 to 1 × 10−4 mol L−1 (LOD = 3.07 × 10−6 mol L−1) and 4 × 10−6 to 9 × 10−5 mol L−1 (LOD = 2.45 × 10−6 mol L−1 and 5.28 × 10−7 mol L−1, depending on the selected peak), respectively. The oxidation mechanism of TUB was proposed from the theoretical aspect. Remarkable selectivity and good sensitivity were obtained after the TUB quantification method was optimized, allowing application of the developed method for TUB quantification in biological fluids, with excellent reproducibility, accuracy and precision.",
journal = "Journal of The Electrochemical Society",
title = "Electrochemistry of the Arrow Poison, Tubocurarine, Using Boron Doped Diamond Electrode: Experimental and Theoretical Approaches",
volume = "166",
number = "14",
pages = "G157-G161",
doi = "10.1149/2.1241914jes"
}
Đurđić, S., Stanković, V., Perić, M. R., Ognjanović, M., Švorc, L., Mutić, J. J.,& Stanković, D. M.. (2019). Electrochemistry of the Arrow Poison, Tubocurarine, Using Boron Doped Diamond Electrode: Experimental and Theoretical Approaches. in Journal of The Electrochemical Society, 166(14), G157-G161.
https://doi.org/10.1149/2.1241914jes
Đurđić S, Stanković V, Perić MR, Ognjanović M, Švorc L, Mutić JJ, Stanković DM. Electrochemistry of the Arrow Poison, Tubocurarine, Using Boron Doped Diamond Electrode: Experimental and Theoretical Approaches. in Journal of The Electrochemical Society. 2019;166(14):G157-G161.
doi:10.1149/2.1241914jes .
Đurđić, Slađana, Stanković, Vesna, Perić, Marko R., Ognjanović, Miloš, Švorc, Lubomir, Mutić, Jelena J., Stanković, Dalibor M., "Electrochemistry of the Arrow Poison, Tubocurarine, Using Boron Doped Diamond Electrode: Experimental and Theoretical Approaches" in Journal of The Electrochemical Society, 166, no. 14 (2019):G157-G161,
https://doi.org/10.1149/2.1241914jes . .
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Association between miR-21/146a/155 level changes and acute genitourinary radiotoxicity in prostate cancer patients: A pilot study

Kopčalić, Katarina; Petrović, Nina; Stanojković, Tatjana P.; Stanković, Vesna; Bukumirić, Zoran; Roganović, Jelena; Mališić, Emina; Nikitović, Marina

(2019)

TY  - JOUR
AU  - Kopčalić, Katarina
AU  - Petrović, Nina
AU  - Stanojković, Tatjana P.
AU  - Stanković, Vesna
AU  - Bukumirić, Zoran
AU  - Roganović, Jelena
AU  - Mališić, Emina
AU  - Nikitović, Marina
PY  - 2019
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/8444
AB  - Introduction: Nearly sixty percent of patients with prostate cancer (PCa) undergo radiation therapy (RT). During the course of treatment patients may experience normal tissue reactions. It is a well established fact that genetic and epigenetic mechanisms, such as microRNA (miRNA) level changes might be associated with radiotoxicity, as a response to irradiation. Materials and methods: This is the first study that has investigated levels of radiosensory miRNAs in association with acute genitourinary radiotoxicity extracted from peripheral blood mononuclear cells (PBCs), in three points; before RT (BRT), after RT (ART) and on the first control examination (FCONT). We measured levels of miR-21/146a/155 expression by quantitative real-time PCR (qRT-PCR), comparative ΔΔCt method, in fifteen patients with localized prostate cancer, treated with three-dimensional conformal radiotherapy (3DCRT). Nine subjects have experienced acute genitourinary (GU) radiotoxicity whereas six where without GU radiotoxicity. Results: Firstly, we detected the highest levels of miR-21 in ART group (p = 0.043) in the patients with acute GU radiotoxicity. Secondly, we found trend towards higher miR-21 levels and significantly higher levels of miR-146a/155 within the patients with acute GU toxicity than in patients without (p = 0.068, p = 0.016, and p = 0.010, respectively). Thirdly, we detected significant change in miR-146a/155 levels within the patients without acute GU radiotoxicity during RT p = 0.042, and p = 0.041, respectively). Conclusion: miR-21/146a/155 might be useful potential factors of radiosensitivity and acute genitourinary radiotoxicity in prostate cancer patients. miRNA might have great potential as predictors of various pathological conditions extracted from PBMCs. © 2018 Elsevier GmbH
T2  - Pathology - Research and Practice
T1  - Association between miR-21/146a/155 level changes and acute genitourinary radiotoxicity in prostate cancer patients: A pilot study
VL  - 215
IS  - 4
SP  - 626
EP  - 631
DO  - 10.1016/j.prp.2018.12.007
ER  - 
@article{
author = "Kopčalić, Katarina and Petrović, Nina and Stanojković, Tatjana P. and Stanković, Vesna and Bukumirić, Zoran and Roganović, Jelena and Mališić, Emina and Nikitović, Marina",
year = "2019",
abstract = "Introduction: Nearly sixty percent of patients with prostate cancer (PCa) undergo radiation therapy (RT). During the course of treatment patients may experience normal tissue reactions. It is a well established fact that genetic and epigenetic mechanisms, such as microRNA (miRNA) level changes might be associated with radiotoxicity, as a response to irradiation. Materials and methods: This is the first study that has investigated levels of radiosensory miRNAs in association with acute genitourinary radiotoxicity extracted from peripheral blood mononuclear cells (PBCs), in three points; before RT (BRT), after RT (ART) and on the first control examination (FCONT). We measured levels of miR-21/146a/155 expression by quantitative real-time PCR (qRT-PCR), comparative ΔΔCt method, in fifteen patients with localized prostate cancer, treated with three-dimensional conformal radiotherapy (3DCRT). Nine subjects have experienced acute genitourinary (GU) radiotoxicity whereas six where without GU radiotoxicity. Results: Firstly, we detected the highest levels of miR-21 in ART group (p = 0.043) in the patients with acute GU radiotoxicity. Secondly, we found trend towards higher miR-21 levels and significantly higher levels of miR-146a/155 within the patients with acute GU toxicity than in patients without (p = 0.068, p = 0.016, and p = 0.010, respectively). Thirdly, we detected significant change in miR-146a/155 levels within the patients without acute GU radiotoxicity during RT p = 0.042, and p = 0.041, respectively). Conclusion: miR-21/146a/155 might be useful potential factors of radiosensitivity and acute genitourinary radiotoxicity in prostate cancer patients. miRNA might have great potential as predictors of various pathological conditions extracted from PBMCs. © 2018 Elsevier GmbH",
journal = "Pathology - Research and Practice",
title = "Association between miR-21/146a/155 level changes and acute genitourinary radiotoxicity in prostate cancer patients: A pilot study",
volume = "215",
number = "4",
pages = "626-631",
doi = "10.1016/j.prp.2018.12.007"
}
Kopčalić, K., Petrović, N., Stanojković, T. P., Stanković, V., Bukumirić, Z., Roganović, J., Mališić, E.,& Nikitović, M.. (2019). Association between miR-21/146a/155 level changes and acute genitourinary radiotoxicity in prostate cancer patients: A pilot study. in Pathology - Research and Practice, 215(4), 626-631.
https://doi.org/10.1016/j.prp.2018.12.007
Kopčalić K, Petrović N, Stanojković TP, Stanković V, Bukumirić Z, Roganović J, Mališić E, Nikitović M. Association between miR-21/146a/155 level changes and acute genitourinary radiotoxicity in prostate cancer patients: A pilot study. in Pathology - Research and Practice. 2019;215(4):626-631.
doi:10.1016/j.prp.2018.12.007 .
Kopčalić, Katarina, Petrović, Nina, Stanojković, Tatjana P., Stanković, Vesna, Bukumirić, Zoran, Roganović, Jelena, Mališić, Emina, Nikitović, Marina, "Association between miR-21/146a/155 level changes and acute genitourinary radiotoxicity in prostate cancer patients: A pilot study" in Pathology - Research and Practice, 215, no. 4 (2019):626-631,
https://doi.org/10.1016/j.prp.2018.12.007 . .
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