Zmejkoski, Danica

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Authority KeyName Variants
orcid::0000-0001-9884-8832
  • Zmejkoski, Danica (8)
Projects
Synthesis, processing and characterization of nanostructured materials for application in the field of energy, mechanical engineering, environmental protection and biomedicine Study of structure-function relationships in the plant cell wall and modifications of the wall structure by enzyme engineering
Characterization and application of fungal metabolites and assessment of new biofungicides potential VEGA [2/0051/20]
COST Action [CA16217, ENIUS] COST [CA16217] “ENIUS”
The effects of magnetic fields and other environmental stressors on the physiological responses and behavior of different species The membranes as sites of interaction between the intracellular and apoplastic environments: studies of the bioenergetics and signaling using biophysical and biochemical techniques.
Identification of predictive molecular markers for cancer progression, response to therapy and disease outcome Functional, Functionalized and Advanced Nanomaterials
Zero- to Three-Dimensional Nanostructures for Application in Electronics and Renewable Energy Sources: Synthesis, Characterization and Processing Implementation and evaluation of a new molecular method for a quick detection of a mecA gene directly in swabs originated from humans, animals and their environment
Ministry of Education, Science and Technological Development of the Republic of Serbia [451-03-2/2020- 14/20-0302002] Ministry of Education, Science and Technological Development of the Republic of Serbia [451-03-2/2020-14/20-0302002]
Ministry of Education, Science and Technological Development of the Republic of Serbia [TR31079] National Academy of Sciences of Ukraine (47/2015-2016)

Author's Bibliography

Photoactive and antioxidant nanochitosan dots/biocellulose hydrogels for wound healing treatment

Zmejkoski, Danica; Marković, Zoran M.; Budimir, Milica; Zdravković, Nemanja M.; Trišić, Dijana D.; Bugárová, Nikol; Danko, Martin; Kozyrovska, Natalia O.; Špitalský, Zdeno; Kleinová, Angela; Kuzman, Sanja; Pavlović, Vladimir B.; Todorović-Marković, Biljana

(2021)

TY  - JOUR
AU  - Zmejkoski, Danica
AU  - Marković, Zoran M.
AU  - Budimir, Milica
AU  - Zdravković, Nemanja M.
AU  - Trišić, Dijana D.
AU  - Bugárová, Nikol
AU  - Danko, Martin
AU  - Kozyrovska, Natalia O.
AU  - Špitalský, Zdeno
AU  - Kleinová, Angela
AU  - Kuzman, Sanja
AU  - Pavlović, Vladimir B.
AU  - Todorović-Marković, Biljana
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9566
AB  - Bacterial infection and their resistance to known antibiotics delays wound healing. In this study, nanochitosan dots (nChiD) produced by gamma irradiation have been encapsulated in bacterial cellulose (BC) polymer matrix to study the antibacterial potentials of these nanocomposites and their possible usage in wound healing treatment (scratch assay). Detailed analyses show that nChiDs have disc-like shape and average diameter in the range of 40 to 60 nm depending of the applied dose. All nChiDs as well as BC-nChiD nanocomposites emit green photoluminescence independently on the excitation wavelengths. The new designed nanocomposites do not have a cytotoxic effect; antioxidant analysis shows their moderate radical scavenging activity whereas antibacterial properties show significant growth inhibition of strains mostly found in difficult-to-heal wounds. The obtained results confirm that new designed BC-nChiD nanocomposites might be potential agent in wound healing treatment. © 2021 Elsevier B.V.
T2  - Materials Science and Engineering: C
T1  - Photoactive and antioxidant nanochitosan dots/biocellulose hydrogels for wound healing treatment
VL  - 122
SP  - 111925
DO  - 10.1016/j.msec.2021.111925
ER  - 
@article{
author = "Zmejkoski, Danica and Marković, Zoran M. and Budimir, Milica and Zdravković, Nemanja M. and Trišić, Dijana D. and Bugárová, Nikol and Danko, Martin and Kozyrovska, Natalia O. and Špitalský, Zdeno and Kleinová, Angela and Kuzman, Sanja and Pavlović, Vladimir B. and Todorović-Marković, Biljana",
year = "2021",
abstract = "Bacterial infection and their resistance to known antibiotics delays wound healing. In this study, nanochitosan dots (nChiD) produced by gamma irradiation have been encapsulated in bacterial cellulose (BC) polymer matrix to study the antibacterial potentials of these nanocomposites and their possible usage in wound healing treatment (scratch assay). Detailed analyses show that nChiDs have disc-like shape and average diameter in the range of 40 to 60 nm depending of the applied dose. All nChiDs as well as BC-nChiD nanocomposites emit green photoluminescence independently on the excitation wavelengths. The new designed nanocomposites do not have a cytotoxic effect; antioxidant analysis shows their moderate radical scavenging activity whereas antibacterial properties show significant growth inhibition of strains mostly found in difficult-to-heal wounds. The obtained results confirm that new designed BC-nChiD nanocomposites might be potential agent in wound healing treatment. © 2021 Elsevier B.V.",
journal = "Materials Science and Engineering: C",
title = "Photoactive and antioxidant nanochitosan dots/biocellulose hydrogels for wound healing treatment",
volume = "122",
pages = "111925",
doi = "10.1016/j.msec.2021.111925"
}
Zmejkoski, D., Marković, Z. M., Budimir, M., Zdravković, N. M., Trišić, D. D., Bugárová, N., Danko, M., Kozyrovska, N. O., Špitalský, Z., Kleinová, A., Kuzman, S., Pavlović, V. B.,& Todorović-Marković, B.. (2021). Photoactive and antioxidant nanochitosan dots/biocellulose hydrogels for wound healing treatment. in Materials Science and Engineering: C, 122, 111925.
https://doi.org/10.1016/j.msec.2021.111925
Zmejkoski D, Marković ZM, Budimir M, Zdravković NM, Trišić DD, Bugárová N, Danko M, Kozyrovska NO, Špitalský Z, Kleinová A, Kuzman S, Pavlović VB, Todorović-Marković B. Photoactive and antioxidant nanochitosan dots/biocellulose hydrogels for wound healing treatment. in Materials Science and Engineering: C. 2021;122:111925.
doi:10.1016/j.msec.2021.111925 .
Zmejkoski, Danica, Marković, Zoran M., Budimir, Milica, Zdravković, Nemanja M., Trišić, Dijana D., Bugárová, Nikol, Danko, Martin, Kozyrovska, Natalia O., Špitalský, Zdeno, Kleinová, Angela, Kuzman, Sanja, Pavlović, Vladimir B., Todorović-Marković, Biljana, "Photoactive and antioxidant nanochitosan dots/biocellulose hydrogels for wound healing treatment" in Materials Science and Engineering: C, 122 (2021):111925,
https://doi.org/10.1016/j.msec.2021.111925 . .
1
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Bactericidal and antioxidant bacterial cellulose hydrogels doped with chitosan as potential urinary tract infection biomedical agent

Zmejkoski, Danica; Marković, Zoran M.; Zdravković, Nemanja M.; Trišić, Dijana D.; Budimir, Milica; Kuzman, Sanja; Kozyrovska, Natalia O.; Orlovska, Iryna V.; Bugárová, Nikol; Petrović, Đorđe; Kováčová, Mária; Kleinová, Angela; Špitalský, Zdeno; Pavlović, Vladimir B.; Todorović-Marković, Biljana

(2021)

TY  - JOUR
AU  - Zmejkoski, Danica
AU  - Marković, Zoran M.
AU  - Zdravković, Nemanja M.
AU  - Trišić, Dijana D.
AU  - Budimir, Milica
AU  - Kuzman, Sanja
AU  - Kozyrovska, Natalia O.
AU  - Orlovska, Iryna V.
AU  - Bugárová, Nikol
AU  - Petrović, Đorđe
AU  - Kováčová, Mária
AU  - Kleinová, Angela
AU  - Špitalský, Zdeno
AU  - Pavlović, Vladimir B.
AU  - Todorović-Marković, Biljana
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9143
AB  - Therapy of bacterial urinary tract infections (UTIs) and catheter associated urinary tract infections (CAUTIs) is still a great challenge because of the resistance of bacteria to nowadays used antibiotics and encrustation of catheters. Bacterial cellulose (BC) as a biocompatible material with a high porosity allows incorporation of different materials in its three dimensional network structure. In this work a low molecular weight chitosan (Chi) polymer is incorporated in BC with different concentrations. Different characterization techniques are used to investigate structural and optical properties of these composites. Radical scavenging activity test shows moderate antioxidant activity of these biocompatible composites whereasin vitrorelease test shows that 13.3% of chitosan is released after 72 h. Antibacterial testing of BC-Chi composites conducted on Gram-positive and Gram-negative bacteria causing UTIs and CAUTIs (Escherichia coli,Pseudomonas aeruginosa,Klebsiella pneumoniae) and encrustation (Proteus mirabilis) show bactericidal effect. The morphology analysis of bacteria after the application of BC-Chi shows that they are flattened with a rough surface, with a tendency to agglomerate and with decreased length and width. All obtained results show that BC-Chi composites might be considered as potential biomedical agents in treatment of UTIs and CAUTIs and as a urinary catheter coating in encrustation prevention.
T2  - RSC Advances
T1  - Bactericidal and antioxidant bacterial cellulose hydrogels doped with chitosan as potential urinary tract infection biomedical agent
VL  - 11
IS  - 15
SP  - 8559
EP  - 8568
DO  - 10.1039/D0RA10782D
ER  - 
@article{
author = "Zmejkoski, Danica and Marković, Zoran M. and Zdravković, Nemanja M. and Trišić, Dijana D. and Budimir, Milica and Kuzman, Sanja and Kozyrovska, Natalia O. and Orlovska, Iryna V. and Bugárová, Nikol and Petrović, Đorđe and Kováčová, Mária and Kleinová, Angela and Špitalský, Zdeno and Pavlović, Vladimir B. and Todorović-Marković, Biljana",
year = "2021",
abstract = "Therapy of bacterial urinary tract infections (UTIs) and catheter associated urinary tract infections (CAUTIs) is still a great challenge because of the resistance of bacteria to nowadays used antibiotics and encrustation of catheters. Bacterial cellulose (BC) as a biocompatible material with a high porosity allows incorporation of different materials in its three dimensional network structure. In this work a low molecular weight chitosan (Chi) polymer is incorporated in BC with different concentrations. Different characterization techniques are used to investigate structural and optical properties of these composites. Radical scavenging activity test shows moderate antioxidant activity of these biocompatible composites whereasin vitrorelease test shows that 13.3% of chitosan is released after 72 h. Antibacterial testing of BC-Chi composites conducted on Gram-positive and Gram-negative bacteria causing UTIs and CAUTIs (Escherichia coli,Pseudomonas aeruginosa,Klebsiella pneumoniae) and encrustation (Proteus mirabilis) show bactericidal effect. The morphology analysis of bacteria after the application of BC-Chi shows that they are flattened with a rough surface, with a tendency to agglomerate and with decreased length and width. All obtained results show that BC-Chi composites might be considered as potential biomedical agents in treatment of UTIs and CAUTIs and as a urinary catheter coating in encrustation prevention.",
journal = "RSC Advances",
title = "Bactericidal and antioxidant bacterial cellulose hydrogels doped with chitosan as potential urinary tract infection biomedical agent",
volume = "11",
number = "15",
pages = "8559-8568",
doi = "10.1039/D0RA10782D"
}
Zmejkoski, D., Marković, Z. M., Zdravković, N. M., Trišić, D. D., Budimir, M., Kuzman, S., Kozyrovska, N. O., Orlovska, I. V., Bugárová, N., Petrović, Đ., Kováčová, M., Kleinová, A., Špitalský, Z., Pavlović, V. B.,& Todorović-Marković, B.. (2021). Bactericidal and antioxidant bacterial cellulose hydrogels doped with chitosan as potential urinary tract infection biomedical agent. in RSC Advances, 11(15), 8559-8568.
https://doi.org/10.1039/D0RA10782D
Zmejkoski D, Marković ZM, Zdravković NM, Trišić DD, Budimir M, Kuzman S, Kozyrovska NO, Orlovska IV, Bugárová N, Petrović Đ, Kováčová M, Kleinová A, Špitalský Z, Pavlović VB, Todorović-Marković B. Bactericidal and antioxidant bacterial cellulose hydrogels doped with chitosan as potential urinary tract infection biomedical agent. in RSC Advances. 2021;11(15):8559-8568.
doi:10.1039/D0RA10782D .
Zmejkoski, Danica, Marković, Zoran M., Zdravković, Nemanja M., Trišić, Dijana D., Budimir, Milica, Kuzman, Sanja, Kozyrovska, Natalia O., Orlovska, Iryna V., Bugárová, Nikol, Petrović, Đorđe, Kováčová, Mária, Kleinová, Angela, Špitalský, Zdeno, Pavlović, Vladimir B., Todorović-Marković, Biljana, "Bactericidal and antioxidant bacterial cellulose hydrogels doped with chitosan as potential urinary tract infection biomedical agent" in RSC Advances, 11, no. 15 (2021):8559-8568,
https://doi.org/10.1039/D0RA10782D . .
1

Bacterial cellulose-lignin composite hydrogel as a promising agent in chronic wound healing

Zmejkoski, Danica; Spasojević, Dragica; Orlovska, Irina V.; Kozyrovska, Natalia O.; Soković, Marina; Glamočlija, Jasmina; Dmitrović, Svetlana; Matović, Branko; Tasić, Nikola B.; Maksimović, Vuk M.; Sosnin, Mikhail; Radotić, Ksenija

(2018)

TY  - JOUR
AU  - Zmejkoski, Danica
AU  - Spasojević, Dragica
AU  - Orlovska, Irina V.
AU  - Kozyrovska, Natalia O.
AU  - Soković, Marina
AU  - Glamočlija, Jasmina
AU  - Dmitrović, Svetlana
AU  - Matović, Branko
AU  - Tasić, Nikola B.
AU  - Maksimović, Vuk M.
AU  - Sosnin, Mikhail
AU  - Radotić, Ksenija
PY  - 2018
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/7769
AB  - Lignins and lignin-derived compounds are known to have antibacterial properties. The wound healing agents in the form of dressings produce faster skin repair and decrease pain in patients. In order to create an efficient antimicrobial agent in the form of dressing in the treatment of chronic wounds, a composite hydrogel of bacterial cellulose (BC) and dehydrogenative polymer of coniferyl alcohol (DHP), BC-DHP, was designed. Novel composite showed inhibitory or bactericidal effects against selected pathogenic bacteria, including clinically isolated ones. The highest release rate of DHP was in the first hour, while after 24 h there was still slow release of small amounts of DHP from BC-DHP during 72 h monitoring. High-performance liquid chromatography coupled with mass-spectrometry showed that BC-DHP releases DHP oligomers, which are proposed to be antimicrobially active DHP fractions. Scanning electron microscopy and atomic force microscopy micrographs proved a dose-dependent interaction of DHP with BC, which resulted in a decrease of the pore number and size in the cellulose membrane. The Fourier-transform infrared absorption spectra of the BC-DHP showed that DHP was partly bound to the BC matrix. The swelling and crystallinity degree were dose-dependent. All obtained results confirmed BC-DHP composite as a promising hydrogel for wounds healing.
T2  - International Journal of Biological Macromolecules
T1  - Bacterial cellulose-lignin composite hydrogel as a promising agent in chronic wound healing
VL  - 118
SP  - 494
EP  - 503
DO  - 10.1016/j.ijbiomac.2018.06.067
ER  - 
@article{
author = "Zmejkoski, Danica and Spasojević, Dragica and Orlovska, Irina V. and Kozyrovska, Natalia O. and Soković, Marina and Glamočlija, Jasmina and Dmitrović, Svetlana and Matović, Branko and Tasić, Nikola B. and Maksimović, Vuk M. and Sosnin, Mikhail and Radotić, Ksenija",
year = "2018",
abstract = "Lignins and lignin-derived compounds are known to have antibacterial properties. The wound healing agents in the form of dressings produce faster skin repair and decrease pain in patients. In order to create an efficient antimicrobial agent in the form of dressing in the treatment of chronic wounds, a composite hydrogel of bacterial cellulose (BC) and dehydrogenative polymer of coniferyl alcohol (DHP), BC-DHP, was designed. Novel composite showed inhibitory or bactericidal effects against selected pathogenic bacteria, including clinically isolated ones. The highest release rate of DHP was in the first hour, while after 24 h there was still slow release of small amounts of DHP from BC-DHP during 72 h monitoring. High-performance liquid chromatography coupled with mass-spectrometry showed that BC-DHP releases DHP oligomers, which are proposed to be antimicrobially active DHP fractions. Scanning electron microscopy and atomic force microscopy micrographs proved a dose-dependent interaction of DHP with BC, which resulted in a decrease of the pore number and size in the cellulose membrane. The Fourier-transform infrared absorption spectra of the BC-DHP showed that DHP was partly bound to the BC matrix. The swelling and crystallinity degree were dose-dependent. All obtained results confirmed BC-DHP composite as a promising hydrogel for wounds healing.",
journal = "International Journal of Biological Macromolecules",
title = "Bacterial cellulose-lignin composite hydrogel as a promising agent in chronic wound healing",
volume = "118",
pages = "494-503",
doi = "10.1016/j.ijbiomac.2018.06.067"
}
Zmejkoski, D., Spasojević, D., Orlovska, I. V., Kozyrovska, N. O., Soković, M., Glamočlija, J., Dmitrović, S., Matović, B., Tasić, N. B., Maksimović, V. M., Sosnin, M.,& Radotić, K.. (2018). Bacterial cellulose-lignin composite hydrogel as a promising agent in chronic wound healing. in International Journal of Biological Macromolecules, 118, 494-503.
https://doi.org/10.1016/j.ijbiomac.2018.06.067
Zmejkoski D, Spasojević D, Orlovska IV, Kozyrovska NO, Soković M, Glamočlija J, Dmitrović S, Matović B, Tasić NB, Maksimović VM, Sosnin M, Radotić K. Bacterial cellulose-lignin composite hydrogel as a promising agent in chronic wound healing. in International Journal of Biological Macromolecules. 2018;118:494-503.
doi:10.1016/j.ijbiomac.2018.06.067 .
Zmejkoski, Danica, Spasojević, Dragica, Orlovska, Irina V., Kozyrovska, Natalia O., Soković, Marina, Glamočlija, Jasmina, Dmitrović, Svetlana, Matović, Branko, Tasić, Nikola B., Maksimović, Vuk M., Sosnin, Mikhail, Radotić, Ksenija, "Bacterial cellulose-lignin composite hydrogel as a promising agent in chronic wound healing" in International Journal of Biological Macromolecules, 118 (2018):494-503,
https://doi.org/10.1016/j.ijbiomac.2018.06.067 . .
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Regenerative therapy for the nonhealing cutaneous wounds

Orlovska, Irina V.; Yakovenko, I. O.; Haidak, Andriy H.; Zmejkoski, Danica; Kozyrovska, Natalia O.

(2018)

TY  - JOUR
AU  - Orlovska, Irina V.
AU  - Yakovenko, I. O.
AU  - Haidak, Andriy H.
AU  - Zmejkoski, Danica
AU  - Kozyrovska, Natalia O.
PY  - 2018
UR  - http://biopolymers.org.ua/doi/10.7124/bc.000979
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/8029
AB  - Regenerative medicine therapy is inspired by current research advances in cellular biology, genetic engineering, synthetic biology, material sciences and so far contributes to the traditional therapy, making resistant diseases curable. Nowadays, chronic wound healing is possible due to cell-based regenerative technologies and recent non-cell therapeutic approaches. Here we review clinical applications of human stem cells, as well as cellular and tissue products as alternatives to the traditional therapy of non-healing wounds. The cell-based technologies for tissue regeneration and bioengineering utilize stem cells that are either injected into bloodstream or positioned directly into the target area. Cell-free regeneration technologies require either stem cell products, i.e., secretomes or their separate components, extracellular membrane vesicles, or tissue products. The stem cell therapies are designed to replace critically absent components of wounded or degenerative tissue. The stem cell secretome can promote the repair of damaged tissues independently of parent cells. Extracellular membrane vesicles mimic and recapitulate the mechanisms of stem cells in tissue regeneration and therefore might be promising for chronic wound and severe burns healing. The tissue products traditionally remain efficient wound healing remedies along with emerging advanced technologies. © 2018 I. V. Orlovska et al.
T2  - Biopolymers and Cell
T1  - Regenerative therapy for the nonhealing cutaneous wounds
VL  - 34
IS  - 3
SP  - 171
EP  - 195
DO  - 10.7124/bc.000979
ER  - 
@article{
author = "Orlovska, Irina V. and Yakovenko, I. O. and Haidak, Andriy H. and Zmejkoski, Danica and Kozyrovska, Natalia O.",
year = "2018",
abstract = "Regenerative medicine therapy is inspired by current research advances in cellular biology, genetic engineering, synthetic biology, material sciences and so far contributes to the traditional therapy, making resistant diseases curable. Nowadays, chronic wound healing is possible due to cell-based regenerative technologies and recent non-cell therapeutic approaches. Here we review clinical applications of human stem cells, as well as cellular and tissue products as alternatives to the traditional therapy of non-healing wounds. The cell-based technologies for tissue regeneration and bioengineering utilize stem cells that are either injected into bloodstream or positioned directly into the target area. Cell-free regeneration technologies require either stem cell products, i.e., secretomes or their separate components, extracellular membrane vesicles, or tissue products. The stem cell therapies are designed to replace critically absent components of wounded or degenerative tissue. The stem cell secretome can promote the repair of damaged tissues independently of parent cells. Extracellular membrane vesicles mimic and recapitulate the mechanisms of stem cells in tissue regeneration and therefore might be promising for chronic wound and severe burns healing. The tissue products traditionally remain efficient wound healing remedies along with emerging advanced technologies. © 2018 I. V. Orlovska et al.",
journal = "Biopolymers and Cell",
title = "Regenerative therapy for the nonhealing cutaneous wounds",
volume = "34",
number = "3",
pages = "171-195",
doi = "10.7124/bc.000979"
}
Orlovska, I. V., Yakovenko, I. O., Haidak, A. H., Zmejkoski, D.,& Kozyrovska, N. O.. (2018). Regenerative therapy for the nonhealing cutaneous wounds. in Biopolymers and Cell, 34(3), 171-195.
https://doi.org/10.7124/bc.000979
Orlovska IV, Yakovenko IO, Haidak AH, Zmejkoski D, Kozyrovska NO. Regenerative therapy for the nonhealing cutaneous wounds. in Biopolymers and Cell. 2018;34(3):171-195.
doi:10.7124/bc.000979 .
Orlovska, Irina V., Yakovenko, I. O., Haidak, Andriy H., Zmejkoski, Danica, Kozyrovska, Natalia O., "Regenerative therapy for the nonhealing cutaneous wounds" in Biopolymers and Cell, 34, no. 3 (2018):171-195,
https://doi.org/10.7124/bc.000979 . .

Different responses of Drosophila subobscura isofemale lines to extremely low frequency magnetic field (50Hz, 0.5mT): fitness components and locomotor activity

Zmejkoski, Danica; Petković, Branka; Pavkovic-Lucic, Sofija; Prolic, Zlatko; Anđelković, Marko; Savić, Tatjana

(2017)

TY  - JOUR
AU  - Zmejkoski, Danica
AU  - Petković, Branka
AU  - Pavkovic-Lucic, Sofija
AU  - Prolic, Zlatko
AU  - Anđelković, Marko
AU  - Savić, Tatjana
PY  - 2017
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/1540
AB  - Purpose: Extremely low frequency (ELF) magnetic fields as essential ecological factors may induce specific responses in genetically different lines. The object of this study was to investigate the impact of the ELF magnetic field on fitness components and locomotor activity of five Drosophila subobscura isofemale (IF) lines.Materials and methods: Each D. subobscura IF line, arbitrarily named: B16/1, B24/4, B39/1, B57/2 and B69/5, was maintained in five full-sib inbreeding generations. Their genetic structures were defined based on the mitochondrial DNA variability. Egg-first instar larvae and 1-day-old flies were exposed to an ELF magnetic field (50Hz, 0.5mT, 48h) and thereafter, fitness components and locomotor activity of males and females in an open field test were observed for each selected IF line, respectively.Results: Exposure of egg-first instar larvae to an ELF magnetic field shortened developmental time, and did not affect the viability and sex ratio of D. subobscura IF lines. Exposure of 1-day-old males and females IF lines B16/1 and B24/4 to an ELF magnetic field significantly decreased their locomotor activity and this effect lasted longer in females than males.Conclusions: These results indicate various responses of D. subobscura IF lines to the applied ELF magnetic field depending on their genetic background.
T2  - International Journal of Radiation Biology
T1  - Different responses of Drosophila subobscura isofemale lines to extremely low frequency magnetic field (50Hz, 0.5mT): fitness components and locomotor activity
VL  - 93
IS  - 5
SP  - 544
EP  - 552
DO  - 10.1080/09553002.2017.1268281
ER  - 
@article{
author = "Zmejkoski, Danica and Petković, Branka and Pavkovic-Lucic, Sofija and Prolic, Zlatko and Anđelković, Marko and Savić, Tatjana",
year = "2017",
abstract = "Purpose: Extremely low frequency (ELF) magnetic fields as essential ecological factors may induce specific responses in genetically different lines. The object of this study was to investigate the impact of the ELF magnetic field on fitness components and locomotor activity of five Drosophila subobscura isofemale (IF) lines.Materials and methods: Each D. subobscura IF line, arbitrarily named: B16/1, B24/4, B39/1, B57/2 and B69/5, was maintained in five full-sib inbreeding generations. Their genetic structures were defined based on the mitochondrial DNA variability. Egg-first instar larvae and 1-day-old flies were exposed to an ELF magnetic field (50Hz, 0.5mT, 48h) and thereafter, fitness components and locomotor activity of males and females in an open field test were observed for each selected IF line, respectively.Results: Exposure of egg-first instar larvae to an ELF magnetic field shortened developmental time, and did not affect the viability and sex ratio of D. subobscura IF lines. Exposure of 1-day-old males and females IF lines B16/1 and B24/4 to an ELF magnetic field significantly decreased their locomotor activity and this effect lasted longer in females than males.Conclusions: These results indicate various responses of D. subobscura IF lines to the applied ELF magnetic field depending on their genetic background.",
journal = "International Journal of Radiation Biology",
title = "Different responses of Drosophila subobscura isofemale lines to extremely low frequency magnetic field (50Hz, 0.5mT): fitness components and locomotor activity",
volume = "93",
number = "5",
pages = "544-552",
doi = "10.1080/09553002.2017.1268281"
}
Zmejkoski, D., Petković, B., Pavkovic-Lucic, S., Prolic, Z., Anđelković, M.,& Savić, T.. (2017). Different responses of Drosophila subobscura isofemale lines to extremely low frequency magnetic field (50Hz, 0.5mT): fitness components and locomotor activity. in International Journal of Radiation Biology, 93(5), 544-552.
https://doi.org/10.1080/09553002.2017.1268281
Zmejkoski D, Petković B, Pavkovic-Lucic S, Prolic Z, Anđelković M, Savić T. Different responses of Drosophila subobscura isofemale lines to extremely low frequency magnetic field (50Hz, 0.5mT): fitness components and locomotor activity. in International Journal of Radiation Biology. 2017;93(5):544-552.
doi:10.1080/09553002.2017.1268281 .
Zmejkoski, Danica, Petković, Branka, Pavkovic-Lucic, Sofija, Prolic, Zlatko, Anđelković, Marko, Savić, Tatjana, "Different responses of Drosophila subobscura isofemale lines to extremely low frequency magnetic field (50Hz, 0.5mT): fitness components and locomotor activity" in International Journal of Radiation Biology, 93, no. 5 (2017):544-552,
https://doi.org/10.1080/09553002.2017.1268281 . .
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Synthesis and characterization of spider silk calcite composite

Dmitrović, Svetlana; Jokić, Bojan M.; Prekajski, Marija D.; Pantić, Jelena R.; Zmejkoski, Danica; Zarubica, Aleksandra R.; Matović, Branko

(2016)

TY  - JOUR
AU  - Dmitrović, Svetlana
AU  - Jokić, Bojan M.
AU  - Prekajski, Marija D.
AU  - Pantić, Jelena R.
AU  - Zmejkoski, Danica
AU  - Zarubica, Aleksandra R.
AU  - Matović, Branko
PY  - 2016
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/1172
AB  - Spider silk poses excellent mechanical properties, tenacity and elasticity and it has been used as a template for calcite mineralization to improve load bearing strength of osteoconductive calcite. The samples were obtained by mimicking biomineralization for five days in order to follow formation and growth of calcite on the surface of spider silk. Crystal phase was detected by XRD and FTIR spectroscopy. Microstructure, crystal size and its morphology were studied by means of FESEM. After two days of processing, pure calcite phase was obtained, and a size of the formed crystals increased with prolongation of biomineralization.
T2  - Processing and Application of Ceramics
T1  - Synthesis and characterization of spider silk calcite composite
VL  - 10
IS  - 1
SP  - 37
EP  - 40
DO  - 10.2298/PAC1601037D
ER  - 
@article{
author = "Dmitrović, Svetlana and Jokić, Bojan M. and Prekajski, Marija D. and Pantić, Jelena R. and Zmejkoski, Danica and Zarubica, Aleksandra R. and Matović, Branko",
year = "2016",
abstract = "Spider silk poses excellent mechanical properties, tenacity and elasticity and it has been used as a template for calcite mineralization to improve load bearing strength of osteoconductive calcite. The samples were obtained by mimicking biomineralization for five days in order to follow formation and growth of calcite on the surface of spider silk. Crystal phase was detected by XRD and FTIR spectroscopy. Microstructure, crystal size and its morphology were studied by means of FESEM. After two days of processing, pure calcite phase was obtained, and a size of the formed crystals increased with prolongation of biomineralization.",
journal = "Processing and Application of Ceramics",
title = "Synthesis and characterization of spider silk calcite composite",
volume = "10",
number = "1",
pages = "37-40",
doi = "10.2298/PAC1601037D"
}
Dmitrović, S., Jokić, B. M., Prekajski, M. D., Pantić, J. R., Zmejkoski, D., Zarubica, A. R.,& Matović, B.. (2016). Synthesis and characterization of spider silk calcite composite. in Processing and Application of Ceramics, 10(1), 37-40.
https://doi.org/10.2298/PAC1601037D
Dmitrović S, Jokić BM, Prekajski MD, Pantić JR, Zmejkoski D, Zarubica AR, Matović B. Synthesis and characterization of spider silk calcite composite. in Processing and Application of Ceramics. 2016;10(1):37-40.
doi:10.2298/PAC1601037D .
Dmitrović, Svetlana, Jokić, Bojan M., Prekajski, Marija D., Pantić, Jelena R., Zmejkoski, Danica, Zarubica, Aleksandra R., Matović, Branko, "Synthesis and characterization of spider silk calcite composite" in Processing and Application of Ceramics, 10, no. 1 (2016):37-40,
https://doi.org/10.2298/PAC1601037D . .
3
3
3

Lignin model compound in alginate hydrogel: a strong antimicrobial agent with high potential in wound treatment

Spasojević, Dragica; Zmejkoski, Danica; Glamočlija, Jasmina; Nikolic, Milos; Soković, Marina; Milosevic, Verica; Jaric, Ivana; Stojanovic, Marijana; Marinkovic, Emilija; Barisani-Asenbauer, Talin; Prodanovic, Radivoje; Jovanovic, Milos; Radotić, Ksenija

(2016)

TY  - JOUR
AU  - Spasojević, Dragica
AU  - Zmejkoski, Danica
AU  - Glamočlija, Jasmina
AU  - Nikolic, Milos
AU  - Soković, Marina
AU  - Milosevic, Verica
AU  - Jaric, Ivana
AU  - Stojanovic, Marijana
AU  - Marinkovic, Emilija
AU  - Barisani-Asenbauer, Talin
AU  - Prodanovic, Radivoje
AU  - Jovanovic, Milos
AU  - Radotić, Ksenija
PY  - 2016
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/1336
AB  - Nowadays bacterial resistance to known antibiotics is a serious health problem. In order to achieve more efficient treatment, lately there is an effort to find new substances, such as certain biomaterials, that are non-toxic to humans with antibiotic potential. Lignins and lignin-derived compounds have been proposed to be good candidates for use in medicine and health maintenance. In this study, the antibacterial activity of the lignin model polymer dehydrogenate polymer (DHP) in alginate hydrogel (Alg) was studied. The obtained results show that DHP-Alg has strong antimicrobial activity against several bacterial strains and biofilms and does not have a toxic effect on human epithelial cells. These results strongly suggest its application as a wound healing agent or as an adjunct substance for wound treatments. (C) 2016 Elsevier B.V. and International Society of Chemotherapy. All rights reserved.
T2  - International Journal of Antimicrobial Agents
T1  - Lignin model compound in alginate hydrogel: a strong antimicrobial agent with high potential in wound treatment
VL  - 48
IS  - 6
SP  - 732
EP  - 735
DO  - 10.1016/j.ijantimicag.2016.08.014
ER  - 
@article{
author = "Spasojević, Dragica and Zmejkoski, Danica and Glamočlija, Jasmina and Nikolic, Milos and Soković, Marina and Milosevic, Verica and Jaric, Ivana and Stojanovic, Marijana and Marinkovic, Emilija and Barisani-Asenbauer, Talin and Prodanovic, Radivoje and Jovanovic, Milos and Radotić, Ksenija",
year = "2016",
abstract = "Nowadays bacterial resistance to known antibiotics is a serious health problem. In order to achieve more efficient treatment, lately there is an effort to find new substances, such as certain biomaterials, that are non-toxic to humans with antibiotic potential. Lignins and lignin-derived compounds have been proposed to be good candidates for use in medicine and health maintenance. In this study, the antibacterial activity of the lignin model polymer dehydrogenate polymer (DHP) in alginate hydrogel (Alg) was studied. The obtained results show that DHP-Alg has strong antimicrobial activity against several bacterial strains and biofilms and does not have a toxic effect on human epithelial cells. These results strongly suggest its application as a wound healing agent or as an adjunct substance for wound treatments. (C) 2016 Elsevier B.V. and International Society of Chemotherapy. All rights reserved.",
journal = "International Journal of Antimicrobial Agents",
title = "Lignin model compound in alginate hydrogel: a strong antimicrobial agent with high potential in wound treatment",
volume = "48",
number = "6",
pages = "732-735",
doi = "10.1016/j.ijantimicag.2016.08.014"
}
Spasojević, D., Zmejkoski, D., Glamočlija, J., Nikolic, M., Soković, M., Milosevic, V., Jaric, I., Stojanovic, M., Marinkovic, E., Barisani-Asenbauer, T., Prodanovic, R., Jovanovic, M.,& Radotić, K.. (2016). Lignin model compound in alginate hydrogel: a strong antimicrobial agent with high potential in wound treatment. in International Journal of Antimicrobial Agents, 48(6), 732-735.
https://doi.org/10.1016/j.ijantimicag.2016.08.014
Spasojević D, Zmejkoski D, Glamočlija J, Nikolic M, Soković M, Milosevic V, Jaric I, Stojanovic M, Marinkovic E, Barisani-Asenbauer T, Prodanovic R, Jovanovic M, Radotić K. Lignin model compound in alginate hydrogel: a strong antimicrobial agent with high potential in wound treatment. in International Journal of Antimicrobial Agents. 2016;48(6):732-735.
doi:10.1016/j.ijantimicag.2016.08.014 .
Spasojević, Dragica, Zmejkoski, Danica, Glamočlija, Jasmina, Nikolic, Milos, Soković, Marina, Milosevic, Verica, Jaric, Ivana, Stojanovic, Marijana, Marinkovic, Emilija, Barisani-Asenbauer, Talin, Prodanovic, Radivoje, Jovanovic, Milos, Radotić, Ksenija, "Lignin model compound in alginate hydrogel: a strong antimicrobial agent with high potential in wound treatment" in International Journal of Antimicrobial Agents, 48, no. 6 (2016):732-735,
https://doi.org/10.1016/j.ijantimicag.2016.08.014 . .
24
19
19

Anti-cancer effects of cerium oxide nanoparticles and its intracellular redox activity

Pešić, Milica; Podolski-Renić, Ana; Stojković, Sonja; Matović, Branko; Zmejkoski, Danica; Kojić, Vesna; Bogdanović, Gordana; Pavicevic, Aleksandra; Mojovic, Milos; Savić, Aleksandar; Milenković, Ivana; Kalauzi, Aleksandar; Radotić, Ksenija

(2015)

TY  - JOUR
AU  - Pešić, Milica
AU  - Podolski-Renić, Ana
AU  - Stojković, Sonja
AU  - Matović, Branko
AU  - Zmejkoski, Danica
AU  - Kojić, Vesna
AU  - Bogdanović, Gordana
AU  - Pavicevic, Aleksandra
AU  - Mojovic, Milos
AU  - Savić, Aleksandar
AU  - Milenković, Ivana
AU  - Kalauzi, Aleksandar
AU  - Radotić, Ksenija
PY  - 2015
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/519
AB  - Data on medical applications of cerium oxide nanoparticles CeO2 (CONP) are promising, yet information regarding their action in cells is incomplete and there are conflicting reports about in vitro toxicity. Herein, we have studied cytotoxic effect of CONP in several cancer and normal cell lines and their potential to change intracellular redox status. The IC50 was achieved only in two of eight tested cell lines, melanoma 518A2 and colorectal adenocarcinoma HT-29. Self-propagating room temperature method was applied to produce CONP with an average crystalline size of 4 nm. The results confirmed presence of Ce3+ and O2- vacancies. The induction of cell death by CONP and the production of reactive oxygen species (ROS) were analyzed by flow-cytometry. Free radicals related antioxidant capacity of the cells was studied by the reduction of stable free radical TEMPONE using electron spin resonance spectroscopy. CONP showed low or moderate cytotoxicity in cancer cell lines: adenocarcinoma DLD1 and multi-drug resistant DLD1-TxR, non-small cell lung carcinoma NCI-H460 and multi-drug resistant NCI-H460/R, while normal cell lines (keratinocytes HaCaT, lung fetal fibroblasts MRC-5) were insensitive. The most sensitive were 518A2 melanoma and HT-29 colorectal adenocarcinoma cell lines, with the IC50 values being between 100 and 200 mu M. Decreased rate of TEMPONE reduction and increased production of certain ROS species (peroxynitrite and hydrogen peroxide anion) indicates that free radical metabolism, thus redox status was changed, and antioxidant capacity damaged in the CONP treated 518A2 and HT-29 cells. In conclusion, changes in intracellular redox status induced by CONP are partly attributed to the prooxidant activity of the nanoparticles. Further, ROS induced cell damages might eventually lead to the cell death. However, low inhibitory potential of CONP in the other human cell lines tested indicates that CONP may be safe for human usage in industry and medicine. (C) 2015 Elsevier Ireland Ltd. All rights reserved.
T2  - Chemico-biological Interactions
T1  - Anti-cancer effects of cerium oxide nanoparticles and its intracellular redox activity
VL  - 232
SP  - 85
EP  - 93
DO  - 10.1016/j.cbi.2015.03.013
ER  - 
@article{
author = "Pešić, Milica and Podolski-Renić, Ana and Stojković, Sonja and Matović, Branko and Zmejkoski, Danica and Kojić, Vesna and Bogdanović, Gordana and Pavicevic, Aleksandra and Mojovic, Milos and Savić, Aleksandar and Milenković, Ivana and Kalauzi, Aleksandar and Radotić, Ksenija",
year = "2015",
abstract = "Data on medical applications of cerium oxide nanoparticles CeO2 (CONP) are promising, yet information regarding their action in cells is incomplete and there are conflicting reports about in vitro toxicity. Herein, we have studied cytotoxic effect of CONP in several cancer and normal cell lines and their potential to change intracellular redox status. The IC50 was achieved only in two of eight tested cell lines, melanoma 518A2 and colorectal adenocarcinoma HT-29. Self-propagating room temperature method was applied to produce CONP with an average crystalline size of 4 nm. The results confirmed presence of Ce3+ and O2- vacancies. The induction of cell death by CONP and the production of reactive oxygen species (ROS) were analyzed by flow-cytometry. Free radicals related antioxidant capacity of the cells was studied by the reduction of stable free radical TEMPONE using electron spin resonance spectroscopy. CONP showed low or moderate cytotoxicity in cancer cell lines: adenocarcinoma DLD1 and multi-drug resistant DLD1-TxR, non-small cell lung carcinoma NCI-H460 and multi-drug resistant NCI-H460/R, while normal cell lines (keratinocytes HaCaT, lung fetal fibroblasts MRC-5) were insensitive. The most sensitive were 518A2 melanoma and HT-29 colorectal adenocarcinoma cell lines, with the IC50 values being between 100 and 200 mu M. Decreased rate of TEMPONE reduction and increased production of certain ROS species (peroxynitrite and hydrogen peroxide anion) indicates that free radical metabolism, thus redox status was changed, and antioxidant capacity damaged in the CONP treated 518A2 and HT-29 cells. In conclusion, changes in intracellular redox status induced by CONP are partly attributed to the prooxidant activity of the nanoparticles. Further, ROS induced cell damages might eventually lead to the cell death. However, low inhibitory potential of CONP in the other human cell lines tested indicates that CONP may be safe for human usage in industry and medicine. (C) 2015 Elsevier Ireland Ltd. All rights reserved.",
journal = "Chemico-biological Interactions",
title = "Anti-cancer effects of cerium oxide nanoparticles and its intracellular redox activity",
volume = "232",
pages = "85-93",
doi = "10.1016/j.cbi.2015.03.013"
}
Pešić, M., Podolski-Renić, A., Stojković, S., Matović, B., Zmejkoski, D., Kojić, V., Bogdanović, G., Pavicevic, A., Mojovic, M., Savić, A., Milenković, I., Kalauzi, A.,& Radotić, K.. (2015). Anti-cancer effects of cerium oxide nanoparticles and its intracellular redox activity. in Chemico-biological Interactions, 232, 85-93.
https://doi.org/10.1016/j.cbi.2015.03.013
Pešić M, Podolski-Renić A, Stojković S, Matović B, Zmejkoski D, Kojić V, Bogdanović G, Pavicevic A, Mojovic M, Savić A, Milenković I, Kalauzi A, Radotić K. Anti-cancer effects of cerium oxide nanoparticles and its intracellular redox activity. in Chemico-biological Interactions. 2015;232:85-93.
doi:10.1016/j.cbi.2015.03.013 .
Pešić, Milica, Podolski-Renić, Ana, Stojković, Sonja, Matović, Branko, Zmejkoski, Danica, Kojić, Vesna, Bogdanović, Gordana, Pavicevic, Aleksandra, Mojovic, Milos, Savić, Aleksandar, Milenković, Ivana, Kalauzi, Aleksandar, Radotić, Ksenija, "Anti-cancer effects of cerium oxide nanoparticles and its intracellular redox activity" in Chemico-biological Interactions, 232 (2015):85-93,
https://doi.org/10.1016/j.cbi.2015.03.013 . .
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