TY  - JOUR
AU  - Janković, Drina
AU  - Vranješ-Đurić, Sanja
AU  - Đokić, Divna Đ.
AU  - Marković, Mirjana
AU  - Ajdinovic, Boris
AU  - Jaukovic, Ljiljana
AU  - Nikolić, Nadežda S.
PY  - 2012
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/4800
AB  - In this study, tin fluoride colloid (SnF-c) was prepared, labeled with yttrium-90 (90Y), and characterized with respect to its physicochemical properties and biological behavior in an animal model. Particle size of SnF-c, at constant concentration of SnF2, was dependent on pH, concentration of sodium fluoride (NaF), temperature, and time. The particle size of SnF-c decreased with an increase in NaF concentration and a decrease in reaction mixture pH. Radiolabeling yield of 90YSnF-c at higher temperature increased and it was greater than 98% for the preparation at 95 degrees C. The 90YSnF-c demonstrated high in vitro stability both in human serum and human synovial fluid at 37 degrees C up to 7 days. In vivo distribution studies in healthy male Wistar rats of 90YSnF-c (particles LT 1 mu m), following intravenous administration, revealed that the localization takes place preferably in the liver. The 90YSnF-c (particles GT 1 mu m) was well retained in the synovial space for 96 h after intra-articular injection, whereas leakage of 90Y from the joint was 1.96% over this period. Because of high labeling yield and stability, 90YSnF-c might be a promising agent for radiosynovectomy or therapy of liver malignancies. (C) 2012 Wiley Periodicals, Inc. and the American Pharmacists Association J Pharm Sci 101:21942203, 2012
T2  - Journal of Pharmaceutical Sciences
T1  - 90Y-labeled tin fluoride colloid as a promising therapeutic agent: Preparation, characterization, and biological study in rats
VL  - 101
IS  - 6
SP  - 2194
EP  - 2203
DO  - 10.1002/jps.23114
ER  - 

@article{
author = "Janković, Drina and Vranješ-Đurić, Sanja and Đokić, Divna Đ. and Marković, Mirjana and Ajdinovic, Boris and Jaukovic, Ljiljana and Nikolić, Nadežda S.",
year = "2012",
abstract = "In this study, tin fluoride colloid (SnF-c) was prepared, labeled with yttrium-90 (90Y), and characterized with respect to its physicochemical properties and biological behavior in an animal model. Particle size of SnF-c, at constant concentration of SnF2, was dependent on pH, concentration of sodium fluoride (NaF), temperature, and time. The particle size of SnF-c decreased with an increase in NaF concentration and a decrease in reaction mixture pH. Radiolabeling yield of 90YSnF-c at higher temperature increased and it was greater than 98% for the preparation at 95 degrees C. The 90YSnF-c demonstrated high in vitro stability both in human serum and human synovial fluid at 37 degrees C up to 7 days. In vivo distribution studies in healthy male Wistar rats of 90YSnF-c (particles LT 1 mu m), following intravenous administration, revealed that the localization takes place preferably in the liver. The 90YSnF-c (particles GT 1 mu m) was well retained in the synovial space for 96 h after intra-articular injection, whereas leakage of 90Y from the joint was 1.96% over this period. Because of high labeling yield and stability, 90YSnF-c might be a promising agent for radiosynovectomy or therapy of liver malignancies. (C) 2012 Wiley Periodicals, Inc. and the American Pharmacists Association J Pharm Sci 101:21942203, 2012",
journal = "Journal of Pharmaceutical Sciences",
title = "90Y-labeled tin fluoride colloid as a promising therapeutic agent: Preparation, characterization, and biological study in rats",
volume = "101",
number = "6",
pages = "2194-2203",
doi = "10.1002/jps.23114"
}

Janković, D., Vranješ-Đurić, S., Đokić, D. Đ., Marković, M., Ajdinovic, B., Jaukovic, L.,& Nikolić, N. S.. (2012). 90Y-labeled tin fluoride colloid as a promising therapeutic agent: Preparation, characterization, and biological study in rats. in Journal of Pharmaceutical Sciences, 101(6), 2194-2203.
https://doi.org/10.1002/jps.23114

Janković D, Vranješ-Đurić S, Đokić DĐ, Marković M, Ajdinovic B, Jaukovic L, Nikolić NS. 90Y-labeled tin fluoride colloid as a promising therapeutic agent: Preparation, characterization, and biological study in rats. in Journal of Pharmaceutical Sciences. 2012;101(6):2194-2203.
doi:10.1002/jps.23114 .

Janković, Drina, Vranješ-Đurić, Sanja, Đokić, Divna Đ., Marković, Mirjana, Ajdinovic, Boris, Jaukovic, Ljiljana, Nikolić, Nadežda S., "90Y-labeled tin fluoride colloid as a promising therapeutic agent: Preparation, characterization, and biological study in rats" in Journal of Pharmaceutical Sciences, 101, no. 6 (2012):2194-2203,
https://doi.org/10.1002/jps.23114 . .

TY  - JOUR
AU  - Petrović, Đorđe
AU  - Nikolić, Nadežda S.
AU  - Stanković, Dragana
AU  - Đokić, Divna Đ.
PY  - 2012
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/5069
AB  - Radiopharmaceuticals based on Y-90 are widely used in the treatment of malignant deseases. In order to meet the requirements for their future application, a Sr-90/Y-90 generator was developed and 90Y eluted from this locally produced generator was used for the radiolabelling of the DOTA-conjugated somatostatin analog [DOTA(0),Tyr(3)] octreotate and the preparation of [Y-90-DOTA(0),Tyr(3)] octreotate (Y-90-DOTATATE) for peptide receptore radionuclide therapy. Sr-90/Y-90 generator was based on the electrochemical separation of Y-90 from Sr-90 in a two-cycle electrolysis procedure. Three electrode cells were used to perform both electrolyses. In both cycles, working electrodes were kept on constant potential. The pH of the solution was adjusted to 2.7 of the value before the electrolyses. The radionucliclic purity of the Y-90 solution was analysed by ITLC and extraction paper chromatography. The labelling of peptide (100 mu g DOTATATE) with (YCl3)-Y-90 was performed at 95 degrees C for 30 minutes. Radiochemical purity was determined by HPLC and chromatographic separation, using a solid SepPak C-18 column. Results obtained confirmed the efficiency of our electrochemical separation technique and quality control methods for Y-90. The achieved efficiency of the Sr-90/Y-90 generator above 96% of the theoretical value represents a good basis for the further development of this generator. The labelling of the DOTATATE with Y-90 exhibited a high efficiency, too: there was less than 1% of Y-90(3+) in the Y-90-DOTATATE.
T2  - Nuclear technology and radiation protection
T1  - Electrochemical Separation of 90-Yttrium in the Electrochemical Sr-90/Y-90 Generator and Its Use for Radiolabelling of Dota-Conjugated Somatostatin Analog [Dota(0), Tyr(3)] Octreotate
VL  - 27
IS  - 3
SP  - 260
EP  - 268
DO  - 10.2298/NTRP1203260P
ER  - 

@article{
author = "Petrović, Đorđe and Nikolić, Nadežda S. and Stanković, Dragana and Đokić, Divna Đ.",
year = "2012",
abstract = "Radiopharmaceuticals based on Y-90 are widely used in the treatment of malignant deseases. In order to meet the requirements for their future application, a Sr-90/Y-90 generator was developed and 90Y eluted from this locally produced generator was used for the radiolabelling of the DOTA-conjugated somatostatin analog [DOTA(0),Tyr(3)] octreotate and the preparation of [Y-90-DOTA(0),Tyr(3)] octreotate (Y-90-DOTATATE) for peptide receptore radionuclide therapy. Sr-90/Y-90 generator was based on the electrochemical separation of Y-90 from Sr-90 in a two-cycle electrolysis procedure. Three electrode cells were used to perform both electrolyses. In both cycles, working electrodes were kept on constant potential. The pH of the solution was adjusted to 2.7 of the value before the electrolyses. The radionucliclic purity of the Y-90 solution was analysed by ITLC and extraction paper chromatography. The labelling of peptide (100 mu g DOTATATE) with (YCl3)-Y-90 was performed at 95 degrees C for 30 minutes. Radiochemical purity was determined by HPLC and chromatographic separation, using a solid SepPak C-18 column. Results obtained confirmed the efficiency of our electrochemical separation technique and quality control methods for Y-90. The achieved efficiency of the Sr-90/Y-90 generator above 96% of the theoretical value represents a good basis for the further development of this generator. The labelling of the DOTATATE with Y-90 exhibited a high efficiency, too: there was less than 1% of Y-90(3+) in the Y-90-DOTATATE.",
journal = "Nuclear technology and radiation protection",
title = "Electrochemical Separation of 90-Yttrium in the Electrochemical Sr-90/Y-90 Generator and Its Use for Radiolabelling of Dota-Conjugated Somatostatin Analog [Dota(0), Tyr(3)] Octreotate",
volume = "27",
number = "3",
pages = "260-268",
doi = "10.2298/NTRP1203260P"
}

Petrović, Đ., Nikolić, N. S., Stanković, D.,& Đokić, D. Đ.. (2012). Electrochemical Separation of 90-Yttrium in the Electrochemical Sr-90/Y-90 Generator and Its Use for Radiolabelling of Dota-Conjugated Somatostatin Analog [Dota(0), Tyr(3)] Octreotate. in Nuclear technology and radiation protection, 27(3), 260-268.
https://doi.org/10.2298/NTRP1203260P

Petrović Đ, Nikolić NS, Stanković D, Đokić DĐ. Electrochemical Separation of 90-Yttrium in the Electrochemical Sr-90/Y-90 Generator and Its Use for Radiolabelling of Dota-Conjugated Somatostatin Analog [Dota(0), Tyr(3)] Octreotate. in Nuclear technology and radiation protection. 2012;27(3):260-268.
doi:10.2298/NTRP1203260P .

Petrović, Đorđe, Nikolić, Nadežda S., Stanković, Dragana, Đokić, Divna Đ., "Electrochemical Separation of 90-Yttrium in the Electrochemical Sr-90/Y-90 Generator and Its Use for Radiolabelling of Dota-Conjugated Somatostatin Analog [Dota(0), Tyr(3)] Octreotate" in Nuclear technology and radiation protection, 27, no. 3 (2012):260-268,
https://doi.org/10.2298/NTRP1203260P . .

TY  - JOUR
AU  - Tsotakos, T.
AU  - Tsoukalas, C.
AU  - Patsis, G.
AU  - Panagiotopoulou, A.
AU  - Nikolić, Nadežda S.
AU  - Janković, Drina
AU  - Đokić, Divna Đ.
AU  - Raptopoulou, C. P.
AU  - Terzis, A.
AU  - Papagiannopoulou, D.
AU  - Pelecanou, M.
AU  - Papadopoulos, M.
AU  - Pirmettis, Ioannis
PY  - 2011
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/4546
AB  - Two rhenium(I) tricarbonyl complexes with the tridentate monoanionic NSO ligands, 4-(benzimidazol-2-yl)-3-thiabutanoic acid (complex 3) and [1-(11-carboxyundecanyl)-4-(benzimidazol-2-yl)]-3-thiabutanoic acid (complex 4) were synthesized and characterized by spectroscopic methods and elemental analysis. X-ray crystallographic analysis of complex 3 revealed a distorted octahedral geometry around rhenium defined by the three facially bound CO groups and the NSO donor atom set of the tridentate ligand. The analogous technetium-99m complexes (complexes 5 and 6) were also prepared quantitatively by reaction of the NSO ligands with the fac-[Tc-99m(H2O)(3)(CO)(3)](+) synthon and their identity was established by chromatographic comparison to their rhenium congeners. Biodistribution in mice of complex 6 bearing the fatty acid chain showed significant heart uptake (6.26 +/- 0.79% ID/g p.i.) at 1 min accompanied, however, with a heart: blood ratio below 1. (C) 2011 Elsevier B. V. All rights reserved.
T2  - Inorganica Chimica Acta
T1  - Benzimidazole derivatives as NSO ligands for the fac-[M(CO)(3)](+) (M = Re, Tc-99m)
VL  - 377
IS  - 1
SP  - 62
EP  - 68
DO  - 10.1016/j.ica.2011.07.035
ER  - 

@article{
author = "Tsotakos, T. and Tsoukalas, C. and Patsis, G. and Panagiotopoulou, A. and Nikolić, Nadežda S. and Janković, Drina and Đokić, Divna Đ. and Raptopoulou, C. P. and Terzis, A. and Papagiannopoulou, D. and Pelecanou, M. and Papadopoulos, M. and Pirmettis, Ioannis",
year = "2011",
abstract = "Two rhenium(I) tricarbonyl complexes with the tridentate monoanionic NSO ligands, 4-(benzimidazol-2-yl)-3-thiabutanoic acid (complex 3) and [1-(11-carboxyundecanyl)-4-(benzimidazol-2-yl)]-3-thiabutanoic acid (complex 4) were synthesized and characterized by spectroscopic methods and elemental analysis. X-ray crystallographic analysis of complex 3 revealed a distorted octahedral geometry around rhenium defined by the three facially bound CO groups and the NSO donor atom set of the tridentate ligand. The analogous technetium-99m complexes (complexes 5 and 6) were also prepared quantitatively by reaction of the NSO ligands with the fac-[Tc-99m(H2O)(3)(CO)(3)](+) synthon and their identity was established by chromatographic comparison to their rhenium congeners. Biodistribution in mice of complex 6 bearing the fatty acid chain showed significant heart uptake (6.26 +/- 0.79% ID/g p.i.) at 1 min accompanied, however, with a heart: blood ratio below 1. (C) 2011 Elsevier B. V. All rights reserved.",
journal = "Inorganica Chimica Acta",
title = "Benzimidazole derivatives as NSO ligands for the fac-[M(CO)(3)](+) (M = Re, Tc-99m)",
volume = "377",
number = "1",
pages = "62-68",
doi = "10.1016/j.ica.2011.07.035"
}

Tsotakos, T., Tsoukalas, C., Patsis, G., Panagiotopoulou, A., Nikolić, N. S., Janković, D., Đokić, D. Đ., Raptopoulou, C. P., Terzis, A., Papagiannopoulou, D., Pelecanou, M., Papadopoulos, M.,& Pirmettis, I.. (2011). Benzimidazole derivatives as NSO ligands for the fac-[M(CO)(3)](+) (M = Re, Tc-99m). in Inorganica Chimica Acta, 377(1), 62-68.
https://doi.org/10.1016/j.ica.2011.07.035

Tsotakos T, Tsoukalas C, Patsis G, Panagiotopoulou A, Nikolić NS, Janković D, Đokić DĐ, Raptopoulou CP, Terzis A, Papagiannopoulou D, Pelecanou M, Papadopoulos M, Pirmettis I. Benzimidazole derivatives as NSO ligands for the fac-[M(CO)(3)](+) (M = Re, Tc-99m). in Inorganica Chimica Acta. 2011;377(1):62-68.
doi:10.1016/j.ica.2011.07.035 .

Tsotakos, T., Tsoukalas, C., Patsis, G., Panagiotopoulou, A., Nikolić, Nadežda S., Janković, Drina, Đokić, Divna Đ., Raptopoulou, C. P., Terzis, A., Papagiannopoulou, D., Pelecanou, M., Papadopoulos, M., Pirmettis, Ioannis, "Benzimidazole derivatives as NSO ligands for the fac-[M(CO)(3)](+) (M = Re, Tc-99m)" in Inorganica Chimica Acta, 377, no. 1 (2011):62-68,
https://doi.org/10.1016/j.ica.2011.07.035 . .

TY  - CONF
AU  - Petrović, Đorđe
AU  - Đokić, Divna Đ.
AU  - Dobrijević, R.
AU  - Stanković, Dragana
AU  - Glodić, Pavle
PY  - 2010
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9298
AB  - Using of radiopharmaceuticals based on 90Y in the treatment of solid cancer is
increasing in recent years. Therefore, generators have been developed for obtaining
the 90Y using a feature of 90Sr for spontaneous breakthrough and its equilibrium
with 90Y. Electrochemical separation of 90Y from 90Sr has become the basic method
for obtaining 90Y in high radiochemical yield. For the preliminary study, we used
the electrochemical system with two electrochemical cells. Quality control was
performed using extraction paper chromatography (EPC). Preliminary results
showed that the separation completed successfully in both ways, quantity and
quality.
PB  - Society of Physical Chemists of Serbia
C3  - Physical chemistry 2010 : 10th international conference on fundamental and applied aspects of physical chemistry
T1  - Development of 90Sr/90Y generator using electrochemical separation
UR  - https://hdl.handle.net/21.15107/rcub_vinar_9298
ER  - 

@conference{
author = "Petrović, Đorđe and Đokić, Divna Đ. and Dobrijević, R. and Stanković, Dragana and Glodić, Pavle",
year = "2010",
abstract = "Using of radiopharmaceuticals based on 90Y in the treatment of solid cancer is
increasing in recent years. Therefore, generators have been developed for obtaining
the 90Y using a feature of 90Sr for spontaneous breakthrough and its equilibrium
with 90Y. Electrochemical separation of 90Y from 90Sr has become the basic method
for obtaining 90Y in high radiochemical yield. For the preliminary study, we used
the electrochemical system with two electrochemical cells. Quality control was
performed using extraction paper chromatography (EPC). Preliminary results
showed that the separation completed successfully in both ways, quantity and
quality.",
publisher = "Society of Physical Chemists of Serbia",
journal = "Physical chemistry 2010 : 10th international conference on fundamental and applied aspects of physical chemistry",
title = "Development of 90Sr/90Y generator using electrochemical separation",
url = "https://hdl.handle.net/21.15107/rcub_vinar_9298"
}

Petrović, Đ., Đokić, D. Đ., Dobrijević, R., Stanković, D.,& Glodić, P.. (2010). Development of 90Sr/90Y generator using electrochemical separation. in Physical chemistry 2010 : 10th international conference on fundamental and applied aspects of physical chemistry
Society of Physical Chemists of Serbia..
https://hdl.handle.net/21.15107/rcub_vinar_9298

Petrović Đ, Đokić DĐ, Dobrijević R, Stanković D, Glodić P. Development of 90Sr/90Y generator using electrochemical separation. in Physical chemistry 2010 : 10th international conference on fundamental and applied aspects of physical chemistry. 2010;.
https://hdl.handle.net/21.15107/rcub_vinar_9298 .

Petrović, Đorđe, Đokić, Divna Đ., Dobrijević, R., Stanković, Dragana, Glodić, Pavle, "Development of 90Sr/90Y generator using electrochemical separation" in Physical chemistry 2010 : 10th international conference on fundamental and applied aspects of physical chemistry (2010),
https://hdl.handle.net/21.15107/rcub_vinar_9298 .

TY  - CONF
AU  - Nikolic, N. S.
AU  - Vranješ-Đurić, Sanja
AU  - Janković, Drina
AU  - Đokić, Divna Đ.
PY  - 2010
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/6888
C3  - European Journal of Nuclear Medicine and Molecular Imaging
T1  - Influence of phosphonate-hydroxyapatite microparticle interaction on the delivery of radiation and drugs
VL  - 37
SP  - S360
EP  - S360
UR  - https://hdl.handle.net/21.15107/rcub_vinar_6888
ER  - 

@conference{
author = "Nikolic, N. S. and Vranješ-Đurić, Sanja and Janković, Drina and Đokić, Divna Đ.",
year = "2010",
journal = "European Journal of Nuclear Medicine and Molecular Imaging",
title = "Influence of phosphonate-hydroxyapatite microparticle interaction on the delivery of radiation and drugs",
volume = "37",
pages = "S360-S360",
url = "https://hdl.handle.net/21.15107/rcub_vinar_6888"
}

Nikolic, N. S., Vranješ-Đurić, S., Janković, D.,& Đokić, D. Đ.. (2010). Influence of phosphonate-hydroxyapatite microparticle interaction on the delivery of radiation and drugs. in European Journal of Nuclear Medicine and Molecular Imaging, 37, S360-S360.
https://hdl.handle.net/21.15107/rcub_vinar_6888

Nikolic NS, Vranješ-Đurić S, Janković D, Đokić DĐ. Influence of phosphonate-hydroxyapatite microparticle interaction on the delivery of radiation and drugs. in European Journal of Nuclear Medicine and Molecular Imaging. 2010;37:S360-S360.
https://hdl.handle.net/21.15107/rcub_vinar_6888 .

Nikolic, N. S., Vranješ-Đurić, Sanja, Janković, Drina, Đokić, Divna Đ., "Influence of phosphonate-hydroxyapatite microparticle interaction on the delivery of radiation and drugs" in European Journal of Nuclear Medicine and Molecular Imaging, 37 (2010):S360-S360,
https://hdl.handle.net/21.15107/rcub_vinar_6888 .

TY  - CONF
AU  - Đokić, Divna Đ.
AU  - Janković, Drina
AU  - Vranješ-Đurić, Sanja
AU  - Nikolić, Nadežda S.
PY  - 2010
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/4083
C3  - Nuclear Medicine and Biology
T1  - Analysis of the yttrium-90-labelled human serum albumin microspheres
VL  - 37
IS  - 6
SP  - 696
EP  - 696
DO  - 10.1016/j.nucmedbio.2010.04.184
ER  - 

@conference{
author = "Đokić, Divna Đ. and Janković, Drina and Vranješ-Đurić, Sanja and Nikolić, Nadežda S.",
year = "2010",
journal = "Nuclear Medicine and Biology",
title = "Analysis of the yttrium-90-labelled human serum albumin microspheres",
volume = "37",
number = "6",
pages = "696-696",
doi = "10.1016/j.nucmedbio.2010.04.184"
}

Đokić, D. Đ., Janković, D., Vranješ-Đurić, S.,& Nikolić, N. S.. (2010). Analysis of the yttrium-90-labelled human serum albumin microspheres. in Nuclear Medicine and Biology, 37(6), 696-696.
https://doi.org/10.1016/j.nucmedbio.2010.04.184

Đokić DĐ, Janković D, Vranješ-Đurić S, Nikolić NS. Analysis of the yttrium-90-labelled human serum albumin microspheres. in Nuclear Medicine and Biology. 2010;37(6):696-696.
doi:10.1016/j.nucmedbio.2010.04.184 .

Đokić, Divna Đ., Janković, Drina, Vranješ-Đurić, Sanja, Nikolić, Nadežda S., "Analysis of the yttrium-90-labelled human serum albumin microspheres" in Nuclear Medicine and Biology, 37, no. 6 (2010):696-696,
https://doi.org/10.1016/j.nucmedbio.2010.04.184 . .

TY  - JOUR
AU  - Kyprianidou, P.
AU  - Tsoukalas, C.
AU  - Patsis, G.
AU  - Papagiannopoulou, D.
AU  - Nikolić, Nadežda S.
AU  - Janković, Drina
AU  - Đokić, Divna Đ.
AU  - Raptopoulou, C. P.
AU  - Pelecanou, M.
AU  - Papadopoulos, M.
AU  - Pirmettis, Ioannis
PY  - 2009
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3811
AB  - Two rhenium(l) tricarbonyl complexes, with the monoanionic tridentate NSO type ligand, 4-(imidazolin-2-yl)-3-thiabutanoic acid and 4-(N-ethylimidazolin-2-yl)-3-thiabutanoic acid were synthesized and isolated in pure form. Both complexes were characterized by spectroscopic methods and elemental analysis. The solid-state structure of 4-(imidazolin-2-yl)-3-thiabutanoic acid and of both complexes was established by X-ray crystallography. The geometry about the rhenium is octahedral. The analogous technetium-99m complexes were also prepared quantitatively by the reaction of both ligands with the fac-[(99m)Tc(CO)(3)(H(2)O)(3)](+) synthon and their identity was established by chromatographic comparison to their rhenium congeners. (C) 2009 Elsevier Ltd. All rights reserved.
T2  - Polyhedron
T1  - Rhenium(I) and technetium-99m(I) fac-tricarbonyl complexes with 4-(imidazolin-2-yl)-3-thiabutanoic acid derivatives as tridentate ligands: Synthesis and structural characterization
VL  - 28
IS  - 15
SP  - 3171
EP  - 3176
DO  - 10.1016/j.poly.2009.04.005
ER  - 

@article{
author = "Kyprianidou, P. and Tsoukalas, C. and Patsis, G. and Papagiannopoulou, D. and Nikolić, Nadežda S. and Janković, Drina and Đokić, Divna Đ. and Raptopoulou, C. P. and Pelecanou, M. and Papadopoulos, M. and Pirmettis, Ioannis",
year = "2009",
abstract = "Two rhenium(l) tricarbonyl complexes, with the monoanionic tridentate NSO type ligand, 4-(imidazolin-2-yl)-3-thiabutanoic acid and 4-(N-ethylimidazolin-2-yl)-3-thiabutanoic acid were synthesized and isolated in pure form. Both complexes were characterized by spectroscopic methods and elemental analysis. The solid-state structure of 4-(imidazolin-2-yl)-3-thiabutanoic acid and of both complexes was established by X-ray crystallography. The geometry about the rhenium is octahedral. The analogous technetium-99m complexes were also prepared quantitatively by the reaction of both ligands with the fac-[(99m)Tc(CO)(3)(H(2)O)(3)](+) synthon and their identity was established by chromatographic comparison to their rhenium congeners. (C) 2009 Elsevier Ltd. All rights reserved.",
journal = "Polyhedron",
title = "Rhenium(I) and technetium-99m(I) fac-tricarbonyl complexes with 4-(imidazolin-2-yl)-3-thiabutanoic acid derivatives as tridentate ligands: Synthesis and structural characterization",
volume = "28",
number = "15",
pages = "3171-3176",
doi = "10.1016/j.poly.2009.04.005"
}

Kyprianidou, P., Tsoukalas, C., Patsis, G., Papagiannopoulou, D., Nikolić, N. S., Janković, D., Đokić, D. Đ., Raptopoulou, C. P., Pelecanou, M., Papadopoulos, M.,& Pirmettis, I.. (2009). Rhenium(I) and technetium-99m(I) fac-tricarbonyl complexes with 4-(imidazolin-2-yl)-3-thiabutanoic acid derivatives as tridentate ligands: Synthesis and structural characterization. in Polyhedron, 28(15), 3171-3176.
https://doi.org/10.1016/j.poly.2009.04.005

Kyprianidou P, Tsoukalas C, Patsis G, Papagiannopoulou D, Nikolić NS, Janković D, Đokić DĐ, Raptopoulou CP, Pelecanou M, Papadopoulos M, Pirmettis I. Rhenium(I) and technetium-99m(I) fac-tricarbonyl complexes with 4-(imidazolin-2-yl)-3-thiabutanoic acid derivatives as tridentate ligands: Synthesis and structural characterization. in Polyhedron. 2009;28(15):3171-3176.
doi:10.1016/j.poly.2009.04.005 .

Kyprianidou, P., Tsoukalas, C., Patsis, G., Papagiannopoulou, D., Nikolić, Nadežda S., Janković, Drina, Đokić, Divna Đ., Raptopoulou, C. P., Pelecanou, M., Papadopoulos, M., Pirmettis, Ioannis, "Rhenium(I) and technetium-99m(I) fac-tricarbonyl complexes with 4-(imidazolin-2-yl)-3-thiabutanoic acid derivatives as tridentate ligands: Synthesis and structural characterization" in Polyhedron, 28, no. 15 (2009):3171-3176,
https://doi.org/10.1016/j.poly.2009.04.005 . .

TY  - JOUR
AU  - Đokić, Divna Đ.
AU  - Janković, Drina
AU  - Nikolić, Nadežda S.
PY  - 2009
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3645
AB  - Introduction: The aim of this study was to find out if Y-90 could form a stabile complex with meso-2,3-dimercaptosuccinic acid (DMSA) and if Y-90-DMSA may have potential for tumor therapy in the palliative treatment of bone metastases. Methods: The preparing of Y-90-DMSA was carried out by varying experimental parameters, such as ligand concentration, pH, time, and temperature of the reaction, in order to maximize the labeling yield. Analysis of the complexes enclosed the radiochemical quality control (instant thin-layer chromatography, paper chromatography, and high-performance liquid chromatography), determination of pharmacokinetical parameters as well as biodistrbution study in health male Wistar rats. In vitro stability of the complexes was tested too. Results: Y-90-DMSA could be prepared in high yields ( GT 95%) under optimized conditions of reaction. Stability studies in saline and human serum in vitro showed no significant release of activity from the ligand over 24 hours and 10 days, respectively. The preliminary biodistribution results in rat at 2 hours indicated that Y-90-DMSA, at both pH levels, was significantly retained into bone. The uptake in the kidneys was lower for Y-90-DMSA at pH 8.0 then at pH 3.0. The retention in other organs was negligible. Conclusions: Y-90 complexes could be made with ease with DMSA. Y-90-DMSA was obtained in good yield and was found to be very stable. A promising biodistribution result of this complex pointed at potential in the palliative treatment of bone metastases.
T2  - Cancer Biotherapy and Radiopharmaceuticals
T1  - Preparation and In Vivo Evaluation of Y-90-Meso-Dimercaptosuccinic Acid (Y-90-DMSA) for Possible Therapeutic Use: Comparison with Tc-99m-DMSA
VL  - 24
IS  - 1
SP  - 129
EP  - 136
DO  - 10.1089/cbr.2008.0499
ER  - 

@article{
author = "Đokić, Divna Đ. and Janković, Drina and Nikolić, Nadežda S.",
year = "2009",
abstract = "Introduction: The aim of this study was to find out if Y-90 could form a stabile complex with meso-2,3-dimercaptosuccinic acid (DMSA) and if Y-90-DMSA may have potential for tumor therapy in the palliative treatment of bone metastases. Methods: The preparing of Y-90-DMSA was carried out by varying experimental parameters, such as ligand concentration, pH, time, and temperature of the reaction, in order to maximize the labeling yield. Analysis of the complexes enclosed the radiochemical quality control (instant thin-layer chromatography, paper chromatography, and high-performance liquid chromatography), determination of pharmacokinetical parameters as well as biodistrbution study in health male Wistar rats. In vitro stability of the complexes was tested too. Results: Y-90-DMSA could be prepared in high yields ( GT 95%) under optimized conditions of reaction. Stability studies in saline and human serum in vitro showed no significant release of activity from the ligand over 24 hours and 10 days, respectively. The preliminary biodistribution results in rat at 2 hours indicated that Y-90-DMSA, at both pH levels, was significantly retained into bone. The uptake in the kidneys was lower for Y-90-DMSA at pH 8.0 then at pH 3.0. The retention in other organs was negligible. Conclusions: Y-90 complexes could be made with ease with DMSA. Y-90-DMSA was obtained in good yield and was found to be very stable. A promising biodistribution result of this complex pointed at potential in the palliative treatment of bone metastases.",
journal = "Cancer Biotherapy and Radiopharmaceuticals",
title = "Preparation and In Vivo Evaluation of Y-90-Meso-Dimercaptosuccinic Acid (Y-90-DMSA) for Possible Therapeutic Use: Comparison with Tc-99m-DMSA",
volume = "24",
number = "1",
pages = "129-136",
doi = "10.1089/cbr.2008.0499"
}

Đokić, D. Đ., Janković, D.,& Nikolić, N. S.. (2009). Preparation and In Vivo Evaluation of Y-90-Meso-Dimercaptosuccinic Acid (Y-90-DMSA) for Possible Therapeutic Use: Comparison with Tc-99m-DMSA. in Cancer Biotherapy and Radiopharmaceuticals, 24(1), 129-136.
https://doi.org/10.1089/cbr.2008.0499

Đokić DĐ, Janković D, Nikolić NS. Preparation and In Vivo Evaluation of Y-90-Meso-Dimercaptosuccinic Acid (Y-90-DMSA) for Possible Therapeutic Use: Comparison with Tc-99m-DMSA. in Cancer Biotherapy and Radiopharmaceuticals. 2009;24(1):129-136.
doi:10.1089/cbr.2008.0499 .

Đokić, Divna Đ., Janković, Drina, Nikolić, Nadežda S., "Preparation and In Vivo Evaluation of Y-90-Meso-Dimercaptosuccinic Acid (Y-90-DMSA) for Possible Therapeutic Use: Comparison with Tc-99m-DMSA" in Cancer Biotherapy and Radiopharmaceuticals, 24, no. 1 (2009):129-136,
https://doi.org/10.1089/cbr.2008.0499 . .

TY  - JOUR
AU  - Jaksic, Emilija
AU  - Artiko, Vera
AU  - Beatovic, Slobodanka
AU  - Đokić, Divna Đ.
AU  - Janković, Drina
AU  - Saranovic, Dragana Sobic
AU  - Han, Ruben
AU  - Obradović, Vladimir
PY  - 2009
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3605
AB  - Objective Tc-99m-p-aminohippuric acid (PAH) is a new radiopharmaceutical rapidly secreted by the kidneys in a manner consistent with tubular secretion. A comparative study of renal scintigraphy and clearance with Tc-99m-PAH, diethylene triamine pentaacetic acid (DTPA) and mercaptoacetyltriglycine (MAG(3)) was performed. Methods (TC)-T-99m-PAH was prepared from a lyophilized kit by addition of sodium pertechnetate in the presence of DTPA. Ten healthy individuals were injected with 110 MBq of Tc-99m-PAH. A dynamic study was repeated with Tc-99m-DTPA and Tc-99m-MAG(3) several days later, after a 1-day interval. Clearance measurements were performed in five individuals. Results The mean values of time-to-peak activity (T-max) and the time from peak to 50% of peak activity (T-1/2) for Tc-99m-PAH (3.6 +/- 0.9 and 6.9 +/- 2.7 min, respectively) and Tc-99m-MAG, (3.5 +/- 0.8 and 6.8 +/- 2.1 respectively) were significantly lower in comparison with those of Tc-99m-DTPA (4.9 +/- 1.7 and 11.7 +/- 1.9 min, respectively). The mean value of Tc-99m-PAH clearance (186.9 +/- 12.2 ml/min) was significantly lower in comparison with MAG(3) clearance (303.9 +/- 19.5 ml/min) and significantly higher than DTPA clearance (85.0 +/- 24.1 ml/min). Conclusion Our preliminary results indicate the potential usefulness of Tc-99m-PAH for routine renal scintigraphy. Owing to its fast kinetics, excretion and high-quality images, it could be a suitable for Tc-99m-DTPA. Tc-99m-PAH clearance values, however, were significantly lower than those of MAG(3), and could not be used for the estimation of renal plasma flow. Nucl Med Commun 30:76-81 (C) 2009 Wolters Kluwer Health vertical bar Lippincott Williams and Wilkins.
T2  - Nuclear Medicine Communications
T1  - Clinical investigations of Tc-99m-p-aminohippuric acid as a new renal agent
VL  - 30
IS  - 1
SP  - 76
EP  - 81
DO  - 10.1097/MNM.0b013e328314b8bc
ER  - 

@article{
author = "Jaksic, Emilija and Artiko, Vera and Beatovic, Slobodanka and Đokić, Divna Đ. and Janković, Drina and Saranovic, Dragana Sobic and Han, Ruben and Obradović, Vladimir",
year = "2009",
abstract = "Objective Tc-99m-p-aminohippuric acid (PAH) is a new radiopharmaceutical rapidly secreted by the kidneys in a manner consistent with tubular secretion. A comparative study of renal scintigraphy and clearance with Tc-99m-PAH, diethylene triamine pentaacetic acid (DTPA) and mercaptoacetyltriglycine (MAG(3)) was performed. Methods (TC)-T-99m-PAH was prepared from a lyophilized kit by addition of sodium pertechnetate in the presence of DTPA. Ten healthy individuals were injected with 110 MBq of Tc-99m-PAH. A dynamic study was repeated with Tc-99m-DTPA and Tc-99m-MAG(3) several days later, after a 1-day interval. Clearance measurements were performed in five individuals. Results The mean values of time-to-peak activity (T-max) and the time from peak to 50% of peak activity (T-1/2) for Tc-99m-PAH (3.6 +/- 0.9 and 6.9 +/- 2.7 min, respectively) and Tc-99m-MAG, (3.5 +/- 0.8 and 6.8 +/- 2.1 respectively) were significantly lower in comparison with those of Tc-99m-DTPA (4.9 +/- 1.7 and 11.7 +/- 1.9 min, respectively). The mean value of Tc-99m-PAH clearance (186.9 +/- 12.2 ml/min) was significantly lower in comparison with MAG(3) clearance (303.9 +/- 19.5 ml/min) and significantly higher than DTPA clearance (85.0 +/- 24.1 ml/min). Conclusion Our preliminary results indicate the potential usefulness of Tc-99m-PAH for routine renal scintigraphy. Owing to its fast kinetics, excretion and high-quality images, it could be a suitable for Tc-99m-DTPA. Tc-99m-PAH clearance values, however, were significantly lower than those of MAG(3), and could not be used for the estimation of renal plasma flow. Nucl Med Commun 30:76-81 (C) 2009 Wolters Kluwer Health vertical bar Lippincott Williams and Wilkins.",
journal = "Nuclear Medicine Communications",
title = "Clinical investigations of Tc-99m-p-aminohippuric acid as a new renal agent",
volume = "30",
number = "1",
pages = "76-81",
doi = "10.1097/MNM.0b013e328314b8bc"
}

Jaksic, E., Artiko, V., Beatovic, S., Đokić, D. Đ., Janković, D., Saranovic, D. S., Han, R.,& Obradović, V.. (2009). Clinical investigations of Tc-99m-p-aminohippuric acid as a new renal agent. in Nuclear Medicine Communications, 30(1), 76-81.
https://doi.org/10.1097/MNM.0b013e328314b8bc

Jaksic E, Artiko V, Beatovic S, Đokić DĐ, Janković D, Saranovic DS, Han R, Obradović V. Clinical investigations of Tc-99m-p-aminohippuric acid as a new renal agent. in Nuclear Medicine Communications. 2009;30(1):76-81.
doi:10.1097/MNM.0b013e328314b8bc .

Jaksic, Emilija, Artiko, Vera, Beatovic, Slobodanka, Đokić, Divna Đ., Janković, Drina, Saranovic, Dragana Sobic, Han, Ruben, Obradović, Vladimir, "Clinical investigations of Tc-99m-p-aminohippuric acid as a new renal agent" in Nuclear Medicine Communications, 30, no. 1 (2009):76-81,
https://doi.org/10.1097/MNM.0b013e328314b8bc . .

TY  - CONF
AU  - Jaksic, E.
AU  - Beatovic, S.
AU  - Artiko, V.
AU  - Saranovic, D. Sobic
AU  - Pavlović, Suncan
AU  - Đokić, Divna Đ.
AU  - Janković, Drina
AU  - Obradović, V.
PY  - 2009
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2733
C3  - European Journal of Nuclear Medicine and Molecular Imaging
T1  - Comparison between Tc-99m p-Aminohippuric acid and Tc-99m MAG3 renography
VL  - 36
SP  - S437
EP  - S437
UR  - https://hdl.handle.net/21.15107/rcub_vinar_2733
ER  - 

@conference{
author = "Jaksic, E. and Beatovic, S. and Artiko, V. and Saranovic, D. Sobic and Pavlović, Suncan and Đokić, Divna Đ. and Janković, Drina and Obradović, V.",
year = "2009",
journal = "European Journal of Nuclear Medicine and Molecular Imaging",
title = "Comparison between Tc-99m p-Aminohippuric acid and Tc-99m MAG3 renography",
volume = "36",
pages = "S437-S437",
url = "https://hdl.handle.net/21.15107/rcub_vinar_2733"
}

Jaksic, E., Beatovic, S., Artiko, V., Saranovic, D. S., Pavlović, S., Đokić, D. Đ., Janković, D.,& Obradović, V.. (2009). Comparison between Tc-99m p-Aminohippuric acid and Tc-99m MAG3 renography. in European Journal of Nuclear Medicine and Molecular Imaging, 36, S437-S437.
https://hdl.handle.net/21.15107/rcub_vinar_2733

Jaksic E, Beatovic S, Artiko V, Saranovic DS, Pavlović S, Đokić DĐ, Janković D, Obradović V. Comparison between Tc-99m p-Aminohippuric acid and Tc-99m MAG3 renography. in European Journal of Nuclear Medicine and Molecular Imaging. 2009;36:S437-S437.
https://hdl.handle.net/21.15107/rcub_vinar_2733 .

Jaksic, E., Beatovic, S., Artiko, V., Saranovic, D. Sobic, Pavlović, Suncan, Đokić, Divna Đ., Janković, Drina, Obradović, V., "Comparison between Tc-99m p-Aminohippuric acid and Tc-99m MAG3 renography" in European Journal of Nuclear Medicine and Molecular Imaging, 36 (2009):S437-S437,
https://hdl.handle.net/21.15107/rcub_vinar_2733 .

TY  - CONF
AU  - Janković, Drina
AU  - Đokić, Divna Đ.
AU  - Nikolić, N.
PY  - 2008
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9384
AB  - In radionuclide therapy, the importance of 90Y as a beta-emitting radionuclide is increasing rapidly. The properties of the 90Y-labeled antimony trisulfide colloid (Sb2S3) were compared with the 99mTc-labeled one. Labeling efficiencies reached >96% and >97% for 90Y- and 99mTc-labeled colloids respectively. Both preparations were stable for 72 h in saline and 1% albumin solution. Filtration analysis showed that more than 94% of total 90Y radioactivity is associated with the colloidal particles smaller than 20 nm, while more than 90% of 99mTc radioactivity is associated with the particles retained on the filter with a 20 nm pore size. 90Y-labeled colloids showed high labeling efficiency, stability and potency for clinical use.
PB  - Society of Physical Chemists of Serbia
C3  - Physical chemistry 2008 : 9th international conference on fundamental and applied aspects of physical chemistry
T1  - Physico-chemical characterization of 90Y-labeled antimony trisulfide colloid and comparison with 99mTc-labeled one
VL  - 2
SP  - 462
EP  - 464
UR  - https://hdl.handle.net/21.15107/rcub_vinar_9384
ER  - 

@conference{
author = "Janković, Drina and Đokić, Divna Đ. and Nikolić, N.",
year = "2008",
abstract = "In radionuclide therapy, the importance of 90Y as a beta-emitting radionuclide is increasing rapidly. The properties of the 90Y-labeled antimony trisulfide colloid (Sb2S3) were compared with the 99mTc-labeled one. Labeling efficiencies reached >96% and >97% for 90Y- and 99mTc-labeled colloids respectively. Both preparations were stable for 72 h in saline and 1% albumin solution. Filtration analysis showed that more than 94% of total 90Y radioactivity is associated with the colloidal particles smaller than 20 nm, while more than 90% of 99mTc radioactivity is associated with the particles retained on the filter with a 20 nm pore size. 90Y-labeled colloids showed high labeling efficiency, stability and potency for clinical use.",
publisher = "Society of Physical Chemists of Serbia",
journal = "Physical chemistry 2008 : 9th international conference on fundamental and applied aspects of physical chemistry",
title = "Physico-chemical characterization of 90Y-labeled antimony trisulfide colloid and comparison with 99mTc-labeled one",
volume = "2",
pages = "462-464",
url = "https://hdl.handle.net/21.15107/rcub_vinar_9384"
}

Janković, D., Đokić, D. Đ.,& Nikolić, N.. (2008). Physico-chemical characterization of 90Y-labeled antimony trisulfide colloid and comparison with 99mTc-labeled one. in Physical chemistry 2008 : 9th international conference on fundamental and applied aspects of physical chemistry
Society of Physical Chemists of Serbia., 2, 462-464.
https://hdl.handle.net/21.15107/rcub_vinar_9384

Janković D, Đokić DĐ, Nikolić N. Physico-chemical characterization of 90Y-labeled antimony trisulfide colloid and comparison with 99mTc-labeled one. in Physical chemistry 2008 : 9th international conference on fundamental and applied aspects of physical chemistry. 2008;2:462-464.
https://hdl.handle.net/21.15107/rcub_vinar_9384 .

Janković, Drina, Đokić, Divna Đ., Nikolić, N., "Physico-chemical characterization of 90Y-labeled antimony trisulfide colloid and comparison with 99mTc-labeled one" in Physical chemistry 2008 : 9th international conference on fundamental and applied aspects of physical chemistry, 2 (2008):462-464,
https://hdl.handle.net/21.15107/rcub_vinar_9384 .

TY  - JOUR
AU  - Đokić, Divna Đ.
AU  - Janković, Drina
AU  - Nikolić, Nadežda S.
PY  - 2008
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3240
AB  - The goal of this investigation was to examine the possibilities for yttrium-90-labeling of the 2,3-dicarboxypropane-1,1-diphosphonic acid (DPD), which is currently labeled with technetium-99m and as a Tc-99m-DPD clinically used as bone imaging agent. Analysis of the complex enclosed the radiochemical quality control methods, biodistribution studies, as well as the determination of pharmacokinetic parameters. The biological behavior of complexes Y-90-DPD, Tc-99m-DPD and Y-90-labeled DPD-kit formulation [Y-90-(Sn)-DPD] in animal model was compared. The labeling conditions were standardized to give the maximum yield, which ranged between 93% and 98%. The examined Y-90 complex could be easily prepared, with an outstanding yield and was also found to be very stable for at least 10 h after Y-90-labeling. Protein binding value was 4.6 +/- 0.7% for Y-90-DPD complex and the complex possess a hydrophilic character. The satisfactory results of Y-90- DPD biodistribution in healthy test animals were obtained; the uptake in the bone was 11-13% ID/g after 24 h depending on the pH value during the preparation. With high skeletal uptake, a minimum uptake in soft tissues and rapid blood clearance the Y-90-DPD complex proved to be an excellent candidate for targeting tumor therapy. (C) 2008 Elsevier Ltd. All rights reserved.
T2  - Bioorganic and Medicinal Chemistry
T1  - Labeling, characterization, and in vivo localization of a new Y-90-based phosphonate chelate 2,3-dicarboxypropane-1,1-diphosphonic acid for the treatment of bone metastases: Comparison with Tc-99m-DPD complex
VL  - 16
IS  - 8
SP  - 4457
EP  - 4465
DO  - 10.1016/j.bmc.2008.02.062
ER  - 

@article{
author = "Đokić, Divna Đ. and Janković, Drina and Nikolić, Nadežda S.",
year = "2008",
abstract = "The goal of this investigation was to examine the possibilities for yttrium-90-labeling of the 2,3-dicarboxypropane-1,1-diphosphonic acid (DPD), which is currently labeled with technetium-99m and as a Tc-99m-DPD clinically used as bone imaging agent. Analysis of the complex enclosed the radiochemical quality control methods, biodistribution studies, as well as the determination of pharmacokinetic parameters. The biological behavior of complexes Y-90-DPD, Tc-99m-DPD and Y-90-labeled DPD-kit formulation [Y-90-(Sn)-DPD] in animal model was compared. The labeling conditions were standardized to give the maximum yield, which ranged between 93% and 98%. The examined Y-90 complex could be easily prepared, with an outstanding yield and was also found to be very stable for at least 10 h after Y-90-labeling. Protein binding value was 4.6 +/- 0.7% for Y-90-DPD complex and the complex possess a hydrophilic character. The satisfactory results of Y-90- DPD biodistribution in healthy test animals were obtained; the uptake in the bone was 11-13% ID/g after 24 h depending on the pH value during the preparation. With high skeletal uptake, a minimum uptake in soft tissues and rapid blood clearance the Y-90-DPD complex proved to be an excellent candidate for targeting tumor therapy. (C) 2008 Elsevier Ltd. All rights reserved.",
journal = "Bioorganic and Medicinal Chemistry",
title = "Labeling, characterization, and in vivo localization of a new Y-90-based phosphonate chelate 2,3-dicarboxypropane-1,1-diphosphonic acid for the treatment of bone metastases: Comparison with Tc-99m-DPD complex",
volume = "16",
number = "8",
pages = "4457-4465",
doi = "10.1016/j.bmc.2008.02.062"
}

Đokić, D. Đ., Janković, D.,& Nikolić, N. S.. (2008). Labeling, characterization, and in vivo localization of a new Y-90-based phosphonate chelate 2,3-dicarboxypropane-1,1-diphosphonic acid for the treatment of bone metastases: Comparison with Tc-99m-DPD complex. in Bioorganic and Medicinal Chemistry, 16(8), 4457-4465.
https://doi.org/10.1016/j.bmc.2008.02.062

Đokić DĐ, Janković D, Nikolić NS. Labeling, characterization, and in vivo localization of a new Y-90-based phosphonate chelate 2,3-dicarboxypropane-1,1-diphosphonic acid for the treatment of bone metastases: Comparison with Tc-99m-DPD complex. in Bioorganic and Medicinal Chemistry. 2008;16(8):4457-4465.
doi:10.1016/j.bmc.2008.02.062 .

Đokić, Divna Đ., Janković, Drina, Nikolić, Nadežda S., "Labeling, characterization, and in vivo localization of a new Y-90-based phosphonate chelate 2,3-dicarboxypropane-1,1-diphosphonic acid for the treatment of bone metastases: Comparison with Tc-99m-DPD complex" in Bioorganic and Medicinal Chemistry, 16, no. 8 (2008):4457-4465,
https://doi.org/10.1016/j.bmc.2008.02.062 . .

TY  - JOUR
AU  - Janković, Drina
AU  - Maksin, Tatjana N.
AU  - Đokić, Divna Đ.
AU  - Milonjić, Slobodan K.
AU  - Nikolić, Nadežda S.
AU  - Mirković, Marija D.
AU  - Vranješ-Đurić, Sanja
PY  - 2008
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3578
AB  - Colloidal particle size is an important characteristic to consider when choosing a radiopharmaceutical for diagnosis and therapeutic purposes in nuclear medicine. Photon correlation spectroscopy (PCS) and transmission electron microscopy (TEM) were used to determine the particle-size distribution of (90)Y- and (99m)Tc-labelled antimony trisulfide (Sb(2)S(3)) and tin colloids (Sn-colloid). (90)Y-Sb(2)S(3) and (99m)Tc-Sb(2)S(3) were found to have a diameter of 28.92 +/- 0.14 and 35.61 +/- 0.11 nm, respectively, by PCS. By TEM, (90)Y-Sb(2)S(3) particles were measured to be 14.33 +/- 0.09 nm. (90)Y-labelled Sn colloid were found to exist with a d(v(max1)) of 805 nm and a d(v(max2)) of 2590 nm, by PCS, whereas (99m)Tc-Sn colloid was shown to have more than 80% of radioactive particles of approximately 910 nm by PCS. For (90)Y-labelled Sb(2)S(3) and Sn colloid, a comparison of TEM and PCS indicates that these techniques found significantly different mean diameters. TEM has an excellent resolution necessary for radiocolloid particle-sizing analysis, and it is a desirable size-measuring technique because it is more reliable than PCS.
T2  - Journal of Microscopy, Oxford
T1  - Particle size analysis: (90)Y and (99m)Tc-labelled colloids
VL  - 232
IS  - 3
SP  - 601
EP  - 604
DO  - 10.1111/j.1365-2818.2008.02124.x
ER  - 

@article{
author = "Janković, Drina and Maksin, Tatjana N. and Đokić, Divna Đ. and Milonjić, Slobodan K. and Nikolić, Nadežda S. and Mirković, Marija D. and Vranješ-Đurić, Sanja",
year = "2008",
abstract = "Colloidal particle size is an important characteristic to consider when choosing a radiopharmaceutical for diagnosis and therapeutic purposes in nuclear medicine. Photon correlation spectroscopy (PCS) and transmission electron microscopy (TEM) were used to determine the particle-size distribution of (90)Y- and (99m)Tc-labelled antimony trisulfide (Sb(2)S(3)) and tin colloids (Sn-colloid). (90)Y-Sb(2)S(3) and (99m)Tc-Sb(2)S(3) were found to have a diameter of 28.92 +/- 0.14 and 35.61 +/- 0.11 nm, respectively, by PCS. By TEM, (90)Y-Sb(2)S(3) particles were measured to be 14.33 +/- 0.09 nm. (90)Y-labelled Sn colloid were found to exist with a d(v(max1)) of 805 nm and a d(v(max2)) of 2590 nm, by PCS, whereas (99m)Tc-Sn colloid was shown to have more than 80% of radioactive particles of approximately 910 nm by PCS. For (90)Y-labelled Sb(2)S(3) and Sn colloid, a comparison of TEM and PCS indicates that these techniques found significantly different mean diameters. TEM has an excellent resolution necessary for radiocolloid particle-sizing analysis, and it is a desirable size-measuring technique because it is more reliable than PCS.",
journal = "Journal of Microscopy, Oxford",
title = "Particle size analysis: (90)Y and (99m)Tc-labelled colloids",
volume = "232",
number = "3",
pages = "601-604",
doi = "10.1111/j.1365-2818.2008.02124.x"
}

Janković, D., Maksin, T. N., Đokić, D. Đ., Milonjić, S. K., Nikolić, N. S., Mirković, M. D.,& Vranješ-Đurić, S.. (2008). Particle size analysis: (90)Y and (99m)Tc-labelled colloids. in Journal of Microscopy, Oxford, 232(3), 601-604.
https://doi.org/10.1111/j.1365-2818.2008.02124.x

Janković D, Maksin TN, Đokić DĐ, Milonjić SK, Nikolić NS, Mirković MD, Vranješ-Đurić S. Particle size analysis: (90)Y and (99m)Tc-labelled colloids. in Journal of Microscopy, Oxford. 2008;232(3):601-604.
doi:10.1111/j.1365-2818.2008.02124.x .

Janković, Drina, Maksin, Tatjana N., Đokić, Divna Đ., Milonjić, Slobodan K., Nikolić, Nadežda S., Mirković, Marija D., Vranješ-Đurić, Sanja, "Particle size analysis: (90)Y and (99m)Tc-labelled colloids" in Journal of Microscopy, Oxford, 232, no. 3 (2008):601-604,
https://doi.org/10.1111/j.1365-2818.2008.02124.x . .

TY  - JOUR
AU  - Maksin, Tatjana N.
AU  - Đokić, Divna Đ.
AU  - Janković, Drina
AU  - Djordjevc, A.
AU  - Nešković, Olivera M.
PY  - 2007
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3265
AB  - The biological behavior of fullerene derivatives shows their considerable potential for medical application. Polyhidroxilated, water soluble fullerenol C-60(OH)(22). used in these studies, was synthesized by procedure complete substitution of bromine atoms from polybromine derivatives C60Br24 in alkaline media. In order to investigate the pharmacological behaviour and metabolism of the fullerenol, quickly and conveniently, we present the way and possibilities for its labelling with Tc-99m (T-1/2=6.02h, E-n=141keV), which bind to the outside, leaving the cage intact. Two different labelling approaches with technetium-99m were performed: direct labelling by tin (II) chloride method and labelling with Tc-99m(I) using [Tc-99m(CO)(3)(H2O)(3)](+) precursor. The radiochemical studies results have shown that content of free (TcO4-)-Tc-99m in the samples was depend on fullerenol-stannous chloride ratio and increased if ratio was higher. HPLC quality control results of Tc-99m(CO)(3)-[C-60(OH)(22)] have shown that the labelling yield, in alkaly media, was 95.35%. Protein binding to HA was species-dependent process. The biological behaviour of labelled fullerenol were different in dependence of labelling method and the time of sacrificed of animals. From recent investigations it can be concluded that oxidation state in technetium coordination complexes has a great impact on in vitro and in vivo behaviour of the these complexes.
T2  - Journal of Optoelectronics and Advanced Materials
T1  - Comparison of some physico-chemical parameters and biological behaviour of fullerenol labelled with technetium-99m
VL  - 9
IS  - 8
SP  - 2571
EP  - 2577
UR  - https://hdl.handle.net/21.15107/rcub_vinar_3265
ER  - 

@article{
author = "Maksin, Tatjana N. and Đokić, Divna Đ. and Janković, Drina and Djordjevc, A. and Nešković, Olivera M.",
year = "2007",
abstract = "The biological behavior of fullerene derivatives shows their considerable potential for medical application. Polyhidroxilated, water soluble fullerenol C-60(OH)(22). used in these studies, was synthesized by procedure complete substitution of bromine atoms from polybromine derivatives C60Br24 in alkaline media. In order to investigate the pharmacological behaviour and metabolism of the fullerenol, quickly and conveniently, we present the way and possibilities for its labelling with Tc-99m (T-1/2=6.02h, E-n=141keV), which bind to the outside, leaving the cage intact. Two different labelling approaches with technetium-99m were performed: direct labelling by tin (II) chloride method and labelling with Tc-99m(I) using [Tc-99m(CO)(3)(H2O)(3)](+) precursor. The radiochemical studies results have shown that content of free (TcO4-)-Tc-99m in the samples was depend on fullerenol-stannous chloride ratio and increased if ratio was higher. HPLC quality control results of Tc-99m(CO)(3)-[C-60(OH)(22)] have shown that the labelling yield, in alkaly media, was 95.35%. Protein binding to HA was species-dependent process. The biological behaviour of labelled fullerenol were different in dependence of labelling method and the time of sacrificed of animals. From recent investigations it can be concluded that oxidation state in technetium coordination complexes has a great impact on in vitro and in vivo behaviour of the these complexes.",
journal = "Journal of Optoelectronics and Advanced Materials",
title = "Comparison of some physico-chemical parameters and biological behaviour of fullerenol labelled with technetium-99m",
volume = "9",
number = "8",
pages = "2571-2577",
url = "https://hdl.handle.net/21.15107/rcub_vinar_3265"
}

Maksin, T. N., Đokić, D. Đ., Janković, D., Djordjevc, A.,& Nešković, O. M.. (2007). Comparison of some physico-chemical parameters and biological behaviour of fullerenol labelled with technetium-99m. in Journal of Optoelectronics and Advanced Materials, 9(8), 2571-2577.
https://hdl.handle.net/21.15107/rcub_vinar_3265

Maksin TN, Đokić DĐ, Janković D, Djordjevc A, Nešković OM. Comparison of some physico-chemical parameters and biological behaviour of fullerenol labelled with technetium-99m. in Journal of Optoelectronics and Advanced Materials. 2007;9(8):2571-2577.
https://hdl.handle.net/21.15107/rcub_vinar_3265 .

Maksin, Tatjana N., Đokić, Divna Đ., Janković, Drina, Djordjevc, A., Nešković, Olivera M., "Comparison of some physico-chemical parameters and biological behaviour of fullerenol labelled with technetium-99m" in Journal of Optoelectronics and Advanced Materials, 9, no. 8 (2007):2571-2577,
https://hdl.handle.net/21.15107/rcub_vinar_3265 .

TY  - JOUR
AU  - Đokić, Divna Đ.
AU  - Janković, Drina
PY  - 2007
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3192
AB  - The Tc-99m-labelling of the amino acids tyrosine (Tyr) and lysine (Lys), fundamental building blocks of proteins and peptides, as well as biological properties of the labelled compounds are investigated. Three different approaches for the labelling with Tc-99m have been investigated: direct reduction with stannous tin in the presence of the amino acids, the preformed chelate approach through polydentate chelates DTPA and GH, and the organometallic approach using [Tc-99m(CO)(3)(H2O)(3)](+) precursor. The direct labelling approach was not successful and the yield was poor. In the presence of DTPA and GH, the labelling efficiency was between 43.6 and 97.8%, depending on the amino acid and the polydentate chelate. The use of [Tc-99m(CO)(3)(H2O)(3)](+) precursor point at the formation of Tc-99m(l) co-ordinated complexes with high yield. In this approach, pH and heating influenced the yields. The results of organ distribution study for [Tc-99m(Tyr)(H2O)(CO)(3)] and [Tc-99m(Lys)(H2O)(CO)(3)] show accumulation in liver, kidneys and intestine., Copyright (C) 2007 John Wiley and Sons, Ltd.
T2  - Journal of Labelled Compounds and Radiopharmaceuticals
T1  - Biological evaluation and comparison of three different procedures for labelling of amino acids tyrosine and lysine with technetium-99m
VL  - 50
IS  - 3-4
SP  - 155
EP  - 163
DO  - 10.1002/jlcr.1205
ER  - 

@article{
author = "Đokić, Divna Đ. and Janković, Drina",
year = "2007",
abstract = "The Tc-99m-labelling of the amino acids tyrosine (Tyr) and lysine (Lys), fundamental building blocks of proteins and peptides, as well as biological properties of the labelled compounds are investigated. Three different approaches for the labelling with Tc-99m have been investigated: direct reduction with stannous tin in the presence of the amino acids, the preformed chelate approach through polydentate chelates DTPA and GH, and the organometallic approach using [Tc-99m(CO)(3)(H2O)(3)](+) precursor. The direct labelling approach was not successful and the yield was poor. In the presence of DTPA and GH, the labelling efficiency was between 43.6 and 97.8%, depending on the amino acid and the polydentate chelate. The use of [Tc-99m(CO)(3)(H2O)(3)](+) precursor point at the formation of Tc-99m(l) co-ordinated complexes with high yield. In this approach, pH and heating influenced the yields. The results of organ distribution study for [Tc-99m(Tyr)(H2O)(CO)(3)] and [Tc-99m(Lys)(H2O)(CO)(3)] show accumulation in liver, kidneys and intestine., Copyright (C) 2007 John Wiley and Sons, Ltd.",
journal = "Journal of Labelled Compounds and Radiopharmaceuticals",
title = "Biological evaluation and comparison of three different procedures for labelling of amino acids tyrosine and lysine with technetium-99m",
volume = "50",
number = "3-4",
pages = "155-163",
doi = "10.1002/jlcr.1205"
}

Đokić, D. Đ.,& Janković, D.. (2007). Biological evaluation and comparison of three different procedures for labelling of amino acids tyrosine and lysine with technetium-99m. in Journal of Labelled Compounds and Radiopharmaceuticals, 50(3-4), 155-163.
https://doi.org/10.1002/jlcr.1205

Đokić DĐ, Janković D. Biological evaluation and comparison of three different procedures for labelling of amino acids tyrosine and lysine with technetium-99m. in Journal of Labelled Compounds and Radiopharmaceuticals. 2007;50(3-4):155-163.
doi:10.1002/jlcr.1205 .

Đokić, Divna Đ., Janković, Drina, "Biological evaluation and comparison of three different procedures for labelling of amino acids tyrosine and lysine with technetium-99m" in Journal of Labelled Compounds and Radiopharmaceuticals, 50, no. 3-4 (2007):155-163,
https://doi.org/10.1002/jlcr.1205 . .

TY  - JOUR
AU  - Babić, Biljana M.
AU  - Kaluđerović, Branka V.
AU  - Đokić, Divna Đ.
AU  - Krstajic, N
PY  - 2005
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/6533
AB  - Resorcinol-formaldehyde (RF) cryogels were synthesized by sol-gel polycondensation of resorcinol with formaldehyde and freeze-drying carried out with t-butanol. Carbon cryogels were obtained by pyrolyzing RF cryogels in an inert atmosphere. Characterization by nitrogen adsorption showed that carbon cryogels were micro- and mesoporous materials with high surface areas (500 m(2)/g LT S-BET LT 700 m(2)/g). Cyclic voltammetry experiments at various scan rates (2 to 200 mV s(-1)) were carried out to study the electrical double-layer charging of carbon cryogel electrodes in 0.5 mol dm(-3) HClO4 solution. It has been demonstrated that the total specific capacitance can further be divided into mesoporous and microporous specific capacitance by analyzing the linear dependence of the specific capacitance (C) on the reciprocal of the square root of the potential scan rate (nu(-1/2)), as well as linear dependence of the reciprocal specific charge (1/C) on the square root of the potential scan rate (nu(1/2)).
T2  - Materials Science Forum
T1  - Characterization of carbon cryogel synthesized by sol-gel polycondensation and freeze-drying
VL  - 494
SP  - 327
EP  - 332
DO  - 10.4028/www.scientific.net/MSF.494.327
ER  - 

@article{
author = "Babić, Biljana M. and Kaluđerović, Branka V. and Đokić, Divna Đ. and Krstajic, N",
year = "2005",
abstract = "Resorcinol-formaldehyde (RF) cryogels were synthesized by sol-gel polycondensation of resorcinol with formaldehyde and freeze-drying carried out with t-butanol. Carbon cryogels were obtained by pyrolyzing RF cryogels in an inert atmosphere. Characterization by nitrogen adsorption showed that carbon cryogels were micro- and mesoporous materials with high surface areas (500 m(2)/g LT S-BET LT 700 m(2)/g). Cyclic voltammetry experiments at various scan rates (2 to 200 mV s(-1)) were carried out to study the electrical double-layer charging of carbon cryogel electrodes in 0.5 mol dm(-3) HClO4 solution. It has been demonstrated that the total specific capacitance can further be divided into mesoporous and microporous specific capacitance by analyzing the linear dependence of the specific capacitance (C) on the reciprocal of the square root of the potential scan rate (nu(-1/2)), as well as linear dependence of the reciprocal specific charge (1/C) on the square root of the potential scan rate (nu(1/2)).",
journal = "Materials Science Forum",
title = "Characterization of carbon cryogel synthesized by sol-gel polycondensation and freeze-drying",
volume = "494",
pages = "327-332",
doi = "10.4028/www.scientific.net/MSF.494.327"
}

Babić, B. M., Kaluđerović, B. V., Đokić, D. Đ.,& Krstajic, N.. (2005). Characterization of carbon cryogel synthesized by sol-gel polycondensation and freeze-drying. in Materials Science Forum, 494, 327-332.
https://doi.org/10.4028/www.scientific.net/MSF.494.327

Babić BM, Kaluđerović BV, Đokić DĐ, Krstajic N. Characterization of carbon cryogel synthesized by sol-gel polycondensation and freeze-drying. in Materials Science Forum. 2005;494:327-332.
doi:10.4028/www.scientific.net/MSF.494.327 .

Babić, Biljana M., Kaluđerović, Branka V., Đokić, Divna Đ., Krstajic, N, "Characterization of carbon cryogel synthesized by sol-gel polycondensation and freeze-drying" in Materials Science Forum, 494 (2005):327-332,
https://doi.org/10.4028/www.scientific.net/MSF.494.327 . .

TY  - JOUR
AU  - Janković, Drina
AU  - Đokić, Divna Đ.
PY  - 2005
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2886
AB  - Aim To investigate the influence of certain cytotoxic drugs on the organ uptake of the following Tc-99m-radiopharmaceuticals: Tc-99m-2,3-dicarboxypropane-1,1-diphosphonic acid (Tc-99m-DPD), Tc-99m-meso-2,3-dimercaptosuccinic acid (Tc-99m-DMSA), (TC)-T-99m-tin colloid and Tc-99m-macroaggregated albumin Tc-(99m-MAA). Methotrexate sodium and cyclophosphamide were used as models to evaluate these effects . Methods Two groups of healthy male Wistar rats were treated separately by oral application of the drugs for 7 days. On the eighth day, each of the Tc-99m-radiopharmaceuticals was applied in a separate group of treated animals. They were sacrificed at different time intervals and the radioactivity in the organs of interest was measured. The organ uptake of the Tc-99m-radiopharmaceuticals in an additional control group of animals was also studied. Results The results obtained showed an alteration in the organ uptake of (TC)-T-99m-radiopharmaceuticals in animals treated with cytotoxic drugs. In rats treated with methotrexate sodium, there was a higher uptake of Tc-99m-DMSA in the bones, stomach and intestine, a higher uptake of Tc-99m-DPD in the bones, intestine, blood and muscle, a lower uptake of (TC)-T-99m-tin colloid in the liver and a lower accumulation of Tc-99m-MAA in the lungs. Cyclophosphamide-treated animals showed enhanced uptake of Tc-99m-DMSA in the kidneys, a twofold enhanced uptake of Tc-99m-DPD in all organs except the stomach, a decreased uptake of Tc-99m-tin colloid in the lungs, spleen and kidneys and a significantly decreased uptake of Tc-99m-MAA in the lungs. Conclusion These results confirm that both methotrexate sodium and cyclophosphamide may alter the organ uptake of Tc-99m-radiopharmaceuticals in experimental animals. and COPY; 2005 Lippincott Williams and Wilkins.
T2  - Nuclear Medicine Communications
T1  - Alteration of the organ uptake of the Tc-99m-radiopharmaceuticals, Tc-99m-DPD, Tc-99m-DMSA, Tc-99m-tin colloid and Tc-99m-MAA, induced by the applied cytotoxic drugs methotrexate sodium and cyclophosphamide
VL  - 26
IS  - 5
SP  - 415
EP  - 419
UR  - https://hdl.handle.net/21.15107/rcub_vinar_2886
ER  - 

@article{
author = "Janković, Drina and Đokić, Divna Đ.",
year = "2005",
abstract = "Aim To investigate the influence of certain cytotoxic drugs on the organ uptake of the following Tc-99m-radiopharmaceuticals: Tc-99m-2,3-dicarboxypropane-1,1-diphosphonic acid (Tc-99m-DPD), Tc-99m-meso-2,3-dimercaptosuccinic acid (Tc-99m-DMSA), (TC)-T-99m-tin colloid and Tc-99m-macroaggregated albumin Tc-(99m-MAA). Methotrexate sodium and cyclophosphamide were used as models to evaluate these effects . Methods Two groups of healthy male Wistar rats were treated separately by oral application of the drugs for 7 days. On the eighth day, each of the Tc-99m-radiopharmaceuticals was applied in a separate group of treated animals. They were sacrificed at different time intervals and the radioactivity in the organs of interest was measured. The organ uptake of the Tc-99m-radiopharmaceuticals in an additional control group of animals was also studied. Results The results obtained showed an alteration in the organ uptake of (TC)-T-99m-radiopharmaceuticals in animals treated with cytotoxic drugs. In rats treated with methotrexate sodium, there was a higher uptake of Tc-99m-DMSA in the bones, stomach and intestine, a higher uptake of Tc-99m-DPD in the bones, intestine, blood and muscle, a lower uptake of (TC)-T-99m-tin colloid in the liver and a lower accumulation of Tc-99m-MAA in the lungs. Cyclophosphamide-treated animals showed enhanced uptake of Tc-99m-DMSA in the kidneys, a twofold enhanced uptake of Tc-99m-DPD in all organs except the stomach, a decreased uptake of Tc-99m-tin colloid in the lungs, spleen and kidneys and a significantly decreased uptake of Tc-99m-MAA in the lungs. Conclusion These results confirm that both methotrexate sodium and cyclophosphamide may alter the organ uptake of Tc-99m-radiopharmaceuticals in experimental animals. and COPY; 2005 Lippincott Williams and Wilkins.",
journal = "Nuclear Medicine Communications",
title = "Alteration of the organ uptake of the Tc-99m-radiopharmaceuticals, Tc-99m-DPD, Tc-99m-DMSA, Tc-99m-tin colloid and Tc-99m-MAA, induced by the applied cytotoxic drugs methotrexate sodium and cyclophosphamide",
volume = "26",
number = "5",
pages = "415-419",
url = "https://hdl.handle.net/21.15107/rcub_vinar_2886"
}

Janković, D.,& Đokić, D. Đ.. (2005). Alteration of the organ uptake of the Tc-99m-radiopharmaceuticals, Tc-99m-DPD, Tc-99m-DMSA, Tc-99m-tin colloid and Tc-99m-MAA, induced by the applied cytotoxic drugs methotrexate sodium and cyclophosphamide. in Nuclear Medicine Communications, 26(5), 415-419.
https://hdl.handle.net/21.15107/rcub_vinar_2886

Janković D, Đokić DĐ. Alteration of the organ uptake of the Tc-99m-radiopharmaceuticals, Tc-99m-DPD, Tc-99m-DMSA, Tc-99m-tin colloid and Tc-99m-MAA, induced by the applied cytotoxic drugs methotrexate sodium and cyclophosphamide. in Nuclear Medicine Communications. 2005;26(5):415-419.
https://hdl.handle.net/21.15107/rcub_vinar_2886 .

Janković, Drina, Đokić, Divna Đ., "Alteration of the organ uptake of the Tc-99m-radiopharmaceuticals, Tc-99m-DPD, Tc-99m-DMSA, Tc-99m-tin colloid and Tc-99m-MAA, induced by the applied cytotoxic drugs methotrexate sodium and cyclophosphamide" in Nuclear Medicine Communications, 26, no. 5 (2005):415-419,
https://hdl.handle.net/21.15107/rcub_vinar_2886 .

TY  - JOUR
AU  - Babić, Biljana M.
AU  - Đokić, Divna Đ.
AU  - Krstajic, N
PY  - 2005
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2862
AB  - Resorcinol-formaldehyde (RF) cryogels were synthesized by the sol-gel polycondensation of resorcinol (R) with formaldehyde (F) and freeze-drying was carried out with t-butanol. Carbon cryogels were obtained by pyrolyzing RF cryogels in an inert atmosphere. Characterization by nitrogen adsorption showed that the carbon cryogels were micro and mesoporous materials with high specific surface areas (S-BET approximate to 550 m(2)/g). Cyclic voltammetry experiments at various scan rates (2 to 200 mV s(-1)) were performed to study the electrical double-layer charging of carbon cryogel electrodes in 0.5 mol dm(-3) HClO4 solution. It has been demonstrated that it is possible to sub-divide the total specific capacitance into the mesoporous and the microporous specific capacitance by analyzing the linear dependence of the charge (q) on the reciprocal of the square root of the potential scan rate (v(-1/2)), and the linear dependence of the reciprocal charge (l/q) on the square root of the potential scan rate (v(-1/2)). The specific capacitance was found to be constant over a wide range of sample weight (12.5 to 50.0 mug) and a very promising specific capacitance value of 150 F/g, was found for this material operating in an acidic 0.5 mol dm(-3) HClO4 solution at room temperature.
T2  - Journal of the Serbian Chemical Society
T1  - Characterization of carbon cryogels synthesized by sol-gel polycondensation
VL  - 70
IS  - 1
SP  - 21
EP  - 31
DO  - 10.2298/JSC0501021B
ER  - 

@article{
author = "Babić, Biljana M. and Đokić, Divna Đ. and Krstajic, N",
year = "2005",
abstract = "Resorcinol-formaldehyde (RF) cryogels were synthesized by the sol-gel polycondensation of resorcinol (R) with formaldehyde (F) and freeze-drying was carried out with t-butanol. Carbon cryogels were obtained by pyrolyzing RF cryogels in an inert atmosphere. Characterization by nitrogen adsorption showed that the carbon cryogels were micro and mesoporous materials with high specific surface areas (S-BET approximate to 550 m(2)/g). Cyclic voltammetry experiments at various scan rates (2 to 200 mV s(-1)) were performed to study the electrical double-layer charging of carbon cryogel electrodes in 0.5 mol dm(-3) HClO4 solution. It has been demonstrated that it is possible to sub-divide the total specific capacitance into the mesoporous and the microporous specific capacitance by analyzing the linear dependence of the charge (q) on the reciprocal of the square root of the potential scan rate (v(-1/2)), and the linear dependence of the reciprocal charge (l/q) on the square root of the potential scan rate (v(-1/2)). The specific capacitance was found to be constant over a wide range of sample weight (12.5 to 50.0 mug) and a very promising specific capacitance value of 150 F/g, was found for this material operating in an acidic 0.5 mol dm(-3) HClO4 solution at room temperature.",
journal = "Journal of the Serbian Chemical Society",
title = "Characterization of carbon cryogels synthesized by sol-gel polycondensation",
volume = "70",
number = "1",
pages = "21-31",
doi = "10.2298/JSC0501021B"
}

Babić, B. M., Đokić, D. Đ.,& Krstajic, N.. (2005). Characterization of carbon cryogels synthesized by sol-gel polycondensation. in Journal of the Serbian Chemical Society, 70(1), 21-31.
https://doi.org/10.2298/JSC0501021B

Babić BM, Đokić DĐ, Krstajic N. Characterization of carbon cryogels synthesized by sol-gel polycondensation. in Journal of the Serbian Chemical Society. 2005;70(1):21-31.
doi:10.2298/JSC0501021B .

Babić, Biljana M., Đokić, Divna Đ., Krstajic, N, "Characterization of carbon cryogels synthesized by sol-gel polycondensation" in Journal of the Serbian Chemical Society, 70, no. 1 (2005):21-31,
https://doi.org/10.2298/JSC0501021B . .

TY  - CONF
AU  - Jaksic, E.
AU  - Beatovic, S.
AU  - Đokić, Divna Đ.
AU  - Janković, Drina
AU  - Lezaic, V.
AU  - Han, R.
PY  - 2005
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2734
C3  - European Journal of Nuclear Medicine and Molecular Imaging
T1  - Tc-99m PAH Renography: Clinical Studies
VL  - 32
SP  - S246
EP  - S246
UR  - https://hdl.handle.net/21.15107/rcub_vinar_2734
ER  - 

@conference{
author = "Jaksic, E. and Beatovic, S. and Đokić, Divna Đ. and Janković, Drina and Lezaic, V. and Han, R.",
year = "2005",
journal = "European Journal of Nuclear Medicine and Molecular Imaging",
title = "Tc-99m PAH Renography: Clinical Studies",
volume = "32",
pages = "S246-S246",
url = "https://hdl.handle.net/21.15107/rcub_vinar_2734"
}

Jaksic, E., Beatovic, S., Đokić, D. Đ., Janković, D., Lezaic, V.,& Han, R.. (2005). Tc-99m PAH Renography: Clinical Studies. in European Journal of Nuclear Medicine and Molecular Imaging, 32, S246-S246.
https://hdl.handle.net/21.15107/rcub_vinar_2734

Jaksic E, Beatovic S, Đokić DĐ, Janković D, Lezaic V, Han R. Tc-99m PAH Renography: Clinical Studies. in European Journal of Nuclear Medicine and Molecular Imaging. 2005;32:S246-S246.
https://hdl.handle.net/21.15107/rcub_vinar_2734 .

Jaksic, E., Beatovic, S., Đokić, Divna Đ., Janković, Drina, Lezaic, V., Han, R., "Tc-99m PAH Renography: Clinical Studies" in European Journal of Nuclear Medicine and Molecular Imaging, 32 (2005):S246-S246,
https://hdl.handle.net/21.15107/rcub_vinar_2734 .

TY  - CONF
AU  - Jaksic, E
AU  - Beatovic, S
AU  - Đokić, Divna Đ.
AU  - Janković, Drina
AU  - Lezajic, V
AU  - Han, R
PY  - 2004
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/6462
C3  - European Journal of Nuclear Medicine and Molecular Imaging
T1  - Comparative study of renal scintigraphy and clearance with Tc-99m p-aminohippuric acid, DTPA and MAG3
VL  - 31
SP  - S227
EP  - S227
UR  - https://hdl.handle.net/21.15107/rcub_vinar_6462
ER  - 

@conference{
author = "Jaksic, E and Beatovic, S and Đokić, Divna Đ. and Janković, Drina and Lezajic, V and Han, R",
year = "2004",
journal = "European Journal of Nuclear Medicine and Molecular Imaging",
title = "Comparative study of renal scintigraphy and clearance with Tc-99m p-aminohippuric acid, DTPA and MAG3",
volume = "31",
pages = "S227-S227",
url = "https://hdl.handle.net/21.15107/rcub_vinar_6462"
}

Jaksic, E., Beatovic, S., Đokić, D. Đ., Janković, D., Lezajic, V.,& Han, R.. (2004). Comparative study of renal scintigraphy and clearance with Tc-99m p-aminohippuric acid, DTPA and MAG3. in European Journal of Nuclear Medicine and Molecular Imaging, 31, S227-S227.
https://hdl.handle.net/21.15107/rcub_vinar_6462

Jaksic E, Beatovic S, Đokić DĐ, Janković D, Lezajic V, Han R. Comparative study of renal scintigraphy and clearance with Tc-99m p-aminohippuric acid, DTPA and MAG3. in European Journal of Nuclear Medicine and Molecular Imaging. 2004;31:S227-S227.
https://hdl.handle.net/21.15107/rcub_vinar_6462 .

Jaksic, E, Beatovic, S, Đokić, Divna Đ., Janković, Drina, Lezajic, V, Han, R, "Comparative study of renal scintigraphy and clearance with Tc-99m p-aminohippuric acid, DTPA and MAG3" in European Journal of Nuclear Medicine and Molecular Imaging, 31 (2004):S227-S227,
https://hdl.handle.net/21.15107/rcub_vinar_6462 .

TY  - CONF
AU  - Janković, Drina
AU  - Đokić, Divna Đ.
PY  - 2004
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9601
AB  - The complex equilibrium in tin(II)-p-aminohippuric acid (PAH) solutions in perchlorate medium was investigated. HPLC, spectrophotometric and pH-metric methods were used. The experimental results have shown that week mononuclear complex of the general composition PAH/Sn(II)=1/1 was formed.
PB  - Society of Physical Chemists of Serbia
C3  - Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry
T1  - HPLC and spectrophotometric investigation of the formation of Sn(II)-p-aminohippuric acid complex in perchlorate medium
VL  - 2
SP  - 793
EP  - 795
UR  - https://hdl.handle.net/21.15107/rcub_vinar_9601
ER  - 

@conference{
author = "Janković, Drina and Đokić, Divna Đ.",
year = "2004",
abstract = "The complex equilibrium in tin(II)-p-aminohippuric acid (PAH) solutions in perchlorate medium was investigated. HPLC, spectrophotometric and pH-metric methods were used. The experimental results have shown that week mononuclear complex of the general composition PAH/Sn(II)=1/1 was formed.",
publisher = "Society of Physical Chemists of Serbia",
journal = "Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry",
title = "HPLC and spectrophotometric investigation of the formation of Sn(II)-p-aminohippuric acid complex in perchlorate medium",
volume = "2",
pages = "793-795",
url = "https://hdl.handle.net/21.15107/rcub_vinar_9601"
}

Janković, D.,& Đokić, D. Đ.. (2004). HPLC and spectrophotometric investigation of the formation of Sn(II)-p-aminohippuric acid complex in perchlorate medium. in Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry
Society of Physical Chemists of Serbia., 2, 793-795.
https://hdl.handle.net/21.15107/rcub_vinar_9601

Janković D, Đokić DĐ. HPLC and spectrophotometric investigation of the formation of Sn(II)-p-aminohippuric acid complex in perchlorate medium. in Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry. 2004;2:793-795.
https://hdl.handle.net/21.15107/rcub_vinar_9601 .

Janković, Drina, Đokić, Divna Đ., "HPLC and spectrophotometric investigation of the formation of Sn(II)-p-aminohippuric acid complex in perchlorate medium" in Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry, 2 (2004):793-795,
https://hdl.handle.net/21.15107/rcub_vinar_9601 .

TY  - CONF
AU  - Stamenković, Ljiljana Lj.
AU  - Đokić, Divna Đ.
PY  - 2004
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9530
AB  - The possibilities for labelling of different phosphate ligands with technetium-99m through [99m Tc(CO)3(H2O)3] +  precursor were investigated. The HPLC results have shown that hydrophilic organometallic [ 99mTc(CO)3(H2O)3] +  precursor allows forming of Tc (I) complexes with different phosphate ligands, based on the tricarbonyltechnetium (I) core.
PB  - Society of Physical Chemists of Serbia
C3  - Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry
T1  - Tricarbonyl technetium(I) complexes with different phosphate ligands
VL  - 1
SP  - 450
EP  - 452
UR  - https://hdl.handle.net/21.15107/rcub_vinar_9530
ER  - 

@conference{
author = "Stamenković, Ljiljana Lj. and Đokić, Divna Đ.",
year = "2004",
abstract = "The possibilities for labelling of different phosphate ligands with technetium-99m through [99m Tc(CO)3(H2O)3] +  precursor were investigated. The HPLC results have shown that hydrophilic organometallic [ 99mTc(CO)3(H2O)3] +  precursor allows forming of Tc (I) complexes with different phosphate ligands, based on the tricarbonyltechnetium (I) core.",
publisher = "Society of Physical Chemists of Serbia",
journal = "Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry",
title = "Tricarbonyl technetium(I) complexes with different phosphate ligands",
volume = "1",
pages = "450-452",
url = "https://hdl.handle.net/21.15107/rcub_vinar_9530"
}

Stamenković, L. Lj.,& Đokić, D. Đ.. (2004). Tricarbonyl technetium(I) complexes with different phosphate ligands. in Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry
Society of Physical Chemists of Serbia., 1, 450-452.
https://hdl.handle.net/21.15107/rcub_vinar_9530

Stamenković LL, Đokić DĐ. Tricarbonyl technetium(I) complexes with different phosphate ligands. in Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry. 2004;1:450-452.
https://hdl.handle.net/21.15107/rcub_vinar_9530 .

Stamenković, Ljiljana Lj., Đokić, Divna Đ., "Tricarbonyl technetium(I) complexes with different phosphate ligands" in Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry, 1 (2004):450-452,
https://hdl.handle.net/21.15107/rcub_vinar_9530 .

TY  - JOUR
AU  - Janković, Drina
AU  - Đokić, Divna Đ.
PY  - 2004
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2850
AB  - The complex equilibrium in tin (II)-p-aminohippuric acid (PAH) solutions in perchlorate medium was investigated. The interaction between Sn (II)-ion and PAH was studied with the purpose to establish whether PAH could form complex with, Sn (II)-ion during the labeling with technetium-99m. HPLC, spectrophotometric and pH-metric methods were used. Dissociation constants of PAH, thermodynamic parameters of PAH dissociation, as well as stability constant of tin (II)-PAH were determined. The values of thermodynamic dissociation constants of PAH were 4.25, 4.19 and 4.15 at 295, 302 and 310 K respectively. The calculated thermodynamic values DeltaGdegrees, DeltaHdegrees and DeltaSdegrees, were -24.01 KJ mol(-1), -12.44 KJ mol(-1) and 39.22 Jmol(-1) K-1 at 295 K respectively. Sn (II)-ion exhibits only a weak interaction with PAH in the pH range 2.0 divided by 3.7, e.g. in the Sn-PAH solution a weak complex with high degree of dissociation was obtained. The treatment of spectral data referring to Sn-PAH solutions indicates the formation of a mononuclear complex [SnPAH](+). Mathematical analysis of experimental data indicated that the best fit of the potentiometric data was achieved by assuming the formation of a mixed hydrolytic complex [Sn(OH)PAH]. The calculated value of the stability constant was: log beta(1,-1.1) = 0.95 +/- 0.11 at 298 K.
T2  - Reviews in Analytical Chemistry
T1  - Investigation of complex equilibria in solutions of p-aminohippuric acid and tin (II) ion in perchlorate medium
VL  - 23
IS  - 2
SP  - 87
EP  - 105
UR  - https://hdl.handle.net/21.15107/rcub_vinar_2850
ER  - 

@article{
author = "Janković, Drina and Đokić, Divna Đ.",
year = "2004",
abstract = "The complex equilibrium in tin (II)-p-aminohippuric acid (PAH) solutions in perchlorate medium was investigated. The interaction between Sn (II)-ion and PAH was studied with the purpose to establish whether PAH could form complex with, Sn (II)-ion during the labeling with technetium-99m. HPLC, spectrophotometric and pH-metric methods were used. Dissociation constants of PAH, thermodynamic parameters of PAH dissociation, as well as stability constant of tin (II)-PAH were determined. The values of thermodynamic dissociation constants of PAH were 4.25, 4.19 and 4.15 at 295, 302 and 310 K respectively. The calculated thermodynamic values DeltaGdegrees, DeltaHdegrees and DeltaSdegrees, were -24.01 KJ mol(-1), -12.44 KJ mol(-1) and 39.22 Jmol(-1) K-1 at 295 K respectively. Sn (II)-ion exhibits only a weak interaction with PAH in the pH range 2.0 divided by 3.7, e.g. in the Sn-PAH solution a weak complex with high degree of dissociation was obtained. The treatment of spectral data referring to Sn-PAH solutions indicates the formation of a mononuclear complex [SnPAH](+). Mathematical analysis of experimental data indicated that the best fit of the potentiometric data was achieved by assuming the formation of a mixed hydrolytic complex [Sn(OH)PAH]. The calculated value of the stability constant was: log beta(1,-1.1) = 0.95 +/- 0.11 at 298 K.",
journal = "Reviews in Analytical Chemistry",
title = "Investigation of complex equilibria in solutions of p-aminohippuric acid and tin (II) ion in perchlorate medium",
volume = "23",
number = "2",
pages = "87-105",
url = "https://hdl.handle.net/21.15107/rcub_vinar_2850"
}

Janković, D.,& Đokić, D. Đ.. (2004). Investigation of complex equilibria in solutions of p-aminohippuric acid and tin (II) ion in perchlorate medium. in Reviews in Analytical Chemistry, 23(2), 87-105.
https://hdl.handle.net/21.15107/rcub_vinar_2850

Janković D, Đokić DĐ. Investigation of complex equilibria in solutions of p-aminohippuric acid and tin (II) ion in perchlorate medium. in Reviews in Analytical Chemistry. 2004;23(2):87-105.
https://hdl.handle.net/21.15107/rcub_vinar_2850 .

Janković, Drina, Đokić, Divna Đ., "Investigation of complex equilibria in solutions of p-aminohippuric acid and tin (II) ion in perchlorate medium" in Reviews in Analytical Chemistry, 23, no. 2 (2004):87-105,
https://hdl.handle.net/21.15107/rcub_vinar_2850 .

TY  - JOUR
AU  - Đokić, Divna Đ.
AU  - Janković, Drina
AU  - Stamenkovic, LL
AU  - Pirmettis, Ioannis
PY  - 2004
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2770
AB  - The confirmation that N-substituted imidodiacetic acids, as small and simple ligand systems containing amines and carboxylic acids, could be coordinated to the tricarbonyl core and form inert complexes with [Tc-99m (CO)(3)(H2O)(3)](+). is demonstrated. The HPLC quality control results of Tc-99m-carbonyl tagged IDA molecules, performed by gradient HPLC, have shown that HIDA, EHIDA and p-butyl-IDA form complexes with [Tc-99m(CO)(3)(H2O)(3)](+), with a labeling yield of similar to90% for each of Tc-99m(CO)(3) IDA derivatives. However, the changes in the structure of labeled compounds, e.g., EHIDA, influence the changes in the biological behavior. In comparison with Tc-99m-EHIDA, the biliary excretion of Tc-99m(CO)(3) EHIDA was lower, but the urinary excretion higher.
T2  - Journal of Radioanalytical and Nuclear Chemistry
T1  - Chemical and biological evaluation of Tc-99m (CO)(3) and Tc-99m complexes of some IDA derivatives
VL  - 260
IS  - 3
SP  - 471
EP  - 476
DO  - 10.1023/B:JRNC.0000028204.03708.89
ER  - 

@article{
author = "Đokić, Divna Đ. and Janković, Drina and Stamenkovic, LL and Pirmettis, Ioannis",
year = "2004",
abstract = "The confirmation that N-substituted imidodiacetic acids, as small and simple ligand systems containing amines and carboxylic acids, could be coordinated to the tricarbonyl core and form inert complexes with [Tc-99m (CO)(3)(H2O)(3)](+). is demonstrated. The HPLC quality control results of Tc-99m-carbonyl tagged IDA molecules, performed by gradient HPLC, have shown that HIDA, EHIDA and p-butyl-IDA form complexes with [Tc-99m(CO)(3)(H2O)(3)](+), with a labeling yield of similar to90% for each of Tc-99m(CO)(3) IDA derivatives. However, the changes in the structure of labeled compounds, e.g., EHIDA, influence the changes in the biological behavior. In comparison with Tc-99m-EHIDA, the biliary excretion of Tc-99m(CO)(3) EHIDA was lower, but the urinary excretion higher.",
journal = "Journal of Radioanalytical and Nuclear Chemistry",
title = "Chemical and biological evaluation of Tc-99m (CO)(3) and Tc-99m complexes of some IDA derivatives",
volume = "260",
number = "3",
pages = "471-476",
doi = "10.1023/B:JRNC.0000028204.03708.89"
}

Đokić, D. Đ., Janković, D., Stamenkovic, L.,& Pirmettis, I.. (2004). Chemical and biological evaluation of Tc-99m (CO)(3) and Tc-99m complexes of some IDA derivatives. in Journal of Radioanalytical and Nuclear Chemistry, 260(3), 471-476.
https://doi.org/10.1023/B:JRNC.0000028204.03708.89

Đokić DĐ, Janković D, Stamenkovic L, Pirmettis I. Chemical and biological evaluation of Tc-99m (CO)(3) and Tc-99m complexes of some IDA derivatives. in Journal of Radioanalytical and Nuclear Chemistry. 2004;260(3):471-476.
doi:10.1023/B:JRNC.0000028204.03708.89 .

Đokić, Divna Đ., Janković, Drina, Stamenkovic, LL, Pirmettis, Ioannis, "Chemical and biological evaluation of Tc-99m (CO)(3) and Tc-99m complexes of some IDA derivatives" in Journal of Radioanalytical and Nuclear Chemistry, 260, no. 3 (2004):471-476,
https://doi.org/10.1023/B:JRNC.0000028204.03708.89 . .

TY  - JOUR
AU  - Đokić, Divna Đ.
AU  - Janković, Drina
AU  - Maksin, Tatjana N.
PY  - 2002
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2547
AB  - A new procedure for the aggregation of human albumin and Tc-99m-labelling of the prepared macroaggregated albumin are presented. Simple methods for quantifying of all the radiochemical impurities existing in Tc-99m-MAA were tested. Thus, 85% methanol was used as the mobile phase in paper and ITL chromatography with Whatman N-o 1 and ITLC-SA strips. A system of two solvents (acetone and 1 M NaCl or 0.9% NaCl) was used for 3 MM paper, ITLC-SA and ITLC-SG strips and silica gel plates as the stationary phase. Low-voltage paper electrophoresis with Whatman 3 MM paper sheets soaked in barbiturate buffer and the gel chromatography column method (Sephadex G-25) were also applied. Filtration through syringe filters, proposed by European and Yugoslav Pharmacopoeia, was performed for comparison. The application of the mentioned tests lead to consistent results for the labelling efficiency ( GT 98.5%) and percent radiochemical impurities of Tc-99m-MAA. Determination of the particles number in a counter chamber and their size distribution under a light microscope with a calibrated ocular scale gave the result of 300000-350000 particles per 1 mg of HA. This confirmed that the human albumin macroaggregates prepared by our new procedure is remarkably improved and convenient for routine diagnostic purposes.
T2  - Journal of the Serbian Chemical Society
T1  - Radiochemical purity and particles number determinations of modified Tc-99m-macroaggregated albumin
VL  - 67
IS  - 8-9
SP  - 573
EP  - 579
DO  - 10.2298/JSC0209573D
ER  - 

@article{
author = "Đokić, Divna Đ. and Janković, Drina and Maksin, Tatjana N.",
year = "2002",
abstract = "A new procedure for the aggregation of human albumin and Tc-99m-labelling of the prepared macroaggregated albumin are presented. Simple methods for quantifying of all the radiochemical impurities existing in Tc-99m-MAA were tested. Thus, 85% methanol was used as the mobile phase in paper and ITL chromatography with Whatman N-o 1 and ITLC-SA strips. A system of two solvents (acetone and 1 M NaCl or 0.9% NaCl) was used for 3 MM paper, ITLC-SA and ITLC-SG strips and silica gel plates as the stationary phase. Low-voltage paper electrophoresis with Whatman 3 MM paper sheets soaked in barbiturate buffer and the gel chromatography column method (Sephadex G-25) were also applied. Filtration through syringe filters, proposed by European and Yugoslav Pharmacopoeia, was performed for comparison. The application of the mentioned tests lead to consistent results for the labelling efficiency ( GT 98.5%) and percent radiochemical impurities of Tc-99m-MAA. Determination of the particles number in a counter chamber and their size distribution under a light microscope with a calibrated ocular scale gave the result of 300000-350000 particles per 1 mg of HA. This confirmed that the human albumin macroaggregates prepared by our new procedure is remarkably improved and convenient for routine diagnostic purposes.",
journal = "Journal of the Serbian Chemical Society",
title = "Radiochemical purity and particles number determinations of modified Tc-99m-macroaggregated albumin",
volume = "67",
number = "8-9",
pages = "573-579",
doi = "10.2298/JSC0209573D"
}

Đokić, D. Đ., Janković, D.,& Maksin, T. N.. (2002). Radiochemical purity and particles number determinations of modified Tc-99m-macroaggregated albumin. in Journal of the Serbian Chemical Society, 67(8-9), 573-579.
https://doi.org/10.2298/JSC0209573D

Đokić DĐ, Janković D, Maksin TN. Radiochemical purity and particles number determinations of modified Tc-99m-macroaggregated albumin. in Journal of the Serbian Chemical Society. 2002;67(8-9):573-579.
doi:10.2298/JSC0209573D .

Đokić, Divna Đ., Janković, Drina, Maksin, Tatjana N., "Radiochemical purity and particles number determinations of modified Tc-99m-macroaggregated albumin" in Journal of the Serbian Chemical Society, 67, no. 8-9 (2002):573-579,
https://doi.org/10.2298/JSC0209573D . .