Radojevic, Ivana D.

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orcid::0000-0002-1166-6137
  • Radojevic, Ivana D. (5)
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Author's Bibliography

DNA binding, antibacterial and antifungal activities of copper(II) complexes with some S-alkenyl derivatives of thiosalicylic acid

Tomović, Dušan Lj.; Bukonjić, Andriana M.; Jevtić, Verica V.; Ratković, Zoran R.; Bogojeski, Jovana V.; Đeković, Ana; Radojevic, Ivana D.; Čomić, Ljiljana R.; Novaković, Slađana B.; Bogdanović, Goran A.; Trifunović, Srećko R.; Radić, Gordana P.; Cupara, Snežana

(2018)

TY  - JOUR
AU  - Tomović, Dušan Lj.
AU  - Bukonjić, Andriana M.
AU  - Jevtić, Verica V.
AU  - Ratković, Zoran R.
AU  - Bogojeski, Jovana V.
AU  - Đeković, Ana
AU  - Radojevic, Ivana D.
AU  - Čomić, Ljiljana R.
AU  - Novaković, Slađana B.
AU  - Bogdanović, Goran A.
AU  - Trifunović, Srećko R.
AU  - Radić, Gordana P.
AU  - Cupara, Snežana
PY  - 2018
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/1954
AB  - The biological activities of two binuclear copper(II) complexes containing S-alkenyl derivatives of thiosalicylic acid are reported [alkenyl = propenyl (L1), isobutenyl (L2)]. The structure of the complex with the S-isobutenyl derivative (C2) was confirmed by single-crystal X-ray structure analysis, which revealed that the structure consists of centrosymmetric, dinuclear complex molecules [Cu-2(S-i-butenyl-thiosal)(4)(DMSO)(2)] containing two Cu(II) centers bridged by four S-isobutyl-thiosalicylate ligands in a paddle-wheel type structure. The Cu(II) atom is situated in a distorted square-pyramidal environment formed by carboxylate oxygen atoms in the basal plane and a DMSO ligand in the axial position. The reactivities of the complexes toward guanosine-5-monophosphate (5-GMP) were investigated. Complex C2 ([Cu-2(S-i-butenyl-thiosal)(4)(H2O)(2)]) reacted more rapidly with 5-GMP than complex C1. The interactions of complexes C1 and C2 with calf thymus DNA (CT-DNA) were examined by absorption (UV-Vis) and emission spectral studies (ethidium bromide displacement studies), revealing good DNA interaction abilities. The antimicrobial activities of the free ligands and their complexes were tested by microdilution method, and both minimal inhibitory and microbicidal concentrations were determined. All the tested substances demonstrated selective and moderate antibacterial activity on gram-positive bacteria, but low antibacterial activity on gram-negative bacteria. Also, the tested substances demonstrated low antifungal activity.
T2  - Transition Metal Chemistry
T1  - DNA binding, antibacterial and antifungal activities of copper(II) complexes with some S-alkenyl derivatives of thiosalicylic acid
VL  - 43
IS  - 2
SP  - 137
EP  - 148
DO  - 10.1007/s11243-018-0201-0
ER  - 
@article{
author = "Tomović, Dušan Lj. and Bukonjić, Andriana M. and Jevtić, Verica V. and Ratković, Zoran R. and Bogojeski, Jovana V. and Đeković, Ana and Radojevic, Ivana D. and Čomić, Ljiljana R. and Novaković, Slađana B. and Bogdanović, Goran A. and Trifunović, Srećko R. and Radić, Gordana P. and Cupara, Snežana",
year = "2018",
abstract = "The biological activities of two binuclear copper(II) complexes containing S-alkenyl derivatives of thiosalicylic acid are reported [alkenyl = propenyl (L1), isobutenyl (L2)]. The structure of the complex with the S-isobutenyl derivative (C2) was confirmed by single-crystal X-ray structure analysis, which revealed that the structure consists of centrosymmetric, dinuclear complex molecules [Cu-2(S-i-butenyl-thiosal)(4)(DMSO)(2)] containing two Cu(II) centers bridged by four S-isobutyl-thiosalicylate ligands in a paddle-wheel type structure. The Cu(II) atom is situated in a distorted square-pyramidal environment formed by carboxylate oxygen atoms in the basal plane and a DMSO ligand in the axial position. The reactivities of the complexes toward guanosine-5-monophosphate (5-GMP) were investigated. Complex C2 ([Cu-2(S-i-butenyl-thiosal)(4)(H2O)(2)]) reacted more rapidly with 5-GMP than complex C1. The interactions of complexes C1 and C2 with calf thymus DNA (CT-DNA) were examined by absorption (UV-Vis) and emission spectral studies (ethidium bromide displacement studies), revealing good DNA interaction abilities. The antimicrobial activities of the free ligands and their complexes were tested by microdilution method, and both minimal inhibitory and microbicidal concentrations were determined. All the tested substances demonstrated selective and moderate antibacterial activity on gram-positive bacteria, but low antibacterial activity on gram-negative bacteria. Also, the tested substances demonstrated low antifungal activity.",
journal = "Transition Metal Chemistry",
title = "DNA binding, antibacterial and antifungal activities of copper(II) complexes with some S-alkenyl derivatives of thiosalicylic acid",
volume = "43",
number = "2",
pages = "137-148",
doi = "10.1007/s11243-018-0201-0"
}
Tomović, D. Lj., Bukonjić, A. M., Jevtić, V. V., Ratković, Z. R., Bogojeski, J. V., Đeković, A., Radojevic, I. D., Čomić, L. R., Novaković, S. B., Bogdanović, G. A., Trifunović, S. R., Radić, G. P.,& Cupara, S.. (2018). DNA binding, antibacterial and antifungal activities of copper(II) complexes with some S-alkenyl derivatives of thiosalicylic acid. in Transition Metal Chemistry, 43(2), 137-148.
https://doi.org/10.1007/s11243-018-0201-0
Tomović DL, Bukonjić AM, Jevtić VV, Ratković ZR, Bogojeski JV, Đeković A, Radojevic ID, Čomić LR, Novaković SB, Bogdanović GA, Trifunović SR, Radić GP, Cupara S. DNA binding, antibacterial and antifungal activities of copper(II) complexes with some S-alkenyl derivatives of thiosalicylic acid. in Transition Metal Chemistry. 2018;43(2):137-148.
doi:10.1007/s11243-018-0201-0 .
Tomović, Dušan Lj., Bukonjić, Andriana M., Jevtić, Verica V., Ratković, Zoran R., Bogojeski, Jovana V., Đeković, Ana, Radojevic, Ivana D., Čomić, Ljiljana R., Novaković, Slađana B., Bogdanović, Goran A., Trifunović, Srećko R., Radić, Gordana P., Cupara, Snežana, "DNA binding, antibacterial and antifungal activities of copper(II) complexes with some S-alkenyl derivatives of thiosalicylic acid" in Transition Metal Chemistry, 43, no. 2 (2018):137-148,
https://doi.org/10.1007/s11243-018-0201-0 . .
7
3
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Antibacterial, antibiofilm and antioxidant screening of copper(II)-complexes with some S-alkyl derivatives of thiosalicylic acid. Crystal structure of the binuclear copper(II)-complex with S-propyl derivative of thiosalicylic acid

Bukonjić, Andriana M.; Tomović, Dušan Lj.; Nikolić, Miloš V.; Mijajlović, Marina Ž.; Jevtić, Verica V.; Ratković, Zoran R.; Novaković, Slađana B.; Bogdanović, Goran A.; Radojevic, Ivana D.; Maksimović, Jovana Z.; Vasić, Sava M.; Čomić, Ljiljana R.; Trifunović, Srećko R.; Radić, Gordana P.

(2017)

TY  - JOUR
AU  - Bukonjić, Andriana M.
AU  - Tomović, Dušan Lj.
AU  - Nikolić, Miloš V.
AU  - Mijajlović, Marina Ž.
AU  - Jevtić, Verica V.
AU  - Ratković, Zoran R.
AU  - Novaković, Slađana B.
AU  - Bogdanović, Goran A.
AU  - Radojevic, Ivana D.
AU  - Maksimović, Jovana Z.
AU  - Vasić, Sava M.
AU  - Čomić, Ljiljana R.
AU  - Trifunović, Srećko R.
AU  - Radić, Gordana P.
PY  - 2017
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/1296
AB  - The spectroscopically predicted structure of the obtained copper(II)-complex with S-propyl derivative of thiosalicylic acid was confirmed by X-ray structural study. The binuclear copper(II)-complex with S-propyl derivative of thiosalicylic acid crystallized in two polymorphic forms with main structural difference in the orientation of phenyl rings relative to corresponding carboxylate groups. The antibacterial activity was tested determining the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) by using microdilution method. The influence on bacterial biofilm formation was determined by tissue culture plate method. In general, the copper(II)-complexes manifested a selective and moderate activity. The most sensitive bacteria to the effects of Cu(II)-complexes was a clinical isolate of Pseudomonas aeruginosa. For this bacteria MIC and biofilm inhibitory concentration (BIC) values for all tested complexes were in the range or better than the positive control, doxycycline. Also, for the established biofilm of clinical isolate Staphylococcus aureus, BIC values for the copper(II)-complex with S-ethyl derivative of thiosalicylic acid, [Cu-2(S-et-thiosal)(4)(H2O)(2)] (C3) and copper(II)-complex with S-butyl derivative of thiosalicylic acid, [Cu-2(S-bu-thiosal)(4)(H2O)(2)] (C5) were in range or better than the positive control. All the complexes acted better against Gram-positive bacteria (Staphylococcus aureus and Staphylococcus aureus ATCC 25923) than Gram-negative bacteria (Proteus mirabilis ATCC 12453, Pseudomonas aeruginosa, and P. aeruginosa. ATCC 27855). The complexes showed weak antioxidative properties tested by two methods (1,1-diphenyl-2-picrylhydrazyl (DPPH) and reducing power assay). (C) 2016 Elsevier B.V. All rights reserved.
T2  - Journal of Molecular Structure
T1  - Antibacterial, antibiofilm and antioxidant screening of copper(II)-complexes with some S-alkyl derivatives of thiosalicylic acid. Crystal structure of the binuclear copper(II)-complex with S-propyl derivative of thiosalicylic acid
VL  - 1128
SP  - 330
EP  - 337
DO  - 10.1016/j.molstruc.2016.08.086
ER  - 
@article{
author = "Bukonjić, Andriana M. and Tomović, Dušan Lj. and Nikolić, Miloš V. and Mijajlović, Marina Ž. and Jevtić, Verica V. and Ratković, Zoran R. and Novaković, Slađana B. and Bogdanović, Goran A. and Radojevic, Ivana D. and Maksimović, Jovana Z. and Vasić, Sava M. and Čomić, Ljiljana R. and Trifunović, Srećko R. and Radić, Gordana P.",
year = "2017",
abstract = "The spectroscopically predicted structure of the obtained copper(II)-complex with S-propyl derivative of thiosalicylic acid was confirmed by X-ray structural study. The binuclear copper(II)-complex with S-propyl derivative of thiosalicylic acid crystallized in two polymorphic forms with main structural difference in the orientation of phenyl rings relative to corresponding carboxylate groups. The antibacterial activity was tested determining the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) by using microdilution method. The influence on bacterial biofilm formation was determined by tissue culture plate method. In general, the copper(II)-complexes manifested a selective and moderate activity. The most sensitive bacteria to the effects of Cu(II)-complexes was a clinical isolate of Pseudomonas aeruginosa. For this bacteria MIC and biofilm inhibitory concentration (BIC) values for all tested complexes were in the range or better than the positive control, doxycycline. Also, for the established biofilm of clinical isolate Staphylococcus aureus, BIC values for the copper(II)-complex with S-ethyl derivative of thiosalicylic acid, [Cu-2(S-et-thiosal)(4)(H2O)(2)] (C3) and copper(II)-complex with S-butyl derivative of thiosalicylic acid, [Cu-2(S-bu-thiosal)(4)(H2O)(2)] (C5) were in range or better than the positive control. All the complexes acted better against Gram-positive bacteria (Staphylococcus aureus and Staphylococcus aureus ATCC 25923) than Gram-negative bacteria (Proteus mirabilis ATCC 12453, Pseudomonas aeruginosa, and P. aeruginosa. ATCC 27855). The complexes showed weak antioxidative properties tested by two methods (1,1-diphenyl-2-picrylhydrazyl (DPPH) and reducing power assay). (C) 2016 Elsevier B.V. All rights reserved.",
journal = "Journal of Molecular Structure",
title = "Antibacterial, antibiofilm and antioxidant screening of copper(II)-complexes with some S-alkyl derivatives of thiosalicylic acid. Crystal structure of the binuclear copper(II)-complex with S-propyl derivative of thiosalicylic acid",
volume = "1128",
pages = "330-337",
doi = "10.1016/j.molstruc.2016.08.086"
}
Bukonjić, A. M., Tomović, D. Lj., Nikolić, M. V., Mijajlović, M. Ž., Jevtić, V. V., Ratković, Z. R., Novaković, S. B., Bogdanović, G. A., Radojevic, I. D., Maksimović, J. Z., Vasić, S. M., Čomić, L. R., Trifunović, S. R.,& Radić, G. P.. (2017). Antibacterial, antibiofilm and antioxidant screening of copper(II)-complexes with some S-alkyl derivatives of thiosalicylic acid. Crystal structure of the binuclear copper(II)-complex with S-propyl derivative of thiosalicylic acid. in Journal of Molecular Structure, 1128, 330-337.
https://doi.org/10.1016/j.molstruc.2016.08.086
Bukonjić AM, Tomović DL, Nikolić MV, Mijajlović MŽ, Jevtić VV, Ratković ZR, Novaković SB, Bogdanović GA, Radojevic ID, Maksimović JZ, Vasić SM, Čomić LR, Trifunović SR, Radić GP. Antibacterial, antibiofilm and antioxidant screening of copper(II)-complexes with some S-alkyl derivatives of thiosalicylic acid. Crystal structure of the binuclear copper(II)-complex with S-propyl derivative of thiosalicylic acid. in Journal of Molecular Structure. 2017;1128:330-337.
doi:10.1016/j.molstruc.2016.08.086 .
Bukonjić, Andriana M., Tomović, Dušan Lj., Nikolić, Miloš V., Mijajlović, Marina Ž., Jevtić, Verica V., Ratković, Zoran R., Novaković, Slađana B., Bogdanović, Goran A., Radojevic, Ivana D., Maksimović, Jovana Z., Vasić, Sava M., Čomić, Ljiljana R., Trifunović, Srećko R., Radić, Gordana P., "Antibacterial, antibiofilm and antioxidant screening of copper(II)-complexes with some S-alkyl derivatives of thiosalicylic acid. Crystal structure of the binuclear copper(II)-complex with S-propyl derivative of thiosalicylic acid" in Journal of Molecular Structure, 1128 (2017):330-337,
https://doi.org/10.1016/j.molstruc.2016.08.086 . .
19
15
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Stereospecific ligands and their complexes. Part XXI. Synthesis, characterization, circular dichroism and antimicrobial activity of cobalt(III) complexes with some edda-type of ligands. Crystal structure of potassium-Delta-(-)(589)-s-cis-oxalato-(S,S)-ethylenediamine-N,N -di-(2-propanoato)-cobaltate(III)-semihydrate, K-Delta-(-)(589)-s-cis-[Co(S,S-eddp)(ox)]center dot 0.5H(2)O

Ilić, Dragoslav; Jevtić, Verica V.; Vasojevic, Miorad M.; Jelic, Miodrag Z.; Radojevic, Ivana D.; Čomić, Ljiljana R.; Novaković, Slađana B.; Bogdanović, Goran A.; Potocnak, Ivan; Trifunović, Srećko R.

(2015)

TY  - JOUR
AU  - Ilić, Dragoslav
AU  - Jevtić, Verica V.
AU  - Vasojevic, Miorad M.
AU  - Jelic, Miodrag Z.
AU  - Radojevic, Ivana D.
AU  - Čomić, Ljiljana R.
AU  - Novaković, Slađana B.
AU  - Bogdanović, Goran A.
AU  - Potocnak, Ivan
AU  - Trifunović, Srećko R.
PY  - 2015
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/342
AB  - The octahedral cobalt(III) complexes with (S,S)-ethylenediamine-N,N-di-2-propionic (S,S-eddp) and (S,S)-ethylenediamine-N,N-di-2-(3-methyl)-butanoic (S,S-eddv) acids and oxalato and malonato ligands, as additional bidentate ligands, were prepared and characterized. The complexes were purified by ionexchange chromatography. The geometry of the complexes has been supposed on the basis of the infrared, electronic absorption and NMR spectra. The A absolute configurations of the isolated complexes have been predicted on the basis of their circular dichroism (CD) spectra and it was confirmed by single-crystal X-ray analysis of potassium-Delta-(-)(589)-s-cis-oxalato-(S,S)-ethylenediamine-N,N-di-(2-propanoato)-cobaltate(III)-semihydrate, K-Delta-(-)(589)-s-cis-[Co(S,S-eddp)(ox)]center dot 0.5H(2)O. Antimicrobial activity of ligands and obtained cobalt(III) complexes was evaluated by determining the minimum inhibitory concentration (MIC) and minimum microbicidal concentration (MMC) in relation to 13 species of microorganisms (five strains of pathogenic bacteria, five species pathogenic fungi and three species of probiotic). Tested ligands and complexes demonstrated moderate and low antibacterial and antifungal activity. There was no difference in activities between the ligands and complexes. (C) 2014 Elsevier Ltd. All rights reserved.
T2  - Polyhedron
T1  - Stereospecific ligands and their complexes. Part XXI. Synthesis, characterization, circular dichroism and antimicrobial activity of cobalt(III) complexes with some edda-type of ligands. Crystal structure of potassium-Delta-(-)(589)-s-cis-oxalato-(S,S)-ethylenediamine-N,N -di-(2-propanoato)-cobaltate(III)-semihydrate, K-Delta-(-)(589)-s-cis-[Co(S,S-eddp)(ox)]center dot 0.5H(2)O
VL  - 85
SP  - 1
EP  - 9
DO  - 10.1016/j.poly.2014.08.013
ER  - 
@article{
author = "Ilić, Dragoslav and Jevtić, Verica V. and Vasojevic, Miorad M. and Jelic, Miodrag Z. and Radojevic, Ivana D. and Čomić, Ljiljana R. and Novaković, Slađana B. and Bogdanović, Goran A. and Potocnak, Ivan and Trifunović, Srećko R.",
year = "2015",
abstract = "The octahedral cobalt(III) complexes with (S,S)-ethylenediamine-N,N-di-2-propionic (S,S-eddp) and (S,S)-ethylenediamine-N,N-di-2-(3-methyl)-butanoic (S,S-eddv) acids and oxalato and malonato ligands, as additional bidentate ligands, were prepared and characterized. The complexes were purified by ionexchange chromatography. The geometry of the complexes has been supposed on the basis of the infrared, electronic absorption and NMR spectra. The A absolute configurations of the isolated complexes have been predicted on the basis of their circular dichroism (CD) spectra and it was confirmed by single-crystal X-ray analysis of potassium-Delta-(-)(589)-s-cis-oxalato-(S,S)-ethylenediamine-N,N-di-(2-propanoato)-cobaltate(III)-semihydrate, K-Delta-(-)(589)-s-cis-[Co(S,S-eddp)(ox)]center dot 0.5H(2)O. Antimicrobial activity of ligands and obtained cobalt(III) complexes was evaluated by determining the minimum inhibitory concentration (MIC) and minimum microbicidal concentration (MMC) in relation to 13 species of microorganisms (five strains of pathogenic bacteria, five species pathogenic fungi and three species of probiotic). Tested ligands and complexes demonstrated moderate and low antibacterial and antifungal activity. There was no difference in activities between the ligands and complexes. (C) 2014 Elsevier Ltd. All rights reserved.",
journal = "Polyhedron",
title = "Stereospecific ligands and their complexes. Part XXI. Synthesis, characterization, circular dichroism and antimicrobial activity of cobalt(III) complexes with some edda-type of ligands. Crystal structure of potassium-Delta-(-)(589)-s-cis-oxalato-(S,S)-ethylenediamine-N,N -di-(2-propanoato)-cobaltate(III)-semihydrate, K-Delta-(-)(589)-s-cis-[Co(S,S-eddp)(ox)]center dot 0.5H(2)O",
volume = "85",
pages = "1-9",
doi = "10.1016/j.poly.2014.08.013"
}
Ilić, D., Jevtić, V. V., Vasojevic, M. M., Jelic, M. Z., Radojevic, I. D., Čomić, L. R., Novaković, S. B., Bogdanović, G. A., Potocnak, I.,& Trifunović, S. R.. (2015). Stereospecific ligands and their complexes. Part XXI. Synthesis, characterization, circular dichroism and antimicrobial activity of cobalt(III) complexes with some edda-type of ligands. Crystal structure of potassium-Delta-(-)(589)-s-cis-oxalato-(S,S)-ethylenediamine-N,N -di-(2-propanoato)-cobaltate(III)-semihydrate, K-Delta-(-)(589)-s-cis-[Co(S,S-eddp)(ox)]center dot 0.5H(2)O. in Polyhedron, 85, 1-9.
https://doi.org/10.1016/j.poly.2014.08.013
Ilić D, Jevtić VV, Vasojevic MM, Jelic MZ, Radojevic ID, Čomić LR, Novaković SB, Bogdanović GA, Potocnak I, Trifunović SR. Stereospecific ligands and their complexes. Part XXI. Synthesis, characterization, circular dichroism and antimicrobial activity of cobalt(III) complexes with some edda-type of ligands. Crystal structure of potassium-Delta-(-)(589)-s-cis-oxalato-(S,S)-ethylenediamine-N,N -di-(2-propanoato)-cobaltate(III)-semihydrate, K-Delta-(-)(589)-s-cis-[Co(S,S-eddp)(ox)]center dot 0.5H(2)O. in Polyhedron. 2015;85:1-9.
doi:10.1016/j.poly.2014.08.013 .
Ilić, Dragoslav, Jevtić, Verica V., Vasojevic, Miorad M., Jelic, Miodrag Z., Radojevic, Ivana D., Čomić, Ljiljana R., Novaković, Slađana B., Bogdanović, Goran A., Potocnak, Ivan, Trifunović, Srećko R., "Stereospecific ligands and their complexes. Part XXI. Synthesis, characterization, circular dichroism and antimicrobial activity of cobalt(III) complexes with some edda-type of ligands. Crystal structure of potassium-Delta-(-)(589)-s-cis-oxalato-(S,S)-ethylenediamine-N,N -di-(2-propanoato)-cobaltate(III)-semihydrate, K-Delta-(-)(589)-s-cis-[Co(S,S-eddp)(ox)]center dot 0.5H(2)O" in Polyhedron, 85 (2015):1-9,
https://doi.org/10.1016/j.poly.2014.08.013 . .
1
1
1

Synthesis, characterization and antimicrobial activity of copper(II) complexes with some S-alkyl derivatives of thiosalicylic acid. Crystal structure of the binuclear copper(II) complex with S-methyl derivative of thiosalicylic acid

Nikolić, Miloš V.; Mijajlović, Marina Ž.; Jevtić, Verica V.; Ratković, Zoran R.; Radojevic, Ivana D.; Čomić, Ljiljana R.; Novaković, Slađana B.; Bogdanović, Goran A.; Trifunović, Srećko R.; Radić, Gordana P.

(2014)

TY  - JOUR
AU  - Nikolić, Miloš V.
AU  - Mijajlović, Marina Ž.
AU  - Jevtić, Verica V.
AU  - Ratković, Zoran R.
AU  - Radojevic, Ivana D.
AU  - Čomić, Ljiljana R.
AU  - Novaković, Slađana B.
AU  - Bogdanović, Goran A.
AU  - Trifunović, Srećko R.
AU  - Radić, Gordana P.
PY  - 2014
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/106
AB  - The five new copper(II) complexes with some S-alkyl derivatives of thiosalicylic acid (alkyl = benzyl (L1), methyl (L2), ethyl (L3), propyl (L4), butyl (L5)) have been synthesized and characterized by microanalysis and infrared spectra. The spectroscopically predicted structure of the obtained binuclear copper(II) complex with S-methyl derivative of thiosalicylic acid was confirmed by X-ray analysis. Single crystals suitable for X-ray measurements were obtained by slow crystallization from a water solution. The compound crystallizes with two binuclear Cu(II) complex molecules in the asymmetric unit. Both molecules have typical paddle-wheel structure with apical positions occupied by water molecules. The independent molecules showed slight difference in configuration mainly reflected in the different orientation of the phenyl rings relating to their carboxylate groups. Antimicrobial activity of these complexes was tested by microdilution method and both minimal inhibitory and microbicidal concentration were determined. The intensity of the antimicrobial activity varied depending on the species of microorganism and the compound type. In general, the activity of the complexes was higher than or similar to the corresponding ligands. All the tested complexes demonstrated moderate or selective antibacterial activity and low antifungal activity. (C) 2014 Elsevier Ltd. All rights reserved.
T2  - Polyhedron
T1  - Synthesis, characterization and antimicrobial activity of copper(II) complexes with some S-alkyl derivatives of thiosalicylic acid. Crystal structure of the binuclear copper(II) complex with S-methyl derivative of thiosalicylic acid
VL  - 79
SP  - 80
EP  - 87
DO  - 10.1016/j.poly.2014.04.053
ER  - 
@article{
author = "Nikolić, Miloš V. and Mijajlović, Marina Ž. and Jevtić, Verica V. and Ratković, Zoran R. and Radojevic, Ivana D. and Čomić, Ljiljana R. and Novaković, Slađana B. and Bogdanović, Goran A. and Trifunović, Srećko R. and Radić, Gordana P.",
year = "2014",
abstract = "The five new copper(II) complexes with some S-alkyl derivatives of thiosalicylic acid (alkyl = benzyl (L1), methyl (L2), ethyl (L3), propyl (L4), butyl (L5)) have been synthesized and characterized by microanalysis and infrared spectra. The spectroscopically predicted structure of the obtained binuclear copper(II) complex with S-methyl derivative of thiosalicylic acid was confirmed by X-ray analysis. Single crystals suitable for X-ray measurements were obtained by slow crystallization from a water solution. The compound crystallizes with two binuclear Cu(II) complex molecules in the asymmetric unit. Both molecules have typical paddle-wheel structure with apical positions occupied by water molecules. The independent molecules showed slight difference in configuration mainly reflected in the different orientation of the phenyl rings relating to their carboxylate groups. Antimicrobial activity of these complexes was tested by microdilution method and both minimal inhibitory and microbicidal concentration were determined. The intensity of the antimicrobial activity varied depending on the species of microorganism and the compound type. In general, the activity of the complexes was higher than or similar to the corresponding ligands. All the tested complexes demonstrated moderate or selective antibacterial activity and low antifungal activity. (C) 2014 Elsevier Ltd. All rights reserved.",
journal = "Polyhedron",
title = "Synthesis, characterization and antimicrobial activity of copper(II) complexes with some S-alkyl derivatives of thiosalicylic acid. Crystal structure of the binuclear copper(II) complex with S-methyl derivative of thiosalicylic acid",
volume = "79",
pages = "80-87",
doi = "10.1016/j.poly.2014.04.053"
}
Nikolić, M. V., Mijajlović, M. Ž., Jevtić, V. V., Ratković, Z. R., Radojevic, I. D., Čomić, L. R., Novaković, S. B., Bogdanović, G. A., Trifunović, S. R.,& Radić, G. P.. (2014). Synthesis, characterization and antimicrobial activity of copper(II) complexes with some S-alkyl derivatives of thiosalicylic acid. Crystal structure of the binuclear copper(II) complex with S-methyl derivative of thiosalicylic acid. in Polyhedron, 79, 80-87.
https://doi.org/10.1016/j.poly.2014.04.053
Nikolić MV, Mijajlović MŽ, Jevtić VV, Ratković ZR, Radojevic ID, Čomić LR, Novaković SB, Bogdanović GA, Trifunović SR, Radić GP. Synthesis, characterization and antimicrobial activity of copper(II) complexes with some S-alkyl derivatives of thiosalicylic acid. Crystal structure of the binuclear copper(II) complex with S-methyl derivative of thiosalicylic acid. in Polyhedron. 2014;79:80-87.
doi:10.1016/j.poly.2014.04.053 .
Nikolić, Miloš V., Mijajlović, Marina Ž., Jevtić, Verica V., Ratković, Zoran R., Radojevic, Ivana D., Čomić, Ljiljana R., Novaković, Slađana B., Bogdanović, Goran A., Trifunović, Srećko R., Radić, Gordana P., "Synthesis, characterization and antimicrobial activity of copper(II) complexes with some S-alkyl derivatives of thiosalicylic acid. Crystal structure of the binuclear copper(II) complex with S-methyl derivative of thiosalicylic acid" in Polyhedron, 79 (2014):80-87,
https://doi.org/10.1016/j.poly.2014.04.053 . .
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Synthesis, characterization and antimicrobial activity of novel platinum(IV) and palladium(II) complexes with meso-1,2-diphenyl-ethylenediamine-N,N -di-3-propanoic acid - Crystal structure of H-2-1,2-dpheddp center dot 2HCl center dot H2O

Radić, Gordana P.; Glodovic, Verica V.; Ratković, Zoran R.; Novaković, Slađana B.; Garcia-Granda, Santiago; Roces, Laura; Menendez-Taboada, Laura; Radojevic, Ivana D.; Stefanovic, Olgica D.; Čomić, Ljiljana R.; Trifunović, Srećko R.

(2012)

TY  - JOUR
AU  - Radić, Gordana P.
AU  - Glodovic, Verica V.
AU  - Ratković, Zoran R.
AU  - Novaković, Slađana B.
AU  - Garcia-Granda, Santiago
AU  - Roces, Laura
AU  - Menendez-Taboada, Laura
AU  - Radojevic, Ivana D.
AU  - Stefanovic, Olgica D.
AU  - Čomić, Ljiljana R.
AU  - Trifunović, Srećko R.
PY  - 2012
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/5197
AB  - In the reaction of meso-1,2-diphenyl-ethylenediamine (1,2-dphen) with neutralized 3-chlor-propanoic acid, the new linear tetradentate edda-like ligand (edda = ethylenediamine-N,N-diacetic ion) meso-1, 2-diphenyl-ethylenediamine-N,N-di-3-propanoic acid dihydrochloride monohydrate (H-2-1,2-dpheddp center dot 2HCl center dot H2O) was prepared. The corresponding platinum(IV) complex, s-cis-dichlorido-(meso-1,2-diphenyl-ethylenediamine-N,N-di-3-propanoate)-platinum(IV) ([PtCl2(1,2-dpheddp)]) was synthesized by heating potassium-hexachloridoplatinate(IV) and H-2-1,2-dpheddp center dot 2HCl center dot H2O on steam bath for 12 h with neutralization by means of lithium-hydroxide. The palladium(II) complex, cis-dichlorido-(meso-1,2diphenyl-ethylenediamine-N,N-di-3-propanoate)-palladium(II) (IPdCl2(1,2-dpheddp)]) was obtained in the similar way using potassium-tetrachloridopalladate(II), H-2-1,2-dpheddp-2HCl center dot H2O and lithium-hydroxide. The compounds were characterized by elemental analysis and infrared spectroscopy. The spectroscopically predicted structure of the synthesized tetradentate ligand was confirmed by X-ray analysis of the H-2-1,2-dpheddp.2HCl center dot H2O. Antimicrobial activity of the ligand and corresponding palladium(II) and platinum(IV) complexes is investigated against 25 species of microorganisms. Testing is preformed by microdilution method and minimum inhibitory concentrations (MIC) and minimum microbicidal concentration (MMC) have been determined. The difference between antimicrobial activity of the ligand and corresponding platinum(IV) and palladium(II) complex is noticed and, in general, palladium(II) complex was the most active. (C) 2012 Elsevier B.V. All rights reserved.
T2  - Journal of Molecular Structure
T1  - Synthesis, characterization and antimicrobial activity of novel platinum(IV) and palladium(II) complexes with meso-1,2-diphenyl-ethylenediamine-N,N -di-3-propanoic acid - Crystal structure of H-2-1,2-dpheddp center dot 2HCl center dot H2O
VL  - 1029
SP  - 180
EP  - 186
DO  - 10.1016/j.molstruc.2012.07.007
ER  - 
@article{
author = "Radić, Gordana P. and Glodovic, Verica V. and Ratković, Zoran R. and Novaković, Slađana B. and Garcia-Granda, Santiago and Roces, Laura and Menendez-Taboada, Laura and Radojevic, Ivana D. and Stefanovic, Olgica D. and Čomić, Ljiljana R. and Trifunović, Srećko R.",
year = "2012",
abstract = "In the reaction of meso-1,2-diphenyl-ethylenediamine (1,2-dphen) with neutralized 3-chlor-propanoic acid, the new linear tetradentate edda-like ligand (edda = ethylenediamine-N,N-diacetic ion) meso-1, 2-diphenyl-ethylenediamine-N,N-di-3-propanoic acid dihydrochloride monohydrate (H-2-1,2-dpheddp center dot 2HCl center dot H2O) was prepared. The corresponding platinum(IV) complex, s-cis-dichlorido-(meso-1,2-diphenyl-ethylenediamine-N,N-di-3-propanoate)-platinum(IV) ([PtCl2(1,2-dpheddp)]) was synthesized by heating potassium-hexachloridoplatinate(IV) and H-2-1,2-dpheddp center dot 2HCl center dot H2O on steam bath for 12 h with neutralization by means of lithium-hydroxide. The palladium(II) complex, cis-dichlorido-(meso-1,2diphenyl-ethylenediamine-N,N-di-3-propanoate)-palladium(II) (IPdCl2(1,2-dpheddp)]) was obtained in the similar way using potassium-tetrachloridopalladate(II), H-2-1,2-dpheddp-2HCl center dot H2O and lithium-hydroxide. The compounds were characterized by elemental analysis and infrared spectroscopy. The spectroscopically predicted structure of the synthesized tetradentate ligand was confirmed by X-ray analysis of the H-2-1,2-dpheddp.2HCl center dot H2O. Antimicrobial activity of the ligand and corresponding palladium(II) and platinum(IV) complexes is investigated against 25 species of microorganisms. Testing is preformed by microdilution method and minimum inhibitory concentrations (MIC) and minimum microbicidal concentration (MMC) have been determined. The difference between antimicrobial activity of the ligand and corresponding platinum(IV) and palladium(II) complex is noticed and, in general, palladium(II) complex was the most active. (C) 2012 Elsevier B.V. All rights reserved.",
journal = "Journal of Molecular Structure",
title = "Synthesis, characterization and antimicrobial activity of novel platinum(IV) and palladium(II) complexes with meso-1,2-diphenyl-ethylenediamine-N,N -di-3-propanoic acid - Crystal structure of H-2-1,2-dpheddp center dot 2HCl center dot H2O",
volume = "1029",
pages = "180-186",
doi = "10.1016/j.molstruc.2012.07.007"
}
Radić, G. P., Glodovic, V. V., Ratković, Z. R., Novaković, S. B., Garcia-Granda, S., Roces, L., Menendez-Taboada, L., Radojevic, I. D., Stefanovic, O. D., Čomić, L. R.,& Trifunović, S. R.. (2012). Synthesis, characterization and antimicrobial activity of novel platinum(IV) and palladium(II) complexes with meso-1,2-diphenyl-ethylenediamine-N,N -di-3-propanoic acid - Crystal structure of H-2-1,2-dpheddp center dot 2HCl center dot H2O. in Journal of Molecular Structure, 1029, 180-186.
https://doi.org/10.1016/j.molstruc.2012.07.007
Radić GP, Glodovic VV, Ratković ZR, Novaković SB, Garcia-Granda S, Roces L, Menendez-Taboada L, Radojevic ID, Stefanovic OD, Čomić LR, Trifunović SR. Synthesis, characterization and antimicrobial activity of novel platinum(IV) and palladium(II) complexes with meso-1,2-diphenyl-ethylenediamine-N,N -di-3-propanoic acid - Crystal structure of H-2-1,2-dpheddp center dot 2HCl center dot H2O. in Journal of Molecular Structure. 2012;1029:180-186.
doi:10.1016/j.molstruc.2012.07.007 .
Radić, Gordana P., Glodovic, Verica V., Ratković, Zoran R., Novaković, Slađana B., Garcia-Granda, Santiago, Roces, Laura, Menendez-Taboada, Laura, Radojevic, Ivana D., Stefanovic, Olgica D., Čomić, Ljiljana R., Trifunović, Srećko R., "Synthesis, characterization and antimicrobial activity of novel platinum(IV) and palladium(II) complexes with meso-1,2-diphenyl-ethylenediamine-N,N -di-3-propanoic acid - Crystal structure of H-2-1,2-dpheddp center dot 2HCl center dot H2O" in Journal of Molecular Structure, 1029 (2012):180-186,
https://doi.org/10.1016/j.molstruc.2012.07.007 . .
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