TY  - JOUR
AU  - Vladisavljević, Goran T.
AU  - Wang, Bing
AU  - Dragosavac, Marijana M.
AU  - Holdich, Richard G.
PY  - 2014
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/7010
AB  - Food-grade water-in-oil-in-water (W/O/W) multiple emulsions with a volume median diameter of outer droplets of 50-210 mu m were produced by injecting a water-in-oil (W/O) emulsion at the flux of 30 L m(-2) h(-1) through a 10-mu m pore electroplated nickel membrane oscillating at 10-90 Hz frequency and 0.1-5 mm amplitude in 2 wt% aqueous Tween(R) 20 (polyoxyethylene sorbitan monolaurate) solution. The oil phase in the primary W/O emulsion was 5 wt% PGPR (polyglycerol polyricinoleate) dissolved in sunflower oil and the content of water phase in the W/O emulsion was 30 vol%. The size of outer droplets was precisely controlled by the amplitude and frequency of membrane oscillation. Only 3-5% of the inner droplets with a mean diameter of 0.54 mu m were released into the outer aqueous phase during membrane emulsification. A sustained release of 200 ppm copper (II) loaded in the inner aqueous phase was investigated over 7 days. 95% of Cu(II) initially present in the inner water phase was released in the first 2 days from 56-mu m diameter multiple emulsion droplets and less than 15% of Cu(II) was released over the same interval from 122 mu m droplets. The release rate of Cu(II) decreased with increasing the size of outer droplets and followed non-zero-order kinetics with a release exponent of 0.3-0.5. The prepared multiple emulsions can be used for controlled release of hydrophilic actives in the pharmaceutical, food, and cosmetic industry. (C) 2014 Elsevier B.V. All rights reserved.
T2  - Colloids and Surfaces. A: Physicochemical and Engineering Aspects
T1  - Production of food-grade multiple emulsions with high encapsulation yield using oscillating membrane emulsification
VL  - 458
SP  - 78
EP  - 84
DO  - 10.1016/j.colsurfa.2014.05.011
ER  - 

@article{
author = "Vladisavljević, Goran T. and Wang, Bing and Dragosavac, Marijana M. and Holdich, Richard G.",
year = "2014",
abstract = "Food-grade water-in-oil-in-water (W/O/W) multiple emulsions with a volume median diameter of outer droplets of 50-210 mu m were produced by injecting a water-in-oil (W/O) emulsion at the flux of 30 L m(-2) h(-1) through a 10-mu m pore electroplated nickel membrane oscillating at 10-90 Hz frequency and 0.1-5 mm amplitude in 2 wt% aqueous Tween(R) 20 (polyoxyethylene sorbitan monolaurate) solution. The oil phase in the primary W/O emulsion was 5 wt% PGPR (polyglycerol polyricinoleate) dissolved in sunflower oil and the content of water phase in the W/O emulsion was 30 vol%. The size of outer droplets was precisely controlled by the amplitude and frequency of membrane oscillation. Only 3-5% of the inner droplets with a mean diameter of 0.54 mu m were released into the outer aqueous phase during membrane emulsification. A sustained release of 200 ppm copper (II) loaded in the inner aqueous phase was investigated over 7 days. 95% of Cu(II) initially present in the inner water phase was released in the first 2 days from 56-mu m diameter multiple emulsion droplets and less than 15% of Cu(II) was released over the same interval from 122 mu m droplets. The release rate of Cu(II) decreased with increasing the size of outer droplets and followed non-zero-order kinetics with a release exponent of 0.3-0.5. The prepared multiple emulsions can be used for controlled release of hydrophilic actives in the pharmaceutical, food, and cosmetic industry. (C) 2014 Elsevier B.V. All rights reserved.",
journal = "Colloids and Surfaces. A: Physicochemical and Engineering Aspects",
title = "Production of food-grade multiple emulsions with high encapsulation yield using oscillating membrane emulsification",
volume = "458",
pages = "78-84",
doi = "10.1016/j.colsurfa.2014.05.011"
}

Vladisavljević, G. T., Wang, B., Dragosavac, M. M.,& Holdich, R. G.. (2014). Production of food-grade multiple emulsions with high encapsulation yield using oscillating membrane emulsification. in Colloids and Surfaces. A: Physicochemical and Engineering Aspects, 458, 78-84.
https://doi.org/10.1016/j.colsurfa.2014.05.011

Vladisavljević GT, Wang B, Dragosavac MM, Holdich RG. Production of food-grade multiple emulsions with high encapsulation yield using oscillating membrane emulsification. in Colloids and Surfaces. A: Physicochemical and Engineering Aspects. 2014;458:78-84.
doi:10.1016/j.colsurfa.2014.05.011 .

Vladisavljević, Goran T., Wang, Bing, Dragosavac, Marijana M., Holdich, Richard G., "Production of food-grade multiple emulsions with high encapsulation yield using oscillating membrane emulsification" in Colloids and Surfaces. A: Physicochemical and Engineering Aspects, 458 (2014):78-84,
https://doi.org/10.1016/j.colsurfa.2014.05.011 . .

TY  - CONF
AU  - Dragosavac, Marijana M.
AU  - Vladisavljević, Goran T.
AU  - Holdich, Richard G.
AU  - Stillwell, Michael T.
PY  - 2012
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/6980
AB  - A membrane emulsification method for production of monodispersed silica-based ion exchange particles through water-in-oil emulsion route is developed. A hydrophobic microsieve membrane with 15 mu m pore size and 200 pm pore spacing was used to produce droplets, with a mean size between 65 and 240 pm containing acidified sodium silicate solution (with 4 and 6 wt% SiO2) in kerosene. After drying, the final silica particles had a mean size in the range between 30 and 70 mu m. Coefficient of variation for both the droplets and particles did not exceed 35%. The most uniform particles had a mean diameter of 40 mu m and coefficient of variation of 17%. The particles were functionalised with 3-aminopropyltrimethoxysilane and used for chemisorption of Cu(II) from an aqueous solution of CuSO4 in a continuous flow stirred cell with slotted pore microfiltration membrane. Functionalised silica particles showed a higher binding affinity toward Cu(II) than nontreated silica particles.
C3  - Progress in Colloid and Polymer Science
T1  - Novel Membrane Emulsification Method of Producing Highly Uniform Silica Particles Using Inexpensive Silica Sources
VL  - 139
SP  - 7
EP  - +
DO  - 10.1007/978-3-642-28974-3_2
ER  - 

@conference{
author = "Dragosavac, Marijana M. and Vladisavljević, Goran T. and Holdich, Richard G. and Stillwell, Michael T.",
year = "2012",
abstract = "A membrane emulsification method for production of monodispersed silica-based ion exchange particles through water-in-oil emulsion route is developed. A hydrophobic microsieve membrane with 15 mu m pore size and 200 pm pore spacing was used to produce droplets, with a mean size between 65 and 240 pm containing acidified sodium silicate solution (with 4 and 6 wt% SiO2) in kerosene. After drying, the final silica particles had a mean size in the range between 30 and 70 mu m. Coefficient of variation for both the droplets and particles did not exceed 35%. The most uniform particles had a mean diameter of 40 mu m and coefficient of variation of 17%. The particles were functionalised with 3-aminopropyltrimethoxysilane and used for chemisorption of Cu(II) from an aqueous solution of CuSO4 in a continuous flow stirred cell with slotted pore microfiltration membrane. Functionalised silica particles showed a higher binding affinity toward Cu(II) than nontreated silica particles.",
journal = "Progress in Colloid and Polymer Science",
title = "Novel Membrane Emulsification Method of Producing Highly Uniform Silica Particles Using Inexpensive Silica Sources",
volume = "139",
pages = "7-+",
doi = "10.1007/978-3-642-28974-3_2"
}

Dragosavac, M. M., Vladisavljević, G. T., Holdich, R. G.,& Stillwell, M. T.. (2012). Novel Membrane Emulsification Method of Producing Highly Uniform Silica Particles Using Inexpensive Silica Sources. in Progress in Colloid and Polymer Science, 139, 7-+.
https://doi.org/10.1007/978-3-642-28974-3_2

Dragosavac MM, Vladisavljević GT, Holdich RG, Stillwell MT. Novel Membrane Emulsification Method of Producing Highly Uniform Silica Particles Using Inexpensive Silica Sources. in Progress in Colloid and Polymer Science. 2012;139:7-+.
doi:10.1007/978-3-642-28974-3_2 .

Dragosavac, Marijana M., Vladisavljević, Goran T., Holdich, Richard G., Stillwell, Michael T., "Novel Membrane Emulsification Method of Producing Highly Uniform Silica Particles Using Inexpensive Silica Sources" in Progress in Colloid and Polymer Science, 139 (2012):7-+,
https://doi.org/10.1007/978-3-642-28974-3_2 . .

TY  - JOUR
AU  - Dragosavac, Marijana M.
AU  - Holdich, Richard G.
AU  - Vladisavljević, Goran T.
AU  - Sovilj, Milan N.
PY  - 2012
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/4717
AB  - Stirred cell membrane emulsification was used to create double water-in-oil-in-water emulsions at the dispersed phase flux of up to 3200 L m(-2) h(-1). The oil phase was unrefined pumpkin seed oil or sunflower oil containing 30% by volume of internal water phase and the external water phase was 2% Tween 20 (polyoxyethylene sorbitan monolaurate) or 2% Pluronic F-68 (polyoxyethylene-polyoxypropylen copolymer). Using microengineered nickel membranes with pore sizes between 15 and 40 mu m, median drop sizes of double emulsion droplets were in the range between 100 and 430 mu m, depending mainly on the shear at the membrane surface and dispersed phase injection rate. In most cases the drops were very uniform, with span (i.e. 90% drop size minus 10% drop size divided by median size) values of around 0.5. This data is similar to what was obtained previously for simple O/W emulsions of the same materials. Hence, the internal water phase, and internal surfactant, 5% PGPR (polyglycerol polyricinoleate), did not adversely influence the emulsification process. A marker material, copper sulfate, was added to the internal water phase and the release of copper was monitored with respect to time. For both lipid systems, at the larger droplet size, there was a significant period of no copper release, followed by almost linear release with time. This initial period was absent when the drop size was close to 100 mu m. The initial entrapment efficiency of the copper, in all experiments, was higher than 94%. (C) 2011 Elsevier B. V. All rights reserved.
T2  - Journal of Membrane Science
T1  - Stirred cell membrane emulsification for multiple emulsions containing unrefined pumpkin seed oil with uniform droplet size
VL  - 392
SP  - 122
EP  - 129
DO  - 10.1016/j.memsci.2011.12.009
ER  - 

@article{
author = "Dragosavac, Marijana M. and Holdich, Richard G. and Vladisavljević, Goran T. and Sovilj, Milan N.",
year = "2012",
abstract = "Stirred cell membrane emulsification was used to create double water-in-oil-in-water emulsions at the dispersed phase flux of up to 3200 L m(-2) h(-1). The oil phase was unrefined pumpkin seed oil or sunflower oil containing 30% by volume of internal water phase and the external water phase was 2% Tween 20 (polyoxyethylene sorbitan monolaurate) or 2% Pluronic F-68 (polyoxyethylene-polyoxypropylen copolymer). Using microengineered nickel membranes with pore sizes between 15 and 40 mu m, median drop sizes of double emulsion droplets were in the range between 100 and 430 mu m, depending mainly on the shear at the membrane surface and dispersed phase injection rate. In most cases the drops were very uniform, with span (i.e. 90% drop size minus 10% drop size divided by median size) values of around 0.5. This data is similar to what was obtained previously for simple O/W emulsions of the same materials. Hence, the internal water phase, and internal surfactant, 5% PGPR (polyglycerol polyricinoleate), did not adversely influence the emulsification process. A marker material, copper sulfate, was added to the internal water phase and the release of copper was monitored with respect to time. For both lipid systems, at the larger droplet size, there was a significant period of no copper release, followed by almost linear release with time. This initial period was absent when the drop size was close to 100 mu m. The initial entrapment efficiency of the copper, in all experiments, was higher than 94%. (C) 2011 Elsevier B. V. All rights reserved.",
journal = "Journal of Membrane Science",
title = "Stirred cell membrane emulsification for multiple emulsions containing unrefined pumpkin seed oil with uniform droplet size",
volume = "392",
pages = "122-129",
doi = "10.1016/j.memsci.2011.12.009"
}

Dragosavac, M. M., Holdich, R. G., Vladisavljević, G. T.,& Sovilj, M. N.. (2012). Stirred cell membrane emulsification for multiple emulsions containing unrefined pumpkin seed oil with uniform droplet size. in Journal of Membrane Science, 392, 122-129.
https://doi.org/10.1016/j.memsci.2011.12.009

Dragosavac MM, Holdich RG, Vladisavljević GT, Sovilj MN. Stirred cell membrane emulsification for multiple emulsions containing unrefined pumpkin seed oil with uniform droplet size. in Journal of Membrane Science. 2012;392:122-129.
doi:10.1016/j.memsci.2011.12.009 .

Dragosavac, Marijana M., Holdich, Richard G., Vladisavljević, Goran T., Sovilj, Milan N., "Stirred cell membrane emulsification for multiple emulsions containing unrefined pumpkin seed oil with uniform droplet size" in Journal of Membrane Science, 392 (2012):122-129,
https://doi.org/10.1016/j.memsci.2011.12.009 . .

TY  - JOUR
AU  - Dragosavac, Marijana M.
AU  - Vladisavljević, Goran T.
AU  - Holdich, Richard G.
AU  - Stillwell, Michael T.
PY  - 2012
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/4644
AB  - A method for the production of near-monodispersed spherical silica particles with controllable porosity based on the formation of uniform emulsion droplets using membrane emulsification is described. A hydrophobic metal membrane with a 15 mu m pore size and 200 mu m pore spacing was used to produce near-monodispersed droplets, with a mean size that could be controlled between 65 and 240 mu m containing acidified sodium silicate solution (with 4 and 6 wt % SiO(2)) in kerosene. After drying and shrinking, the final silica particles had a mean size in the range between 30 and 70 mu m. The coefficient of variation for both the droplets and the particles did not exceed 35%. The most uniform particles had a mean diameter of 40 mu m and coefficient of variation of 17%. By altering the pH of the sodium silicate solution and aging the gel particles in water or acetone, the internal structure of the silica particles was successfully modified, and both micro- and mesoporous near-monodispersed spherical particles were produced with an average internal pore size between 1 and 6 nm and an average surface area between 360 and 750 m(2) g(-1). A material balance and particle size analysis provided identical values for the internal voidage of the particles, when compared to the voidage as determined by BET analysis.
T2  - Langmuir
T1  - Production of Porous Silica Microparticles by Membrane Emulsification
VL  - 28
IS  - 1
SP  - 134
EP  - 143
DO  - 10.1021/la202974b
ER  - 

@article{
author = "Dragosavac, Marijana M. and Vladisavljević, Goran T. and Holdich, Richard G. and Stillwell, Michael T.",
year = "2012",
abstract = "A method for the production of near-monodispersed spherical silica particles with controllable porosity based on the formation of uniform emulsion droplets using membrane emulsification is described. A hydrophobic metal membrane with a 15 mu m pore size and 200 mu m pore spacing was used to produce near-monodispersed droplets, with a mean size that could be controlled between 65 and 240 mu m containing acidified sodium silicate solution (with 4 and 6 wt % SiO(2)) in kerosene. After drying and shrinking, the final silica particles had a mean size in the range between 30 and 70 mu m. The coefficient of variation for both the droplets and the particles did not exceed 35%. The most uniform particles had a mean diameter of 40 mu m and coefficient of variation of 17%. By altering the pH of the sodium silicate solution and aging the gel particles in water or acetone, the internal structure of the silica particles was successfully modified, and both micro- and mesoporous near-monodispersed spherical particles were produced with an average internal pore size between 1 and 6 nm and an average surface area between 360 and 750 m(2) g(-1). A material balance and particle size analysis provided identical values for the internal voidage of the particles, when compared to the voidage as determined by BET analysis.",
journal = "Langmuir",
title = "Production of Porous Silica Microparticles by Membrane Emulsification",
volume = "28",
number = "1",
pages = "134-143",
doi = "10.1021/la202974b"
}

Dragosavac, M. M., Vladisavljević, G. T., Holdich, R. G.,& Stillwell, M. T.. (2012). Production of Porous Silica Microparticles by Membrane Emulsification. in Langmuir, 28(1), 134-143.
https://doi.org/10.1021/la202974b

Dragosavac MM, Vladisavljević GT, Holdich RG, Stillwell MT. Production of Porous Silica Microparticles by Membrane Emulsification. in Langmuir. 2012;28(1):134-143.
doi:10.1021/la202974b .

Dragosavac, Marijana M., Vladisavljević, Goran T., Holdich, Richard G., Stillwell, Michael T., "Production of Porous Silica Microparticles by Membrane Emulsification" in Langmuir, 28, no. 1 (2012):134-143,
https://doi.org/10.1021/la202974b . .

TY  - JOUR
AU  - Dragosavac, Marijana M.
AU  - Sovilj, Milan N.
AU  - Kosvintsev, Serguei R.
AU  - Holdich, Richard G.
AU  - Vladisavljević, Goran T.
PY  - 2008
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3518
AB  - Membrane emulsification of unrefined pumpkin seed oil was performed using microengineered flat disc membranes on top of which a paddle blade stirrer was operated to induce surface shear. The membranes used were fabricated by galvanic deposition of nickel onto a photolithographic template and contained hexagonal arrays of uniform cylindrical pores with a diameter of 19 or 40 mu m and a pore spacing of 140 mu m. The uniformly sized pumpkin seed oil drops with span values less than 0.4 were obtained at oil fluxes up to 640 L m(-2) h(-1) using 2 wt.% Tween 20 (polyoxyethylene sorbitan monolaurate) or 2-10 wt.% Pluronic F-68 (polyoxyethylene-polyoxypropylen copolymer) as an aqueous surfactant solution. Pumpkin seed oil is rich in surface active ingredients that can be adsorbed on the membrane surface, such as free fatty acids, phospholipids, and chlorophyll. The adsorption of these components on the membrane surface gradually led to membrane wetting by the oil phase and the formation of uniform drops was achieved only for dispersed phase contents less than 10 vol.% At high oil fluxes, Pluronic F-68 molecules present at a concentration of 2 wt.% could not adsorb fast enough, on the newly formed oil drops, to stabilise the expanding inter-face. (c) 2008 Elsevier B.V. All rights reserved.
T2  - Journal of Membrane Science
T1  - Controlled production of oil-in-water emulsions containing unrefined pumpkin seed oil using stirred cell membrane emulsification
VL  - 322
IS  - 1
SP  - 178
EP  - 188
DO  - 10.1016/j.memsci.2008.05.026
ER  - 

@article{
author = "Dragosavac, Marijana M. and Sovilj, Milan N. and Kosvintsev, Serguei R. and Holdich, Richard G. and Vladisavljević, Goran T.",
year = "2008",
abstract = "Membrane emulsification of unrefined pumpkin seed oil was performed using microengineered flat disc membranes on top of which a paddle blade stirrer was operated to induce surface shear. The membranes used were fabricated by galvanic deposition of nickel onto a photolithographic template and contained hexagonal arrays of uniform cylindrical pores with a diameter of 19 or 40 mu m and a pore spacing of 140 mu m. The uniformly sized pumpkin seed oil drops with span values less than 0.4 were obtained at oil fluxes up to 640 L m(-2) h(-1) using 2 wt.% Tween 20 (polyoxyethylene sorbitan monolaurate) or 2-10 wt.% Pluronic F-68 (polyoxyethylene-polyoxypropylen copolymer) as an aqueous surfactant solution. Pumpkin seed oil is rich in surface active ingredients that can be adsorbed on the membrane surface, such as free fatty acids, phospholipids, and chlorophyll. The adsorption of these components on the membrane surface gradually led to membrane wetting by the oil phase and the formation of uniform drops was achieved only for dispersed phase contents less than 10 vol.% At high oil fluxes, Pluronic F-68 molecules present at a concentration of 2 wt.% could not adsorb fast enough, on the newly formed oil drops, to stabilise the expanding inter-face. (c) 2008 Elsevier B.V. All rights reserved.",
journal = "Journal of Membrane Science",
title = "Controlled production of oil-in-water emulsions containing unrefined pumpkin seed oil using stirred cell membrane emulsification",
volume = "322",
number = "1",
pages = "178-188",
doi = "10.1016/j.memsci.2008.05.026"
}

Dragosavac, M. M., Sovilj, M. N., Kosvintsev, S. R., Holdich, R. G.,& Vladisavljević, G. T.. (2008). Controlled production of oil-in-water emulsions containing unrefined pumpkin seed oil using stirred cell membrane emulsification. in Journal of Membrane Science, 322(1), 178-188.
https://doi.org/10.1016/j.memsci.2008.05.026

Dragosavac MM, Sovilj MN, Kosvintsev SR, Holdich RG, Vladisavljević GT. Controlled production of oil-in-water emulsions containing unrefined pumpkin seed oil using stirred cell membrane emulsification. in Journal of Membrane Science. 2008;322(1):178-188.
doi:10.1016/j.memsci.2008.05.026 .

Dragosavac, Marijana M., Sovilj, Milan N., Kosvintsev, Serguei R., Holdich, Richard G., Vladisavljević, Goran T., "Controlled production of oil-in-water emulsions containing unrefined pumpkin seed oil using stirred cell membrane emulsification" in Journal of Membrane Science, 322, no. 1 (2008):178-188,
https://doi.org/10.1016/j.memsci.2008.05.026 . .