TY  - JOUR
AU  - Savić, Jasmina
AU  - Petrović, Sandra
AU  - Leskovac, Andreja
AU  - Lazarević-Pašti, Tamara
AU  - Nastasijević, Branislav J.
AU  - Tanović, Brankica B.
AU  - Gašić, Slavica M.
AU  - Vasić, Vesna M.
PY  - 2019
UR  - https://linkinghub.elsevier.com/retrieve/pii/S0308814618313670
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/7821
AB  - UV-C irradiation is widely used in the food industry. However, the health effects from dietary exposure to the irradiated pesticide residues retained in foodstuffs are underestimated. In this study, technical chlorpyrifos (TCPF) and its oil in water (EW) and emulsifiable concentrate (EC) formulations were irradiated by UV-C, and their photodegradation products were subjected to toxicity assessment, including determination of acetylcholinesterase (AChE) activity, genotoxicity and oxidative stress using human blood cells as a model system. Toxicity studies were performed using the chlorpyrifos concentrations in the range of those proposed as the maximum residue levels in plant commodities. TCPF, EW and EC photodegradation products induced DNA damage and oxidative stress, and their genotoxicity did not decrease as a function of irradiation time. Irradiated TCPF and EC are more potent AChE inhibitors than irradiated EW. Accordingly, the application of UV-C irradiation must be considered when processing the plants previously treated with chlorpyrifos formulations. © 2018 Elsevier Ltd
T2  - Food Chemistry
T1  - UV-C light irradiation enhances toxic effects of chlorpyrifos and its formulations
VL  - 271
SP  - 469
EP  - 478
DO  - 10.1016/j.foodchem.2018.07.207
ER  - 

@article{
author = "Savić, Jasmina and Petrović, Sandra and Leskovac, Andreja and Lazarević-Pašti, Tamara and Nastasijević, Branislav J. and Tanović, Brankica B. and Gašić, Slavica M. and Vasić, Vesna M.",
year = "2019",
abstract = "UV-C irradiation is widely used in the food industry. However, the health effects from dietary exposure to the irradiated pesticide residues retained in foodstuffs are underestimated. In this study, technical chlorpyrifos (TCPF) and its oil in water (EW) and emulsifiable concentrate (EC) formulations were irradiated by UV-C, and their photodegradation products were subjected to toxicity assessment, including determination of acetylcholinesterase (AChE) activity, genotoxicity and oxidative stress using human blood cells as a model system. Toxicity studies were performed using the chlorpyrifos concentrations in the range of those proposed as the maximum residue levels in plant commodities. TCPF, EW and EC photodegradation products induced DNA damage and oxidative stress, and their genotoxicity did not decrease as a function of irradiation time. Irradiated TCPF and EC are more potent AChE inhibitors than irradiated EW. Accordingly, the application of UV-C irradiation must be considered when processing the plants previously treated with chlorpyrifos formulations. © 2018 Elsevier Ltd",
journal = "Food Chemistry",
title = "UV-C light irradiation enhances toxic effects of chlorpyrifos and its formulations",
volume = "271",
pages = "469-478",
doi = "10.1016/j.foodchem.2018.07.207"
}

Savić, J., Petrović, S., Leskovac, A., Lazarević-Pašti, T., Nastasijević, B. J., Tanović, B. B., Gašić, S. M.,& Vasić, V. M.. (2019). UV-C light irradiation enhances toxic effects of chlorpyrifos and its formulations. in Food Chemistry, 271, 469-478.
https://doi.org/10.1016/j.foodchem.2018.07.207

Savić J, Petrović S, Leskovac A, Lazarević-Pašti T, Nastasijević BJ, Tanović BB, Gašić SM, Vasić VM. UV-C light irradiation enhances toxic effects of chlorpyrifos and its formulations. in Food Chemistry. 2019;271:469-478.
doi:10.1016/j.foodchem.2018.07.207 .

Savić, Jasmina, Petrović, Sandra, Leskovac, Andreja, Lazarević-Pašti, Tamara, Nastasijević, Branislav J., Tanović, Brankica B., Gašić, Slavica M., Vasić, Vesna M., "UV-C light irradiation enhances toxic effects of chlorpyrifos and its formulations" in Food Chemistry, 271 (2019):469-478,
https://doi.org/10.1016/j.foodchem.2018.07.207 . .

TY  - DATA
AU  - Savić, Jasmina
AU  - Petrović, Sandra
AU  - Leskovac, Andreja
AU  - Lazarević-Pašti, Tamara
AU  - Nastasijević, Branislav J.
AU  - Tanović, Brankica B.
AU  - Gašić, Slavica M.
AU  - Vasić, Vesna M.
PY  - 2019
UR  - https://linkinghub.elsevier.com/retrieve/pii/S0308814618313670
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/7831
AB  - Supplementary data 1: Table 1S. The chromatographic gradient profile; Table 2S. CPF concentration decrease (corresponding initial CPF concentration decrease was set as 0%) for all three forms of CPF depending on irradiation time; Table 3S. CPF and CPO concentrations determined chromatographically for TCPF, EW and EC formulations, as the function of irradiation time; % of CPO comparing to initial CPF concentration in all three forms of CPF; 
Supplementary data 2: Material safety data sheet according to 1907/2006/EC, Article 31/version 1; 
Supplementary data 3: Material safety data sheet according to 1907/2006/EC, Article 31/version 4
T2  - Food Chemistry
T1  - Supplementary data: UV-C light irradiation enhances toxic effects of chlorpyrifos and its formulations
VL  - 271
SP  - 469
EP  - 478
DO  - 10.1016/j.foodchem.2018.07.207
ER  - 

@misc{
author = "Savić, Jasmina and Petrović, Sandra and Leskovac, Andreja and Lazarević-Pašti, Tamara and Nastasijević, Branislav J. and Tanović, Brankica B. and Gašić, Slavica M. and Vasić, Vesna M.",
year = "2019",
abstract = "Supplementary data 1: Table 1S. The chromatographic gradient profile; Table 2S. CPF concentration decrease (corresponding initial CPF concentration decrease was set as 0%) for all three forms of CPF depending on irradiation time; Table 3S. CPF and CPO concentrations determined chromatographically for TCPF, EW and EC formulations, as the function of irradiation time; % of CPO comparing to initial CPF concentration in all three forms of CPF; 
Supplementary data 2: Material safety data sheet according to 1907/2006/EC, Article 31/version 1; 
Supplementary data 3: Material safety data sheet according to 1907/2006/EC, Article 31/version 4",
journal = "Food Chemistry",
title = "Supplementary data: UV-C light irradiation enhances toxic effects of chlorpyrifos and its formulations",
volume = "271",
pages = "469-478",
doi = "10.1016/j.foodchem.2018.07.207"
}

Savić, J., Petrović, S., Leskovac, A., Lazarević-Pašti, T., Nastasijević, B. J., Tanović, B. B., Gašić, S. M.,& Vasić, V. M.. (2019). Supplementary data: UV-C light irradiation enhances toxic effects of chlorpyrifos and its formulations. in Food Chemistry, 271, 469-478.
https://doi.org/10.1016/j.foodchem.2018.07.207

Savić J, Petrović S, Leskovac A, Lazarević-Pašti T, Nastasijević BJ, Tanović BB, Gašić SM, Vasić VM. Supplementary data: UV-C light irradiation enhances toxic effects of chlorpyrifos and its formulations. in Food Chemistry. 2019;271:469-478.
doi:10.1016/j.foodchem.2018.07.207 .

Savić, Jasmina, Petrović, Sandra, Leskovac, Andreja, Lazarević-Pašti, Tamara, Nastasijević, Branislav J., Tanović, Brankica B., Gašić, Slavica M., Vasić, Vesna M., "Supplementary data: UV-C light irradiation enhances toxic effects of chlorpyrifos and its formulations" in Food Chemistry, 271 (2019):469-478,
https://doi.org/10.1016/j.foodchem.2018.07.207 . .

TY  - CONF
AU  - Cvijović, Mirjana
AU  - Stanković, Srboljub
AU  - Tanović, Brankica
PY  - 2016
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12154
AB  - Pesticide residues include the remaining substances or mixtures, metabolites and impurities in food which are considered to be toxicological significance. The goal of this work was validation method for the determination of residue by UPLC PDA and GC MS techniques. Special scope has been chlorpyrifos from apple after oil and emulsion formulation Radar EW and Radar EC treatment. In order to fully respond to this task, it has been induced the degradation products of active component -chlorpyrifos from these formulations. The degradation products chlorpyrifosoxon, 3,5,6-trichloro-2-pyridinol (TCP) and o,o -diethyl thiophosphate (DTPA) received after gamma radiation samples in a permanent for 66 hours with 2,5 KGray from Co-60 source. Gamma radiation is the closest degradation to natural conditions, followed degradation path, based on the chemical and microbiological processes. Four different extraction procedures have been used: liquid-liquid extraction (Dutch procedure), solid phase extraction with HLB cartridge, multiwall carbon nano tubes and Quechers extraction. The recovery for these clean up methods has been in range 75-94%. The validation parameters for UPLC PDA has been: LOD 0,06 ppm, LOQ 0,18 ppm. The linearity was confirmed by correlation coefficient, R=0.998 for UPLC. The parameter for GC MS has been on ppm level also. The correlation coefficient for GC MS is 0.999. The result on apple samples showed that for pesticide residue quantifications is more adequate GC MS technique that is characterized by highest recovery, the lowest standard deviation and better LOQ.
PB  - Niš : University of Niš, Faculty of Electronic Engineering
C3  - RAD 2016 : 4th International Conference on Radiation and Applications in Various Fields of Research : Book of abstracts
T1  - Validation Method for Pesticide Residue after Gamma Irradiation
SP  - 452
EP  - 452
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12154
ER  - 

@conference{
author = "Cvijović, Mirjana and Stanković, Srboljub and Tanović, Brankica",
year = "2016",
abstract = "Pesticide residues include the remaining substances or mixtures, metabolites and impurities in food which are considered to be toxicological significance. The goal of this work was validation method for the determination of residue by UPLC PDA and GC MS techniques. Special scope has been chlorpyrifos from apple after oil and emulsion formulation Radar EW and Radar EC treatment. In order to fully respond to this task, it has been induced the degradation products of active component -chlorpyrifos from these formulations. The degradation products chlorpyrifosoxon, 3,5,6-trichloro-2-pyridinol (TCP) and o,o -diethyl thiophosphate (DTPA) received after gamma radiation samples in a permanent for 66 hours with 2,5 KGray from Co-60 source. Gamma radiation is the closest degradation to natural conditions, followed degradation path, based on the chemical and microbiological processes. Four different extraction procedures have been used: liquid-liquid extraction (Dutch procedure), solid phase extraction with HLB cartridge, multiwall carbon nano tubes and Quechers extraction. The recovery for these clean up methods has been in range 75-94%. The validation parameters for UPLC PDA has been: LOD 0,06 ppm, LOQ 0,18 ppm. The linearity was confirmed by correlation coefficient, R=0.998 for UPLC. The parameter for GC MS has been on ppm level also. The correlation coefficient for GC MS is 0.999. The result on apple samples showed that for pesticide residue quantifications is more adequate GC MS technique that is characterized by highest recovery, the lowest standard deviation and better LOQ.",
publisher = "Niš : University of Niš, Faculty of Electronic Engineering",
journal = "RAD 2016 : 4th International Conference on Radiation and Applications in Various Fields of Research : Book of abstracts",
title = "Validation Method for Pesticide Residue after Gamma Irradiation",
pages = "452-452",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12154"
}

Cvijović, M., Stanković, S.,& Tanović, B.. (2016). Validation Method for Pesticide Residue after Gamma Irradiation. in RAD 2016 : 4th International Conference on Radiation and Applications in Various Fields of Research : Book of abstracts
Niš : University of Niš, Faculty of Electronic Engineering., 452-452.
https://hdl.handle.net/21.15107/rcub_vinar_12154

Cvijović M, Stanković S, Tanović B. Validation Method for Pesticide Residue after Gamma Irradiation. in RAD 2016 : 4th International Conference on Radiation and Applications in Various Fields of Research : Book of abstracts. 2016;:452-452.
https://hdl.handle.net/21.15107/rcub_vinar_12154 .

Cvijović, Mirjana, Stanković, Srboljub, Tanović, Brankica, "Validation Method for Pesticide Residue after Gamma Irradiation" in RAD 2016 : 4th International Conference on Radiation and Applications in Various Fields of Research : Book of abstracts (2016):452-452,
https://hdl.handle.net/21.15107/rcub_vinar_12154 .