TY  - JOUR
AU  - Ponjavić, Marijana
AU  - Malagurski, Ivana
AU  - Lazić, Jelena
AU  - Jeremić, Sanja
AU  - Pavlović, Vladimir B.
AU  - Prlainović, Nevena
AU  - Maksimović, Vesna
AU  - Ćosović, Vladan
AU  - Atanase, Leonard Ionut
AU  - Freitas, Filomena
AU  - Matos, Mariana
AU  - Nikodinović-Runić, Jasmina
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10660
AB  - The quest for sustainable biomaterials with excellent biocompatibility and tailorableproperties has put polyhydroxyalkanoates (PHAs) into the research spotlight. However, high productioncosts and the lack of bioactivity limit their market penetration. To address this, poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) was combined with a bacterial pigment with stronganticancer activity, prodigiosin (PG), to obtain functionally enhanced PHBV-based biomaterials. Thesamples were produced in the form of films 115.6–118.8  m in thickness using the solvent castingmethod. The effects of PG incorporation on the physical properties (morphology, biopolymer crystallinityand thermal stability) and functionality of the obtained biomaterials were investigated. PGhas acted as a nucleating agent, in turn affecting the degree of crystallinity, thermal stability andmorphology of the films. All samples with PG had a more organized internal structure and highermelting and degradation temperatures. The calculated degree of crystallinity of the PHBV copolymerwas 53%, while the PG1, PG3 and PG3 films had values of 64.0%, 63.9% and 69.2%, respectively.Cytotoxicity studies have shown the excellent anticancer activity of films against HCT116 (coloncancer) cells, thus advancing PHBV biomedical application potential.
T2  - International Journal of Molecular Sciences
T1  - Advancing PHBV Biomedical Potential with the Incorporation of Bacterial Biopigment Prodigiosin
VL  - 24
IS  - 3
SP  - 1906
DO  - 10.3390/ijms24031906
ER  - 

@article{
author = "Ponjavić, Marijana and Malagurski, Ivana and Lazić, Jelena and Jeremić, Sanja and Pavlović, Vladimir B. and Prlainović, Nevena and Maksimović, Vesna and Ćosović, Vladan and Atanase, Leonard Ionut and Freitas, Filomena and Matos, Mariana and Nikodinović-Runić, Jasmina",
year = "2023",
abstract = "The quest for sustainable biomaterials with excellent biocompatibility and tailorableproperties has put polyhydroxyalkanoates (PHAs) into the research spotlight. However, high productioncosts and the lack of bioactivity limit their market penetration. To address this, poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) was combined with a bacterial pigment with stronganticancer activity, prodigiosin (PG), to obtain functionally enhanced PHBV-based biomaterials. Thesamples were produced in the form of films 115.6–118.8  m in thickness using the solvent castingmethod. The effects of PG incorporation on the physical properties (morphology, biopolymer crystallinityand thermal stability) and functionality of the obtained biomaterials were investigated. PGhas acted as a nucleating agent, in turn affecting the degree of crystallinity, thermal stability andmorphology of the films. All samples with PG had a more organized internal structure and highermelting and degradation temperatures. The calculated degree of crystallinity of the PHBV copolymerwas 53%, while the PG1, PG3 and PG3 films had values of 64.0%, 63.9% and 69.2%, respectively.Cytotoxicity studies have shown the excellent anticancer activity of films against HCT116 (coloncancer) cells, thus advancing PHBV biomedical application potential.",
journal = "International Journal of Molecular Sciences",
title = "Advancing PHBV Biomedical Potential with the Incorporation of Bacterial Biopigment Prodigiosin",
volume = "24",
number = "3",
pages = "1906",
doi = "10.3390/ijms24031906"
}

Ponjavić, M., Malagurski, I., Lazić, J., Jeremić, S., Pavlović, V. B., Prlainović, N., Maksimović, V., Ćosović, V., Atanase, L. I., Freitas, F., Matos, M.,& Nikodinović-Runić, J.. (2023). Advancing PHBV Biomedical Potential with the Incorporation of Bacterial Biopigment Prodigiosin. in International Journal of Molecular Sciences, 24(3), 1906.
https://doi.org/10.3390/ijms24031906

Ponjavić M, Malagurski I, Lazić J, Jeremić S, Pavlović VB, Prlainović N, Maksimović V, Ćosović V, Atanase LI, Freitas F, Matos M, Nikodinović-Runić J. Advancing PHBV Biomedical Potential with the Incorporation of Bacterial Biopigment Prodigiosin. in International Journal of Molecular Sciences. 2023;24(3):1906.
doi:10.3390/ijms24031906 .

Ponjavić, Marijana, Malagurski, Ivana, Lazić, Jelena, Jeremić, Sanja, Pavlović, Vladimir B., Prlainović, Nevena, Maksimović, Vesna, Ćosović, Vladan, Atanase, Leonard Ionut, Freitas, Filomena, Matos, Mariana, Nikodinović-Runić, Jasmina, "Advancing PHBV Biomedical Potential with the Incorporation of Bacterial Biopigment Prodigiosin" in International Journal of Molecular Sciences, 24, no. 3 (2023):1906,
https://doi.org/10.3390/ijms24031906 . .

TY  - CONF
AU  - Jovanović, Aleksandar
AU  - Knežević, Nataša
AU  - Čutović, Natalija
AU  - Đolić, Maja
AU  - Prlainović, Nevena
AU  - Veličković, Zlate
AU  - Vuksanović, Marija M.
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10673
AB  - Management of waste polymers (polyethylene - PE and polypropylene - PP) represents one of the major obstacles in the field of environmental protection, which demands a most efficient and eco-friendly technological solution. Due to the high use of various plastic materials, the amount of landfilled or dissipated plastic waste is continuously growing. Therefore, this paper examines the possibilities of recycling these polymers, alongside obtaining granules of similar or advanced physico-mechanical characteristics to the commercially available ones. The applied technology consists of several consecutive processes (collecting, grinding, washing and extruding) where the obtained materials can later be incorporated into widely applicable products, such as foils, bin liners, bags, among others. In this way, high-quality products with great market potential are obtained, which will consequently contribute to lower extraction and less depletion of natural resources. Thus major problems may be solved optimally, consolidating the efficiency of improved eco-friendly technologies which is in line with environmental protection and sustainable waste management.
PB  - University of Belgrade, Technical Faculty in Bor
C3  - EcoTER’22 : 29th International Conference Ecological Truth and Environmental Research : Proceedings
T1  - Improved technology for production of PE and PP regranulates
SP  - 186
EP  - 189
UR  - https://hdl.handle.net/21.15107/rcub_vinar_10673
ER  - 

@conference{
author = "Jovanović, Aleksandar and Knežević, Nataša and Čutović, Natalija and Đolić, Maja and Prlainović, Nevena and Veličković, Zlate and Vuksanović, Marija M.",
year = "2022",
abstract = "Management of waste polymers (polyethylene - PE and polypropylene - PP) represents one of the major obstacles in the field of environmental protection, which demands a most efficient and eco-friendly technological solution. Due to the high use of various plastic materials, the amount of landfilled or dissipated plastic waste is continuously growing. Therefore, this paper examines the possibilities of recycling these polymers, alongside obtaining granules of similar or advanced physico-mechanical characteristics to the commercially available ones. The applied technology consists of several consecutive processes (collecting, grinding, washing and extruding) where the obtained materials can later be incorporated into widely applicable products, such as foils, bin liners, bags, among others. In this way, high-quality products with great market potential are obtained, which will consequently contribute to lower extraction and less depletion of natural resources. Thus major problems may be solved optimally, consolidating the efficiency of improved eco-friendly technologies which is in line with environmental protection and sustainable waste management.",
publisher = "University of Belgrade, Technical Faculty in Bor",
journal = "EcoTER’22 : 29th International Conference Ecological Truth and Environmental Research : Proceedings",
title = "Improved technology for production of PE and PP regranulates",
pages = "186-189",
url = "https://hdl.handle.net/21.15107/rcub_vinar_10673"
}

Jovanović, A., Knežević, N., Čutović, N., Đolić, M., Prlainović, N., Veličković, Z.,& Vuksanović, M. M.. (2022). Improved technology for production of PE and PP regranulates. in EcoTER’22 : 29th International Conference Ecological Truth and Environmental Research : Proceedings
University of Belgrade, Technical Faculty in Bor., 186-189.
https://hdl.handle.net/21.15107/rcub_vinar_10673

Jovanović A, Knežević N, Čutović N, Đolić M, Prlainović N, Veličković Z, Vuksanović MM. Improved technology for production of PE and PP regranulates. in EcoTER’22 : 29th International Conference Ecological Truth and Environmental Research : Proceedings. 2022;:186-189.
https://hdl.handle.net/21.15107/rcub_vinar_10673 .

Jovanović, Aleksandar, Knežević, Nataša, Čutović, Natalija, Đolić, Maja, Prlainović, Nevena, Veličković, Zlate, Vuksanović, Marija M., "Improved technology for production of PE and PP regranulates" in EcoTER’22 : 29th International Conference Ecological Truth and Environmental Research : Proceedings (2022):186-189,
https://hdl.handle.net/21.15107/rcub_vinar_10673 .

Marinković, A., Tomić, N., Prlainović, N., Radovanović, Ž., Bošnjaković, J.,& Vuksanović, M.. (2021). Postupak proizvodnje plastifikatora iz otpadnog PET-a za poboljšanu termostabilnost ekspandirajućih protivpožarnih materijala. .
https://doi.org/10.5281/zenodo.8366862

Marinković A, Tomić N, Prlainović N, Radovanović Ž, Bošnjaković J, Vuksanović M. Postupak proizvodnje plastifikatora iz otpadnog PET-a za poboljšanu termostabilnost ekspandirajućih protivpožarnih materijala. 2021;.
doi:10.5281/zenodo.8366862 .

Marinković, Aleksandar, Tomić, Nataša, Prlainović, Nevena, Radovanović, Željko, Bošnjaković, Jovana, Vuksanović, Marija, "Postupak proizvodnje plastifikatora iz otpadnog PET-a za poboljšanu termostabilnost ekspandirajućih protivpožarnih materijala" (2021),
https://doi.org/10.5281/zenodo.8366862 . .