TY  - JOUR
AU  - Kovačova, Maria
AU  - Marković, Zoran M.
AU  - Humpoliček, Petr
AU  - Mičušik, Matej
AU  - Švajdlenkova, Helena
AU  - Kleinova, Angela
AU  - Danko, Martin
AU  - Kubat, Pavel
AU  - Vajdak, Jan
AU  - Capakova, Zdenka
AU  - Lehocky, Marian
AU  - Munster, Lukaš
AU  - Todorović-Marković, Biljana
AU  - Špitalsky, Zdenko
PY  - 2018
UR  - http://pubs.acs.org/doi/10.1021/acsbiomaterials.8b00582
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8064
AB  - Development of new types of antibacterial coatings or nanocomposites is of great importance due to widespread multidrug-resistant infections including bacterial infections. Herein, we investigated biocompatibility as well as structural, photocatalytic, and antibacterial properties of photoactive hydrophobic carbon quantum dots/polyurethane nanocomposite. The swell-encapsulation-shrink method was applied for production of these nanocomposites. Hydrophobic carbon quantum dots/polyurethane nanocomposites were found to be highly effective generator of singlet oxygen upon irradiation by low-power blue light. Analysis of conducted antibacterial tests on Staphyloccocus aureus and Escherichia coli showed 5-log bactericidal effect of these nanocomposites within 60 min of irradiation. Very powerful degradation of dye (rose bengal) was observed within 180 min of blue light irradiation of the nanocomposites. Biocompatibility studies revealed that nanocomposites were not cytotoxic against mouse embryonic fibroblast cell line, whereas they showed moderate cytotoxicity toward adenocarcinomic human epithelial cell line. Minor hemolytic effect of these nanocomposites toward red blood cells was revealed.
T2  - ACS Biomaterials Science and Engineering
T1  - Carbon Quantum Dots Modified Polyurethane Nanocomposite as Effective Photocatalytic and Antibacterial Agents
VL  - 4
IS  - 12
SP  - 3983
EP  - 3993
DO  - 10.1021/acsbiomaterials.8b00582
ER  - 

@article{
author = "Kovačova, Maria and Marković, Zoran M. and Humpoliček, Petr and Mičušik, Matej and Švajdlenkova, Helena and Kleinova, Angela and Danko, Martin and Kubat, Pavel and Vajdak, Jan and Capakova, Zdenka and Lehocky, Marian and Munster, Lukaš and Todorović-Marković, Biljana and Špitalsky, Zdenko",
year = "2018",
abstract = "Development of new types of antibacterial coatings or nanocomposites is of great importance due to widespread multidrug-resistant infections including bacterial infections. Herein, we investigated biocompatibility as well as structural, photocatalytic, and antibacterial properties of photoactive hydrophobic carbon quantum dots/polyurethane nanocomposite. The swell-encapsulation-shrink method was applied for production of these nanocomposites. Hydrophobic carbon quantum dots/polyurethane nanocomposites were found to be highly effective generator of singlet oxygen upon irradiation by low-power blue light. Analysis of conducted antibacterial tests on Staphyloccocus aureus and Escherichia coli showed 5-log bactericidal effect of these nanocomposites within 60 min of irradiation. Very powerful degradation of dye (rose bengal) was observed within 180 min of blue light irradiation of the nanocomposites. Biocompatibility studies revealed that nanocomposites were not cytotoxic against mouse embryonic fibroblast cell line, whereas they showed moderate cytotoxicity toward adenocarcinomic human epithelial cell line. Minor hemolytic effect of these nanocomposites toward red blood cells was revealed.",
journal = "ACS Biomaterials Science and Engineering",
title = "Carbon Quantum Dots Modified Polyurethane Nanocomposite as Effective Photocatalytic and Antibacterial Agents",
volume = "4",
number = "12",
pages = "3983-3993",
doi = "10.1021/acsbiomaterials.8b00582"
}

Kovačova, M., Marković, Z. M., Humpoliček, P., Mičušik, M., Švajdlenkova, H., Kleinova, A., Danko, M., Kubat, P., Vajdak, J., Capakova, Z., Lehocky, M., Munster, L., Todorović-Marković, B.,& Špitalsky, Z.. (2018). Carbon Quantum Dots Modified Polyurethane Nanocomposite as Effective Photocatalytic and Antibacterial Agents. in ACS Biomaterials Science and Engineering, 4(12), 3983-3993.
https://doi.org/10.1021/acsbiomaterials.8b00582

Kovačova M, Marković ZM, Humpoliček P, Mičušik M, Švajdlenkova H, Kleinova A, Danko M, Kubat P, Vajdak J, Capakova Z, Lehocky M, Munster L, Todorović-Marković B, Špitalsky Z. Carbon Quantum Dots Modified Polyurethane Nanocomposite as Effective Photocatalytic and Antibacterial Agents. in ACS Biomaterials Science and Engineering. 2018;4(12):3983-3993.
doi:10.1021/acsbiomaterials.8b00582 .

Kovačova, Maria, Marković, Zoran M., Humpoliček, Petr, Mičušik, Matej, Švajdlenkova, Helena, Kleinova, Angela, Danko, Martin, Kubat, Pavel, Vajdak, Jan, Capakova, Zdenka, Lehocky, Marian, Munster, Lukaš, Todorović-Marković, Biljana, Špitalsky, Zdenko, "Carbon Quantum Dots Modified Polyurethane Nanocomposite as Effective Photocatalytic and Antibacterial Agents" in ACS Biomaterials Science and Engineering, 4, no. 12 (2018):3983-3993,
https://doi.org/10.1021/acsbiomaterials.8b00582 . .