TY  - JOUR
AU  - Mirković, Ilinka
AU  - Nikolić, Marija
AU  - Ostojić, Sanja
AU  - Maletaškić, Jelena
AU  - Petrović, Zoran
AU  - Đonlagić, Jasna
PY  - 2020
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9718
AB  - Semi-interpenetrating polymer networks (SIPN) based on thermo-responsive poly(N-isopropylacrylamide) (PNIPA) and water-soluble sodium salts of linear hyaluronic acid (Na-HA) were physically cross-linked with synthetic nanoclay (laponite XLG). PNIPA hydrogels with different cross-linking densities and Na-HA concentrations were synthesized by in situ free-radical redox polymerization. The structure and heterogeneity of the semi-IPN hydrogels were examined by SEM and XRD. The content of clay incorporated in the gel was determined by TGA. DSC measurements showed that volume phase transition temperature and its enthalpy varied with the clay and hyaluronic acid content. SIPN hydrogels containing negatively charged polyelectrolyte, Na-HA, exhibited higher Q(e) and faster deswelling rates than the corresponding PNIPA NC hydrogels. The presence of the anionic Na-HA polymer reduced the storage modulus, indicating a weakening of the hydrogel network structure, especially at lower clay contents. The nanocomposite hydrogels exhibited high tan delta values, which increased with increasing Na-HA content.
T2  - Journal of the Serbian Chemical Society
T1  - Thermo-responsive hydrogels based on poly(N-isopropyl- acrylamide) and hyaluronic acid cross-linked with nanoclays
VL  - 85
IS  - 9
SP  - 1197
EP  - 1221
DO  - 10.2298/JSC200109023M
ER  - 

@article{
author = "Mirković, Ilinka and Nikolić, Marija and Ostojić, Sanja and Maletaškić, Jelena and Petrović, Zoran and Đonlagić, Jasna",
year = "2020",
abstract = "Semi-interpenetrating polymer networks (SIPN) based on thermo-responsive poly(N-isopropylacrylamide) (PNIPA) and water-soluble sodium salts of linear hyaluronic acid (Na-HA) were physically cross-linked with synthetic nanoclay (laponite XLG). PNIPA hydrogels with different cross-linking densities and Na-HA concentrations were synthesized by in situ free-radical redox polymerization. The structure and heterogeneity of the semi-IPN hydrogels were examined by SEM and XRD. The content of clay incorporated in the gel was determined by TGA. DSC measurements showed that volume phase transition temperature and its enthalpy varied with the clay and hyaluronic acid content. SIPN hydrogels containing negatively charged polyelectrolyte, Na-HA, exhibited higher Q(e) and faster deswelling rates than the corresponding PNIPA NC hydrogels. The presence of the anionic Na-HA polymer reduced the storage modulus, indicating a weakening of the hydrogel network structure, especially at lower clay contents. The nanocomposite hydrogels exhibited high tan delta values, which increased with increasing Na-HA content.",
journal = "Journal of the Serbian Chemical Society",
title = "Thermo-responsive hydrogels based on poly(N-isopropyl- acrylamide) and hyaluronic acid cross-linked with nanoclays",
volume = "85",
number = "9",
pages = "1197-1221",
doi = "10.2298/JSC200109023M"
}

Mirković, I., Nikolić, M., Ostojić, S., Maletaškić, J., Petrović, Z.,& Đonlagić, J.. (2020). Thermo-responsive hydrogels based on poly(N-isopropyl- acrylamide) and hyaluronic acid cross-linked with nanoclays. in Journal of the Serbian Chemical Society, 85(9), 1197-1221.
https://doi.org/10.2298/JSC200109023M

Mirković I, Nikolić M, Ostojić S, Maletaškić J, Petrović Z, Đonlagić J. Thermo-responsive hydrogels based on poly(N-isopropyl- acrylamide) and hyaluronic acid cross-linked with nanoclays. in Journal of the Serbian Chemical Society. 2020;85(9):1197-1221.
doi:10.2298/JSC200109023M .

Mirković, Ilinka, Nikolić, Marija, Ostojić, Sanja, Maletaškić, Jelena, Petrović, Zoran, Đonlagić, Jasna, "Thermo-responsive hydrogels based on poly(N-isopropyl- acrylamide) and hyaluronic acid cross-linked with nanoclays" in Journal of the Serbian Chemical Society, 85, no. 9 (2020):1197-1221,
https://doi.org/10.2298/JSC200109023M . .