TY  - JOUR
AU  - Burmester, Victoria
AU  - Nicholls, Dasha
AU  - Buckle, Alexis
AU  - Stanojević, Boban
AU  - Crous-Bou, Marta
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9872
AB  - Oxytocin, a nine amino acid peptide synthesised in the hypothalamus, has been widely recognised for its role in anxiolysis, bonding, sociality, and appetite. It binds to the oxytocin receptor (OXTR)—a G-protein coupled receptor—that is stimulated by the actions of oestrogen both peripherally and centrally. Studies have implicated OXTR genotypes in conferring either a risk or protective effect in autism, schizophrenia, and eating disorders (ED). There are numerous DNA variations of this receptor, with the most common DNA variation being in the form of the single nucleotide polymorphisms (SNPs). Two OXTR SNPs have been most studied in relation to ED: rs53576 and rs2254298. Each SNP has the same allelic variant that produces genotypes AA, AG, and GG. In this critical review we will evaluate the putative role of rs53576 and rs2254298 SNPs in ED. Additionally, this narrative review will consider the role of gene-environment interactions in the development of ED pathology.
T2  - Journal of Eating Disorders
T1  - Review of eating disorders and oxytocin receptor polymorphisms
VL  - 9
IS  - 1
SP  - 85
DO  - 10.1186/s40337-021-00438-0
ER  - 

@article{
author = "Burmester, Victoria and Nicholls, Dasha and Buckle, Alexis and Stanojević, Boban and Crous-Bou, Marta",
year = "2021",
abstract = "Oxytocin, a nine amino acid peptide synthesised in the hypothalamus, has been widely recognised for its role in anxiolysis, bonding, sociality, and appetite. It binds to the oxytocin receptor (OXTR)—a G-protein coupled receptor—that is stimulated by the actions of oestrogen both peripherally and centrally. Studies have implicated OXTR genotypes in conferring either a risk or protective effect in autism, schizophrenia, and eating disorders (ED). There are numerous DNA variations of this receptor, with the most common DNA variation being in the form of the single nucleotide polymorphisms (SNPs). Two OXTR SNPs have been most studied in relation to ED: rs53576 and rs2254298. Each SNP has the same allelic variant that produces genotypes AA, AG, and GG. In this critical review we will evaluate the putative role of rs53576 and rs2254298 SNPs in ED. Additionally, this narrative review will consider the role of gene-environment interactions in the development of ED pathology.",
journal = "Journal of Eating Disorders",
title = "Review of eating disorders and oxytocin receptor polymorphisms",
volume = "9",
number = "1",
pages = "85",
doi = "10.1186/s40337-021-00438-0"
}

Burmester, V., Nicholls, D., Buckle, A., Stanojević, B.,& Crous-Bou, M.. (2021). Review of eating disorders and oxytocin receptor polymorphisms. in Journal of Eating Disorders, 9(1), 85.
https://doi.org/10.1186/s40337-021-00438-0

Burmester V, Nicholls D, Buckle A, Stanojević B, Crous-Bou M. Review of eating disorders and oxytocin receptor polymorphisms. in Journal of Eating Disorders. 2021;9(1):85.
doi:10.1186/s40337-021-00438-0 .

Burmester, Victoria, Nicholls, Dasha, Buckle, Alexis, Stanojević, Boban, Crous-Bou, Marta, "Review of eating disorders and oxytocin receptor polymorphisms" in Journal of Eating Disorders, 9, no. 1 (2021):85,
https://doi.org/10.1186/s40337-021-00438-0 . .