TY  - CONF
AU  - Tomasović, Martina
AU  - Sinik, Marija
AU  - Joksimović, Bojan
AU  - Lacković, Milena
AU  - Samardžić, Vladimir
AU  - Vujović, Marina
AU  - Gluvić, Zoran
AU  - Obradović, Milan
AU  - Zafirović, Sonja
AU  - Isenović, Esma R.
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12029
AB  - Propylthiouracil (PTU) sometimes induces autoimmune syndromes, such as PTU–induced lupus or vasculitis. Here we present hands and feet vasculitis-like skin changes observed several days after PTU introduction in a patient who suffered from serious diffuse toxic goiter. Because of segmental distribution, normal liver function test, and no signs of clinical deterioration, it was decided to continue PTU management and observe the patient. Primarily maculopapular rash became vesicular shortly after and then scaly. After two weeks, skin changes were entirely restored with no scaring. Taking into account thorough epidemiological survey, clinical course, and performed diagnostics, presented skin changes were diagnosed as Hand, Foot, and Mouth disease (HFMD). Clinicians must be aware of the side effects of used drugs, especially after their introduction. Some clinical presentations could only resemble expected or well-known side-effects, intolerance, or hypersensitivity to the used drug. Every clinical presentation associated with any drug introduction must be thoroughly evaluated. The presented case revealed that skin changes of HFMD mimicked PTU-induced vasculitis.
C3  - Endocrine Abstracts
T1  - Hand and foot skin changes resembling PTU-induced vasculitis in a young male with diffuse toxic goiter- a case report
DO  - 10.1530/endoabs.81.EP1030
ER  - 

@conference{
author = "Tomasović, Martina and Sinik, Marija and Joksimović, Bojan and Lacković, Milena and Samardžić, Vladimir and Vujović, Marina and Gluvić, Zoran and Obradović, Milan and Zafirović, Sonja and Isenović, Esma R.",
year = "2022",
abstract = "Propylthiouracil (PTU) sometimes induces autoimmune syndromes, such as PTU–induced lupus or vasculitis. Here we present hands and feet vasculitis-like skin changes observed several days after PTU introduction in a patient who suffered from serious diffuse toxic goiter. Because of segmental distribution, normal liver function test, and no signs of clinical deterioration, it was decided to continue PTU management and observe the patient. Primarily maculopapular rash became vesicular shortly after and then scaly. After two weeks, skin changes were entirely restored with no scaring. Taking into account thorough epidemiological survey, clinical course, and performed diagnostics, presented skin changes were diagnosed as Hand, Foot, and Mouth disease (HFMD). Clinicians must be aware of the side effects of used drugs, especially after their introduction. Some clinical presentations could only resemble expected or well-known side-effects, intolerance, or hypersensitivity to the used drug. Every clinical presentation associated with any drug introduction must be thoroughly evaluated. The presented case revealed that skin changes of HFMD mimicked PTU-induced vasculitis.",
journal = "Endocrine Abstracts",
title = "Hand and foot skin changes resembling PTU-induced vasculitis in a young male with diffuse toxic goiter- a case report",
doi = "10.1530/endoabs.81.EP1030"
}

Tomasović, M., Sinik, M., Joksimović, B., Lacković, M., Samardžić, V., Vujović, M., Gluvić, Z., Obradović, M., Zafirović, S.,& Isenović, E. R.. (2022). Hand and foot skin changes resembling PTU-induced vasculitis in a young male with diffuse toxic goiter- a case report. in Endocrine Abstracts.
https://doi.org/10.1530/endoabs.81.EP1030

Tomasović M, Sinik M, Joksimović B, Lacković M, Samardžić V, Vujović M, Gluvić Z, Obradović M, Zafirović S, Isenović ER. Hand and foot skin changes resembling PTU-induced vasculitis in a young male with diffuse toxic goiter- a case report. in Endocrine Abstracts. 2022;.
doi:10.1530/endoabs.81.EP1030 .

Tomasović, Martina, Sinik, Marija, Joksimović, Bojan, Lacković, Milena, Samardžić, Vladimir, Vujović, Marina, Gluvić, Zoran, Obradović, Milan, Zafirović, Sonja, Isenović, Esma R., "Hand and foot skin changes resembling PTU-induced vasculitis in a young male with diffuse toxic goiter- a case report" in Endocrine Abstracts (2022),
https://doi.org/10.1530/endoabs.81.EP1030 . .