TY  - JOUR
AU  - Petrović, Borislava S.
AU  - Faj, Dario Z.
AU  - Marković, Mladen B.
AU  - Tot, Arpad A.
AU  - Marjanović, Milana S.
AU  - Kasabašić, Mladen D.
AU  - Gencel, Ivan V.
AU  - Paunović, Dragomir R.
AU  - Stanković, Jelena V.
AU  - Krestić-Vesović, Jelena
AU  - Mišković, Ivana M.
AU  - Čičarević, Koča B.
AU  - Bibić, Juraj I.
AU  - Budanec, Mirjana S.
AU  - Kralik, Ivana T.
AU  - Galić, Stipe J.
AU  - Hrepić, Darijo S.
AU  - Ibrišimović, Lejla A.
AU  - Davidović, Jasna Đ
AU  - Kolarević, Goran D.
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9948
AB  - The purpose of this work was to evaluate computed tomography simulators used in radio-therapy treatment planning in Serbia, Croatia, and Bosnia and Herzegovina. A survey of quality assurance programmes of 24 computed tomography simulators in 16 facilities was conducted. A dedicated CT-to-ED phantom was scanned at 120 kV and 140 kV, to obtain CT-to-ED conversion curves as well as CTDIvol. Thoracal phantoms were scanned in the standard and extended field of view to evaluate the dosimetric effect on treatment planning and delivery. The mean age of the measured scanners was 5.5 years. The mean water HU value was –6.5 (all scanners, all voltages) and air HU value was –997. Extended field of view computed tomography data differ from the standard field of view and differences between conversion curves have significant dosimetric impact. The CTDI data showed a large range of values between centers. Better quality assurance of computed tomography simulators in all countries is recommended. The CT-to-ED curve could be used as default at one voltage and per manufacturer. Extended field of view imaging can be used, but treatment planning should be avoided in the regions out of the standard field of view.
T2  - Nuclear Technology and Radiation Protection
T1  - Assessment of computed tomography simulators used in radiotherapy treatment planning in Serbia, Croatia, and Bosnia and Herzegovina
VL  - 36
IS  - 1
SP  - 97
EP  - 106
DO  - 10.2298/NTRP201118009P
ER  - 

@article{
author = "Petrović, Borislava S. and Faj, Dario Z. and Marković, Mladen B. and Tot, Arpad A. and Marjanović, Milana S. and Kasabašić, Mladen D. and Gencel, Ivan V. and Paunović, Dragomir R. and Stanković, Jelena V. and Krestić-Vesović, Jelena and Mišković, Ivana M. and Čičarević, Koča B. and Bibić, Juraj I. and Budanec, Mirjana S. and Kralik, Ivana T. and Galić, Stipe J. and Hrepić, Darijo S. and Ibrišimović, Lejla A. and Davidović, Jasna Đ and Kolarević, Goran D.",
year = "2021",
abstract = "The purpose of this work was to evaluate computed tomography simulators used in radio-therapy treatment planning in Serbia, Croatia, and Bosnia and Herzegovina. A survey of quality assurance programmes of 24 computed tomography simulators in 16 facilities was conducted. A dedicated CT-to-ED phantom was scanned at 120 kV and 140 kV, to obtain CT-to-ED conversion curves as well as CTDIvol. Thoracal phantoms were scanned in the standard and extended field of view to evaluate the dosimetric effect on treatment planning and delivery. The mean age of the measured scanners was 5.5 years. The mean water HU value was –6.5 (all scanners, all voltages) and air HU value was –997. Extended field of view computed tomography data differ from the standard field of view and differences between conversion curves have significant dosimetric impact. The CTDI data showed a large range of values between centers. Better quality assurance of computed tomography simulators in all countries is recommended. The CT-to-ED curve could be used as default at one voltage and per manufacturer. Extended field of view imaging can be used, but treatment planning should be avoided in the regions out of the standard field of view.",
journal = "Nuclear Technology and Radiation Protection",
title = "Assessment of computed tomography simulators used in radiotherapy treatment planning in Serbia, Croatia, and Bosnia and Herzegovina",
volume = "36",
number = "1",
pages = "97-106",
doi = "10.2298/NTRP201118009P"
}

Petrović, B. S., Faj, D. Z., Marković, M. B., Tot, A. A., Marjanović, M. S., Kasabašić, M. D., Gencel, I. V., Paunović, D. R., Stanković, J. V., Krestić-Vesović, J., Mišković, I. M., Čičarević, K. B., Bibić, J. I., Budanec, M. S., Kralik, I. T., Galić, S. J., Hrepić, D. S., Ibrišimović, L. A., Davidović, J. Đ.,& Kolarević, G. D.. (2021). Assessment of computed tomography simulators used in radiotherapy treatment planning in Serbia, Croatia, and Bosnia and Herzegovina. in Nuclear Technology and Radiation Protection, 36(1), 97-106.
https://doi.org/10.2298/NTRP201118009P

Petrović BS, Faj DZ, Marković MB, Tot AA, Marjanović MS, Kasabašić MD, Gencel IV, Paunović DR, Stanković JV, Krestić-Vesović J, Mišković IM, Čičarević KB, Bibić JI, Budanec MS, Kralik IT, Galić SJ, Hrepić DS, Ibrišimović LA, Davidović JĐ, Kolarević GD. Assessment of computed tomography simulators used in radiotherapy treatment planning in Serbia, Croatia, and Bosnia and Herzegovina. in Nuclear Technology and Radiation Protection. 2021;36(1):97-106.
doi:10.2298/NTRP201118009P .

Petrović, Borislava S., Faj, Dario Z., Marković, Mladen B., Tot, Arpad A., Marjanović, Milana S., Kasabašić, Mladen D., Gencel, Ivan V., Paunović, Dragomir R., Stanković, Jelena V., Krestić-Vesović, Jelena, Mišković, Ivana M., Čičarević, Koča B., Bibić, Juraj I., Budanec, Mirjana S., Kralik, Ivana T., Galić, Stipe J., Hrepić, Darijo S., Ibrišimović, Lejla A., Davidović, Jasna Đ, Kolarević, Goran D., "Assessment of computed tomography simulators used in radiotherapy treatment planning in Serbia, Croatia, and Bosnia and Herzegovina" in Nuclear Technology and Radiation Protection, 36, no. 1 (2021):97-106,
https://doi.org/10.2298/NTRP201118009P . .

TY  - JOUR
AU  - Petrović, Borislava
AU  - Vicko, Ferenc
AU  - Radovanović, Dragana
AU  - Samac, Jelena
AU  - Tot, Arpad
AU  - Radovanović, Zoran
AU  - Ivković- Kapicl, Tatjana
AU  - Lukić, Dejan
AU  - Marjanović, Milana
AU  - Ivanov, Olivera
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10039
AB  - IntroductionSentinel node biopsy is a procedure used for axillary nodal staging in breast cancer surgery. The process uses radioactive 99mTc isotope for mapping the sentinel node(s) and all the staff involved in the procedure is potentially exposed to ionizing radiation. The colloid for radiolabelling (antimone-sulphide) with 99mTc isotope (half-life 6 h) is injected into the patient breast. The injection has activity of 18.5 MBq. The surgeon removes the primary tumor and detects active lymph nodes with gamma detection unit. The tumor as well as the active nodal tissue is transferred to pathologist for the definitive findings. The aim of the study was to measure dose equivalents to extremities and whole body for all staff and suggest practice improvement in order to minimize exposure risk.Materials and methodsThe measurements of the following operational quantities were performed: Hp(10) personal dose equivalent to whole body and Hp(0.07) to extremities for staff as well as ambiental dose for operating theatre and during injection. Hp(0.07) were measured at surgeon’s finger by ring thermoluminescent dosimeter (TLD) type MTS-N, and reader RADOS RE2000. Surgeon and nurse were wearing TLD personal dosimeter at the chest level. Anesthesiologist and anesthetist were wearing electronic personal dosimeters, while pathologist was wearing ring TLD while manipulating tissue samples. Electronic dosimeters used were manufactured by Polimaster, type PM1610. All TLD and electronic dosimeters data were reported, including background radiation. Background radiation was also monitored separately. Personal TLDs are standard for this type of personal monitoring, provided by accredited laboratory. Measurements of ambiental dose in workplaces of other staff involved around the patient was performed before the surgery took place, by calibrated survey meters manufactured by Atomtex, type 1667. The study involved two surgeons and one pathologist, two anesthesiologists and three anesthetists during two months period.Results and discussionThe doses received by all staff are evaluated using passive and active personal dosimeters and ambiental dose monitors and practice was improved based on results collected. Average annual whole body dose for all staff involved in the procedure was less than 0.8 mSv. Extremity dose equivalents to surgeon and pathologist were far below the limits set for professionally exposed (surgeon) and for public (pathologist).ConclusionsAlthough has proven to be very safe for all staff, additional measures for radiation protection, in accordance to ALARA principle (As Low As Reasonably Achievable) should be conducted. The recommendations for practice improvement with respect to radiation protection were issued.
T2  - Physica Medica
T1  - Occupational radiation dose of personnel involved in sentinel node biopsy procedure
VL  - 91
SP  - 117
EP  - 120
DO  - 10.1016/j.ejmp.2021.10.019
ER  - 

@article{
author = "Petrović, Borislava and Vicko, Ferenc and Radovanović, Dragana and Samac, Jelena and Tot, Arpad and Radovanović, Zoran and Ivković- Kapicl, Tatjana and Lukić, Dejan and Marjanović, Milana and Ivanov, Olivera",
year = "2021",
abstract = "IntroductionSentinel node biopsy is a procedure used for axillary nodal staging in breast cancer surgery. The process uses radioactive 99mTc isotope for mapping the sentinel node(s) and all the staff involved in the procedure is potentially exposed to ionizing radiation. The colloid for radiolabelling (antimone-sulphide) with 99mTc isotope (half-life 6 h) is injected into the patient breast. The injection has activity of 18.5 MBq. The surgeon removes the primary tumor and detects active lymph nodes with gamma detection unit. The tumor as well as the active nodal tissue is transferred to pathologist for the definitive findings. The aim of the study was to measure dose equivalents to extremities and whole body for all staff and suggest practice improvement in order to minimize exposure risk.Materials and methodsThe measurements of the following operational quantities were performed: Hp(10) personal dose equivalent to whole body and Hp(0.07) to extremities for staff as well as ambiental dose for operating theatre and during injection. Hp(0.07) were measured at surgeon’s finger by ring thermoluminescent dosimeter (TLD) type MTS-N, and reader RADOS RE2000. Surgeon and nurse were wearing TLD personal dosimeter at the chest level. Anesthesiologist and anesthetist were wearing electronic personal dosimeters, while pathologist was wearing ring TLD while manipulating tissue samples. Electronic dosimeters used were manufactured by Polimaster, type PM1610. All TLD and electronic dosimeters data were reported, including background radiation. Background radiation was also monitored separately. Personal TLDs are standard for this type of personal monitoring, provided by accredited laboratory. Measurements of ambiental dose in workplaces of other staff involved around the patient was performed before the surgery took place, by calibrated survey meters manufactured by Atomtex, type 1667. The study involved two surgeons and one pathologist, two anesthesiologists and three anesthetists during two months period.Results and discussionThe doses received by all staff are evaluated using passive and active personal dosimeters and ambiental dose monitors and practice was improved based on results collected. Average annual whole body dose for all staff involved in the procedure was less than 0.8 mSv. Extremity dose equivalents to surgeon and pathologist were far below the limits set for professionally exposed (surgeon) and for public (pathologist).ConclusionsAlthough has proven to be very safe for all staff, additional measures for radiation protection, in accordance to ALARA principle (As Low As Reasonably Achievable) should be conducted. The recommendations for practice improvement with respect to radiation protection were issued.",
journal = "Physica Medica",
title = "Occupational radiation dose of personnel involved in sentinel node biopsy procedure",
volume = "91",
pages = "117-120",
doi = "10.1016/j.ejmp.2021.10.019"
}

Petrović, B., Vicko, F., Radovanović, D., Samac, J., Tot, A., Radovanović, Z., Ivković- Kapicl, T., Lukić, D., Marjanović, M.,& Ivanov, O.. (2021). Occupational radiation dose of personnel involved in sentinel node biopsy procedure. in Physica Medica, 91, 117-120.
https://doi.org/10.1016/j.ejmp.2021.10.019

Petrović B, Vicko F, Radovanović D, Samac J, Tot A, Radovanović Z, Ivković- Kapicl T, Lukić D, Marjanović M, Ivanov O. Occupational radiation dose of personnel involved in sentinel node biopsy procedure. in Physica Medica. 2021;91:117-120.
doi:10.1016/j.ejmp.2021.10.019 .

Petrović, Borislava, Vicko, Ferenc, Radovanović, Dragana, Samac, Jelena, Tot, Arpad, Radovanović, Zoran, Ivković- Kapicl, Tatjana, Lukić, Dejan, Marjanović, Milana, Ivanov, Olivera, "Occupational radiation dose of personnel involved in sentinel node biopsy procedure" in Physica Medica, 91 (2021):117-120,
https://doi.org/10.1016/j.ejmp.2021.10.019 . .

TY  - JOUR
AU  - Marjanović, Milana S.
AU  - Tóth, Árpad
AU  - Petrović, Borislava
AU  - Gencel, Ivan V.
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10218
AB  - The aim of this study was to assess volumetric imaging dose and image quality during radiotherapy in case of Hodgkin lymphoma. The absorbed doses were measured using ionization chamber in thorax phantom. For the same setup, Monte Carlo simulations were performed. The image quality was assessed using Catphan phantom. The absorbed doses ranged from 4.4–7.7 mGy (full rotation) and 1.1–3 mGy (partial rotation). Doses from simulation ranged from 6.8–15.6 mGy (full rotation) and 1.9–10.4 mGy (partial rotation). The image quality tests have shown differences between clinical protocols. The imaging doses were smaller than prescribed doses, but shouldn’t be neglected. © 2021, Publishing House of the Romanian Academy. All rights reserved.
T2  - Romanian Journal of Physics
T1  - Estimation of absorbed doses to target and healthy tissues during cone-beam ct radiotherapy imaging of the chest
VL  - 66
IS  - 9-10
UR  - https://hdl.handle.net/21.15107/rcub_vinar_10218
ER  - 

@article{
author = "Marjanović, Milana S. and Tóth, Árpad and Petrović, Borislava and Gencel, Ivan V.",
year = "2021",
abstract = "The aim of this study was to assess volumetric imaging dose and image quality during radiotherapy in case of Hodgkin lymphoma. The absorbed doses were measured using ionization chamber in thorax phantom. For the same setup, Monte Carlo simulations were performed. The image quality was assessed using Catphan phantom. The absorbed doses ranged from 4.4–7.7 mGy (full rotation) and 1.1–3 mGy (partial rotation). Doses from simulation ranged from 6.8–15.6 mGy (full rotation) and 1.9–10.4 mGy (partial rotation). The image quality tests have shown differences between clinical protocols. The imaging doses were smaller than prescribed doses, but shouldn’t be neglected. © 2021, Publishing House of the Romanian Academy. All rights reserved.",
journal = "Romanian Journal of Physics",
title = "Estimation of absorbed doses to target and healthy tissues during cone-beam ct radiotherapy imaging of the chest",
volume = "66",
number = "9-10",
url = "https://hdl.handle.net/21.15107/rcub_vinar_10218"
}

Marjanović, M. S., Tóth, Á., Petrović, B.,& Gencel, I. V.. (2021). Estimation of absorbed doses to target and healthy tissues during cone-beam ct radiotherapy imaging of the chest. in Romanian Journal of Physics, 66(9-10).
https://hdl.handle.net/21.15107/rcub_vinar_10218

Marjanović MS, Tóth Á, Petrović B, Gencel IV. Estimation of absorbed doses to target and healthy tissues during cone-beam ct radiotherapy imaging of the chest. in Romanian Journal of Physics. 2021;66(9-10).
https://hdl.handle.net/21.15107/rcub_vinar_10218 .

Marjanović, Milana S., Tóth, Árpad, Petrović, Borislava, Gencel, Ivan V., "Estimation of absorbed doses to target and healthy tissues during cone-beam ct radiotherapy imaging of the chest" in Romanian Journal of Physics, 66, no. 9-10 (2021),
https://hdl.handle.net/21.15107/rcub_vinar_10218 .

TY  - CONF
AU  - Kržanović, Nikola
AU  - Živanović, Miloš
AU  - Petrović, Borislava
AU  - Stanković, Srboljub
AU  - Ciraj-Bjelac, Olivera
AU  - Đaletić, Miloš
PY  - 2020
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/11906
AB  - Determination of dose in radiotherapy requires highly accurate dose measurements. Such measurements can only be performed by trained and competent staff, with calibrated equipment and QA/QC procedures in place. Chambers that are used for clinical measurements are usually calibrated in Secondary Standards Dosimetry laboratories in terms of dose to water. Calibrations are performed in water phantoms, usually in Co-60 beams at the depth of 5 cm. Chamber positioning is critical, because deviation from reference position of 1 mm along the beam axis introduces additional standard uncertainty of 0.5%. Deviation from reference position in other two directions is less important – standard beam size for radiotherapy calibrations is 10 cm x 10 cm, and beam non-uniformity within several millimeters of the beam center is usually insignificant. Chamber positioning can be achieved by using special chamber sleeves, made of PMMA or other water equivalent materials. This allows precise and easy positioning, but only in case that the sleeve is specifically made for the phantom type and chamber type. Other option is using screws and clamps, but human errors are more probable in this case. There is also a high risk for chamber to be tilted along one of the axes, especially for waterproof chambers with rigid plastic-coated cables, which are often curved from storage inside the boxes. A waterproof IBA CC13 chamber was calibrated in terms of dose to water in Co-60 beam. Even though appropriate chamber sleeve was available, the chamber could not fit due to thicker chamber stem. Chamber was calibrated placed directly in water, by using clamps, and this value was considered as the reference value, because it is obtained according to standard protocols. Chamber was also calibrated in two sleeves designed for larger chambers – first with air gap between chamber and sleeve wall, and second in sleeves filled with water. There was measurable difference between reference position and chamber center in the plane normal to the beam axis – 3 mm and 7 mm for two sleeves. For both sleeves, calibration coefficient increased when the sleeve was filled with water. The increase was 0.7% for larger sleeve and 0.4% for smaller. Maximum difference between reference value and calibration coefficient obtained when using sleeves was 0.5%. The differences are statistically significant when sleeves are dry, but when sleeves are filled with water, differences are smaller than statistical fluctuations. The effect of inappropriate sleeve can be taken into account by increasing the measurement uncertainty. In this case, the uncertainty was estimated at 0.5% with rectangular probability distribution and k=1.73. The combined expanded uncertainty of calibration coefficient was increased from 1.2 % to 1.3 %, which is still within the uncertainty goals. This approach can be used for other calibrations, but uncertainty should be estimated in different laboratories and for different chamber types.
PB  - Niš : Sievert Association
C3  - RAP 2020 : International conference on radiation applications; Book of abstracts
T1  - Influence of air gap and chamber positioning on radiotherapy chamber calibrations
SP  - 12
EP  - 12
UR  - https://hdl.handle.net/21.15107/rcub_vinar_11906
ER  - 

@conference{
author = "Kržanović, Nikola and Živanović, Miloš and Petrović, Borislava and Stanković, Srboljub and Ciraj-Bjelac, Olivera and Đaletić, Miloš",
year = "2020",
abstract = "Determination of dose in radiotherapy requires highly accurate dose measurements. Such measurements can only be performed by trained and competent staff, with calibrated equipment and QA/QC procedures in place. Chambers that are used for clinical measurements are usually calibrated in Secondary Standards Dosimetry laboratories in terms of dose to water. Calibrations are performed in water phantoms, usually in Co-60 beams at the depth of 5 cm. Chamber positioning is critical, because deviation from reference position of 1 mm along the beam axis introduces additional standard uncertainty of 0.5%. Deviation from reference position in other two directions is less important – standard beam size for radiotherapy calibrations is 10 cm x 10 cm, and beam non-uniformity within several millimeters of the beam center is usually insignificant. Chamber positioning can be achieved by using special chamber sleeves, made of PMMA or other water equivalent materials. This allows precise and easy positioning, but only in case that the sleeve is specifically made for the phantom type and chamber type. Other option is using screws and clamps, but human errors are more probable in this case. There is also a high risk for chamber to be tilted along one of the axes, especially for waterproof chambers with rigid plastic-coated cables, which are often curved from storage inside the boxes. A waterproof IBA CC13 chamber was calibrated in terms of dose to water in Co-60 beam. Even though appropriate chamber sleeve was available, the chamber could not fit due to thicker chamber stem. Chamber was calibrated placed directly in water, by using clamps, and this value was considered as the reference value, because it is obtained according to standard protocols. Chamber was also calibrated in two sleeves designed for larger chambers – first with air gap between chamber and sleeve wall, and second in sleeves filled with water. There was measurable difference between reference position and chamber center in the plane normal to the beam axis – 3 mm and 7 mm for two sleeves. For both sleeves, calibration coefficient increased when the sleeve was filled with water. The increase was 0.7% for larger sleeve and 0.4% for smaller. Maximum difference between reference value and calibration coefficient obtained when using sleeves was 0.5%. The differences are statistically significant when sleeves are dry, but when sleeves are filled with water, differences are smaller than statistical fluctuations. The effect of inappropriate sleeve can be taken into account by increasing the measurement uncertainty. In this case, the uncertainty was estimated at 0.5% with rectangular probability distribution and k=1.73. The combined expanded uncertainty of calibration coefficient was increased from 1.2 % to 1.3 %, which is still within the uncertainty goals. This approach can be used for other calibrations, but uncertainty should be estimated in different laboratories and for different chamber types.",
publisher = "Niš : Sievert Association",
journal = "RAP 2020 : International conference on radiation applications; Book of abstracts",
title = "Influence of air gap and chamber positioning on radiotherapy chamber calibrations",
pages = "12-12",
url = "https://hdl.handle.net/21.15107/rcub_vinar_11906"
}

Kržanović, N., Živanović, M., Petrović, B., Stanković, S., Ciraj-Bjelac, O.,& Đaletić, M.. (2020). Influence of air gap and chamber positioning on radiotherapy chamber calibrations. in RAP 2020 : International conference on radiation applications; Book of abstracts
Niš : Sievert Association., 12-12.
https://hdl.handle.net/21.15107/rcub_vinar_11906

Kržanović N, Živanović M, Petrović B, Stanković S, Ciraj-Bjelac O, Đaletić M. Influence of air gap and chamber positioning on radiotherapy chamber calibrations. in RAP 2020 : International conference on radiation applications; Book of abstracts. 2020;:12-12.
https://hdl.handle.net/21.15107/rcub_vinar_11906 .

Kržanović, Nikola, Živanović, Miloš, Petrović, Borislava, Stanković, Srboljub, Ciraj-Bjelac, Olivera, Đaletić, Miloš, "Influence of air gap and chamber positioning on radiotherapy chamber calibrations" in RAP 2020 : International conference on radiation applications; Book of abstracts (2020):12-12,
https://hdl.handle.net/21.15107/rcub_vinar_11906 .