@conference{
author = "Stanković, A. and Đurđević, V. and Kolaković, Ana and Stojković, Lj. and Živković, M.",
year = "2009",
abstract = "The effects of environmental exposures might be transmitted to cellular level through mechanisms that could vary between individuals. Gene polymorphism in GSTM1/GSTT1, both deletions in the gene, showed the significant influence in genetic association studies of air pollution. In order to analyze the association of GSTT1/GSTM1 polymorphism with respiratory and cardiovascular disease in regard to air- pollution, for the first time we detected the presence of GSTM1/GSTT1 deletion in two different environmental risk factors' populations, Belgrade and Obrenovac. The groups consisted of 71 (Belgrade)/89 (Obrenovac) participants. Genotyping was performed by multiplex PCR. The frequencies of “null” genotypes for GSTM1/GSTT1 were not significantly different between the two investigated groups (47.89%/44.94%, 15.49%/17.98%, respectively). In conclusion, the frequencies of detected “null” genotypes in investigated two population subsets of Serbian origin was similar and in range with the frequencies in other Caucasian populations.",
publisher = "NILU - Norwegian Institute for Air Research",
journal = "2nd International WeBIOPATR Workshop : "Particulate Matter-Research and Management" : Proceedings",
title = "The importance of population susceptibility to air pollution: gene candidate approach",
pages = "38-42",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12699"
}