Incerti, Sebastien

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Authority KeyName Variants
orcid::0000-0002-0619-2053
  • Incerti, Sebastien (6)
  • Incerti, S (1)

Author's Bibliography

Evaluation of early radiation DNA damage in a fractal cell nucleus model using Geant4-DNA

Sakata, Dousatsu; Lampe, Nathanael; Karamitros, Mathieu; Kyriakou, Ioanna; Belov, Oleg; Bernal, Mario A; Bolst, David; Bordage, Marie-Claude; Breton, Vincent; Brown, Jeremy M.C.; Francis, Ziad; Ivanchenko, Vladimir; Meylan, Sylvain; Murakami, Koichi; Okada, Shogo; Petrović, Ivan M.; Ristić-Fira, Aleksandra; Santin, Giovanni; Sarramia, David; Sasaki, Takashi; Shin, Wook-Geun; Tang, Nicolas; Tran, Hoang N; Villagrasa, Carmen; Emfietzoglou, Dimitris; Nieminen, Petteri; Guatelli, Susanna; Incerti, Sebastien

(2019)

TY  - JOUR
AU  - Sakata, Dousatsu
AU  - Lampe, Nathanael
AU  - Karamitros, Mathieu
AU  - Kyriakou, Ioanna
AU  - Belov, Oleg
AU  - Bernal, Mario A
AU  - Bolst, David
AU  - Bordage, Marie-Claude
AU  - Breton, Vincent
AU  - Brown, Jeremy M.C.
AU  - Francis, Ziad
AU  - Ivanchenko, Vladimir
AU  - Meylan, Sylvain
AU  - Murakami, Koichi
AU  - Okada, Shogo
AU  - Petrović, Ivan M.
AU  - Ristić-Fira, Aleksandra
AU  - Santin, Giovanni
AU  - Sarramia, David
AU  - Sasaki, Takashi
AU  - Shin, Wook-Geun
AU  - Tang, Nicolas
AU  - Tran, Hoang N
AU  - Villagrasa, Carmen
AU  - Emfietzoglou, Dimitris
AU  - Nieminen, Petteri
AU  - Guatelli, Susanna
AU  - Incerti, Sebastien
PY  - 2019
UR  - https://linkinghub.elsevier.com/retrieve/pii/S1120179719300882
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/8206
AB  - The advancement of multidisciplinary research fields dealing with ionising radiation induced biological damage – radiobiology, radiation physics, radiation protection and, in particular, medical physics – requires a clear mechanistic understanding of how cellular damage is induced by ionising radiation. Monte Carlo (MC)simulations provide a promising approach for the mechanistic simulation of radiation transport and radiation chemistry, towards the in silico simulation of early biological damage. We have recently developed a fully integrated MC simulation that calculates early single strand breaks (SSBs)and double strand breaks (DSBs)in a fractal chromatin based human cell nucleus model. The results of this simulation are almost equivalent to past MC simulations when considering direct/indirect strand break fraction, DSB yields and fragment distribution. The simulation results agree with experimental data on DSB yields within 13.6% on average and fragment distributions agree within an average of 34.8%. © 2019 Associazione Italiana di Fisica Medica
T2  - Physica Medica
T1  - Evaluation of early radiation DNA damage in a fractal cell nucleus model using Geant4-DNA
VL  - 62
SP  - 152
EP  - 157
DO  - 10.1016/j.ejmp.2019.04.010
ER  - 
@article{
author = "Sakata, Dousatsu and Lampe, Nathanael and Karamitros, Mathieu and Kyriakou, Ioanna and Belov, Oleg and Bernal, Mario A and Bolst, David and Bordage, Marie-Claude and Breton, Vincent and Brown, Jeremy M.C. and Francis, Ziad and Ivanchenko, Vladimir and Meylan, Sylvain and Murakami, Koichi and Okada, Shogo and Petrović, Ivan M. and Ristić-Fira, Aleksandra and Santin, Giovanni and Sarramia, David and Sasaki, Takashi and Shin, Wook-Geun and Tang, Nicolas and Tran, Hoang N and Villagrasa, Carmen and Emfietzoglou, Dimitris and Nieminen, Petteri and Guatelli, Susanna and Incerti, Sebastien",
year = "2019",
url = "https://linkinghub.elsevier.com/retrieve/pii/S1120179719300882, http://vinar.vin.bg.ac.rs/handle/123456789/8206",
abstract = "The advancement of multidisciplinary research fields dealing with ionising radiation induced biological damage – radiobiology, radiation physics, radiation protection and, in particular, medical physics – requires a clear mechanistic understanding of how cellular damage is induced by ionising radiation. Monte Carlo (MC)simulations provide a promising approach for the mechanistic simulation of radiation transport and radiation chemistry, towards the in silico simulation of early biological damage. We have recently developed a fully integrated MC simulation that calculates early single strand breaks (SSBs)and double strand breaks (DSBs)in a fractal chromatin based human cell nucleus model. The results of this simulation are almost equivalent to past MC simulations when considering direct/indirect strand break fraction, DSB yields and fragment distribution. The simulation results agree with experimental data on DSB yields within 13.6% on average and fragment distributions agree within an average of 34.8%. © 2019 Associazione Italiana di Fisica Medica",
journal = "Physica Medica",
title = "Evaluation of early radiation DNA damage in a fractal cell nucleus model using Geant4-DNA",
volume = "62",
pages = "152-157",
doi = "10.1016/j.ejmp.2019.04.010"
}
Sakata, D., Lampe, N., Karamitros, M., Kyriakou, I., Belov, O., Bernal, M. A., Bolst, D., Bordage, M., Breton, V., Brown, J. M.C., Francis, Z., Ivanchenko, V., Meylan, S., Murakami, K., Okada, S., Petrović, I. M., Ristić-Fira, A., Santin, G., Sarramia, D., Sasaki, T., Shin, W., Tang, N., Tran, H. N., Villagrasa, C., Emfietzoglou, D., Nieminen, P., Guatelli, S.,& Incerti, S. (2019). Evaluation of early radiation DNA damage in a fractal cell nucleus model using Geant4-DNA.
Physica Medica, 62, 152-157.
https://doi.org/10.1016/j.ejmp.2019.04.010
Sakata D, Lampe N, Karamitros M, Kyriakou I, Belov O, Bernal MA, Bolst D, Bordage M, Breton V, Brown JM, Francis Z, Ivanchenko V, Meylan S, Murakami K, Okada S, Petrović IM, Ristić-Fira A, Santin G, Sarramia D, Sasaki T, Shin W, Tang N, Tran HN, Villagrasa C, Emfietzoglou D, Nieminen P, Guatelli S, Incerti S. Evaluation of early radiation DNA damage in a fractal cell nucleus model using Geant4-DNA. Physica Medica. 2019;62:152-157
Sakata Dousatsu, Lampe Nathanael, Karamitros Mathieu, Kyriakou Ioanna, Belov Oleg, Bernal Mario A, Bolst David, Bordage Marie-Claude, Breton Vincent, Brown Jeremy M.C., Francis Ziad, Ivanchenko Vladimir, Meylan Sylvain, Murakami Koichi, Okada Shogo, Petrović Ivan M., Ristić-Fira Aleksandra, Santin Giovanni, Sarramia David, Sasaki Takashi, Shin Wook-Geun, Tang Nicolas, Tran Hoang N, Villagrasa Carmen, Emfietzoglou Dimitris, Nieminen Petteri, Guatelli Susanna, Incerti Sebastien, "Evaluation of early radiation DNA damage in a fractal cell nucleus model using Geant4-DNA" Physica Medica, 62 (2019):152-157,
https://doi.org/10.1016/j.ejmp.2019.04.010 .
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Biological outcomes of γ-radiation induced DNA damages in breast and lung cancer cells pretreated with free radical scavengers

Petković, Vladana; Keta, Otilija D.; Vidosavljević, Marija Z.; Incerti, Sebastien; Ristić-Fira, Aleksandra; Petrović, Ivan M.

(2019)

TY  - JOUR
AU  - Petković, Vladana
AU  - Keta, Otilija D.
AU  - Vidosavljević, Marija Z.
AU  - Incerti, Sebastien
AU  - Ristić-Fira, Aleksandra
AU  - Petrović, Ivan M.
PY  - 2019
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/8414
AB  - Purpose: Investigation of effects on DNA of γ-irradiated human cancer cells pretreated with free radical scavengers is aimed to create reference data which would enable assessment of the relative efficiency of high linear energy transfer (LET) radiations used in hadron therapy, i.e. protons and carbon ions. Materials and methods: MCF-7 breast and HTB177 lung cancer cells are irradiated with γ-rays. To minimize indirect effects of irradiation, dimethyl sulfoxide (DMSO) or glycerol are applied as free radical scavengers. Biological response to irradiation is evaluated through clonogenic cell survival, immunocytochemical and cell cycle analysis, as well as expression of proteins involved in DNA damage response. Results: Examined cell lines reveal similar level of radioresistance. Application of scavengers leads to the rise of cell survival and decreases the number of DNA double strand breaks in irradiated cells. Differences in cell cycle and protein expression between the two cell lines are probably caused by different DNA damage repair mechanisms that are activated. Conclusion: The obtained results show that DMSO and glycerol have good scavenging capacity, and may be used to minimize DNA damage induced by free radicals. Therefore, they will be used as the reference for comparison with high LET irradiations, as well as good experimental data suitable for validation of numerical simulations. © 2019, © 2019 Taylor & Francis Group, LLC.
T2  - International Journal of Radiation Biology
T1  - Biological outcomes of γ-radiation induced DNA damages in breast and lung cancer cells pretreated with free radical scavengers
VL  - 95
IS  - 3
SP  - 274
EP  - 285
DO  - 10.1080/09553002.2019.1549753
ER  - 
@article{
author = "Petković, Vladana and Keta, Otilija D. and Vidosavljević, Marija Z. and Incerti, Sebastien and Ristić-Fira, Aleksandra and Petrović, Ivan M.",
year = "2019",
url = "http://vinar.vin.bg.ac.rs/handle/123456789/8414",
abstract = "Purpose: Investigation of effects on DNA of γ-irradiated human cancer cells pretreated with free radical scavengers is aimed to create reference data which would enable assessment of the relative efficiency of high linear energy transfer (LET) radiations used in hadron therapy, i.e. protons and carbon ions. Materials and methods: MCF-7 breast and HTB177 lung cancer cells are irradiated with γ-rays. To minimize indirect effects of irradiation, dimethyl sulfoxide (DMSO) or glycerol are applied as free radical scavengers. Biological response to irradiation is evaluated through clonogenic cell survival, immunocytochemical and cell cycle analysis, as well as expression of proteins involved in DNA damage response. Results: Examined cell lines reveal similar level of radioresistance. Application of scavengers leads to the rise of cell survival and decreases the number of DNA double strand breaks in irradiated cells. Differences in cell cycle and protein expression between the two cell lines are probably caused by different DNA damage repair mechanisms that are activated. Conclusion: The obtained results show that DMSO and glycerol have good scavenging capacity, and may be used to minimize DNA damage induced by free radicals. Therefore, they will be used as the reference for comparison with high LET irradiations, as well as good experimental data suitable for validation of numerical simulations. © 2019, © 2019 Taylor & Francis Group, LLC.",
journal = "International Journal of Radiation Biology",
title = "Biological outcomes of γ-radiation induced DNA damages in breast and lung cancer cells pretreated with free radical scavengers",
volume = "95",
number = "3",
pages = "274-285",
doi = "10.1080/09553002.2019.1549753"
}
Petković, V., Keta, O. D., Vidosavljević, M. Z., Incerti, S., Ristić-Fira, A.,& Petrović, I. M. (2019). Biological outcomes of γ-radiation induced DNA damages in breast and lung cancer cells pretreated with free radical scavengers.
International Journal of Radiation Biology, 95(3), 274-285.
https://doi.org/10.1080/09553002.2019.1549753
Petković V, Keta OD, Vidosavljević MZ, Incerti S, Ristić-Fira A, Petrović IM. Biological outcomes of γ-radiation induced DNA damages in breast and lung cancer cells pretreated with free radical scavengers. International Journal of Radiation Biology. 2019;95(3):274-285
Petković Vladana, Keta Otilija D., Vidosavljević Marija Z., Incerti Sebastien, Ristić-Fira Aleksandra, Petrović Ivan M., "Biological outcomes of γ-radiation induced DNA damages in breast and lung cancer cells pretreated with free radical scavengers" International Journal of Radiation Biology, 95, no. 3 (2019):274-285,
https://doi.org/10.1080/09553002.2019.1549753 .
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Recent developments in Geant4

Allison, J; Amako, K; Apostolakis, J; Arce, P; Asai, M; Aso, T; Bagli, E; Bagulya, A; Banerjee, S; Barrand, G; Beck, B.R.; Bogdanov, A.G.; Brandt, D; Brown, J.M.C.; Burkhardt, H; Canal, Ph.; Cano-Ott, D; Chauvie, S; Cho, K; Cirrone, Giuseppe Antonio Pablo; Cooperman, G; Cortés-Giraldo, M.A.; Cosmo, G; Cuttone, Giacomo; Depaola, G; Desorgher, L; Dong, X; Dotti, A; Elvira, V.D.; Folger, G; Francis, Z; Galoyan, A; Garnier, L; Gayer, M; Genser, K.L.; Grichine, V.M.; Guatelli, S; Guèye, P; Gumplinger, P; Howard, A.S.; Hřivnáčová, I; Hwang, S; Incerti, S; Ivanchenko, A.; Ivanchenko, V.N.; Jones, F.W.; Jun, S.Y.; Kaitaniemi, P; Karakatsanis, N; Karamitros, M; Kelsey, M; Kimura, A; Koi, T; Kurashige, H; Lechner, A; Lee, S.B.; Longo, F; Maire, M; Mancusi, D; Mantero, A; Mendoza, E; Morgan, B; Murakami, K; Nikitina, T; Pandola, L; Paprocki, P; Perl, J; Petrović, Ivan M.; Pia, M.G.; Pokorski, W; Quesada, J.M.; Raine, M; Reis, M.A.; Ribon, A; Ristić-Fira, Aleksandra; Romano, Francesco; Russo, G; Santin, G; Sasaki, T; Sawkey, D; Shin, J.I.; Strakovsky, I.I.; Taborda, A; Tanaka, S; Tomé, B; Toshito, T; Tran, H.N.; Truscott, P.R.; Urban, L; Uzhinsky, V; Verbeke, J.M.; Verderi, M; Wendt, B.L.; Wenzel, H; Wright, D.H.; Wright, D.M.; Yamashita, T; Yarba, J; Yoshida, H

(2016)

TY  - JOUR
AU  - Allison, J
AU  - Amako, K
AU  - Apostolakis, J
AU  - Arce, P
AU  - Asai, M
AU  - Aso, T
AU  - Bagli, E
AU  - Bagulya, A
AU  - Banerjee, S
AU  - Barrand, G
AU  - Beck, B.R.
AU  - Bogdanov, A.G.
AU  - Brandt, D
AU  - Brown, J.M.C.
AU  - Burkhardt, H
AU  - Canal, Ph.
AU  - Cano-Ott, D
AU  - Chauvie, S
AU  - Cho, K
AU  - Cirrone, Giuseppe Antonio Pablo
AU  - Cooperman, G
AU  - Cortés-Giraldo, M.A.
AU  - Cosmo, G
AU  - Cuttone, Giacomo
AU  - Depaola, G
AU  - Desorgher, L
AU  - Dong, X
AU  - Dotti, A
AU  - Elvira, V.D.
AU  - Folger, G
AU  - Francis, Z
AU  - Galoyan, A
AU  - Garnier, L
AU  - Gayer, M
AU  - Genser, K.L.
AU  - Grichine, V.M.
AU  - Guatelli, S
AU  - Guèye, P
AU  - Gumplinger, P
AU  - Howard, A.S.
AU  - Hřivnáčová, I
AU  - Hwang, S
AU  - Incerti, S
AU  - Ivanchenko, A.
AU  - Ivanchenko, V.N.
AU  - Jones, F.W.
AU  - Jun, S.Y.
AU  - Kaitaniemi, P
AU  - Karakatsanis, N
AU  - Karamitros, M
AU  - Kelsey, M
AU  - Kimura, A
AU  - Koi, T
AU  - Kurashige, H
AU  - Lechner, A
AU  - Lee, S.B.
AU  - Longo, F
AU  - Maire, M
AU  - Mancusi, D
AU  - Mantero, A
AU  - Mendoza, E
AU  - Morgan, B
AU  - Murakami, K
AU  - Nikitina, T
AU  - Pandola, L
AU  - Paprocki, P
AU  - Perl, J
AU  - Petrović, Ivan M.
AU  - Pia, M.G.
AU  - Pokorski, W
AU  - Quesada, J.M.
AU  - Raine, M
AU  - Reis, M.A.
AU  - Ribon, A
AU  - Ristić-Fira, Aleksandra
AU  - Romano, Francesco
AU  - Russo, G
AU  - Santin, G
AU  - Sasaki, T
AU  - Sawkey, D
AU  - Shin, J.I.
AU  - Strakovsky, I.I.
AU  - Taborda, A
AU  - Tanaka, S
AU  - Tomé, B
AU  - Toshito, T
AU  - Tran, H.N.
AU  - Truscott, P.R.
AU  - Urban, L
AU  - Uzhinsky, V
AU  - Verbeke, J.M.
AU  - Verderi, M
AU  - Wendt, B.L.
AU  - Wenzel, H
AU  - Wright, D.H.
AU  - Wright, D.M.
AU  - Yamashita, T
AU  - Yarba, J
AU  - Yoshida, H
PY  - 2016
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/8645
AB  - Geant4 is a software toolkit for the simulation of the passage of particles through matter. It is used by a large number of experiments and projects in a variety of application domains, including high energy physics, astrophysics and space science, medical physics and radiation protection. Over the past several years, major changes have been made to the toolkit in order to accommodate the needs of these user communities, and to efficiently exploit the growth of computing power made available by advances in technology. The adaptation of Geant4 to multithreading, advances in physics, detector modeling and visualization, extensions to the toolkit, including biasing and reverse Monte Carlo, and tools for physics and release validation are discussed here.
T2  - Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
T1  - Recent developments in Geant4
VL  - 835
SP  - 186
EP  - 225
DO  - 10.1016/j.nima.2016.06.125
ER  - 
@article{
author = "Allison, J and Amako, K and Apostolakis, J and Arce, P and Asai, M and Aso, T and Bagli, E and Bagulya, A and Banerjee, S and Barrand, G and Beck, B.R. and Bogdanov, A.G. and Brandt, D and Brown, J.M.C. and Burkhardt, H and Canal, Ph. and Cano-Ott, D and Chauvie, S and Cho, K and Cirrone, Giuseppe Antonio Pablo and Cooperman, G and Cortés-Giraldo, M.A. and Cosmo, G and Cuttone, Giacomo and Depaola, G and Desorgher, L and Dong, X and Dotti, A and Elvira, V.D. and Folger, G and Francis, Z and Galoyan, A and Garnier, L and Gayer, M and Genser, K.L. and Grichine, V.M. and Guatelli, S and Guèye, P and Gumplinger, P and Howard, A.S. and Hřivnáčová, I and Hwang, S and Incerti, S and Ivanchenko, A. and Ivanchenko, V.N. and Jones, F.W. and Jun, S.Y. and Kaitaniemi, P and Karakatsanis, N and Karamitros, M and Kelsey, M and Kimura, A and Koi, T and Kurashige, H and Lechner, A and Lee, S.B. and Longo, F and Maire, M and Mancusi, D and Mantero, A and Mendoza, E and Morgan, B and Murakami, K and Nikitina, T and Pandola, L and Paprocki, P and Perl, J and Petrović, Ivan M. and Pia, M.G. and Pokorski, W and Quesada, J.M. and Raine, M and Reis, M.A. and Ribon, A and Ristić-Fira, Aleksandra and Romano, Francesco and Russo, G and Santin, G and Sasaki, T and Sawkey, D and Shin, J.I. and Strakovsky, I.I. and Taborda, A and Tanaka, S and Tomé, B and Toshito, T and Tran, H.N. and Truscott, P.R. and Urban, L and Uzhinsky, V and Verbeke, J.M. and Verderi, M and Wendt, B.L. and Wenzel, H and Wright, D.H. and Wright, D.M. and Yamashita, T and Yarba, J and Yoshida, H",
year = "2016",
url = "http://vinar.vin.bg.ac.rs/handle/123456789/8645",
abstract = "Geant4 is a software toolkit for the simulation of the passage of particles through matter. It is used by a large number of experiments and projects in a variety of application domains, including high energy physics, astrophysics and space science, medical physics and radiation protection. Over the past several years, major changes have been made to the toolkit in order to accommodate the needs of these user communities, and to efficiently exploit the growth of computing power made available by advances in technology. The adaptation of Geant4 to multithreading, advances in physics, detector modeling and visualization, extensions to the toolkit, including biasing and reverse Monte Carlo, and tools for physics and release validation are discussed here.",
journal = "Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment",
title = "Recent developments in Geant4",
volume = "835",
pages = "186-225",
doi = "10.1016/j.nima.2016.06.125"
}
Allison, J., Amako, K., Apostolakis, J., Arce, P., Asai, M., Aso, T., Bagli, E., Bagulya, A., Banerjee, S., Barrand, G., Beck, B.R., Bogdanov, A.G., Brandt, D., Brown, J.M.C., Burkhardt, H., Canal, Ph., Cano-Ott, D., Chauvie, S., Cho, K., Cirrone, G. A. P., Cooperman, G., Cortés-Giraldo, M.A., Cosmo, G., Cuttone, G., Depaola, G., Desorgher, L., Dong, X., Dotti, A., Elvira, V.D., Folger, G., Francis, Z., Galoyan, A., Garnier, L., Gayer, M., Genser, K.L., Grichine, V.M., Guatelli, S., Guèye, P., Gumplinger, P., Howard, A.S., Hřivnáčová, I., Hwang, S., Incerti, S., Ivanchenko, A., Ivanchenko, V.N., Jones, F.W., Jun, S.Y., Kaitaniemi, P., Karakatsanis, N., Karamitros, M., Kelsey, M., Kimura, A., Koi, T., Kurashige, H., Lechner, A., Lee, S.B., Longo, F., Maire, M., Mancusi, D., Mantero, A., Mendoza, E., Morgan, B., Murakami, K., Nikitina, T., Pandola, L., Paprocki, P., Perl, J., Petrović, I. M., Pia, M.G., Pokorski, W., Quesada, J.M., Raine, M., Reis, M.A., Ribon, A., Ristić-Fira, A., Romano, F., Russo, G., Santin, G., Sasaki, T., Sawkey, D., Shin, J.I., Strakovsky, I.I., Taborda, A., Tanaka, S., Tomé, B., Toshito, T., Tran, H.N., Truscott, P.R., Urban, L., Uzhinsky, V., Verbeke, J.M., Verderi, M., Wendt, B.L., Wenzel, H., Wright, D.H., Wright, D.M., Yamashita, T., Yarba, J.,& Yoshida, H. (2016). Recent developments in Geant4.
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 835, 186-225.
https://doi.org/10.1016/j.nima.2016.06.125
Allison J, Amako K, Apostolakis J, Arce P, Asai M, Aso T, Bagli E, Bagulya A, Banerjee S, Barrand G, Beck B, Bogdanov A, Brandt D, Brown J, Burkhardt H, Canal P, Cano-Ott D, Chauvie S, Cho K, Cirrone GAP, Cooperman G, Cortés-Giraldo M, Cosmo G, Cuttone G, Depaola G, Desorgher L, Dong X, Dotti A, Elvira V, Folger G, Francis Z, Galoyan A, Garnier L, Gayer M, Genser K, Grichine V, Guatelli S, Guèye P, Gumplinger P, Howard A, Hřivnáčová I, Hwang S, Incerti S, Ivanchenko A, Ivanchenko V, Jones F, Jun S, Kaitaniemi P, Karakatsanis N, Karamitros M, Kelsey M, Kimura A, Koi T, Kurashige H, Lechner A, Lee S, Longo F, Maire M, Mancusi D, Mantero A, Mendoza E, Morgan B, Murakami K, Nikitina T, Pandola L, Paprocki P, Perl J, Petrović IM, Pia M, Pokorski W, Quesada J, Raine M, Reis M, Ribon A, Ristić-Fira A, Romano F, Russo G, Santin G, Sasaki T, Sawkey D, Shin J, Strakovsky I, Taborda A, Tanaka S, Tomé B, Toshito T, Tran H, Truscott P, Urban L, Uzhinsky V, Verbeke J, Verderi M, Wendt B, Wenzel H, Wright D, Wright D, Yamashita T, Yarba J, Yoshida H. Recent developments in Geant4. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 2016;835:186-225
Allison J, Amako K, Apostolakis J, Arce P, Asai M, Aso T, Bagli E, Bagulya A, Banerjee S, Barrand G, Beck B.R., Bogdanov A.G., Brandt D, Brown J.M.C., Burkhardt H, Canal Ph., Cano-Ott D, Chauvie S, Cho K, Cirrone Giuseppe Antonio Pablo, Cooperman G, Cortés-Giraldo M.A., Cosmo G, Cuttone Giacomo, Depaola G, Desorgher L, Dong X, Dotti A, Elvira V.D., Folger G, Francis Z, Galoyan A, Garnier L, Gayer M, Genser K.L., Grichine V.M., Guatelli S, Guèye P, Gumplinger P, Howard A.S., Hřivnáčová I, Hwang S, Incerti S, Ivanchenko A., Ivanchenko V.N., Jones F.W., Jun S.Y., Kaitaniemi P, Karakatsanis N, Karamitros M, Kelsey M, Kimura A, Koi T, Kurashige H, Lechner A, Lee S.B., Longo F, Maire M, Mancusi D, Mantero A, Mendoza E, Morgan B, Murakami K, Nikitina T, Pandola L, Paprocki P, Perl J, Petrović Ivan M., Pia M.G., Pokorski W, Quesada J.M., Raine M, Reis M.A., Ribon A, Ristić-Fira Aleksandra, Romano Francesco, Russo G, Santin G, Sasaki T, Sawkey D, Shin J.I., Strakovsky I.I., Taborda A, Tanaka S, Tomé B, Toshito T, Tran H.N., Truscott P.R., Urban L, Uzhinsky V, Verbeke J.M., Verderi M, Wendt B.L., Wenzel H, Wright D.H., Wright D.M., Yamashita T, Yarba J, Yoshida H, "Recent developments in Geant4" Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 835 (2016):186-225,
https://doi.org/10.1016/j.nima.2016.06.125 .
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The impact of autophagy on cell death modalities in CRL-5876 lung adenocarcinoma cells after their exposure to gamma-rays and/or erlotinib

Keta, Otilija D.; Bulat, Tanja M.; Golic, Igor; Incerti, Sebastien; Korac, Aleksandra; Petrović, Ivan M.; Ristić-Fira, Aleksandra

(2016)

TY  - JOUR
AU  - Keta, Otilija D.
AU  - Bulat, Tanja M.
AU  - Golic, Igor
AU  - Incerti, Sebastien
AU  - Korac, Aleksandra
AU  - Petrović, Ivan M.
AU  - Ristić-Fira, Aleksandra
PY  - 2016
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/1044
AB  - In most patients with lung cancer radiation treatment is used either as single agent or in combination with radiosensitizing drugs. However, the mechanisms underlying combined therapy and its impact on different modes of cell death have not yet been fully elucidated. We aimed to examine effects of single and combined treatments with gamma-rays and erlotinib on radioresistant CRL-5876 human lung adenocarcinoma cells with particular emphasis on cell death. CRL-5876 cells were treated with gamma-rays and/or erlotinib and changes in cell cycle, DNA repair dynamics, ultrastructure, nuclear morphology and protein expression were monitored at different time points. To reveal the relationship between types of cell death that arise after these treatments, autophagy was blocked with chloroquine. We found that higher dose of gamma-rays causes G2/M arrest while adding of erlotinib to this treatment decreases the number of cells in S phase. Impact of erlotinib on kinetics of disappearance of irradiation-induced DNA double strand breaks is reflected in the increase of residual gamma-H2AX foci after 24 h. gamma-rays provoke cytoprotective autophagy which precedes development of senescence. Erlotinib predominantly induces apoptosis and enlarges the number of apoptotic cells in the irradiated CRL-5876 cells. Chloroquine improved cytotoxicity induced by radiation and erlotinib, increased apoptosis and decreased senescence in the CRL-5876 cells. The results obtained on CRL-5876 cells indicate significant radiosensitizing effect of erlotinib and suggest that chloroquine in the combination with the above treatments may have an additional antitumor effect in lung adenocarcinoma.
T2  - Cell Biology and Toxicology
T1  - The impact of autophagy on cell death modalities in CRL-5876 lung adenocarcinoma cells after their exposure to gamma-rays and/or erlotinib
VL  - 32
IS  - 2
SP  - 83
EP  - 101
DO  - 10.1007/s10565-016-9319-z
ER  - 
@article{
author = "Keta, Otilija D. and Bulat, Tanja M. and Golic, Igor and Incerti, Sebastien and Korac, Aleksandra and Petrović, Ivan M. and Ristić-Fira, Aleksandra",
year = "2016",
url = "http://vinar.vin.bg.ac.rs/handle/123456789/1044",
abstract = "In most patients with lung cancer radiation treatment is used either as single agent or in combination with radiosensitizing drugs. However, the mechanisms underlying combined therapy and its impact on different modes of cell death have not yet been fully elucidated. We aimed to examine effects of single and combined treatments with gamma-rays and erlotinib on radioresistant CRL-5876 human lung adenocarcinoma cells with particular emphasis on cell death. CRL-5876 cells were treated with gamma-rays and/or erlotinib and changes in cell cycle, DNA repair dynamics, ultrastructure, nuclear morphology and protein expression were monitored at different time points. To reveal the relationship between types of cell death that arise after these treatments, autophagy was blocked with chloroquine. We found that higher dose of gamma-rays causes G2/M arrest while adding of erlotinib to this treatment decreases the number of cells in S phase. Impact of erlotinib on kinetics of disappearance of irradiation-induced DNA double strand breaks is reflected in the increase of residual gamma-H2AX foci after 24 h. gamma-rays provoke cytoprotective autophagy which precedes development of senescence. Erlotinib predominantly induces apoptosis and enlarges the number of apoptotic cells in the irradiated CRL-5876 cells. Chloroquine improved cytotoxicity induced by radiation and erlotinib, increased apoptosis and decreased senescence in the CRL-5876 cells. The results obtained on CRL-5876 cells indicate significant radiosensitizing effect of erlotinib and suggest that chloroquine in the combination with the above treatments may have an additional antitumor effect in lung adenocarcinoma.",
journal = "Cell Biology and Toxicology",
title = "The impact of autophagy on cell death modalities in CRL-5876 lung adenocarcinoma cells after their exposure to gamma-rays and/or erlotinib",
volume = "32",
number = "2",
pages = "83-101",
doi = "10.1007/s10565-016-9319-z"
}
Keta, O. D., Bulat, T. M., Golic, I., Incerti, S., Korac, A., Petrović, I. M.,& Ristić-Fira, A. (2016). The impact of autophagy on cell death modalities in CRL-5876 lung adenocarcinoma cells after their exposure to gamma-rays and/or erlotinib.
Cell Biology and Toxicology, 32(2), 83-101.
https://doi.org/10.1007/s10565-016-9319-z
Keta OD, Bulat TM, Golic I, Incerti S, Korac A, Petrović IM, Ristić-Fira A. The impact of autophagy on cell death modalities in CRL-5876 lung adenocarcinoma cells after their exposure to gamma-rays and/or erlotinib. Cell Biology and Toxicology. 2016;32(2):83-101
Keta Otilija D., Bulat Tanja M., Golic Igor, Incerti Sebastien, Korac Aleksandra, Petrović Ivan M., Ristić-Fira Aleksandra, "The impact of autophagy on cell death modalities in CRL-5876 lung adenocarcinoma cells after their exposure to gamma-rays and/or erlotinib" Cell Biology and Toxicology, 32, no. 2 (2016):83-101,
https://doi.org/10.1007/s10565-016-9319-z .
1
16
14
17

Track structure modeling in liquid water: A review of the Geant4-DNA very low energy extension of the Geant4 Monte Carlo simulation toolkit

Bernal, M. A.; Bordage, M. C.; Brown, J. M. C.; Davidkova, M.; Delage, E.; El Bitar, Z.; Enger, S. A.; Francis, Z.; Guatelli, S.; Ivanchenko, V. N.; Karamitros, M.; Kyriakou, I.; Maigne, L.; Meylan, S.; Murakami, K.; Okada, S.; Payno, H.; Perrot, Y.; Petrović, Ivan M.; Pham, Q. T.; Ristić-Fira, Aleksandra; Sasaki, T.; Stepan, V.; Tran, H. N.; Villagrasa, C.; Incerti, Sebastien

(2015)

TY  - JOUR
AU  - Bernal, M. A.
AU  - Bordage, M. C.
AU  - Brown, J. M. C.
AU  - Davidkova, M.
AU  - Delage, E.
AU  - El Bitar, Z.
AU  - Enger, S. A.
AU  - Francis, Z.
AU  - Guatelli, S.
AU  - Ivanchenko, V. N.
AU  - Karamitros, M.
AU  - Kyriakou, I.
AU  - Maigne, L.
AU  - Meylan, S.
AU  - Murakami, K.
AU  - Okada, S.
AU  - Payno, H.
AU  - Perrot, Y.
AU  - Petrović, Ivan M.
AU  - Pham, Q. T.
AU  - Ristić-Fira, Aleksandra
AU  - Sasaki, T.
AU  - Stepan, V.
AU  - Tran, H. N.
AU  - Villagrasa, C.
AU  - Incerti, Sebastien
PY  - 2015
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/859
AB  - Understanding the fundamental mechanisms involved in the induction of biological damage by ionizing radiation remains a major challenge of todays radiobiology research. The Monte Carlo simulation of physical, physicochemical and chemical processes involved may provide a powerful tool for the simulation of early damage induction. The Geant4-DNA extension of the general purpose Monte Carlo Geant4 simulation toolkit aims to provide the scientific community with an open source access platform for the mechanistic simulation of such early damage. This paper presents the most recent review of the Geant4-DNA extension, as available to Geant4 users since June 2015 (release 10.2 Beta). In particular, the review includes the description of new physical models for the description of electron elastic and inelastic interactions in liquid water, as well as new examples dedicated to the simulation of physicochemical and chemical stages of water radiolysis. Several implementations of geometrical models of biological targets are presented as well, and the list of Geant4-DNA examples is described. (C) 2015 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.
T2  - Physica Medica -European Journal of Medical Physics
T1  - Track structure modeling in liquid water: A review of the Geant4-DNA very low energy extension of the Geant4 Monte Carlo simulation toolkit
VL  - 31
IS  - 8
SP  - 861
EP  - 874
DO  - 10.1016/j.ejmp.2015.10.087
ER  - 
@article{
author = "Bernal, M. A. and Bordage, M. C. and Brown, J. M. C. and Davidkova, M. and Delage, E. and El Bitar, Z. and Enger, S. A. and Francis, Z. and Guatelli, S. and Ivanchenko, V. N. and Karamitros, M. and Kyriakou, I. and Maigne, L. and Meylan, S. and Murakami, K. and Okada, S. and Payno, H. and Perrot, Y. and Petrović, Ivan M. and Pham, Q. T. and Ristić-Fira, Aleksandra and Sasaki, T. and Stepan, V. and Tran, H. N. and Villagrasa, C. and Incerti, Sebastien",
year = "2015",
url = "http://vinar.vin.bg.ac.rs/handle/123456789/859",
abstract = "Understanding the fundamental mechanisms involved in the induction of biological damage by ionizing radiation remains a major challenge of todays radiobiology research. The Monte Carlo simulation of physical, physicochemical and chemical processes involved may provide a powerful tool for the simulation of early damage induction. The Geant4-DNA extension of the general purpose Monte Carlo Geant4 simulation toolkit aims to provide the scientific community with an open source access platform for the mechanistic simulation of such early damage. This paper presents the most recent review of the Geant4-DNA extension, as available to Geant4 users since June 2015 (release 10.2 Beta). In particular, the review includes the description of new physical models for the description of electron elastic and inelastic interactions in liquid water, as well as new examples dedicated to the simulation of physicochemical and chemical stages of water radiolysis. Several implementations of geometrical models of biological targets are presented as well, and the list of Geant4-DNA examples is described. (C) 2015 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.",
journal = "Physica Medica -European Journal of Medical Physics",
title = "Track structure modeling in liquid water: A review of the Geant4-DNA very low energy extension of the Geant4 Monte Carlo simulation toolkit",
volume = "31",
number = "8",
pages = "861-874",
doi = "10.1016/j.ejmp.2015.10.087"
}
Bernal, M. A., Bordage, M. C., Brown, J. M. C., Davidkova, M., Delage, E., El Bitar, Z., Enger, S. A., Francis, Z., Guatelli, S., Ivanchenko, V. N., Karamitros, M., Kyriakou, I., Maigne, L., Meylan, S., Murakami, K., Okada, S., Payno, H., Perrot, Y., Petrović, I. M., Pham, Q. T., Ristić-Fira, A., Sasaki, T., Stepan, V., Tran, H. N., Villagrasa, C.,& Incerti, S. (2015). Track structure modeling in liquid water: A review of the Geant4-DNA very low energy extension of the Geant4 Monte Carlo simulation toolkit.
Physica Medica -European Journal of Medical Physics, 31(8), 861-874.
https://doi.org/10.1016/j.ejmp.2015.10.087
Bernal MA, Bordage MC, Brown JMC, Davidkova M, Delage E, El Bitar Z, Enger SA, Francis Z, Guatelli S, Ivanchenko VN, Karamitros M, Kyriakou I, Maigne L, Meylan S, Murakami K, Okada S, Payno H, Perrot Y, Petrović IM, Pham QT, Ristić-Fira A, Sasaki T, Stepan V, Tran HN, Villagrasa C, Incerti S. Track structure modeling in liquid water: A review of the Geant4-DNA very low energy extension of the Geant4 Monte Carlo simulation toolkit. Physica Medica -European Journal of Medical Physics. 2015;31(8):861-874
Bernal M. A., Bordage M. C., Brown J. M. C., Davidkova M., Delage E., El Bitar Z., Enger S. A., Francis Z., Guatelli S., Ivanchenko V. N., Karamitros M., Kyriakou I., Maigne L., Meylan S., Murakami K., Okada S., Payno H., Perrot Y., Petrović Ivan M., Pham Q. T., Ristić-Fira Aleksandra, Sasaki T., Stepan V., Tran H. N., Villagrasa C., Incerti Sebastien, "Track structure modeling in liquid water: A review of the Geant4-DNA very low energy extension of the Geant4 Monte Carlo simulation toolkit" Physica Medica -European Journal of Medical Physics, 31, no. 8 (2015):861-874,
https://doi.org/10.1016/j.ejmp.2015.10.087 .
1
235
202
218

Simulating radial dose of ion tracks in liquid water simulated with Geant4-DNA: A comparative study

Incerti, Sebastien; Psaltaki, M.; Gillet, P.; Barberet, Ph.; Bardies, M.; Bernal, M. A.; Bordage, M. -C.; Breton, V.; Davidkova, M.; Delage, E.; El Bitar, Z.; Francis, Z.; Guatelli, S.; Ivanchenko, A.; Ivanchenko, V.; Karamitros, M.; Lee, S. B.; Maigne, L.; Meylan, S.; Murakami, K.; Nieminen, P.; Payno, H.; Perrot, Y.; Petrović, Ivan M.; Pham, Q. T.; Ristić-Fira, Aleksandra; Santin, G.; Sasaki, T.; Seznec, H.; Shin, J. I.; Stepan, V.; Tran, H. N.; Villagrasa, C.; Geant4-DNA Collaboration

(2014)

TY  - JOUR
AU  - Incerti, Sebastien
AU  - Psaltaki, M.
AU  - Gillet, P.
AU  - Barberet, Ph.
AU  - Bardies, M.
AU  - Bernal, M. A.
AU  - Bordage, M. -C.
AU  - Breton, V.
AU  - Davidkova, M.
AU  - Delage, E.
AU  - El Bitar, Z.
AU  - Francis, Z.
AU  - Guatelli, S.
AU  - Ivanchenko, A.
AU  - Ivanchenko, V.
AU  - Karamitros, M.
AU  - Lee, S. B.
AU  - Maigne, L.
AU  - Meylan, S.
AU  - Murakami, K.
AU  - Nieminen, P.
AU  - Payno, H.
AU  - Perrot, Y.
AU  - Petrović, Ivan M.
AU  - Pham, Q. T.
AU  - Ristić-Fira, Aleksandra
AU  - Santin, G.
AU  - Sasaki, T.
AU  - Seznec, H.
AU  - Shin, J. I.
AU  - Stepan, V.
AU  - Tran, H. N.
AU  - Villagrasa, C.
AU  - Geant4-DNA Collaboration
PY  - 2014
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/6073
AB  - An accurate modeling of radial energy deposition around ion tracks is a key requirement of radiation transport software used for simulations in radiobiology at the sub-cellular scale. The work presented in this paper is part of the on-going benchmarking of the Geant4-DNA physics processes and models, which are available in the Geant4 Monte Carlo simulation toolkit for the low energy transport of particles in liquid water. We present for the first time radial dose distributions of incident ion tracks simulated with Geant4-DNA. Simulation results are compared to other results available in the literature, obtained from analytical calculations, step-by-step Monte Carlo simulations and measurements. They show a reasonable agreement with reference data. (C) 2014 Elsevier B.V. All rights reserved.
T2  - Nuclear Instruments and Methods in Physics Research. Section B: Beam Interactions with Materials and Atoms
T1  - Simulating radial dose of ion tracks in liquid water simulated with Geant4-DNA: A comparative study
VL  - 333
SP  - 92
EP  - 98
DO  - 10.1016/j.nimb.2014.04.025
ER  - 
@article{
author = "Incerti, Sebastien and Psaltaki, M. and Gillet, P. and Barberet, Ph. and Bardies, M. and Bernal, M. A. and Bordage, M. -C. and Breton, V. and Davidkova, M. and Delage, E. and El Bitar, Z. and Francis, Z. and Guatelli, S. and Ivanchenko, A. and Ivanchenko, V. and Karamitros, M. and Lee, S. B. and Maigne, L. and Meylan, S. and Murakami, K. and Nieminen, P. and Payno, H. and Perrot, Y. and Petrović, Ivan M. and Pham, Q. T. and Ristić-Fira, Aleksandra and Santin, G. and Sasaki, T. and Seznec, H. and Shin, J. I. and Stepan, V. and Tran, H. N. and Villagrasa, C. and Geant4-DNA Collaboration",
year = "2014",
url = "http://vinar.vin.bg.ac.rs/handle/123456789/6073",
abstract = "An accurate modeling of radial energy deposition around ion tracks is a key requirement of radiation transport software used for simulations in radiobiology at the sub-cellular scale. The work presented in this paper is part of the on-going benchmarking of the Geant4-DNA physics processes and models, which are available in the Geant4 Monte Carlo simulation toolkit for the low energy transport of particles in liquid water. We present for the first time radial dose distributions of incident ion tracks simulated with Geant4-DNA. Simulation results are compared to other results available in the literature, obtained from analytical calculations, step-by-step Monte Carlo simulations and measurements. They show a reasonable agreement with reference data. (C) 2014 Elsevier B.V. All rights reserved.",
journal = "Nuclear Instruments and Methods in Physics Research. Section B: Beam Interactions with Materials and Atoms",
title = "Simulating radial dose of ion tracks in liquid water simulated with Geant4-DNA: A comparative study",
volume = "333",
pages = "92-98",
doi = "10.1016/j.nimb.2014.04.025"
}
Incerti, S., Psaltaki, M., Gillet, P., Barberet, Ph., Bardies, M., Bernal, M. A., Bordage, M. -C., Breton, V., Davidkova, M., Delage, E., El Bitar, Z., Francis, Z., Guatelli, S., Ivanchenko, A., Ivanchenko, V., Karamitros, M., Lee, S. B., Maigne, L., Meylan, S., Murakami, K., Nieminen, P., Payno, H., Perrot, Y., Petrović, I. M., Pham, Q. T., Ristić-Fira, A., Santin, G., Sasaki, T., Seznec, H., Shin, J. I., Stepan, V., Tran, H. N., Villagrasa, C.,& Geant4-DNA Collaboration (2014). Simulating radial dose of ion tracks in liquid water simulated with Geant4-DNA: A comparative study.
Nuclear Instruments and Methods in Physics Research. Section B: Beam Interactions with Materials and Atoms, 333, 92-98.
https://doi.org/10.1016/j.nimb.2014.04.025
Incerti S, Psaltaki M, Gillet P, Barberet P, Bardies M, Bernal MA, Bordage M-, Breton V, Davidkova M, Delage E, El Bitar Z, Francis Z, Guatelli S, Ivanchenko A, Ivanchenko V, Karamitros M, Lee SB, Maigne L, Meylan S, Murakami K, Nieminen P, Payno H, Perrot Y, Petrović IM, Pham QT, Ristić-Fira A, Santin G, Sasaki T, Seznec H, Shin JI, Stepan V, Tran HN, Villagrasa C, Geant4-DNA Collaboration. Simulating radial dose of ion tracks in liquid water simulated with Geant4-DNA: A comparative study. Nuclear Instruments and Methods in Physics Research. Section B: Beam Interactions with Materials and Atoms. 2014;333:92-98
Incerti Sebastien, Psaltaki M., Gillet P., Barberet Ph., Bardies M., Bernal M. A., Bordage M. -C., Breton V., Davidkova M., Delage E., El Bitar Z., Francis Z., Guatelli S., Ivanchenko A., Ivanchenko V., Karamitros M., Lee S. B., Maigne L., Meylan S., Murakami K., Nieminen P., Payno H., Perrot Y., Petrović Ivan M., Pham Q. T., Ristić-Fira Aleksandra, Santin G., Sasaki T., Seznec H., Shin J. I., Stepan V., Tran H. N., Villagrasa C., Geant4-DNA Collaboration, "Simulating radial dose of ion tracks in liquid water simulated with Geant4-DNA: A comparative study" Nuclear Instruments and Methods in Physics Research. Section B: Beam Interactions with Materials and Atoms, 333 (2014):92-98,
https://doi.org/10.1016/j.nimb.2014.04.025 .
27
27
28

Recent Improvements in Geant4 Electromagnetic Physics Models and Interfaces

Ivanchenko, Vladimir; Apostolakis, John; Bagulya, Alexander; Abdelouahed, Haifa Ben; Black, Rachel; Bogdanov, Alexey; Burkhard, Helmut; Chauvie, Stéphane; Cirrone, Giuseppe Antonio Pablo; Cuttone, Giacomo; Depaola, Gerardo; Di Rosa, Francesco; Elles, Sabine; Francis, Ziad; Grichine, Vladimir; Gumplinger, Peter; Gueye, Paul; Incerti, Sebastien; Ivanchenko, Anton; Jacquemier, Jean; Lechner, Anton; Longo, Francesco; Kadri, Omrane; Karakatsanis, Nicolas; Karamitros, Mathieu; Kokoulin, Rostislav; Kurashige, Hisaya; Maire, Michel; Mantero, Alfonso; Mascialino, Barbara; Moscicki, Jakub; Pandola, Luciano; Perl, Joseph; Petrović, Ivan M.; Ristić-Fira, Aleksandra; Romano, Francesco; Russo, Giorgio; Santin, Giovanni; Schaelicke, Andreas; Toshito, Toshiyuki; Tran, Hoang; Urban, Laszlo; Yamashita, Tomohiro; Zacharatou, Christina

(2011)

TY  - JOUR
AU  - Ivanchenko, Vladimir
AU  - Apostolakis, John
AU  - Bagulya, Alexander
AU  - Abdelouahed, Haifa Ben
AU  - Black, Rachel
AU  - Bogdanov, Alexey
AU  - Burkhard, Helmut
AU  - Chauvie, Stéphane
AU  - Cirrone, Giuseppe Antonio Pablo
AU  - Cuttone, Giacomo
AU  - Depaola, Gerardo
AU  - Di Rosa, Francesco
AU  - Elles, Sabine
AU  - Francis, Ziad
AU  - Grichine, Vladimir
AU  - Gumplinger, Peter
AU  - Gueye, Paul
AU  - Incerti, Sebastien
AU  - Ivanchenko, Anton
AU  - Jacquemier, Jean
AU  - Lechner, Anton
AU  - Longo, Francesco
AU  - Kadri, Omrane
AU  - Karakatsanis, Nicolas
AU  - Karamitros, Mathieu
AU  - Kokoulin, Rostislav
AU  - Kurashige, Hisaya
AU  - Maire, Michel
AU  - Mantero, Alfonso
AU  - Mascialino, Barbara
AU  - Moscicki, Jakub
AU  - Pandola, Luciano
AU  - Perl, Joseph
AU  - Petrović, Ivan M.
AU  - Ristić-Fira, Aleksandra
AU  - Romano, Francesco
AU  - Russo, Giorgio
AU  - Santin, Giovanni
AU  - Schaelicke, Andreas
AU  - Toshito, Toshiyuki
AU  - Tran, Hoang
AU  - Urban, Laszlo
AU  - Yamashita, Tomohiro
AU  - Zacharatou, Christina
PY  - 2011
UR  - http://inis.iaea.org/search/search.aspx?orig_q=RN:49057834
UR  - http://www.aesj.or.jp/publication/pnst002/data/898-903.pdf
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/8641
AB  - An overview of the electromagnetic (EM) physics of the Geant4 toolkit is presented Two sets of EM models are available: the 'Standard' initially focused on high energy physics (HEP) while the 'Low-energy' was developed for medical, space and other applications The 'Standard' models provide a faster computation but are less accurate for keV energies, the 'Low-energy' models are more CPU time consuming A common interface to EM physics models has been developed allowing a natural combination of ultra-relativistic, relativistic and low-energy models for the same run providing both precision and CPU performance Due to this migration additional capabilities become available The new developments include relativistic models for bremsstrahlung and e+e- pair production, models of multiple and single scattering, hadron/ion ionization, microdosimetry for very low energies and also improvements in existing Geant4 models In parallel, validation suites and benchmarks have been intensively developed (author)
T2  - Progress in Nuclear Science and Technology
T1  - Recent Improvements in Geant4 Electromagnetic Physics Models and Interfaces
VL  - 2
SP  - 898
EP  - 903
DO  - 10.15669/pnst.2.898
ER  - 
@article{
author = "Ivanchenko, Vladimir and Apostolakis, John and Bagulya, Alexander and Abdelouahed, Haifa Ben and Black, Rachel and Bogdanov, Alexey and Burkhard, Helmut and Chauvie, Stéphane and Cirrone, Giuseppe Antonio Pablo and Cuttone, Giacomo and Depaola, Gerardo and Di Rosa, Francesco and Elles, Sabine and Francis, Ziad and Grichine, Vladimir and Gumplinger, Peter and Gueye, Paul and Incerti, Sebastien and Ivanchenko, Anton and Jacquemier, Jean and Lechner, Anton and Longo, Francesco and Kadri, Omrane and Karakatsanis, Nicolas and Karamitros, Mathieu and Kokoulin, Rostislav and Kurashige, Hisaya and Maire, Michel and Mantero, Alfonso and Mascialino, Barbara and Moscicki, Jakub and Pandola, Luciano and Perl, Joseph and Petrović, Ivan M. and Ristić-Fira, Aleksandra and Romano, Francesco and Russo, Giorgio and Santin, Giovanni and Schaelicke, Andreas and Toshito, Toshiyuki and Tran, Hoang and Urban, Laszlo and Yamashita, Tomohiro and Zacharatou, Christina",
year = "2011",
url = "http://inis.iaea.org/search/search.aspx?orig_q=RN:49057834, http://www.aesj.or.jp/publication/pnst002/data/898-903.pdf, http://vinar.vin.bg.ac.rs/handle/123456789/8641",
abstract = "An overview of the electromagnetic (EM) physics of the Geant4 toolkit is presented Two sets of EM models are available: the 'Standard' initially focused on high energy physics (HEP) while the 'Low-energy' was developed for medical, space and other applications The 'Standard' models provide a faster computation but are less accurate for keV energies, the 'Low-energy' models are more CPU time consuming A common interface to EM physics models has been developed allowing a natural combination of ultra-relativistic, relativistic and low-energy models for the same run providing both precision and CPU performance Due to this migration additional capabilities become available The new developments include relativistic models for bremsstrahlung and e+e- pair production, models of multiple and single scattering, hadron/ion ionization, microdosimetry for very low energies and also improvements in existing Geant4 models In parallel, validation suites and benchmarks have been intensively developed (author)",
journal = "Progress in Nuclear Science and Technology",
title = "Recent Improvements in Geant4 Electromagnetic Physics Models and Interfaces",
volume = "2",
pages = "898-903",
doi = "10.15669/pnst.2.898"
}
Ivanchenko, V., Apostolakis, J., Bagulya, A., Abdelouahed, H. B., Black, R., Bogdanov, A., Burkhard, H., Chauvie, S., Cirrone, G. A. P., Cuttone, G., Depaola, G., Di Rosa, F., Elles, S., Francis, Z., Grichine, V., Gumplinger, P., Gueye, P., Incerti, S., Ivanchenko, A., Jacquemier, J., Lechner, A., Longo, F., Kadri, O., Karakatsanis, N., Karamitros, M., Kokoulin, R., Kurashige, H., Maire, M., Mantero, A., Mascialino, B., Moscicki, J., Pandola, L., Perl, J., Petrović, I. M., Ristić-Fira, A., Romano, F., Russo, G., Santin, G., Schaelicke, A., Toshito, T., Tran, H., Urban, L., Yamashita, T.,& Zacharatou, C. (2011). Recent Improvements in Geant4 Electromagnetic Physics Models and Interfaces.
Progress in Nuclear Science and Technology, 2, 898-903.
https://doi.org/10.15669/pnst.2.898
Ivanchenko V, Apostolakis J, Bagulya A, Abdelouahed HB, Black R, Bogdanov A, Burkhard H, Chauvie S, Cirrone GAP, Cuttone G, Depaola G, Di Rosa F, Elles S, Francis Z, Grichine V, Gumplinger P, Gueye P, Incerti S, Ivanchenko A, Jacquemier J, Lechner A, Longo F, Kadri O, Karakatsanis N, Karamitros M, Kokoulin R, Kurashige H, Maire M, Mantero A, Mascialino B, Moscicki J, Pandola L, Perl J, Petrović IM, Ristić-Fira A, Romano F, Russo G, Santin G, Schaelicke A, Toshito T, Tran H, Urban L, Yamashita T, Zacharatou C. Recent Improvements in Geant4 Electromagnetic Physics Models and Interfaces. Progress in Nuclear Science and Technology. 2011;2:898-903
Ivanchenko Vladimir, Apostolakis John, Bagulya Alexander, Abdelouahed Haifa Ben, Black Rachel, Bogdanov Alexey, Burkhard Helmut, Chauvie Stéphane, Cirrone Giuseppe Antonio Pablo, Cuttone Giacomo, Depaola Gerardo, Di Rosa Francesco, Elles Sabine, Francis Ziad, Grichine Vladimir, Gumplinger Peter, Gueye Paul, Incerti Sebastien, Ivanchenko Anton, Jacquemier Jean, Lechner Anton, Longo Francesco, Kadri Omrane, Karakatsanis Nicolas, Karamitros Mathieu, Kokoulin Rostislav, Kurashige Hisaya, Maire Michel, Mantero Alfonso, Mascialino Barbara, Moscicki Jakub, Pandola Luciano, Perl Joseph, Petrović Ivan M., Ristić-Fira Aleksandra, Romano Francesco, Russo Giorgio, Santin Giovanni, Schaelicke Andreas, Toshito Toshiyuki, Tran Hoang, Urban Laszlo, Yamashita Tomohiro, Zacharatou Christina, "Recent Improvements in Geant4 Electromagnetic Physics Models and Interfaces" Progress in Nuclear Science and Technology, 2 (2011):898-903,
https://doi.org/10.15669/pnst.2.898 .
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