TY  - CONF
AU  - Nešić, M.
AU  - Popović, M.
AU  - Galović, Slobodanka
AU  - Miletić, V.
AU  - Kostić, Lj.
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/11819
AB  - In transmission gas-microphone photoacoustics, in order to protect the microphone and improve the Signal to Noise Ratio of the experiment, a thin non-transparent layer is applied on the surface of the sample. When the applied layer is not illuminated – the incident light is passed through the sample, instead, and all the transmitted radiation is absorbed at the non-illuminated side of the system – optical absorption properties of the sample are preserved in the recorded photoacoustic response [1-3]. Thermoelastic component of photoacoustic response is based on the integral of temperature distribution in the sample. However, in the described configuration, the amplitude ratio and the phase difference of surface temperature variations can notably influence the direction and the intensity of the thermoelastic movement of the sample, thus modifying the induced photoacoustic response. Herein, the analysis of surface temperature variations is done, aimed at the prediction of thermoelastic component of the induced photoacoustic response, and the sensitivity of the described model to the alterations of optical absorption coefficient is analyzed and discussed.
PB  - Belgrade : Vinča Institute of Nuclear Sciences
C3  - PHOTONICA2023 : 9th International School and Conference on Photonics : book of abstracts; August 28 - September 1, 2023; Belgrade
T1  - The analysis of the influence of optical absorbance on photothermally induced surface temperature variations in a thin sample of high optical transparence
SP  - 123
EP  - 123
UR  - https://hdl.handle.net/21.15107/rcub_vinar_11819
ER  - 

@conference{
author = "Nešić, M. and Popović, M. and Galović, Slobodanka and Miletić, V. and Kostić, Lj.",
year = "2023",
abstract = "In transmission gas-microphone photoacoustics, in order to protect the microphone and improve the Signal to Noise Ratio of the experiment, a thin non-transparent layer is applied on the surface of the sample. When the applied layer is not illuminated – the incident light is passed through the sample, instead, and all the transmitted radiation is absorbed at the non-illuminated side of the system – optical absorption properties of the sample are preserved in the recorded photoacoustic response [1-3]. Thermoelastic component of photoacoustic response is based on the integral of temperature distribution in the sample. However, in the described configuration, the amplitude ratio and the phase difference of surface temperature variations can notably influence the direction and the intensity of the thermoelastic movement of the sample, thus modifying the induced photoacoustic response. Herein, the analysis of surface temperature variations is done, aimed at the prediction of thermoelastic component of the induced photoacoustic response, and the sensitivity of the described model to the alterations of optical absorption coefficient is analyzed and discussed.",
publisher = "Belgrade : Vinča Institute of Nuclear Sciences",
journal = "PHOTONICA2023 : 9th International School and Conference on Photonics : book of abstracts; August 28 - September 1, 2023; Belgrade",
title = "The analysis of the influence of optical absorbance on photothermally induced surface temperature variations in a thin sample of high optical transparence",
pages = "123-123",
url = "https://hdl.handle.net/21.15107/rcub_vinar_11819"
}

Nešić, M., Popović, M., Galović, S., Miletić, V.,& Kostić, Lj.. (2023). The analysis of the influence of optical absorbance on photothermally induced surface temperature variations in a thin sample of high optical transparence. in PHOTONICA2023 : 9th International School and Conference on Photonics : book of abstracts; August 28 - September 1, 2023; Belgrade
Belgrade : Vinča Institute of Nuclear Sciences., 123-123.
https://hdl.handle.net/21.15107/rcub_vinar_11819

Nešić M, Popović M, Galović S, Miletić V, Kostić L. The analysis of the influence of optical absorbance on photothermally induced surface temperature variations in a thin sample of high optical transparence. in PHOTONICA2023 : 9th International School and Conference on Photonics : book of abstracts; August 28 - September 1, 2023; Belgrade. 2023;:123-123.
https://hdl.handle.net/21.15107/rcub_vinar_11819 .

Nešić, M., Popović, M., Galović, Slobodanka, Miletić, V., Kostić, Lj., "The analysis of the influence of optical absorbance on photothermally induced surface temperature variations in a thin sample of high optical transparence" in PHOTONICA2023 : 9th International School and Conference on Photonics : book of abstracts; August 28 - September 1, 2023; Belgrade (2023):123-123,
https://hdl.handle.net/21.15107/rcub_vinar_11819 .

TY  - CONF
AU  - Popović, I.
AU  - Valenta Šobot, Ana
AU  - Filipović Tričković, Jelena
AU  - Korićanac, Lela
AU  - Žakula, Jelena
AU  - Ralić, V.
AU  - Abu el Rub, Anamarija
AU  - Algarra, M.
AU  - Petković, M.
AU  - Stepić, Milutin
AU  - Nešić, M.
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/11808
AB  - In recent years researchers have developed new strategies to enhance the effectiveness of wound healing by combining nanoparticles and infra red (IR) light. For example, some studies have shown that nanoparticles can be used to enhance the absorption of near-infrared laser (NIR) light by tissues, leading to increased healing rates [1]. The influence of NIR light on proliferation, collagen production, and wound healing was tested on: keratocytes (HaCaT) and fibroblasts (MRC-5) cells that are used as model systems of human skin equivalents that comprise an epidermal and a dermal compartment of skin. Also, these cells were treated with carbon quantum dots/silver-based metal-organic framework composites (Ag-MoFs-NCDs and Ag-MoFs-SCDs), which previously showed high antibacterial activity [2], without and with laser light. Firstly, we have found the most convenient and effective CW laser intensity (16 mW/cm2) and illumination time (3 minutes), which is not too high and short enough to influence human cells' proliferation and metabolism positively. Additional chemical treatment with Ag-MoFs-NCDs and Ag-MoFs-SCDs results in a further increase in human cell viability. Our measurements showed that the proliferation index in laser-illuminated cells and cells treated with Ag-MoFs-SCDs was at the level of the untreated control. Furthermore, Ag-MoFs-SCDs treatment and laser illumination induced a mild, insignificant increase in cellular proliferation. On the other hand, Ag-MoFs-NCDs treatment led to a more pronounced, albeit not significant increase, in cellular proliferation, while Ag-MoFs-NCDs treatment combined with laser illumination significantly increased proliferation. Also, we have detected a mild change in collagen level estimated by hydroxyproline assay, which may indicate a positive outcome of combined laser illumination and treatment, taking into account that after 48 hours, a change in cell's response to the treatment could be noticed. Finally, based on migration assay, we observe a complete wound closure after 48 hours in fibroblast cells treated with Ag-MoFs-NCDs and near-infrared laser light, Fig. 1.
PB  - Belgrade : Vinča Institute of Nuclear Sciences
C3  - PHOTONICA2023 : 9th International School and Conference on Photonics : book of abstracts; August 28 - September 1, 2023; Belgrade
T1  - Carbon quantum dots/silver based metal organic framework composites in light enhanced wound healing
SP  - 78
EP  - 78
UR  - https://hdl.handle.net/21.15107/rcub_vinar_11808
ER  - 

@conference{
author = "Popović, I. and Valenta Šobot, Ana and Filipović Tričković, Jelena and Korićanac, Lela and Žakula, Jelena and Ralić, V. and Abu el Rub, Anamarija and Algarra, M. and Petković, M. and Stepić, Milutin and Nešić, M.",
year = "2023",
abstract = "In recent years researchers have developed new strategies to enhance the effectiveness of wound healing by combining nanoparticles and infra red (IR) light. For example, some studies have shown that nanoparticles can be used to enhance the absorption of near-infrared laser (NIR) light by tissues, leading to increased healing rates [1]. The influence of NIR light on proliferation, collagen production, and wound healing was tested on: keratocytes (HaCaT) and fibroblasts (MRC-5) cells that are used as model systems of human skin equivalents that comprise an epidermal and a dermal compartment of skin. Also, these cells were treated with carbon quantum dots/silver-based metal-organic framework composites (Ag-MoFs-NCDs and Ag-MoFs-SCDs), which previously showed high antibacterial activity [2], without and with laser light. Firstly, we have found the most convenient and effective CW laser intensity (16 mW/cm2) and illumination time (3 minutes), which is not too high and short enough to influence human cells' proliferation and metabolism positively. Additional chemical treatment with Ag-MoFs-NCDs and Ag-MoFs-SCDs results in a further increase in human cell viability. Our measurements showed that the proliferation index in laser-illuminated cells and cells treated with Ag-MoFs-SCDs was at the level of the untreated control. Furthermore, Ag-MoFs-SCDs treatment and laser illumination induced a mild, insignificant increase in cellular proliferation. On the other hand, Ag-MoFs-NCDs treatment led to a more pronounced, albeit not significant increase, in cellular proliferation, while Ag-MoFs-NCDs treatment combined with laser illumination significantly increased proliferation. Also, we have detected a mild change in collagen level estimated by hydroxyproline assay, which may indicate a positive outcome of combined laser illumination and treatment, taking into account that after 48 hours, a change in cell's response to the treatment could be noticed. Finally, based on migration assay, we observe a complete wound closure after 48 hours in fibroblast cells treated with Ag-MoFs-NCDs and near-infrared laser light, Fig. 1.",
publisher = "Belgrade : Vinča Institute of Nuclear Sciences",
journal = "PHOTONICA2023 : 9th International School and Conference on Photonics : book of abstracts; August 28 - September 1, 2023; Belgrade",
title = "Carbon quantum dots/silver based metal organic framework composites in light enhanced wound healing",
pages = "78-78",
url = "https://hdl.handle.net/21.15107/rcub_vinar_11808"
}

Popović, I., Valenta Šobot, A., Filipović Tričković, J., Korićanac, L., Žakula, J., Ralić, V., Abu el Rub, A., Algarra, M., Petković, M., Stepić, M.,& Nešić, M.. (2023). Carbon quantum dots/silver based metal organic framework composites in light enhanced wound healing. in PHOTONICA2023 : 9th International School and Conference on Photonics : book of abstracts; August 28 - September 1, 2023; Belgrade
Belgrade : Vinča Institute of Nuclear Sciences., 78-78.
https://hdl.handle.net/21.15107/rcub_vinar_11808

Popović I, Valenta Šobot A, Filipović Tričković J, Korićanac L, Žakula J, Ralić V, Abu el Rub A, Algarra M, Petković M, Stepić M, Nešić M. Carbon quantum dots/silver based metal organic framework composites in light enhanced wound healing. in PHOTONICA2023 : 9th International School and Conference on Photonics : book of abstracts; August 28 - September 1, 2023; Belgrade. 2023;:78-78.
https://hdl.handle.net/21.15107/rcub_vinar_11808 .

Popović, I., Valenta Šobot, Ana, Filipović Tričković, Jelena, Korićanac, Lela, Žakula, Jelena, Ralić, V., Abu el Rub, Anamarija, Algarra, M., Petković, M., Stepić, Milutin, Nešić, M., "Carbon quantum dots/silver based metal organic framework composites in light enhanced wound healing" in PHOTONICA2023 : 9th International School and Conference on Photonics : book of abstracts; August 28 - September 1, 2023; Belgrade (2023):78-78,
https://hdl.handle.net/21.15107/rcub_vinar_11808 .