TY  - JOUR
AU  - Mijajlović, Marina Ž.
AU  - Nikolić, Miloš V.
AU  - Jevtić, Verica V.
AU  - Ratković, Zoran R.
AU  - Milovanović, Jelena
AU  - Arsenijević, Aleksandar
AU  - Stojanović, Bojana
AU  - Novaković, Slađana B.
AU  - Bogdanović, Goran A.
AU  - Trifunović, Srećko R.
AU  - Radić, Gordana P.
PY  - 2016
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/1166
AB  - The syntheses of tetradentate ligand, meso-1,2-diphenyl-ethylenediamine-N,N-di-3-propanoic acid (H-2-1,2-dpheddp) and corresponding platinum(IV) and palladium(II) complexes are reported here. The spectroscopically predicted structure of the obtained palladium(II) complex was confirmed by X-ray analysis. Singe crystals suitable for X-ray measurements were obtained by slow crystallization from a DMSO-water mixture. Cytotoxic effects of platinum(IV), palladium(II) complexes and cisplatin on the 4T1 and Bl6F1 cell lines were determined using the MTT colorimetric technique. The complexes showed a dose dependence on cytotoxic effect toward both cell lines. Both complexes were less active than cisplatin, the exception was concentrations above 62.5 mu M of platinum(IV) complex in the B16F1 cell line.
T2  - Macedonian Journal of Chemistry and Chemical Engineering
T1  - Cytotoxicity of Platinum(Iv) and Palladium(Ii) Complexes with Meso-1,2-Diphenyl-Ethylenediamine-N,N -Di-3-Propanoic Acid. Crystal Structure of [Pd(1,2-Dpheddp)] Complex
VL  - 35
IS  - 1
SP  - 79
EP  - 86
DO  - 10.20450/mjcce.2016.729
ER  - 

@article{
author = "Mijajlović, Marina Ž. and Nikolić, Miloš V. and Jevtić, Verica V. and Ratković, Zoran R. and Milovanović, Jelena and Arsenijević, Aleksandar and Stojanović, Bojana and Novaković, Slađana B. and Bogdanović, Goran A. and Trifunović, Srećko R. and Radić, Gordana P.",
year = "2016",
abstract = "The syntheses of tetradentate ligand, meso-1,2-diphenyl-ethylenediamine-N,N-di-3-propanoic acid (H-2-1,2-dpheddp) and corresponding platinum(IV) and palladium(II) complexes are reported here. The spectroscopically predicted structure of the obtained palladium(II) complex was confirmed by X-ray analysis. Singe crystals suitable for X-ray measurements were obtained by slow crystallization from a DMSO-water mixture. Cytotoxic effects of platinum(IV), palladium(II) complexes and cisplatin on the 4T1 and Bl6F1 cell lines were determined using the MTT colorimetric technique. The complexes showed a dose dependence on cytotoxic effect toward both cell lines. Both complexes were less active than cisplatin, the exception was concentrations above 62.5 mu M of platinum(IV) complex in the B16F1 cell line.",
journal = "Macedonian Journal of Chemistry and Chemical Engineering",
title = "Cytotoxicity of Platinum(Iv) and Palladium(Ii) Complexes with Meso-1,2-Diphenyl-Ethylenediamine-N,N -Di-3-Propanoic Acid. Crystal Structure of [Pd(1,2-Dpheddp)] Complex",
volume = "35",
number = "1",
pages = "79-86",
doi = "10.20450/mjcce.2016.729"
}

Mijajlović, M. Ž., Nikolić, M. V., Jevtić, V. V., Ratković, Z. R., Milovanović, J., Arsenijević, A., Stojanović, B., Novaković, S. B., Bogdanović, G. A., Trifunović, S. R.,& Radić, G. P.. (2016). Cytotoxicity of Platinum(Iv) and Palladium(Ii) Complexes with Meso-1,2-Diphenyl-Ethylenediamine-N,N -Di-3-Propanoic Acid. Crystal Structure of [Pd(1,2-Dpheddp)] Complex. in Macedonian Journal of Chemistry and Chemical Engineering, 35(1), 79-86.
https://doi.org/10.20450/mjcce.2016.729

Mijajlović MŽ, Nikolić MV, Jevtić VV, Ratković ZR, Milovanović J, Arsenijević A, Stojanović B, Novaković SB, Bogdanović GA, Trifunović SR, Radić GP. Cytotoxicity of Platinum(Iv) and Palladium(Ii) Complexes with Meso-1,2-Diphenyl-Ethylenediamine-N,N -Di-3-Propanoic Acid. Crystal Structure of [Pd(1,2-Dpheddp)] Complex. in Macedonian Journal of Chemistry and Chemical Engineering. 2016;35(1):79-86.
doi:10.20450/mjcce.2016.729 .

Mijajlović, Marina Ž., Nikolić, Miloš V., Jevtić, Verica V., Ratković, Zoran R., Milovanović, Jelena, Arsenijević, Aleksandar, Stojanović, Bojana, Novaković, Slađana B., Bogdanović, Goran A., Trifunović, Srećko R., Radić, Gordana P., "Cytotoxicity of Platinum(Iv) and Palladium(Ii) Complexes with Meso-1,2-Diphenyl-Ethylenediamine-N,N -Di-3-Propanoic Acid. Crystal Structure of [Pd(1,2-Dpheddp)] Complex" in Macedonian Journal of Chemistry and Chemical Engineering, 35, no. 1 (2016):79-86,
https://doi.org/10.20450/mjcce.2016.729 . .

TY  - JOUR
AU  - Nikolić, Miloš V.
AU  - Mijajlović, Marina Ž.
AU  - Jevtić, Verica V.
AU  - Ratković, Zoran R.
AU  - Novaković, Slađana B.
AU  - Bogdanović, Goran A.
AU  - Milovanović, Jelena
AU  - Arsenijević, Aleksandar
AU  - Stojanović, Bojana
AU  - Trifunović, Srećko R.
AU  - Radić, Gordana P.
PY  - 2016
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/1068
AB  - The spectroscopically predicted structure of the obtained copper(II)-complex with S-ethyl derivative of thiosalicylic acid was confirmed by X-ray structural study and compared to previously reported crystal structure of the Cu complex with S-methyl derivative. Single crystals suitable for X-ray measurements were obtained by slow crystallization from a water solution. Cytotoxic effects of S-alkyl (R = benzyl (L1), methyl (12), ethyl (L3), propyl (IA) and butyl (L5)) derivatives of thiosalicylic acid and the corresponding binuclear copper(II)-complexes on murine colon carcinoma cell lines, 026 and CT26.CL25 and human colon carcinoma cell line HCT-116 were reported here. The analysis of cancer cell viability showed that all the tested complexes had low cytotoxic effect on murine colon carcinoma cell lines, but several times higher cytotoxicity on normal human colon carcinoma cells. (C) 2016 Elsevier B.V. All rights reserved.
PB  - Elsevier
T2  - Journal of Molecular Structure
T1  - Cytotoxicity of copper(II)-complexes with some S-alkyl derivatives of thiosalicylic acid. Crystal structure of the binuclear copper(II)-complex with S-ethyl derivative of thiosalicylic acid
VL  - 1116
SP  - 264
EP  - 271
DO  - 10.1016/j.molstruc.2016.03.058
ER  - 

@article{
author = "Nikolić, Miloš V. and Mijajlović, Marina Ž. and Jevtić, Verica V. and Ratković, Zoran R. and Novaković, Slađana B. and Bogdanović, Goran A. and Milovanović, Jelena and Arsenijević, Aleksandar and Stojanović, Bojana and Trifunović, Srećko R. and Radić, Gordana P.",
year = "2016",
abstract = "The spectroscopically predicted structure of the obtained copper(II)-complex with S-ethyl derivative of thiosalicylic acid was confirmed by X-ray structural study and compared to previously reported crystal structure of the Cu complex with S-methyl derivative. Single crystals suitable for X-ray measurements were obtained by slow crystallization from a water solution. Cytotoxic effects of S-alkyl (R = benzyl (L1), methyl (12), ethyl (L3), propyl (IA) and butyl (L5)) derivatives of thiosalicylic acid and the corresponding binuclear copper(II)-complexes on murine colon carcinoma cell lines, 026 and CT26.CL25 and human colon carcinoma cell line HCT-116 were reported here. The analysis of cancer cell viability showed that all the tested complexes had low cytotoxic effect on murine colon carcinoma cell lines, but several times higher cytotoxicity on normal human colon carcinoma cells. (C) 2016 Elsevier B.V. All rights reserved.",
publisher = "Elsevier",
journal = "Journal of Molecular Structure",
title = "Cytotoxicity of copper(II)-complexes with some S-alkyl derivatives of thiosalicylic acid. Crystal structure of the binuclear copper(II)-complex with S-ethyl derivative of thiosalicylic acid",
volume = "1116",
pages = "264-271",
doi = "10.1016/j.molstruc.2016.03.058"
}

Nikolić, M. V., Mijajlović, M. Ž., Jevtić, V. V., Ratković, Z. R., Novaković, S. B., Bogdanović, G. A., Milovanović, J., Arsenijević, A., Stojanović, B., Trifunović, S. R.,& Radić, G. P.. (2016). Cytotoxicity of copper(II)-complexes with some S-alkyl derivatives of thiosalicylic acid. Crystal structure of the binuclear copper(II)-complex with S-ethyl derivative of thiosalicylic acid. in Journal of Molecular Structure
Elsevier., 1116, 264-271.
https://doi.org/10.1016/j.molstruc.2016.03.058

Nikolić MV, Mijajlović MŽ, Jevtić VV, Ratković ZR, Novaković SB, Bogdanović GA, Milovanović J, Arsenijević A, Stojanović B, Trifunović SR, Radić GP. Cytotoxicity of copper(II)-complexes with some S-alkyl derivatives of thiosalicylic acid. Crystal structure of the binuclear copper(II)-complex with S-ethyl derivative of thiosalicylic acid. in Journal of Molecular Structure. 2016;1116:264-271.
doi:10.1016/j.molstruc.2016.03.058 .

Nikolić, Miloš V., Mijajlović, Marina Ž., Jevtić, Verica V., Ratković, Zoran R., Novaković, Slađana B., Bogdanović, Goran A., Milovanović, Jelena, Arsenijević, Aleksandar, Stojanović, Bojana, Trifunović, Srećko R., Radić, Gordana P., "Cytotoxicity of copper(II)-complexes with some S-alkyl derivatives of thiosalicylic acid. Crystal structure of the binuclear copper(II)-complex with S-ethyl derivative of thiosalicylic acid" in Journal of Molecular Structure, 1116 (2016):264-271,
https://doi.org/10.1016/j.molstruc.2016.03.058 . .