TY  - JOUR
AU  - Motorzhina, Anna V.
AU  - Pshenichnikov, Stanislav E.
AU  - Anikin, Anton A.
AU  - Belyaev, Victor K.
AU  - Yakunin, Alexander N.
AU  - Zarkov, Sergey V.
AU  - Tuchin, Valery V.
AU  - Jovanović, Sonja
AU  - Sangregorio, Claudio
AU  - Rodionova, Valeria V.
AU  - Panina, Larissa V.
AU  - Levada, Kateryna V.
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/13391
AB  - The study encompasses an investigationof optical, photothermal and biocom-patibility properties of a composite con-sisting of golden cores surrounded bysuperparamagnetic CoFe 2 O 4 nanoparti-cles. Accompanied with the experiment,the computational modeling reveals that each adjusted magnetic nanoparticleredshifts the plasmon resonance frequency in gold and nonlinearly increases theextinction cross-section at 800 nm. The concentration dependent photothermalstudy demonstrates a temperature increase of 8.2 K and the photothermal con-version efficiency of 51% for the 100 μg/mL aqueous solution of the compositenanoparticles, when subjected to a laser power of 0.5 W at 815 nm. During anin vitro photothermal therapy, a portion of the composite nanoparticles, initiallyseeded at this concentration, remained associated with the cells after washing.These retained nanoparticles effectively heated the cell culture medium, result-ing in a 22% reduction in cell viability after 15 min of the treatment. The com-posite features a potential in multimodal magneto-plasmonic therapies.
T2  - Journal of Biophotonics
T1  - Gold/cobalt ferrite nanocomposite as a potential agent for photothermal therapy
DO  - 10.1002/jbio.202300475
ER  - 

@article{
author = "Motorzhina, Anna V. and Pshenichnikov, Stanislav E. and Anikin, Anton A. and Belyaev, Victor K. and Yakunin, Alexander N. and Zarkov, Sergey V. and Tuchin, Valery V. and Jovanović, Sonja and Sangregorio, Claudio and Rodionova, Valeria V. and Panina, Larissa V. and Levada, Kateryna V.",
year = "2024",
abstract = "The study encompasses an investigationof optical, photothermal and biocom-patibility properties of a composite con-sisting of golden cores surrounded bysuperparamagnetic CoFe 2 O 4 nanoparti-cles. Accompanied with the experiment,the computational modeling reveals that each adjusted magnetic nanoparticleredshifts the plasmon resonance frequency in gold and nonlinearly increases theextinction cross-section at 800 nm. The concentration dependent photothermalstudy demonstrates a temperature increase of 8.2 K and the photothermal con-version efficiency of 51% for the 100 μg/mL aqueous solution of the compositenanoparticles, when subjected to a laser power of 0.5 W at 815 nm. During anin vitro photothermal therapy, a portion of the composite nanoparticles, initiallyseeded at this concentration, remained associated with the cells after washing.These retained nanoparticles effectively heated the cell culture medium, result-ing in a 22% reduction in cell viability after 15 min of the treatment. The com-posite features a potential in multimodal magneto-plasmonic therapies.",
journal = "Journal of Biophotonics",
title = "Gold/cobalt ferrite nanocomposite as a potential agent for photothermal therapy",
doi = "10.1002/jbio.202300475"
}

Motorzhina, A. V., Pshenichnikov, S. E., Anikin, A. A., Belyaev, V. K., Yakunin, A. N., Zarkov, S. V., Tuchin, V. V., Jovanović, S., Sangregorio, C., Rodionova, V. V., Panina, L. V.,& Levada, K. V.. (2024). Gold/cobalt ferrite nanocomposite as a potential agent for photothermal therapy. in Journal of Biophotonics.
https://doi.org/10.1002/jbio.202300475

Motorzhina AV, Pshenichnikov SE, Anikin AA, Belyaev VK, Yakunin AN, Zarkov SV, Tuchin VV, Jovanović S, Sangregorio C, Rodionova VV, Panina LV, Levada KV. Gold/cobalt ferrite nanocomposite as a potential agent for photothermal therapy. in Journal of Biophotonics. 2024;.
doi:10.1002/jbio.202300475 .

Motorzhina, Anna V., Pshenichnikov, Stanislav E., Anikin, Anton A., Belyaev, Victor K., Yakunin, Alexander N., Zarkov, Sergey V., Tuchin, Valery V., Jovanović, Sonja, Sangregorio, Claudio, Rodionova, Valeria V., Panina, Larissa V., Levada, Kateryna V., "Gold/cobalt ferrite nanocomposite as a potential agent for photothermal therapy" in Journal of Biophotonics (2024),
https://doi.org/10.1002/jbio.202300475 . .

TY  - JOUR
AU  - Motorzhina, Anna V.
AU  - Belyaev, Victor
AU  - Kolesnikova, Valeria
AU  - Jovanović, Sonja
AU  - Panina, Larissa V.
AU  - Levada, Kateryna
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10408
AB  - The rapid development of the nanomaterials’ application’s fields in biomedicine is associated with the expanded possibilities of combining their properties in composite materials. The use of nanocomposites allows application in various types of therapy or theranostics. In this work, we propose a new approach for the fabrication of a gold/ferrite nanocomposite, which consists of gold particles up to 10 nm in diameter surrounded by small nanoparticles of cobalt ferrite (~5 nm) doped with zinc. The gold core is coated with arginine, while the ferrite particles have dihydrocaffeic acid shell. The fabricated nanocomposite possesses optical and magnetic properties due to the excitation of localized plasmon resonance in gold particles and the superparamagnetic state of ferrite particles. The results of studying the structural, magnetic, and optical properties, as well as the cytotoxicity of the obtained nanocomposite, allow us to conclude that it can be used in combined photo- and magnetic hyperthermic therapy.
T2  - Nanobiotechnology Reports
T1  - Zinc-Doped Gold/Cobalt Ferrite Nanoparticles in Studying the Cytotoxic Effect on T-Lymphoblastic Leukemia Cells
VL  - 17
IS  - 3
SP  - 436
EP  - 443
DO  - 10.1134/S2635167622030120
DO  - 10.1134/S2635167622030120
ER  - 

@article{
author = "Motorzhina, Anna V. and Belyaev, Victor and Kolesnikova, Valeria and Jovanović, Sonja and Panina, Larissa V. and Levada, Kateryna",
year = "2022",
abstract = "The rapid development of the nanomaterials’ application’s fields in biomedicine is associated with the expanded possibilities of combining their properties in composite materials. The use of nanocomposites allows application in various types of therapy or theranostics. In this work, we propose a new approach for the fabrication of a gold/ferrite nanocomposite, which consists of gold particles up to 10 nm in diameter surrounded by small nanoparticles of cobalt ferrite (~5 nm) doped with zinc. The gold core is coated with arginine, while the ferrite particles have dihydrocaffeic acid shell. The fabricated nanocomposite possesses optical and magnetic properties due to the excitation of localized plasmon resonance in gold particles and the superparamagnetic state of ferrite particles. The results of studying the structural, magnetic, and optical properties, as well as the cytotoxicity of the obtained nanocomposite, allow us to conclude that it can be used in combined photo- and magnetic hyperthermic therapy.",
journal = "Nanobiotechnology Reports",
title = "Zinc-Doped Gold/Cobalt Ferrite Nanoparticles in Studying the Cytotoxic Effect on T-Lymphoblastic Leukemia Cells",
volume = "17",
number = "3",
pages = "436-443",
doi = "10.1134/S2635167622030120, 10.1134/S2635167622030120"
}

Motorzhina, A. V., Belyaev, V., Kolesnikova, V., Jovanović, S., Panina, L. V.,& Levada, K.. (2022). Zinc-Doped Gold/Cobalt Ferrite Nanoparticles in Studying the Cytotoxic Effect on T-Lymphoblastic Leukemia Cells. in Nanobiotechnology Reports, 17(3), 436-443.
https://doi.org/10.1134/S2635167622030120

Motorzhina AV, Belyaev V, Kolesnikova V, Jovanović S, Panina LV, Levada K. Zinc-Doped Gold/Cobalt Ferrite Nanoparticles in Studying the Cytotoxic Effect on T-Lymphoblastic Leukemia Cells. in Nanobiotechnology Reports. 2022;17(3):436-443.
doi:10.1134/S2635167622030120 .

Motorzhina, Anna V., Belyaev, Victor, Kolesnikova, Valeria, Jovanović, Sonja, Panina, Larissa V., Levada, Kateryna, "Zinc-Doped Gold/Cobalt Ferrite Nanoparticles in Studying the Cytotoxic Effect on T-Lymphoblastic Leukemia Cells" in Nanobiotechnology Reports, 17, no. 3 (2022):436-443,
https://doi.org/10.1134/S2635167622030120 . .