Stančov, Danijela

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orcid::0000-0003-1260-4314
  • Stančov, Danijela (2)
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Author's Bibliography

Quality control in radiation processing in the Vinča Institute Radiation Plant: Case study

Šećerov, Bojana; Stančov, Danijela; Radenković, Mirjana; Dramićanin, Miroslav

(2016)

TY  - JOUR
AU  - Šećerov, Bojana
AU  - Stančov, Danijela
AU  - Radenković, Mirjana
AU  - Dramićanin, Miroslav
PY  - 2016
UR  - http://casopisi.junis.ni.ac.rs/index.php/FUPhysChemTech/article/view/1535
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/7627
AB  - The irradiation process control has to define facility parameters, validation of product and routine control of the irradiation process during exploitation. To meet the regulations, it is necessary to stop the exploitation and do the qualification exercises after changes in the source loading, source geometry or product transport system. In order to save time, the new combined approach has been analyzed for qualification of sterilization process used in the Vinča Institute Radiation Plant. The absorbed dose is calculated assuming that the irradiation process runs with specified parameters. The results of absorbed dose measurements in an experiment done during the sterilization process were used for dose calculations. The calculated absorbed doses are compared with measured ones. The criterion for a positive qualification is the superposition of calculated and measured values. Two different types of dosimeters are used for measurements: ethanol-chlorobenzene and alanine. The measurement traceability is achieved through the calibration by the Riso National Laboratory, Denmark. In this case study, the determined dwell time for target dose is 450s. 1.23 is dose uniformity ratio in the box with plastic products with dose minimum at the bottom corners in the center and dose maximum at the top of the surface plane of the box parallel to the source. The calculated and measured absorbed doses show the same difference of 13% between the surface and the central plane in the box. The dose reproducibility for irradiation process is 3.5%.
AB  - Kontrola procesa ozračivanja mora da definiše parametre postrojenja, validaciju proizvoda i rutinsku kontrolu procesa tokom eksploatacije. Da bi se ispunili zahteve propisa, neophodno je prekinuti eksploataciju i uraditi kvalifikaciju procesa ozračivanja posle svake dopune izvora, promene geometrije izvora ili transportnog sistema. U cilju uštede vremena, analiziran je novi kombinovani pristup kvalifikacije procesa sterilizacije u Radijacionoj jedinici Instituta 'Vinča'. Apsorbovana doza je izračunavana pretpostavljajući da proces teče po zadatim parametrima. Za izračunavanje koriste se rezultati merenja apsorbovane doze u eksperimentu koji je izveden u toku procesa sterilizacije. Izračunate apsorbovane doze upoređuju se sa izmerenim. Kriterijum za pozitivnu kvalifikaciju procesa je slaganje izračunatih i izmerenih vrednosti. Za merenja su korišćena dva tipa dozimetara: etanol-hlorbenzen i alanin. Merna sledljivost je postignuta preko kalibracije u RISO nacionalnoj laboratoriji u Danskoj. U ovoj studiji, određena je dužina koraka za ciljanu dozu od 450s. 1,23 je odnos homogenosti doze u kutiji sa plastičnim proizvodima, sa minimumom doze u donjim uglovima centralne ravni i maksimalnom dozom na vrhu ivice kutije u ravni paralelnoj sa izvorom. Izračunate i izmerene apsorbovane doze pokazuju istu razliku od 13% između površinske i centralne ravni kutije. Reproduktivnost doze za proces ozračivanja je 3,5%.
T2  - Facta Universitatis, Series: Physics, Chemistry and Technology
T1  - Quality control in radiation processing in the Vinča Institute Radiation Plant: Case study
T1  - Kontrola kvaliteta u tehnologiji obrade zračenjem - studija slučaja Radijacione jedinice u Institutu 'Vinča'
VL  - 14
IS  - 2
SP  - 105
EP  - 113
DO  - 10.2298/FUPCT1602105S
ER  - 
@article{
author = "Šećerov, Bojana and Stančov, Danijela and Radenković, Mirjana and Dramićanin, Miroslav",
year = "2016",
abstract = "The irradiation process control has to define facility parameters, validation of product and routine control of the irradiation process during exploitation. To meet the regulations, it is necessary to stop the exploitation and do the qualification exercises after changes in the source loading, source geometry or product transport system. In order to save time, the new combined approach has been analyzed for qualification of sterilization process used in the Vinča Institute Radiation Plant. The absorbed dose is calculated assuming that the irradiation process runs with specified parameters. The results of absorbed dose measurements in an experiment done during the sterilization process were used for dose calculations. The calculated absorbed doses are compared with measured ones. The criterion for a positive qualification is the superposition of calculated and measured values. Two different types of dosimeters are used for measurements: ethanol-chlorobenzene and alanine. The measurement traceability is achieved through the calibration by the Riso National Laboratory, Denmark. In this case study, the determined dwell time for target dose is 450s. 1.23 is dose uniformity ratio in the box with plastic products with dose minimum at the bottom corners in the center and dose maximum at the top of the surface plane of the box parallel to the source. The calculated and measured absorbed doses show the same difference of 13% between the surface and the central plane in the box. The dose reproducibility for irradiation process is 3.5%., Kontrola procesa ozračivanja mora da definiše parametre postrojenja, validaciju proizvoda i rutinsku kontrolu procesa tokom eksploatacije. Da bi se ispunili zahteve propisa, neophodno je prekinuti eksploataciju i uraditi kvalifikaciju procesa ozračivanja posle svake dopune izvora, promene geometrije izvora ili transportnog sistema. U cilju uštede vremena, analiziran je novi kombinovani pristup kvalifikacije procesa sterilizacije u Radijacionoj jedinici Instituta 'Vinča'. Apsorbovana doza je izračunavana pretpostavljajući da proces teče po zadatim parametrima. Za izračunavanje koriste se rezultati merenja apsorbovane doze u eksperimentu koji je izveden u toku procesa sterilizacije. Izračunate apsorbovane doze upoređuju se sa izmerenim. Kriterijum za pozitivnu kvalifikaciju procesa je slaganje izračunatih i izmerenih vrednosti. Za merenja su korišćena dva tipa dozimetara: etanol-hlorbenzen i alanin. Merna sledljivost je postignuta preko kalibracije u RISO nacionalnoj laboratoriji u Danskoj. U ovoj studiji, određena je dužina koraka za ciljanu dozu od 450s. 1,23 je odnos homogenosti doze u kutiji sa plastičnim proizvodima, sa minimumom doze u donjim uglovima centralne ravni i maksimalnom dozom na vrhu ivice kutije u ravni paralelnoj sa izvorom. Izračunate i izmerene apsorbovane doze pokazuju istu razliku od 13% između površinske i centralne ravni kutije. Reproduktivnost doze za proces ozračivanja je 3,5%.",
journal = "Facta Universitatis, Series: Physics, Chemistry and Technology",
title = "Quality control in radiation processing in the Vinča Institute Radiation Plant: Case study, Kontrola kvaliteta u tehnologiji obrade zračenjem - studija slučaja Radijacione jedinice u Institutu 'Vinča'",
volume = "14",
number = "2",
pages = "105-113",
doi = "10.2298/FUPCT1602105S"
}
Šećerov, B., Stančov, D., Radenković, M.,& Dramićanin, M.. (2016). Quality control in radiation processing in the Vinča Institute Radiation Plant: Case study. in Facta Universitatis, Series: Physics, Chemistry and Technology, 14(2), 105-113.
https://doi.org/10.2298/FUPCT1602105S
Šećerov B, Stančov D, Radenković M, Dramićanin M. Quality control in radiation processing in the Vinča Institute Radiation Plant: Case study. in Facta Universitatis, Series: Physics, Chemistry and Technology. 2016;14(2):105-113.
doi:10.2298/FUPCT1602105S .
Šećerov, Bojana, Stančov, Danijela, Radenković, Mirjana, Dramićanin, Miroslav, "Quality control in radiation processing in the Vinča Institute Radiation Plant: Case study" in Facta Universitatis, Series: Physics, Chemistry and Technology, 14, no. 2 (2016):105-113,
https://doi.org/10.2298/FUPCT1602105S . .

Absorbed dose distribution at Vinča radiation plant

Šećerov, Bojana; Stančov, Danijela

(Society of Physical Chemists of Serbia, 2014)

TY  - CONF
AU  - Šećerov, Bojana
AU  - Stančov, Danijela
PY  - 2014
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9198
AB  - The aim of work is to correlate the absorbed dose distribution and gamma
source activity in Vinča Radiation Plant. The measurements of absorbed
doses obtained during the sterilization process of plastic medical products
are compared with similar measurements made during the commissioning of
this plant, but this time by using alanine dosimetry system. The influence of
source activity to depth dose distribution is as expected, but there is no
effect to the height dose distribution. The inhomogeneity of 13% of the dose
across the box was determined is also done by alanine dosimetry system.
PB  - Society of Physical Chemists of Serbia
C3  - Physical chemistry 2014: 12th International Conference on Fundamental and Applied Aspects of Physical Chemistry
T1  - Absorbed dose distribution at Vinča radiation plant
VL  - G-01-P
UR  - https://hdl.handle.net/21.15107/rcub_vinar_9198
ER  - 
@conference{
author = "Šećerov, Bojana and Stančov, Danijela",
year = "2014",
abstract = "The aim of work is to correlate the absorbed dose distribution and gamma
source activity in Vinča Radiation Plant. The measurements of absorbed
doses obtained during the sterilization process of plastic medical products
are compared with similar measurements made during the commissioning of
this plant, but this time by using alanine dosimetry system. The influence of
source activity to depth dose distribution is as expected, but there is no
effect to the height dose distribution. The inhomogeneity of 13% of the dose
across the box was determined is also done by alanine dosimetry system.",
publisher = "Society of Physical Chemists of Serbia",
journal = "Physical chemistry 2014: 12th International Conference on Fundamental and Applied Aspects of Physical Chemistry",
title = "Absorbed dose distribution at Vinča radiation plant",
volume = "G-01-P",
url = "https://hdl.handle.net/21.15107/rcub_vinar_9198"
}
Šećerov, B.,& Stančov, D.. (2014). Absorbed dose distribution at Vinča radiation plant. in Physical chemistry 2014: 12th International Conference on Fundamental and Applied Aspects of Physical Chemistry
Society of Physical Chemists of Serbia., G-01-P.
https://hdl.handle.net/21.15107/rcub_vinar_9198
Šećerov B, Stančov D. Absorbed dose distribution at Vinča radiation plant. in Physical chemistry 2014: 12th International Conference on Fundamental and Applied Aspects of Physical Chemistry. 2014;G-01-P.
https://hdl.handle.net/21.15107/rcub_vinar_9198 .
Šećerov, Bojana, Stančov, Danijela, "Absorbed dose distribution at Vinča radiation plant" in Physical chemistry 2014: 12th International Conference on Fundamental and Applied Aspects of Physical Chemistry, G-01-P (2014),
https://hdl.handle.net/21.15107/rcub_vinar_9198 .