TY  - JOUR
AU  - Marinković, Jelena
AU  - Marković, Tatjana
AU  - Brkić, Snežana
AU  - Radunović, Milena
AU  - Soldatović, Ivan
AU  - Ćirić, Ana
AU  - Marković, Dejan
PY  - 2020
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10808
AB  - Background/Aim: Understanding the composition of bacteria in infected root canals is important for ameliorating the treatment strategies that lead to the elimination of pathogens and infection control, but also prevent reinfection. Aim of this study was to investigate microbial composition of primary infected root canals with apical periodontitis of young permanent teeth, originating form school children in Serbia, and its association with clinical symptoms. Material and Methods: To determine the bacterial composition of infected root canals in children, 35 endodontic samples were obtained. The identification of cultured bacteria was performed by MALDI-TOF MS analysis. The presence or absence of clinical symptoms were recorded. Results: Facultative anaerobes were 2,2 times more frequent than obligate anaerobes. The most common facultative anaerobes belonged to following genera, Streptococcus (58 isolates), Actinomyces (10) and Enterococcus (8), while predominant obligate anaerobes, belonged to genera Veillonella (15), Prevotella (9) and Fusobacterium (8). The most common clinical isolates recovered from infected root canals with symptomatic apical periodontitis were Veillonella parvula (10) and Fusobacterium nucleatum (7), while from the asymptomatic ones, they were Streptococcus mitis/Streptococcus oralis (5). Prevalence of Parvimonas micra, Prevotella buccae and Streptococcus constellatus within the root canals might be associated to clinical symptoms. Conclusions: Species of genera Streptococcus and Veillonella were the most common isolates from primary infected root canals with apical periodontitis in Serbian school children. Facultative anaerobes were predominant over obligate anaerobes. The prevalence of obligate anaerobes was much higher in symptomatic compared to asymptomatic root canal infections. No specific bacterial strain might be associated to a single examined clinical symptom (pain, tenderness to percussion or swelling), but majority of the strains are associated to all of the examined three symptoms.
T2  - Balkan Journal of Dental Medicine
T1  - Microbiological analysis of primary infected root canals with symptomatic and asymptomatic apical periodontitis of young permanent teeth
VL  - 24
IS  - 3
SP  - 170
EP  - 177
DO  - 10.2478/bjdm-2020-0027
ER  - 

@article{
author = "Marinković, Jelena and Marković, Tatjana and Brkić, Snežana and Radunović, Milena and Soldatović, Ivan and Ćirić, Ana and Marković, Dejan",
year = "2020",
abstract = "Background/Aim: Understanding the composition of bacteria in infected root canals is important for ameliorating the treatment strategies that lead to the elimination of pathogens and infection control, but also prevent reinfection. Aim of this study was to investigate microbial composition of primary infected root canals with apical periodontitis of young permanent teeth, originating form school children in Serbia, and its association with clinical symptoms. Material and Methods: To determine the bacterial composition of infected root canals in children, 35 endodontic samples were obtained. The identification of cultured bacteria was performed by MALDI-TOF MS analysis. The presence or absence of clinical symptoms were recorded. Results: Facultative anaerobes were 2,2 times more frequent than obligate anaerobes. The most common facultative anaerobes belonged to following genera, Streptococcus (58 isolates), Actinomyces (10) and Enterococcus (8), while predominant obligate anaerobes, belonged to genera Veillonella (15), Prevotella (9) and Fusobacterium (8). The most common clinical isolates recovered from infected root canals with symptomatic apical periodontitis were Veillonella parvula (10) and Fusobacterium nucleatum (7), while from the asymptomatic ones, they were Streptococcus mitis/Streptococcus oralis (5). Prevalence of Parvimonas micra, Prevotella buccae and Streptococcus constellatus within the root canals might be associated to clinical symptoms. Conclusions: Species of genera Streptococcus and Veillonella were the most common isolates from primary infected root canals with apical periodontitis in Serbian school children. Facultative anaerobes were predominant over obligate anaerobes. The prevalence of obligate anaerobes was much higher in symptomatic compared to asymptomatic root canal infections. No specific bacterial strain might be associated to a single examined clinical symptom (pain, tenderness to percussion or swelling), but majority of the strains are associated to all of the examined three symptoms.",
journal = "Balkan Journal of Dental Medicine",
title = "Microbiological analysis of primary infected root canals with symptomatic and asymptomatic apical periodontitis of young permanent teeth",
volume = "24",
number = "3",
pages = "170-177",
doi = "10.2478/bjdm-2020-0027"
}

Marinković, J., Marković, T., Brkić, S., Radunović, M., Soldatović, I., Ćirić, A.,& Marković, D.. (2020). Microbiological analysis of primary infected root canals with symptomatic and asymptomatic apical periodontitis of young permanent teeth. in Balkan Journal of Dental Medicine, 24(3), 170-177.
https://doi.org/10.2478/bjdm-2020-0027

Marinković J, Marković T, Brkić S, Radunović M, Soldatović I, Ćirić A, Marković D. Microbiological analysis of primary infected root canals with symptomatic and asymptomatic apical periodontitis of young permanent teeth. in Balkan Journal of Dental Medicine. 2020;24(3):170-177.
doi:10.2478/bjdm-2020-0027 .

Marinković, Jelena, Marković, Tatjana, Brkić, Snežana, Radunović, Milena, Soldatović, Ivan, Ćirić, Ana, Marković, Dejan, "Microbiological analysis of primary infected root canals with symptomatic and asymptomatic apical periodontitis of young permanent teeth" in Balkan Journal of Dental Medicine, 24, no. 3 (2020):170-177,
https://doi.org/10.2478/bjdm-2020-0027 . .