TY  - JOUR
AU  - Petrović, Suzana
AU  - Peruško, Davor
AU  - Mimidis, Alexandros
AU  - Kavatzikidou, Paraskevi
AU  - Kovač, Janez
AU  - Ranella, Anthi
AU  - Novaković, Mirjana M.
AU  - Popović, Maja
AU  - Stratakis, Emmanuel
PY  - 2020
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9785
AB  - Ultrafast laser processing with the formation of periodic surface nanostructures on the 15×(Ti/Zr)/Si multilayers is studied in order to the improve cell response. A novel nanocomposite structure in the form of 15x(Ti/Zr)/Si multilayer thin films, with satisfying mechanical properties and moderate biocompatibility, was deposited by ion sputtering on an Si substrate. The multilayer 15×(Ti/Zr)/Si thin films were modified by femtosecond laser pulses in air to induce the following modifications: (i) mixing of components inside of the multilayer structures, (ii) the formation of an ultrathin oxide layer at the surfaces, and (iii) surface nano-texturing with the creation of laser-induced periodic surface structure (LIPSS). The focus of this study was an examination of the novel Ti/Zr multilayer thin films in order to create a surface texture with suitable composition and structure for cell integration. Using the SEM and confocal microscopies of the laser-modified Ti/Zr surfaces with seeded cell culture (NIH 3T3 fibroblasts), it was found that cell adhesion and growth depend on the surface composition and morphological patterns. These results indicated a good proliferation of cells after two and four days with some tendency of the cell orientation along the LIPSSs. © 2020 by the authors. Licensee MDPI, Basel, Switzerland.
T2  - Nanomaterials
T1  - Response of NIH 3T3 fibroblast cells on laser-induced periodic surface structures on a 15×(Ti/Zr)/Si multilayer system
VL  - 10
IS  - 12
SP  - 1
EP  - 14
DO  - 10.3390/nano10122531
ER  - 

@article{
author = "Petrović, Suzana and Peruško, Davor and Mimidis, Alexandros and Kavatzikidou, Paraskevi and Kovač, Janez and Ranella, Anthi and Novaković, Mirjana M. and Popović, Maja and Stratakis, Emmanuel",
year = "2020",
abstract = "Ultrafast laser processing with the formation of periodic surface nanostructures on the 15×(Ti/Zr)/Si multilayers is studied in order to the improve cell response. A novel nanocomposite structure in the form of 15x(Ti/Zr)/Si multilayer thin films, with satisfying mechanical properties and moderate biocompatibility, was deposited by ion sputtering on an Si substrate. The multilayer 15×(Ti/Zr)/Si thin films were modified by femtosecond laser pulses in air to induce the following modifications: (i) mixing of components inside of the multilayer structures, (ii) the formation of an ultrathin oxide layer at the surfaces, and (iii) surface nano-texturing with the creation of laser-induced periodic surface structure (LIPSS). The focus of this study was an examination of the novel Ti/Zr multilayer thin films in order to create a surface texture with suitable composition and structure for cell integration. Using the SEM and confocal microscopies of the laser-modified Ti/Zr surfaces with seeded cell culture (NIH 3T3 fibroblasts), it was found that cell adhesion and growth depend on the surface composition and morphological patterns. These results indicated a good proliferation of cells after two and four days with some tendency of the cell orientation along the LIPSSs. © 2020 by the authors. Licensee MDPI, Basel, Switzerland.",
journal = "Nanomaterials",
title = "Response of NIH 3T3 fibroblast cells on laser-induced periodic surface structures on a 15×(Ti/Zr)/Si multilayer system",
volume = "10",
number = "12",
pages = "1-14",
doi = "10.3390/nano10122531"
}

Petrović, S., Peruško, D., Mimidis, A., Kavatzikidou, P., Kovač, J., Ranella, A., Novaković, M. M., Popović, M.,& Stratakis, E.. (2020). Response of NIH 3T3 fibroblast cells on laser-induced periodic surface structures on a 15×(Ti/Zr)/Si multilayer system. in Nanomaterials, 10(12), 1-14.
https://doi.org/10.3390/nano10122531

Petrović S, Peruško D, Mimidis A, Kavatzikidou P, Kovač J, Ranella A, Novaković MM, Popović M, Stratakis E. Response of NIH 3T3 fibroblast cells on laser-induced periodic surface structures on a 15×(Ti/Zr)/Si multilayer system. in Nanomaterials. 2020;10(12):1-14.
doi:10.3390/nano10122531 .

Petrović, Suzana, Peruško, Davor, Mimidis, Alexandros, Kavatzikidou, Paraskevi, Kovač, Janez, Ranella, Anthi, Novaković, Mirjana M., Popović, Maja, Stratakis, Emmanuel, "Response of NIH 3T3 fibroblast cells on laser-induced periodic surface structures on a 15×(Ti/Zr)/Si multilayer system" in Nanomaterials, 10, no. 12 (2020):1-14,
https://doi.org/10.3390/nano10122531 . .