@conference{
author = "Čolović, Mirjana B. and Vasić, Vesna M. and Avramović, Nataša and Đurić, Dragan M. and Krstić, Danijela Z.",
year = "2014",
abstract = "In vitro evaluation of oxidative stress responses to various concentrations of diazinon and its degradation products, diazoxon and 2-isopropyl-6-methyl- 4-pyrimidinol (IMP) was investigated by determining antioxidant enzymes activity (catalase (CAT), superoxide dismutase (SOD) and glutathione peroxidase (GPx)) and lipid peroxidation level in rat brain synaptosomes. Diazinon showed negligible prooxidative properties causing increase in antioxidant enzymes activity and lipid peroxidation level up to 10%. Increasing concentrations of diazinon oxidation product, diazoxon activated CAT (up to 20%), SOD (up to 50%), GPx (up to 25%), and significantly increased the content of lipid peroxidation indicator (up to 50%). The investigated hydrolysis product of diazinon, IMP did not remarkably influence the activity of CAT, GPx and lipid peroxidation level (up to 10%), while it induced SOD stimulation up to 30%.",
publisher = "Society of Physical Chemists of Serbia",
journal = "Physical chemistry 2014: 12th International Conference on Fundamental and Applied Aspects of Physical Chemistry",
title = "The effects of diazinon and its degradation products on oxidative stress parameters in rat brain synaptosomes",
volume = "F-24-P",
url = "https://hdl.handle.net/21.15107/rcub_vinar_9195"
}