@conference{
author = "Nešković, Olivera M. and Rakočević, Zlatko and Bibić, Nataša and Cvetićanin, Jelena and Trpkov, Đorđe and Rogić, Zorana and Vlatković, Danka",
year = "2011",
abstract = "Bone is composed of two phases. The organic phase is made of collagen fibrils assembled in broad fibers acting as a template for mineralization. The mineral phase comprises hydroxyapatite (HAP) crystals grown between and inside the collagen fibers. We have developed a material using functionalized carbon nanotubes, carbon fibers and glasy carbon as scaffold to initiate in vitro mineralization. Mentioned carbon materials are functionalized with carboxylic groups prior to decorating. All samples were dispersed in ultra-pure water and incubated for 2 weeks in a synthetic body fluid with dispersed HAP, in order to induce the calcification of the functionalized carbon materials. Atomic force microscopy (AFM) and transmision electron microscopy (TEM) showed that Ca2+ and PO4 3- ions were deposited as round-shaped nodules. Raman spectroscopic studies confirmed the HAP formation, and image analysis made on TEM pictures showed that HAP were packed around and inside the carbon materials together. All three types of investigated carbon materials leading to successful calcification of collagen. This suggests that it takes the presence of carbon materials to prevent it from calcification of collagen, independent of the structures of the material.",
publisher = "Belgrade : Institute for Multidisciplinary Research, University of Belgrade",
journal = "1CSCS-2011 : 1st Conference of the Serbian Ceramic Materials : program and the book of abstracts; March 17-18, Belgrade",
title = "The calcification of collagen by HAP functionalized carbon materials",
pages = "50-50",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12402"
}