TY  - JOUR
AU  - Lukić, Dragoljub M.
AU  - Tamburella, Claire
AU  - Buchegger, Franz
AU  - Beyer, Gerd-Juergen
AU  - Čomor, Jožef J.
AU  - Seimbille, Yann
PY  - 2009
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3655
AB  - As an intermediate half-life positron emitter (86)Y is an attractive radioisotope for positron emission tomography (PET) studies, particularly for patient specific dosimetry planning of (90)Y-based radiotherapy procedures. It can be conveniently produced by a small-sized cyclotron via the (86)Sr(p,n)(86)Y nuclear reaction. The optimization of the electrochemical separation of (86)Y from the target material and its purification was done by modeling the whole production cycle using (90)Y. The radionuclide was isolated using four electrodes in two electrolytic steps. In the first step two Pt plate anodes and a Pt Winkler cathode were used and the electro-deposition yield was determined in constant current mode of operation. In addition, the influence of pH on the efficiency of this first step was investigated. The second electrolysis, with Winkler electrode as anode and a Pt wire as cathode, was also performed in constant current mode of operation. The kinetics of recovery of the deposited activity on the Pt wire was investigated in acidic solutions. The optimized electrochemical method was then applied for (86)Y separation and purification. This modified procedure was proved to be faster and simpler than the previously proposed electrochemical techniques and is more convenient for automation of the routine production of (86)Y. (C) 2008 Elsevier Ltd. All rights reserved.
T2  - Applied Radiation and Isotopes
T1  - High efficiency production and purification of (86)Y based on electrochemical separation
VL  - 67
IS  - 4
SP  - 523
EP  - 529
DO  - 10.1016/j.apradiso.2008.12.008
ER  - 

@article{
author = "Lukić, Dragoljub M. and Tamburella, Claire and Buchegger, Franz and Beyer, Gerd-Juergen and Čomor, Jožef J. and Seimbille, Yann",
year = "2009",
abstract = "As an intermediate half-life positron emitter (86)Y is an attractive radioisotope for positron emission tomography (PET) studies, particularly for patient specific dosimetry planning of (90)Y-based radiotherapy procedures. It can be conveniently produced by a small-sized cyclotron via the (86)Sr(p,n)(86)Y nuclear reaction. The optimization of the electrochemical separation of (86)Y from the target material and its purification was done by modeling the whole production cycle using (90)Y. The radionuclide was isolated using four electrodes in two electrolytic steps. In the first step two Pt plate anodes and a Pt Winkler cathode were used and the electro-deposition yield was determined in constant current mode of operation. In addition, the influence of pH on the efficiency of this first step was investigated. The second electrolysis, with Winkler electrode as anode and a Pt wire as cathode, was also performed in constant current mode of operation. The kinetics of recovery of the deposited activity on the Pt wire was investigated in acidic solutions. The optimized electrochemical method was then applied for (86)Y separation and purification. This modified procedure was proved to be faster and simpler than the previously proposed electrochemical techniques and is more convenient for automation of the routine production of (86)Y. (C) 2008 Elsevier Ltd. All rights reserved.",
journal = "Applied Radiation and Isotopes",
title = "High efficiency production and purification of (86)Y based on electrochemical separation",
volume = "67",
number = "4",
pages = "523-529",
doi = "10.1016/j.apradiso.2008.12.008"
}

Lukić, D. M., Tamburella, C., Buchegger, F., Beyer, G., Čomor, J. J.,& Seimbille, Y.. (2009). High efficiency production and purification of (86)Y based on electrochemical separation. in Applied Radiation and Isotopes, 67(4), 523-529.
https://doi.org/10.1016/j.apradiso.2008.12.008

Lukić DM, Tamburella C, Buchegger F, Beyer G, Čomor JJ, Seimbille Y. High efficiency production and purification of (86)Y based on electrochemical separation. in Applied Radiation and Isotopes. 2009;67(4):523-529.
doi:10.1016/j.apradiso.2008.12.008 .

Lukić, Dragoljub M., Tamburella, Claire, Buchegger, Franz, Beyer, Gerd-Juergen, Čomor, Jožef J., Seimbille, Yann, "High efficiency production and purification of (86)Y based on electrochemical separation" in Applied Radiation and Isotopes, 67, no. 4 (2009):523-529,
https://doi.org/10.1016/j.apradiso.2008.12.008 . .

TY  - CONF
AU  - Lukić, Dragoljub
AU  - Tamburella, C.
AU  - Buchegger, F.
AU  - Beyer, G. J.
AU  - Čomor, Jožef J.
AU  - Seimbille, Y.
PY  - 2009
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3764
C3  - Journal of Labelled Compounds and Radiopharmaceuticals
T1  - Production of Carrier-Free 86y for Nuclear Medical Application Using Enriched 86sro
VL  - 52
SP  - S243
EP  - S243
UR  - https://hdl.handle.net/21.15107/rcub_vinar_3764
ER  - 

@conference{
author = "Lukić, Dragoljub and Tamburella, C. and Buchegger, F. and Beyer, G. J. and Čomor, Jožef J. and Seimbille, Y.",
year = "2009",
journal = "Journal of Labelled Compounds and Radiopharmaceuticals",
title = "Production of Carrier-Free 86y for Nuclear Medical Application Using Enriched 86sro",
volume = "52",
pages = "S243-S243",
url = "https://hdl.handle.net/21.15107/rcub_vinar_3764"
}

Lukić, D., Tamburella, C., Buchegger, F., Beyer, G. J., Čomor, J. J.,& Seimbille, Y.. (2009). Production of Carrier-Free 86y for Nuclear Medical Application Using Enriched 86sro. in Journal of Labelled Compounds and Radiopharmaceuticals, 52, S243-S243.
https://hdl.handle.net/21.15107/rcub_vinar_3764

Lukić D, Tamburella C, Buchegger F, Beyer GJ, Čomor JJ, Seimbille Y. Production of Carrier-Free 86y for Nuclear Medical Application Using Enriched 86sro. in Journal of Labelled Compounds and Radiopharmaceuticals. 2009;52:S243-S243.
https://hdl.handle.net/21.15107/rcub_vinar_3764 .

Lukić, Dragoljub, Tamburella, C., Buchegger, F., Beyer, G. J., Čomor, Jožef J., Seimbille, Y., "Production of Carrier-Free 86y for Nuclear Medical Application Using Enriched 86sro" in Journal of Labelled Compounds and Radiopharmaceuticals, 52 (2009):S243-S243,
https://hdl.handle.net/21.15107/rcub_vinar_3764 .

TY  - JOUR
AU  - Dobrosavljević, Aleksandar S.
AU  - Nešković, Nebojša B.
AU  - Beličev, Petar
AU  - Čomor, Jožef J.
AU  - Vujović, Velibor V.
AU  - Balvanović, Roman V.
AU  - Ristić-Đurović, Jasna L.
PY  - 2008
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3600
AB  - t present, heavy ion beams from the electron cyclotron resonance (ECR) ion source in the Laboratory of Physics of the Vinca Institute of Nuclear Sciences, Belgrade, Serbia, are employed in a channel for surface modification of materials. The source and channel were commissioned in 1998, and have been used since that time by a number of user groups from the Vinca Institute and other scientific and educational institutions in Serbia. However, since the maximum extraction voltage of the source is +25 kV, sometimes the extracted beams do not have sufficiently high energies for such applications. Therefore, in order to solve this problem, we have decided to construct a new channel, to be used for deeper modification of materials. The beams obtained from the source will be post-accelerated by biasing the target to be irradiated to the negative potentials of down to - 100 W For example, we shall be able to bombard the target with the (132)Xe(24+) beam of the energy of up to 3 MeV, instead of up to 600 keV, in the case without the biasing system. An additional possibility will be to bias the target to the positive potentials of up to +25 kV and thus decelerate the beams extracted from the source down to the energies of about 1 keV. Consequently, one will be able to modify materials with the beams in a wide energy range, from similar to 1 to similar to 3 MeV, which is rarely met at similar experimental set-ups. It must be noted that changing the post-accelerated or decelerated beam energy in the new channel will be performed simply by adjusting the power supply of the biasing system, without any adjustments of the source and of the transport elements between the source and the interaction chamber. (C) 2008 Elsevier B.V. All rights reserved.
T2  - Nuclear Instruments and Methods in Physics Research. Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment
T1  - A channel for modification of materials with post-accelerated or decelerated multiply charged ion beams
VL  - 597
IS  - 2-3
SP  - 136
EP  - 141
DO  - 10.1016/j.nima.2008.08.148
ER  - 

@article{
author = "Dobrosavljević, Aleksandar S. and Nešković, Nebojša B. and Beličev, Petar and Čomor, Jožef J. and Vujović, Velibor V. and Balvanović, Roman V. and Ristić-Đurović, Jasna L.",
year = "2008",
abstract = "t present, heavy ion beams from the electron cyclotron resonance (ECR) ion source in the Laboratory of Physics of the Vinca Institute of Nuclear Sciences, Belgrade, Serbia, are employed in a channel for surface modification of materials. The source and channel were commissioned in 1998, and have been used since that time by a number of user groups from the Vinca Institute and other scientific and educational institutions in Serbia. However, since the maximum extraction voltage of the source is +25 kV, sometimes the extracted beams do not have sufficiently high energies for such applications. Therefore, in order to solve this problem, we have decided to construct a new channel, to be used for deeper modification of materials. The beams obtained from the source will be post-accelerated by biasing the target to be irradiated to the negative potentials of down to - 100 W For example, we shall be able to bombard the target with the (132)Xe(24+) beam of the energy of up to 3 MeV, instead of up to 600 keV, in the case without the biasing system. An additional possibility will be to bias the target to the positive potentials of up to +25 kV and thus decelerate the beams extracted from the source down to the energies of about 1 keV. Consequently, one will be able to modify materials with the beams in a wide energy range, from similar to 1 to similar to 3 MeV, which is rarely met at similar experimental set-ups. It must be noted that changing the post-accelerated or decelerated beam energy in the new channel will be performed simply by adjusting the power supply of the biasing system, without any adjustments of the source and of the transport elements between the source and the interaction chamber. (C) 2008 Elsevier B.V. All rights reserved.",
journal = "Nuclear Instruments and Methods in Physics Research. Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment",
title = "A channel for modification of materials with post-accelerated or decelerated multiply charged ion beams",
volume = "597",
number = "2-3",
pages = "136-141",
doi = "10.1016/j.nima.2008.08.148"
}

Dobrosavljević, A. S., Nešković, N. B., Beličev, P., Čomor, J. J., Vujović, V. V., Balvanović, R. V.,& Ristić-Đurović, J. L.. (2008). A channel for modification of materials with post-accelerated or decelerated multiply charged ion beams. in Nuclear Instruments and Methods in Physics Research. Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment, 597(2-3), 136-141.
https://doi.org/10.1016/j.nima.2008.08.148

Dobrosavljević AS, Nešković NB, Beličev P, Čomor JJ, Vujović VV, Balvanović RV, Ristić-Đurović JL. A channel for modification of materials with post-accelerated or decelerated multiply charged ion beams. in Nuclear Instruments and Methods in Physics Research. Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment. 2008;597(2-3):136-141.
doi:10.1016/j.nima.2008.08.148 .

Dobrosavljević, Aleksandar S., Nešković, Nebojša B., Beličev, Petar, Čomor, Jožef J., Vujović, Velibor V., Balvanović, Roman V., Ristić-Đurović, Jasna L., "A channel for modification of materials with post-accelerated or decelerated multiply charged ion beams" in Nuclear Instruments and Methods in Physics Research. Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment, 597, no. 2-3 (2008):136-141,
https://doi.org/10.1016/j.nima.2008.08.148 . .

TY  - JOUR
AU  - Kumrić, Ksenija
AU  - Trtić-Petrović, Tatjana M.
AU  - Ignjatović, Ljubiša M.
AU  - Čomor, Jožef J.
PY  - 2008
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3348
AB  - Lutetium has been determined by differential pulse anodic stripping voltammetry in an acidic solution containing Zn-EDTA. Lutetium (III) ions liberated zinc (II), which was preconcentrated on a hanging mercury drop electrode and stripped anodically, resulting in peak current linearly dependent on lutetium (III) concentration. Less than 0.4 ng mL(-1) lutetium could be detected after a 2 min deposition.
T2  - Central European Journal of Chemistry
T1  - Indirect determination of lutetium by differential pulse anodic stripping voltammetry at a hanging mercury drop electrode
VL  - 6
IS  - 1
SP  - 65
EP  - 69
DO  - 10.2478/s11532-007-0055-3
ER  - 

@article{
author = "Kumrić, Ksenija and Trtić-Petrović, Tatjana M. and Ignjatović, Ljubiša M. and Čomor, Jožef J.",
year = "2008",
abstract = "Lutetium has been determined by differential pulse anodic stripping voltammetry in an acidic solution containing Zn-EDTA. Lutetium (III) ions liberated zinc (II), which was preconcentrated on a hanging mercury drop electrode and stripped anodically, resulting in peak current linearly dependent on lutetium (III) concentration. Less than 0.4 ng mL(-1) lutetium could be detected after a 2 min deposition.",
journal = "Central European Journal of Chemistry",
title = "Indirect determination of lutetium by differential pulse anodic stripping voltammetry at a hanging mercury drop electrode",
volume = "6",
number = "1",
pages = "65-69",
doi = "10.2478/s11532-007-0055-3"
}

Kumrić, K., Trtić-Petrović, T. M., Ignjatović, L. M.,& Čomor, J. J.. (2008). Indirect determination of lutetium by differential pulse anodic stripping voltammetry at a hanging mercury drop electrode. in Central European Journal of Chemistry, 6(1), 65-69.
https://doi.org/10.2478/s11532-007-0055-3

Kumrić K, Trtić-Petrović TM, Ignjatović LM, Čomor JJ. Indirect determination of lutetium by differential pulse anodic stripping voltammetry at a hanging mercury drop electrode. in Central European Journal of Chemistry. 2008;6(1):65-69.
doi:10.2478/s11532-007-0055-3 .

Kumrić, Ksenija, Trtić-Petrović, Tatjana M., Ignjatović, Ljubiša M., Čomor, Jožef J., "Indirect determination of lutetium by differential pulse anodic stripping voltammetry at a hanging mercury drop electrode" in Central European Journal of Chemistry, 6, no. 1 (2008):65-69,
https://doi.org/10.2478/s11532-007-0055-3 . .

TY  - CONF
AU  - Kumrić, Ksenija
AU  - Trtić-Petrović, Tatjana M.
AU  - Čomor, Jožef J.
PY  - 2008
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9361
AB  - Simultaneous determination of copper(II) and nickel(II) by ion chromatography (IC) has been optimized and the detection limits of the new method were compared to stripping voltammetry. The best eluent enabling fast end efficient separation of Cu(II) and Ni(II) is a mixture of 8 mM citric and 0.3 mM oxalic acid using a Metrosep C2 (Metrohm) IC column. The detection limits are significantly lower using stripping voltammetry, while IC is considerably faster.
PB  - Society of Physical Chemists of Serbia
C3  - Physical chemistry 2008 : 9th international conference on fundamental and applied aspects of physical chemistry
T1  - Determination of copper and nickel by ion chromatography and voltammetry
VL  - 1
SP  - 265
EP  - 267
UR  - https://hdl.handle.net/21.15107/rcub_vinar_9361
ER  - 

@conference{
author = "Kumrić, Ksenija and Trtić-Petrović, Tatjana M. and Čomor, Jožef J.",
year = "2008",
abstract = "Simultaneous determination of copper(II) and nickel(II) by ion chromatography (IC) has been optimized and the detection limits of the new method were compared to stripping voltammetry. The best eluent enabling fast end efficient separation of Cu(II) and Ni(II) is a mixture of 8 mM citric and 0.3 mM oxalic acid using a Metrosep C2 (Metrohm) IC column. The detection limits are significantly lower using stripping voltammetry, while IC is considerably faster.",
publisher = "Society of Physical Chemists of Serbia",
journal = "Physical chemistry 2008 : 9th international conference on fundamental and applied aspects of physical chemistry",
title = "Determination of copper and nickel by ion chromatography and voltammetry",
volume = "1",
pages = "265-267",
url = "https://hdl.handle.net/21.15107/rcub_vinar_9361"
}

Kumrić, K., Trtić-Petrović, T. M.,& Čomor, J. J.. (2008). Determination of copper and nickel by ion chromatography and voltammetry. in Physical chemistry 2008 : 9th international conference on fundamental and applied aspects of physical chemistry
Society of Physical Chemists of Serbia., 1, 265-267.
https://hdl.handle.net/21.15107/rcub_vinar_9361

Kumrić K, Trtić-Petrović TM, Čomor JJ. Determination of copper and nickel by ion chromatography and voltammetry. in Physical chemistry 2008 : 9th international conference on fundamental and applied aspects of physical chemistry. 2008;1:265-267.
https://hdl.handle.net/21.15107/rcub_vinar_9361 .

Kumrić, Ksenija, Trtić-Petrović, Tatjana M., Čomor, Jožef J., "Determination of copper and nickel by ion chromatography and voltammetry" in Physical chemistry 2008 : 9th international conference on fundamental and applied aspects of physical chemistry, 1 (2008):265-267,
https://hdl.handle.net/21.15107/rcub_vinar_9361 .

TY  - CONF
AU  - Trtić-Petrović, Tatjana M.
AU  - Kumrić, Ksenija
AU  - Koumarianou, Eftichia
AU  - Archimandritis, Spyridon
AU  - Čomor, Jožef J.
PY  - 2006
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2716
C3  - European Journal of Nuclear Medicine and Molecular Imaging
T1  - Membrane extraction - a new method for purification of labeled compounds
VL  - 33
SP  - S308
EP  - S308
UR  - https://hdl.handle.net/21.15107/rcub_vinar_2716
ER  - 

@conference{
author = "Trtić-Petrović, Tatjana M. and Kumrić, Ksenija and Koumarianou, Eftichia and Archimandritis, Spyridon and Čomor, Jožef J.",
year = "2006",
journal = "European Journal of Nuclear Medicine and Molecular Imaging",
title = "Membrane extraction - a new method for purification of labeled compounds",
volume = "33",
pages = "S308-S308",
url = "https://hdl.handle.net/21.15107/rcub_vinar_2716"
}

Trtić-Petrović, T. M., Kumrić, K., Koumarianou, E., Archimandritis, S.,& Čomor, J. J.. (2006). Membrane extraction - a new method for purification of labeled compounds. in European Journal of Nuclear Medicine and Molecular Imaging, 33, S308-S308.
https://hdl.handle.net/21.15107/rcub_vinar_2716

Trtić-Petrović TM, Kumrić K, Koumarianou E, Archimandritis S, Čomor JJ. Membrane extraction - a new method for purification of labeled compounds. in European Journal of Nuclear Medicine and Molecular Imaging. 2006;33:S308-S308.
https://hdl.handle.net/21.15107/rcub_vinar_2716 .

Trtić-Petrović, Tatjana M., Kumrić, Ksenija, Koumarianou, Eftichia, Archimandritis, Spyridon, Čomor, Jožef J., "Membrane extraction - a new method for purification of labeled compounds" in European Journal of Nuclear Medicine and Molecular Imaging, 33 (2006):S308-S308,
https://hdl.handle.net/21.15107/rcub_vinar_2716 .

TY  - JOUR
AU  - Kumrić, Ksenija
AU  - Trtić-Petrović, Tatjana M.
AU  - Koumarianou, Eftichia
AU  - Archimandritis, Spyridon
AU  - Čomor, Jožef J.
PY  - 2006
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3111
AB  - Permeation of Lu-177(III) through supported hexane membrane containing di-(2-ethythexyl)phosphoric acid (DEHPA) as a carrier has been studied. The donor solution was 0.2 mol dm(-3) ammonium acetate buffer, pH 5.0-5.5, that is optimal for peptide labeling, and the acceptor solution was 2 mol dm(-3) HCl. A miniaturized supported liquid membrane (SLM) contactor with 10 mu l donor and acceptor channel and ultra thin, flat poly(tetrafluoroethene) laminated on polyester fleece (PTFE) was applied in the work reported herein. The donor phase was pumped continuously through the donor channel, while the acceptor was stagnant during the SLM extraction. The influences of carrier concentration and donor flow rate on extraction of Lu-177(III) have been investigated. The results are discussed in the term of mass transfer coefficient, mass transfer resistance and extraction efficiency. Based on the experimental results of SLM extraction of Lu-177(III), this technique has been applied for the separation of free radionuclide from the labeled peptide as a purification procedure within the production of the radiopharmaceutical. An analog of somatostatin, lanreotide, which was conjugated with chelating moiety 1,4,7,10-tetraazacyclododecane-N,N,N,N-tetraacetic acid (DOTA) was labeled with Lu-177(III). The characterization of the labeled conjugate as well as the complexation yield and the efficiency of purification by membrane extraction were carried out by HPLC analysis. (c) 2006 Elsevier B.V. All rights reserved.
T2  - Separation and Purification Technology
T1  - Supported liquid membrane extraction of Lu-177(III) with DEHPA and its application for purification of Lu-177-DOTA-lanreotide
VL  - 51
IS  - 3
SP  - 310
EP  - 317
DO  - 10.1016/j.seppur.2006.02.011
ER  - 

@article{
author = "Kumrić, Ksenija and Trtić-Petrović, Tatjana M. and Koumarianou, Eftichia and Archimandritis, Spyridon and Čomor, Jožef J.",
year = "2006",
abstract = "Permeation of Lu-177(III) through supported hexane membrane containing di-(2-ethythexyl)phosphoric acid (DEHPA) as a carrier has been studied. The donor solution was 0.2 mol dm(-3) ammonium acetate buffer, pH 5.0-5.5, that is optimal for peptide labeling, and the acceptor solution was 2 mol dm(-3) HCl. A miniaturized supported liquid membrane (SLM) contactor with 10 mu l donor and acceptor channel and ultra thin, flat poly(tetrafluoroethene) laminated on polyester fleece (PTFE) was applied in the work reported herein. The donor phase was pumped continuously through the donor channel, while the acceptor was stagnant during the SLM extraction. The influences of carrier concentration and donor flow rate on extraction of Lu-177(III) have been investigated. The results are discussed in the term of mass transfer coefficient, mass transfer resistance and extraction efficiency. Based on the experimental results of SLM extraction of Lu-177(III), this technique has been applied for the separation of free radionuclide from the labeled peptide as a purification procedure within the production of the radiopharmaceutical. An analog of somatostatin, lanreotide, which was conjugated with chelating moiety 1,4,7,10-tetraazacyclododecane-N,N,N,N-tetraacetic acid (DOTA) was labeled with Lu-177(III). The characterization of the labeled conjugate as well as the complexation yield and the efficiency of purification by membrane extraction were carried out by HPLC analysis. (c) 2006 Elsevier B.V. All rights reserved.",
journal = "Separation and Purification Technology",
title = "Supported liquid membrane extraction of Lu-177(III) with DEHPA and its application for purification of Lu-177-DOTA-lanreotide",
volume = "51",
number = "3",
pages = "310-317",
doi = "10.1016/j.seppur.2006.02.011"
}

Kumrić, K., Trtić-Petrović, T. M., Koumarianou, E., Archimandritis, S.,& Čomor, J. J.. (2006). Supported liquid membrane extraction of Lu-177(III) with DEHPA and its application for purification of Lu-177-DOTA-lanreotide. in Separation and Purification Technology, 51(3), 310-317.
https://doi.org/10.1016/j.seppur.2006.02.011

Kumrić K, Trtić-Petrović TM, Koumarianou E, Archimandritis S, Čomor JJ. Supported liquid membrane extraction of Lu-177(III) with DEHPA and its application for purification of Lu-177-DOTA-lanreotide. in Separation and Purification Technology. 2006;51(3):310-317.
doi:10.1016/j.seppur.2006.02.011 .

Kumrić, Ksenija, Trtić-Petrović, Tatjana M., Koumarianou, Eftichia, Archimandritis, Spyridon, Čomor, Jožef J., "Supported liquid membrane extraction of Lu-177(III) with DEHPA and its application for purification of Lu-177-DOTA-lanreotide" in Separation and Purification Technology, 51, no. 3 (2006):310-317,
https://doi.org/10.1016/j.seppur.2006.02.011 . .

TY  - CONF
AU  - Kumrić, Ksenija
AU  - Trtić-Petrović, Tatjana M.
AU  - Čomor, Jožef J.
PY  - 2006
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9418
AB  - Half wave potential of lutetium was determined by anodic stripping voltammetry using various electrolyte solutions at the mercury electrode. The influence of electrolyte pH on the value of peak current was also observed. The results show that the choice of the supporting electrolyte and the electrolyte pH strongly influence the voltammetric behaviour of lutetium.
PB  - Society of Physical Chemists of Serbia
C3  - Physical chemistry 2006: 8th international conference on fundemental and applied aspract of physical chemistry
T1  - Voltammetric determination of lutetium
SP  - 326
EP  - 328
UR  - https://hdl.handle.net/21.15107/rcub_vinar_9418
ER  - 

@conference{
author = "Kumrić, Ksenija and Trtić-Petrović, Tatjana M. and Čomor, Jožef J.",
year = "2006",
abstract = "Half wave potential of lutetium was determined by anodic stripping voltammetry using various electrolyte solutions at the mercury electrode. The influence of electrolyte pH on the value of peak current was also observed. The results show that the choice of the supporting electrolyte and the electrolyte pH strongly influence the voltammetric behaviour of lutetium.",
publisher = "Society of Physical Chemists of Serbia",
journal = "Physical chemistry 2006: 8th international conference on fundemental and applied aspract of physical chemistry",
title = "Voltammetric determination of lutetium",
pages = "326-328",
url = "https://hdl.handle.net/21.15107/rcub_vinar_9418"
}

Kumrić, K., Trtić-Petrović, T. M.,& Čomor, J. J.. (2006). Voltammetric determination of lutetium. in Physical chemistry 2006: 8th international conference on fundemental and applied aspract of physical chemistry
Society of Physical Chemists of Serbia., 326-328.
https://hdl.handle.net/21.15107/rcub_vinar_9418

Kumrić K, Trtić-Petrović TM, Čomor JJ. Voltammetric determination of lutetium. in Physical chemistry 2006: 8th international conference on fundemental and applied aspract of physical chemistry. 2006;:326-328.
https://hdl.handle.net/21.15107/rcub_vinar_9418 .

Kumrić, Ksenija, Trtić-Petrović, Tatjana M., Čomor, Jožef J., "Voltammetric determination of lutetium" in Physical chemistry 2006: 8th international conference on fundemental and applied aspract of physical chemistry (2006):326-328,
https://hdl.handle.net/21.15107/rcub_vinar_9418 .

TY  - CONF
AU  - Abazović, Nadica
AU  - Čomor, Jožef J.
AU  - Čomor, Mirjana
PY  - 2004
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9503
AB  - Chlorpyrifos dissolved in methanol was illuminated by the Xe polychromatic light source, which is commonly used as artificial solar radiation source. Photolytic degradation of the parent compound was followed by UV/Vis spectrophotometry and GC/MS technique. GC/MS measurementsindicated that very few pyridine containing intermediates are formed during the degradation process. After 2 hours of illumination almost no chlorpyrifos could be observed and significant mineralization (formation of carbon dioxide, water, alkyl phosphates and sulfates) was achieved.
PB  - Society of Physical Chemists of Serbia
C3  - Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry
T1  - Photolytic degradation of chlorpyrifos induced by an artificial light source
VL  - 1
SP  - 407
EP  - 409
UR  - https://hdl.handle.net/21.15107/rcub_vinar_9503
ER  - 

@conference{
author = "Abazović, Nadica and Čomor, Jožef J. and Čomor, Mirjana",
year = "2004",
abstract = "Chlorpyrifos dissolved in methanol was illuminated by the Xe polychromatic light source, which is commonly used as artificial solar radiation source. Photolytic degradation of the parent compound was followed by UV/Vis spectrophotometry and GC/MS technique. GC/MS measurementsindicated that very few pyridine containing intermediates are formed during the degradation process. After 2 hours of illumination almost no chlorpyrifos could be observed and significant mineralization (formation of carbon dioxide, water, alkyl phosphates and sulfates) was achieved.",
publisher = "Society of Physical Chemists of Serbia",
journal = "Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry",
title = "Photolytic degradation of chlorpyrifos induced by an artificial light source",
volume = "1",
pages = "407-409",
url = "https://hdl.handle.net/21.15107/rcub_vinar_9503"
}

Abazović, N., Čomor, J. J.,& Čomor, M.. (2004). Photolytic degradation of chlorpyrifos induced by an artificial light source. in Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry
Society of Physical Chemists of Serbia., 1, 407-409.
https://hdl.handle.net/21.15107/rcub_vinar_9503

Abazović N, Čomor JJ, Čomor M. Photolytic degradation of chlorpyrifos induced by an artificial light source. in Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry. 2004;1:407-409.
https://hdl.handle.net/21.15107/rcub_vinar_9503 .

Abazović, Nadica, Čomor, Jožef J., Čomor, Mirjana, "Photolytic degradation of chlorpyrifos induced by an artificial light source" in Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry, 1 (2004):407-409,
https://hdl.handle.net/21.15107/rcub_vinar_9503 .

TY  - JOUR
AU  - Čomor, Jožef J.
AU  - Stevanović, Žarko M.
AU  - Rajcevic, M
AU  - Košutić, Duško D.
PY  - 2004
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/6415
AB  - Three radionuclides of iodine (I-121, I-123 and I-124) are of great interest for modern nuclear medical diagnostics. They can be all produced by the (p,n) nuclear reaction using isotopically enriched solid TeO2, targets. The produced radioiodine can be rapidly separated from the target material by dry-distillation from the melted target after the irradiation. Since TeO2 has low thermal conductivity, the most critical issue in the design of a production target is the provision of its effective cooling in order to avoid melting of the oxide layer during the irradiation. A compact solid target irradiation system (COSTIS) has been designed for the irradiation of TeO2 targets, suitable for routine production of radioiodine. The target is a circular Pt-disk that carries the TeO2 melted into a circular grove in the center of the disk. The target coin is manually inserted into COSTIS, fixed pneumatically in the irradiation position, released remotely after irradiation and falls down driven by gravity into a transport container. The engineering design of the cavity for helium cooling of the front face of TeO2 and the impinging water jet cooling the back face of the target disk was done based on a simulation of the thermal behavior of the target during the irradiation. A straightforward numerical method for the prediction of the thermal properties of the solid target has been developed. The approach is based on calculations without using the common practice of Prandtl and Nusselt empirical correlation. The fluid flow description in the boundary layer was refined in such a way, that the heat flux, exchanged between the solid and fluid, is obtained directly from Fourier law. The governing equations are based on the local thermodynamic equilibrium and conservation equation of mass, momentum and energy. In order to solve the set of governing equations, the finite-volume method is used. This procedure gives rapid answers whether the proposed geometry satisfies the design criteria. (C) 2003 Elsevier B.V. All rights reserved.
T2  - Nuclear Instruments and Methods in Physics Research. Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment
T1  - Modeling of thermal properties of a TeO2 target for radioiodine production
VL  - 521
IS  - 1
SP  - 161
EP  - 170
DO  - 10.1016/j.nima.2003.11.147
ER  - 

@article{
author = "Čomor, Jožef J. and Stevanović, Žarko M. and Rajcevic, M and Košutić, Duško D.",
year = "2004",
abstract = "Three radionuclides of iodine (I-121, I-123 and I-124) are of great interest for modern nuclear medical diagnostics. They can be all produced by the (p,n) nuclear reaction using isotopically enriched solid TeO2, targets. The produced radioiodine can be rapidly separated from the target material by dry-distillation from the melted target after the irradiation. Since TeO2 has low thermal conductivity, the most critical issue in the design of a production target is the provision of its effective cooling in order to avoid melting of the oxide layer during the irradiation. A compact solid target irradiation system (COSTIS) has been designed for the irradiation of TeO2 targets, suitable for routine production of radioiodine. The target is a circular Pt-disk that carries the TeO2 melted into a circular grove in the center of the disk. The target coin is manually inserted into COSTIS, fixed pneumatically in the irradiation position, released remotely after irradiation and falls down driven by gravity into a transport container. The engineering design of the cavity for helium cooling of the front face of TeO2 and the impinging water jet cooling the back face of the target disk was done based on a simulation of the thermal behavior of the target during the irradiation. A straightforward numerical method for the prediction of the thermal properties of the solid target has been developed. The approach is based on calculations without using the common practice of Prandtl and Nusselt empirical correlation. The fluid flow description in the boundary layer was refined in such a way, that the heat flux, exchanged between the solid and fluid, is obtained directly from Fourier law. The governing equations are based on the local thermodynamic equilibrium and conservation equation of mass, momentum and energy. In order to solve the set of governing equations, the finite-volume method is used. This procedure gives rapid answers whether the proposed geometry satisfies the design criteria. (C) 2003 Elsevier B.V. All rights reserved.",
journal = "Nuclear Instruments and Methods in Physics Research. Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment",
title = "Modeling of thermal properties of a TeO2 target for radioiodine production",
volume = "521",
number = "1",
pages = "161-170",
doi = "10.1016/j.nima.2003.11.147"
}

Čomor, J. J., Stevanović, Ž. M., Rajcevic, M.,& Košutić, D. D.. (2004). Modeling of thermal properties of a TeO2 target for radioiodine production. in Nuclear Instruments and Methods in Physics Research. Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment, 521(1), 161-170.
https://doi.org/10.1016/j.nima.2003.11.147

Čomor JJ, Stevanović ŽM, Rajcevic M, Košutić DD. Modeling of thermal properties of a TeO2 target for radioiodine production. in Nuclear Instruments and Methods in Physics Research. Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment. 2004;521(1):161-170.
doi:10.1016/j.nima.2003.11.147 .

Čomor, Jožef J., Stevanović, Žarko M., Rajcevic, M, Košutić, Duško D., "Modeling of thermal properties of a TeO2 target for radioiodine production" in Nuclear Instruments and Methods in Physics Research. Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment, 521, no. 1 (2004):161-170,
https://doi.org/10.1016/j.nima.2003.11.147 . .

TY  - JOUR
AU  - Beyer, GJ
AU  - Miederer, M
AU  - Vranješ-Đurić, Sanja
AU  - Čomor, Jožef J.
AU  - Kunzi, G
AU  - Hartley, O
AU  - Senekowitsch-Schmidtke, R
AU  - Soloviev, D
AU  - Buchegger, F
PY  - 2004
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2757
AB  - This study demonstrates high-efficiency sterilisation of single cancer cells in a SCID mouse model of leukaemia using rituximab, a monoclonal antibody that targets CD20, labelled with terbium-149, an alpha-emitting radionuclide. Radio-immunotherapy with 5.5 MBq labelled antibody conjugate (1.11 GBq/mg) 2 days after an intravenous graft of 5.10(6) Daudi cells resulted in tumour-free survival for GT 120 days in 89% of treated animals. In contrast, all control mice (no treatment or treated with 5 or 300 mug unlabelled rituximab) developed lymphoma disease. At the end of the study period, 28.4%+/-4% of the long-lived daughter activity remained in the body, of which 91.1% was located in bone tissue and 6.3% in the liver. A relatively high daughter radioactivity concentration was found in the spleen (12%+/-2%/g), suggesting that the killed cancer cells are mainly eliminated through the spleen. This promising preliminary in vivo study suggests that targeted alpha therapy with Tb-149 is worthy of consideration as a new-generation radio-immunotherapeutic approach.
T2  - European Journal of Nuclear Medicine and Molecular Imaging
T1  - Targeted alpha therapy in vivo: direct evidence for single cancer cell kill using Tb-149-rituximab
VL  - 31
IS  - 4
SP  - 547
EP  - 554
DO  - 10.1007/s00259-003-1413-9
ER  - 

@article{
author = "Beyer, GJ and Miederer, M and Vranješ-Đurić, Sanja and Čomor, Jožef J. and Kunzi, G and Hartley, O and Senekowitsch-Schmidtke, R and Soloviev, D and Buchegger, F",
year = "2004",
abstract = "This study demonstrates high-efficiency sterilisation of single cancer cells in a SCID mouse model of leukaemia using rituximab, a monoclonal antibody that targets CD20, labelled with terbium-149, an alpha-emitting radionuclide. Radio-immunotherapy with 5.5 MBq labelled antibody conjugate (1.11 GBq/mg) 2 days after an intravenous graft of 5.10(6) Daudi cells resulted in tumour-free survival for GT 120 days in 89% of treated animals. In contrast, all control mice (no treatment or treated with 5 or 300 mug unlabelled rituximab) developed lymphoma disease. At the end of the study period, 28.4%+/-4% of the long-lived daughter activity remained in the body, of which 91.1% was located in bone tissue and 6.3% in the liver. A relatively high daughter radioactivity concentration was found in the spleen (12%+/-2%/g), suggesting that the killed cancer cells are mainly eliminated through the spleen. This promising preliminary in vivo study suggests that targeted alpha therapy with Tb-149 is worthy of consideration as a new-generation radio-immunotherapeutic approach.",
journal = "European Journal of Nuclear Medicine and Molecular Imaging",
title = "Targeted alpha therapy in vivo: direct evidence for single cancer cell kill using Tb-149-rituximab",
volume = "31",
number = "4",
pages = "547-554",
doi = "10.1007/s00259-003-1413-9"
}

Beyer, G., Miederer, M., Vranješ-Đurić, S., Čomor, J. J., Kunzi, G., Hartley, O., Senekowitsch-Schmidtke, R., Soloviev, D.,& Buchegger, F.. (2004). Targeted alpha therapy in vivo: direct evidence for single cancer cell kill using Tb-149-rituximab. in European Journal of Nuclear Medicine and Molecular Imaging, 31(4), 547-554.
https://doi.org/10.1007/s00259-003-1413-9

Beyer G, Miederer M, Vranješ-Đurić S, Čomor JJ, Kunzi G, Hartley O, Senekowitsch-Schmidtke R, Soloviev D, Buchegger F. Targeted alpha therapy in vivo: direct evidence for single cancer cell kill using Tb-149-rituximab. in European Journal of Nuclear Medicine and Molecular Imaging. 2004;31(4):547-554.
doi:10.1007/s00259-003-1413-9 .

Beyer, GJ, Miederer, M, Vranješ-Đurić, Sanja, Čomor, Jožef J., Kunzi, G, Hartley, O, Senekowitsch-Schmidtke, R, Soloviev, D, Buchegger, F, "Targeted alpha therapy in vivo: direct evidence for single cancer cell kill using Tb-149-rituximab" in European Journal of Nuclear Medicine and Molecular Imaging, 31, no. 4 (2004):547-554,
https://doi.org/10.1007/s00259-003-1413-9 . .

TY  - JOUR
AU  - Nešković, Nebojša B.
AU  - Ristić-Đurović, Jasna L.
AU  - Vorojtsov, SB
AU  - Beličev, Petar
AU  - Ivanenko, IA
AU  - Cirkovic, S
AU  - Vorozhtsov, AS
AU  - Bojović, Boško
AU  - Dobrosavljević, Aleksandar S.
AU  - Vujović, Velibor V.
AU  - Čomor, Jožef J.
AU  - Pajović, Snežana B.
PY  - 2003
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/6381
AB  - The VINCY Cyclotron is the main part of the TESLA Accelerator Installation. The diameter of the pole of this machine is 2000 mm. Its bending constant is 145 MeV while its focusing constant is 75 MeV. The radiofrequency system of the machine consists of two lambda/4-resonators with the eigenfrequency in the range from 17 to 31 MHz. Ions coming from a heavy ion source or a light ion source will be injected into the machine axially. They will be introduced into its median plane by a spiral inflector. Heavy ions accelerated in the machine will be extracted from it by a foil stripping system or by an electrostatic deflection system. Light ions will be extracted from it by the foil stripping system. The first programs of use of the VINCY Cyclotron are related to routine and experimental production of radioisotopes and radiopharmaceuticals, and to biomedical research with ion beams. The first beam extracted from the machine will be the proton beam of the energy of 22 MeV obtained from the H-2(+) beam extracted from the light ion source. This beam will be used first for production of radioisotope F-18 and radiopharmaceutical (18)FDG, to be employed for positron emission tomography.
T2  - Nukleonika
T1  - Status report of the VINCY cyclotron
VL  - 48
SP  - S135
EP  - S139
UR  - https://hdl.handle.net/21.15107/rcub_vinar_6381
ER  - 

@article{
author = "Nešković, Nebojša B. and Ristić-Đurović, Jasna L. and Vorojtsov, SB and Beličev, Petar and Ivanenko, IA and Cirkovic, S and Vorozhtsov, AS and Bojović, Boško and Dobrosavljević, Aleksandar S. and Vujović, Velibor V. and Čomor, Jožef J. and Pajović, Snežana B.",
year = "2003",
abstract = "The VINCY Cyclotron is the main part of the TESLA Accelerator Installation. The diameter of the pole of this machine is 2000 mm. Its bending constant is 145 MeV while its focusing constant is 75 MeV. The radiofrequency system of the machine consists of two lambda/4-resonators with the eigenfrequency in the range from 17 to 31 MHz. Ions coming from a heavy ion source or a light ion source will be injected into the machine axially. They will be introduced into its median plane by a spiral inflector. Heavy ions accelerated in the machine will be extracted from it by a foil stripping system or by an electrostatic deflection system. Light ions will be extracted from it by the foil stripping system. The first programs of use of the VINCY Cyclotron are related to routine and experimental production of radioisotopes and radiopharmaceuticals, and to biomedical research with ion beams. The first beam extracted from the machine will be the proton beam of the energy of 22 MeV obtained from the H-2(+) beam extracted from the light ion source. This beam will be used first for production of radioisotope F-18 and radiopharmaceutical (18)FDG, to be employed for positron emission tomography.",
journal = "Nukleonika",
title = "Status report of the VINCY cyclotron",
volume = "48",
pages = "S135-S139",
url = "https://hdl.handle.net/21.15107/rcub_vinar_6381"
}

Nešković, N. B., Ristić-Đurović, J. L., Vorojtsov, S., Beličev, P., Ivanenko, I., Cirkovic, S., Vorozhtsov, A., Bojović, B., Dobrosavljević, A. S., Vujović, V. V., Čomor, J. J.,& Pajović, S. B.. (2003). Status report of the VINCY cyclotron. in Nukleonika, 48, S135-S139.
https://hdl.handle.net/21.15107/rcub_vinar_6381

Nešković NB, Ristić-Đurović JL, Vorojtsov S, Beličev P, Ivanenko I, Cirkovic S, Vorozhtsov A, Bojović B, Dobrosavljević AS, Vujović VV, Čomor JJ, Pajović SB. Status report of the VINCY cyclotron. in Nukleonika. 2003;48:S135-S139.
https://hdl.handle.net/21.15107/rcub_vinar_6381 .

Nešković, Nebojša B., Ristić-Đurović, Jasna L., Vorojtsov, SB, Beličev, Petar, Ivanenko, IA, Cirkovic, S, Vorozhtsov, AS, Bojović, Boško, Dobrosavljević, Aleksandar S., Vujović, Velibor V., Čomor, Jožef J., Pajović, Snežana B., "Status report of the VINCY cyclotron" in Nukleonika, 48 (2003):S135-S139,
https://hdl.handle.net/21.15107/rcub_vinar_6381 .

TY  - JOUR
AU  - Miederer, M
AU  - Seidl, C
AU  - Beyer, GJ
AU  - Charlton, DE
AU  - Vranješ-Đurić, Sanja
AU  - Čomor, Jožef J.
AU  - Huber, R
AU  - Nikula, T
AU  - Apostolidis, C
AU  - Schuhmacher, C
AU  - Becker, KF
AU  - Senekowitsch-Schmidtke, R
PY  - 2003
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2630
AB  - We investigated the effects of the a-particle emitters Tb-149 and Bi-213 coupled to a tumor-specific antibody targeting the mutated delta 9 E-cadherin (d9 E-Cad) on single cells and cell pellets. The d9 mutation of the adhesion molecule E-cadherin is found in 10% of diffuse-type gastric cancers and is not expressed in normal tissue. Human breast cancer cells (MDA-MB-435S) transfected with d9 E-Cad or the wild-type E-cadherin gene were used to study the effects of anti-d9 E-Cad MAb coupled to Tb-149 and Bi-213 (Tb-149-d9 MAb and Bi-213-d9 MAb). The density of binding sites determined on transfected MDA tumor cells by Scatchard analysis and flow cytometry varied from 4 x 10(4) to 6 x 10(4) antigens per cell. Internalization of radioimmunoconjugates by cells expressing d9 E-Cad was less than 10% of bound antibody within 240 min. The effect of the radioimmunoconjugates on cell suspensions and cell pellets was quantified by [H-3]thymidine incorporation, and the dose to the cell nuclei was determined using microdosimetric calculations. Tb-149 and Bi-213 immunoconjugates affected cells in suspension similarly. Significant differences in the proliferation capacity of d9 E-cadherin- and wildtype E-cadherin-expressing cells were observed at activity concentrations around 185 kBq/ml, corresponding to antibody concentrations between 200 ng/ml and 1000 ng/ml. Proliferation after incubation with Bi-213-d9 MAb was 50% greater in pelleted wild-type E-Cad-expressing cells compared to wildtype E-Cad cells in suspension. In contrast, the proliferation of pelleted d9 E-Cad cells was similar to that of d9 E-Cad cells in suspension. For Tb-149-d9 MAb, no significant difference was found between pelleted cells and cells in suspension for low activity concentrations. However, at high activity concentrations, Tb-149-d9 MAb had only a small effect on pelleted cells. These in vitro studies demonstrate different effects of Tb-149 and Bi-213 conjugated to a tumor-specific antibody toward single cells and tumor cell pellets. Microdosimetric simulation of single cell survival after a-particle irradiation modeled the experimental results with reasonable accuracy. (C) 2003 by Radiation Research Society.
T2  - Radiation Research
T1  - Comparison of the radiotoxicity of two alpha-particle-emitting immunoconjugates, terbium-149 and bismuth-213, directed against a tumor-specific, exon 9 deleted (d9) E-cadherin adhesion protein
VL  - 159
IS  - 5
SP  - 612
EP  - 620
DO  - 10.1667/0033-7587(2003)159[0612:COTROT]2.0.CO;2
ER  - 

@article{
author = "Miederer, M and Seidl, C and Beyer, GJ and Charlton, DE and Vranješ-Đurić, Sanja and Čomor, Jožef J. and Huber, R and Nikula, T and Apostolidis, C and Schuhmacher, C and Becker, KF and Senekowitsch-Schmidtke, R",
year = "2003",
abstract = "We investigated the effects of the a-particle emitters Tb-149 and Bi-213 coupled to a tumor-specific antibody targeting the mutated delta 9 E-cadherin (d9 E-Cad) on single cells and cell pellets. The d9 mutation of the adhesion molecule E-cadherin is found in 10% of diffuse-type gastric cancers and is not expressed in normal tissue. Human breast cancer cells (MDA-MB-435S) transfected with d9 E-Cad or the wild-type E-cadherin gene were used to study the effects of anti-d9 E-Cad MAb coupled to Tb-149 and Bi-213 (Tb-149-d9 MAb and Bi-213-d9 MAb). The density of binding sites determined on transfected MDA tumor cells by Scatchard analysis and flow cytometry varied from 4 x 10(4) to 6 x 10(4) antigens per cell. Internalization of radioimmunoconjugates by cells expressing d9 E-Cad was less than 10% of bound antibody within 240 min. The effect of the radioimmunoconjugates on cell suspensions and cell pellets was quantified by [H-3]thymidine incorporation, and the dose to the cell nuclei was determined using microdosimetric calculations. Tb-149 and Bi-213 immunoconjugates affected cells in suspension similarly. Significant differences in the proliferation capacity of d9 E-cadherin- and wildtype E-cadherin-expressing cells were observed at activity concentrations around 185 kBq/ml, corresponding to antibody concentrations between 200 ng/ml and 1000 ng/ml. Proliferation after incubation with Bi-213-d9 MAb was 50% greater in pelleted wild-type E-Cad-expressing cells compared to wildtype E-Cad cells in suspension. In contrast, the proliferation of pelleted d9 E-Cad cells was similar to that of d9 E-Cad cells in suspension. For Tb-149-d9 MAb, no significant difference was found between pelleted cells and cells in suspension for low activity concentrations. However, at high activity concentrations, Tb-149-d9 MAb had only a small effect on pelleted cells. These in vitro studies demonstrate different effects of Tb-149 and Bi-213 conjugated to a tumor-specific antibody toward single cells and tumor cell pellets. Microdosimetric simulation of single cell survival after a-particle irradiation modeled the experimental results with reasonable accuracy. (C) 2003 by Radiation Research Society.",
journal = "Radiation Research",
title = "Comparison of the radiotoxicity of two alpha-particle-emitting immunoconjugates, terbium-149 and bismuth-213, directed against a tumor-specific, exon 9 deleted (d9) E-cadherin adhesion protein",
volume = "159",
number = "5",
pages = "612-620",
doi = "10.1667/0033-7587(2003)159[0612:COTROT]2.0.CO;2"
}

Miederer, M., Seidl, C., Beyer, G., Charlton, D., Vranješ-Đurić, S., Čomor, J. J., Huber, R., Nikula, T., Apostolidis, C., Schuhmacher, C., Becker, K.,& Senekowitsch-Schmidtke, R.. (2003). Comparison of the radiotoxicity of two alpha-particle-emitting immunoconjugates, terbium-149 and bismuth-213, directed against a tumor-specific, exon 9 deleted (d9) E-cadherin adhesion protein. in Radiation Research, 159(5), 612-620.
https://doi.org/10.1667/0033-7587(2003)159[0612:COTROT]2.0.CO;2

Miederer M, Seidl C, Beyer G, Charlton D, Vranješ-Đurić S, Čomor JJ, Huber R, Nikula T, Apostolidis C, Schuhmacher C, Becker K, Senekowitsch-Schmidtke R. Comparison of the radiotoxicity of two alpha-particle-emitting immunoconjugates, terbium-149 and bismuth-213, directed against a tumor-specific, exon 9 deleted (d9) E-cadherin adhesion protein. in Radiation Research. 2003;159(5):612-620.
doi:10.1667/0033-7587(2003)159[0612:COTROT]2.0.CO;2 .

Miederer, M, Seidl, C, Beyer, GJ, Charlton, DE, Vranješ-Đurić, Sanja, Čomor, Jožef J., Huber, R, Nikula, T, Apostolidis, C, Schuhmacher, C, Becker, KF, Senekowitsch-Schmidtke, R, "Comparison of the radiotoxicity of two alpha-particle-emitting immunoconjugates, terbium-149 and bismuth-213, directed against a tumor-specific, exon 9 deleted (d9) E-cadherin adhesion protein" in Radiation Research, 159, no. 5 (2003):612-620,
https://doi.org/10.1667/0033-7587(2003)159[0612:COTROT]2.0.CO;2 . .

TY  - JOUR
AU  - Trtić-Petrović, Tatjana M.
AU  - Vladisavljević, Goran T.
AU  - Tesic, M
AU  - Kumrić, Ksenija
AU  - Čomor, Jožef J.
PY  - 2002
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/6338
AB  - The development of concentration boundary layer (CBL) inside the hollow fibers, based on the experimental data from membrane-based solvent extraction of thallium (III) from chloride-containing acidic solutions with butyl acetate, was investigated. The experiments have been performed using three laboratory made contactors, consisting of hydrophobic polypropylene or polyvinylidene fluoride fibers of different length. The feed solution flowed inside the fibers, while the organic phase was pumped counter-currently at the module shell side. The influence of aqueous flow rate on the mean mass transfer coefficient in the aqueous phase was investigated. The tube-side Sherwood number was proportional to the Graetz number raised to powers ranging between 0.4 and 0.81. A model for the determination of CBL thickness and entry length was developed and used for the numerical analysis of the process. The entry length, i.e. the axial distance from the fiber inlet at which CBL reaches the axis of the fibers, was directly proportional to the aqueous phase flow rate and inversely proportional to the number of fibers in a module.
T2  - Desalination
T1  - Analysis of concentration boundary layer in thallium (III) extraction with butyl acetate using membrane modules of different length
VL  - 148
IS  - 1-3
SP  - 241
EP  - 246
DO  - 10.1016/S0011-9164(02)00704-X
ER  - 

@article{
author = "Trtić-Petrović, Tatjana M. and Vladisavljević, Goran T. and Tesic, M and Kumrić, Ksenija and Čomor, Jožef J.",
year = "2002",
abstract = "The development of concentration boundary layer (CBL) inside the hollow fibers, based on the experimental data from membrane-based solvent extraction of thallium (III) from chloride-containing acidic solutions with butyl acetate, was investigated. The experiments have been performed using three laboratory made contactors, consisting of hydrophobic polypropylene or polyvinylidene fluoride fibers of different length. The feed solution flowed inside the fibers, while the organic phase was pumped counter-currently at the module shell side. The influence of aqueous flow rate on the mean mass transfer coefficient in the aqueous phase was investigated. The tube-side Sherwood number was proportional to the Graetz number raised to powers ranging between 0.4 and 0.81. A model for the determination of CBL thickness and entry length was developed and used for the numerical analysis of the process. The entry length, i.e. the axial distance from the fiber inlet at which CBL reaches the axis of the fibers, was directly proportional to the aqueous phase flow rate and inversely proportional to the number of fibers in a module.",
journal = "Desalination",
title = "Analysis of concentration boundary layer in thallium (III) extraction with butyl acetate using membrane modules of different length",
volume = "148",
number = "1-3",
pages = "241-246",
doi = "10.1016/S0011-9164(02)00704-X"
}

Trtić-Petrović, T. M., Vladisavljević, G. T., Tesic, M., Kumrić, K.,& Čomor, J. J.. (2002). Analysis of concentration boundary layer in thallium (III) extraction with butyl acetate using membrane modules of different length. in Desalination, 148(1-3), 241-246.
https://doi.org/10.1016/S0011-9164(02)00704-X

Trtić-Petrović TM, Vladisavljević GT, Tesic M, Kumrić K, Čomor JJ. Analysis of concentration boundary layer in thallium (III) extraction with butyl acetate using membrane modules of different length. in Desalination. 2002;148(1-3):241-246.
doi:10.1016/S0011-9164(02)00704-X .

Trtić-Petrović, Tatjana M., Vladisavljević, Goran T., Tesic, M, Kumrić, Ksenija, Čomor, Jožef J., "Analysis of concentration boundary layer in thallium (III) extraction with butyl acetate using membrane modules of different length" in Desalination, 148, no. 1-3 (2002):241-246,
https://doi.org/10.1016/S0011-9164(02)00704-X . .

TY  - JOUR
AU  - Čomor, Jožef J.
AU  - Dakovic, M
AU  - Rajcevic, M
AU  - Košutić, Duško D.
AU  - Spasic, M
AU  - Vidovic, A
AU  - Duricic, J
AU  - Nedeljković, N.
PY  - 2002
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/6328
AB  - According to the concept of the TESLA Accelerator Installation, the channel for production of radioisotopes has to routinely produce Tl-201, In-111, Ga-67, I-123 and F-18, and a number of other radionuclides for experimental purposes. The production of I-123 and F-18 will be performed in dedicated, commercial target stations, while a versatile solid target irradiation system is designed for the routine and experimental production of all other radioisotopes. The solid target station is designed to accept targets for both the 7degrees and 90degrees irradiation geometry. The targets used for the routine production will be prepared by electroplating on a silver substrate. They can be irradiated with a 1.5 kW beam using the 7degrees geometry. The cooling of these targets is enhanced by fins on the back of the silver substrate designed so that the highest temperature on the surface of the target does not exceed 110degreesC. The irradiation procedures will conform to the GMP requirements for the production of radio pharmaceuticals. The irradiated targets will be transported directly into the appropriate hot cell for radiochemical processing, All cells will be equipped with a target dissolution unit for etching the irradiated, electroplated film. After decontamination and sufficient cooling down, these targets will be reused several times. (C) 2001 Elsevier Science B.V. All rights reserved.
T2  - Nuclear Instruments and Methods in Physics Research. Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment
T1  - Solid targetry at the TESLA Accelerator Installation
VL  - 480
IS  - 1
SP  - 7
EP  - 15
DO  - 10.1016/S0168-9002(01)02040-X
ER  - 

@article{
author = "Čomor, Jožef J. and Dakovic, M and Rajcevic, M and Košutić, Duško D. and Spasic, M and Vidovic, A and Duricic, J and Nedeljković, N.",
year = "2002",
abstract = "According to the concept of the TESLA Accelerator Installation, the channel for production of radioisotopes has to routinely produce Tl-201, In-111, Ga-67, I-123 and F-18, and a number of other radionuclides for experimental purposes. The production of I-123 and F-18 will be performed in dedicated, commercial target stations, while a versatile solid target irradiation system is designed for the routine and experimental production of all other radioisotopes. The solid target station is designed to accept targets for both the 7degrees and 90degrees irradiation geometry. The targets used for the routine production will be prepared by electroplating on a silver substrate. They can be irradiated with a 1.5 kW beam using the 7degrees geometry. The cooling of these targets is enhanced by fins on the back of the silver substrate designed so that the highest temperature on the surface of the target does not exceed 110degreesC. The irradiation procedures will conform to the GMP requirements for the production of radio pharmaceuticals. The irradiated targets will be transported directly into the appropriate hot cell for radiochemical processing, All cells will be equipped with a target dissolution unit for etching the irradiated, electroplated film. After decontamination and sufficient cooling down, these targets will be reused several times. (C) 2001 Elsevier Science B.V. All rights reserved.",
journal = "Nuclear Instruments and Methods in Physics Research. Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment",
title = "Solid targetry at the TESLA Accelerator Installation",
volume = "480",
number = "1",
pages = "7-15",
doi = "10.1016/S0168-9002(01)02040-X"
}

Čomor, J. J., Dakovic, M., Rajcevic, M., Košutić, D. D., Spasic, M., Vidovic, A., Duricic, J.,& Nedeljković, N.. (2002). Solid targetry at the TESLA Accelerator Installation. in Nuclear Instruments and Methods in Physics Research. Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment, 480(1), 7-15.
https://doi.org/10.1016/S0168-9002(01)02040-X

Čomor JJ, Dakovic M, Rajcevic M, Košutić DD, Spasic M, Vidovic A, Duricic J, Nedeljković N. Solid targetry at the TESLA Accelerator Installation. in Nuclear Instruments and Methods in Physics Research. Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment. 2002;480(1):7-15.
doi:10.1016/S0168-9002(01)02040-X .

Čomor, Jožef J., Dakovic, M, Rajcevic, M, Košutić, Duško D., Spasic, M, Vidovic, A, Duricic, J, Nedeljković, N., "Solid targetry at the TESLA Accelerator Installation" in Nuclear Instruments and Methods in Physics Research. Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment, 480, no. 1 (2002):7-15,
https://doi.org/10.1016/S0168-9002(01)02040-X . .

TY  - JOUR
AU  - Beyer, GJ
AU  - Čomor, Jožef J.
AU  - Dakovic, M
AU  - Soloviev, D
AU  - Tamburella, C
AU  - Hagebo, E
AU  - Allan, B
AU  - Dmitriev, SN
AU  - Zaitseva, NG
AU  - Starodub, GY
AU  - Molokanova, LG
AU  - Vranješ, Sanja
AU  - Miederer, M
AU  - ISOLDE Collaboration
PY  - 2002
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2520
AB  - The partial alpha emitting lanthanide isotope Tb-149 seems to have a great potential in systemic radioimmuno therapy (RIT), especially when single cells in transit or circulation are targeted. The isotope Tb-149 has a half life of 4.118h and decays by alpha emission (3.97MeV, 17%) EC-process (76%) and beta(+)-emission (7%). In this paper. we analyze the possible production routes: light- and heavy ion induced nuclear reactions and p-induced spallation. The excitation functions for light- and heavy ion induced reactions have been calculated using the ALICE91 code. The direct nuclear reaction Gd-152 (p, 4n) Tb-149 was found to be the most promising production path. Alternatively, the indirect reaction Nd-142 (C-12 5n) Dy-149 -- GT Tb-149 seems to be much more suitable compared to the reaction on the mono-isotopic target element Pr-141 (C-12, 4n) Tb-149. In this case, both, the production yield of Tb-149 and the radionuclidic purity are considerably lower, compared to the (p, 4n)-reaction. In preliminary experiments we produced Tb-149 via the indirect reaction Nd (C-12, 5n) Dy-149 -- GT Tb-149 (108 MeV C-12(+6) ions and 1 particle-muA) at the U-200 heavy ion cyclotron at the FLNR of the JINR Dubna. From a 1.25 It irradiation of a 12 mg/cm(2) (Nd2O3)-Nd-nat target, we obtained 2.7 MBq of Tb-149 (70 muCi) at 20 min EOB. This allows the conclusion, that a dedicated cyclotron equipped with a modem ECR-ion source, providing high ion currents would allow the continuous production of batches of the order of 10-20 GBq of Tb-149 for routine RI-therapy. The lower cross section of the spallation process can be compensated by using very thick targets. On-line mass separation technique provides high purity isotopically clean Tb-149 preparations, independently on the production route chosen. At the ISOLDE facility at CERN, we prepared batches of up to 500 MBq Tb-149 by combining on-line mass separation process followed by a cation exchange chromatography process using alpha-HIBA as eluent. The obtained Tb-149 preparations showed excellent behavior in labeling of chelated monoclonal antibodies.
T2  - Radiochimica Acta
T1  - Production routes of the alpha emitting Tb-149 for medical application
VL  - 90
IS  - 5
SP  - 247
EP  - 252
DO  - 10.1524/ract.2002.90.5_2002.247
ER  - 

@article{
author = "Beyer, GJ and Čomor, Jožef J. and Dakovic, M and Soloviev, D and Tamburella, C and Hagebo, E and Allan, B and Dmitriev, SN and Zaitseva, NG and Starodub, GY and Molokanova, LG and Vranješ, Sanja and Miederer, M and ISOLDE Collaboration",
year = "2002",
abstract = "The partial alpha emitting lanthanide isotope Tb-149 seems to have a great potential in systemic radioimmuno therapy (RIT), especially when single cells in transit or circulation are targeted. The isotope Tb-149 has a half life of 4.118h and decays by alpha emission (3.97MeV, 17%) EC-process (76%) and beta(+)-emission (7%). In this paper. we analyze the possible production routes: light- and heavy ion induced nuclear reactions and p-induced spallation. The excitation functions for light- and heavy ion induced reactions have been calculated using the ALICE91 code. The direct nuclear reaction Gd-152 (p, 4n) Tb-149 was found to be the most promising production path. Alternatively, the indirect reaction Nd-142 (C-12 5n) Dy-149 -- GT Tb-149 seems to be much more suitable compared to the reaction on the mono-isotopic target element Pr-141 (C-12, 4n) Tb-149. In this case, both, the production yield of Tb-149 and the radionuclidic purity are considerably lower, compared to the (p, 4n)-reaction. In preliminary experiments we produced Tb-149 via the indirect reaction Nd (C-12, 5n) Dy-149 -- GT Tb-149 (108 MeV C-12(+6) ions and 1 particle-muA) at the U-200 heavy ion cyclotron at the FLNR of the JINR Dubna. From a 1.25 It irradiation of a 12 mg/cm(2) (Nd2O3)-Nd-nat target, we obtained 2.7 MBq of Tb-149 (70 muCi) at 20 min EOB. This allows the conclusion, that a dedicated cyclotron equipped with a modem ECR-ion source, providing high ion currents would allow the continuous production of batches of the order of 10-20 GBq of Tb-149 for routine RI-therapy. The lower cross section of the spallation process can be compensated by using very thick targets. On-line mass separation technique provides high purity isotopically clean Tb-149 preparations, independently on the production route chosen. At the ISOLDE facility at CERN, we prepared batches of up to 500 MBq Tb-149 by combining on-line mass separation process followed by a cation exchange chromatography process using alpha-HIBA as eluent. The obtained Tb-149 preparations showed excellent behavior in labeling of chelated monoclonal antibodies.",
journal = "Radiochimica Acta",
title = "Production routes of the alpha emitting Tb-149 for medical application",
volume = "90",
number = "5",
pages = "247-252",
doi = "10.1524/ract.2002.90.5_2002.247"
}

Beyer, G., Čomor, J. J., Dakovic, M., Soloviev, D., Tamburella, C., Hagebo, E., Allan, B., Dmitriev, S., Zaitseva, N., Starodub, G., Molokanova, L., Vranješ, S., Miederer, M.,& ISOLDE Collaboration. (2002). Production routes of the alpha emitting Tb-149 for medical application. in Radiochimica Acta, 90(5), 247-252.
https://doi.org/10.1524/ract.2002.90.5_2002.247

Beyer G, Čomor JJ, Dakovic M, Soloviev D, Tamburella C, Hagebo E, Allan B, Dmitriev S, Zaitseva N, Starodub G, Molokanova L, Vranješ S, Miederer M, ISOLDE Collaboration. Production routes of the alpha emitting Tb-149 for medical application. in Radiochimica Acta. 2002;90(5):247-252.
doi:10.1524/ract.2002.90.5_2002.247 .

Beyer, GJ, Čomor, Jožef J., Dakovic, M, Soloviev, D, Tamburella, C, Hagebo, E, Allan, B, Dmitriev, SN, Zaitseva, NG, Starodub, GY, Molokanova, LG, Vranješ, Sanja, Miederer, M, ISOLDE Collaboration, "Production routes of the alpha emitting Tb-149 for medical application" in Radiochimica Acta, 90, no. 5 (2002):247-252,
https://doi.org/10.1524/ract.2002.90.5_2002.247 . .

TY  - JOUR
AU  - Čomor, Jožef J.
AU  - Petković, Đorđe M.
PY  - 2001
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2446
AB  - Extraction of uranyl nitrate, chloride and sulphate with tri-n-octyl amine (TOA) in benzene as a function of the TOA concentration has been studied. The concentration based extraction equilibrium constants were calculated from the distribution data of the uranyl salts, fitting the parameters of a chemical model to the experimentally obtained extraction isotherms. The calculated equilibrium constants are 46.5, 89.4 and 4.2x 10(4) for uranyl nitrate, chloride and sulphate, respectively. These values are in good agreement with the previously reported extraction equilibrium constants calculated by the inflection point method.
T2  - Journal of the Serbian Chemical Society
T1  - Extraction of uranyl nitrate, sulphate and chloride with tri-n-octyl amine (TOA) from aqueous solutions
VL  - 66
IS  - 7
SP  - 443
EP  - 449
UR  - https://hdl.handle.net/21.15107/rcub_vinar_2446
ER  - 

@article{
author = "Čomor, Jožef J. and Petković, Đorđe M.",
year = "2001",
abstract = "Extraction of uranyl nitrate, chloride and sulphate with tri-n-octyl amine (TOA) in benzene as a function of the TOA concentration has been studied. The concentration based extraction equilibrium constants were calculated from the distribution data of the uranyl salts, fitting the parameters of a chemical model to the experimentally obtained extraction isotherms. The calculated equilibrium constants are 46.5, 89.4 and 4.2x 10(4) for uranyl nitrate, chloride and sulphate, respectively. These values are in good agreement with the previously reported extraction equilibrium constants calculated by the inflection point method.",
journal = "Journal of the Serbian Chemical Society",
title = "Extraction of uranyl nitrate, sulphate and chloride with tri-n-octyl amine (TOA) from aqueous solutions",
volume = "66",
number = "7",
pages = "443-449",
url = "https://hdl.handle.net/21.15107/rcub_vinar_2446"
}

Čomor, J. J.,& Petković, Đ. M.. (2001). Extraction of uranyl nitrate, sulphate and chloride with tri-n-octyl amine (TOA) from aqueous solutions. in Journal of the Serbian Chemical Society, 66(7), 443-449.
https://hdl.handle.net/21.15107/rcub_vinar_2446

Čomor JJ, Petković ĐM. Extraction of uranyl nitrate, sulphate and chloride with tri-n-octyl amine (TOA) from aqueous solutions. in Journal of the Serbian Chemical Society. 2001;66(7):443-449.
https://hdl.handle.net/21.15107/rcub_vinar_2446 .

Čomor, Jožef J., Petković, Đorđe M., "Extraction of uranyl nitrate, sulphate and chloride with tri-n-octyl amine (TOA) from aqueous solutions" in Journal of the Serbian Chemical Society, 66, no. 7 (2001):443-449,
https://hdl.handle.net/21.15107/rcub_vinar_2446 .

TY  - JOUR
AU  - Trtić-Petrović, Tatjana M.
AU  - Vladisavljević, Goran T.
AU  - Archimandritis, Spyridon
AU  - Varvarigou, A
AU  - Čomor, Jožef J.
PY  - 2001
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2456
AB  - The influence of module arrangements on solvent extraction of thallium(III) from NaCl/H2SO4 solution into butyl acetate has been studied using two laboratory-made modules consisting of hydrophobic polypropylene hollow fibers. The aqueous phase was recirculated between the module(s) and a mixed reservoir, and the organic phase was stagnant on the shell side. It was found that the extraction of Tl([Il) from aqueous phase strictly depends on aqueous flow rate and module arrangement. The results obtained are discussed in terms of the fraction of TI(III) removed from the aqueous phase reservoir, the flux of TI(III) through the interfacial area, and the best arrangement of modules for the production process of the radiopharmaceutical (TlCl)-Tl-201.
T2  - Journal of Separation Science
T1  - Influence of module arrangements on solvent extraction of thallium(III) in hollow fiber contactors
VL  - 24
IS  - 7
SP  - 519
EP  - 525
DO  - 10.1002/1615-9314(20010801)24:7 LT 519::AID-JSSC519 GT 3.0.CO;2-N
ER  - 

@article{
author = "Trtić-Petrović, Tatjana M. and Vladisavljević, Goran T. and Archimandritis, Spyridon and Varvarigou, A and Čomor, Jožef J.",
year = "2001",
abstract = "The influence of module arrangements on solvent extraction of thallium(III) from NaCl/H2SO4 solution into butyl acetate has been studied using two laboratory-made modules consisting of hydrophobic polypropylene hollow fibers. The aqueous phase was recirculated between the module(s) and a mixed reservoir, and the organic phase was stagnant on the shell side. It was found that the extraction of Tl([Il) from aqueous phase strictly depends on aqueous flow rate and module arrangement. The results obtained are discussed in terms of the fraction of TI(III) removed from the aqueous phase reservoir, the flux of TI(III) through the interfacial area, and the best arrangement of modules for the production process of the radiopharmaceutical (TlCl)-Tl-201.",
journal = "Journal of Separation Science",
title = "Influence of module arrangements on solvent extraction of thallium(III) in hollow fiber contactors",
volume = "24",
number = "7",
pages = "519-525",
doi = "10.1002/1615-9314(20010801)24:7 LT 519::AID-JSSC519 GT 3.0.CO;2-N"
}

Trtić-Petrović, T. M., Vladisavljević, G. T., Archimandritis, S., Varvarigou, A.,& Čomor, J. J.. (2001). Influence of module arrangements on solvent extraction of thallium(III) in hollow fiber contactors. in Journal of Separation Science, 24(7), 519-525.
https://doi.org/10.1002/1615-9314(20010801)24:7 LT 519::AID-JSSC519 GT 3.0.CO;2-N

Trtić-Petrović TM, Vladisavljević GT, Archimandritis S, Varvarigou A, Čomor JJ. Influence of module arrangements on solvent extraction of thallium(III) in hollow fiber contactors. in Journal of Separation Science. 2001;24(7):519-525.
doi:10.1002/1615-9314(20010801)24:7 LT 519::AID-JSSC519 GT 3.0.CO;2-N .

Trtić-Petrović, Tatjana M., Vladisavljević, Goran T., Archimandritis, Spyridon, Varvarigou, A, Čomor, Jožef J., "Influence of module arrangements on solvent extraction of thallium(III) in hollow fiber contactors" in Journal of Separation Science, 24, no. 7 (2001):519-525,
https://doi.org/10.1002/1615-9314(20010801)24:7 LT 519::AID-JSSC519 GT 3.0.CO;2-N . .

TY  - JOUR
AU  - Trtić, Tatjana M.
AU  - Vladisavljević, Goran T.
AU  - Čomor, Jožef J.
PY  - 2001
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2443
AB  - This paper presents the experimental results of thallium (III) extraction from NaCl/H2SO4 solution with butyl acetate in hollow-fiber membrane contactors. The experiments were performed using laboratory made modules consisting of hydrophobic polypropylene or polyvinylidene fluoride fibers of different effective membrane areas. The aqueous phase was recirculated between the module and a mixed reservoir, and the organic phase was fed at the shell side in once-through mode. The influences of the aqueous and organic phase flow rate on the overall mass transfer coefficient were investigated. The experimental results are discussed in terms of the fraction of Tl(III) removed from the aqueous phase reservoir and the mean Tl(III) flux through the interfacial area. The results can be used for the design of a hollow-fiber contractor based extraction process that can be utilized in production of the radiopharmaceutical (TlCl)-Tl-201.
T2  - Separation Science and Technology
T1  - Single-stage and two-stage solvent extraction of Tl(III) in hollow-fiber contactors under recirculation mode of operation
VL  - 36
IS  - 2
SP  - 295
EP  - 312
DO  - 10.1081/SS-100001080
ER  - 

@article{
author = "Trtić, Tatjana M. and Vladisavljević, Goran T. and Čomor, Jožef J.",
year = "2001",
abstract = "This paper presents the experimental results of thallium (III) extraction from NaCl/H2SO4 solution with butyl acetate in hollow-fiber membrane contactors. The experiments were performed using laboratory made modules consisting of hydrophobic polypropylene or polyvinylidene fluoride fibers of different effective membrane areas. The aqueous phase was recirculated between the module and a mixed reservoir, and the organic phase was fed at the shell side in once-through mode. The influences of the aqueous and organic phase flow rate on the overall mass transfer coefficient were investigated. The experimental results are discussed in terms of the fraction of Tl(III) removed from the aqueous phase reservoir and the mean Tl(III) flux through the interfacial area. The results can be used for the design of a hollow-fiber contractor based extraction process that can be utilized in production of the radiopharmaceutical (TlCl)-Tl-201.",
journal = "Separation Science and Technology",
title = "Single-stage and two-stage solvent extraction of Tl(III) in hollow-fiber contactors under recirculation mode of operation",
volume = "36",
number = "2",
pages = "295-312",
doi = "10.1081/SS-100001080"
}

Trtić, T. M., Vladisavljević, G. T.,& Čomor, J. J.. (2001). Single-stage and two-stage solvent extraction of Tl(III) in hollow-fiber contactors under recirculation mode of operation. in Separation Science and Technology, 36(2), 295-312.
https://doi.org/10.1081/SS-100001080

Trtić TM, Vladisavljević GT, Čomor JJ. Single-stage and two-stage solvent extraction of Tl(III) in hollow-fiber contactors under recirculation mode of operation. in Separation Science and Technology. 2001;36(2):295-312.
doi:10.1081/SS-100001080 .

Trtić, Tatjana M., Vladisavljević, Goran T., Čomor, Jožef J., "Single-stage and two-stage solvent extraction of Tl(III) in hollow-fiber contactors under recirculation mode of operation" in Separation Science and Technology, 36, no. 2 (2001):295-312,
https://doi.org/10.1081/SS-100001080 . .

TY  - JOUR
AU  - Marinkovic, V
AU  - Agbaba, Danica
AU  - Karljiković-Rajić, Katarina
AU  - Čomor, Jožef J.
AU  - Zivanov-Stakic, D
PY  - 2000
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2337
AB  - The photodecomposition of nisoldipine ((+/-)3-isobutyl-5-methyl-1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-pyridine-3,5-dicarboxylate), whereby its 4-(2-nitrosophenyl) pyridine analogue is obtained as the photolytic product, was investigated under daylight exposure by means of UV derivative spectrophotometry. The optimal instrumental parameters (120 nm/min scan speed: 2 nm slit width; Delta lambda = 10 nm and 5 s response time) for analogue derivative spectra were established for amplitudes D-1(285) and D-2(291) (measured to the baseline) of the nitroso analogue assay, as well as for D-1(386) of the parent compound-nisoldipine assay. Using the first-order derivative spectrum, the minimum detectable amount of nitroso analogue in the presence of nisoldipine was equivalent to an impurity level of 5% and by the second-order derivative spectrum, the determination limit was equivalent to an impurity level of 2%. The degradation of nisoldipine followed within 30 days and the calculated maximal degradation rate was 1.6% per day for nisoldipine raw material, but significantly lower values of 0.19 and 0.15% per day were obtained for Nisoldin(R) tablets (10 and 5 mg, respectively). (C) 2000 Elsevier Science S.A. All rights reserved.
T2  - Il Farmaco
T1  - UV derivative spectrophotometric study of the photochemical degradation of nisoldipine
VL  - 55
IS  - 2
SP  - 128
EP  - 133
DO  - 10.1016/S0014-827X(00)00004-5
ER  - 

@article{
author = "Marinkovic, V and Agbaba, Danica and Karljiković-Rajić, Katarina and Čomor, Jožef J. and Zivanov-Stakic, D",
year = "2000",
abstract = "The photodecomposition of nisoldipine ((+/-)3-isobutyl-5-methyl-1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-pyridine-3,5-dicarboxylate), whereby its 4-(2-nitrosophenyl) pyridine analogue is obtained as the photolytic product, was investigated under daylight exposure by means of UV derivative spectrophotometry. The optimal instrumental parameters (120 nm/min scan speed: 2 nm slit width; Delta lambda = 10 nm and 5 s response time) for analogue derivative spectra were established for amplitudes D-1(285) and D-2(291) (measured to the baseline) of the nitroso analogue assay, as well as for D-1(386) of the parent compound-nisoldipine assay. Using the first-order derivative spectrum, the minimum detectable amount of nitroso analogue in the presence of nisoldipine was equivalent to an impurity level of 5% and by the second-order derivative spectrum, the determination limit was equivalent to an impurity level of 2%. The degradation of nisoldipine followed within 30 days and the calculated maximal degradation rate was 1.6% per day for nisoldipine raw material, but significantly lower values of 0.19 and 0.15% per day were obtained for Nisoldin(R) tablets (10 and 5 mg, respectively). (C) 2000 Elsevier Science S.A. All rights reserved.",
journal = "Il Farmaco",
title = "UV derivative spectrophotometric study of the photochemical degradation of nisoldipine",
volume = "55",
number = "2",
pages = "128-133",
doi = "10.1016/S0014-827X(00)00004-5"
}

Marinkovic, V., Agbaba, D., Karljiković-Rajić, K., Čomor, J. J.,& Zivanov-Stakic, D.. (2000). UV derivative spectrophotometric study of the photochemical degradation of nisoldipine. in Il Farmaco, 55(2), 128-133.
https://doi.org/10.1016/S0014-827X(00)00004-5

Marinkovic V, Agbaba D, Karljiković-Rajić K, Čomor JJ, Zivanov-Stakic D. UV derivative spectrophotometric study of the photochemical degradation of nisoldipine. in Il Farmaco. 2000;55(2):128-133.
doi:10.1016/S0014-827X(00)00004-5 .

Marinkovic, V, Agbaba, Danica, Karljiković-Rajić, Katarina, Čomor, Jožef J., Zivanov-Stakic, D, "UV derivative spectrophotometric study of the photochemical degradation of nisoldipine" in Il Farmaco, 55, no. 2 (2000):128-133,
https://doi.org/10.1016/S0014-827X(00)00004-5 . .

TY  - JOUR
AU  - Trtić, Tatjana M.
AU  - Vladisavljević, Goran T.
AU  - Čomor, Jožef J.
PY  - 2000
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2369
AB  - Dispersion-free extraction of thallium(III) from NaCl/H2SO4 solution into butyl acetate has been studied using hydrophobic polypropylene and polyvinylidene fluoride hollow fibers of different effective lengths. The aqueous feed solution flowed inside the fibers and the organic phase was fed at the shell side. The influence of phase flow rates on the mass transfer coefficients was investigated, and correlations between the Sherwood and Graetz numbers were developed. The overall resistance to mass transfer is controlled by the feed-side mass transfer coefficient due to the high partition coefficient of HTlCl4 between the phases. The obtained results are discussed in terms of extraction efficiency, thallium flux through the interfacial area, and the length of the transfer unit as a function of the feed flow rate and the effective fiber length. The extraction efficiency was independent of the organic phase flow rate.
T2  - Separation Science and Technology
T1  - Dispersion-free solvent extraction of thallium(III) in hollow fiber contactors
VL  - 35
IS  - 10
SP  - 1587
EP  - 1601
DO  - 10.1081/SS-100100242
ER  - 

@article{
author = "Trtić, Tatjana M. and Vladisavljević, Goran T. and Čomor, Jožef J.",
year = "2000",
abstract = "Dispersion-free extraction of thallium(III) from NaCl/H2SO4 solution into butyl acetate has been studied using hydrophobic polypropylene and polyvinylidene fluoride hollow fibers of different effective lengths. The aqueous feed solution flowed inside the fibers and the organic phase was fed at the shell side. The influence of phase flow rates on the mass transfer coefficients was investigated, and correlations between the Sherwood and Graetz numbers were developed. The overall resistance to mass transfer is controlled by the feed-side mass transfer coefficient due to the high partition coefficient of HTlCl4 between the phases. The obtained results are discussed in terms of extraction efficiency, thallium flux through the interfacial area, and the length of the transfer unit as a function of the feed flow rate and the effective fiber length. The extraction efficiency was independent of the organic phase flow rate.",
journal = "Separation Science and Technology",
title = "Dispersion-free solvent extraction of thallium(III) in hollow fiber contactors",
volume = "35",
number = "10",
pages = "1587-1601",
doi = "10.1081/SS-100100242"
}

Trtić, T. M., Vladisavljević, G. T.,& Čomor, J. J.. (2000). Dispersion-free solvent extraction of thallium(III) in hollow fiber contactors. in Separation Science and Technology, 35(10), 1587-1601.
https://doi.org/10.1081/SS-100100242

Trtić TM, Vladisavljević GT, Čomor JJ. Dispersion-free solvent extraction of thallium(III) in hollow fiber contactors. in Separation Science and Technology. 2000;35(10):1587-1601.
doi:10.1081/SS-100100242 .

Trtić, Tatjana M., Vladisavljević, Goran T., Čomor, Jožef J., "Dispersion-free solvent extraction of thallium(III) in hollow fiber contactors" in Separation Science and Technology, 35, no. 10 (2000):1587-1601,
https://doi.org/10.1081/SS-100100242 . .

TY  - JOUR
AU  - Čomor, Jožef J.
AU  - Kopečni, Miroslav M.
AU  - Petković, Đorđe M.
PY  - 1999
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2310
AB  - The interact ion of tri-n-butyl phosphate (TBP) with diluents and its self-association have been investigated. The corresponding equilibrium constants were determined and used to calculate the concentration of TBP monomer. The calculated TBP monomer concentrations correspond to the TBP activities published in the literature.
T2  - Journal of the Serbian Chemical Society
T1  - Self-association and association of tri-n-butyl phosphate (TBP) in different diluents
VL  - 64
IS  - 12
SP  - 789
EP  - 793
UR  - https://hdl.handle.net/21.15107/rcub_vinar_2310
ER  - 

@article{
author = "Čomor, Jožef J. and Kopečni, Miroslav M. and Petković, Đorđe M.",
year = "1999",
abstract = "The interact ion of tri-n-butyl phosphate (TBP) with diluents and its self-association have been investigated. The corresponding equilibrium constants were determined and used to calculate the concentration of TBP monomer. The calculated TBP monomer concentrations correspond to the TBP activities published in the literature.",
journal = "Journal of the Serbian Chemical Society",
title = "Self-association and association of tri-n-butyl phosphate (TBP) in different diluents",
volume = "64",
number = "12",
pages = "789-793",
url = "https://hdl.handle.net/21.15107/rcub_vinar_2310"
}

Čomor, J. J., Kopečni, M. M.,& Petković, Đ. M.. (1999). Self-association and association of tri-n-butyl phosphate (TBP) in different diluents. in Journal of the Serbian Chemical Society, 64(12), 789-793.
https://hdl.handle.net/21.15107/rcub_vinar_2310

Čomor JJ, Kopečni MM, Petković ĐM. Self-association and association of tri-n-butyl phosphate (TBP) in different diluents. in Journal of the Serbian Chemical Society. 1999;64(12):789-793.
https://hdl.handle.net/21.15107/rcub_vinar_2310 .

Čomor, Jožef J., Kopečni, Miroslav M., Petković, Đorđe M., "Self-association and association of tri-n-butyl phosphate (TBP) in different diluents" in Journal of the Serbian Chemical Society, 64, no. 12 (1999):789-793,
https://hdl.handle.net/21.15107/rcub_vinar_2310 .

TY  - JOUR
AU  - Čomor, Jožef J.
AU  - Tolic, AS
AU  - Kopečni, Miroslav M.
AU  - Petković, Đorđe M.
PY  - 1999
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2227
AB  - A mathematical model developed for the equilibrium HNO3-UO2(NO3)(2)-tri-n-butyl phosphate (TBP)-diluent is the basis of the computation of distribution isotherms. The isotherms are used to study the influence of TBP concentration on two chosen operation parameters, distribution coefficients and number of theoretical stages, for the selected flow sheets. It is established that an increase in TBP concentration leads to a decrease in the number of theoretical stages for the extraction flow sheets but to their increase for the stripping flow sheets. Given diagrams can be used to determine the efficiency of extraction processes. Agreement with available literature calculations on the number of theoretical stages supports the use of our model in the computation of distribution isotherms, of the system quoted above, in a wide range of nitric acid, uranyl nitrate, and TBP concentrations.
T2  - Separation Science and Technology
T1  - Modeling of the simultaneous extraction of nitric acid and uranyl nitrate with tri-n-butyl phosphate. Application to extraction operation
VL  - 34
IS  - 1
SP  - 115
EP  - 122
DO  - 10.1081/SS-100100640
ER  - 

@article{
author = "Čomor, Jožef J. and Tolic, AS and Kopečni, Miroslav M. and Petković, Đorđe M.",
year = "1999",
abstract = "A mathematical model developed for the equilibrium HNO3-UO2(NO3)(2)-tri-n-butyl phosphate (TBP)-diluent is the basis of the computation of distribution isotherms. The isotherms are used to study the influence of TBP concentration on two chosen operation parameters, distribution coefficients and number of theoretical stages, for the selected flow sheets. It is established that an increase in TBP concentration leads to a decrease in the number of theoretical stages for the extraction flow sheets but to their increase for the stripping flow sheets. Given diagrams can be used to determine the efficiency of extraction processes. Agreement with available literature calculations on the number of theoretical stages supports the use of our model in the computation of distribution isotherms, of the system quoted above, in a wide range of nitric acid, uranyl nitrate, and TBP concentrations.",
journal = "Separation Science and Technology",
title = "Modeling of the simultaneous extraction of nitric acid and uranyl nitrate with tri-n-butyl phosphate. Application to extraction operation",
volume = "34",
number = "1",
pages = "115-122",
doi = "10.1081/SS-100100640"
}

Čomor, J. J., Tolic, A., Kopečni, M. M.,& Petković, Đ. M.. (1999). Modeling of the simultaneous extraction of nitric acid and uranyl nitrate with tri-n-butyl phosphate. Application to extraction operation. in Separation Science and Technology, 34(1), 115-122.
https://doi.org/10.1081/SS-100100640

Čomor JJ, Tolic A, Kopečni MM, Petković ĐM. Modeling of the simultaneous extraction of nitric acid and uranyl nitrate with tri-n-butyl phosphate. Application to extraction operation. in Separation Science and Technology. 1999;34(1):115-122.
doi:10.1081/SS-100100640 .

Čomor, Jožef J., Tolic, AS, Kopečni, Miroslav M., Petković, Đorđe M., "Modeling of the simultaneous extraction of nitric acid and uranyl nitrate with tri-n-butyl phosphate. Application to extraction operation" in Separation Science and Technology, 34, no. 1 (1999):115-122,
https://doi.org/10.1081/SS-100100640 . .

TY  - JOUR
AU  - Trtić, Tatjana M.
AU  - Čomor, Jožef J.
PY  - 1999
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2245
AB  - Experimentally obtained extraction isotherms of the system thallium-sulfuric acid-sodium chloride-butyl acetate are presented. The influence of the sulfuric acid and chloride anion concentrations on the extraction equilibria of thallium was investigated. An increase in the acidity of the aqueous phase results in steeper extraction isotherms, and the amount of thallium extracted generally increases. The influence of chloride anions on the equilibrium is more complex. It was found that the extraction equilibria is not influenced by the chloride ion concentration, provided that the Cl/Tl ratio in the aqueous phase is greater than or equal to 4. If this ratio is less than 4, the concentration of chloride anions significantly influences the extraction isotherms. The results obtained are discussed in terms of the composition of the complex in the organic phase. An apparent reaction constant equation is proposed for the prediction of the extraction equilibria.
T2  - Separation Science and Technology
T1  - Extraction of thallium with butyl acetate
VL  - 34
IS  - 5
SP  - 771
EP  - 779
UR  - https://hdl.handle.net/21.15107/rcub_vinar_2245
ER  - 

@article{
author = "Trtić, Tatjana M. and Čomor, Jožef J.",
year = "1999",
abstract = "Experimentally obtained extraction isotherms of the system thallium-sulfuric acid-sodium chloride-butyl acetate are presented. The influence of the sulfuric acid and chloride anion concentrations on the extraction equilibria of thallium was investigated. An increase in the acidity of the aqueous phase results in steeper extraction isotherms, and the amount of thallium extracted generally increases. The influence of chloride anions on the equilibrium is more complex. It was found that the extraction equilibria is not influenced by the chloride ion concentration, provided that the Cl/Tl ratio in the aqueous phase is greater than or equal to 4. If this ratio is less than 4, the concentration of chloride anions significantly influences the extraction isotherms. The results obtained are discussed in terms of the composition of the complex in the organic phase. An apparent reaction constant equation is proposed for the prediction of the extraction equilibria.",
journal = "Separation Science and Technology",
title = "Extraction of thallium with butyl acetate",
volume = "34",
number = "5",
pages = "771-779",
url = "https://hdl.handle.net/21.15107/rcub_vinar_2245"
}

Trtić, T. M.,& Čomor, J. J.. (1999). Extraction of thallium with butyl acetate. in Separation Science and Technology, 34(5), 771-779.
https://hdl.handle.net/21.15107/rcub_vinar_2245

Trtić TM, Čomor JJ. Extraction of thallium with butyl acetate. in Separation Science and Technology. 1999;34(5):771-779.
https://hdl.handle.net/21.15107/rcub_vinar_2245 .

Trtić, Tatjana M., Čomor, Jožef J., "Extraction of thallium with butyl acetate" in Separation Science and Technology, 34, no. 5 (1999):771-779,
https://hdl.handle.net/21.15107/rcub_vinar_2245 .

TY  - JOUR
AU  - Milojković, Smiljana S.
AU  - Kostoski, Dušan
AU  - Čomor, Jožef J.
AU  - Nedeljković, Jovan
PY  - 1997
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2063
AB  - A new synthetic procedure for preparation of molecularly imprinted polymers (MIPs) was developed. The polymerization process was initiated by gamma-radiation, in the model system with (+/-)-menthol as a template molecule. The thermal stability of MIP was investigated by thermogravimetric analysis and differential scanning calorimetry, while the specific surface area was determined from Brumauer-Emmett-Teller isotherm. Adsorption properties and recognition capabilities of MIPs were examined by comparison of the adsorption isotherms of menthol and camphor (test molecule) from n-hexane. The adsorption isotherms corresponded to Langmuir type adsorption, and the difference between adsorbate-adsorbent interaction energies was clarified. (C) 1997 Elsevier Science Ltd.
T2  - Polymer
T1  - Radiation induced synthesis of molecularly imprinted polymers
VL  - 38
IS  - 11
SP  - 2853
EP  - 2855
DO  - 10.1016/S0032-3861(97)85624-8
ER  - 

@article{
author = "Milojković, Smiljana S. and Kostoski, Dušan and Čomor, Jožef J. and Nedeljković, Jovan",
year = "1997",
abstract = "A new synthetic procedure for preparation of molecularly imprinted polymers (MIPs) was developed. The polymerization process was initiated by gamma-radiation, in the model system with (+/-)-menthol as a template molecule. The thermal stability of MIP was investigated by thermogravimetric analysis and differential scanning calorimetry, while the specific surface area was determined from Brumauer-Emmett-Teller isotherm. Adsorption properties and recognition capabilities of MIPs were examined by comparison of the adsorption isotherms of menthol and camphor (test molecule) from n-hexane. The adsorption isotherms corresponded to Langmuir type adsorption, and the difference between adsorbate-adsorbent interaction energies was clarified. (C) 1997 Elsevier Science Ltd.",
journal = "Polymer",
title = "Radiation induced synthesis of molecularly imprinted polymers",
volume = "38",
number = "11",
pages = "2853-2855",
doi = "10.1016/S0032-3861(97)85624-8"
}

Milojković, S. S., Kostoski, D., Čomor, J. J.,& Nedeljković, J.. (1997). Radiation induced synthesis of molecularly imprinted polymers. in Polymer, 38(11), 2853-2855.
https://doi.org/10.1016/S0032-3861(97)85624-8

Milojković SS, Kostoski D, Čomor JJ, Nedeljković J. Radiation induced synthesis of molecularly imprinted polymers. in Polymer. 1997;38(11):2853-2855.
doi:10.1016/S0032-3861(97)85624-8 .

Milojković, Smiljana S., Kostoski, Dušan, Čomor, Jožef J., Nedeljković, Jovan, "Radiation induced synthesis of molecularly imprinted polymers" in Polymer, 38, no. 11 (1997):2853-2855,
https://doi.org/10.1016/S0032-3861(97)85624-8 . .