Paunović, Verica G.

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  • Paunović, Verica G. (13)

Author's Bibliography

Graphene quantum dots inhibit T cell-mediated neuroinflammation in rats

Tošić, Jelena; Stanojević, Željka; Vidičević, Sašenka; Isaković, Aleksandra J.; Ćirić, Darko; Martinović, Tamara; Kravić-Stevović, Tamara K.; Bumbaširević, Vladimir Ž.; Paunović, Verica G.; Jovanović, Svetlana P.; Todorović-Marković, Biljana; Marković, Zoran M.; Danko, Martin; Mičušik, Matej; Spitalsky, Zdenko; Trajković, Vladimir S.

(2019)

TY  - JOUR
AU  - Tošić, Jelena
AU  - Stanojević, Željka
AU  - Vidičević, Sašenka
AU  - Isaković, Aleksandra J.
AU  - Ćirić, Darko
AU  - Martinović, Tamara
AU  - Kravić-Stevović, Tamara K.
AU  - Bumbaširević, Vladimir Ž.
AU  - Paunović, Verica G.
AU  - Jovanović, Svetlana P.
AU  - Todorović-Marković, Biljana
AU  - Marković, Zoran M.
AU  - Danko, Martin
AU  - Mičušik, Matej
AU  - Spitalsky, Zdenko
AU  - Trajković, Vladimir S.
PY  - 2019
UR  - https://linkinghub.elsevier.com/retrieve/pii/S0028390818308621
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/8015
AB  - We investigated the therapeutic capacity of nano-sized graphene sheets, called graphene quantum dots (GQD), in experimental autoimmune encephalomyelitis (EAE), an animal model of immune-mediated central nervous system (CNS) damage. Intraperitoneally administered GQD (10 mg/kg/day) accumulated in the lymph node and CNS cells of Dark Agouti rats in which EAE was induced by immunization with spinal cord homogenate in complete Freund's adjuvant. GQD significantly reduced clinical signs of EAE when applied throughout the course of the disease (day 0–32), while the protection was less pronounced if the treatment was limited to the induction (day 0–7 post-immunization) or effector (from day 8 onwards) phase of the disease. GQD treatment diminished immune infiltration, demyelination, axonal damage, and apoptotic death in the CNS of EAE animals. GQD also reduced the numbers of interferon-γ-expressing T helper (Th)1 cells, as well as the expression of Th1 transcription factor T-bet and proinflammatory cytokines tumor necrosis factor, interleukin-1, and granulocyte-macrophage colony-stimulating factor in the lymph nodes and CNS immune infitrates. The protective effect of GQD in EAE was associated with the activation of p38 and p42/44 mitogen-activated protein kinases (MAPK) and Akt in the lymph nodes and/or CNS. Finally, GQD protected oligodendrocytes and neurons from T cell-mediated damage in the in vitro conditions. Collectively, these data demonstrate the ability of GQD to gain access to both immune and CNS cells during neuroinflammation, and to alleviate immune-mediated CNS damage by modulating MAPK/Akt signaling and encephalitogenic Th1 immune response. © 2018 Elsevier Ltd
T2  - Neuropharmacology
T1  - Graphene quantum dots inhibit T cell-mediated neuroinflammation in rats
VL  - 146
SP  - 95
EP  - 108
DO  - 10.1016/j.neuropharm.2018.11.030
ER  - 
@article{
author = "Tošić, Jelena and Stanojević, Željka and Vidičević, Sašenka and Isaković, Aleksandra J. and Ćirić, Darko and Martinović, Tamara and Kravić-Stevović, Tamara K. and Bumbaširević, Vladimir Ž. and Paunović, Verica G. and Jovanović, Svetlana P. and Todorović-Marković, Biljana and Marković, Zoran M. and Danko, Martin and Mičušik, Matej and Spitalsky, Zdenko and Trajković, Vladimir S.",
year = "2019",
abstract = "We investigated the therapeutic capacity of nano-sized graphene sheets, called graphene quantum dots (GQD), in experimental autoimmune encephalomyelitis (EAE), an animal model of immune-mediated central nervous system (CNS) damage. Intraperitoneally administered GQD (10 mg/kg/day) accumulated in the lymph node and CNS cells of Dark Agouti rats in which EAE was induced by immunization with spinal cord homogenate in complete Freund's adjuvant. GQD significantly reduced clinical signs of EAE when applied throughout the course of the disease (day 0–32), while the protection was less pronounced if the treatment was limited to the induction (day 0–7 post-immunization) or effector (from day 8 onwards) phase of the disease. GQD treatment diminished immune infiltration, demyelination, axonal damage, and apoptotic death in the CNS of EAE animals. GQD also reduced the numbers of interferon-γ-expressing T helper (Th)1 cells, as well as the expression of Th1 transcription factor T-bet and proinflammatory cytokines tumor necrosis factor, interleukin-1, and granulocyte-macrophage colony-stimulating factor in the lymph nodes and CNS immune infitrates. The protective effect of GQD in EAE was associated with the activation of p38 and p42/44 mitogen-activated protein kinases (MAPK) and Akt in the lymph nodes and/or CNS. Finally, GQD protected oligodendrocytes and neurons from T cell-mediated damage in the in vitro conditions. Collectively, these data demonstrate the ability of GQD to gain access to both immune and CNS cells during neuroinflammation, and to alleviate immune-mediated CNS damage by modulating MAPK/Akt signaling and encephalitogenic Th1 immune response. © 2018 Elsevier Ltd",
journal = "Neuropharmacology",
title = "Graphene quantum dots inhibit T cell-mediated neuroinflammation in rats",
volume = "146",
pages = "95-108",
doi = "10.1016/j.neuropharm.2018.11.030"
}
Tošić, J., Stanojević, Ž., Vidičević, S., Isaković, A. J., Ćirić, D., Martinović, T., Kravić-Stevović, T. K., Bumbaširević, V. Ž., Paunović, V. G., Jovanović, S. P., Todorović-Marković, B., Marković, Z. M., Danko, M., Mičušik, M., Spitalsky, Z.,& Trajković, V. S.. (2019). Graphene quantum dots inhibit T cell-mediated neuroinflammation in rats. in Neuropharmacology, 146, 95-108.
https://doi.org/10.1016/j.neuropharm.2018.11.030
Tošić J, Stanojević Ž, Vidičević S, Isaković AJ, Ćirić D, Martinović T, Kravić-Stevović TK, Bumbaširević VŽ, Paunović VG, Jovanović SP, Todorović-Marković B, Marković ZM, Danko M, Mičušik M, Spitalsky Z, Trajković VS. Graphene quantum dots inhibit T cell-mediated neuroinflammation in rats. in Neuropharmacology. 2019;146:95-108.
doi:10.1016/j.neuropharm.2018.11.030 .
Tošić, Jelena, Stanojević, Željka, Vidičević, Sašenka, Isaković, Aleksandra J., Ćirić, Darko, Martinović, Tamara, Kravić-Stevović, Tamara K., Bumbaširević, Vladimir Ž., Paunović, Verica G., Jovanović, Svetlana P., Todorović-Marković, Biljana, Marković, Zoran M., Danko, Martin, Mičušik, Matej, Spitalsky, Zdenko, Trajković, Vladimir S., "Graphene quantum dots inhibit T cell-mediated neuroinflammation in rats" in Neuropharmacology, 146 (2019):95-108,
https://doi.org/10.1016/j.neuropharm.2018.11.030 . .
12
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11

Transmission Electron Microscopy in Evaluation of Curcumin Nanoparticles Cellular Uptake

Kravić-Stevović, Tamara K.; Martinović, Tamara; Ćirić, Darko; Paunović, Verica G.; Ristić, Biljana; Marković, Zoran M.; Todorović-Marković, Biljana; Kosić, Milica; Prekodravac, Jovana; Micusik, Matej; Spitalsky, Zdeno; Trajković, Vladimir S.; Harhaji-Trajković, Ljubica M.; Bumbaširević, Vladimir Ž.

(Belgrade : Serbian Academy of Sciences and Arts, 2018)

TY  - CONF
AU  - Kravić-Stevović, Tamara K.
AU  - Martinović, Tamara
AU  - Ćirić, Darko
AU  - Paunović, Verica G.
AU  - Ristić, Biljana
AU  - Marković, Zoran M.
AU  - Todorović-Marković, Biljana
AU  - Kosić, Milica
AU  - Prekodravac, Jovana
AU  - Micusik, Matej
AU  - Spitalsky, Zdeno
AU  - Trajković, Vladimir S.
AU  - Harhaji-Trajković, Ljubica M.
AU  - Bumbaširević, Vladimir Ž.
PY  - 2018
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/8740
PB  - Belgrade : Serbian Academy of Sciences and Arts
C3  - Program and Book of Abstracts / First International Conference on Electron Microscopy of Nanostructures ELMINA 2018, August 27-29, 2018, Belgrade, Serbia
T1  - Transmission Electron Microscopy in Evaluation of Curcumin Nanoparticles Cellular Uptake
SP  - 266
EP  - 268
ER  - 
@conference{
author = "Kravić-Stevović, Tamara K. and Martinović, Tamara and Ćirić, Darko and Paunović, Verica G. and Ristić, Biljana and Marković, Zoran M. and Todorović-Marković, Biljana and Kosić, Milica and Prekodravac, Jovana and Micusik, Matej and Spitalsky, Zdeno and Trajković, Vladimir S. and Harhaji-Trajković, Ljubica M. and Bumbaširević, Vladimir Ž.",
year = "2018",
publisher = "Belgrade : Serbian Academy of Sciences and Arts",
journal = "Program and Book of Abstracts / First International Conference on Electron Microscopy of Nanostructures ELMINA 2018, August 27-29, 2018, Belgrade, Serbia",
title = "Transmission Electron Microscopy in Evaluation of Curcumin Nanoparticles Cellular Uptake",
pages = "266-268"
}
Kravić-Stevović, T. K., Martinović, T., Ćirić, D., Paunović, V. G., Ristić, B., Marković, Z. M., Todorović-Marković, B., Kosić, M., Prekodravac, J., Micusik, M., Spitalsky, Z., Trajković, V. S., Harhaji-Trajković, L. M.,& Bumbaširević, V. Ž.. (2018). Transmission Electron Microscopy in Evaluation of Curcumin Nanoparticles Cellular Uptake. in Program and Book of Abstracts / First International Conference on Electron Microscopy of Nanostructures ELMINA 2018, August 27-29, 2018, Belgrade, Serbia
Belgrade : Serbian Academy of Sciences and Arts., 266-268.
Kravić-Stevović TK, Martinović T, Ćirić D, Paunović VG, Ristić B, Marković ZM, Todorović-Marković B, Kosić M, Prekodravac J, Micusik M, Spitalsky Z, Trajković VS, Harhaji-Trajković LM, Bumbaširević VŽ. Transmission Electron Microscopy in Evaluation of Curcumin Nanoparticles Cellular Uptake. in Program and Book of Abstracts / First International Conference on Electron Microscopy of Nanostructures ELMINA 2018, August 27-29, 2018, Belgrade, Serbia. 2018;:266-268..
Kravić-Stevović, Tamara K., Martinović, Tamara, Ćirić, Darko, Paunović, Verica G., Ristić, Biljana, Marković, Zoran M., Todorović-Marković, Biljana, Kosić, Milica, Prekodravac, Jovana, Micusik, Matej, Spitalsky, Zdeno, Trajković, Vladimir S., Harhaji-Trajković, Ljubica M., Bumbaširević, Vladimir Ž., "Transmission Electron Microscopy in Evaluation of Curcumin Nanoparticles Cellular Uptake" in Program and Book of Abstracts / First International Conference on Electron Microscopy of Nanostructures ELMINA 2018, August 27-29, 2018, Belgrade, Serbia (2018):266-268.

Ultrastructural Analysis of Large Graphene Quantum Dots Internalization in Hepatocytes

Ćirić, Darko; Martinović, Tamara; Kravić-Stevović, Tamara K.; Volarević, Vladislav; Paunović, Verica G.; Marković, Zoran M.; Marković-Simović, Bojana; Misirkić-Marjanović, Maja; Todorović-Marković, Biljana; Bojić, Sanja; Vučićević, Ljubica; Jovanović, Svetlana P.; Arsenijević, Nebojša N.; Holclajtner-Antunović, Ivanka D.; Milosavljević, Momir; Dramićanin, Miroslav; Lukić, Miodrag L.; Trajković, Vladimir S.; Bumbaširević, Vladimir Ž.

(Belgrade : Serbian Academy of Sciences and Arts, 2018)

TY  - CONF
AU  - Ćirić, Darko
AU  - Martinović, Tamara
AU  - Kravić-Stevović, Tamara K.
AU  - Volarević, Vladislav
AU  - Paunović, Verica G.
AU  - Marković, Zoran M.
AU  - Marković-Simović, Bojana
AU  - Misirkić-Marjanović, Maja
AU  - Todorović-Marković, Biljana
AU  - Bojić, Sanja
AU  - Vučićević, Ljubica
AU  - Jovanović, Svetlana P.
AU  - Arsenijević, Nebojša N.
AU  - Holclajtner-Antunović, Ivanka D.
AU  - Milosavljević, Momir
AU  - Dramićanin, Miroslav
AU  - Lukić, Miodrag L.
AU  - Trajković, Vladimir S.
AU  - Bumbaširević, Vladimir Ž.
PY  - 2018
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/8741
PB  - Belgrade : Serbian Academy of Sciences and Arts
C3  - Program and Book of Abstracts / First International Conference on Electron Microscopy of Nanostructures ELMINA 2018, August 27-29, 2018, Belgrade, Serbia
T1  - Ultrastructural Analysis of Large Graphene Quantum Dots Internalization in Hepatocytes
SP  - 272
EP  - 274
ER  - 
@conference{
author = "Ćirić, Darko and Martinović, Tamara and Kravić-Stevović, Tamara K. and Volarević, Vladislav and Paunović, Verica G. and Marković, Zoran M. and Marković-Simović, Bojana and Misirkić-Marjanović, Maja and Todorović-Marković, Biljana and Bojić, Sanja and Vučićević, Ljubica and Jovanović, Svetlana P. and Arsenijević, Nebojša N. and Holclajtner-Antunović, Ivanka D. and Milosavljević, Momir and Dramićanin, Miroslav and Lukić, Miodrag L. and Trajković, Vladimir S. and Bumbaširević, Vladimir Ž.",
year = "2018",
publisher = "Belgrade : Serbian Academy of Sciences and Arts",
journal = "Program and Book of Abstracts / First International Conference on Electron Microscopy of Nanostructures ELMINA 2018, August 27-29, 2018, Belgrade, Serbia",
title = "Ultrastructural Analysis of Large Graphene Quantum Dots Internalization in Hepatocytes",
pages = "272-274"
}
Ćirić, D., Martinović, T., Kravić-Stevović, T. K., Volarević, V., Paunović, V. G., Marković, Z. M., Marković-Simović, B., Misirkić-Marjanović, M., Todorović-Marković, B., Bojić, S., Vučićević, L., Jovanović, S. P., Arsenijević, N. N., Holclajtner-Antunović, I. D., Milosavljević, M., Dramićanin, M., Lukić, M. L., Trajković, V. S.,& Bumbaširević, V. Ž.. (2018). Ultrastructural Analysis of Large Graphene Quantum Dots Internalization in Hepatocytes. in Program and Book of Abstracts / First International Conference on Electron Microscopy of Nanostructures ELMINA 2018, August 27-29, 2018, Belgrade, Serbia
Belgrade : Serbian Academy of Sciences and Arts., 272-274.
Ćirić D, Martinović T, Kravić-Stevović TK, Volarević V, Paunović VG, Marković ZM, Marković-Simović B, Misirkić-Marjanović M, Todorović-Marković B, Bojić S, Vučićević L, Jovanović SP, Arsenijević NN, Holclajtner-Antunović ID, Milosavljević M, Dramićanin M, Lukić ML, Trajković VS, Bumbaširević VŽ. Ultrastructural Analysis of Large Graphene Quantum Dots Internalization in Hepatocytes. in Program and Book of Abstracts / First International Conference on Electron Microscopy of Nanostructures ELMINA 2018, August 27-29, 2018, Belgrade, Serbia. 2018;:272-274..
Ćirić, Darko, Martinović, Tamara, Kravić-Stevović, Tamara K., Volarević, Vladislav, Paunović, Verica G., Marković, Zoran M., Marković-Simović, Bojana, Misirkić-Marjanović, Maja, Todorović-Marković, Biljana, Bojić, Sanja, Vučićević, Ljubica, Jovanović, Svetlana P., Arsenijević, Nebojša N., Holclajtner-Antunović, Ivanka D., Milosavljević, Momir, Dramićanin, Miroslav, Lukić, Miodrag L., Trajković, Vladimir S., Bumbaširević, Vladimir Ž., "Ultrastructural Analysis of Large Graphene Quantum Dots Internalization in Hepatocytes" in Program and Book of Abstracts / First International Conference on Electron Microscopy of Nanostructures ELMINA 2018, August 27-29, 2018, Belgrade, Serbia (2018):272-274.

Ultrasmall iron oxide nanoparticles: Magnetic and NMR relaxometric properties

Babić-Stojić, Branka S.; Jokanović, Vukoman R.; Milivojević, Dušan; Pozek, Miroslav; Jaglicic, Zvonko; Makovec, Darko; Jović Orsini, Nataša; Marković, Mirjana; Arsikin, Katarina M.; Paunović, Verica G.

(2018)

TY  - JOUR
AU  - Babić-Stojić, Branka S.
AU  - Jokanović, Vukoman R.
AU  - Milivojević, Dušan
AU  - Pozek, Miroslav
AU  - Jaglicic, Zvonko
AU  - Makovec, Darko
AU  - Jović Orsini, Nataša
AU  - Marković, Mirjana
AU  - Arsikin, Katarina M.
AU  - Paunović, Verica G.
PY  - 2018
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/1889
AB  - Ultrasmall iron oxide (USPIO) nanoparticles, with diameter mostly less than 3 nm dispersed in an organic carrier fluid were synthesized by polyol route. The evolution of ZFC-FC magnetization curves with temperature, as well as the shift of the ac susceptibility peaks upon changing the frequency, reveal that the nanoparticles in the fluid are non-interacting and superparamagnetic with the blocking temperature T-B similar to 10 K. The Mossbauer spectra analysis proposed the core/shell structure of the nanoparticles consisting of stoichiometric gamma-Fe2O3 core and non-stoichiometric shell. The nanoparticle surface layer has a great influence on their properties which is principally manifested in significant reduction of the magnetization and in a large increase in magnetic anisotropy. Magnetic moments do not saturate in fields up to 5 T, even at the lowest measured temperature, T = 5 K. The average magnetic particle diameter is changed from 1.3 to 1.8 nm with increasing magnetic field from 0 to 5 T which is noticeably smaller than the particle sizes measured by TEM. The estimated effective magnetic anisotropy constant value, K-eff = 2 x 10(5) J/m(3), is two orders of magnitude higher than in the bulk maghemite. Measurements of the longitudinal and transverse NMR relaxivity parameters on water diluted nanoparticle dispersions at 1.5 T gave the values r(1) = 0.028 mmol(-1) s(-1), r(2) = 0.050 mmol(-1) s(-1) and their ratio r(2)/r(1) = 1.8. Continuous increase of the T-1-weighted MRI signal intensity with increasing Fe concentration in the nanoparticle dispersions was observed which makes this ferrofluid to behave as a positive T-1 contrast agent. (C) 2017 Elsevier B.V. All rights reserved.
T2  - Current Applied Physics
T1  - Ultrasmall iron oxide nanoparticles: Magnetic and NMR relaxometric properties
VL  - 18
IS  - 2
SP  - 141
EP  - 149
DO  - 10.1016/j.cap.2017.11.017
ER  - 
@article{
author = "Babić-Stojić, Branka S. and Jokanović, Vukoman R. and Milivojević, Dušan and Pozek, Miroslav and Jaglicic, Zvonko and Makovec, Darko and Jović Orsini, Nataša and Marković, Mirjana and Arsikin, Katarina M. and Paunović, Verica G.",
year = "2018",
abstract = "Ultrasmall iron oxide (USPIO) nanoparticles, with diameter mostly less than 3 nm dispersed in an organic carrier fluid were synthesized by polyol route. The evolution of ZFC-FC magnetization curves with temperature, as well as the shift of the ac susceptibility peaks upon changing the frequency, reveal that the nanoparticles in the fluid are non-interacting and superparamagnetic with the blocking temperature T-B similar to 10 K. The Mossbauer spectra analysis proposed the core/shell structure of the nanoparticles consisting of stoichiometric gamma-Fe2O3 core and non-stoichiometric shell. The nanoparticle surface layer has a great influence on their properties which is principally manifested in significant reduction of the magnetization and in a large increase in magnetic anisotropy. Magnetic moments do not saturate in fields up to 5 T, even at the lowest measured temperature, T = 5 K. The average magnetic particle diameter is changed from 1.3 to 1.8 nm with increasing magnetic field from 0 to 5 T which is noticeably smaller than the particle sizes measured by TEM. The estimated effective magnetic anisotropy constant value, K-eff = 2 x 10(5) J/m(3), is two orders of magnitude higher than in the bulk maghemite. Measurements of the longitudinal and transverse NMR relaxivity parameters on water diluted nanoparticle dispersions at 1.5 T gave the values r(1) = 0.028 mmol(-1) s(-1), r(2) = 0.050 mmol(-1) s(-1) and their ratio r(2)/r(1) = 1.8. Continuous increase of the T-1-weighted MRI signal intensity with increasing Fe concentration in the nanoparticle dispersions was observed which makes this ferrofluid to behave as a positive T-1 contrast agent. (C) 2017 Elsevier B.V. All rights reserved.",
journal = "Current Applied Physics",
title = "Ultrasmall iron oxide nanoparticles: Magnetic and NMR relaxometric properties",
volume = "18",
number = "2",
pages = "141-149",
doi = "10.1016/j.cap.2017.11.017"
}
Babić-Stojić, B. S., Jokanović, V. R., Milivojević, D., Pozek, M., Jaglicic, Z., Makovec, D., Jović Orsini, N., Marković, M., Arsikin, K. M.,& Paunović, V. G.. (2018). Ultrasmall iron oxide nanoparticles: Magnetic and NMR relaxometric properties. in Current Applied Physics, 18(2), 141-149.
https://doi.org/10.1016/j.cap.2017.11.017
Babić-Stojić BS, Jokanović VR, Milivojević D, Pozek M, Jaglicic Z, Makovec D, Jović Orsini N, Marković M, Arsikin KM, Paunović VG. Ultrasmall iron oxide nanoparticles: Magnetic and NMR relaxometric properties. in Current Applied Physics. 2018;18(2):141-149.
doi:10.1016/j.cap.2017.11.017 .
Babić-Stojić, Branka S., Jokanović, Vukoman R., Milivojević, Dušan, Pozek, Miroslav, Jaglicic, Zvonko, Makovec, Darko, Jović Orsini, Nataša, Marković, Mirjana, Arsikin, Katarina M., Paunović, Verica G., "Ultrasmall iron oxide nanoparticles: Magnetic and NMR relaxometric properties" in Current Applied Physics, 18, no. 2 (2018):141-149,
https://doi.org/10.1016/j.cap.2017.11.017 . .
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Graphene quantum dots show protective effect on a model of experimental autoimmune encephalomyelitis

Tošić, Jelena; Vidičević, Sašenka; Stanojević, Željka; Paunović, Verica G.; Petricevic, S.; Martinović, Tamara; Kravić-Stevović, Tamara K.; Ćirić, Darko; Marković, Zoran M.; Isaković, Aleksandra J.; Trajković, Vladimir S.

(2016)

TY  - CONF
AU  - Tošić, Jelena
AU  - Vidičević, Sašenka
AU  - Stanojević, Željka
AU  - Paunović, Verica G.
AU  - Petricevic, S.
AU  - Martinović, Tamara
AU  - Kravić-Stevović, Tamara K.
AU  - Ćirić, Darko
AU  - Marković, Zoran M.
AU  - Isaković, Aleksandra J.
AU  - Trajković, Vladimir S.
PY  - 2016
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/7160
C3  - European Neuropsychopharmacology
T1  - Graphene quantum dots show protective effect on a model of experimental autoimmune encephalomyelitis
VL  - 26
SP  - S211
EP  - S212
DO  - 10.1016/S0924-977X(16)31060-4
ER  - 
@conference{
author = "Tošić, Jelena and Vidičević, Sašenka and Stanojević, Željka and Paunović, Verica G. and Petricevic, S. and Martinović, Tamara and Kravić-Stevović, Tamara K. and Ćirić, Darko and Marković, Zoran M. and Isaković, Aleksandra J. and Trajković, Vladimir S.",
year = "2016",
journal = "European Neuropsychopharmacology",
title = "Graphene quantum dots show protective effect on a model of experimental autoimmune encephalomyelitis",
volume = "26",
pages = "S211-S212",
doi = "10.1016/S0924-977X(16)31060-4"
}
Tošić, J., Vidičević, S., Stanojević, Ž., Paunović, V. G., Petricevic, S., Martinović, T., Kravić-Stevović, T. K., Ćirić, D., Marković, Z. M., Isaković, A. J.,& Trajković, V. S.. (2016). Graphene quantum dots show protective effect on a model of experimental autoimmune encephalomyelitis. in European Neuropsychopharmacology, 26, S211-S212.
https://doi.org/10.1016/S0924-977X(16)31060-4
Tošić J, Vidičević S, Stanojević Ž, Paunović VG, Petricevic S, Martinović T, Kravić-Stevović TK, Ćirić D, Marković ZM, Isaković AJ, Trajković VS. Graphene quantum dots show protective effect on a model of experimental autoimmune encephalomyelitis. in European Neuropsychopharmacology. 2016;26:S211-S212.
doi:10.1016/S0924-977X(16)31060-4 .
Tošić, Jelena, Vidičević, Sašenka, Stanojević, Željka, Paunović, Verica G., Petricevic, S., Martinović, Tamara, Kravić-Stevović, Tamara K., Ćirić, Darko, Marković, Zoran M., Isaković, Aleksandra J., Trajković, Vladimir S., "Graphene quantum dots show protective effect on a model of experimental autoimmune encephalomyelitis" in European Neuropsychopharmacology, 26 (2016):S211-S212,
https://doi.org/10.1016/S0924-977X(16)31060-4 . .
2
1

c-Jun N-terminal kinase-dependent apoptotic photocytotoxicity of solvent exchange-prepared curcumin nanoparticles

Paunović, Verica G.; Ristić, Biljana; Marković, Zoran M.; Todorović-Marković, Biljana; Kosić, Milica; Prekodravac, Jovana; Kravić-Stevović, Tamara K.; Martinović, Tamara; Mičušik, Matej; Špitalsky, Zdenko; Trajković, Vladimir S.; Harhaji-Trajković, Ljubica M.

(Springer, 2016)

TY  - JOUR
AU  - Paunović, Verica G.
AU  - Ristić, Biljana
AU  - Marković, Zoran M.
AU  - Todorović-Marković, Biljana
AU  - Kosić, Milica
AU  - Prekodravac, Jovana
AU  - Kravić-Stevović, Tamara K.
AU  - Martinović, Tamara
AU  - Mičušik, Matej
AU  - Špitalsky, Zdenko
AU  - Trajković, Vladimir S.
AU  - Harhaji-Trajković, Ljubica M.
PY  - 2016
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/1084
AB  - Indian spice curcumin is known for its anticancer properties, but the anticancer mechanisms of nanoparticulate curcumin have not been completely elucidated. We here investigated the in vitro anticancer effect of blue light (470 nm, 1 W)-irradiated curcumin nanoparticles prepared by tetrahydrofuran/water solvent exchange, using U251 glioma, B16 melanoma, and H460 lung cancer cells as targets. The size of curcumin nanocrystals was approximately 250 nm, while photoexcitation induced their oxidation and partial agglomeration. Although cell membrane in the absence of light was almost impermeable to curcumin nanoparticles, photoexcitation stimulated their internalization. While irradiation with blue light (1-8 min) or nanocurcumin (1.25-10 mu g/ml) alone was only marginally toxic to tumor cells, photoexcited nanocurcumin displayed a significant cytotoxicity depending both on the irradiation time and nanocurcumin concentration. Photoexcited nanocurcumin induced phosphorylation of cJun N-terminal kinase (JNK), mitochondrial depolarization, caspase-3 activation, and cleavage of poly (ADP-ribose) polymerase, indicating apoptotic cell death. Accordingly, pharmacologial inhibition of JNK and caspase activity rescued cancer cells from photoexcited nanocurcumin. On the other hand, antioxidant treatment did not reduce photocytotoxicity of nanocurcumin, arguing against the involvement of oxidative stress. By demonstrating the ability of photoexcited nanocurcumin to induce oxidative-stress independent, JNK-and caspase-dependent apoptosis, our results support its further investigation in cancer therapy.
PB  - Springer
T2  - Biomedical Microdevices
T1  - c-Jun N-terminal kinase-dependent apoptotic photocytotoxicity of solvent exchange-prepared curcumin nanoparticles
VL  - 18
IS  - 2
DO  - 10.1007/s10544-016-0062-2
ER  - 
@article{
author = "Paunović, Verica G. and Ristić, Biljana and Marković, Zoran M. and Todorović-Marković, Biljana and Kosić, Milica and Prekodravac, Jovana and Kravić-Stevović, Tamara K. and Martinović, Tamara and Mičušik, Matej and Špitalsky, Zdenko and Trajković, Vladimir S. and Harhaji-Trajković, Ljubica M.",
year = "2016",
abstract = "Indian spice curcumin is known for its anticancer properties, but the anticancer mechanisms of nanoparticulate curcumin have not been completely elucidated. We here investigated the in vitro anticancer effect of blue light (470 nm, 1 W)-irradiated curcumin nanoparticles prepared by tetrahydrofuran/water solvent exchange, using U251 glioma, B16 melanoma, and H460 lung cancer cells as targets. The size of curcumin nanocrystals was approximately 250 nm, while photoexcitation induced their oxidation and partial agglomeration. Although cell membrane in the absence of light was almost impermeable to curcumin nanoparticles, photoexcitation stimulated their internalization. While irradiation with blue light (1-8 min) or nanocurcumin (1.25-10 mu g/ml) alone was only marginally toxic to tumor cells, photoexcited nanocurcumin displayed a significant cytotoxicity depending both on the irradiation time and nanocurcumin concentration. Photoexcited nanocurcumin induced phosphorylation of cJun N-terminal kinase (JNK), mitochondrial depolarization, caspase-3 activation, and cleavage of poly (ADP-ribose) polymerase, indicating apoptotic cell death. Accordingly, pharmacologial inhibition of JNK and caspase activity rescued cancer cells from photoexcited nanocurcumin. On the other hand, antioxidant treatment did not reduce photocytotoxicity of nanocurcumin, arguing against the involvement of oxidative stress. By demonstrating the ability of photoexcited nanocurcumin to induce oxidative-stress independent, JNK-and caspase-dependent apoptosis, our results support its further investigation in cancer therapy.",
publisher = "Springer",
journal = "Biomedical Microdevices",
title = "c-Jun N-terminal kinase-dependent apoptotic photocytotoxicity of solvent exchange-prepared curcumin nanoparticles",
volume = "18",
number = "2",
doi = "10.1007/s10544-016-0062-2"
}
Paunović, V. G., Ristić, B., Marković, Z. M., Todorović-Marković, B., Kosić, M., Prekodravac, J., Kravić-Stevović, T. K., Martinović, T., Mičušik, M., Špitalsky, Z., Trajković, V. S.,& Harhaji-Trajković, L. M.. (2016). c-Jun N-terminal kinase-dependent apoptotic photocytotoxicity of solvent exchange-prepared curcumin nanoparticles. in Biomedical Microdevices
Springer., 18(2).
https://doi.org/10.1007/s10544-016-0062-2
Paunović VG, Ristić B, Marković ZM, Todorović-Marković B, Kosić M, Prekodravac J, Kravić-Stevović TK, Martinović T, Mičušik M, Špitalsky Z, Trajković VS, Harhaji-Trajković LM. c-Jun N-terminal kinase-dependent apoptotic photocytotoxicity of solvent exchange-prepared curcumin nanoparticles. in Biomedical Microdevices. 2016;18(2).
doi:10.1007/s10544-016-0062-2 .
Paunović, Verica G., Ristić, Biljana, Marković, Zoran M., Todorović-Marković, Biljana, Kosić, Milica, Prekodravac, Jovana, Kravić-Stevović, Tamara K., Martinović, Tamara, Mičušik, Matej, Špitalsky, Zdenko, Trajković, Vladimir S., Harhaji-Trajković, Ljubica M., "c-Jun N-terminal kinase-dependent apoptotic photocytotoxicity of solvent exchange-prepared curcumin nanoparticles" in Biomedical Microdevices, 18, no. 2 (2016),
https://doi.org/10.1007/s10544-016-0062-2 . .
1
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10
10

Gd2O3 nanoparticles stabilized by hydrothermally modified dextrose for positive contrast magnetic resonance imaging

Babić-Stojić, Branka S.; Jokanović, Vukoman R.; Milivojević, Dušan; Pozek, Miroslav; Jaglicic, Zvonko; Makovec, Darko; Arsikin, Katarina M.; Paunović, Verica G.

(Elsevier, 2016)

TY  - JOUR
AU  - Babić-Stojić, Branka S.
AU  - Jokanović, Vukoman R.
AU  - Milivojević, Dušan
AU  - Pozek, Miroslav
AU  - Jaglicic, Zvonko
AU  - Makovec, Darko
AU  - Arsikin, Katarina M.
AU  - Paunović, Verica G.
PY  - 2016
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/857
AB  - w Gd2O3 nanoparticles of a few nm in size and their agglomerates dispersed in dextrose derived polymer template were synthesized by hydrothermal treatment. The produced nanosized material was investigated by TEM, FTIR spectroscopy, SQUID measurements and NMR relaxometry. Biological evaluation of this material was done by crystal violet and MTT assays to determine the cell viability. Longitudinal and transverse NMR relaxivities of water diluted Gd2O3 nanoparticle dispersions measured at the magnetic field of 1.5 T, estimated to be r(1)(Gd2O3)=9.6 s(-1) mM(-1) in the Gd concentration range 0.1-30 mM and r(2)(Gd2O3)=17.7 s(-1) mM(-1) in the lower concentration range 0.1-0.8 mM, are significantly higher than the corresponding relaxivities measured for the standard contrast agent r1 (Gd-DTPA)=4.1 s(-1) mM(-1) and r(2)(Gd-DTPA)= 5.1 s(-1) mM(-1). The ratio of the two relaxivities for Gd2O3 nanoparticles r(2)/r(1) = 1.8 is suitable for T-1-weighted imaging. Good MRI signal intensities of the water diluted Gd2O3 nanoparticle dispersions were recorded at lower Gd concentrations 0.2-0.8 mM. The Gd2O3 samples did not exert any significant cytotoxic effects at Gd concentrations of 0.2 mM and below. These properties of the produced Gd2O3 nanoparticles in hydrothermally modified dextrose make them promising for potential application in MRI for the design of a positive MRI contrast agent. (C) 2015 Elsevier B.V. All rights reserved.
PB  - Elsevier
T2  - Journal of Magnetism and Magnetic Materials
T1  - Gd2O3 nanoparticles stabilized by hydrothermally modified dextrose for positive contrast magnetic resonance imaging
VL  - 403
SP  - 118
EP  - 126
DO  - 10.1016/j.jmmm.2015.11.075
ER  - 
@article{
author = "Babić-Stojić, Branka S. and Jokanović, Vukoman R. and Milivojević, Dušan and Pozek, Miroslav and Jaglicic, Zvonko and Makovec, Darko and Arsikin, Katarina M. and Paunović, Verica G.",
year = "2016",
abstract = "w Gd2O3 nanoparticles of a few nm in size and their agglomerates dispersed in dextrose derived polymer template were synthesized by hydrothermal treatment. The produced nanosized material was investigated by TEM, FTIR spectroscopy, SQUID measurements and NMR relaxometry. Biological evaluation of this material was done by crystal violet and MTT assays to determine the cell viability. Longitudinal and transverse NMR relaxivities of water diluted Gd2O3 nanoparticle dispersions measured at the magnetic field of 1.5 T, estimated to be r(1)(Gd2O3)=9.6 s(-1) mM(-1) in the Gd concentration range 0.1-30 mM and r(2)(Gd2O3)=17.7 s(-1) mM(-1) in the lower concentration range 0.1-0.8 mM, are significantly higher than the corresponding relaxivities measured for the standard contrast agent r1 (Gd-DTPA)=4.1 s(-1) mM(-1) and r(2)(Gd-DTPA)= 5.1 s(-1) mM(-1). The ratio of the two relaxivities for Gd2O3 nanoparticles r(2)/r(1) = 1.8 is suitable for T-1-weighted imaging. Good MRI signal intensities of the water diluted Gd2O3 nanoparticle dispersions were recorded at lower Gd concentrations 0.2-0.8 mM. The Gd2O3 samples did not exert any significant cytotoxic effects at Gd concentrations of 0.2 mM and below. These properties of the produced Gd2O3 nanoparticles in hydrothermally modified dextrose make them promising for potential application in MRI for the design of a positive MRI contrast agent. (C) 2015 Elsevier B.V. All rights reserved.",
publisher = "Elsevier",
journal = "Journal of Magnetism and Magnetic Materials",
title = "Gd2O3 nanoparticles stabilized by hydrothermally modified dextrose for positive contrast magnetic resonance imaging",
volume = "403",
pages = "118-126",
doi = "10.1016/j.jmmm.2015.11.075"
}
Babić-Stojić, B. S., Jokanović, V. R., Milivojević, D., Pozek, M., Jaglicic, Z., Makovec, D., Arsikin, K. M.,& Paunović, V. G.. (2016). Gd2O3 nanoparticles stabilized by hydrothermally modified dextrose for positive contrast magnetic resonance imaging. in Journal of Magnetism and Magnetic Materials
Elsevier., 403, 118-126.
https://doi.org/10.1016/j.jmmm.2015.11.075
Babić-Stojić BS, Jokanović VR, Milivojević D, Pozek M, Jaglicic Z, Makovec D, Arsikin KM, Paunović VG. Gd2O3 nanoparticles stabilized by hydrothermally modified dextrose for positive contrast magnetic resonance imaging. in Journal of Magnetism and Magnetic Materials. 2016;403:118-126.
doi:10.1016/j.jmmm.2015.11.075 .
Babić-Stojić, Branka S., Jokanović, Vukoman R., Milivojević, Dušan, Pozek, Miroslav, Jaglicic, Zvonko, Makovec, Darko, Arsikin, Katarina M., Paunović, Verica G., "Gd2O3 nanoparticles stabilized by hydrothermally modified dextrose for positive contrast magnetic resonance imaging" in Journal of Magnetism and Magnetic Materials, 403 (2016):118-126,
https://doi.org/10.1016/j.jmmm.2015.11.075 . .
3
15
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16

Graphene Quantum Dots Attenuate Concanavalin A-Induced Hepatitis

Volarevic, V.; Paunović, Verica G.; Marković, Zoran M.; Marković-Simović, Bojana; Misirkić-Marjanović, Maja; Todorović-Marković, Biljana; Bojic, S.; Vucicevic, L.; Jovanović, Svetlana P.; Arsenijević, Nebojša N.; Holclajtner-Antunović, Ivanka D.; Milosavljević, Momir; Dramićanin, Miroslav; Kravić-Stevović, Tamara K.; Ćirić, Darko; Lukić, M. L.; Trajković, Vladimir S.

(2015)

TY  - CONF
AU  - Volarevic, V.
AU  - Paunović, Verica G.
AU  - Marković, Zoran M.
AU  - Marković-Simović, Bojana
AU  - Misirkić-Marjanović, Maja
AU  - Todorović-Marković, Biljana
AU  - Bojic, S.
AU  - Vucicevic, L.
AU  - Jovanović, Svetlana P.
AU  - Arsenijević, Nebojša N.
AU  - Holclajtner-Antunović, Ivanka D.
AU  - Milosavljević, Momir
AU  - Dramićanin, Miroslav
AU  - Kravić-Stevović, Tamara K.
AU  - Ćirić, Darko
AU  - Lukić, M. L.
AU  - Trajković, Vladimir S.
PY  - 2015
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/7082
C3  - Journal of Hepatology
T1  - Graphene Quantum Dots Attenuate Concanavalin A-Induced Hepatitis
VL  - 62
SP  - S483
EP  - S484
DO  - 10.1016/S0168-8278(15)30665-6
ER  - 
@conference{
author = "Volarevic, V. and Paunović, Verica G. and Marković, Zoran M. and Marković-Simović, Bojana and Misirkić-Marjanović, Maja and Todorović-Marković, Biljana and Bojic, S. and Vucicevic, L. and Jovanović, Svetlana P. and Arsenijević, Nebojša N. and Holclajtner-Antunović, Ivanka D. and Milosavljević, Momir and Dramićanin, Miroslav and Kravić-Stevović, Tamara K. and Ćirić, Darko and Lukić, M. L. and Trajković, Vladimir S.",
year = "2015",
journal = "Journal of Hepatology",
title = "Graphene Quantum Dots Attenuate Concanavalin A-Induced Hepatitis",
volume = "62",
pages = "S483-S484",
doi = "10.1016/S0168-8278(15)30665-6"
}
Volarevic, V., Paunović, V. G., Marković, Z. M., Marković-Simović, B., Misirkić-Marjanović, M., Todorović-Marković, B., Bojic, S., Vucicevic, L., Jovanović, S. P., Arsenijević, N. N., Holclajtner-Antunović, I. D., Milosavljević, M., Dramićanin, M., Kravić-Stevović, T. K., Ćirić, D., Lukić, M. L.,& Trajković, V. S.. (2015). Graphene Quantum Dots Attenuate Concanavalin A-Induced Hepatitis. in Journal of Hepatology, 62, S483-S484.
https://doi.org/10.1016/S0168-8278(15)30665-6
Volarevic V, Paunović VG, Marković ZM, Marković-Simović B, Misirkić-Marjanović M, Todorović-Marković B, Bojic S, Vucicevic L, Jovanović SP, Arsenijević NN, Holclajtner-Antunović ID, Milosavljević M, Dramićanin M, Kravić-Stevović TK, Ćirić D, Lukić ML, Trajković VS. Graphene Quantum Dots Attenuate Concanavalin A-Induced Hepatitis. in Journal of Hepatology. 2015;62:S483-S484.
doi:10.1016/S0168-8278(15)30665-6 .
Volarevic, V., Paunović, Verica G., Marković, Zoran M., Marković-Simović, Bojana, Misirkić-Marjanović, Maja, Todorović-Marković, Biljana, Bojic, S., Vucicevic, L., Jovanović, Svetlana P., Arsenijević, Nebojša N., Holclajtner-Antunović, Ivanka D., Milosavljević, Momir, Dramićanin, Miroslav, Kravić-Stevović, Tamara K., Ćirić, Darko, Lukić, M. L., Trajković, Vladimir S., "Graphene Quantum Dots Attenuate Concanavalin A-Induced Hepatitis" in Journal of Hepatology, 62 (2015):S483-S484,
https://doi.org/10.1016/S0168-8278(15)30665-6 . .

Large Graphene Quantum Dots Alleviate Immune-Mediated Liver Damage

Volarevic, Vladislav; Paunović, Verica G.; Marković, Zoran M.; Marković-Simović, Bojana; Misirkić-Marjanović, Maja; Todorović-Marković, Biljana; Bojic, Sanja; Vucicevic, Ljubica; Jovanović, Svetlana P.; Arsenijević, Nebojša N.; Holclajtner-Antunović, Ivanka D.; Milosavljević, Momir; Dramićanin, Miroslav; Kravić-Stevović, Tamara K.; Ćirić, Darko; Lukić, Miodrag L.; Trajković, Vladimir S.

(2014)

TY  - JOUR
AU  - Volarevic, Vladislav
AU  - Paunović, Verica G.
AU  - Marković, Zoran M.
AU  - Marković-Simović, Bojana
AU  - Misirkić-Marjanović, Maja
AU  - Todorović-Marković, Biljana
AU  - Bojic, Sanja
AU  - Vucicevic, Ljubica
AU  - Jovanović, Svetlana P.
AU  - Arsenijević, Nebojša N.
AU  - Holclajtner-Antunović, Ivanka D.
AU  - Milosavljević, Momir
AU  - Dramićanin, Miroslav
AU  - Kravić-Stevović, Tamara K.
AU  - Ćirić, Darko
AU  - Lukić, Miodrag L.
AU  - Trajković, Vladimir S.
PY  - 2014
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/324
AB  - We investigated the effect of large (40 nm) graphene quantum dots (GQDs) in concanavalin A (Con A; 12 mg/kg i.v.)-induced mouse hepatitis, a T cell-mediated liver injury resembling fulminant hepatitis in humans. Intravenously injected GQDs (50 mg/kg) accumulated in liver and reduced Con A-mediated liver damage, as demonstrated by histopathological analysis and a decrease in liver lipid peroxidation and serum levels of liver transaminases. The cleavage of apoptotic markers caspase-3/PARP and mRNA levels of proapoptotic mediators Puma, Noxa, Bax, Bak1, Bim, Apaf1, and p21, as well as LC3-I conversion to autophagosome-associated LC3-II and expression of autophagy-related (Atg) genes Atg4b, Atg7, Atg12, and beclin-1, were attenuated by GQDs, indicating a decrease in both apoptosis and autophagy in the liver tissue. This was associated with the reduced liver infiltration of immune cells, particularly the T cells producing proinflammatory cytokine IFN-?, and a decrease in IFN-gamma serum levels. In the spleen of GQD-exposed mice, mRNA expression of IFN-? and its transcription factor T-bet was reduced, while that of the IL-33 ligand ST2 was increased. The hepatoprotective effect of GQDs was less pronounced in ST2-deficient mice, indicating that it might depend on ST2 upregulation. In vitro, GQDs inhibited splenocyte IFN-gamma production, reduced the activation of extracellular signal-regulated kinase in macrophage and T cell lines, inhibited macrophage production of the free radical nitric oxide, and reduced its cytotoxicity toward hepatocyte cell line HepG2. Therefore, GQDs alleviate immune-mediated fulminant hepatitis by interfering with T cell and macrophage activation and possibly by exerting a direct hepatoprotective effect.
T2  - ACS Nano
T1  - Large Graphene Quantum Dots Alleviate Immune-Mediated Liver Damage
VL  - 8
IS  - 12
SP  - 12098
EP  - 12109
DO  - 10.1021/nn502466z
ER  - 
@article{
author = "Volarevic, Vladislav and Paunović, Verica G. and Marković, Zoran M. and Marković-Simović, Bojana and Misirkić-Marjanović, Maja and Todorović-Marković, Biljana and Bojic, Sanja and Vucicevic, Ljubica and Jovanović, Svetlana P. and Arsenijević, Nebojša N. and Holclajtner-Antunović, Ivanka D. and Milosavljević, Momir and Dramićanin, Miroslav and Kravić-Stevović, Tamara K. and Ćirić, Darko and Lukić, Miodrag L. and Trajković, Vladimir S.",
year = "2014",
abstract = "We investigated the effect of large (40 nm) graphene quantum dots (GQDs) in concanavalin A (Con A; 12 mg/kg i.v.)-induced mouse hepatitis, a T cell-mediated liver injury resembling fulminant hepatitis in humans. Intravenously injected GQDs (50 mg/kg) accumulated in liver and reduced Con A-mediated liver damage, as demonstrated by histopathological analysis and a decrease in liver lipid peroxidation and serum levels of liver transaminases. The cleavage of apoptotic markers caspase-3/PARP and mRNA levels of proapoptotic mediators Puma, Noxa, Bax, Bak1, Bim, Apaf1, and p21, as well as LC3-I conversion to autophagosome-associated LC3-II and expression of autophagy-related (Atg) genes Atg4b, Atg7, Atg12, and beclin-1, were attenuated by GQDs, indicating a decrease in both apoptosis and autophagy in the liver tissue. This was associated with the reduced liver infiltration of immune cells, particularly the T cells producing proinflammatory cytokine IFN-?, and a decrease in IFN-gamma serum levels. In the spleen of GQD-exposed mice, mRNA expression of IFN-? and its transcription factor T-bet was reduced, while that of the IL-33 ligand ST2 was increased. The hepatoprotective effect of GQDs was less pronounced in ST2-deficient mice, indicating that it might depend on ST2 upregulation. In vitro, GQDs inhibited splenocyte IFN-gamma production, reduced the activation of extracellular signal-regulated kinase in macrophage and T cell lines, inhibited macrophage production of the free radical nitric oxide, and reduced its cytotoxicity toward hepatocyte cell line HepG2. Therefore, GQDs alleviate immune-mediated fulminant hepatitis by interfering with T cell and macrophage activation and possibly by exerting a direct hepatoprotective effect.",
journal = "ACS Nano",
title = "Large Graphene Quantum Dots Alleviate Immune-Mediated Liver Damage",
volume = "8",
number = "12",
pages = "12098-12109",
doi = "10.1021/nn502466z"
}
Volarevic, V., Paunović, V. G., Marković, Z. M., Marković-Simović, B., Misirkić-Marjanović, M., Todorović-Marković, B., Bojic, S., Vucicevic, L., Jovanović, S. P., Arsenijević, N. N., Holclajtner-Antunović, I. D., Milosavljević, M., Dramićanin, M., Kravić-Stevović, T. K., Ćirić, D., Lukić, M. L.,& Trajković, V. S.. (2014). Large Graphene Quantum Dots Alleviate Immune-Mediated Liver Damage. in ACS Nano, 8(12), 12098-12109.
https://doi.org/10.1021/nn502466z
Volarevic V, Paunović VG, Marković ZM, Marković-Simović B, Misirkić-Marjanović M, Todorović-Marković B, Bojic S, Vucicevic L, Jovanović SP, Arsenijević NN, Holclajtner-Antunović ID, Milosavljević M, Dramićanin M, Kravić-Stevović TK, Ćirić D, Lukić ML, Trajković VS. Large Graphene Quantum Dots Alleviate Immune-Mediated Liver Damage. in ACS Nano. 2014;8(12):12098-12109.
doi:10.1021/nn502466z .
Volarevic, Vladislav, Paunović, Verica G., Marković, Zoran M., Marković-Simović, Bojana, Misirkić-Marjanović, Maja, Todorović-Marković, Biljana, Bojic, Sanja, Vucicevic, Ljubica, Jovanović, Svetlana P., Arsenijević, Nebojša N., Holclajtner-Antunović, Ivanka D., Milosavljević, Momir, Dramićanin, Miroslav, Kravić-Stevović, Tamara K., Ćirić, Darko, Lukić, Miodrag L., Trajković, Vladimir S., "Large Graphene Quantum Dots Alleviate Immune-Mediated Liver Damage" in ACS Nano, 8, no. 12 (2014):12098-12109,
https://doi.org/10.1021/nn502466z . .
4
48
48
49

Photodynamic antibacterial effect of graphene quantum dots

Ristić, Biljana Z.; Milenković, Marina M.; Dakic, Ivana R.; Todorović-Marković, Biljana; Milosavljević, Momir; Budimir, Milica; Paunović, Verica G.; Dramićanin, Miroslav; Marković, Zoran M.; Trajković, Vladimir S.

(2014)

TY  - JOUR
AU  - Ristić, Biljana Z.
AU  - Milenković, Marina M.
AU  - Dakic, Ivana R.
AU  - Todorović-Marković, Biljana
AU  - Milosavljević, Momir
AU  - Budimir, Milica
AU  - Paunović, Verica G.
AU  - Dramićanin, Miroslav
AU  - Marković, Zoran M.
AU  - Trajković, Vladimir S.
PY  - 2014
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/5964
AB  - Synthesis of new antibacterial agents is becoming increasingly important in light of the emerging antibiotic resistance. In the present study we report that electrochemically produced graphene quantum dots (GQD), a new class of carbon nanoparticles, generate reactive oxygen species when photoexcited (470 nm, 1 W), and kill two strains of pathogenic bacteria, methicillin-resistant Staphylococcus aureus and Escherichia coli. Bacterial killing was demonstrated by the reduction in number of bacterial colonies in a standard plate count method, the increase in propidium iodide uptake confirming the cell membrane damage, as well as by morphological defects visualized by atomic force microscopy. The induction of oxidative stress in bacteria exposed to photoexcited GQD was confirmed by staining with a redox-sensitive fluorochrome dihydrorhodamine 123. Neither GQD nor light exposure alone were able to cause oxidative stress and reduce the viability of bacteria. Importantly, mouse spleen cells were markedly less sensitive in the same experimental conditions, thus indicating a fairly selective antibacterial photodynamic action of GQD. (C) 2014 Elsevier Ltd. All rights reserved.
T2  - Biomaterials
T1  - Photodynamic antibacterial effect of graphene quantum dots
VL  - 35
IS  - 15
SP  - 4428
EP  - 4435
DO  - 10.1016/j.biomaterials.2014.02.014
ER  - 
@article{
author = "Ristić, Biljana Z. and Milenković, Marina M. and Dakic, Ivana R. and Todorović-Marković, Biljana and Milosavljević, Momir and Budimir, Milica and Paunović, Verica G. and Dramićanin, Miroslav and Marković, Zoran M. and Trajković, Vladimir S.",
year = "2014",
abstract = "Synthesis of new antibacterial agents is becoming increasingly important in light of the emerging antibiotic resistance. In the present study we report that electrochemically produced graphene quantum dots (GQD), a new class of carbon nanoparticles, generate reactive oxygen species when photoexcited (470 nm, 1 W), and kill two strains of pathogenic bacteria, methicillin-resistant Staphylococcus aureus and Escherichia coli. Bacterial killing was demonstrated by the reduction in number of bacterial colonies in a standard plate count method, the increase in propidium iodide uptake confirming the cell membrane damage, as well as by morphological defects visualized by atomic force microscopy. The induction of oxidative stress in bacteria exposed to photoexcited GQD was confirmed by staining with a redox-sensitive fluorochrome dihydrorhodamine 123. Neither GQD nor light exposure alone were able to cause oxidative stress and reduce the viability of bacteria. Importantly, mouse spleen cells were markedly less sensitive in the same experimental conditions, thus indicating a fairly selective antibacterial photodynamic action of GQD. (C) 2014 Elsevier Ltd. All rights reserved.",
journal = "Biomaterials",
title = "Photodynamic antibacterial effect of graphene quantum dots",
volume = "35",
number = "15",
pages = "4428-4435",
doi = "10.1016/j.biomaterials.2014.02.014"
}
Ristić, B. Z., Milenković, M. M., Dakic, I. R., Todorović-Marković, B., Milosavljević, M., Budimir, M., Paunović, V. G., Dramićanin, M., Marković, Z. M.,& Trajković, V. S.. (2014). Photodynamic antibacterial effect of graphene quantum dots. in Biomaterials, 35(15), 4428-4435.
https://doi.org/10.1016/j.biomaterials.2014.02.014
Ristić BZ, Milenković MM, Dakic IR, Todorović-Marković B, Milosavljević M, Budimir M, Paunović VG, Dramićanin M, Marković ZM, Trajković VS. Photodynamic antibacterial effect of graphene quantum dots. in Biomaterials. 2014;35(15):4428-4435.
doi:10.1016/j.biomaterials.2014.02.014 .
Ristić, Biljana Z., Milenković, Marina M., Dakic, Ivana R., Todorović-Marković, Biljana, Milosavljević, Momir, Budimir, Milica, Paunović, Verica G., Dramićanin, Miroslav, Marković, Zoran M., Trajković, Vladimir S., "Photodynamic antibacterial effect of graphene quantum dots" in Biomaterials, 35, no. 15 (2014):4428-4435,
https://doi.org/10.1016/j.biomaterials.2014.02.014 . .
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NMR relaxometric properties and cytotoxicity of Gd2O3 nanoparticle suspensions in an organic liquid

Babić-Stojić, Branka S.; Jokanović, Vukoman R.; Milivojević, Dušan; Pozek, Miroslav; Jaglicic, Zvonko; Makovec, Darko; Arsikin, Katarina M.; Paunović, Verica G.

(2014)

TY  - JOUR
AU  - Babić-Stojić, Branka S.
AU  - Jokanović, Vukoman R.
AU  - Milivojević, Dušan
AU  - Pozek, Miroslav
AU  - Jaglicic, Zvonko
AU  - Makovec, Darko
AU  - Arsikin, Katarina M.
AU  - Paunović, Verica G.
PY  - 2014
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/414
AB  - Gd2O3 nanoparticles and their agglomerates from approximately 10 to 80 nm in size suspended in an organic liquid were synthesized via polyol route. The reaction between diethylene glycol and added acetic acid, which occurred simultaneously with the synthesis of Gd2O3 nanoparticles, was catalyzed by sodium bisulfate to transform as much as possible diethylene glycol in corresponding ester at the end of complete reaction. The produced nanosized material of gadolinium oxide was investigated by TEM, DLS, FTIR spectroscopy, and NMR relaxometry. Biological evaluation of this material was done by MTT and crystal violet assays to determine the cell viability. Longitudinal and transverse relaxivities of water-diluted Gd2O3 nanoparticle suspensions estimated to be r(1) = 13.6 and r(2) = 14.7 s(-1) mM(-1) are about three times higher compared to the relaxivities obtained for standard contrast agent Gd-DTPA (Magnevist). Good MRI signal intensities of the water-diluted Gd2O3 nanoparticle suspensions were recorded in the Gd concentration range 0.2-0.3 mM for which the suspensions were not toxic exhibiting simultaneously higher signal intensities than those for Magnevist in the Gd concentration range 0.4-1 mM for which this standard contrast agent was not toxic. These properties make the produced Gd2O3 nanoparticle material promising for potential application as MRI contrast agent.
T2  - Journal of Nanoparticle Research
T1  - NMR relaxometric properties and cytotoxicity of Gd2O3 nanoparticle suspensions in an organic liquid
VL  - 16
IS  - 10
DO  - 10.1007/s11051-014-2663-0
ER  - 
@article{
author = "Babić-Stojić, Branka S. and Jokanović, Vukoman R. and Milivojević, Dušan and Pozek, Miroslav and Jaglicic, Zvonko and Makovec, Darko and Arsikin, Katarina M. and Paunović, Verica G.",
year = "2014",
abstract = "Gd2O3 nanoparticles and their agglomerates from approximately 10 to 80 nm in size suspended in an organic liquid were synthesized via polyol route. The reaction between diethylene glycol and added acetic acid, which occurred simultaneously with the synthesis of Gd2O3 nanoparticles, was catalyzed by sodium bisulfate to transform as much as possible diethylene glycol in corresponding ester at the end of complete reaction. The produced nanosized material of gadolinium oxide was investigated by TEM, DLS, FTIR spectroscopy, and NMR relaxometry. Biological evaluation of this material was done by MTT and crystal violet assays to determine the cell viability. Longitudinal and transverse relaxivities of water-diluted Gd2O3 nanoparticle suspensions estimated to be r(1) = 13.6 and r(2) = 14.7 s(-1) mM(-1) are about three times higher compared to the relaxivities obtained for standard contrast agent Gd-DTPA (Magnevist). Good MRI signal intensities of the water-diluted Gd2O3 nanoparticle suspensions were recorded in the Gd concentration range 0.2-0.3 mM for which the suspensions were not toxic exhibiting simultaneously higher signal intensities than those for Magnevist in the Gd concentration range 0.4-1 mM for which this standard contrast agent was not toxic. These properties make the produced Gd2O3 nanoparticle material promising for potential application as MRI contrast agent.",
journal = "Journal of Nanoparticle Research",
title = "NMR relaxometric properties and cytotoxicity of Gd2O3 nanoparticle suspensions in an organic liquid",
volume = "16",
number = "10",
doi = "10.1007/s11051-014-2663-0"
}
Babić-Stojić, B. S., Jokanović, V. R., Milivojević, D., Pozek, M., Jaglicic, Z., Makovec, D., Arsikin, K. M.,& Paunović, V. G.. (2014). NMR relaxometric properties and cytotoxicity of Gd2O3 nanoparticle suspensions in an organic liquid. in Journal of Nanoparticle Research, 16(10).
https://doi.org/10.1007/s11051-014-2663-0
Babić-Stojić BS, Jokanović VR, Milivojević D, Pozek M, Jaglicic Z, Makovec D, Arsikin KM, Paunović VG. NMR relaxometric properties and cytotoxicity of Gd2O3 nanoparticle suspensions in an organic liquid. in Journal of Nanoparticle Research. 2014;16(10).
doi:10.1007/s11051-014-2663-0 .
Babić-Stojić, Branka S., Jokanović, Vukoman R., Milivojević, Dušan, Pozek, Miroslav, Jaglicic, Zvonko, Makovec, Darko, Arsikin, Katarina M., Paunović, Verica G., "NMR relaxometric properties and cytotoxicity of Gd2O3 nanoparticle suspensions in an organic liquid" in Journal of Nanoparticle Research, 16, no. 10 (2014),
https://doi.org/10.1007/s11051-014-2663-0 . .
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Influence of mechanical activation on electrical properties of barium-zinc-titanate ceramics sintered at 1100A degrees C

Obradović, Nina; Filipović, Suzana; Mitrić, Miodrag; Pavlović, Vladimir B.; Paunović, Verica G.; Kosanović, Darko; Balac, I.; Ristic, M. M.

(2012)

TY  - JOUR
AU  - Obradović, Nina
AU  - Filipović, Suzana
AU  - Mitrić, Miodrag
AU  - Pavlović, Vladimir B.
AU  - Paunović, Verica G.
AU  - Kosanović, Darko
AU  - Balac, I.
AU  - Ristic, M. M.
PY  - 2012
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/4809
AB  - Starting mixtures of BaCO3, ZnO, and TiO2 powders are mechanically activated in a planetary ball mill for various periods of time. The powders obtained are sintered isothermally at 1100A degrees C for 120 min. Non-isothermal sintering process is followed by measurements with a sensitive dilatometer, as well. Results of microstructure characterization using SEM analyses along with DTA analyses are provided. These results are correlated with the values of electric resistivity, capacitance, and loss tangent of the samples, and it is found that with increasing milling time, the increase in values of electrical properties is noticed.
T2  - Powder Metallurgy and Metal Ceramics
T1  - Influence of mechanical activation on electrical properties of barium-zinc-titanate ceramics sintered at 1100A degrees C
VL  - 50
IS  - 11-12
SP  - 714
EP  - 718
DO  - 10.1007/s11106-012-9380-y
ER  - 
@article{
author = "Obradović, Nina and Filipović, Suzana and Mitrić, Miodrag and Pavlović, Vladimir B. and Paunović, Verica G. and Kosanović, Darko and Balac, I. and Ristic, M. M.",
year = "2012",
abstract = "Starting mixtures of BaCO3, ZnO, and TiO2 powders are mechanically activated in a planetary ball mill for various periods of time. The powders obtained are sintered isothermally at 1100A degrees C for 120 min. Non-isothermal sintering process is followed by measurements with a sensitive dilatometer, as well. Results of microstructure characterization using SEM analyses along with DTA analyses are provided. These results are correlated with the values of electric resistivity, capacitance, and loss tangent of the samples, and it is found that with increasing milling time, the increase in values of electrical properties is noticed.",
journal = "Powder Metallurgy and Metal Ceramics",
title = "Influence of mechanical activation on electrical properties of barium-zinc-titanate ceramics sintered at 1100A degrees C",
volume = "50",
number = "11-12",
pages = "714-718",
doi = "10.1007/s11106-012-9380-y"
}
Obradović, N., Filipović, S., Mitrić, M., Pavlović, V. B., Paunović, V. G., Kosanović, D., Balac, I.,& Ristic, M. M.. (2012). Influence of mechanical activation on electrical properties of barium-zinc-titanate ceramics sintered at 1100A degrees C. in Powder Metallurgy and Metal Ceramics, 50(11-12), 714-718.
https://doi.org/10.1007/s11106-012-9380-y
Obradović N, Filipović S, Mitrić M, Pavlović VB, Paunović VG, Kosanović D, Balac I, Ristic MM. Influence of mechanical activation on electrical properties of barium-zinc-titanate ceramics sintered at 1100A degrees C. in Powder Metallurgy and Metal Ceramics. 2012;50(11-12):714-718.
doi:10.1007/s11106-012-9380-y .
Obradović, Nina, Filipović, Suzana, Mitrić, Miodrag, Pavlović, Vladimir B., Paunović, Verica G., Kosanović, Darko, Balac, I., Ristic, M. M., "Influence of mechanical activation on electrical properties of barium-zinc-titanate ceramics sintered at 1100A degrees C" in Powder Metallurgy and Metal Ceramics, 50, no. 11-12 (2012):714-718,
https://doi.org/10.1007/s11106-012-9380-y . .

Structural and Electrical Properties of Sintered Barium-Zinc-Titanate Ceramics

Obradović, Nina; Filipović, Suzana; Pavlović, Vladimir B.; Paunović, Verica G.; Mitrić, Miodrag; Ristic, M. M.

(2011)

TY  - JOUR
AU  - Obradović, Nina
AU  - Filipović, Suzana
AU  - Pavlović, Vladimir B.
AU  - Paunović, Verica G.
AU  - Mitrić, Miodrag
AU  - Ristic, M. M.
PY  - 2011
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/6925
AB  - The aim of this work was an investigation of structural and electrical properties of sintered barium-zinc-titanate ceramics. Mixtures of BaCO(3), ZnO and TiO(2) were mechanically activated in a planetary ball mill up to 80 minutes and sintered isothermally in air for 120 minutes at 1300 degrees C. The phase composition in the BaCO(3)-ZnO-TiO(2) system after milling and sintering was analyzed using the XRD method. The existence of pure barium-zinc-titanate has been registered. Microstructure analyses were performed using SEM. The results of electric resistivity, capacitance and loss tangent of the sintered samples were correlated with the XRD and SEM results.
T2  - Acta Physica Polonica. Series A: General Physics, Physics of Condensed Matter, Optics and Quantum Electronics, Atomic and Molecular Physics, Applied Physics
T1  - Structural and Electrical Properties of Sintered Barium-Zinc-Titanate Ceramics
VL  - 120
IS  - 2
SP  - 322
EP  - 325
DO  - 10.12693/APhysPolA.120.322
ER  - 
@article{
author = "Obradović, Nina and Filipović, Suzana and Pavlović, Vladimir B. and Paunović, Verica G. and Mitrić, Miodrag and Ristic, M. M.",
year = "2011",
abstract = "The aim of this work was an investigation of structural and electrical properties of sintered barium-zinc-titanate ceramics. Mixtures of BaCO(3), ZnO and TiO(2) were mechanically activated in a planetary ball mill up to 80 minutes and sintered isothermally in air for 120 minutes at 1300 degrees C. The phase composition in the BaCO(3)-ZnO-TiO(2) system after milling and sintering was analyzed using the XRD method. The existence of pure barium-zinc-titanate has been registered. Microstructure analyses were performed using SEM. The results of electric resistivity, capacitance and loss tangent of the sintered samples were correlated with the XRD and SEM results.",
journal = "Acta Physica Polonica. Series A: General Physics, Physics of Condensed Matter, Optics and Quantum Electronics, Atomic and Molecular Physics, Applied Physics",
title = "Structural and Electrical Properties of Sintered Barium-Zinc-Titanate Ceramics",
volume = "120",
number = "2",
pages = "322-325",
doi = "10.12693/APhysPolA.120.322"
}
Obradović, N., Filipović, S., Pavlović, V. B., Paunović, V. G., Mitrić, M.,& Ristic, M. M.. (2011). Structural and Electrical Properties of Sintered Barium-Zinc-Titanate Ceramics. in Acta Physica Polonica. Series A: General Physics, Physics of Condensed Matter, Optics and Quantum Electronics, Atomic and Molecular Physics, Applied Physics, 120(2), 322-325.
https://doi.org/10.12693/APhysPolA.120.322
Obradović N, Filipović S, Pavlović VB, Paunović VG, Mitrić M, Ristic MM. Structural and Electrical Properties of Sintered Barium-Zinc-Titanate Ceramics. in Acta Physica Polonica. Series A: General Physics, Physics of Condensed Matter, Optics and Quantum Electronics, Atomic and Molecular Physics, Applied Physics. 2011;120(2):322-325.
doi:10.12693/APhysPolA.120.322 .
Obradović, Nina, Filipović, Suzana, Pavlović, Vladimir B., Paunović, Verica G., Mitrić, Miodrag, Ristic, M. M., "Structural and Electrical Properties of Sintered Barium-Zinc-Titanate Ceramics" in Acta Physica Polonica. Series A: General Physics, Physics of Condensed Matter, Optics and Quantum Electronics, Atomic and Molecular Physics, Applied Physics, 120, no. 2 (2011):322-325,
https://doi.org/10.12693/APhysPolA.120.322 . .
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