Sabo, Tibor J.

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orcid::0000-0002-9866-327X
  • Sabo, Tibor J. (11)
  • Sabo, Ljubica (1)

Author's Bibliography

Toxicity study of DE-EDCP as a potential drug for cancer therapy: Toxicity profile of DE-EDCP

Stanković, Dragana; Ristić, Slavica M.; Vukadinović, Aleksandar; Mirković, Marija D.; Vladimirov, Sandra S.; Milanović, Zorana; Radović, Magdalena; Mijović, Milica; Stanković, Dalibor M.; Sabo, Tibor J.; Vranješ-Đurić, Sanja; Janković, Drina

(2019)

TY  - JOUR
AU  - Stanković, Dragana
AU  - Ristić, Slavica M.
AU  - Vukadinović, Aleksandar
AU  - Mirković, Marija D.
AU  - Vladimirov, Sandra S.
AU  - Milanović, Zorana
AU  - Radović, Magdalena
AU  - Mijović, Milica
AU  - Stanković, Dalibor M.
AU  - Sabo, Tibor J.
AU  - Vranješ-Đurić, Sanja
AU  - Janković, Drina
PY  - 2019
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8492
AB  - It was reported that novel O,O′-diethyl-(S, S)-ethylenediamine-N,N′-di-2-(3-cyclohexyl) propanoate dihydrochloride (DE-EDCP) displayed in vitro antiproliferative activity on several human and mouse cancer cell lines, which was comparable to that of the prototypical anticancer drug cisplatin. In order to reveal its toxicity profile, acute and repeated-dose toxicity studies were performed in Naval Medical Research Institute (NMRI) Han mice. The intravenous LD50 values of DE-EDCP were found to be 95.3 and 101.3 mg/kg body weight in female and male mice, respectively. In the subacute toxicity study, DE-EDCP was administered intravenously at the doses of 15, 25, and 40 mg/kg/day for a period of 28 days. There were no adverse effects on general condition, growth, feed and water consumption, and hematological parameters. There was a significant increase in urea and alanine aminotransferase in female mice and aspartate aminotransferase and alkaline phosphatase in both genders in 40 mg/kg/day dose-treated group. The histopathological changes confined to the liver and kidney, but in other organs were not found. Satellite group revealed that changes in the kidney and liver were less pronounced, suggesting their reversibility. Interactions with DNA could also be of importance for understanding DE-EDCP toxic side effects. Hyperchromic effect obtained with ultraviolet–visible, suggested electrostatic interactions between DE-EDCP and calf thymus DNA. The toxicity testing of DE-EDCP was conducted to predict human outcomes. © The Author(s) 2018.
T2  - Human and Experimental Toxicology
T1  - Toxicity study of DE-EDCP as a potential drug for cancer therapy: Toxicity profile of DE-EDCP
VL  - 38
IS  - 4
SP  - 466
EP  - 481
DO  - 10.1177/0960327118819047
ER  - 
@article{
author = "Stanković, Dragana and Ristić, Slavica M. and Vukadinović, Aleksandar and Mirković, Marija D. and Vladimirov, Sandra S. and Milanović, Zorana and Radović, Magdalena and Mijović, Milica and Stanković, Dalibor M. and Sabo, Tibor J. and Vranješ-Đurić, Sanja and Janković, Drina",
year = "2019",
abstract = "It was reported that novel O,O′-diethyl-(S, S)-ethylenediamine-N,N′-di-2-(3-cyclohexyl) propanoate dihydrochloride (DE-EDCP) displayed in vitro antiproliferative activity on several human and mouse cancer cell lines, which was comparable to that of the prototypical anticancer drug cisplatin. In order to reveal its toxicity profile, acute and repeated-dose toxicity studies were performed in Naval Medical Research Institute (NMRI) Han mice. The intravenous LD50 values of DE-EDCP were found to be 95.3 and 101.3 mg/kg body weight in female and male mice, respectively. In the subacute toxicity study, DE-EDCP was administered intravenously at the doses of 15, 25, and 40 mg/kg/day for a period of 28 days. There were no adverse effects on general condition, growth, feed and water consumption, and hematological parameters. There was a significant increase in urea and alanine aminotransferase in female mice and aspartate aminotransferase and alkaline phosphatase in both genders in 40 mg/kg/day dose-treated group. The histopathological changes confined to the liver and kidney, but in other organs were not found. Satellite group revealed that changes in the kidney and liver were less pronounced, suggesting their reversibility. Interactions with DNA could also be of importance for understanding DE-EDCP toxic side effects. Hyperchromic effect obtained with ultraviolet–visible, suggested electrostatic interactions between DE-EDCP and calf thymus DNA. The toxicity testing of DE-EDCP was conducted to predict human outcomes. © The Author(s) 2018.",
journal = "Human and Experimental Toxicology",
title = "Toxicity study of DE-EDCP as a potential drug for cancer therapy: Toxicity profile of DE-EDCP",
volume = "38",
number = "4",
pages = "466-481",
doi = "10.1177/0960327118819047"
}
Stanković, D., Ristić, S. M., Vukadinović, A., Mirković, M. D., Vladimirov, S. S., Milanović, Z., Radović, M., Mijović, M., Stanković, D. M., Sabo, T. J., Vranješ-Đurić, S.,& Janković, D.. (2019). Toxicity study of DE-EDCP as a potential drug for cancer therapy: Toxicity profile of DE-EDCP. in Human and Experimental Toxicology, 38(4), 466-481.
https://doi.org/10.1177/0960327118819047
Stanković D, Ristić SM, Vukadinović A, Mirković MD, Vladimirov SS, Milanović Z, Radović M, Mijović M, Stanković DM, Sabo TJ, Vranješ-Đurić S, Janković D. Toxicity study of DE-EDCP as a potential drug for cancer therapy: Toxicity profile of DE-EDCP. in Human and Experimental Toxicology. 2019;38(4):466-481.
doi:10.1177/0960327118819047 .
Stanković, Dragana, Ristić, Slavica M., Vukadinović, Aleksandar, Mirković, Marija D., Vladimirov, Sandra S., Milanović, Zorana, Radović, Magdalena, Mijović, Milica, Stanković, Dalibor M., Sabo, Tibor J., Vranješ-Đurić, Sanja, Janković, Drina, "Toxicity study of DE-EDCP as a potential drug for cancer therapy: Toxicity profile of DE-EDCP" in Human and Experimental Toxicology, 38, no. 4 (2019):466-481,
https://doi.org/10.1177/0960327118819047 . .
1

Voltammetric Study of Antitumor Efficient Ethylenediamine-Type of Ligands

Mihajlović-Lalić, Ljiljana E.; Stanković, Dalibor M.; Poljarević, Jelena M.; Sabo, Tibor J.; Manojlović, Dragan D.

(2018)

TY  - JOUR
AU  - Mihajlović-Lalić, Ljiljana E.
AU  - Stanković, Dalibor M.
AU  - Poljarević, Jelena M.
AU  - Sabo, Tibor J.
AU  - Manojlović, Dragan D.
PY  - 2018
UR  - http://jes.ecsdl.org/lookup/doi/10.1149/2.1121810jes
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/7892
AB  - The electrochemical behavior of four dialkyl esters (methyl, ethyl, n-propyl and n-butyl) of (S,S)-α,α ′-(1,2-ethanediyldiimino)- bis[cyclohexanepropanoic acid] with moderate antitumor activity has been studied by cyclic voltammetry. I-E curves recorded at boron-doped diamond electrode in -2.00 < Ep < 0.00 V range show a single oxidative peak located in the -0.95 < Ep,a < -0.52 V region in a form of one-electron wave. The electrochemical processes appear to be irreversible for all compounds except for the compound with methyl substituent which demonstrates well-defined reversible electron transfer. Derivatives with bulkier moieties are easier to oxidize. For all investigated compounds an amine-centered redox process is dominant. Further investigation indicates that electrochemical reaction is diffusion controlled, chemically irreversible process. The results are discussed in terms of linking their electrochemical activity to antitumor effect. © 2018 The Electrochemical Society.
T2  - Journal of The Electrochemical Society
T1  - Voltammetric Study of Antitumor Efficient Ethylenediamine-Type of Ligands
VL  - 165
IS  - 10
SP  - G123
EP  - G127
DO  - 10.1149/2.1121810jes
ER  - 
@article{
author = "Mihajlović-Lalić, Ljiljana E. and Stanković, Dalibor M. and Poljarević, Jelena M. and Sabo, Tibor J. and Manojlović, Dragan D.",
year = "2018",
abstract = "The electrochemical behavior of four dialkyl esters (methyl, ethyl, n-propyl and n-butyl) of (S,S)-α,α ′-(1,2-ethanediyldiimino)- bis[cyclohexanepropanoic acid] with moderate antitumor activity has been studied by cyclic voltammetry. I-E curves recorded at boron-doped diamond electrode in -2.00 < Ep < 0.00 V range show a single oxidative peak located in the -0.95 < Ep,a < -0.52 V region in a form of one-electron wave. The electrochemical processes appear to be irreversible for all compounds except for the compound with methyl substituent which demonstrates well-defined reversible electron transfer. Derivatives with bulkier moieties are easier to oxidize. For all investigated compounds an amine-centered redox process is dominant. Further investigation indicates that electrochemical reaction is diffusion controlled, chemically irreversible process. The results are discussed in terms of linking their electrochemical activity to antitumor effect. © 2018 The Electrochemical Society.",
journal = "Journal of The Electrochemical Society",
title = "Voltammetric Study of Antitumor Efficient Ethylenediamine-Type of Ligands",
volume = "165",
number = "10",
pages = "G123-G127",
doi = "10.1149/2.1121810jes"
}
Mihajlović-Lalić, L. E., Stanković, D. M., Poljarević, J. M., Sabo, T. J.,& Manojlović, D. D.. (2018). Voltammetric Study of Antitumor Efficient Ethylenediamine-Type of Ligands. in Journal of The Electrochemical Society, 165(10), G123-G127.
https://doi.org/10.1149/2.1121810jes
Mihajlović-Lalić LE, Stanković DM, Poljarević JM, Sabo TJ, Manojlović DD. Voltammetric Study of Antitumor Efficient Ethylenediamine-Type of Ligands. in Journal of The Electrochemical Society. 2018;165(10):G123-G127.
doi:10.1149/2.1121810jes .
Mihajlović-Lalić, Ljiljana E., Stanković, Dalibor M., Poljarević, Jelena M., Sabo, Tibor J., Manojlović, Dragan D., "Voltammetric Study of Antitumor Efficient Ethylenediamine-Type of Ligands" in Journal of The Electrochemical Society, 165, no. 10 (2018):G123-G127,
https://doi.org/10.1149/2.1121810jes . .
1
1
1

Synthesis and biological evaluation of Tc-99m tricarbonyl complex of O,O -diethylethylenediamine-N,N -di-3-propanoate as potential tumour diagnostic agent

Lakić, Mladen; Sabo, Ljubica; Ristic, Slavica; Savić, Aleksandar; Petricevic, Sasa; Nikolić, Nadežda S.; Vukadinović, Aleksandar; Janković, Drina; Sabo, Tibor J.; Vranješ-Đurić, Sanja

(2016)

TY  - JOUR
AU  - Lakić, Mladen
AU  - Sabo, Ljubica
AU  - Ristic, Slavica
AU  - Savić, Aleksandar
AU  - Petricevic, Sasa
AU  - Nikolić, Nadežda S.
AU  - Vukadinović, Aleksandar
AU  - Janković, Drina
AU  - Sabo, Tibor J.
AU  - Vranješ-Đurić, Sanja
PY  - 2016
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/273
AB  - The extensive development of radiopharmaceuticals towards early tumour detection and treatment has increased the demand for new ligands with higher tumour selectivity. Research has been done on the potential of the novel O,O-diethylethylenediamine-N,N-di-3-propanoate (L) ligand as a radionuclide vehicle for tumour targeting. Under alkaline conditions, L hydrolyses and produces half ester ligand (L) and diacid ligand (L), with characteristic donor atom array N, N, O. Ligand L was successfully labelled with Tc-99m at pH=9 by coordination with the octahedral fac-[Tc-99m(CO)(3)(H2O)(3)](+) intermediate, forming the main radioproduct fac-[(TcL)-Tc-99m(CO)(3)] (Tc1). The Tc-99m complex showed a low lipophilic character (log P = 0.48) and low binding affinity to human serum albumin (2.51 +/- 0.48%). In vitro stability studies in saline and human plasma, as well as challenge studies with cysteine and histidine, revealed high stability of the complex during 24 h. Biodistribution studies of Tc1 in female C57BL/6 mice bearing B16/F1 melanoma metastases showed significant tumour uptake: 9.81 +/- 1.19% ID g(-1) in the liver, 5.87 +/- 0.54% ID g(-1) in the lungs and 3.17 +/- 0.33% ID g(-1) in the ovary at 30 min post-injection. Favourable physicochemical properties, satisfactory in vitro/in vivo stability and biodistribution profile in the experimental metastatic melanoma model indicate the possible application of the radiolabelled ligand in tumour diagnosis. Copyright (C) 2015 John Wiley and Sons, Ltd.
T2  - Applied Organometallic Chemistry
T1  - Synthesis and biological evaluation of Tc-99m tricarbonyl complex of O,O -diethylethylenediamine-N,N -di-3-propanoate as potential tumour diagnostic agent
VL  - 30
IS  - 2
SP  - 81
EP  - 88
DO  - 10.1002/aoc.3401
ER  - 
@article{
author = "Lakić, Mladen and Sabo, Ljubica and Ristic, Slavica and Savić, Aleksandar and Petricevic, Sasa and Nikolić, Nadežda S. and Vukadinović, Aleksandar and Janković, Drina and Sabo, Tibor J. and Vranješ-Đurić, Sanja",
year = "2016",
abstract = "The extensive development of radiopharmaceuticals towards early tumour detection and treatment has increased the demand for new ligands with higher tumour selectivity. Research has been done on the potential of the novel O,O-diethylethylenediamine-N,N-di-3-propanoate (L) ligand as a radionuclide vehicle for tumour targeting. Under alkaline conditions, L hydrolyses and produces half ester ligand (L) and diacid ligand (L), with characteristic donor atom array N, N, O. Ligand L was successfully labelled with Tc-99m at pH=9 by coordination with the octahedral fac-[Tc-99m(CO)(3)(H2O)(3)](+) intermediate, forming the main radioproduct fac-[(TcL)-Tc-99m(CO)(3)] (Tc1). The Tc-99m complex showed a low lipophilic character (log P = 0.48) and low binding affinity to human serum albumin (2.51 +/- 0.48%). In vitro stability studies in saline and human plasma, as well as challenge studies with cysteine and histidine, revealed high stability of the complex during 24 h. Biodistribution studies of Tc1 in female C57BL/6 mice bearing B16/F1 melanoma metastases showed significant tumour uptake: 9.81 +/- 1.19% ID g(-1) in the liver, 5.87 +/- 0.54% ID g(-1) in the lungs and 3.17 +/- 0.33% ID g(-1) in the ovary at 30 min post-injection. Favourable physicochemical properties, satisfactory in vitro/in vivo stability and biodistribution profile in the experimental metastatic melanoma model indicate the possible application of the radiolabelled ligand in tumour diagnosis. Copyright (C) 2015 John Wiley and Sons, Ltd.",
journal = "Applied Organometallic Chemistry",
title = "Synthesis and biological evaluation of Tc-99m tricarbonyl complex of O,O -diethylethylenediamine-N,N -di-3-propanoate as potential tumour diagnostic agent",
volume = "30",
number = "2",
pages = "81-88",
doi = "10.1002/aoc.3401"
}
Lakić, M., Sabo, L., Ristic, S., Savić, A., Petricevic, S., Nikolić, N. S., Vukadinović, A., Janković, D., Sabo, T. J.,& Vranješ-Đurić, S.. (2016). Synthesis and biological evaluation of Tc-99m tricarbonyl complex of O,O -diethylethylenediamine-N,N -di-3-propanoate as potential tumour diagnostic agent. in Applied Organometallic Chemistry, 30(2), 81-88.
https://doi.org/10.1002/aoc.3401
Lakić M, Sabo L, Ristic S, Savić A, Petricevic S, Nikolić NS, Vukadinović A, Janković D, Sabo TJ, Vranješ-Đurić S. Synthesis and biological evaluation of Tc-99m tricarbonyl complex of O,O -diethylethylenediamine-N,N -di-3-propanoate as potential tumour diagnostic agent. in Applied Organometallic Chemistry. 2016;30(2):81-88.
doi:10.1002/aoc.3401 .
Lakić, Mladen, Sabo, Ljubica, Ristic, Slavica, Savić, Aleksandar, Petricevic, Sasa, Nikolić, Nadežda S., Vukadinović, Aleksandar, Janković, Drina, Sabo, Tibor J., Vranješ-Đurić, Sanja, "Synthesis and biological evaluation of Tc-99m tricarbonyl complex of O,O -diethylethylenediamine-N,N -di-3-propanoate as potential tumour diagnostic agent" in Applied Organometallic Chemistry, 30, no. 2 (2016):81-88,
https://doi.org/10.1002/aoc.3401 . .
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8

Crystal structure of ethylenediammonium-N,N '-di-3-propionic acid tetrachloroplatinate(II), (CH2NH2(CH2)(2)COOH)(2)[PtCl4]

Kaluđerović, Goran N.; Bogdanović, Goran A.; Sabo, Tibor J.

(2006)

TY  - JOUR
AU  - Kaluđerović, Goran N.
AU  - Bogdanović, Goran A.
AU  - Sabo, Tibor J.
PY  - 2006
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3132
AB  - C8H18Cl4N2O4Pt, monoclinic, P12(1)/n1 (no. 14), a = 8.181(3) angstrom, b = 10.303(5) angstrom, c = 9.073(6) angstrom, beta = 103.2(1)degrees, V = 744.6 angstrom(3), Z = 2, R-gt(F) = 0.080, wR(ref)(F-2) = 0.247, T = 293 K.
T2  - Zeitschrift für Kristallographie - New Crystal Structures
T1  - Crystal structure of ethylenediammonium-N,N '-di-3-propionic acid tetrachloroplatinate(II), (CH2NH2(CH2)(2)COOH)(2)[PtCl4]
VL  - 221
IS  - 3
SP  - 345
EP  - 346
DO  - 10.1524/ncrs.2006.0103
ER  - 
@article{
author = "Kaluđerović, Goran N. and Bogdanović, Goran A. and Sabo, Tibor J.",
year = "2006",
abstract = "C8H18Cl4N2O4Pt, monoclinic, P12(1)/n1 (no. 14), a = 8.181(3) angstrom, b = 10.303(5) angstrom, c = 9.073(6) angstrom, beta = 103.2(1)degrees, V = 744.6 angstrom(3), Z = 2, R-gt(F) = 0.080, wR(ref)(F-2) = 0.247, T = 293 K.",
journal = "Zeitschrift für Kristallographie - New Crystal Structures",
title = "Crystal structure of ethylenediammonium-N,N '-di-3-propionic acid tetrachloroplatinate(II), (CH2NH2(CH2)(2)COOH)(2)[PtCl4]",
volume = "221",
number = "3",
pages = "345-346",
doi = "10.1524/ncrs.2006.0103"
}
Kaluđerović, G. N., Bogdanović, G. A.,& Sabo, T. J.. (2006). Crystal structure of ethylenediammonium-N,N '-di-3-propionic acid tetrachloroplatinate(II), (CH2NH2(CH2)(2)COOH)(2)[PtCl4]. in Zeitschrift für Kristallographie - New Crystal Structures, 221(3), 345-346.
https://doi.org/10.1524/ncrs.2006.0103
Kaluđerović GN, Bogdanović GA, Sabo TJ. Crystal structure of ethylenediammonium-N,N '-di-3-propionic acid tetrachloroplatinate(II), (CH2NH2(CH2)(2)COOH)(2)[PtCl4]. in Zeitschrift für Kristallographie - New Crystal Structures. 2006;221(3):345-346.
doi:10.1524/ncrs.2006.0103 .
Kaluđerović, Goran N., Bogdanović, Goran A., Sabo, Tibor J., "Crystal structure of ethylenediammonium-N,N '-di-3-propionic acid tetrachloroplatinate(II), (CH2NH2(CH2)(2)COOH)(2)[PtCl4]" in Zeitschrift für Kristallographie - New Crystal Structures, 221, no. 3 (2006):345-346,
https://doi.org/10.1524/ncrs.2006.0103 . .
2
2

Syntheses and activity of some platinum(IV) complexes with N-methyl derivate of glycine and halogeno ligands against HeLa, K562 cell lines and human PBMC

Sabo, Tibor J.; Dinovic, VA; Kaluđerović, Goran N.; Stanojković, Tatjana P.; Bogdanović, Goran A.; Juranic, ZD

(2005)

TY  - JOUR
AU  - Sabo, Tibor J.
AU  - Dinovic, VA
AU  - Kaluđerović, Goran N.
AU  - Stanojković, Tatjana P.
AU  - Bogdanović, Goran A.
AU  - Juranic, ZD
PY  - 2005
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2876
AB  - Four platinum(IV) complexes, trans,trans-dichlorobis(N,N-dimethylglycinato)platinum(IV), trans,trans-[Pt(dmgly)(2)Cl-2] (1) and trans.trans-dibromobis(N,N-dimethylglycinato)platinum(IV), trans,trans-[Pt(dmgly)(2)Br-2] (2), as well as, trans,trans-dichlorobis(N-methylglycinato)platinum(IV), trans,trans-[Pt(sar)(2)Cl-2] (3) and trans,trans-dibromobis(N-methylglycinato)platinum(IV), trans,trans-[Pt(sar)(2)Br-2] (4) (with configuration index for all complexes OC-6-14), were synthesized and characterized by elemental analysis, infrared and H-1 NMR spectroscopy. In the aim to assess the selectivity in the antitumor action of these complexes, the antiproliferative action of these compounds was determined to human adenocarcinoma HeLa cells; to human myelogenous leukemia K562 cells and to normal immunocompetent cells; i.e., on human PBMC. The details of the crystal structure synthesized trans,trans-[Pt(sar)(2)Br-2] complex were also reported here. In the crystal structure of trans, trans-[Pt(sar)(2)Br-2] the Pt(IV) ion had a deformed octahedral coordination with both N-methylglycinates and bromides bonded trans to one another and with the NPt-Br bond angles of 84.1(4) and 95.9(4)degrees. The trans, trans-[Pt(sar)(2)Br-2] complex molecules form 2D-layers with multiple N-H (...) O and C-H (...) O hydrogen bonds. (c) 2005 Elsevier B.V. All rights reserved.
T2  - Inorganica Chimica Acta
T1  - Syntheses and activity of some platinum(IV) complexes with N-methyl derivate of glycine and halogeno ligands against HeLa, K562 cell lines and human PBMC
VL  - 358
IS  - 7
SP  - 2239
EP  - 2245
DO  - 10.1016/j.ica.2005.01.007
ER  - 
@article{
author = "Sabo, Tibor J. and Dinovic, VA and Kaluđerović, Goran N. and Stanojković, Tatjana P. and Bogdanović, Goran A. and Juranic, ZD",
year = "2005",
abstract = "Four platinum(IV) complexes, trans,trans-dichlorobis(N,N-dimethylglycinato)platinum(IV), trans,trans-[Pt(dmgly)(2)Cl-2] (1) and trans.trans-dibromobis(N,N-dimethylglycinato)platinum(IV), trans,trans-[Pt(dmgly)(2)Br-2] (2), as well as, trans,trans-dichlorobis(N-methylglycinato)platinum(IV), trans,trans-[Pt(sar)(2)Cl-2] (3) and trans,trans-dibromobis(N-methylglycinato)platinum(IV), trans,trans-[Pt(sar)(2)Br-2] (4) (with configuration index for all complexes OC-6-14), were synthesized and characterized by elemental analysis, infrared and H-1 NMR spectroscopy. In the aim to assess the selectivity in the antitumor action of these complexes, the antiproliferative action of these compounds was determined to human adenocarcinoma HeLa cells; to human myelogenous leukemia K562 cells and to normal immunocompetent cells; i.e., on human PBMC. The details of the crystal structure synthesized trans,trans-[Pt(sar)(2)Br-2] complex were also reported here. In the crystal structure of trans, trans-[Pt(sar)(2)Br-2] the Pt(IV) ion had a deformed octahedral coordination with both N-methylglycinates and bromides bonded trans to one another and with the NPt-Br bond angles of 84.1(4) and 95.9(4)degrees. The trans, trans-[Pt(sar)(2)Br-2] complex molecules form 2D-layers with multiple N-H (...) O and C-H (...) O hydrogen bonds. (c) 2005 Elsevier B.V. All rights reserved.",
journal = "Inorganica Chimica Acta",
title = "Syntheses and activity of some platinum(IV) complexes with N-methyl derivate of glycine and halogeno ligands against HeLa, K562 cell lines and human PBMC",
volume = "358",
number = "7",
pages = "2239-2245",
doi = "10.1016/j.ica.2005.01.007"
}
Sabo, T. J., Dinovic, V., Kaluđerović, G. N., Stanojković, T. P., Bogdanović, G. A.,& Juranic, Z.. (2005). Syntheses and activity of some platinum(IV) complexes with N-methyl derivate of glycine and halogeno ligands against HeLa, K562 cell lines and human PBMC. in Inorganica Chimica Acta, 358(7), 2239-2245.
https://doi.org/10.1016/j.ica.2005.01.007
Sabo TJ, Dinovic V, Kaluđerović GN, Stanojković TP, Bogdanović GA, Juranic Z. Syntheses and activity of some platinum(IV) complexes with N-methyl derivate of glycine and halogeno ligands against HeLa, K562 cell lines and human PBMC. in Inorganica Chimica Acta. 2005;358(7):2239-2245.
doi:10.1016/j.ica.2005.01.007 .
Sabo, Tibor J., Dinovic, VA, Kaluđerović, Goran N., Stanojković, Tatjana P., Bogdanović, Goran A., Juranic, ZD, "Syntheses and activity of some platinum(IV) complexes with N-methyl derivate of glycine and halogeno ligands against HeLa, K562 cell lines and human PBMC" in Inorganica Chimica Acta, 358, no. 7 (2005):2239-2245,
https://doi.org/10.1016/j.ica.2005.01.007 . .
21
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23

Aerosol synthesis of pure and Pt-doped ZnO particles using nitrate and pdda-Pt(IV) complex solutions

Djinovic, VM; Mančić, Lidija; Bogdanović, Goran A.; Vulic, PJ; del Rosario, G; Sabo, Tibor J.; Milošević, Olivera

(2005)

TY  - JOUR
AU  - Djinovic, VM
AU  - Mančić, Lidija
AU  - Bogdanović, Goran A.
AU  - Vulic, PJ
AU  - del Rosario, G
AU  - Sabo, Tibor J.
AU  - Milošević, Olivera
PY  - 2005
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2889
AB  - Pure and Pt-doped ZnO nanophase particles were synthesized by ultrasonic spray pyrolysis. The particles were obtained through the decomposition of zinc nitrate and with a newly developed Pt(IV) complex with 1,3 -propylenediamine-NN-diacetate tetradentate class ligand (pdda). The complex was characterized by elemental analysis, electronic absorption and infrared spectroscopy. The form of the determined complex structure {trans-[Pt(pdda)Br-2]center dot H2O} implies that Pt(IV) ion has a distorted octahedral coordination due to intramolecular N-H center dot center dot center dot Br interaction. The results of structural refinement (cell parameters, bond lengths, and ion occupancy) of ultrasonically derived pure and Pt-doped ZnO particles suggest either the formation of Zn-i interstitials or platinum ion incorporation into the ZnO lattice in octahedral interstitial positions, respectively. A well-crystallized hexagonal wurtzite structure of ZnO was pronounced in all investigated samples [JCPDS card 36-1415, Joint Committee on Powder Diffraction Standards, defined by International Centre for Diffraction Data (www.icdd.com)]. Phase determination also indicated the presence of a nitrate hydroxide hydrate phase (JCPDS card 24-1460), as a result of incomplete precursor decomposition and a spinel Zn2PtO4 phase (below 1.0 wt%) located in the boundary region for a Pt-doped ZnO sample. Based on x-ray diffraction, scanning electron microscopy, and energy-dispersive spectroscopy analyses, it was shown that the different particle growing morphologies, which were either spheroidally or pyramidally shaped, were influenced by the precursor chemistry, processing parameters and the presence of platinum ions. The composite internal particle structure revealed by transmission electron microscopy and selected area electron diffraction analyses, implied that the secondary particles represent an assembly of primary particles sized under 60 nm aroused during the processes of nucleation, growth and aggregation. Both hexagonal and spheroidal shape of primary particles was evident. The particle morphology, primarily particle size and the mechanism of Pt4+ ion introduction into the ZnO cell was discussed based on the structural refinement and selected area electron diffraction analysis.
T2  - Journal of Materials Research
T1  - Aerosol synthesis of pure and Pt-doped ZnO particles using nitrate and pdda-Pt(IV) complex solutions
VL  - 20
IS  - 1
SP  - 102
EP  - 113
DO  - 10.1557/JMR.2005.0006
ER  - 
@article{
author = "Djinovic, VM and Mančić, Lidija and Bogdanović, Goran A. and Vulic, PJ and del Rosario, G and Sabo, Tibor J. and Milošević, Olivera",
year = "2005",
abstract = "Pure and Pt-doped ZnO nanophase particles were synthesized by ultrasonic spray pyrolysis. The particles were obtained through the decomposition of zinc nitrate and with a newly developed Pt(IV) complex with 1,3 -propylenediamine-NN-diacetate tetradentate class ligand (pdda). The complex was characterized by elemental analysis, electronic absorption and infrared spectroscopy. The form of the determined complex structure {trans-[Pt(pdda)Br-2]center dot H2O} implies that Pt(IV) ion has a distorted octahedral coordination due to intramolecular N-H center dot center dot center dot Br interaction. The results of structural refinement (cell parameters, bond lengths, and ion occupancy) of ultrasonically derived pure and Pt-doped ZnO particles suggest either the formation of Zn-i interstitials or platinum ion incorporation into the ZnO lattice in octahedral interstitial positions, respectively. A well-crystallized hexagonal wurtzite structure of ZnO was pronounced in all investigated samples [JCPDS card 36-1415, Joint Committee on Powder Diffraction Standards, defined by International Centre for Diffraction Data (www.icdd.com)]. Phase determination also indicated the presence of a nitrate hydroxide hydrate phase (JCPDS card 24-1460), as a result of incomplete precursor decomposition and a spinel Zn2PtO4 phase (below 1.0 wt%) located in the boundary region for a Pt-doped ZnO sample. Based on x-ray diffraction, scanning electron microscopy, and energy-dispersive spectroscopy analyses, it was shown that the different particle growing morphologies, which were either spheroidally or pyramidally shaped, were influenced by the precursor chemistry, processing parameters and the presence of platinum ions. The composite internal particle structure revealed by transmission electron microscopy and selected area electron diffraction analyses, implied that the secondary particles represent an assembly of primary particles sized under 60 nm aroused during the processes of nucleation, growth and aggregation. Both hexagonal and spheroidal shape of primary particles was evident. The particle morphology, primarily particle size and the mechanism of Pt4+ ion introduction into the ZnO cell was discussed based on the structural refinement and selected area electron diffraction analysis.",
journal = "Journal of Materials Research",
title = "Aerosol synthesis of pure and Pt-doped ZnO particles using nitrate and pdda-Pt(IV) complex solutions",
volume = "20",
number = "1",
pages = "102-113",
doi = "10.1557/JMR.2005.0006"
}
Djinovic, V., Mančić, L., Bogdanović, G. A., Vulic, P., del Rosario, G., Sabo, T. J.,& Milošević, O.. (2005). Aerosol synthesis of pure and Pt-doped ZnO particles using nitrate and pdda-Pt(IV) complex solutions. in Journal of Materials Research, 20(1), 102-113.
https://doi.org/10.1557/JMR.2005.0006
Djinovic V, Mančić L, Bogdanović GA, Vulic P, del Rosario G, Sabo TJ, Milošević O. Aerosol synthesis of pure and Pt-doped ZnO particles using nitrate and pdda-Pt(IV) complex solutions. in Journal of Materials Research. 2005;20(1):102-113.
doi:10.1557/JMR.2005.0006 .
Djinovic, VM, Mančić, Lidija, Bogdanović, Goran A., Vulic, PJ, del Rosario, G, Sabo, Tibor J., Milošević, Olivera, "Aerosol synthesis of pure and Pt-doped ZnO particles using nitrate and pdda-Pt(IV) complex solutions" in Journal of Materials Research, 20, no. 1 (2005):102-113,
https://doi.org/10.1557/JMR.2005.0006 . .
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11

Synthesis and crystal structure of trans-dichloro(1,3-propylenediamine-N,N -diacetato)platinum(IV) monohydrate

Dinovic, VM; Bogdanović, Goran A.; Novaković, Slađana B.; Sabo, Tibor J.

(2004)

TY  - JOUR
AU  - Dinovic, VM
AU  - Bogdanović, Goran A.
AU  - Novaković, Slađana B.
AU  - Sabo, Tibor J.
PY  - 2004
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2787
AB  - The trans-geometrical isomer of the first Pt(IV) complex with the tetradentate ligand 1,3-propylenediamine-N,N-diacetate ion (pdda) was prepared by a direct synthesis from potassium hexachloroplatinate(IV) and pdda in the presence of lithium hydroxide. The crystal structure of trans-[Pt(pdda)Cl-2] (.) H2O complex has been determined. The Pt(IV) ion has a distorted octahedral coordination due to intramolecular N-(HCl)-Cl-... interactions.
T2  - Journal of Coordination Chemistry
T1  - Synthesis and crystal structure of trans-dichloro(1,3-propylenediamine-N,N -diacetato)platinum(IV) monohydrate
VL  - 57
IS  - 7
SP  - 535
EP  - 541
DO  - 10.1080/00958970410001671110
ER  - 
@article{
author = "Dinovic, VM and Bogdanović, Goran A. and Novaković, Slađana B. and Sabo, Tibor J.",
year = "2004",
abstract = "The trans-geometrical isomer of the first Pt(IV) complex with the tetradentate ligand 1,3-propylenediamine-N,N-diacetate ion (pdda) was prepared by a direct synthesis from potassium hexachloroplatinate(IV) and pdda in the presence of lithium hydroxide. The crystal structure of trans-[Pt(pdda)Cl-2] (.) H2O complex has been determined. The Pt(IV) ion has a distorted octahedral coordination due to intramolecular N-(HCl)-Cl-... interactions.",
journal = "Journal of Coordination Chemistry",
title = "Synthesis and crystal structure of trans-dichloro(1,3-propylenediamine-N,N -diacetato)platinum(IV) monohydrate",
volume = "57",
number = "7",
pages = "535-541",
doi = "10.1080/00958970410001671110"
}
Dinovic, V., Bogdanović, G. A., Novaković, S. B.,& Sabo, T. J.. (2004). Synthesis and crystal structure of trans-dichloro(1,3-propylenediamine-N,N -diacetato)platinum(IV) monohydrate. in Journal of Coordination Chemistry, 57(7), 535-541.
https://doi.org/10.1080/00958970410001671110
Dinovic V, Bogdanović GA, Novaković SB, Sabo TJ. Synthesis and crystal structure of trans-dichloro(1,3-propylenediamine-N,N -diacetato)platinum(IV) monohydrate. in Journal of Coordination Chemistry. 2004;57(7):535-541.
doi:10.1080/00958970410001671110 .
Dinovic, VM, Bogdanović, Goran A., Novaković, Slađana B., Sabo, Tibor J., "Synthesis and crystal structure of trans-dichloro(1,3-propylenediamine-N,N -diacetato)platinum(IV) monohydrate" in Journal of Coordination Chemistry, 57, no. 7 (2004):535-541,
https://doi.org/10.1080/00958970410001671110 . .
10
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10

Synthesis and crystal structure of trans-dichloro(ethylenediamine-N,N -di-3-propionato)platinum(IV) monohydrate

Kaluđerović, Goran N.; Bogdanović, Goran A.; Sabo, Tibor J.

(2002)

TY  - JOUR
AU  - Kaluđerović, Goran N.
AU  - Bogdanović, Goran A.
AU  - Sabo, Tibor J.
PY  - 2002
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2539
AB  - This paper reports the first synthesized Pt(IV) complex with ethylenediamine-N,N-di-3-propionato ligand (eddp). The crystal structure of trans-[Pt(eddp)Cl-2] . H2O complex has been determined. Pt(IV) has a distorted octahedral coordination due to an intramolecular N-H...Cl interaction.
T2  - Journal of Coordination Chemistry
T1  - Synthesis and crystal structure of trans-dichloro(ethylenediamine-N,N -di-3-propionato)platinum(IV) monohydrate
VL  - 55
IS  - 7
SP  - 817
EP  - 822
DO  - 10.1080/0095897022000001566
ER  - 
@article{
author = "Kaluđerović, Goran N. and Bogdanović, Goran A. and Sabo, Tibor J.",
year = "2002",
abstract = "This paper reports the first synthesized Pt(IV) complex with ethylenediamine-N,N-di-3-propionato ligand (eddp). The crystal structure of trans-[Pt(eddp)Cl-2] . H2O complex has been determined. Pt(IV) has a distorted octahedral coordination due to an intramolecular N-H...Cl interaction.",
journal = "Journal of Coordination Chemistry",
title = "Synthesis and crystal structure of trans-dichloro(ethylenediamine-N,N -di-3-propionato)platinum(IV) monohydrate",
volume = "55",
number = "7",
pages = "817-822",
doi = "10.1080/0095897022000001566"
}
Kaluđerović, G. N., Bogdanović, G. A.,& Sabo, T. J.. (2002). Synthesis and crystal structure of trans-dichloro(ethylenediamine-N,N -di-3-propionato)platinum(IV) monohydrate. in Journal of Coordination Chemistry, 55(7), 817-822.
https://doi.org/10.1080/0095897022000001566
Kaluđerović GN, Bogdanović GA, Sabo TJ. Synthesis and crystal structure of trans-dichloro(ethylenediamine-N,N -di-3-propionato)platinum(IV) monohydrate. in Journal of Coordination Chemistry. 2002;55(7):817-822.
doi:10.1080/0095897022000001566 .
Kaluđerović, Goran N., Bogdanović, Goran A., Sabo, Tibor J., "Synthesis and crystal structure of trans-dichloro(ethylenediamine-N,N -di-3-propionato)platinum(IV) monohydrate" in Journal of Coordination Chemistry, 55, no. 7 (2002):817-822,
https://doi.org/10.1080/0095897022000001566 . .
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Synthesis and crystal structure of s-cis-(ethylenediamine-N,N -diacetato)cobalt(III) complex with N,N-dimethylglycine

Dinovic, VM; Bogdanović, Goran A.; Novaković, Slađana B.; Sabo, Tibor J.

(2002)

TY  - JOUR
AU  - Dinovic, VM
AU  - Bogdanović, Goran A.
AU  - Novaković, Slađana B.
AU  - Sabo, Tibor J.
PY  - 2002
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2541
AB  - The s-cis-geometrical isomer of the cobalt(III) complex with N,N-dimethylglycine (dmgly) and the tetradentate ligand ethylenediamine-N,N-diacetate ion (edda) was prepared by a direct synthesis from cobalt(II) chloride hexahydrate, N,N-dimethylglycine and edda in the presence of lead(IV) oxide. The complex has been isolated chromatographically and characterized by elemental analyses, electron absorption spectra, infrared spectra and X-ray diffraction analysis.
T2  - Synthesis and Reactivity in Inorganic and Metal-organic Chemistry
T1  - Synthesis and crystal structure of s-cis-(ethylenediamine-N,N -diacetato)cobalt(III) complex with N,N-dimethylglycine
VL  - 32
IS  - 6
SP  - 1085
EP  - 1097
DO  - 10.1081/SIM-120013022
ER  - 
@article{
author = "Dinovic, VM and Bogdanović, Goran A. and Novaković, Slađana B. and Sabo, Tibor J.",
year = "2002",
abstract = "The s-cis-geometrical isomer of the cobalt(III) complex with N,N-dimethylglycine (dmgly) and the tetradentate ligand ethylenediamine-N,N-diacetate ion (edda) was prepared by a direct synthesis from cobalt(II) chloride hexahydrate, N,N-dimethylglycine and edda in the presence of lead(IV) oxide. The complex has been isolated chromatographically and characterized by elemental analyses, electron absorption spectra, infrared spectra and X-ray diffraction analysis.",
journal = "Synthesis and Reactivity in Inorganic and Metal-organic Chemistry",
title = "Synthesis and crystal structure of s-cis-(ethylenediamine-N,N -diacetato)cobalt(III) complex with N,N-dimethylglycine",
volume = "32",
number = "6",
pages = "1085-1097",
doi = "10.1081/SIM-120013022"
}
Dinovic, V., Bogdanović, G. A., Novaković, S. B.,& Sabo, T. J.. (2002). Synthesis and crystal structure of s-cis-(ethylenediamine-N,N -diacetato)cobalt(III) complex with N,N-dimethylglycine. in Synthesis and Reactivity in Inorganic and Metal-organic Chemistry, 32(6), 1085-1097.
https://doi.org/10.1081/SIM-120013022
Dinovic V, Bogdanović GA, Novaković SB, Sabo TJ. Synthesis and crystal structure of s-cis-(ethylenediamine-N,N -diacetato)cobalt(III) complex with N,N-dimethylglycine. in Synthesis and Reactivity in Inorganic and Metal-organic Chemistry. 2002;32(6):1085-1097.
doi:10.1081/SIM-120013022 .
Dinovic, VM, Bogdanović, Goran A., Novaković, Slađana B., Sabo, Tibor J., "Synthesis and crystal structure of s-cis-(ethylenediamine-N,N -diacetato)cobalt(III) complex with N,N-dimethylglycine" in Synthesis and Reactivity in Inorganic and Metal-organic Chemistry, 32, no. 6 (2002):1085-1097,
https://doi.org/10.1081/SIM-120013022 . .
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4
4

Crystal structure of ammonium iminodiacetate, NH4C4H6NO4

Marković, Z. B.; Bogdanović, Goran A.; Spasojević-de Bire, Anne; Sabo, Tibor J.; Trifunović, Srećko R.

(2000)

TY  - JOUR
AU  - Marković, Z. B.
AU  - Bogdanović, Goran A.
AU  - Spasojević-de Bire, Anne
AU  - Sabo, Tibor J.
AU  - Trifunović, Srećko R.
PY  - 2000
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2361
AB  - C4H10N2O4, orthorhombic, Pccn (No. 56), a = 7.782(2) Angstrom, b = 8.642(2) Angstrom, c = 10.230(3) Angstrom, V = 688.0 Angstrom(3), Z = 4, R-gt(F) = 0.071, wR(ref)(F-2) = 0.215, T = 293 K.
T2  - Zeitschrift für Kristallographie - New Crystal Structures
T1  - Crystal structure of ammonium iminodiacetate, NH4C4H6NO4
VL  - 215
IS  - 3
SP  - 363
EP  - 364
DO  - 10.1515/ncrs-2000-0328
UR  - https://hdl.handle.net/21.15107/rcub_vinar_2361
ER  - 
@article{
author = "Marković, Z. B. and Bogdanović, Goran A. and Spasojević-de Bire, Anne and Sabo, Tibor J. and Trifunović, Srećko R.",
year = "2000",
abstract = "C4H10N2O4, orthorhombic, Pccn (No. 56), a = 7.782(2) Angstrom, b = 8.642(2) Angstrom, c = 10.230(3) Angstrom, V = 688.0 Angstrom(3), Z = 4, R-gt(F) = 0.071, wR(ref)(F-2) = 0.215, T = 293 K.",
journal = "Zeitschrift für Kristallographie - New Crystal Structures",
title = "Crystal structure of ammonium iminodiacetate, NH4C4H6NO4",
volume = "215",
number = "3",
pages = "363-364",
doi = "10.1515/ncrs-2000-0328",
url = "https://hdl.handle.net/21.15107/rcub_vinar_2361"
}
Marković, Z. B., Bogdanović, G. A., Spasojević-de Bire, A., Sabo, T. J.,& Trifunović, S. R.. (2000). Crystal structure of ammonium iminodiacetate, NH4C4H6NO4. in Zeitschrift für Kristallographie - New Crystal Structures, 215(3), 363-364.
https://doi.org/10.1515/ncrs-2000-0328
https://hdl.handle.net/21.15107/rcub_vinar_2361
Marković ZB, Bogdanović GA, Spasojević-de Bire A, Sabo TJ, Trifunović SR. Crystal structure of ammonium iminodiacetate, NH4C4H6NO4. in Zeitschrift für Kristallographie - New Crystal Structures. 2000;215(3):363-364.
doi:10.1515/ncrs-2000-0328
https://hdl.handle.net/21.15107/rcub_vinar_2361 .
Marković, Z. B., Bogdanović, Goran A., Spasojević-de Bire, Anne, Sabo, Tibor J., Trifunović, Srećko R., "Crystal structure of ammonium iminodiacetate, NH4C4H6NO4" in Zeitschrift für Kristallographie - New Crystal Structures, 215, no. 3 (2000):363-364,
https://doi.org/10.1515/ncrs-2000-0328 .,
https://hdl.handle.net/21.15107/rcub_vinar_2361 .
2
2

Potassium 3-dithiocarboxy-3-aza-5-aminopentanoate dihydrate

Prelesnik, Bogdan V.; Anđelković, Katarina; Marković, Zorica; Sabo, Tibor J.; Trifunović, Snežana

(1997)

TY  - JOUR
AU  - Prelesnik, Bogdan V.
AU  - Anđelković, Katarina
AU  - Marković, Zorica
AU  - Sabo, Tibor J.
AU  - Trifunović, Snežana
PY  - 1997
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/2073
AB  - The synthesis and crystal structure of the title compound, K+. C5H9N2O2S2-. 2H(2)O, are described. The structure consists of potassium cations, 3-dithiocarboxy-3-aza-5-aminopentanoate anions and molecules of water. The anion exists in two tautomeric forms, each described by two resonance structures.
T2  - Acta Crystallographica. Section C: Crystal Structure Communications
T1  - Potassium 3-dithiocarboxy-3-aza-5-aminopentanoate dihydrate
VL  - 53
SP  - 719
EP  - 720
DO  - 10.1107/S0108270197001650
ER  - 
@article{
author = "Prelesnik, Bogdan V. and Anđelković, Katarina and Marković, Zorica and Sabo, Tibor J. and Trifunović, Snežana",
year = "1997",
abstract = "The synthesis and crystal structure of the title compound, K+. C5H9N2O2S2-. 2H(2)O, are described. The structure consists of potassium cations, 3-dithiocarboxy-3-aza-5-aminopentanoate anions and molecules of water. The anion exists in two tautomeric forms, each described by two resonance structures.",
journal = "Acta Crystallographica. Section C: Crystal Structure Communications",
title = "Potassium 3-dithiocarboxy-3-aza-5-aminopentanoate dihydrate",
volume = "53",
pages = "719-720",
doi = "10.1107/S0108270197001650"
}
Prelesnik, B. V., Anđelković, K., Marković, Z., Sabo, T. J.,& Trifunović, S.. (1997). Potassium 3-dithiocarboxy-3-aza-5-aminopentanoate dihydrate. in Acta Crystallographica. Section C: Crystal Structure Communications, 53, 719-720.
https://doi.org/10.1107/S0108270197001650
Prelesnik BV, Anđelković K, Marković Z, Sabo TJ, Trifunović S. Potassium 3-dithiocarboxy-3-aza-5-aminopentanoate dihydrate. in Acta Crystallographica. Section C: Crystal Structure Communications. 1997;53:719-720.
doi:10.1107/S0108270197001650 .
Prelesnik, Bogdan V., Anđelković, Katarina, Marković, Zorica, Sabo, Tibor J., Trifunović, Snežana, "Potassium 3-dithiocarboxy-3-aza-5-aminopentanoate dihydrate" in Acta Crystallographica. Section C: Crystal Structure Communications, 53 (1997):719-720,
https://doi.org/10.1107/S0108270197001650 . .
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