TY  - JOUR
AU  - Šuluburic, Adam
AU  - Milanovic, Svetlana
AU  - Vranješ-Đurić, Sanja
AU  - Jovanović, Ivan B.
AU  - Barna, Tomislav
AU  - Stojić, Milica
AU  - Fratric, Natalija
AU  - Szenci, Otto
AU  - Gvozdic, Dragan
PY  - 2017
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/1757
AB  - Early embryonic development may be negatively affected by insufficient progesterone (P4) production. Therefore, the aim of our study was to increase P4 by gonadotropin-releasing hormone (GnRH) and/or human chorionic gonadotropin (hCG) treatments after inducing oestrus by prostaglandin (PG) treatment. Lactating Simmental dairy cows (n = 110), between 1 to 5 lactations, with an average milk production of 6,500 l/305 days, at 40-80 days postpartum were used and grouped as follows: (1) PG + GnRH treatment at AI (GnRH group), (2) PG + hCG treatment at day 7 after AI (hCG group), (3) PG + GnRH at AI + hCG treatment at day 7 after AI (GnRH/hCG group), and (4) spontaneous oestrus (C: control group). All animals were double inseminated (at the time of oestrus detection and 12 +/- 2 h thereafter). Blood serum and milk samples were collected at the day of observed oestrus (day 0), and 14, 21 and 28 days after AI. Serum P4 was determined using a commercial radioimmunoassay (RIA) test (INEP, Zemun), and milk P4 was determined using enzyme-linked immunoassay (ELISA) test (NIV Novi Sad). Pregnancy status was confirmed by ultrasonography between days 28 and 35 after AI. Differences of serum or milk P4 medians, pregnancy (and calving) rate were determined using Dunns Multiple Comparison Tests and Z test, respectively. Serum P4 medians were significantly higher at days 14, 21 and 28 after AI in the hCG-treated animals, indicating increased luteal activity, with a similar tendency in whole milk P4 values. Treatment with hCG during the early luteal phase significantly contributed to the maintenance of gestation at days 28-35 after AI, and also increased the calving rate in Simmental dairy cows.
T2  - Acta Veterinaria Hungarica
T1  - Progesterone Concentration, Pregnancy and Calving Rate in Simmental Dairy Cows After Oestrus Synchronisation and Hcg Treatment During the Early Luteal Phase
VL  - 65
IS  - 3
SP  - 446
EP  - 458
DO  - 10.1556/004.2017.042
ER  - 

@article{
author = "Šuluburic, Adam and Milanovic, Svetlana and Vranješ-Đurić, Sanja and Jovanović, Ivan B. and Barna, Tomislav and Stojić, Milica and Fratric, Natalija and Szenci, Otto and Gvozdic, Dragan",
year = "2017",
abstract = "Early embryonic development may be negatively affected by insufficient progesterone (P4) production. Therefore, the aim of our study was to increase P4 by gonadotropin-releasing hormone (GnRH) and/or human chorionic gonadotropin (hCG) treatments after inducing oestrus by prostaglandin (PG) treatment. Lactating Simmental dairy cows (n = 110), between 1 to 5 lactations, with an average milk production of 6,500 l/305 days, at 40-80 days postpartum were used and grouped as follows: (1) PG + GnRH treatment at AI (GnRH group), (2) PG + hCG treatment at day 7 after AI (hCG group), (3) PG + GnRH at AI + hCG treatment at day 7 after AI (GnRH/hCG group), and (4) spontaneous oestrus (C: control group). All animals were double inseminated (at the time of oestrus detection and 12 +/- 2 h thereafter). Blood serum and milk samples were collected at the day of observed oestrus (day 0), and 14, 21 and 28 days after AI. Serum P4 was determined using a commercial radioimmunoassay (RIA) test (INEP, Zemun), and milk P4 was determined using enzyme-linked immunoassay (ELISA) test (NIV Novi Sad). Pregnancy status was confirmed by ultrasonography between days 28 and 35 after AI. Differences of serum or milk P4 medians, pregnancy (and calving) rate were determined using Dunns Multiple Comparison Tests and Z test, respectively. Serum P4 medians were significantly higher at days 14, 21 and 28 after AI in the hCG-treated animals, indicating increased luteal activity, with a similar tendency in whole milk P4 values. Treatment with hCG during the early luteal phase significantly contributed to the maintenance of gestation at days 28-35 after AI, and also increased the calving rate in Simmental dairy cows.",
journal = "Acta Veterinaria Hungarica",
title = "Progesterone Concentration, Pregnancy and Calving Rate in Simmental Dairy Cows After Oestrus Synchronisation and Hcg Treatment During the Early Luteal Phase",
volume = "65",
number = "3",
pages = "446-458",
doi = "10.1556/004.2017.042"
}

Šuluburic, A., Milanovic, S., Vranješ-Đurić, S., Jovanović, I. B., Barna, T., Stojić, M., Fratric, N., Szenci, O.,& Gvozdic, D.. (2017). Progesterone Concentration, Pregnancy and Calving Rate in Simmental Dairy Cows After Oestrus Synchronisation and Hcg Treatment During the Early Luteal Phase. in Acta Veterinaria Hungarica, 65(3), 446-458.
https://doi.org/10.1556/004.2017.042

Šuluburic A, Milanovic S, Vranješ-Đurić S, Jovanović IB, Barna T, Stojić M, Fratric N, Szenci O, Gvozdic D. Progesterone Concentration, Pregnancy and Calving Rate in Simmental Dairy Cows After Oestrus Synchronisation and Hcg Treatment During the Early Luteal Phase. in Acta Veterinaria Hungarica. 2017;65(3):446-458.
doi:10.1556/004.2017.042 .

Šuluburic, Adam, Milanovic, Svetlana, Vranješ-Đurić, Sanja, Jovanović, Ivan B., Barna, Tomislav, Stojić, Milica, Fratric, Natalija, Szenci, Otto, Gvozdic, Dragan, "Progesterone Concentration, Pregnancy and Calving Rate in Simmental Dairy Cows After Oestrus Synchronisation and Hcg Treatment During the Early Luteal Phase" in Acta Veterinaria Hungarica, 65, no. 3 (2017):446-458,
https://doi.org/10.1556/004.2017.042 . .

TY  - JOUR
AU  - Jovanović, Ivan B.
AU  - Velickovic, Miljan
AU  - Milanovic, Svetlana
AU  - Valcic, Olivera
AU  - Gvozdic, Dragan
AU  - Vranješ-Đurić, Sanja
PY  - 2015
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/626
AB  - The aim of this investigation was to determine the influence of oxidative stress upon general stress in dairy cows on parturition and whether the indicators of stress can be reduced by selenium (Se) supplementation. A total of 36 animals were divided into 3 groups 21 days prepartum and treated with a single-term intra muscular supplement of sodium selenite: Control group - 0 mg; group Se10 - 10 mg; group Se20 - 20 mg. Se supplementation significantly raised blood Se content and glutathione peroxidase (GPx) activity in groups Se10 and Se20, compared to Control, although there was no marked difference between supplemented groups. Plasma malondialdehyde (MDA) and cortisol concentrations were significantly reduced in supplemented groups Se10 and Se20, compared to Control. A negative correlation was detected between blood GPx activity and plasma MDA, while a positive correlation was determined between plasma MDA and cortisol concentrations. These results indicate that prepartum Se supplementation can be utilized for a partial relief of stress in cows during labor by augmenting the antioxidative action of GPx.
T2  - Acta Veterinaria, Beograd
T1  - Supplemental Selenium Reduces the Levels of Biomarkers of Oxidative and General Stress in Peripartum Dairy Cows
VL  - 65
IS  - 2
SP  - 191
EP  - 201
DO  - 10.1515/acve-2015-0016
ER  - 

@article{
author = "Jovanović, Ivan B. and Velickovic, Miljan and Milanovic, Svetlana and Valcic, Olivera and Gvozdic, Dragan and Vranješ-Đurić, Sanja",
year = "2015",
abstract = "The aim of this investigation was to determine the influence of oxidative stress upon general stress in dairy cows on parturition and whether the indicators of stress can be reduced by selenium (Se) supplementation. A total of 36 animals were divided into 3 groups 21 days prepartum and treated with a single-term intra muscular supplement of sodium selenite: Control group - 0 mg; group Se10 - 10 mg; group Se20 - 20 mg. Se supplementation significantly raised blood Se content and glutathione peroxidase (GPx) activity in groups Se10 and Se20, compared to Control, although there was no marked difference between supplemented groups. Plasma malondialdehyde (MDA) and cortisol concentrations were significantly reduced in supplemented groups Se10 and Se20, compared to Control. A negative correlation was detected between blood GPx activity and plasma MDA, while a positive correlation was determined between plasma MDA and cortisol concentrations. These results indicate that prepartum Se supplementation can be utilized for a partial relief of stress in cows during labor by augmenting the antioxidative action of GPx.",
journal = "Acta Veterinaria, Beograd",
title = "Supplemental Selenium Reduces the Levels of Biomarkers of Oxidative and General Stress in Peripartum Dairy Cows",
volume = "65",
number = "2",
pages = "191-201",
doi = "10.1515/acve-2015-0016"
}

Jovanović, I. B., Velickovic, M., Milanovic, S., Valcic, O., Gvozdic, D.,& Vranješ-Đurić, S.. (2015). Supplemental Selenium Reduces the Levels of Biomarkers of Oxidative and General Stress in Peripartum Dairy Cows. in Acta Veterinaria, Beograd, 65(2), 191-201.
https://doi.org/10.1515/acve-2015-0016

Jovanović IB, Velickovic M, Milanovic S, Valcic O, Gvozdic D, Vranješ-Đurić S. Supplemental Selenium Reduces the Levels of Biomarkers of Oxidative and General Stress in Peripartum Dairy Cows. in Acta Veterinaria, Beograd. 2015;65(2):191-201.
doi:10.1515/acve-2015-0016 .

Jovanović, Ivan B., Velickovic, Miljan, Milanovic, Svetlana, Valcic, Olivera, Gvozdic, Dragan, Vranješ-Đurić, Sanja, "Supplemental Selenium Reduces the Levels of Biomarkers of Oxidative and General Stress in Peripartum Dairy Cows" in Acta Veterinaria, Beograd, 65, no. 2 (2015):191-201,
https://doi.org/10.1515/acve-2015-0016 . .

TY  - JOUR
AU  - Matijatko, Vesna
AU  - Torti, Mann
AU  - Kis, Ivana
AU  - Smit, Iva
AU  - Stokovic, Igor
AU  - Vranješ-Đurić, Sanja
AU  - Milanovic, Svetlana
AU  - Mrljak, Vladimir
AU  - Brkljacic, Mirna
PY  - 2014
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/348
AB  - Babesiosis is an emerging tick-transmitted infectious disease of vertebrates that occurs worldwide. In Europe the predominant cause of canine babesiosis is Babesia canis. The disease can be clinically classified into uncomplicated and complicated forms. Both uncomplicated and complicated babesiosis due to Babesia canis appear to be the result of host inflammatory responses. The main aim of this study was to investigate the endocrine anti-inflammatory response in dogs naturally infected with Babesia canis. It was demonstrated that a marked endocrine response occurs in dogs naturally infected with Babesia canis, with significant increases in the concentration of cortisol and insulin. Statistically significant differences were found between the studied groups for all variables (cortisol, insulin and glucose) before the antibabesial treatment. The day after treatment a statistically significant difference was found between healthy dogs and the dogs that survived, as well as the dogs that died, for cortisol and glucose, but not for insulin. In all of the studied dog groups the median value of glucose was within the reference range, but one animal within the group of dogs that survived was hypoglycemic before the antibabesial treatment. After the antibabesial treatment all the studied animals had glucose values within the reference range. A statistically significant positive correlation was found between cortisol and insulin. The results of this study showed that concentrations of cortisol and insulin can be used to predict mortality in canine babesiosis caused by B. canis.
T2  - Veterinarski Arhiv
T1  - Serum cortisol and insulin concentrations in dogs naturally infected with Babesia canis
VL  - 84
IS  - 6
SP  - 551
EP  - 562
UR  - https://hdl.handle.net/21.15107/rcub_vinar_348
ER  - 

@article{
author = "Matijatko, Vesna and Torti, Mann and Kis, Ivana and Smit, Iva and Stokovic, Igor and Vranješ-Đurić, Sanja and Milanovic, Svetlana and Mrljak, Vladimir and Brkljacic, Mirna",
year = "2014",
abstract = "Babesiosis is an emerging tick-transmitted infectious disease of vertebrates that occurs worldwide. In Europe the predominant cause of canine babesiosis is Babesia canis. The disease can be clinically classified into uncomplicated and complicated forms. Both uncomplicated and complicated babesiosis due to Babesia canis appear to be the result of host inflammatory responses. The main aim of this study was to investigate the endocrine anti-inflammatory response in dogs naturally infected with Babesia canis. It was demonstrated that a marked endocrine response occurs in dogs naturally infected with Babesia canis, with significant increases in the concentration of cortisol and insulin. Statistically significant differences were found between the studied groups for all variables (cortisol, insulin and glucose) before the antibabesial treatment. The day after treatment a statistically significant difference was found between healthy dogs and the dogs that survived, as well as the dogs that died, for cortisol and glucose, but not for insulin. In all of the studied dog groups the median value of glucose was within the reference range, but one animal within the group of dogs that survived was hypoglycemic before the antibabesial treatment. After the antibabesial treatment all the studied animals had glucose values within the reference range. A statistically significant positive correlation was found between cortisol and insulin. The results of this study showed that concentrations of cortisol and insulin can be used to predict mortality in canine babesiosis caused by B. canis.",
journal = "Veterinarski Arhiv",
title = "Serum cortisol and insulin concentrations in dogs naturally infected with Babesia canis",
volume = "84",
number = "6",
pages = "551-562",
url = "https://hdl.handle.net/21.15107/rcub_vinar_348"
}

Matijatko, V., Torti, M., Kis, I., Smit, I., Stokovic, I., Vranješ-Đurić, S., Milanovic, S., Mrljak, V.,& Brkljacic, M.. (2014). Serum cortisol and insulin concentrations in dogs naturally infected with Babesia canis. in Veterinarski Arhiv, 84(6), 551-562.
https://hdl.handle.net/21.15107/rcub_vinar_348

Matijatko V, Torti M, Kis I, Smit I, Stokovic I, Vranješ-Đurić S, Milanovic S, Mrljak V, Brkljacic M. Serum cortisol and insulin concentrations in dogs naturally infected with Babesia canis. in Veterinarski Arhiv. 2014;84(6):551-562.
https://hdl.handle.net/21.15107/rcub_vinar_348 .

Matijatko, Vesna, Torti, Mann, Kis, Ivana, Smit, Iva, Stokovic, Igor, Vranješ-Đurić, Sanja, Milanovic, Svetlana, Mrljak, Vladimir, Brkljacic, Mirna, "Serum cortisol and insulin concentrations in dogs naturally infected with Babesia canis" in Veterinarski Arhiv, 84, no. 6 (2014):551-562,
https://hdl.handle.net/21.15107/rcub_vinar_348 .