TY  - JOUR
AU  - Vidotto, Monica
AU  - Grego, Timor
AU  - Petrović, Božana
AU  - Somers, Nicolas
AU  - Antonić Jelić, Tatjana
AU  - Kralj, Damir
AU  - Matijaković Mlinarić, Nives
AU  - Leriche, Anne
AU  - Dutour Sikirić, Maja
AU  - Erceg, Ina
AU  - Maltar-Strmečki, Nadica
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10186
AB  - To assess the application potential of novel biomaterials, their behaviour in model media and upon sterilization should be investigated, as well as the stability related to their storage condi-tions. Such data are lacking for Mg-substituted HAP (Mg-HAP). Therefore, the changes in the local structure of non-substituted and Mg-HAP after irradiation and immersion in corrected simulated fluid and saline solution for 28 days were followed by electron paramagnetic resonance (EPR) spectroscopy for the first time. To better understand the stability of radical species induced by steriliza-tion, EPR spectra of samples kept for 2 h at temperatures up to 373 K were recorded to provide an insight into the stability of the sample storage conditions by the accelerated aging method. Samples were characterized by PXRD, FTIR, SEM, EDS, AAS and TGA. Results confirmed that irradiation does not induce changes in the composition or the structure of any of the investigated materials. Fading or the complete disappearance of radical signals in the EPR spectra after immersion in both media was accompanied by the disappearance of other phases formed as a minor byproduct in the synthesis of substituted HAP, as confirmed by PXRD and FTIR analysis. Obtained results confirm the great potential of Mg-HAPs for biomedical applications, although closer attention should be given to the processes related to sample storage stability at different temperatures. © 2022 by the authors. Licensee MDPI, Basel, Switzerland.
T2  - Crystals
T1  - A Comparative EPR Study of Non-Substituted and Mg-Substituted Hydroxyapatite Behaviour in Model Media and during Accelerated Ageing
VL  - 12
IS  - 2
SP  - 297
DO  - 10.3390/cryst12020297
ER  - 

@article{
author = "Vidotto, Monica and Grego, Timor and Petrović, Božana and Somers, Nicolas and Antonić Jelić, Tatjana and Kralj, Damir and Matijaković Mlinarić, Nives and Leriche, Anne and Dutour Sikirić, Maja and Erceg, Ina and Maltar-Strmečki, Nadica",
year = "2022",
abstract = "To assess the application potential of novel biomaterials, their behaviour in model media and upon sterilization should be investigated, as well as the stability related to their storage condi-tions. Such data are lacking for Mg-substituted HAP (Mg-HAP). Therefore, the changes in the local structure of non-substituted and Mg-HAP after irradiation and immersion in corrected simulated fluid and saline solution for 28 days were followed by electron paramagnetic resonance (EPR) spectroscopy for the first time. To better understand the stability of radical species induced by steriliza-tion, EPR spectra of samples kept for 2 h at temperatures up to 373 K were recorded to provide an insight into the stability of the sample storage conditions by the accelerated aging method. Samples were characterized by PXRD, FTIR, SEM, EDS, AAS and TGA. Results confirmed that irradiation does not induce changes in the composition or the structure of any of the investigated materials. Fading or the complete disappearance of radical signals in the EPR spectra after immersion in both media was accompanied by the disappearance of other phases formed as a minor byproduct in the synthesis of substituted HAP, as confirmed by PXRD and FTIR analysis. Obtained results confirm the great potential of Mg-HAPs for biomedical applications, although closer attention should be given to the processes related to sample storage stability at different temperatures. © 2022 by the authors. Licensee MDPI, Basel, Switzerland.",
journal = "Crystals",
title = "A Comparative EPR Study of Non-Substituted and Mg-Substituted Hydroxyapatite Behaviour in Model Media and during Accelerated Ageing",
volume = "12",
number = "2",
pages = "297",
doi = "10.3390/cryst12020297"
}

Vidotto, M., Grego, T., Petrović, B., Somers, N., Antonić Jelić, T., Kralj, D., Matijaković Mlinarić, N., Leriche, A., Dutour Sikirić, M., Erceg, I.,& Maltar-Strmečki, N.. (2022). A Comparative EPR Study of Non-Substituted and Mg-Substituted Hydroxyapatite Behaviour in Model Media and during Accelerated Ageing. in Crystals, 12(2), 297.
https://doi.org/10.3390/cryst12020297

Vidotto M, Grego T, Petrović B, Somers N, Antonić Jelić T, Kralj D, Matijaković Mlinarić N, Leriche A, Dutour Sikirić M, Erceg I, Maltar-Strmečki N. A Comparative EPR Study of Non-Substituted and Mg-Substituted Hydroxyapatite Behaviour in Model Media and during Accelerated Ageing. in Crystals. 2022;12(2):297.
doi:10.3390/cryst12020297 .

Vidotto, Monica, Grego, Timor, Petrović, Božana, Somers, Nicolas, Antonić Jelić, Tatjana, Kralj, Damir, Matijaković Mlinarić, Nives, Leriche, Anne, Dutour Sikirić, Maja, Erceg, Ina, Maltar-Strmečki, Nadica, "A Comparative EPR Study of Non-Substituted and Mg-Substituted Hydroxyapatite Behaviour in Model Media and during Accelerated Ageing" in Crystals, 12, no. 2 (2022):297,
https://doi.org/10.3390/cryst12020297 . .